BLYA - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

BLYA - N-acetylmuramoyl-L-alanine amidase BlyA

UniProt:	O31982	Sequences: MSVFTNSYIPVNKYTRPGLKLQGVKKCVLHYTANPGAGADNHRRYFSNAQVYASAHIFVDKAEAICIIPLNEVAYHANDIQQRDSAGNPYRGVAALKPNANFLSIGVEMCLEKDGSFHSDTVERTEDVFVELCNKFGLDPIDDIVRHYDITHKNCPAPWVSNSQKFVDFKNRVKAKMSGKSVSKASPTKPTTSSPSSSSAVSGSLKSKVDGLRFYSKPSWEDKDVVGTVNKGIGFPTVVEKVKVGSAYQYKVKNSKGTTYYITASDKYVDVTGSVKTSSSAPKTTSTSSSSSSIKSVGKIKIVGVSSAAIVMDKPDRNSSKNIGTVKLGSTISISGSVKGKNNSNGYWEVIYKGKRGYISGQFGSTI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	367 (327)
Sequences:	394 (297)
Seq/√Len:	16.4

BACSU - BLYA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
68_I	74_A	5.619	1.00
59_V	107_V	5.527	1.00
56_H	70_L	3.962	1.00
293_S	297_V	3.806	1.00
293_S	299_K	3.359	0.99
297_V	300_I	3.162	0.99
293_S	300_I	3.088	0.99
76_H	106_G	3.023	0.99
345_N	360_S	2.755	0.97
34_N	41_N	2.754	0.97
345_N	362_Q	2.742	0.97
293_S	301_K	2.736	0.97
34_N	42_H	2.710	0.97
293_S	296_S	2.547	0.96
300_I	303_V	2.546	0.96
297_V	301_K	2.501	0.95
309_A	316_D	2.497	0.95
324_G	330_S	2.485	0.95
288_S	291_S	2.454	0.95
293_S	303_V	2.437	0.94
293_S	302_I	2.371	0.93
58_F	67_I	2.350	0.93
316_D	320_S	2.325	0.93
28_V	150_I	2.288	0.92
310_I	316_D	2.249	0.91
299_K	303_V	2.220	0.91
297_V	302_I	2.183	0.90
287_T	290_S	2.183	0.90
299_K	302_I	2.087	0.88
125_T	169_F	2.031	0.87
16_R	19_L	1.992	0.85
219_S	222_D	1.989	0.85
287_T	291_S	1.985	0.85
8_Y	17_P	1.917	0.83
296_S	300_I	1.915	0.83
226_V	269_V	1.915	0.83
53_A	74_A	1.906	0.83
54_S	68_I	1.896	0.82
310_I	313_D	1.890	0.82
297_V	303_V	1.889	0.82
288_S	293_S	1.889	0.82
300_I	304_G	1.885	0.82
55_A	67_I	1.866	0.81
46_F	55_A	1.841	0.80
310_I	314_K	1.802	0.79
54_S	74_A	1.799	0.79
305_V	308_A	1.792	0.79
324_G	328_L	1.768	0.78
34_N	58_F	1.749	0.77
231_K	239_V	1.705	0.75
311_V	316_D	1.703	0.75
330_S	333_S	1.686	0.74
304_G	308_A	1.680	0.74
324_G	329_G	1.669	0.73
8_Y	12_N	1.665	0.73
188_T	191_T	1.659	0.73
40_D	44_R	1.650	0.72
320_S	323_I	1.648	0.72
311_V	317_R	1.610	0.70
188_T	193_S	1.606	0.70
288_S	297_V	1.589	0.69
29_L	105_I	1.585	0.69
55_A	58_F	1.567	0.68
321_K	324_G	1.566	0.68
323_I	329_G	1.544	0.67
39_A	60_D	1.534	0.67
44_R	250_Y	1.520	0.66
320_S	330_S	1.504	0.65
326_V	332_I	1.501	0.65
309_A	313_D	1.492	0.64
109_M	125_T	1.478	0.64
323_I	330_S	1.478	0.64
306_S	315_P	1.457	0.62
311_V	314_K	1.440	0.62
296_S	299_K	1.423	0.61
330_S	336_G	1.411	0.60
322_N	329_G	1.404	0.60
348_W	361_G	1.384	0.58
327_K	330_S	1.374	0.58
306_S	309_A	1.373	0.58
309_A	324_G	1.361	0.57
320_S	331_T	1.349	0.56
46_F	58_F	1.336	0.56
313_D	316_D	1.333	0.55
25_K	103_L	1.331	0.55
217_K	223_K	1.327	0.55
219_S	223_K	1.314	0.54
326_V	330_S	1.313	0.54
309_A	320_S	1.306	0.54
307_S	310_I	1.300	0.54
74_A	106_G	1.297	0.53
291_S	300_I	1.289	0.53
314_K	326_V	1.285	0.53
167_V	246_S	1.277	0.52
78_N	101_N	1.274	0.52
329_G	336_G	1.274	0.52
293_S	304_G	1.267	0.52
215_Y	223_K	1.260	0.51
53_A	68_I	1.252	0.51
308_A	311_V	1.232	0.50
119_S	168_D	1.228	0.49
18_G	25_K	1.218	0.49
237_T	241_K	1.217	0.49
309_A	312_M	1.214	0.48
60_D	110_C	1.214	0.48
30_H	108_E	1.214	0.48
296_S	302_I	1.212	0.48
320_S	324_G	1.206	0.48
26_K	138_L	1.203	0.48
205_L	209_V	1.202	0.48
30_H	147_H	1.196	0.47
9_I	12_N	1.183	0.47
56_H	59_V	1.180	0.46
309_A	330_S	1.175	0.46
237_T	240_E	1.173	0.46
309_A	315_P	1.172	0.46
352_Y	357_G	1.170	0.46
126_E	172_R	1.160	0.45
311_V	315_P	1.160	0.45
9_I	17_P	1.158	0.45
149_D	351_I	1.158	0.45
310_I	315_P	1.152	0.45
26_K	104_S	1.149	0.45
58_F	107_V	1.146	0.45
210_D	213_R	1.142	0.44
27_C	105_I	1.139	0.44
321_K	330_S	1.135	0.44
301_K	329_G	1.134	0.44
301_K	304_G	1.133	0.44
323_I	336_G	1.129	0.44
314_K	335_S	1.128	0.43
296_S	303_V	1.125	0.43
8_Y	16_R	1.125	0.43
274_S	279_S	1.124	0.43
109_M	121_T	1.116	0.43
195_P	198_S	1.115	0.43
330_S	335_S	1.112	0.43
289_S	296_S	1.112	0.43
307_S	313_D	1.106	0.42
46_F	67_I	1.101	0.42
59_V	63_E	1.093	0.41
35_P	41_N	1.091	0.41
31_Y	106_G	1.084	0.41
313_D	335_S	1.074	0.40
15_T	18_G	1.072	0.40
314_K	320_S	1.069	0.40
187_P	190_P	1.066	0.40
105_I	136_F	1.066	0.40
57_I	128_V	1.065	0.40
310_I	322_N	1.065	0.40
193_S	198_S	1.057	0.39
248_Y	351_I	1.052	0.39
111_L	157_A	1.049	0.39
45_Y	65_I	1.042	0.39
309_A	328_L	1.039	0.38
154_N	236_P	1.038	0.38
41_N	45_Y	1.033	0.38
186_S	193_S	1.033	0.38
323_I	328_L	1.027	0.38
145_V	356_R	1.021	0.37
305_V	330_S	1.010	0.37
111_L	146_R	1.010	0.37
46_F	107_V	1.008	0.37
35_P	42_H	0.995	0.36
201_V	358_Y	0.995	0.36
34_N	124_R	0.993	0.36
307_S	316_D	0.992	0.36
9_I	16_R	0.991	0.36
211_G	242_V	0.982	0.35
316_D	330_S	0.978	0.35
146_R	155_C	0.972	0.35
311_V	321_K	0.969	0.35
288_S	299_K	0.969	0.35
146_R	157_A	0.966	0.34
205_L	208_K	0.963	0.34
247_A	253_K	0.962	0.34
288_S	292_S	0.961	0.34
329_G	333_S	0.953	0.34
315_P	337_S	0.950	0.34
202_S	215_Y	0.949	0.34
305_V	324_G	0.944	0.33
137_G	284_T	0.940	0.33
316_D	324_G	0.939	0.33
203_G	222_D	0.935	0.33
122_V	157_A	0.934	0.33
114_D	154_N	0.933	0.33
41_N	44_R	0.931	0.33
361_G	364_G	0.931	0.33
212_L	242_V	0.931	0.33
126_E	155_C	0.928	0.32
339_K	365_S	0.928	0.32
231_K	238_V	0.928	0.32
311_V	330_S	0.927	0.32
58_F	124_R	0.921	0.32
150_I	356_R	0.918	0.32
328_L	335_S	0.915	0.32
296_S	301_K	0.912	0.32
346_G	362_Q	0.909	0.31
320_S	336_G	0.907	0.31
185_A	282_P	0.903	0.31
114_D	181_S	0.897	0.31
311_V	318_N	0.894	0.31
149_D	248_Y	0.893	0.31
27_C	64_A	0.890	0.31
289_S	299_K	0.887	0.30
168_D	172_R	0.882	0.30
311_V	329_G	0.882	0.30
187_P	193_S	0.877	0.30
144_I	167_V	0.876	0.30
109_M	160_V	0.871	0.30
64_A	276_K	0.869	0.30
316_D	321_K	0.869	0.30
108_E	147_H	0.864	0.29
311_V	324_G	0.858	0.29
254_N	268_Y	0.855	0.29
312_M	315_P	0.855	0.29
292_S	365_S	0.850	0.29
232_G	237_T	0.846	0.28
11_V	46_F	0.845	0.28
296_S	325_T	0.842	0.28
170_K	177_M	0.842	0.28
350_V	361_G	0.840	0.28
324_G	331_T	0.836	0.28
309_A	329_G	0.829	0.28
238_V	241_K	0.829	0.28
271_V	279_S	0.828	0.28
309_A	318_N	0.822	0.27
308_A	316_D	0.821	0.27
187_P	191_T	0.820	0.27
215_Y	281_A	0.819	0.27
328_L	332_I	0.815	0.27
272_T	276_K	0.814	0.27
304_G	316_D	0.813	0.27
29_L	63_E	0.811	0.27
306_S	311_V	0.805	0.26
106_G	109_M	0.802	0.26
314_K	333_S	0.800	0.26
14_Y	17_P	0.796	0.26
231_K	235_F	0.796	0.26
309_A	321_K	0.795	0.26
329_G	335_S	0.795	0.26
289_S	293_S	0.795	0.26
186_S	191_T	0.794	0.26
310_I	330_S	0.793	0.26
287_T	292_S	0.793	0.26
262_I	271_V	0.790	0.26
208_K	213_R	0.788	0.26
187_P	195_P	0.788	0.26
310_I	320_S	0.786	0.26
39_A	110_C	0.781	0.25
129_F	173_V	0.779	0.25
329_G	332_I	0.778	0.25
66_C	140_P	0.778	0.25
311_V	335_S	0.772	0.25
130_V	134_N	0.771	0.25
220_W	272_T	0.770	0.25
304_G	330_S	0.769	0.25
298_G	363_F	0.769	0.25
53_A	59_V	0.766	0.25
53_A	80_I	0.764	0.25
196_S	202_S	0.762	0.25
265_S	353_K	0.762	0.25
331_T	336_G	0.761	0.25
53_A	159_W	0.758	0.24
42_H	103_L	0.753	0.24
309_A	314_K	0.750	0.24
31_Y	146_R	0.749	0.24
103_L	211_G	0.748	0.24
201_V	206_K	0.748	0.24
305_V	311_V	0.747	0.24
321_K	336_G	0.744	0.24
64_A	118_H	0.733	0.23
312_M	316_D	0.731	0.23
66_C	78_N	0.727	0.23
311_V	320_S	0.724	0.23
202_S	233_I	0.723	0.23
31_Y	111_L	0.722	0.23
216_S	223_K	0.719	0.23
305_V	359_I	0.717	0.23
12_N	17_P	0.716	0.23
32_T	124_R	0.715	0.23
280_S	287_T	0.715	0.23
323_I	326_V	0.715	0.23
312_M	317_R	0.713	0.22
34_N	46_F	0.713	0.22
146_R	153_K	0.710	0.22
33_A	111_L	0.708	0.22
304_G	311_V	0.708	0.22
261_Y	268_Y	0.708	0.22
213_R	238_V	0.707	0.22
234_G	238_V	0.706	0.22
169_F	172_R	0.704	0.22
42_H	45_Y	0.702	0.22
113_K	154_N	0.702	0.22
40_D	134_N	0.700	0.22
184_K	358_Y	0.700	0.22
323_I	335_S	0.698	0.22
259_T	270_D	0.697	0.22
23_G	347_Y	0.696	0.22
345_N	365_S	0.695	0.22
22_Q	103_L	0.694	0.22
101_N	147_H	0.693	0.22
111_L	125_T	0.693	0.22
328_L	331_T	0.692	0.22
150_I	153_K	0.690	0.22
155_C	160_V	0.689	0.22
331_T	334_I	0.688	0.21
326_V	331_T	0.687	0.21
311_V	336_G	0.685	0.21
323_I	331_T	0.684	0.21
311_V	322_N	0.683	0.21
324_G	333_S	0.680	0.21
310_I	324_G	0.679	0.21
113_K	213_R	0.677	0.21
127_D	213_R	0.675	0.21
153_K	160_V	0.671	0.21
188_T	192_T	0.670	0.21
333_S	336_G	0.670	0.21
121_T	125_T	0.669	0.21
78_N	152_H	0.669	0.21
42_H	46_F	0.669	0.21
73_V	80_I	0.668	0.21
75_Y	80_I	0.666	0.21
111_L	153_K	0.665	0.21
56_H	65_I	0.664	0.21
307_S	311_V	0.663	0.21
25_K	171_N	0.662	0.20
305_V	309_A	0.658	0.20
55_A	74_A	0.657	0.20
118_H	146_R	0.656	0.20
322_N	328_L	0.656	0.20
320_S	333_S	0.655	0.20
303_V	307_S	0.655	0.20
52_Y	138_L	0.652	0.20
72_E	173_V	0.652	0.20
324_G	332_I	0.651	0.20
147_H	156_P	0.648	0.20
226_V	275_V	0.644	0.20
277_T	288_S	0.642	0.20
154_N	238_V	0.640	0.20
206_K	242_V	0.639	0.20
309_A	322_N	0.639	0.20
111_L	117_F	0.638	0.20
326_V	336_G	0.638	0.20
228_T	237_T	0.635	0.19
136_F	153_K	0.633	0.19
289_S	304_G	0.633	0.19
111_L	160_V	0.632	0.19
14_Y	19_L	0.627	0.19
334_I	340_G	0.627	0.19
28_V	158_P	0.627	0.19
23_G	115_G	0.626	0.19
334_I	339_K	0.624	0.19
46_F	54_S	0.623	0.19
114_D	236_P	0.619	0.19
41_N	358_Y	0.619	0.19
311_V	331_T	0.618	0.19
307_S	318_N	0.617	0.19
322_N	330_S	0.616	0.19
167_V	179_G	0.614	0.19
62_A	122_V	0.614	0.19
155_C	172_R	0.613	0.19
26_K	69_P	0.613	0.19
30_H	101_N	0.613	0.19
141_I	355_K	0.612	0.19
250_Y	338_V	0.610	0.19
75_Y	108_E	0.608	0.18
153_K	172_R	0.607	0.18
314_K	324_G	0.607	0.18
202_S	205_L	0.606	0.18
8_Y	19_L	0.605	0.18
287_T	293_S	0.605	0.18
307_S	320_S	0.604	0.18
259_T	266_D	0.601	0.18
167_V	177_M	0.600	0.18
111_L	122_V	0.600	0.18
217_K	256_K	0.600	0.18
271_V	274_S	0.597	0.18
133_C	143_D	0.597	0.18
189_K	197_S	0.595	0.18
321_K	331_T	0.595	0.18
304_G	307_S	0.593	0.18
27_C	129_F	0.593	0.18
57_I	68_I	0.592	0.18
109_M	169_F	0.592	0.18
55_A	170_K	0.591	0.18
42_H	138_L	0.590	0.18
114_D	208_K	0.590	0.18
335_S	341_K	0.589	0.18
179_G	184_K	0.588	0.18
304_G	335_S	0.588	0.18
24_V	70_L	0.587	0.18
316_D	322_N	0.586	0.18
56_H	69_P	0.586	0.18
229_V	239_V	0.585	0.18
320_S	328_L	0.583	0.18
289_S	292_S	0.581	0.18
309_A	317_R	0.581	0.18
53_A	123_E	0.580	0.18
106_G	132_L	0.579	0.17
322_N	335_S	0.579	0.17
260_Y	264_A	0.577	0.17
231_K	240_E	0.577	0.17
31_Y	122_V	0.576	0.17
31_Y	155_C	0.575	0.17
321_K	326_V	0.574	0.17
304_G	324_G	0.574	0.17
283_K	351_I	0.574	0.17
32_T	42_H	0.570	0.17
31_Y	153_K	0.568	0.17
107_V	128_V	0.568	0.17
8_Y	14_Y	0.568	0.17
187_P	204_S	0.567	0.17
253_K	260_Y	0.566	0.17
212_L	215_Y	0.566	0.17
146_R	160_V	0.566	0.17
45_Y	120_D	0.565	0.17
57_I	111_L	0.562	0.17
70_L	131_E	0.560	0.17
127_D	145_V	0.559	0.17
108_E	155_C	0.558	0.17
336_G	339_K	0.558	0.17
242_V	245_G	0.558	0.17
10_P	16_R	0.557	0.17
30_H	156_P	0.557	0.17
294_I	365_S	0.556	0.17
64_A	284_T	0.554	0.17
324_G	335_S	0.553	0.17
226_V	240_E	0.552	0.17
296_S	313_D	0.551	0.17
326_V	329_G	0.549	0.16
31_Y	157_A	0.549	0.16
215_Y	218_P	0.549	0.16
287_T	301_K	0.548	0.16
288_S	300_I	0.548	0.16
32_T	172_R	0.547	0.16
314_K	321_K	0.547	0.16
312_M	320_S	0.546	0.16
175_A	179_G	0.544	0.16
132_L	140_P	0.543	0.16
286_S	344_S	0.543	0.16
215_Y	224_D	0.542	0.16
215_Y	219_S	0.542	0.16
297_V	308_A	0.537	0.16
304_G	329_G	0.537	0.16
306_S	326_V	0.537	0.16
211_G	238_V	0.536	0.16
300_I	329_G	0.535	0.16
217_K	231_K	0.535	0.16
232_G	239_V	0.535	0.16
326_V	333_S	0.535	0.16
311_V	323_I	0.530	0.16
315_P	318_N	0.530	0.16
259_T	264_A	0.530	0.16
284_T	287_T	0.530	0.16
328_L	333_S	0.530	0.16
138_L	143_D	0.528	0.16
15_T	40_D	0.527	0.16
76_H	104_S	0.527	0.16
10_P	14_Y	0.525	0.16
128_V	143_D	0.525	0.16
46_F	51_V	0.523	0.16
55_A	146_R	0.522	0.16
61_K	117_F	0.522	0.16
314_K	331_T	0.520	0.16
357_G	365_S	0.519	0.16
116_S	160_V	0.518	0.16
217_K	230_N	0.516	0.15
58_F	65_I	0.515	0.15
55_A	59_V	0.513	0.15
301_K	306_S	0.511	0.15
179_G	182_V	0.511	0.15
183_S	194_S	0.510	0.15
235_F	241_K	0.509	0.15
325_T	330_S	0.508	0.15
111_L	141_I	0.507	0.15
246_S	254_N	0.507	0.15
15_T	73_V	0.507	0.15
186_S	198_S	0.507	0.15
232_G	235_F	0.502	0.15
339_K	358_Y	0.502	0.15
204_S	209_V	0.502	0.15
117_F	160_V	0.502	0.15
126_E	143_D	0.501	0.15
125_T	162_N	0.501	0.15
229_V	237_T	0.501	0.15
106_G	146_R	0.501	0.15
215_Y	251_K	0.501	0.15
55_A	68_I	0.500	0.15
330_S	334_I	0.500	0.15

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4knkA	1	0.4632	100	0.581	Contact Map
4ivvA	1	0.4169	100	0.597	Contact Map
3rdrA	4	0.4114	100	0.633	Contact Map
1yb0A	3	0.4278	100	0.645	Contact Map
4olsA	2	0.4305	100	0.646	Contact Map
4x36A	2	0.7793	100	0.656	Contact Map
1j3gA	1	0.4469	100	0.677	Contact Map
4bxjA	4	0.624	100	0.697	Contact Map
3d2yA	3	0.624	100	0.699	Contact Map
4bolA	2	0.5967	100	0.704	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0101 seconds.