GREMLIN Database
RECJ - Single-stranded-DNA-specific exonuclease RecJ
UniProt: O32044 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 786 (759)
Sequences: 626 (522)
Seq/√Len: 18.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
99_V200_V6.7431.00
154_A166_I5.4961.00
72_R81_E5.2821.00
154_A164_V5.2031.00
65_G68_E5.0661.00
84_M133_I4.8851.00
91_A224_I4.8161.00
349_A378_I4.6331.00
222_A240_I4.6151.00
200_V222_A4.3211.00
227_I275_V4.3201.00
498_I519_V4.2601.00
677_Y710_M4.0711.00
297_H306_E4.0621.00
409_P423_K3.8361.00
28_T469_E3.7801.00
348_V375_V3.7691.00
72_R163_D3.7641.00
509_I538_I3.6831.00
396_N399_E3.6131.00
84_M138_F3.6011.00
227_I241_A3.5961.00
187_Q190_C3.4621.00
102_H253_R3.4181.00
717_L741_S3.4091.00
127_E152_H3.3821.00
251_T256_L3.3641.00
67_K71_D3.3371.00
232_P479_L3.2841.00
546_E551_K3.2821.00
631_L641_L3.2471.00
131_R156_V3.2260.99
100_M206_L3.1970.99
155_K178_D3.0650.99
319_K322_Q3.0460.99
406_D433_R3.0350.99
395_F438_A2.9760.99
64_K189_G2.9430.99
301_S307_A2.8980.99
64_K187_Q2.8630.99
520_G523_K2.8480.99
456_V488_E2.8450.99
41_D45_S2.7950.98
127_E131_R2.7890.98
121_E129_A2.7890.98
58_Y235_D2.7630.98
204_F222_A2.7160.98
66_M209_A2.6880.98
65_G181_A2.6760.98
467_I553_P2.6540.98
72_R76_A2.6460.98
335_M350_K2.5890.97
117_D291_Q2.5650.97
127_E156_V2.5040.97
520_G557_I2.4590.96
176_L182_I2.4560.96
186_K195_K2.4530.96
190_C195_K2.4410.96
83_I109_A2.4230.96
114_Y129_A2.4020.96
220_D253_R2.3930.96
509_I518_C2.3890.96
77_I109_A2.3780.96
103_T207_A2.3710.96
32_A46_A2.3150.95
61_F209_A2.2980.95
82_K110_Q2.2780.95
95_T225_G2.2680.94
94_V295_A2.2380.94
57_F239_L2.2370.94
376_L385_A2.1770.93
337_E369_F2.1760.93
426_D429_D2.1610.93
348_V365_L2.1510.93
451_Q539_V2.1380.92
378_I385_A2.1150.92
486_L539_V2.0920.92
95_T283_L2.0870.91
130_F184_H2.0490.91
333_I337_E2.0290.90
715_F720_V2.0210.90
155_K159_E2.0190.90
389_A418_A2.0180.90
545_N554_Q1.9780.89
130_F272_E1.9670.89
133_I138_F1.9660.89
709_F747_K1.9350.88
100_M405_R1.9230.88
130_F141_I1.9230.88
72_R180_R1.8950.87
134_K160_L1.8910.87
81_E139_S1.8770.86
152_H156_V1.8670.86
57_F222_A1.8660.86
99_V198_A1.8540.86
453_V539_V1.8320.85
61_F66_M1.8220.85
468_A551_K1.8040.84
81_E163_D1.7970.84
98_S300_M1.7960.84
113_F296_V1.7940.84
674_F713_V1.7920.84
328_M357_V1.7890.83
117_D120_K1.7770.83
370_Y394_G1.7690.83
103_T107_L1.7660.83
484_H558_K1.7570.82
73_I142_I1.7470.82
184_H272_E1.7470.82
336_V346_I1.7440.82
204_F208_H1.7420.82
146_T241_A1.7350.81
60_P66_M1.7140.81
73_I140_L1.7050.80
184_H190_C1.6980.80
258_E311_A1.6920.80
114_Y121_E1.6860.80
282_R315_D1.6810.79
333_I369_F1.6680.79
97_T113_F1.6650.79
471_N474_S1.6590.78
77_I83_I1.6490.78
379_D382_K1.6410.78
407_I426_D1.6380.77
429_D432_S1.6370.77
70_A209_A1.6290.77
389_A397_L1.6280.77
730_V733_A1.6270.77
332_A353_W1.6260.77
431_R435_N1.6190.77
34_L480_N1.6150.76
402_S405_R1.6130.76
158_K180_R1.6000.76
171_E186_K1.5990.76
94_V283_L1.5980.76
255_G480_N1.5660.74
198_A225_G1.5630.74
35_L46_A1.5550.74
363_S366_V1.5480.73
222_A427_V1.5340.73
270_A274_T1.5310.72
423_K426_D1.5180.72
544_I551_K1.5070.71
19_K23_E1.5070.71
48_L235_D1.5060.71
365_L373_A1.5060.71
333_I368_R1.5050.71
75_Q79_Q1.4990.71
62_E193_P1.4970.71
85_I702_W1.4930.70
335_M348_V1.4930.70
6_M451_Q1.4920.70
436_E440_N1.4890.70
400_S437_I1.4830.70
104_L109_A1.4800.70
223_A227_I1.4670.69
715_F722_I1.4640.69
327_K331_E1.4630.69
324_M467_I1.4630.69
165_I426_D1.4610.69
286_V291_Q1.4560.68
141_I162_L1.4530.68
125_P130_F1.4490.68
65_G187_Q1.4450.68
149_A173_G1.4430.68
125_P184_H1.4390.68
506_K517_D1.4390.68
131_R135_E1.4380.67
592_S632_L1.4370.67
200_V225_G1.4320.67
395_F400_S1.4220.67
677_Y711_T1.4170.66
718_G730_V1.4090.66
89_Y123_Y1.4070.66
674_F710_M1.4050.66
85_I101_L1.4030.66
31_V469_E1.3970.65
76_A81_E1.3910.65
21_L25_L1.3890.65
86_Y280_A1.3890.65
428_P432_S1.3870.65
344_T439_D1.3860.65
262_L315_D1.3820.64
246_E249_R1.3770.64
69_A183_V1.3680.64
129_A363_S1.3680.64
345_A431_R1.3640.63
28_T31_V1.3640.63
276_G280_A1.3600.63
455_L485_V1.3550.63
249_R268_G1.3540.63
54_D243_L1.3430.62
462_I661_E1.3420.62
24_Q43_A1.3370.62
57_F204_F1.3320.61
343_Q346_I1.3320.61
429_D433_R1.3310.61
319_K382_K1.3290.61
121_E148_I1.3220.61
70_A73_I1.3160.60
95_T354_N1.3130.60
43_A47_R1.3070.60
198_A222_A1.3020.60
165_I180_R1.3010.60
422_L430_L1.3000.59
59_D66_M1.2980.59
630_V654_Y1.2950.59
173_G184_H1.2950.59
382_K424_A1.2950.59
141_I160_L1.2930.59
184_H187_Q1.2790.58
25_L46_A1.2790.58
121_E130_F1.2690.58
557_I560_A1.2690.58
27_I46_A1.2580.57
263_S282_R1.2580.57
200_V240_I1.2550.57
86_Y150_A1.2540.57
457_C485_V1.2540.57
427_V431_R1.2500.56
54_D239_L1.2400.56
94_V418_A1.2390.56
89_Y386_K1.2370.56
668_F747_K1.2370.56
69_A206_L1.2270.55
260_I267_I1.2250.55
207_A211_L1.2220.55
364_K522_N1.2200.54
344_T348_V1.2160.54
165_I735_K1.2150.54
40_F46_A1.2120.54
184_H274_T1.2080.54
130_F160_L1.2040.53
254_L258_E1.2030.53
407_I433_R1.2010.53
394_G415_P1.1990.53
464_V467_I1.1940.53
376_L420_M1.1930.53
437_I441_T1.1890.53
404_C437_I1.1870.52
207_A218_L1.1830.52
73_I206_L1.1820.52
289_I324_M1.1810.52
49_F480_N1.1790.52
95_T223_A1.1780.52
655_F677_Y1.1780.52
442_L446_D1.1760.52
694_S704_V1.1750.52
204_F240_I1.1740.52
219_L222_A1.1730.52
7_R449_P1.1730.52
405_R430_L1.1720.51
230_L478_M1.1690.51
142_I153_E1.1690.51
173_G416_M1.1670.51
260_I270_A1.1670.51
240_I532_P1.1640.51
307_A311_A1.1620.51
94_V292_A1.1610.51
349_A352_G1.1610.51
142_I165_I1.1550.50
521_F738_L1.1400.49
462_I587_K1.1380.49
154_A557_I1.1350.49
113_F297_H1.1340.49
345_A434_L1.1320.49
290_E346_I1.1290.49
366_V416_M1.1260.49
343_Q435_N1.1230.48
676_W700_K1.1200.48
345_A438_A1.1190.48
101_L300_M1.1180.48
374_I420_M1.1170.48
64_K190_C1.1170.48
325_V540_G1.1150.48
139_S453_V1.1140.48
27_I31_V1.1100.48
266_D269_E1.1040.47
541_E558_K1.1030.47
405_R411_F1.1000.47
403_E437_I1.0980.47
303_D306_E1.0960.47
567_L571_R1.0960.47
292_A418_A1.0930.47
345_A435_N1.0930.47
52_T242_T1.0900.46
113_F348_V1.0890.46
256_L260_I1.0880.46
432_S436_E1.0870.46
101_L111_V1.0860.46
8_W559_D1.0840.46
77_I107_L1.0820.46
134_K162_L1.0800.46
385_A427_V1.0790.46
345_A395_F1.0770.45
497_K528_E1.0770.45
349_A385_A1.0760.45
280_A369_F1.0740.45
260_I265_G1.0740.45
65_G111_V1.0720.45
352_G678_Y1.0700.45
717_L736_R1.0690.45
156_V160_L1.0690.45
89_Y194_F1.0670.45
365_L369_F1.0650.45
213_E217_E1.0630.45
57_F733_A1.0630.45
121_E186_K1.0600.44
484_H539_V1.0600.44
346_I369_F1.0570.44
255_G298_L1.0550.44
404_C408_L1.0490.44
518_C557_I1.0480.44
482_K541_E1.0480.44
119_F355_P1.0420.43
221_L253_R1.0420.43
240_I247_R1.0390.43
173_G300_M1.0390.43
165_I183_V1.0380.43
30_L466_S1.0370.43
231_V416_M1.0330.43
193_P235_D1.0320.43
745_Q749_Q1.0310.43
714_F738_L1.0310.43
241_A479_L1.0290.43
70_A206_L1.0290.43
375_V760_S1.0280.42
102_H302_E1.0260.42
182_I658_L1.0230.42
385_A422_L1.0220.42
89_Y192_Y1.0200.42
148_I186_K1.0190.42
637_S640_M1.0170.42
678_Y741_S1.0130.42
219_L255_G1.0130.42
373_A592_S1.0110.41
352_G378_I1.0100.41
18_V22_T1.0090.41
401_L408_L0.9980.41
241_A245_L0.9980.41
21_L46_A0.9970.41
117_D231_V0.9950.40
185_P202_V0.9950.40
760_S765_L0.9930.40
714_F719_F0.9920.40
15_Q33_S0.9900.40
283_L478_M0.9880.40
99_V222_A0.9870.40
62_E65_G0.9860.40
713_V738_L0.9850.40
290_E317_L0.9850.40
680_F684_R0.9840.40
22_T71_D0.9840.40
176_L179_V0.9820.40
517_D552_K0.9810.40
547_W571_R0.9800.40
347_V431_R0.9790.39
713_V717_L0.9780.39
588_R593_F0.9720.39
127_E153_E0.9720.39
339_Q431_R0.9650.39
427_V430_L0.9640.39
73_I519_V0.9620.38
70_A481_P0.9600.38
251_T301_S0.9590.38
384_I409_P0.9580.38
315_D319_K0.9550.38
94_V396_N0.9470.38
192_Y386_K0.9470.38
236_E295_A0.9450.37
221_L299_L0.9440.37
650_P653_I0.9430.37
96_S275_V0.9430.37
82_K139_S0.9420.37
184_H358_V0.9410.37
80_Q110_Q0.9400.37
200_V219_L0.9370.37
198_A226_T0.9370.37
657_F665_L0.9340.37
343_Q431_R0.9330.37
49_F238_R0.9310.37
593_F597_S0.9290.36
289_I295_A0.9280.36
714_F717_L0.9250.36
430_L434_L0.9250.36
713_V741_S0.9240.36
464_V553_P0.9230.36
325_V385_A0.9220.36
355_P415_P0.9220.36
65_G150_A0.9220.36
137_G157_A0.9210.36
286_V314_I0.9180.36
43_A46_A0.9170.36
460_E511_N0.9170.36
96_S542_M0.9140.36
358_V370_Y0.9130.36
196_E482_K0.9120.36
680_F687_F0.9110.35
714_F744_Y0.9110.35
121_E727_L0.9110.35
86_Y128_Q0.9090.35
286_V295_A0.9090.35
382_K492_L0.9070.35
590_I593_F0.9040.35
68_E180_R0.9020.35
163_D180_R0.9020.35
14_D672_D0.9010.35
487_V674_F0.8980.35
32_A36_V0.8960.35
487_V540_G0.8940.34
226_T241_A0.8940.34
496_R517_D0.8940.34
48_L56_D0.8920.34
63_M183_V0.8910.34
95_T396_N0.8900.34
392_I442_L0.8900.34
673_H706_T0.8900.34
301_S555_L0.8890.34
227_I383_G0.8840.34
200_V204_F0.8840.34
215_P540_G0.8820.34
35_L49_F0.8810.34
205_K208_H0.8800.34
425_E563_S0.8780.34
326_S330_D0.8780.34
91_A376_L0.8770.34
505_V547_W0.8760.33
146_T150_A0.8760.33
20_S24_Q0.8710.33
89_Y401_L0.8690.33
7_R150_A0.8670.33
680_F696_L0.8660.33
518_C555_L0.8640.33
103_T109_A0.8630.33
364_K519_V0.8590.33
54_D57_F0.8590.33
22_T25_L0.8580.32
374_I560_A0.8570.32
27_I574_R0.8570.32
540_G709_F0.8550.32
657_F669_P0.8550.32
264_G748_Q0.8540.32
157_A200_V0.8540.32
717_L727_L0.8530.32
537_S561_A0.8520.32
283_L299_L0.8520.32
346_I438_A0.8510.32
506_K554_Q0.8490.32
121_E369_F0.8480.32
21_L36_V0.8480.32
348_V465_E0.8480.32
348_V373_A0.8480.32
58_Y193_P0.8450.32
98_S296_V0.8430.32
265_G501_N0.8420.32
60_P209_A0.8400.31
636_P640_M0.8390.31
493_E510_R0.8380.31
347_V422_L0.8380.31
645_L648_K0.8360.31
30_L222_A0.8360.31
323_K327_K0.8360.31
99_V240_I0.8340.31
36_V46_A0.8310.31
107_L211_L0.8310.31
432_S646_E0.8310.31
709_F713_V0.8270.31
331_E392_I0.8270.31
286_V358_V0.8260.31
151_V173_G0.8260.31
75_Q338_Q0.8250.31
221_L720_V0.8240.31
351_A378_I0.8240.31
123_Y194_F0.8220.30
184_H751_M0.8220.30
196_E232_P0.8220.30
85_I104_L0.8210.30
232_P254_L0.8210.30
59_D62_E0.8210.30
115_I363_S0.8210.30
140_L163_D0.8200.30
363_S438_A0.8200.30
224_I375_V0.8200.30
230_L542_M0.8180.30
386_K635_P0.8170.30
671_R738_L0.8160.30
154_A300_M0.8150.30
367_D492_L0.8120.30
679_A683_K0.8110.30
135_E430_L0.8110.30
188_P192_Y0.8100.30
569_D572_G0.8080.30
173_G549_N0.8060.30
425_E752_E0.8050.30
106_K217_E0.8050.30
721_K728_S0.8050.30
98_S221_L0.8050.30
148_I634_P0.8030.29
95_T146_T0.8020.29
750_L753_L0.8020.29
248_L674_F0.7990.29
179_V182_I0.7990.29
228_A280_A0.7990.29
506_K545_N0.7980.29
245_L275_V0.7980.29
21_L27_I0.7970.29
365_L408_L0.7970.29
86_Y146_T0.7960.29
146_T184_H0.7950.29
117_D280_A0.7950.29
31_V187_Q0.7950.29
98_S682_L0.7950.29
420_M434_L0.7940.29
113_F280_A0.7940.29
253_R294_P0.7940.29
762_A765_L0.7930.29
142_I254_L0.7920.29
85_I334_E0.7920.29
192_Y236_E0.7910.29
66_M72_R0.7910.29
322_Q363_S0.7880.29
117_D548_N0.7870.29
400_S404_C0.7860.29
91_A146_T0.7860.29
68_E530_I0.7850.29
123_Y237_N0.7840.28
716_D741_S0.7840.28
283_L389_A0.7840.28
206_L279_L0.7820.28
238_R418_A0.7800.28
357_V431_R0.7800.28
144_V226_T0.7780.28
411_F459_V0.7780.28
85_I98_S0.7770.28
367_D401_L0.7760.28
158_K162_L0.7760.28
742_Q746_A0.7750.28
206_L752_E0.7740.28
416_M478_M0.7730.28
101_L105_Q0.7730.28
337_E368_R0.7720.28
109_A547_W0.7710.28
306_E309_E0.7710.28
365_L375_V0.7690.28
273_E286_V0.7670.28
125_P715_F0.7660.28
719_F725_G0.7640.27
164_V700_K0.7620.27
265_G278_Q0.7620.27
30_L50_L0.7620.27
538_I557_I0.7610.27
24_Q45_S0.7610.27
64_K100_M0.7600.27
261_K308_E0.7590.27
459_V511_N0.7590.27
45_S426_D0.7590.27
31_V35_L0.7590.27
231_V400_S0.7570.27
52_T57_F0.7570.27
204_F633_D0.7560.27
265_G274_T0.7560.27
237_N360_I0.7540.27
671_R678_Y0.7530.27
239_L243_L0.7520.27
310_L557_I0.7520.27
191_T279_L0.7520.27
355_P410_H0.7520.27
117_D554_Q0.7520.27
105_Q302_E0.7520.27
73_I83_I0.7500.27
73_I270_A0.7490.27
458_G461_D0.7480.27
462_I553_P0.7480.27
274_T278_Q0.7470.27
370_Y448_I0.7470.27
568_F571_R0.7470.27
232_P579_T0.7460.27
329_T553_P0.7420.26
210_L303_D0.7420.26
186_K370_Y0.7410.26
502_K542_M0.7400.26
283_L466_S0.7380.26
355_P377_G0.7370.26
363_S392_I0.7370.26
363_S669_P0.7370.26
37_K469_E0.7370.26
91_A141_I0.7370.26
17_K36_V0.7370.26
187_Q274_T0.7360.26
389_A443_T0.7340.26
228_A292_A0.7340.26
549_N733_A0.7330.26
589_A639_D0.7310.26
274_T397_L0.7310.26
231_V276_G0.7300.26
298_L310_L0.7300.26
275_V629_I0.7290.26
42_T465_E0.7280.26
222_A421_T0.7280.26
675_K679_A0.7260.26
336_V453_V0.7260.26
336_V345_A0.7260.26
187_Q195_K0.7220.25
63_M192_Y0.7220.25
53_K182_I0.7210.25
510_R513_S0.7200.25
260_I274_T0.7200.25
206_L692_H0.7200.25
97_T182_I0.7190.25
349_A377_G0.7170.25
613_I629_I0.7170.25
91_A230_L0.7160.25
200_V223_A0.7150.25
204_F322_Q0.7150.25
396_N644_L0.7130.25
198_A506_K0.7120.25
30_L760_S0.7110.25
334_E338_Q0.7110.25
70_A222_A0.7110.25
458_G468_A0.7080.25
63_M114_Y0.7070.25
65_G189_G0.7070.25
16_D452_E0.7060.25
283_L528_E0.7060.25
71_D488_E0.7060.25
457_C561_A0.7050.25
270_A653_I0.7050.25
371_R418_A0.7040.25
66_M76_A0.7040.25
329_T385_A0.7000.24
336_V354_N0.6980.24
346_I601_L0.6980.24
674_F759_Y0.6980.24
373_A378_I0.6980.24
198_A219_L0.6970.24
36_V245_L0.6960.24
184_H300_M0.6950.24
42_T46_A0.6950.24
400_S438_A0.6950.24
286_V300_M0.6940.24
146_T164_V0.6940.24
378_I678_Y0.6930.24
57_F245_L0.6920.24
327_K491_V0.6910.24
393_R452_E0.6900.24
529_G563_S0.6900.24
476_F559_D0.6890.24
159_E677_Y0.6880.24
521_F671_R0.6870.24
719_F733_A0.6870.24
164_V241_A0.6860.24
599_T603_T0.6860.24
593_F601_L0.6850.24
462_I574_R0.6850.24
33_S222_A0.6820.24
192_Y521_F0.6810.24
499_G506_K0.6790.23
72_R140_L0.6790.23
62_E66_M0.6780.23
85_I464_V0.6780.23
34_L212_G0.6770.23
142_I586_A0.6760.23
58_Y194_F0.6760.23
389_A392_I0.6760.23
627_A651_E0.6750.23
72_R171_E0.6750.23
126_N134_K0.6750.23
121_E286_V0.6750.23
331_E353_W0.6750.23
679_A682_L0.6740.23
461_D662_D0.6730.23
223_A280_A0.6730.23
154_A158_K0.6710.23
505_V524_G0.6710.23
641_L645_L0.6710.23
77_I304_S0.6710.23
681_L729_V0.6700.23
79_Q512_E0.6680.23
665_L754_D0.6680.23
57_F243_L0.6680.23
421_T518_C0.6670.23
239_L521_F0.6670.23
204_F540_G0.6670.23
304_S538_I0.6670.23
354_N683_K0.6660.23
385_A424_A0.6660.23
240_I275_V0.6650.23
468_A544_I0.6650.23
230_L416_M0.6650.23
172_P176_L0.6640.23
40_F45_S0.6640.23
158_K164_V0.6610.23
138_F516_L0.6610.23
234_H241_A0.6610.23
236_E386_K0.6600.23
224_I296_V0.6600.23
120_K218_L0.6590.23
325_V754_D0.6590.23
99_V225_G0.6580.22
346_I368_R0.6580.22
28_T466_S0.6580.22
273_E382_K0.6570.22
77_I103_T0.6570.22
129_A148_I0.6560.22
457_C716_D0.6560.22
343_Q348_V0.6560.22
227_I627_A0.6560.22
715_F721_K0.6560.22
129_A133_I0.6560.22
418_A678_Y0.6550.22
725_G754_D0.6550.22
422_L603_T0.6540.22
31_V352_G0.6540.22
150_A184_H0.6530.22
97_T141_I0.6530.22
172_P186_K0.6520.22
251_T530_I0.6520.22
112_D138_F0.6510.22
81_E519_V0.6500.22
272_E474_S0.6500.22
258_E307_A0.6500.22
18_V21_L0.6490.22
102_H221_L0.6490.22
686_A740_D0.6490.22
205_K236_E0.6480.22
669_P674_F0.6470.22
129_A132_S0.6470.22
192_Y325_V0.6460.22
206_L462_I0.6460.22
632_L636_P0.6460.22
157_A162_L0.6460.22
84_M402_S0.6460.22
31_V233_L0.6460.22
411_F501_N0.6460.22
248_L549_N0.6450.22
48_L142_I0.6440.22
364_K716_D0.6440.22
120_K290_E0.6430.22
265_G519_V0.6420.22
35_L38_R0.6420.22
162_L351_A0.6400.22
136_R425_E0.6400.22
110_Q348_V0.6390.22
220_D256_L0.6390.22
208_H241_A0.6380.22
49_F438_A0.6370.22
460_E538_I0.6370.22
121_E389_A0.6370.22
752_E756_K0.6370.22
370_Y418_A0.6360.22
442_L653_I0.6360.22
400_S700_K0.6350.21
283_L345_A0.6340.21
674_F678_Y0.6340.21
212_G221_L0.6340.21
593_F598_T0.6330.21
91_A325_V0.6330.21
317_L371_R0.6320.21
749_Q756_K0.6320.21
386_K540_G0.6310.21
119_F280_A0.6310.21
317_L354_N0.6310.21
490_A513_S0.6310.21
474_S480_N0.6310.21
490_A498_I0.6300.21
640_M643_R0.6300.21
17_K21_L0.6290.21
399_E426_D0.6290.21
73_I86_Y0.6280.21
121_E541_E0.6260.21
370_Y449_P0.6250.21
308_E492_L0.6240.21
392_I447_F0.6240.21
176_L519_V0.6230.21
85_I273_E0.6220.21
82_K399_E0.6210.21
27_I348_V0.6210.21
398_F418_A0.6210.21
104_L300_M0.6200.21
23_E245_L0.6200.21
367_D408_L0.6200.21
301_S306_E0.6200.21
125_P272_E0.6190.21
166_I214_L0.6190.21
130_F156_V0.6180.21
330_D334_E0.6180.21
50_L322_Q0.6180.21
263_S333_I0.6170.21
587_K594_K0.6160.21
94_V376_L0.6160.21
530_I630_V0.6150.21
184_H286_V0.6140.21
633_D765_L0.6120.21
492_L507_M0.6120.21
331_E335_M0.6120.21
94_V675_K0.6120.21
25_L85_I0.6110.20
407_I430_L0.6100.20
16_D152_H0.6100.20
52_T149_A0.6080.20
709_F765_L0.6070.20
406_D409_P0.6060.20
95_T111_V0.6060.20
461_D490_A0.6060.20
196_E231_V0.6060.20
82_K112_D0.6050.20
107_L427_V0.6050.20
148_I224_I0.6050.20
270_A399_E0.6040.20
20_S42_T0.6040.20
401_L654_Y0.6040.20
85_I115_I0.6030.20
421_T447_F0.6030.20
173_G332_A0.6030.20
139_S180_R0.6030.20
636_P754_D0.6030.20
546_E568_F0.6020.20
178_D217_E0.6020.20
331_E350_K0.6020.20
35_L322_Q0.6010.20
34_L455_L0.6010.20
85_I737_D0.6010.20
47_R51_H0.6000.20
457_C470_M0.6000.20
22_T460_E0.5990.20
279_L453_V0.5980.20
313_E317_L0.5980.20
391_S418_A0.5970.20
101_L113_F0.5970.20
376_L422_L0.5960.20
149_A493_E0.5960.20
488_E537_S0.5960.20
71_D302_E0.5960.20
144_V198_A0.5950.20
280_A536_I0.5950.20
358_V376_L0.5950.20
723_E745_Q0.5950.20
219_L265_G0.5950.20
594_K597_S0.5940.20
30_L457_C0.5940.20
88_D92_D0.5930.20
154_A524_G0.5930.20
706_T743_T0.5930.20
23_E686_A0.5920.20
94_V211_L0.5920.20
86_Y89_Y0.5920.20
699_H726_V0.5910.20
6_M146_T0.5910.20
204_F707_I0.5910.20
194_F235_D0.5910.20
437_I440_N0.5910.20
61_F486_L0.5900.20
719_F765_L0.5900.20
279_L313_E0.5900.20
739_T753_L0.5900.20
23_E493_E0.5890.20
69_A165_I0.5880.20
477_G483_P0.5880.20
405_R687_F0.5880.20
94_V207_A0.5870.20
44_E217_E0.5870.20
141_I157_A0.5870.20
270_A337_E0.5870.20
354_N396_N0.5870.20
86_Y223_A0.5840.19
42_T166_I0.5840.19
404_C433_R0.5830.19
239_L395_F0.5830.19
109_A207_A0.5830.19
102_H196_E0.5830.19
677_Y700_K0.5820.19
729_V751_M0.5820.19
107_L279_L0.5820.19
197_L324_M0.5810.19
113_F685_G0.5810.19
363_S395_F0.5810.19
225_G386_K0.5810.19
17_K41_D0.5800.19
227_I258_E0.5800.19
467_I544_I0.5800.19
285_A401_L0.5800.19
173_G570_L0.5800.19
158_K178_D0.5790.19
197_L205_K0.5790.19
123_Y192_Y0.5780.19
155_K555_L0.5780.19
396_N431_R0.5780.19
23_E85_I0.5770.19
148_I442_L0.5760.19
230_L325_V0.5760.19
155_K585_S0.5760.19
309_E640_M0.5760.19
80_Q304_S0.5750.19
59_D315_D0.5730.19
61_F212_G0.5730.19
125_P149_A0.5730.19
142_I427_V0.5730.19
506_K551_K0.5730.19
21_L629_I0.5730.19
305_F411_F0.5720.19
165_I654_Y0.5720.19
89_Y137_G0.5720.19
330_D338_Q0.5710.19
263_S283_L0.5710.19
86_Y154_A0.5710.19
122_G237_N0.5700.19
347_V445_E0.5690.19
463_T542_M0.5690.19
242_T327_K0.5680.19
154_A182_I0.5680.19
273_E364_K0.5680.19
759_Y762_A0.5670.19
74_K364_K0.5670.19
125_P314_I0.5670.19
299_L397_L0.5660.19
134_K139_S0.5660.19
102_H434_L0.5650.19
248_L557_I0.5650.19
227_I248_L0.5650.19
292_A379_D0.5650.19
173_G758_N0.5640.19
34_L520_G0.5630.19
421_T514_S0.5630.19
654_Y717_L0.5630.19
476_F554_Q0.5620.19
590_I632_L0.5620.19
78_S513_S0.5620.19
541_E551_K0.5620.19
681_L687_F0.5610.18
325_V498_I0.5610.18
119_F253_R0.5610.18
144_V717_L0.5590.18
245_L269_E0.5590.18
325_V376_L0.5590.18
517_D554_Q0.5590.18
45_S481_P0.5580.18
28_T265_G0.5580.18
42_T484_H0.5580.18
135_E620_K0.5580.18
369_F517_D0.5570.18
324_M512_E0.5570.18
121_E346_I0.5570.18
148_I385_A0.5570.18
174_P402_S0.5570.18
269_E295_A0.5560.18
101_L256_L0.5550.18
369_F727_L0.5550.18
148_I256_L0.5550.18
230_L329_T0.5550.18
106_K211_L0.5540.18
134_K220_D0.5540.18
89_Y179_V0.5540.18
269_E421_T0.5530.18
17_K484_H0.5530.18
26_H548_N0.5530.18
141_I180_R0.5530.18
184_H196_E0.5520.18
12_R324_M0.5520.18
202_V225_G0.5520.18
348_V429_D0.5520.18
248_L538_I0.5520.18
138_F741_S0.5510.18
14_D460_E0.5500.18
369_F708_N0.5500.18
247_R474_S0.5500.18
105_Q429_D0.5500.18
263_S757_L0.5500.18
714_F741_S0.5490.18
206_L570_L0.5490.18
95_T263_S0.5490.18
148_I727_L0.5490.18
258_E407_I0.5490.18
52_T370_Y0.5480.18
374_I411_F0.5480.18
224_I275_V0.5480.18
203_A207_A0.5480.18
519_V550_R0.5470.18
14_D85_I0.5470.18
220_D283_L0.5470.18
63_M73_I0.5470.18
422_L739_T0.5470.18
336_V341_L0.5460.18
150_A747_K0.5460.18
14_D239_L0.5450.18
602_Q612_V0.5450.18
667_T702_W0.5450.18
50_L204_F0.5450.18
155_K158_K0.5450.18
329_T333_I0.5450.18
590_I596_D0.5440.18
411_F496_R0.5440.18
280_A394_G0.5430.18
539_V698_K0.5430.18
200_V487_V0.5430.18
99_V679_A0.5420.18
370_Y389_A0.5420.18
719_F736_R0.5420.18
315_D557_I0.5410.18
557_I574_R0.5410.18
27_I32_A0.5410.18
330_D512_E0.5410.18
33_S461_D0.5410.18
100_M692_H0.5410.18
328_M336_V0.5400.18
120_K421_T0.5400.18
686_A728_S0.5400.18
447_F462_I0.5400.18
148_I702_W0.5400.18
631_L644_L0.5390.18
21_L335_M0.5390.18
104_L310_L0.5390.18
98_S629_I0.5380.18
191_T496_R0.5380.18
631_L634_P0.5380.18
149_A744_Y0.5380.18
172_P404_C0.5370.18
85_I111_V0.5370.18
512_E538_I0.5370.18
163_D171_E0.5360.18
230_L506_K0.5360.18
171_E349_A0.5350.18
166_I234_H0.5350.18
387_G540_G0.5350.18
85_I108_S0.5340.17
391_S478_M0.5340.17
154_A241_A0.5340.17
431_R445_E0.5340.17
234_H479_L0.5340.17
442_L445_E0.5340.17
530_I555_L0.5340.17
158_K183_V0.5330.17
171_E714_F0.5320.17
503_T507_M0.5320.17
440_N620_K0.5310.17
328_M354_N0.5310.17
276_G385_A0.5310.17
325_V719_F0.5300.17
104_L253_R0.5300.17
255_G259_L0.5300.17
154_A567_L0.5290.17
320_E323_K0.5290.17
311_A427_V0.5290.17
408_L430_L0.5290.17
289_I376_L0.5290.17
64_K183_V0.5280.17
152_H348_V0.5280.17
254_L434_L0.5280.17
490_A537_S0.5270.17
187_Q474_S0.5270.17
377_G385_A0.5270.17
361_V453_V0.5260.17
435_N506_K0.5260.17
283_L484_H0.5260.17
6_M375_V0.5260.17
84_M112_D0.5250.17
142_I538_I0.5250.17
409_P422_L0.5250.17
130_F146_T0.5250.17
241_A655_F0.5240.17
310_L411_F0.5240.17
91_A148_I0.5240.17
94_V230_L0.5230.17
220_D479_L0.5230.17
196_E227_I0.5230.17
103_T420_M0.5220.17
224_I754_D0.5220.17
58_Y62_E0.5220.17
677_Y687_F0.5210.17
320_E327_K0.5200.17
591_V594_K0.5200.17
171_E235_D0.5200.17
58_Y192_Y0.5190.17
87_G92_D0.5190.17
57_F144_V0.5190.17
220_D275_V0.5180.17
125_P722_I0.5180.17
126_N358_V0.5180.17
146_T317_L0.5170.17
291_Q423_K0.5170.17
165_I425_E0.5170.17
404_C454_D0.5170.17
94_V363_S0.5170.17
77_I280_A0.5170.17
130_F150_A0.5170.17
48_L69_A0.5160.17
282_R353_W0.5160.17
523_K557_I0.5160.17
342_D346_I0.5140.17
631_L657_F0.5140.17
166_I518_C0.5140.17
603_T612_V0.5140.17
510_R734_K0.5130.17
68_E411_F0.5130.17
117_D545_N0.5130.17
549_N747_K0.5130.17
34_L69_A0.5130.17
724_N746_A0.5130.17
540_G719_F0.5130.17
221_L245_L0.5130.17
333_I448_I0.5120.17
654_Y741_S0.5120.17
15_Q731_S0.5120.17
165_I418_A0.5120.17
723_E728_S0.5120.17
46_A348_V0.5110.17
8_W181_A0.5100.17
612_V637_S0.5100.17
157_A255_G0.5100.17
66_M81_E0.5100.17
231_V633_D0.5100.17
322_Q326_S0.5100.17
85_I221_L0.5100.17
136_R492_L0.5090.17
125_P540_G0.5090.17
361_V366_V0.5090.17
354_N410_H0.5080.17
34_L255_G0.5080.17
678_Y742_Q0.5080.17
87_G90_D0.5080.17
546_E566_Q0.5070.17
206_L459_V0.5070.17
265_G279_L0.5070.17
85_I455_L0.5070.17
279_L642_A0.5060.16
22_T83_I0.5060.16
109_A367_D0.5050.16
460_E630_V0.5040.16
389_A506_K0.5030.16
31_V498_I0.5030.16
192_Y226_T0.5030.16
157_A357_V0.5020.16
393_R416_M0.5020.16
421_T484_H0.5010.16
354_N546_E0.5010.16
369_F538_I0.5010.16
85_I649_A0.5000.16
262_L278_Q0.5000.16
144_V192_Y0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zxrA 1 0.7697 100 0.443 Contact Map
4ls9A 2 0.383 100 0.862 Contact Map
4py9A 2 0.3995 100 0.876 Contact Map
3devA 2 0.383 100 0.877 Contact Map
1wpnA 2 0.2252 99.7 0.935 Contact Map
2hawA 2 0.3715 98.8 0.959 Contact Map
1k20A 2 0.3613 98.5 0.963 Contact Map
4rpaA 3 0.355 98.5 0.963 Contact Map
2qb7A 1 0.388 97.7 0.97 Contact Map
2eb0A 2 0.3422 97.1 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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