GREMLIN Database
YOKG - SPBc2 prophage-derived pesticidal crystal protein-like YokG
UniProt: O32000 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 357 (318)
Sequences: 255 (210)
Seq/√Len: 11.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_C84_W4.5931.00
34_T84_W3.7380.99
80_L172_F3.3610.98
51_M84_W3.2250.97
246_Y250_Q3.1440.96
84_W307_W2.9190.95
243_M247_S2.8300.94
235_L239_I2.8260.94
307_W340_W2.7240.92
35_Q51_M2.6310.91
224_E227_K2.5700.90
301_E304_E2.5610.90
41_G81_C2.5540.89
169_G206_F2.5490.89
81_C169_G2.5290.89
31_W35_Q2.5260.89
329_L333_L2.4190.87
214_G218_E2.3690.85
134_I321_F2.3660.85
31_W51_M2.3050.84
252_F256_I2.2920.83
81_C202_L2.2770.83
237_G240_V2.2440.82
220_H224_E2.1710.80
84_W278_L2.1680.80
203_L273_V2.1550.79
24_G27_S2.1200.78
233_G239_I2.1120.78
207_M211_K2.0680.76
48_N52_K2.0130.74
146_R319_Q1.9920.74
84_W169_G1.9490.72
181_S185_V1.9390.71
48_N51_M1.9110.70
219_E310_I1.8890.69
213_L262_L1.8780.69
20_L24_G1.8650.68
51_M55_L1.8350.67
44_L307_W1.8150.66
77_Y296_S1.8020.66
27_S51_M1.7980.65
230_S240_V1.7780.64
317_L329_L1.7670.64
230_S245_E1.7640.64
310_I347_A1.7620.64
165_F310_I1.7480.63
213_L256_I1.7450.63
98_D154_S1.7330.62
81_C88_L1.6900.60
227_K237_G1.6880.60
111_N114_L1.6850.60
316_S347_A1.6770.60
169_G307_W1.6760.60
154_S216_S1.6750.60
314_F317_L1.6730.60
103_G336_A1.6710.59
88_L162_L1.6640.59
26_I47_S1.6440.58
69_K272_V1.6270.57
31_W38_I1.6130.57
333_L336_A1.6070.56
70_L115_Q1.5710.55
241_S245_E1.5620.54
220_H245_E1.5520.54
24_G35_Q1.5410.53
102_V300_I1.5360.53
28_T47_S1.5240.52
37_N45_P1.5170.52
234_P238_Y1.4870.50
65_Q317_L1.4860.50
226_V240_V1.4800.50
279_F286_L1.4770.50
114_L117_G1.4770.50
225_K229_S1.4380.48
89_L329_L1.4290.48
39_L43_G1.4090.47
148_L307_W1.4080.47
51_M350_F1.4000.46
253_K257_D1.3900.46
237_G248_D1.3840.45
33_K53_T1.3700.45
155_M228_F1.3570.44
44_L340_W1.3530.44
197_S315_Y1.3370.43
80_L162_L1.3350.43
233_G340_W1.3270.43
140_V228_F1.3200.42
158_V324_E1.3200.42
101_N253_K1.3200.42
214_G257_D1.3160.42
301_E305_G1.3120.42
220_H256_I1.3010.41
222_I226_V1.2880.41
231_E234_P1.2870.41
293_A300_I1.2850.41
63_I137_F1.2830.40
228_F241_S1.2760.40
227_K248_D1.2750.40
160_N167_Q1.2700.40
279_F321_F1.2670.40
317_L350_F1.2630.39
145_M315_Y1.2620.39
84_W88_L1.2610.39
252_F295_R1.2590.39
96_A102_V1.2450.39
97_N351_V1.2370.38
137_F350_F1.2120.37
114_L144_L1.2070.37
205_I342_A1.2030.37
84_W151_N1.2020.37
37_N165_F1.1990.36
245_E249_V1.1950.36
84_W317_L1.1930.36
47_S50_E1.1920.36
34_T261_N1.1870.36
216_S219_E1.1860.36
236_I241_S1.1800.36
260_Q263_N1.1760.35
234_P282_I1.1750.35
240_V248_D1.1700.35
27_S84_W1.1680.35
265_V269_V1.1660.35
296_S340_W1.1510.34
288_N292_Q1.1480.34
123_T211_K1.1430.34
94_K243_M1.1410.34
27_S30_Y1.1400.34
26_I71_Y1.1350.34
165_F205_I1.1350.34
185_V243_M1.1240.33
141_C202_L1.1080.32
165_F206_F1.1070.32
213_L220_H1.1050.32
27_S333_L1.1000.32
34_T330_S1.0930.32
37_N80_L1.0920.32
245_E248_D1.0900.32
76_E93_N1.0890.32
23_D31_W1.0890.32
25_L56_N1.0840.31
91_C125_S1.0840.31
264_G268_Q1.0810.31
118_L122_T1.0720.31
290_I301_E1.0680.31
27_S317_L1.0580.30
50_E162_L1.0530.30
70_L74_Y1.0510.30
224_E249_V1.0470.30
102_V106_T1.0430.30
189_L333_L1.0430.30
25_L59_K1.0290.29
103_G112_E1.0250.29
204_N207_M1.0230.29
143_I268_Q1.0140.28
102_V329_L1.0110.28
269_V336_A1.0100.28
51_M130_R1.0100.28
80_L224_E1.0060.28
190_D257_D1.0010.28
236_I312_N0.9990.28
95_M321_F0.9980.28
24_G31_W0.9970.28
150_E268_Q0.9960.28
204_N273_V0.9960.28
66_D118_L0.9920.28
311_A344_A0.9880.27
252_F303_T0.9840.27
79_K250_Q0.9770.27
80_L220_H0.9740.27
298_E327_N0.9740.27
121_I329_L0.9700.27
244_L247_S0.9700.27
254_Q265_V0.9670.27
138_H322_E0.9660.27
156_K318_A0.9650.26
36_A39_L0.9550.26
213_L279_F0.9520.26
261_N322_E0.9460.26
234_P243_M0.9440.26
142_L194_N0.9410.26
120_A160_N0.9380.25
202_L248_D0.9360.25
165_F213_L0.9350.25
96_A287_H0.9340.25
92_V317_L0.9320.25
153_Q237_G0.9290.25
27_S329_L0.9280.25
38_I42_T0.9250.25
48_N56_N0.9220.25
335_N349_E0.9220.25
46_V279_F0.9190.25
72_D153_Q0.9160.25
74_Y228_F0.9160.25
84_W350_F0.9160.25
111_N324_E0.9090.24
165_F192_Q0.9060.24
99_I145_M0.9020.24
51_M67_F0.9010.24
237_G241_S0.9000.24
49_D345_N0.8970.24
34_T51_M0.8970.24
133_A148_L0.8960.24
133_A144_L0.8950.24
305_G313_Q0.8940.24
166_L299_F0.8900.24
34_T81_C0.8890.24
93_N314_F0.8880.24
41_G77_Y0.8870.24
25_L52_K0.8860.24
106_T216_S0.8770.23
231_E238_Y0.8740.23
35_Q89_L0.8740.23
191_S263_N0.8730.23
166_L294_E0.8720.23
74_Y307_W0.8680.23
37_N220_H0.8620.23
35_Q54_Y0.8600.23
118_L350_F0.8590.23
38_I60_N0.8590.23
95_M98_D0.8590.23
29_G33_K0.8560.22
224_E256_I0.8560.22
51_M81_C0.8550.22
51_M307_W0.8520.22
276_L321_F0.8510.22
78_K224_E0.8470.22
169_G336_A0.8390.22
215_E286_L0.8380.22
317_L343_V0.8360.22
264_G316_S0.8340.22
27_S43_G0.8280.22
48_N264_G0.8280.22
202_L226_V0.8270.21
80_L83_W0.8260.21
153_Q157_D0.8230.21
31_W41_G0.8210.21
254_Q257_D0.8210.21
168_G310_I0.8180.21
84_W106_T0.8110.21
41_G51_M0.8090.21
237_G244_L0.8050.21
296_S351_V0.8050.21
78_K281_G0.8040.21
93_N236_I0.8030.21
294_E297_L0.8020.21
124_A310_I0.8000.21
118_L236_I0.7960.20
206_F265_V0.7940.20
34_T99_I0.7920.20
141_C206_F0.7840.20
182_F185_V0.7820.20
232_L237_G0.7800.20
179_N205_I0.7760.20
141_C345_N0.7750.20
27_S133_A0.7730.20
57_L73_V0.7690.20
324_E350_F0.7670.20
111_N321_F0.7670.20
68_Q293_A0.7670.20
287_H309_S0.7660.20
32_A43_G0.7660.20
115_Q197_S0.7600.19
137_F310_I0.7600.19
315_Y318_A0.7590.19
80_L300_I0.7580.19
20_L27_S0.7580.19
41_G84_W0.7560.19
32_A74_Y0.7530.19
165_F261_N0.7520.19
142_L266_D0.7500.19
166_L242_E0.7490.19
145_M287_H0.7480.19
239_I243_M0.7460.19
233_G307_W0.7440.19
150_E322_E0.7430.19
161_L255_R0.7430.19
144_L263_N0.7410.19
144_L336_A0.7400.19
63_I236_I0.7380.19
263_N341_E0.7360.19
228_F242_E0.7360.19
313_Q329_L0.7360.19
70_L307_W0.7310.18
227_K253_K0.7310.18
114_L118_L0.7300.18
130_R321_F0.7290.18
155_M311_A0.7230.18
96_A343_V0.7230.18
100_Y217_L0.7220.18
194_N347_A0.7200.18
271_L289_V0.7190.18
34_T265_V0.7190.18
141_C278_L0.7190.18
102_V262_L0.7180.18
254_Q342_A0.7160.18
95_M102_V0.7160.18
249_V303_T0.7140.18
81_C245_E0.7140.18
97_N153_Q0.7140.18
44_L74_Y0.7140.18
129_D133_A0.7120.18
33_K46_V0.7110.18
153_Q205_I0.7100.18
194_N316_S0.7080.18
93_N240_V0.7070.18
192_Q313_Q0.7040.18
90_S102_V0.7030.18
26_I333_L0.7010.18
121_I124_A0.7000.18
40_T43_G0.7000.18
76_E286_L0.6990.18
249_V347_A0.6980.17
80_L335_N0.6980.17
287_H316_S0.6970.17
31_W350_F0.6960.17
167_Q319_Q0.6910.17
123_T143_I0.6900.17
31_W307_W0.6880.17
156_K270_A0.6860.17
220_H249_V0.6860.17
169_G228_F0.6860.17
162_L255_R0.6850.17
27_S351_V0.6830.17
103_G206_F0.6810.17
236_I239_I0.6710.17
70_L90_S0.6710.17
257_D260_Q0.6700.17
300_I313_Q0.6690.17
291_Y333_L0.6670.17
310_I350_F0.6670.17
91_C280_H0.6650.17
96_A310_I0.6630.16
206_F213_L0.6620.16
112_E123_T0.6620.16
112_E227_K0.6610.16
243_M252_F0.6600.16
31_W299_F0.6600.16
149_D267_A0.6600.16
311_A334_D0.6590.16
274_K314_F0.6580.16
81_C246_Y0.6570.16
26_I269_V0.6570.16
72_D101_N0.6560.16
84_W210_K0.6510.16
112_E261_N0.6500.16
231_E312_N0.6480.16
28_T54_Y0.6480.16
67_F84_W0.6460.16
161_L246_Y0.6460.16
24_G185_V0.6450.16
64_P68_Q0.6440.16
297_L305_G0.6420.16
215_E218_E0.6400.16
204_N327_N0.6370.16
30_Y33_K0.6360.16
35_Q336_A0.6340.16
95_M203_L0.6340.16
73_V210_K0.6320.16
243_M302_Q0.6300.16
285_D310_I0.6300.16
315_Y319_Q0.6280.16
100_Y348_K0.6270.16
315_Y334_D0.6250.15
231_E242_E0.6230.15
223_N226_V0.6200.15
35_Q333_L0.6200.15
61_V272_V0.6200.15
88_L140_V0.6170.15
136_D156_K0.6160.15
235_L312_N0.6160.15
80_L157_D0.6160.15
186_M301_E0.6130.15
217_L221_E0.6120.15
109_L157_D0.6090.15
21_G188_Y0.6080.15
236_I240_V0.6050.15
37_N331_T0.5990.15
89_L350_F0.5980.15
297_L318_A0.5970.15
31_W80_L0.5950.15
114_L310_I0.5950.15
81_C307_W0.5920.15
88_L170_N0.5910.15
67_F350_F0.5900.15
202_L210_K0.5890.15
51_M89_L0.5890.15
32_A48_N0.5860.14
73_V89_L0.5850.14
155_M296_S0.5820.14
123_T342_A0.5810.14
95_M350_F0.5800.14
129_D321_F0.5800.14
231_E249_V0.5780.14
186_M269_V0.5780.14
125_S187_T0.5770.14
27_S32_A0.5760.14
234_P242_E0.5750.14
263_N349_E0.5740.14
131_Q134_I0.5740.14
214_G260_Q0.5730.14
20_L38_I0.5720.14
20_L96_A0.5710.14
133_A336_A0.5700.14
147_E260_Q0.5690.14
83_W186_M0.5670.14
72_D257_D0.5670.14
207_M231_E0.5670.14
118_L137_F0.5670.14
42_T166_L0.5640.14
299_F305_G0.5590.14
342_A349_E0.5590.14
24_G133_A0.5590.14
278_L293_A0.5590.14
69_K207_M0.5580.14
31_W34_T0.5580.14
118_L223_N0.5570.14
92_V220_H0.5540.14
110_I310_I0.5530.14
37_N248_D0.5520.14
262_L269_V0.5520.14
230_S235_L0.5490.14
113_A116_P0.5490.14
44_L329_L0.5480.14
51_M85_L0.5480.14
25_L273_V0.5460.14
222_I247_S0.5450.14
153_Q160_N0.5440.13
61_V275_V0.5440.13
217_L223_N0.5420.13
45_P202_L0.5410.13
220_H242_E0.5410.13
146_R323_N0.5390.13
150_E211_K0.5390.13
25_L28_T0.5380.13
153_Q254_Q0.5380.13
34_T53_T0.5380.13
138_H339_T0.5370.13
276_L302_Q0.5360.13
70_L242_E0.5360.13
35_Q148_L0.5320.13
203_L280_H0.5300.13
149_D263_N0.5300.13
144_L158_V0.5280.13
40_T162_L0.5280.13
41_G210_K0.5280.13
29_G267_A0.5280.13
123_T329_L0.5270.13
164_S168_G0.5270.13
294_E319_Q0.5270.13
112_E347_A0.5250.13
88_L276_L0.5240.13
172_F210_K0.5220.13
31_W74_Y0.5210.13
88_L299_F0.5210.13
152_Q282_I0.5200.13
51_M54_Y0.5190.13
137_F284_I0.5180.13
93_N313_Q0.5170.13
162_L210_K0.5150.13
74_Y299_F0.5140.13
78_K310_I0.5140.13
67_F339_T0.5140.13
59_K167_Q0.5110.13
77_Y347_A0.5090.13
252_F258_N0.5080.13
94_K218_E0.5080.13
74_Y103_G0.5080.13
206_F263_N0.5080.13
134_I205_I0.5050.13
317_L342_A0.5040.13
149_D338_A0.5040.13
243_M246_Y0.5020.13
22_R48_N0.5020.13
221_E228_F0.5010.13
102_V162_L0.5010.13
57_L158_V0.5000.12
204_N208_Q0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4k1pA 1 0.888 100 0.467 Contact Map
2nrjA 1 0.8824 100 0.48 Contact Map
4linA 5 0.6527 90.8 0.928 Contact Map
4uxvA 1 0.8347 81 0.938 Contact Map
4cgkA 3 0.549 68.6 0.944 Contact Map
3vkgA 2 0.8515 62.3 0.946 Contact Map
4rsiB 1 0.5154 43.3 0.952 Contact Map
4q4gX 1 0.0112 37.8 0.954 Contact Map
2a01A 1 0.6387 35.8 0.954 Contact Map
1i84S 2 0.3866 35.2 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.