GREMLIN Database
YTZA - UPF0716 protein YtzA
UniProt: O32064 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 127 (115)
Sequences: 1272 (911)
Seq/√Len: 84.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
14_I90_L3.1501.00
60_D65_K3.1471.00
28_I32_V3.0291.00
38_T95_G2.8281.00
73_D108_K2.8271.00
22_L89_F2.8111.00
80_G98_L2.8091.00
58_Q62_Q2.6011.00
100_I103_T2.5761.00
17_G28_I2.4391.00
82_L86_L2.3471.00
18_I90_L2.2791.00
37_L41_I2.2751.00
97_C107_C2.1821.00
26_I30_P2.0941.00
11_F91_S2.0841.00
43_A85_M1.9731.00
55_Y58_Q1.9671.00
35_M38_T1.9531.00
19_F89_F1.7791.00
56_K70_A1.7141.00
29_L33_L1.6141.00
59_R63_Y1.5581.00
53_V77_I1.5391.00
57_V75_L1.5171.00
102_F106_W1.4880.99
86_L96_A1.4720.99
46_A81_G1.4150.99
79_I82_L1.3550.99
103_T106_W1.3500.99
76_C98_L1.2720.98
9_I12_P1.2580.98
13_A17_G1.2150.98
27_G31_T1.2080.98
76_C107_C1.1980.97
100_I106_W1.1900.97
16_I19_F1.1880.97
52_E56_K1.1860.97
10_V13_A1.1780.97
55_Y59_R1.1650.97
49_Q52_E1.1640.97
18_I22_L1.1280.96
22_L34_F1.1230.96
33_L37_L1.0990.96
59_R62_Q1.0900.95
38_T96_A1.0840.95
20_L23_G1.0780.95
114_W117_G1.0780.95
19_F90_L1.0600.95
19_F35_M1.0580.95
114_W118_M1.0530.95
73_D104_R1.0530.95
105_G108_K1.0380.94
46_A77_I1.0150.93
103_T108_K1.0010.93
80_G95_G0.9960.93
93_L97_C0.9880.92
113_K116_R0.9710.92
4_L43_A0.9690.92
64_G67_P0.9330.90
15_E49_Q0.9300.90
69_E112_F0.9290.90
49_Q99_L0.9260.90
73_D76_C0.9230.90
21_F24_N0.9170.89
80_G99_L0.8990.88
43_A86_L0.8980.88
23_G27_G0.8970.88
10_V43_A0.8840.88
69_E109_P0.8830.88
44_A48_K0.8740.87
57_V76_C0.8700.87
57_V61_L0.8690.87
53_V56_K0.8680.87
11_F90_L0.8610.86
16_I23_G0.8540.86
89_F92_D0.8470.85
106_W110_I0.8430.85
81_G85_M0.8370.85
57_V74_G0.8170.83
76_C111_L0.7890.81
14_I17_G0.7800.80
76_C108_K0.7700.79
80_G103_T0.7670.79
11_F86_L0.7640.79
23_G104_R0.7550.78
69_E72_A0.7430.77
26_I29_L0.7430.77
47_K51_T0.7410.77
25_L29_L0.7350.76
99_L103_T0.7310.76
38_T92_D0.7290.75
27_G30_P0.7290.75
38_T85_M0.7220.75
9_I39_G0.7180.74
8_F21_F0.7140.74
74_G95_G0.7130.74
17_G23_G0.7120.74
84_L95_G0.6960.72
7_L74_G0.6930.72
16_I78_F0.6910.72
57_V72_A0.6840.71
60_D70_A0.6750.70
45_A54_Y0.6710.69
21_F25_L0.6640.69
46_A80_G0.6630.68
15_E98_L0.6610.68
22_L39_G0.6580.68
61_L66_M0.6570.68
6_L11_F0.6560.68
39_G104_R0.6540.67
36_I40_I0.6530.67
51_T68_G0.6500.67
74_G78_F0.6460.66
8_F81_G0.6450.66
35_M95_G0.6430.66
16_I89_F0.6420.66
72_A114_W0.6300.64
107_C110_I0.6290.64
25_L30_P0.6250.64
13_A16_I0.6240.64
30_P33_L0.6200.63
6_L110_I0.6190.63
52_E57_V0.6180.63
46_A98_L0.6170.63
63_Y94_A0.6150.63
77_I104_R0.6120.62
99_L105_G0.6110.62
5_F8_F0.6090.62
90_L110_I0.6080.62
7_L12_P0.5950.60
69_E73_D0.5910.60
45_A49_Q0.5840.59
46_A78_F0.5840.59
14_I18_I0.5820.58
31_T36_I0.5820.58
54_Y75_L0.5790.58
32_V35_M0.5770.58
37_L93_L0.5760.58
60_D77_I0.5730.57
98_L103_T0.5720.57
7_L75_L0.5710.57
7_L36_I0.5700.57
45_A56_K0.5690.57
102_F105_G0.5670.56
32_V84_L0.5620.56
85_M91_S0.5620.56
59_R109_P0.5600.56
29_L36_I0.5580.55
36_I83_L0.5580.55
23_G26_I0.5520.54
12_P91_S0.5510.54
48_K113_K0.5480.54
13_A36_I0.5470.54
66_M79_I0.5470.54
34_F91_S0.5470.54
32_V116_R0.5460.54
81_G92_D0.5430.53
17_G21_F0.5420.53
15_E20_L0.5390.53
18_I40_I0.5380.53
90_L93_L0.5370.52
86_L92_D0.5360.52
29_L113_K0.5360.52
23_G28_I0.5340.52
64_G70_A0.5240.51
72_A75_L0.5100.49
21_F28_I0.5070.48
72_A76_C0.5070.48
18_I93_L0.5060.48
8_F16_I0.5020.48
4_L106_W0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4mt1A 3 0.8583 19.3 0.923 Contact Map
4dx5A 3 0.9213 14.8 0.927 Contact Map
2ipqX 1 0.5669 10.3 0.932 Contact Map
3w9iA 3 0.8504 9.8 0.933 Contact Map
3rkoA 1 0.4331 5.8 0.94 Contact Map
4k0jA 3 0.8031 5.4 0.94 Contact Map
3aqpA 1 0.9843 4.6 0.942 Contact Map
2xq2A 2 0.4016 2.8 0.948 Contact Map
2m20A 2 0.4331 2.1 0.951 Contact Map
3ne5A 3 0.8425 1.9 0.953 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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