SYDND - BACSU - GREMLIN Contacts

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SYDND - Aspartate--tRNA(Asp/Asn) ligase

UniProt:	O32038	Sequences: MFGRTYYCGDITEKAIGESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPDVSKEALAIAEGIRNEYVLDIQGKVVAREEGTVNPNLKTGAIEIHADGVNVLNAAKTPPFAISDQAEEVSEDVRLKHRYLDLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPILTGSTPEGARDYLVPSRVHEGEFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQPEFTQIDIEMSFMSQEDIMSLAEEMMAKVMRETKGEELQLPLPRMTYDEAMNKYGSDKPDTRFDMLLTDVSDIVKDTEFKVFSSAVANGGVVKAINVKGGAGDYSRKDIDALGAFAANYGAKGLAWVKVEADGVKGPIAKFFDEEKQSKLIEALDAAEGDLLLFGADQFEVVAASLGALRLKLGKERGLIDEKLFNFLWVIDWPLLEHDPEEGRFYAAHHPFTMPVREDLELIETAPEDMKAQAYDLVLNGYELGGGSIRIFEKDIQEKMFALLGFSPEEAAEQFGFLLEAFEYGAPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCLMTEAPGEVSDAQLDELHLSIKKKVKN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	592 (577)
Sequences:	3299 (1638)
Seq/√Len:	68.2

ECOLI - SYD
BACSU - SYDND

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
15_A	18_E	5.180	1.00
285_K	298_L	4.971	1.00
157_F	256_E	4.118	1.00
491_I	532_G	3.935	1.00
49_V	99_A	3.932	1.00
13_E	94_A	3.872	1.00
330_K	389_A	3.821	1.00
154_V	238_I	3.768	1.00
304_D	385_A	3.632	1.00
152_K	156_S	3.561	1.00
293_T	428_N	3.451	1.00
19_S	75_Q	3.268	1.00
109_K	525_E	3.249	1.00
468_A	471_D	3.094	1.00
263_R	269_E	3.050	1.00
73_D	103_N	2.992	1.00
75_Q	101_G	2.895	1.00
414_K	418_E	2.857	1.00
258_M	479_L	2.789	1.00
151_T	538_L	2.734	1.00
161_N	256_E	2.724	1.00
170_I	219_A	2.698	1.00
514_A	522_E	2.668	1.00
423_D	426_L	2.657	1.00
440_H	445_G	2.614	1.00
12_T	15_A	2.612	1.00
146_L	546_A	2.606	1.00
66_I	72_L	2.594	1.00
247_Q	475_Q	2.527	1.00
466_E	501_K	2.513	1.00
170_I	222_F	2.509	1.00
166_I	212_I	2.467	1.00
576_D	580_D	2.403	1.00
259_A	272_L	2.387	1.00
434_D	458_V	2.358	1.00
182_Y	563_A	2.346	1.00
22_L	97_I	2.337	1.00
80_A	86_V	2.307	1.00
464_L	471_D	2.304	1.00
441_D	444_E	2.302	1.00
326_A	386_L	2.262	1.00
21_T	75_Q	2.247	1.00
248_E	276_R	2.216	1.00
153_A	264_E	2.206	1.00
280_D	473_K	2.200	1.00
19_S	100_D	2.194	1.00
278_T	281_E	2.074	1.00
12_T	91_K	2.071	1.00
22_L	47_V	2.061	1.00
447_F	470_E	2.057	1.00
510_P	514_A	2.034	1.00
182_Y	188_V	2.033	1.00
286_Y	298_L	2.017	1.00
275_P	428_N	2.011	1.00
281_E	285_K	2.011	1.00
242_M	245_M	2.005	1.00
86_V	94_A	2.002	1.00
364_D	390_E	1.987	1.00
150_V	542_V	1.980	1.00
293_T	430_L	1.959	1.00
491_I	494_F	1.945	1.00
280_D	284_N	1.945	1.00
441_D	448_Y	1.922	1.00
16_I	80_A	1.916	1.00
245_M	250_I	1.914	1.00
278_T	434_D	1.910	1.00
152_K	159_D	1.899	1.00
19_S	77_K	1.894	1.00
500_E	510_P	1.888	1.00
288_S	409_G	1.875	1.00
79_V	98_H	1.868	1.00
363_A	390_E	1.868	1.00
459_R	475_Q	1.855	1.00
192_E	573_E	1.847	1.00
346_A	349_A	1.846	1.00
148_H	159_D	1.842	1.00
7_Y	44_T	1.810	1.00
159_D	216_Y	1.804	1.00
254_A	536_L	1.792	1.00
295_F	413_L	1.785	1.00
145_Q	164_L	1.780	1.00
23_K	73_D	1.778	1.00
375_D	378_K	1.772	1.00
338_R	342_D	1.765	1.00
329_V	332_G	1.754	1.00
183_L	574_V	1.749	1.00
190_E	583_H	1.745	1.00
240_I	534_I	1.745	1.00
49_V	74_I	1.742	1.00
77_K	100_D	1.730	1.00
565_C	568_T	1.730	1.00
44_T	47_V	1.729	1.00
299_L	325_K	1.726	1.00
144_M	212_I	1.723	1.00
260_K	264_E	1.717	1.00
11_I	95_I	1.716	1.00
305_I	385_A	1.702	1.00
277_M	430_L	1.695	1.00
250_I	532_G	1.689	1.00
326_A	394_L	1.685	0.99
13_E	16_I	1.682	0.99
466_E	504_A	1.680	0.99
342_D	345_G	1.665	0.99
548_R	553_D	1.660	0.99
202_L	519_F	1.659	0.99
47_V	97_I	1.635	0.99
429_F	481_L	1.630	0.99
504_A	510_P	1.629	0.99
401_F	405_A	1.625	0.99
143_T	548_R	1.621	0.99
509_S	512_E	1.618	0.99
153_A	260_K	1.617	0.99
160_E	260_K	1.616	0.99
34_G	53_P	1.615	0.99
580_D	587_K	1.614	0.99
11_I	15_A	1.610	0.99
348_A	411_L	1.610	0.99
78_V	97_I	1.601	0.99
508_F	513_A	1.578	0.99
165_D	216_Y	1.573	0.99
486_L	541_L	1.571	0.99
158_L	240_I	1.567	0.99
284_N	301_D	1.560	0.99
157_F	161_N	1.555	0.99
508_F	516_Q	1.552	0.99
481_L	486_L	1.525	0.99
238_I	538_L	1.522	0.99
262_M	545_L	1.515	0.99
302_V	382_L	1.512	0.99
26_V	72_L	1.508	0.99
7_Y	47_V	1.505	0.99
156_S	159_D	1.502	0.99
245_M	249_D	1.497	0.99
246_S	249_D	1.497	0.99
458_V	473_K	1.489	0.99
262_M	427_F	1.479	0.99
380_S	384_E	1.477	0.99
310_E	315_S	1.476	0.99
11_I	20_V	1.466	0.99
22_L	40_L	1.455	0.98
20_V	97_I	1.454	0.98
444_E	448_Y	1.453	0.98
381_K	384_E	1.451	0.98
282_A	288_S	1.450	0.98
277_M	432_V	1.448	0.98
44_T	213_E	1.447	0.98
439_E	450_A	1.440	0.98
461_D	473_K	1.438	0.98
106_N	528_A	1.427	0.98
513_A	521_L	1.424	0.98
135_L	210_S	1.407	0.98
154_V	538_L	1.401	0.98
145_Q	149_N	1.399	0.98
62_I	102_V	1.397	0.98
78_V	95_I	1.390	0.98
151_T	238_I	1.387	0.98
496_K	525_E	1.382	0.98
4_R	213_E	1.371	0.98
302_V	306_V	1.364	0.98
17_G	77_K	1.349	0.98
251_M	276_R	1.336	0.97
465_I	472_M	1.328	0.97
348_A	407_S	1.327	0.97
360_K	367_K	1.327	0.97
484_Y	550_N	1.327	0.97
496_K	500_E	1.321	0.97
245_M	491_I	1.318	0.97
437_L	502_M	1.313	0.97
274_L	429_F	1.312	0.97
73_D	105_L	1.312	0.97
325_K	405_A	1.303	0.97
425_K	547_G	1.303	0.97
240_I	254_A	1.300	0.97
247_Q	251_M	1.298	0.97
175_T	519_F	1.297	0.97
172_T	203_F	1.289	0.97
440_H	446_R	1.286	0.97
11_I	47_V	1.286	0.97
150_V	538_L	1.270	0.96
302_V	326_A	1.270	0.96
479_L	536_L	1.262	0.96
188_V	563_A	1.258	0.96
461_D	464_L	1.256	0.96
59_A	102_V	1.243	0.96
248_E	251_M	1.237	0.96
266_K	545_L	1.234	0.96
376_E	380_S	1.230	0.96
308_D	315_S	1.229	0.96
141_F	212_I	1.228	0.96
150_V	265_T	1.227	0.96
274_L	430_L	1.227	0.96
245_M	532_G	1.219	0.95
170_I	220_R	1.218	0.95
156_S	160_E	1.218	0.95
150_V	261_V	1.217	0.95
154_V	257_M	1.213	0.95
464_L	467_T	1.204	0.95
456_M	498_I	1.199	0.95
118_Q	139_A	1.195	0.95
7_Y	213_E	1.191	0.95
174_S	574_V	1.190	0.95
462_L	498_I	1.189	0.95
173_G	572_G	1.186	0.95
312_K	316_S	1.182	0.95
149_N	152_K	1.182	0.95
143_T	546_A	1.180	0.95
139_A	548_R	1.176	0.94
304_D	307_K	1.176	0.94
328_N	389_A	1.174	0.94
166_I	207_L	1.173	0.94
323_V	405_A	1.171	0.94
38_I	51_F	1.162	0.94
246_S	475_Q	1.155	0.94
13_E	80_A	1.154	0.94
399_D	403_V	1.154	0.94
378_K	381_K	1.152	0.94
138_P	142_Q	1.150	0.94
277_M	282_A	1.144	0.94
80_A	94_A	1.140	0.94
202_L	568_T	1.139	0.93
388_A	394_L	1.139	0.93
141_F	145_Q	1.139	0.93
339_K	343_A	1.132	0.93
329_V	419_R	1.127	0.93
29_R	67_R	1.124	0.93
495_E	498_I	1.120	0.93
82_E	85_T	1.118	0.93
361_V	388_A	1.117	0.93
161_N	253_L	1.113	0.93
328_N	394_L	1.110	0.93
512_E	516_Q	1.107	0.92
357_A	396_F	1.102	0.92
60_L	64_E	1.097	0.92
6_Y	18_E	1.093	0.92
6_Y	11_I	1.088	0.92
306_V	309_T	1.086	0.92
88_P	94_A	1.084	0.92
402_E	406_A	1.083	0.92
248_E	252_S	1.078	0.91
295_F	416_G	1.077	0.91
297_M	329_V	1.077	0.91
323_V	401_F	1.076	0.91
574_V	579_L	1.073	0.91
545_L	550_N	1.072	0.91
311_F	314_F	1.072	0.91
99_A	102_V	1.071	0.91
150_V	545_L	1.071	0.91
302_V	396_F	1.067	0.91
351_Y	410_A	1.065	0.91
153_A	265_T	1.060	0.91
376_E	379_Q	1.060	0.91
127_R	134_D	1.059	0.91
343_A	346_A	1.058	0.91
362_E	367_K	1.054	0.91
583_H	586_I	1.052	0.90
476_A	488_G	1.048	0.90
306_V	324_V	1.047	0.90
10_D	15_A	1.045	0.90
172_T	567_M	1.044	0.90
158_L	257_M	1.044	0.90
209_V	524_F	1.035	0.90
6_Y	15_A	1.034	0.90
414_K	417_K	1.034	0.90
52_N	79_V	1.031	0.90
153_A	261_V	1.031	0.90
328_N	386_L	1.030	0.89
207_L	556_A	1.030	0.89
189_H	563_A	1.026	0.89
174_S	578_Q	1.024	0.89
155_R	165_D	1.022	0.89
259_A	273_P	1.020	0.89
252_S	256_E	1.019	0.89
41_R	69_E	1.019	0.89
47_V	78_V	1.015	0.89
172_T	568_T	1.011	0.89
162_G	214_R	1.008	0.88
501_K	504_A	1.007	0.88
74_I	99_A	1.003	0.88
293_T	426_L	1.000	0.88
340_D	418_E	0.998	0.88
135_L	212_I	0.997	0.88
309_T	378_K	0.997	0.88
284_N	325_K	0.996	0.88
83_E	86_V	0.994	0.88
456_M	475_Q	0.992	0.88
560_T	564_S	0.992	0.88
61_A	64_E	0.992	0.88
12_T	94_A	0.987	0.87
328_N	387_D	0.987	0.87
576_D	587_K	0.985	0.87
139_A	143_T	0.985	0.87
65_G	107_A	0.984	0.87
542_V	546_A	0.982	0.87
296_D	327_I	0.981	0.87
383_I	388_A	0.980	0.87
10_D	44_T	0.975	0.87
452_H	490_S	0.974	0.87
242_M	250_I	0.972	0.87
209_V	528_A	0.970	0.86
351_Y	407_S	0.968	0.86
449_A	502_M	0.964	0.86
203_F	565_C	0.961	0.86
386_L	394_L	0.960	0.86
281_E	284_N	0.957	0.86
157_F	257_M	0.956	0.86
345_G	349_A	0.954	0.86
434_D	473_K	0.953	0.85
51_F	99_A	0.953	0.85
156_S	264_E	0.948	0.85
347_F	414_K	0.946	0.85
440_H	444_E	0.945	0.85
458_V	475_Q	0.943	0.85
153_A	156_S	0.943	0.85
62_I	65_G	0.936	0.84
250_I	491_I	0.936	0.84
9_G	12_T	0.934	0.84
188_V	194_Y	0.934	0.84
77_K	98_H	0.930	0.84
437_L	449_A	0.926	0.84
63_A	102_V	0.925	0.84
151_T	218_I	0.925	0.84
359_V	371_A	0.924	0.84
548_R	551_L	0.922	0.84
361_V	383_I	0.920	0.83
154_V	261_V	0.920	0.83
332_G	335_D	0.919	0.83
361_V	366_V	0.919	0.83
67_R	70_Y	0.918	0.83
550_N	553_D	0.916	0.83
577_A	581_E	0.914	0.83
560_T	566_L	0.913	0.83
261_V	265_T	0.912	0.83
285_K	299_L	0.911	0.83
161_N	214_R	0.911	0.83
203_F	568_T	0.910	0.83
61_A	65_G	0.909	0.83
444_E	577_A	0.906	0.82
309_T	315_S	0.902	0.82
317_A	322_G	0.902	0.82
29_R	36_I	0.902	0.82
116_S	120_E	0.900	0.82
146_L	150_V	0.898	0.82
7_Y	10_D	0.896	0.82
487_G	536_L	0.892	0.81
152_K	216_Y	0.892	0.81
399_D	404_V	0.891	0.81
10_D	47_V	0.890	0.81
146_L	265_T	0.889	0.81
40_L	72_L	0.889	0.81
51_F	102_V	0.888	0.81
258_M	536_L	0.886	0.81
354_K	399_D	0.884	0.81
149_N	159_D	0.883	0.81
129_K	569_E	0.880	0.81
575_S	578_Q	0.880	0.81
254_A	534_I	0.876	0.80
11_I	94_A	0.875	0.80
325_K	408_L	0.875	0.80
209_V	520_L	0.874	0.80
284_N	401_F	0.874	0.80
308_D	378_K	0.874	0.80
132_Y	567_M	0.873	0.80
417_K	422_I	0.870	0.80
43_R	145_Q	0.870	0.80
70_Y	104_V	0.870	0.80
115_I	133_L	0.869	0.80
514_A	525_E	0.866	0.80
422_I	426_L	0.866	0.80
450_A	474_A	0.863	0.79
377_E	380_S	0.863	0.79
435_W	450_A	0.863	0.79
7_Y	11_I	0.862	0.79
250_I	253_L	0.859	0.79
107_A	497_D	0.857	0.79
51_F	63_A	0.857	0.79
8_C	213_E	0.857	0.79
400_Q	403_V	0.855	0.79
167_E	220_R	0.855	0.79
275_P	278_T	0.854	0.79
375_D	379_Q	0.854	0.79
259_A	271_Q	0.854	0.79
117_D	120_E	0.853	0.78
462_L	501_K	0.853	0.78
263_R	267_G	0.853	0.78
300_T	386_L	0.850	0.78
365_G	390_E	0.846	0.78
158_L	216_Y	0.845	0.78
467_T	471_D	0.845	0.78
493_I	502_M	0.845	0.78
325_K	401_F	0.843	0.78
484_Y	544_L	0.842	0.78
278_T	433_I	0.841	0.78
281_E	298_L	0.841	0.78
347_F	351_Y	0.841	0.78
38_I	66_I	0.840	0.77
413_L	416_G	0.838	0.77
440_H	447_F	0.837	0.77
27_Q	116_S	0.834	0.77
242_M	249_D	0.834	0.77
328_N	388_A	0.832	0.77
332_G	336_Y	0.832	0.77
458_V	461_D	0.832	0.77
31_D	34_G	0.832	0.77
336_Y	419_R	0.831	0.77
417_K	424_E	0.831	0.77
148_H	152_K	0.830	0.77
329_V	336_Y	0.827	0.76
273_P	276_R	0.823	0.76
270_L	429_F	0.823	0.76
300_T	328_N	0.822	0.76
397_G	408_L	0.822	0.76
359_V	368_G	0.820	0.76
433_I	458_V	0.820	0.76
251_M	488_G	0.819	0.76
300_T	385_A	0.815	0.75
384_E	387_D	0.815	0.75
361_V	394_L	0.814	0.75
151_T	165_D	0.813	0.75
139_A	553_D	0.812	0.75
247_Q	458_V	0.809	0.75
362_E	365_G	0.808	0.75
144_M	166_I	0.808	0.75
40_L	49_V	0.808	0.75
312_K	315_S	0.806	0.74
413_L	417_K	0.802	0.74
400_Q	442_P	0.802	0.74
192_E	564_S	0.801	0.74
275_P	293_T	0.800	0.74
484_Y	543_M	0.800	0.74
460_E	473_K	0.797	0.74
420_G	424_E	0.795	0.73
82_E	86_V	0.794	0.73
174_S	195_A	0.793	0.73
462_L	466_E	0.790	0.73
166_I	210_S	0.787	0.73
299_L	405_A	0.786	0.73
52_N	98_H	0.784	0.72
306_V	382_L	0.781	0.72
11_I	22_L	0.781	0.72
353_A	356_L	0.780	0.72
51_F	66_I	0.776	0.72
27_Q	46_I	0.776	0.72
255_E	274_L	0.771	0.71
172_T	565_C	0.770	0.71
32_L	561_A	0.770	0.71
15_A	92_T	0.769	0.71
463_E	467_T	0.769	0.71
337_S	340_D	0.767	0.71
87_N	93_G	0.765	0.71
23_K	103_N	0.765	0.71
513_A	520_L	0.765	0.71
379_Q	383_I	0.764	0.70
323_V	404_V	0.764	0.70
171_L	184_V	0.764	0.70
230_D	484_Y	0.762	0.70
335_D	419_R	0.762	0.70
12_T	47_V	0.758	0.70
356_L	395_L	0.757	0.70
74_I	97_I	0.757	0.70
181_D	197_P	0.756	0.70
438_L	502_M	0.756	0.70
149_N	264_E	0.754	0.69
397_G	404_V	0.751	0.69
65_G	104_V	0.750	0.69
11_I	97_I	0.749	0.69
290_K	484_Y	0.748	0.69
302_V	305_I	0.748	0.69
347_F	411_L	0.747	0.69
156_S	260_K	0.746	0.69
583_H	587_K	0.746	0.69
258_M	541_L	0.745	0.69
44_T	162_G	0.742	0.68
15_A	47_V	0.741	0.68
5_T	21_T	0.741	0.68
32_L	35_L	0.741	0.68
152_K	165_D	0.739	0.68
415_L	419_R	0.738	0.68
113_F	122_V	0.738	0.68
192_E	572_G	0.737	0.68
469_P	472_M	0.737	0.68
123_S	126_V	0.736	0.68
6_Y	10_D	0.734	0.67
254_A	479_L	0.734	0.67
284_N	405_A	0.733	0.67
8_C	92_T	0.732	0.67
306_V	378_K	0.731	0.67
206_L	567_M	0.731	0.67
232_Q	487_G	0.730	0.67
357_A	370_I	0.729	0.67
488_G	535_A	0.728	0.67
277_M	285_K	0.727	0.67
380_S	383_I	0.727	0.67
258_M	270_L	0.727	0.67
290_K	409_G	0.727	0.67
409_G	413_L	0.727	0.67
580_D	585_S	0.726	0.67
141_F	166_I	0.723	0.66
486_L	536_L	0.723	0.66
262_M	429_F	0.722	0.66
306_V	315_S	0.721	0.66
464_L	472_M	0.721	0.66
452_H	476_A	0.720	0.66
189_H	583_H	0.719	0.66
39_D	90_L	0.718	0.66
194_Y	563_A	0.718	0.66
193_F	584_L	0.717	0.66
20_V	78_V	0.717	0.66
72_L	102_V	0.717	0.66
456_M	459_R	0.716	0.65
134_D	137_R	0.715	0.65
218_I	538_L	0.715	0.65
281_E	286_Y	0.714	0.65
479_L	487_G	0.713	0.65
164_L	212_I	0.712	0.65
383_I	386_L	0.712	0.65
423_D	428_N	0.711	0.65
577_A	580_D	0.710	0.65
261_V	545_L	0.710	0.65
132_Y	206_L	0.709	0.65
47_V	95_I	0.708	0.65
157_F	253_L	0.708	0.65
524_F	528_A	0.707	0.64
113_F	126_V	0.706	0.64
143_T	550_N	0.705	0.64
38_I	72_L	0.703	0.64
382_L	386_L	0.702	0.64
340_D	343_A	0.701	0.64
233_P	236_T	0.700	0.64
377_E	381_K	0.700	0.64
366_V	383_I	0.698	0.63
503_F	524_F	0.697	0.63
397_G	407_S	0.697	0.63
317_A	324_V	0.696	0.63
268_E	427_F	0.691	0.63
285_K	296_D	0.691	0.63
114_A	120_E	0.690	0.63
286_Y	296_D	0.690	0.63
328_N	332_G	0.690	0.63
87_N	90_L	0.689	0.62
128_L	566_L	0.689	0.62
21_T	73_D	0.688	0.62
36_I	67_R	0.686	0.62
259_A	269_E	0.684	0.62
58_E	61_A	0.683	0.62
117_D	139_A	0.683	0.62
258_M	486_L	0.681	0.62
283_M	288_S	0.680	0.61
148_H	216_Y	0.680	0.61
481_L	550_N	0.677	0.61
300_T	387_D	0.676	0.61
26_V	38_I	0.675	0.61
310_E	375_D	0.675	0.61
120_E	139_A	0.675	0.61
361_V	390_E	0.674	0.61
174_S	177_E	0.672	0.61
317_A	321_G	0.669	0.60
158_L	238_I	0.669	0.60
301_D	304_D	0.669	0.60
452_H	455_T	0.668	0.60
411_L	415_L	0.668	0.60
245_M	494_F	0.668	0.60
13_E	86_V	0.666	0.60
332_G	419_R	0.666	0.60
403_V	407_S	0.665	0.60
232_Q	499_Q	0.665	0.60
388_A	391_G	0.664	0.60
113_F	116_S	0.663	0.60
162_G	213_E	0.663	0.60
105_L	530_P	0.658	0.59
247_Q	433_I	0.658	0.59
271_Q	275_P	0.658	0.59
344_L	414_K	0.657	0.59
438_L	505_L	0.657	0.59
192_E	583_H	0.656	0.59
35_L	397_G	0.654	0.58
157_F	260_K	0.653	0.58
32_L	85_T	0.651	0.58
494_F	524_F	0.651	0.58
404_V	407_S	0.650	0.58
6_Y	47_V	0.650	0.58
44_T	145_Q	0.650	0.58
514_A	521_L	0.649	0.58
370_I	373_F	0.648	0.58
341_I	393_L	0.645	0.57
177_E	197_P	0.644	0.57
516_Q	575_S	0.644	0.57
307_K	385_A	0.643	0.57
240_I	253_L	0.641	0.57
12_T	16_I	0.640	0.57
255_E	276_R	0.638	0.57
339_K	342_D	0.637	0.56
190_E	586_I	0.637	0.56
463_E	466_E	0.637	0.56
333_A	360_K	0.636	0.56
511_E	515_E	0.635	0.56
66_I	102_V	0.635	0.56
182_Y	189_H	0.634	0.56
329_V	395_L	0.634	0.56
374_F	379_Q	0.634	0.56
172_T	570_A	0.633	0.56
167_E	236_T	0.633	0.56
182_Y	233_P	0.633	0.56
359_V	366_V	0.632	0.56
455_T	476_A	0.628	0.55
262_M	266_K	0.627	0.55
341_I	360_K	0.626	0.55
26_V	66_I	0.626	0.55
174_S	181_D	0.626	0.55
322_G	398_A	0.626	0.55
55_V	59_A	0.625	0.55
232_Q	490_S	0.625	0.55
293_T	296_D	0.624	0.55
202_L	520_L	0.622	0.55
51_F	72_L	0.622	0.55
265_T	277_M	0.621	0.55
576_D	585_S	0.620	0.54
347_F	350_N	0.620	0.54
341_I	395_L	0.620	0.54
403_V	406_A	0.619	0.54
36_I	60_L	0.618	0.54
430_L	479_L	0.618	0.54
328_N	392_D	0.618	0.54
475_Q	491_I	0.617	0.54
288_S	410_A	0.617	0.54
551_L	555_I	0.616	0.54
452_H	493_I	0.615	0.54
14_K	18_E	0.615	0.54
346_A	350_N	0.614	0.54
250_I	254_A	0.614	0.54
238_I	254_A	0.613	0.54
254_A	257_M	0.613	0.54
306_V	374_F	0.611	0.53
9_G	47_V	0.611	0.53
313_V	354_K	0.610	0.53
308_D	381_K	0.609	0.53
288_S	430_L	0.608	0.53
464_L	498_I	0.608	0.53
46_I	90_L	0.606	0.53
181_D	195_A	0.605	0.53
79_V	82_E	0.605	0.53
500_E	504_A	0.605	0.53
153_A	157_F	0.605	0.53
348_A	351_Y	0.604	0.53
219_A	475_Q	0.604	0.53
301_D	325_K	0.604	0.53
450_A	456_M	0.604	0.53
452_H	499_Q	0.604	0.53
126_V	129_K	0.603	0.52
500_E	514_A	0.602	0.52
423_D	547_G	0.601	0.52
420_G	423_D	0.601	0.52
238_I	257_M	0.601	0.52
128_L	560_T	0.600	0.52
329_V	415_L	0.600	0.52
32_L	39_D	0.597	0.52
284_N	323_V	0.597	0.52
366_V	379_Q	0.597	0.52
113_F	120_E	0.597	0.52
167_E	232_Q	0.593	0.51
199_S	499_Q	0.592	0.51
172_T	202_L	0.591	0.51
441_D	446_R	0.591	0.51
295_F	422_I	0.590	0.51
453_P	488_G	0.590	0.51
12_T	92_T	0.590	0.51
245_M	253_L	0.589	0.51
167_E	175_T	0.589	0.51
47_V	92_T	0.589	0.51
301_D	323_V	0.588	0.51
142_Q	149_N	0.588	0.51
359_V	367_K	0.588	0.51
303_S	323_V	0.587	0.51
220_R	238_I	0.586	0.50
165_D	203_F	0.586	0.50
158_L	534_I	0.586	0.50
107_A	495_E	0.585	0.50
189_H	564_S	0.585	0.50
463_E	501_K	0.585	0.50
43_R	164_L	0.584	0.50
381_K	385_A	0.584	0.50
232_Q	559_K	0.584	0.50
255_E	273_P	0.583	0.50
166_I	556_A	0.583	0.50
227_L	487_G	0.582	0.50
28_K	32_L	0.582	0.50
352_G	355_G	0.582	0.50
449_A	513_A	0.581	0.50
51_F	55_V	0.581	0.50
11_I	91_K	0.581	0.50
180_R	226_D	0.580	0.50
522_E	567_M	0.580	0.50
456_M	491_I	0.579	0.50
145_Q	212_I	0.578	0.49
406_A	410_A	0.578	0.49
484_Y	487_G	0.578	0.49
20_V	47_V	0.578	0.49
206_L	524_F	0.578	0.49
151_T	154_V	0.577	0.49
142_Q	145_Q	0.577	0.49
574_V	578_Q	0.575	0.49
62_I	103_N	0.575	0.49
337_S	343_A	0.574	0.49
440_H	470_E	0.573	0.49
257_M	260_K	0.573	0.49
247_Q	491_I	0.573	0.49
236_T	559_K	0.572	0.49
516_Q	584_L	0.572	0.49
453_P	506_L	0.571	0.49
463_E	471_D	0.571	0.49
344_L	395_L	0.571	0.49
310_E	378_K	0.570	0.48
464_L	469_P	0.570	0.48
15_A	95_I	0.570	0.48
251_M	479_L	0.569	0.48
266_K	547_G	0.568	0.48
282_A	432_V	0.567	0.48
406_A	409_G	0.567	0.48
359_V	396_F	0.567	0.48
455_T	499_Q	0.566	0.48
32_L	84_G	0.566	0.48
573_E	586_I	0.566	0.48
256_E	272_L	0.566	0.48
351_Y	406_A	0.565	0.48
450_A	476_A	0.563	0.48
71_V	108_A	0.563	0.48
338_R	372_K	0.563	0.48
564_S	569_E	0.562	0.48
108_A	111_P	0.562	0.48
309_T	382_L	0.562	0.48
6_Y	20_V	0.562	0.48
11_I	44_T	0.561	0.47
427_F	482_N	0.561	0.47
112_P	526_Y	0.561	0.47
449_A	488_G	0.560	0.47
32_L	358_W	0.559	0.47
240_I	536_L	0.557	0.47
500_E	525_E	0.556	0.47
437_L	469_P	0.555	0.47
333_A	393_L	0.555	0.47
317_A	398_A	0.555	0.47
25_W	244_F	0.554	0.47
120_E	137_R	0.554	0.47
233_P	559_K	0.553	0.46
522_E	526_Y	0.553	0.46
266_K	427_F	0.553	0.46
332_G	393_L	0.552	0.46
232_Q	236_T	0.549	0.46
274_L	479_L	0.548	0.46
230_D	552_R	0.547	0.46
464_L	501_K	0.547	0.46
422_I	425_K	0.547	0.46
315_S	378_K	0.547	0.46
249_D	491_I	0.545	0.46
12_T	95_I	0.545	0.46
521_L	525_E	0.545	0.46
195_A	517_F	0.544	0.45
132_Y	522_E	0.544	0.45
103_N	402_E	0.543	0.45
29_R	70_Y	0.543	0.45
284_N	299_L	0.542	0.45
81_R	93_G	0.542	0.45
59_A	66_I	0.541	0.45
251_M	254_A	0.540	0.45
142_Q	146_L	0.540	0.45
166_I	220_R	0.539	0.45
424_E	549_T	0.539	0.45
479_L	486_L	0.539	0.45
487_G	490_S	0.537	0.45
528_A	566_L	0.537	0.45
258_M	534_I	0.537	0.45
413_L	422_I	0.536	0.44
538_L	542_V	0.536	0.44
336_Y	340_D	0.536	0.44
520_L	528_A	0.536	0.44
488_G	534_I	0.535	0.44
18_E	77_K	0.535	0.44
175_T	232_Q	0.535	0.44
359_V	394_L	0.535	0.44
29_R	35_L	0.534	0.44
22_L	78_V	0.534	0.44
227_L	233_P	0.532	0.44
512_E	515_E	0.532	0.44
264_E	267_G	0.531	0.44
455_T	488_G	0.531	0.44
14_K	94_A	0.531	0.44
34_G	52_N	0.530	0.44
490_S	499_Q	0.529	0.44
199_S	232_Q	0.529	0.44
336_Y	506_L	0.529	0.44
203_F	570_A	0.529	0.44
260_K	263_R	0.528	0.44
520_L	524_F	0.528	0.44
270_L	275_P	0.527	0.43
306_V	379_Q	0.527	0.43
542_V	548_R	0.527	0.43
366_V	371_A	0.527	0.43
149_N	265_T	0.526	0.43
569_E	572_G	0.525	0.43
116_S	137_R	0.525	0.43
187_R	226_D	0.524	0.43
331_G	391_G	0.524	0.43
413_L	430_L	0.524	0.43
172_T	222_F	0.524	0.43
551_L	554_T	0.524	0.43
186_S	189_H	0.523	0.43
172_T	181_D	0.523	0.43
31_D	53_P	0.523	0.43
369_P	396_F	0.523	0.43
286_Y	405_A	0.523	0.43
341_I	345_G	0.522	0.43
145_Q	166_I	0.522	0.43
333_A	392_D	0.522	0.43
126_V	130_H	0.522	0.43
438_L	450_A	0.522	0.43
144_M	556_A	0.522	0.43
546_A	554_T	0.521	0.43
38_I	99_A	0.520	0.43
256_E	259_A	0.520	0.43
331_G	392_D	0.520	0.43
23_K	368_G	0.519	0.42
331_G	389_A	0.518	0.42
500_E	513_A	0.518	0.42
189_H	192_E	0.518	0.42
129_K	522_E	0.518	0.42
449_A	452_H	0.517	0.42
465_I	520_L	0.517	0.42
280_D	401_F	0.517	0.42
299_L	404_V	0.517	0.42
440_H	448_Y	0.517	0.42
314_F	357_A	0.516	0.42
330_K	387_D	0.515	0.42
236_T	499_Q	0.515	0.42
71_V	528_A	0.513	0.42
493_I	499_Q	0.513	0.42
202_L	513_A	0.513	0.42
369_P	570_A	0.513	0.42
39_D	46_I	0.513	0.42
305_I	378_K	0.513	0.42
548_R	554_T	0.512	0.42
71_V	106_N	0.512	0.42
297_M	421_L	0.511	0.42
508_F	519_F	0.510	0.41
66_I	70_Y	0.510	0.41
474_A	555_I	0.509	0.41
487_G	534_I	0.509	0.41
314_F	373_F	0.509	0.41
446_R	488_G	0.509	0.41
366_V	378_K	0.508	0.41
206_L	564_S	0.508	0.41
360_K	366_V	0.507	0.41
428_N	481_L	0.507	0.41
306_V	368_G	0.506	0.41
283_M	401_F	0.506	0.41
330_K	392_D	0.506	0.41
354_K	357_A	0.506	0.41
226_D	517_F	0.505	0.41
259_A	270_L	0.504	0.41
17_G	80_A	0.504	0.41
399_D	408_L	0.504	0.41
111_P	114_A	0.504	0.41
54_D	98_H	0.503	0.41
9_G	44_T	0.502	0.40
427_F	481_L	0.502	0.40
481_L	484_Y	0.500	0.40
10_D	91_K	0.500	0.40
429_F	486_L	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rmfA	2	0.9595	100	0.246	Contact Map
1l0wA	2	0.9696	100	0.273	Contact Map
1c0aA	1	0.978	100	0.274	Contact Map
4wj4A	2	0.9764	100	0.275	Contact Map
4ah6A	2	0.9679	100	0.344	Contact Map
4up7A	2	0.7838	100	0.522	Contact Map
3i7fA	2	0.7162	100	0.53	Contact Map
4ex5A	2	0.7314	100	0.54	Contact Map
1eovA	2	0.7551	100	0.54	Contact Map
1e1oA	2	0.7213	100	0.546	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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