SECDF - BACSU - GREMLIN Contacts

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SECDF - Protein translocase subunit SecDF

UniProt:	O32047	Sequences: MKKGRLIAFFLFVLLIGTGLGYFTKPAANNITLGLDLQGGFEVLYDVQPVKKGDKITKDVLVSTVEALNRRANVLGVSEPNIQIEGNNRIRVQLAGVTNQNRAREILATEAQLSFRDANDKELLNGADLVENGAKQTYDSTTNEPIVTIKLKDADKFGEVTKKVMKMAPNNQLVIWLDYDKGDSFKKEVQKEHPKFVSAPNVSQELNTTDVKIEGHFTAQEAKDLASILNAGALPVKLTEKYSTSVGAQFGQQALHDTVFAGIVGIAIIFLFMLFYYRLPGLIAVITLSVYIYITLQIFDWMNAVLTLPGIAALILGVGMAVDANIITYERIKEELKLGKSVRSAFRSGNRRSFATIFDANITTIIAAVVLFIFGTSSVKGFATMLILSILTSFITAVFLSRFLLALLVESRWLDRKKGWFGVNKKHIMDIQDTDENTEPHTPFQKWDFTSKRKYFFIFSSAVTVAGIIILLVFRLNLGIDFASGARIEVQSDHKLTTEQVEKDFESLGMDPDTVVLSGEKSNIGVARFVGVPDKETIAKVKTYFKDKYGSDPNVSTVSPTVGKELARNALYAVAIASIGIIIYVSIRFEYKMAIAAIASLLYDAFFIVTFFSITRLEVDVTFIAAILTIIGYSINDTIVTFDRVREHMKKRKPKTFADLNHIVNLSLQQTFTRSINTVLTVVIVVVTLLIFGASSITNFSIALLVGLLTGVYSSLYIAAQIWLAWKGRELKKDSAQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	737 (684)
Sequences:	14733 (9688)
Seq/√Len:	370.4

ECOLI - MDTB ACRD CUSA MDTC ACRF ACRB MDTF
BACSU - SECDF SWRC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
659_D	662_H	3.926	1.00
228_I	231_A	3.903	1.00
183_D	186_K	3.749	1.00
230_N	233_A	3.678	1.00
65_V	88_N	3.650	1.00
44_L	49_P	3.487	1.00
45_Y	49_P	3.287	1.00
445_Q	717_Y	3.259	1.00
611_F	706_V	3.219	1.00
234_L	237_K	3.183	1.00
341_S	344_S	3.052	1.00
235_P	238_L	3.048	1.00
447_W	665_N	2.998	1.00
223_K	252_Q	2.945	1.00
340_K	348_S	2.933	1.00
45_Y	48_Q	2.784	1.00
202_V	205_E	2.757	1.00
44_L	48_Q	2.729	1.00
531_G	534_D	2.723	1.00
65_V	84_I	2.722	1.00
43_V	49_P	2.690	1.00
136_Q	151_L	2.640	1.00
500_Q	503_K	2.634	1.00
199_A	202_V	2.588	1.00
194_P	202_V	2.582	1.00
593_M	646_R	2.568	1.00
294_I	392_T	2.556	1.00
443_P	669_Q	2.548	1.00
77_V	92_V	2.536	1.00
182_G	186_K	2.536	1.00
522_S	528_R	2.528	1.00
505_F	522_S	2.510	1.00
198_S	202_V	2.485	1.00
502_E	506_E	2.453	1.00
263_I	267_A	2.446	1.00
298_I	388_L	2.405	1.00
226_A	246_V	2.312	1.00
220_Q	224_D	2.299	1.00
43_V	48_Q	2.248	1.00
46_D	49_P	2.240	1.00
615_T	702_I	2.235	1.00
137_T	140_S	2.220	1.00
235_P	239_T	2.188	1.00
78_S	95_A	2.176	1.00
58_K	62_V	2.164	1.00
141_T	146_I	2.120	1.00
237_K	243_S	2.095	1.00
199_A	203_S	2.093	1.00
648_H	651_K	2.085	1.00
199_A	205_E	2.074	1.00
664_V	724_L	2.072	1.00
78_S	93_Q	2.069	1.00
543_T	547_D	2.041	1.00
451_S	661_N	2.041	1.00
540_K	544_Y	2.040	1.00
690_L	705_L	2.028	1.00
452_K	455_Y	2.024	1.00
260_F	264_V	2.002	1.00
661_N	724_L	2.001	1.00
542_K	546_K	1.986	1.00
649_M	723_W	1.984	1.00
136_Q	148_T	1.970	1.00
648_H	653_K	1.962	1.00
198_S	203_S	1.956	1.00
437_N	441_H	1.946	1.00
334_E	338_L	1.939	1.00
200_P	205_E	1.939	1.00
234_L	238_L	1.929	1.00
224_D	227_S	1.928	1.00
335_E	352_R	1.915	1.00
196_F	202_V	1.914	1.00
194_P	199_A	1.902	1.00
539_A	542_K	1.896	1.00
197_V	202_V	1.886	1.00
653_K	666_L	1.881	1.00
200_P	203_S	1.878	1.00
653_K	659_D	1.873	1.00
648_H	666_L	1.866	1.00
181_K	184_S	1.857	1.00
469_I	472_L	1.854	1.00
344_S	348_S	1.845	1.00
23_F	27_A	1.843	1.00
147_V	150_K	1.838	1.00
256_H	260_F	1.835	1.00
335_E	340_K	1.835	1.00
47_V	88_N	1.834	1.00
522_S	534_D	1.830	1.00
437_N	440_P	1.828	1.00
442_T	668_L	1.826	1.00
509_G	513_D	1.813	1.00
183_D	187_K	1.811	1.00
28_A	300_D	1.807	1.00
194_P	203_S	1.803	1.00
134_A	155_D	1.781	1.00
468_I	472_L	1.779	1.00
220_Q	223_K	1.778	1.00
448_D	451_S	1.773	1.00
462_A	466_A	1.749	1.00
522_S	529_F	1.744	1.00
235_P	243_S	1.725	1.00
492_S	496_L	1.722	1.00
194_P	198_S	1.719	1.00
646_R	650_K	1.718	1.00
448_D	452_K	1.709	1.00
223_K	227_S	1.707	1.00
539_A	543_T	1.696	1.00
194_P	204_Q	1.694	1.00
528_R	534_D	1.690	1.00
331_R	352_R	1.689	1.00
99_N	102_R	1.676	1.00
365_I	391_L	1.675	1.00
529_F	534_D	1.665	1.00
60_V	64_T	1.660	1.00
287_T	396_T	1.656	1.00
180_D	184_S	1.642	1.00
453_R	724_L	1.639	1.00
530_V	533_P	1.632	1.00
647_E	651_K	1.629	1.00
68_L	72_A	1.627	1.00
198_S	205_E	1.623	1.00
469_I	473_V	1.623	1.00
72_A	92_V	1.620	1.00
236_V	239_T	1.619	1.00
457_F	461_S	1.613	1.00
302_M	388_L	1.613	1.00
509_G	512_P	1.607	1.00
537_T	542_K	1.594	1.00
226_A	230_N	1.591	1.00
201_N	517_L	1.590	1.00
544_Y	547_D	1.587	1.00
149_I	153_D	1.584	1.00
194_P	205_E	1.565	1.00
234_L	239_T	1.560	1.00
441_H	444_F	1.549	1.00
233_A	239_T	1.546	1.00
537_T	541_V	1.544	1.00
198_S	201_N	1.544	1.00
197_V	203_S	1.538	1.00
457_F	725_A	1.534	1.00
76_G	98_T	1.532	1.00
617_L	702_I	1.529	1.00
92_V	107_L	1.528	1.00
537_T	540_K	1.517	1.00
194_P	200_P	1.514	1.00
224_D	228_I	1.506	1.00
443_P	447_W	1.490	1.00
140_S	143_N	1.487	1.00
304_A	384_T	1.484	1.00
582_I	594_A	1.484	1.00
683_V	705_L	1.479	1.00
490_V	505_F	1.474	1.00
257_D	260_F	1.473	1.00
153_D	157_F	1.473	1.00
68_L	90_I	1.472	1.00
540_K	543_T	1.467	1.00
530_V	534_D	1.459	1.00
25_K	297_Q	1.457	1.00
140_S	144_E	1.455	1.00
270_F	285_V	1.444	1.00
19_G	293_Y	1.442	1.00
216_H	221_E	1.442	1.00
464_T	468_I	1.442	1.00
533_P	536_E	1.422	1.00
334_E	670_Q	1.421	1.00
152_K	156_K	1.420	1.00
529_F	533_P	1.416	1.00
335_E	338_L	1.414	1.00
525_G	528_R	1.413	1.00
179_Y	185_F	1.410	1.00
123_L	133_G	1.409	1.00
332_I	405_L	1.404	1.00
649_M	727_K	1.401	1.00
496_L	500_Q	1.392	1.00
538_I	542_K	1.390	1.00
80_P	92_V	1.384	1.00
661_N	665_N	1.383	1.00
492_S	504_D	1.382	1.00
503_K	506_E	1.381	1.00
683_V	709_L	1.378	1.00
33_L	483_A	1.377	1.00
179_Y	188_E	1.377	1.00
72_A	90_I	1.375	1.00
522_S	525_G	1.370	1.00
56_I	59_D	1.369	1.00
267_A	271_L	1.369	1.00
562_V	565_E	1.367	1.00
76_G	95_A	1.367	1.00
384_T	388_L	1.366	1.00
441_H	445_Q	1.366	1.00
676_I	680_L	1.362	1.00
445_Q	448_D	1.361	1.00
236_V	243_S	1.361	1.00
600_S	638_T	1.346	1.00
295_T	389_S	1.345	1.00
65_V	82_I	1.337	1.00
150_K	153_D	1.336	1.00
228_I	232_G	1.333	1.00
331_R	334_E	1.332	1.00
199_A	502_E	1.331	1.00
44_L	47_V	1.331	1.00
18_T	294_I	1.331	1.00
477_N	618_E	1.326	1.00
612_F	623_F	1.320	1.00
153_D	156_K	1.316	1.00
340_K	344_S	1.308	1.00
504_D	507_S	1.305	1.00
531_G	535_K	1.304	1.00
136_Q	141_T	1.300	1.00
112_Q	115_F	1.299	1.00
84_I	88_N	1.293	1.00
662_H	666_L	1.292	1.00
649_M	660_L	1.290	1.00
146_I	150_K	1.289	1.00
234_L	243_S	1.288	1.00
444_F	448_D	1.285	1.00
98_T	103_A	1.284	1.00
503_K	507_S	1.284	1.00
21_G	297_Q	1.284	1.00
246_V	249_Q	1.278	1.00
252_Q	256_H	1.276	1.00
348_S	351_R	1.265	1.00
550_G	553_P	1.264	1.00
488_I	526_V	1.262	1.00
79_E	93_Q	1.257	1.00
194_P	197_V	1.257	1.00
43_V	47_V	1.253	1.00
523_N	526_V	1.242	1.00
197_V	205_E	1.241	1.00
443_P	666_L	1.236	1.00
509_G	515_V	1.235	1.00
444_F	447_W	1.233	1.00
150_K	191_K	1.231	1.00
199_A	204_Q	1.224	1.00
328_T	350_N	1.223	1.00
647_E	650_K	1.223	1.00
335_E	348_S	1.221	1.00
201_N	205_E	1.218	1.00
25_K	300_D	1.218	1.00
227_S	231_A	1.216	1.00
538_I	541_V	1.216	1.00
223_K	226_A	1.214	1.00
522_S	526_V	1.214	1.00
68_L	114_S	1.214	1.00
331_R	644_R	1.213	1.00
458_I	462_A	1.204	1.00
465_V	469_I	1.203	1.00
449_F	721_Q	1.201	1.00
193_H	202_V	1.200	1.00
298_I	302_M	1.197	1.00
465_V	468_I	1.196	1.00
60_V	84_I	1.193	1.00
440_P	444_F	1.192	1.00
610_T	614_I	1.192	1.00
568_R	571_L	1.190	1.00
617_L	698_T	1.190	1.00
155_D	188_E	1.188	1.00
608_I	627_I	1.188	1.00
108_A	112_Q	1.186	1.00
304_A	310_G	1.185	1.00
233_A	241_K	1.185	1.00
361_N	394_F	1.181	1.00
161_T	165_M	1.180	1.00
634_S	711_G	1.179	1.00
12_F	591_Y	1.177	1.00
72_A	107_L	1.174	1.00
532_V	536_E	1.172	1.00
102_R	106_I	1.171	1.00
196_F	203_S	1.170	1.00
259_V	263_I	1.169	1.00
391_L	395_I	1.168	1.00
660_L	664_V	1.168	1.00
239_T	243_S	1.167	1.00
343_R	347_R	1.166	1.00
497_T	500_Q	1.166	1.00
347_R	351_R	1.165	1.00
490_V	508_L	1.162	1.00
443_P	665_N	1.161	1.00
196_F	199_A	1.160	1.00
646_R	649_M	1.159	1.00
492_S	501_V	1.157	1.00
455_Y	458_I	1.157	1.00
362_I	584_Y	1.155	1.00
238_L	243_S	1.154	1.00
81_N	93_Q	1.151	1.00
473_V	613_S	1.151	1.00
239_T	242_Y	1.146	1.00
458_I	465_V	1.146	1.00
523_N	534_D	1.138	1.00
561_T	564_K	1.136	1.00
227_S	230_N	1.131	1.00
453_R	728_G	1.129	1.00
290_V	400_L	1.126	1.00
60_V	88_N	1.123	1.00
466_A	470_I	1.118	1.00
141_T	151_L	1.116	1.00
26_P	259_V	1.115	1.00
366_I	580_G	1.112	1.00
523_N	528_R	1.112	1.00
461_S	465_V	1.111	1.00
611_F	702_I	1.111	1.00
644_R	648_H	1.109	1.00
119_N	122_E	1.107	1.00
324_A	636_N	1.104	1.00
645_V	664_V	1.101	1.00
234_L	240_E	1.100	1.00
69_N	82_I	1.099	1.00
683_V	708_L	1.096	1.00
77_V	80_P	1.092	1.00
283_I	404_L	1.092	1.00
198_S	204_Q	1.091	1.00
257_D	697_I	1.091	1.00
344_S	347_R	1.089	1.00
217_F	220_Q	1.086	1.00
162_K	165_M	1.085	1.00
222_A	226_A	1.083	1.00
236_V	240_E	1.083	1.00
110_E	113_L	1.081	1.00
460_S	718_I	1.081	1.00
666_L	669_Q	1.080	1.00
359_D	584_Y	1.079	1.00
509_G	514_T	1.077	1.00
501_V	504_D	1.076	1.00
680_L	684_I	1.075	1.00
727_K	730_E	1.073	1.00
184_S	187_K	1.073	1.00
666_L	670_Q	1.072	1.00
532_V	535_K	1.072	1.00
71_R	113_L	1.069	1.00
46_D	88_N	1.069	1.00
237_K	240_E	1.069	1.00
333_K	337_K	1.068	1.00
354_F	358_F	1.067	1.00
449_F	456_F	1.065	1.00
502_E	505_F	1.065	1.00
525_G	534_D	1.063	1.00
405_L	409_V	1.061	1.00
118_A	122_E	1.059	1.00
15_L	400_L	1.057	1.00
164_V	175_I	1.056	1.00
505_F	508_L	1.056	1.00
477_N	620_D	1.052	1.00
332_I	349_G	1.052	1.00
298_I	392_T	1.051	1.00
528_R	531_G	1.043	1.00
19_G	23_F	1.037	1.00
375_G	569_N	1.035	1.00
331_R	335_E	1.032	1.00
575_A	579_I	1.032	1.00
516_V	529_F	1.031	1.00
43_V	46_D	1.026	1.00
115_F	123_L	1.026	1.00
446_K	450_T	1.022	1.00
342_V	346_F	1.022	1.00
679_V	712_V	1.021	1.00
331_R	353_S	1.020	1.00
13_V	583_I	1.020	1.00
436_E	440_P	1.017	1.00
71_R	114_S	1.016	1.00
236_V	242_Y	1.015	1.00
531_G	536_E	1.012	1.00
442_T	446_K	1.011	1.00
522_S	531_G	1.010	1.00
29_N	296_L	1.010	1.00
12_F	16_I	1.010	1.00
165_M	172_Q	1.009	1.00
644_R	670_Q	1.006	1.00
198_S	207_N	1.005	1.00
462_A	465_V	1.004	1.00
454_K	458_I	1.003	1.00
256_H	259_V	0.999	1.00
589_F	639_I	0.995	1.00
522_S	532_V	0.994	1.00
359_D	588_R	0.991	1.00
454_K	725_A	0.989	1.00
526_V	529_F	0.989	1.00
64_T	122_E	0.987	1.00
687_V	691_I	0.985	1.00
665_N	669_Q	0.984	1.00
221_E	224_D	0.983	1.00
194_P	201_N	0.981	1.00
525_G	531_G	0.978	1.00
154_A	188_E	0.978	1.00
78_S	565_E	0.975	1.00
10_F	587_I	0.972	1.00
558_V	561_T	0.971	1.00
102_R	105_E	0.968	1.00
652_R	666_L	0.968	1.00
522_S	527_A	0.967	1.00
360_A	394_F	0.963	1.00
450_T	724_L	0.962	1.00
72_A	80_P	0.960	1.00
98_T	106_I	0.960	1.00
451_S	454_K	0.958	1.00
68_L	111_A	0.957	1.00
653_K	662_H	0.957	1.00
200_P	204_Q	0.956	1.00
197_V	200_P	0.956	1.00
496_L	501_V	0.956	1.00
116_R	119_N	0.956	1.00
299_F	304_A	0.956	1.00
253_Q	256_H	0.955	1.00
541_V	545_F	0.955	1.00
541_V	557_T	0.953	1.00
434_T	437_N	0.951	1.00
352_R	647_E	0.951	1.00
71_R	117_D	0.946	1.00
571_L	575_A	0.946	1.00
434_T	438_T	0.946	1.00
687_V	705_L	0.943	1.00
603_Y	714_S	0.942	1.00
287_T	401_S	0.941	1.00
466_A	469_I	0.941	1.00
447_W	451_S	0.940	1.00
453_R	725_A	0.940	1.00
439_E	443_P	0.940	1.00
518_S	521_K	0.939	1.00
528_R	533_P	0.939	1.00
467_G	609_V	0.938	1.00
522_S	530_V	0.933	1.00
286_I	404_L	0.930	1.00
542_K	564_K	0.928	1.00
471_L	609_V	0.927	1.00
240_E	243_S	0.927	1.00
364_T	636_N	0.926	1.00
596_A	722_I	0.925	1.00
94_L	103_A	0.925	1.00
19_G	290_V	0.924	1.00
339_G	345_A	0.921	1.00
528_R	535_K	0.920	1.00
612_F	703_A	0.919	1.00
12_F	407_L	0.917	1.00
82_I	90_I	0.916	1.00
608_I	703_A	0.914	1.00
222_A	248_A	0.913	1.00
645_V	723_W	0.912	1.00
290_V	396_T	0.911	1.00
471_L	474_F	0.910	1.00
365_I	387_I	0.909	1.00
463_V	606_F	0.908	1.00
286_I	400_L	0.908	1.00
522_S	533_P	0.908	1.00
611_F	615_T	0.906	1.00
229_L	233_A	0.904	1.00
94_L	107_L	0.903	1.00
472_L	475_R	0.902	1.00
645_V	667_S	0.898	1.00
46_D	87_N	0.897	1.00
295_T	388_L	0.896	1.00
66_E	70_R	0.894	1.00
545_F	548_K	0.894	1.00
486_A	526_V	0.892	1.00
47_V	122_E	0.891	1.00
354_F	398_V	0.890	1.00
363_T	636_N	0.890	1.00
543_T	546_K	0.886	1.00
554_N	559_S	0.884	1.00
721_Q	724_L	0.883	1.00
518_S	528_R	0.883	1.00
299_F	385_M	0.882	1.00
336_L	342_V	0.882	1.00
264_V	267_A	0.878	1.00
501_V	505_F	0.878	1.00
470_I	610_T	0.877	1.00
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499_E	503_K	0.876	1.00
461_S	468_I	0.874	1.00
310_G	381_G	0.873	1.00
196_F	200_P	0.872	1.00
522_S	535_K	0.869	1.00
545_F	555_V	0.867	1.00
529_F	532_V	0.867	1.00
343_R	406_A	0.866	1.00
547_D	550_G	0.865	1.00
161_T	164_V	0.865	1.00
83_Q	91_R	0.865	1.00
196_F	205_E	0.863	1.00
514_T	529_F	0.863	1.00
226_A	242_Y	0.861	1.00
435_D	439_E	0.860	1.00
615_T	706_V	0.859	1.00
582_I	591_Y	0.859	1.00
436_E	439_E	0.858	1.00
648_H	670_Q	0.858	1.00
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449_F	717_Y	0.856	1.00
139_D	142_T	0.855	1.00
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249_Q	252_Q	0.849	1.00
679_V	683_V	0.848	1.00
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660_L	724_L	0.844	1.00
189_V	192_E	0.843	1.00
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526_V	534_D	0.834	1.00
226_A	248_A	0.833	1.00
297_Q	300_D	0.832	1.00
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226_A	233_A	0.830	1.00
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439_E	669_Q	0.827	1.00
36_D	215_G	0.827	1.00
637_D	711_G	0.826	1.00
456_F	459_F	0.826	1.00
74_V	110_E	0.822	1.00
715_S	719_A	0.821	1.00
518_S	523_N	0.821	1.00
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332_I	346_F	0.814	1.00
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470_I	613_S	0.814	1.00
372_F	384_T	0.813	1.00
686_V	705_L	0.812	1.00
518_S	522_S	0.812	1.00
595_I	599_A	0.811	1.00
287_T	325_N	0.810	1.00
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664_V	668_L	0.807	1.00
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24_T	28_A	0.802	1.00
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579_I	583_I	0.797	1.00
186_K	200_P	0.797	1.00
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387_I	391_L	0.796	1.00
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582_I	586_S	0.790	1.00
149_I	152_K	0.790	1.00
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234_L	242_Y	0.775	1.00
524_I	528_R	0.775	1.00
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509_G	517_L	0.770	1.00
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101_N	105_E	0.767	1.00
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337_K	412_R	0.765	1.00
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295_T	392_T	0.763	1.00
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470_I	474_F	0.762	1.00
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619_V	624_I	0.753	1.00
561_T	565_E	0.753	1.00
546_K	550_G	0.752	1.00
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619_V	623_F	0.750	1.00
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515_V	526_V	0.738	1.00
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724_L	728_G	0.731	1.00
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578_S	598_I	0.727	1.00
600_S	603_Y	0.726	1.00
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235_P	242_Y	0.720	1.00
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510_M	513_D	0.712	1.00
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141_T	144_E	0.711	0.99
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317_G	386_L	0.669	0.99
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294_I	298_I	0.660	0.99
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660_L	663_I	0.615	0.99
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268_I	684_I	0.604	0.98
279_L	409_V	0.604	0.98
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283_I	408_L	0.604	0.98
593_M	596_A	0.603	0.98
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499_E	502_E	0.602	0.98
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464_T	606_F	0.601	0.98
581_I	635_I	0.601	0.98
337_K	673_T	0.601	0.98
15_L	18_T	0.600	0.98
30_N	303_N	0.599	0.98
649_M	659_D	0.598	0.98
662_H	665_N	0.598	0.98
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521_K	534_D	0.595	0.98
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538_I	544_Y	0.594	0.98
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642_F	646_R	0.590	0.98
511_D	514_T	0.590	0.98
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649_M	663_I	0.576	0.98
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490_V	501_V	0.548	0.97
471_L	476_L	0.547	0.97
334_E	352_R	0.547	0.97
577_A	628_L	0.546	0.97
725_A	729_R	0.546	0.97
539_A	546_K	0.545	0.97
114_S	118_A	0.545	0.97
179_Y	184_S	0.544	0.97
32_T	36_D	0.544	0.97
248_A	251_G	0.544	0.97
262_G	266_I	0.543	0.97
591_Y	594_A	0.543	0.97
524_I	532_V	0.543	0.97
317_G	389_S	0.543	0.97
361_N	397_A	0.542	0.97
541_V	544_Y	0.542	0.97
687_V	690_L	0.541	0.97
435_D	676_I	0.541	0.97
542_K	547_D	0.540	0.97
573_A	576_I	0.539	0.97
176_W	184_S	0.539	0.97
702_I	706_V	0.539	0.97
18_T	396_T	0.539	0.97
659_D	663_I	0.539	0.97
24_T	27_A	0.537	0.97
34_G	308_L	0.537	0.97
266_I	269_I	0.537	0.97
542_K	557_T	0.536	0.97
294_I	395_I	0.536	0.97
115_F	118_A	0.536	0.97
607_F	706_V	0.534	0.96
163_K	167_M	0.534	0.96
361_N	365_I	0.533	0.96
488_I	524_I	0.532	0.96
287_T	291_Y	0.531	0.96
368_A	386_L	0.531	0.96
511_D	547_D	0.528	0.96
59_D	63_S	0.528	0.96
98_T	102_R	0.527	0.96
372_F	383_A	0.527	0.96
342_V	411_S	0.527	0.96
612_F	618_E	0.526	0.96
164_V	168_A	0.526	0.96
512_P	516_V	0.526	0.96
471_L	619_V	0.525	0.96
566_L	571_L	0.525	0.96
45_Y	72_A	0.524	0.96
527_A	531_G	0.524	0.96
67_A	71_R	0.524	0.96
260_F	267_A	0.524	0.96
600_S	604_D	0.524	0.96
161_T	176_W	0.522	0.96
270_F	288_L	0.522	0.96
475_R	616_R	0.521	0.96
299_F	314_L	0.521	0.96
468_I	473_V	0.521	0.96
592_K	729_R	0.521	0.96
283_I	401_S	0.521	0.96
525_G	535_K	0.521	0.96
45_Y	92_V	0.521	0.96
277_Y	330_E	0.521	0.96
29_N	299_F	0.520	0.96
76_G	106_I	0.519	0.96
505_F	524_I	0.519	0.96
549_Y	555_V	0.519	0.96
75_L	110_E	0.518	0.96
538_I	546_K	0.518	0.96
501_V	508_L	0.518	0.96
134_A	185_F	0.518	0.96
653_K	663_I	0.518	0.96
336_L	411_S	0.517	0.96
446_K	665_N	0.517	0.96
67_A	117_D	0.516	0.96
158_G	161_T	0.516	0.96
61_L	69_N	0.516	0.96
165_M	169_P	0.516	0.96
469_I	474_F	0.516	0.96
234_L	241_K	0.516	0.96
712_V	715_S	0.516	0.96
671_T	678_T	0.514	0.96
725_A	728_G	0.514	0.96
313_A	317_G	0.514	0.96
441_H	452_K	0.514	0.96
489_E	523_N	0.514	0.96
278_R	281_G	0.513	0.96
105_E	108_A	0.512	0.96
304_A	372_F	0.512	0.96
323_D	678_T	0.512	0.96
362_I	391_L	0.511	0.95
111_A	115_F	0.510	0.95
30_N	305_V	0.510	0.95
504_D	508_L	0.510	0.95
633_Y	682_V	0.510	0.95
174_V	177_L	0.510	0.95
75_L	107_L	0.509	0.95
633_Y	704_L	0.508	0.95
392_T	395_I	0.508	0.95
463_V	466_A	0.508	0.95
692_F	698_T	0.507	0.95
618_E	623_F	0.507	0.95
328_T	398_V	0.507	0.95
435_D	440_P	0.507	0.95
464_T	603_Y	0.506	0.95
327_I	357_I	0.506	0.95
269_I	281_G	0.505	0.95
294_I	396_T	0.505	0.95
60_V	65_V	0.504	0.95
441_H	448_D	0.504	0.95
11_L	403_F	0.504	0.95
637_D	712_V	0.504	0.95
453_R	457_F	0.504	0.95
444_F	451_S	0.503	0.95
576_I	580_G	0.502	0.95
29_N	306_L	0.502	0.95
521_K	526_V	0.502	0.95
453_R	661_N	0.501	0.95
168_A	172_Q	0.500	0.95
158_G	179_Y	0.500	0.95
721_Q	725_A	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4k0jA	3	0.9132	100	0.295	Contact Map
3ne5A	3	0.9444	100	0.358	Contact Map
3w9iA	3	0.9742	100	0.359	Contact Map
4mt1A	3	0.9484	100	0.362	Contact Map
4dx5A	3	0.9796	100	0.371	Contact Map
3aqpA	1	0.9308	100	0.476	Contact Map
4r86A	1	0.2849	100	0.803	Contact Map
3aqoA	1	0.2754	99.1	0.92	Contact Map
2l2tA	2	0.0597	48.7	0.977	Contact Map
2jwaA	2	0.0583	45.3	0.977	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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