GREMLIN Database
YOMD - SPBc2 prophage-derived uncharacterized protein YomD
UniProt: O31981 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 274 (217)
Sequences: 145 (142)
Seq/√Len: 9.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
53_W117_W4.2770.99
168_P171_C3.5400.97
167_L170_L3.5170.97
194_C201_L3.4670.96
60_F65_R3.4410.96
47_C111_C3.3090.95
141_V148_F3.2990.95
195_R202_F3.2160.94
178_G181_Y3.1720.94
202_F205_E2.8700.90
168_P172_K2.8210.89
182_A186_N2.8210.89
45_V109_A2.6720.86
180_Q216_S2.6190.85
24_L32_I2.6130.85
124_F129_E2.5920.85
96_I99_T2.5400.83
165_E168_P2.3330.78
216_S219_K2.2160.74
93_G111_C2.1970.73
102_N105_S2.1790.72
60_F124_F2.0290.67
140_T179_V1.9190.62
167_L171_C1.9130.62
102_N114_G1.8990.61
66_C69_C1.8670.60
38_N41_T1.8520.59
123_N128_E1.8480.59
206_N216_S1.7680.56
205_E212_G1.7540.55
216_S221_L1.7400.54
165_E170_L1.7390.54
136_A140_T1.7230.54
161_H168_P1.7140.53
198_Y201_L1.6890.52
166_N185_H1.6840.52
169_F184_L1.6760.51
197_C201_L1.6660.51
130_C133_C1.6430.50
20_F57_Y1.6310.49
195_R201_L1.6280.49
167_L172_K1.6250.49
167_L176_D1.6200.49
180_Q206_N1.6040.48
45_V53_W1.5930.48
205_E209_R1.5670.47
38_N186_N1.5340.45
148_F169_F1.5230.45
26_Q29_Y1.5200.44
181_Y184_L1.4910.43
44_K52_T1.4170.40
209_R214_I1.4090.40
169_F177_L1.3810.38
103_C186_N1.3690.38
145_Q155_P1.3570.37
69_C133_C1.3540.37
69_C130_C1.3540.37
192_A196_K1.3460.37
51_H115_H1.3440.37
142_E145_Q1.3300.36
167_L209_R1.3220.36
66_C133_C1.3180.36
66_C130_C1.3180.36
208_S212_G1.2960.35
65_R129_E1.2860.34
32_I96_I1.2720.34
183_P190_G1.2700.34
171_C175_I1.2580.33
177_L181_Y1.2560.33
123_N154_I1.2480.33
190_G198_Y1.2470.33
147_A225_V1.2240.32
55_V132_Q1.2200.32
184_L205_E1.2180.32
204_G212_G1.2070.31
56_N63_G1.2020.31
94_Y111_C1.1940.31
93_G108_K1.1730.30
109_A117_W1.1650.30
169_F185_H1.1560.29
141_V178_G1.1540.29
191_L194_C1.1520.29
88_R111_C1.1300.28
168_P173_E1.1120.28
191_L195_R1.1110.28
218_N221_L1.0980.27
50_N114_G1.0970.27
191_L202_F1.0920.27
26_Q58_E1.0910.27
47_C69_C1.0910.27
105_S196_K1.0780.27
57_Y121_P1.0710.26
46_R52_T1.0620.26
177_L180_Q1.0610.26
171_C174_H1.0460.25
180_Q185_H1.0390.25
56_N59_H1.0370.25
34_G47_C1.0340.25
141_V181_Y1.0200.25
129_E171_C1.0200.25
92_K108_K1.0160.24
188_V213_G1.0050.24
145_Q149_S0.9910.24
132_Q149_S0.9840.23
111_C129_E0.9760.23
166_N184_L0.9750.23
111_C133_C0.9740.23
111_C130_C0.9740.23
22_D165_E0.9660.23
80_L84_T0.9590.23
141_V144_A0.9560.22
17_Q21_I0.9410.22
126_K150_D0.9380.22
170_L173_E0.9280.22
184_L201_L0.9220.21
144_A179_V0.9200.21
72_I200_L0.9160.21
190_G194_C0.9110.21
30_I60_F0.9040.21
208_S215_S0.8980.21
169_F176_D0.8980.21
154_I159_T0.8970.21
191_L201_L0.8960.21
148_F181_Y0.8960.21
67_P93_G0.8880.20
205_E217_L0.8800.20
59_H101_K0.8750.20
126_K189_R0.8750.20
91_L121_P0.8740.20
16_T19_K0.8680.20
20_F121_P0.8630.20
54_Q64_T0.8630.20
47_C130_C0.8630.20
47_C133_C0.8630.20
166_N176_D0.8570.20
186_N189_R0.8550.19
24_L28_N0.8530.19
169_F183_P0.8520.19
194_C202_F0.8480.19
43_V143_C0.8430.19
43_V52_T0.8380.19
102_N189_R0.8380.19
140_T147_A0.8320.19
87_S110_K0.8300.19
56_N83_S0.8290.19
88_R129_E0.8280.19
203_T207_S0.8260.19
210_W233_S0.8260.19
142_E173_E0.8250.19
53_W109_A0.8220.19
219_K225_V0.8180.18
185_H218_N0.8160.18
148_F178_G0.8090.18
185_H216_S0.8040.18
190_G201_L0.8030.18
160_Y168_P0.8020.18
24_L96_I0.7960.18
45_V144_A0.7960.18
28_N47_C0.7900.18
59_H62_K0.7870.18
36_M61_K0.7820.18
143_C148_F0.7810.17
178_G184_L0.7770.17
121_P125_F0.7760.17
176_D201_L0.7730.17
50_N209_R0.7660.17
34_G40_K0.7640.17
55_V60_F0.7570.17
38_N59_H0.7560.17
187_M190_G0.7510.17
45_V124_F0.7480.17
55_V110_K0.7450.17
52_T73_E0.7440.17
63_G196_K0.7430.17
114_G200_L0.7430.17
72_I77_K0.7380.16
23_L121_P0.7300.16
90_A93_G0.7260.16
64_T164_K0.7240.16
42_K123_N0.7210.16
62_K126_K0.7200.16
153_F215_S0.7170.16
32_I45_V0.7140.16
90_A124_F0.7100.16
32_I93_G0.7080.16
170_L180_Q0.7070.16
166_N169_F0.7040.16
227_E233_S0.7010.15
45_V115_H0.7000.15
191_L200_L0.6960.15
205_E208_S0.6950.15
70_R121_P0.6940.15
26_Q47_C0.6920.15
41_T105_S0.6900.15
118_E200_L0.6880.15
41_T96_I0.6870.15
130_C178_G0.6860.15
133_C178_G0.6860.15
96_I114_G0.6820.15
65_R119_H0.6810.15
158_D198_Y0.6770.15
55_V64_T0.6770.15
115_H149_S0.6760.15
18_K88_R0.6730.15
141_V145_Q0.6720.15
88_R108_K0.6700.15
141_V179_V0.6690.15
40_K54_Q0.6670.15
59_H78_K0.6670.15
45_V51_H0.6670.15
36_M100_Y0.6620.15
60_F149_S0.6620.15
141_V158_D0.6620.15
184_L202_F0.6610.15
45_V88_R0.6570.14
24_L45_V0.6570.14
117_W129_E0.6510.14
34_G114_G0.6420.14
27_N107_L0.6340.14
25_A101_K0.6320.14
99_T102_N0.6310.14
160_Y167_L0.6290.14
159_T198_Y0.6270.14
84_T102_N0.6240.14
49_H191_L0.6230.14
69_C111_C0.6230.14
24_L34_G0.6230.14
39_S119_H0.6220.14
59_H73_E0.6220.14
47_C93_G0.6160.14
177_L212_G0.6160.14
93_G97_L0.6150.14
39_S105_S0.6150.14
47_C66_C0.6140.14
42_K54_Q0.6120.14
71_I74_G0.6120.14
54_Q193_N0.6080.13
45_V49_H0.6080.13
15_E32_I0.6070.13
185_H201_L0.6040.13
179_V222_R0.6040.13
49_H173_E0.6040.13
109_A124_F0.6030.13
25_A46_R0.6010.13
222_R229_W0.6010.13
53_W211_K0.6010.13
59_H223_E0.5990.13
45_V55_V0.5970.13
111_C119_H0.5940.13
68_E119_H0.5930.13
156_L159_T0.5920.13
172_K194_C0.5910.13
55_V119_H0.5900.13
38_N56_N0.5900.13
118_E211_K0.5890.13
125_F134_K0.5870.13
117_W170_L0.5860.13
152_G196_K0.5830.13
144_A204_G0.5810.13
36_M88_R0.5790.13
44_K88_R0.5790.13
59_H196_K0.5780.13
205_E213_G0.5770.13
230_T234_L0.5740.13
141_V207_S0.5720.13
71_I128_E0.5700.13
226_Y234_L0.5700.13
56_N122_S0.5700.13
120_L123_N0.5700.13
90_A117_W0.5660.13
161_H170_L0.5660.13
220_T229_W0.5630.13
105_S118_E0.5620.12
104_H123_N0.5600.12
204_G211_K0.5590.12
60_F185_H0.5590.12
156_L199_L0.5580.12
176_D185_H0.5570.12
45_V60_F0.5560.12
154_I233_S0.5520.12
44_K108_K0.5520.12
92_K111_C0.5510.12
82_I93_G0.5500.12
27_N30_I0.5480.12
31_H94_Y0.5480.12
32_I114_G0.5480.12
147_A231_K0.5480.12
137_K208_S0.5440.12
193_N213_G0.5430.12
121_P202_F0.5430.12
53_W65_R0.5410.12
86_K164_K0.5400.12
22_D74_G0.5400.12
21_I61_K0.5400.12
19_K22_D0.5390.12
171_C190_G0.5370.12
117_W122_S0.5370.12
129_E144_A0.5350.12
143_C147_A0.5320.12
21_I46_R0.5310.12
68_E88_R0.5290.12
41_T57_Y0.5280.12
148_F184_L0.5270.12
91_L199_L0.5250.12
182_A189_R0.5240.12
187_M207_S0.5240.12
52_T74_G0.5240.12
38_N118_E0.5210.12
51_H77_K0.5170.12
205_E214_I0.5170.12
175_I188_V0.5170.12
195_R214_I0.5160.12
137_K157_F0.5120.12
20_F47_C0.5100.12
41_T106_K0.5080.11
85_V224_A0.5080.11
32_I121_P0.5070.11
84_T93_G0.5040.11
148_F158_D0.5030.11
121_P212_G0.5030.11
151_R176_D0.5030.11
41_T143_C0.5020.11
53_W125_F0.5010.11
20_F25_A0.5010.11
137_K144_A0.5010.11
56_N73_E0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oq2A 1 0.5438 97.6 0.899 Contact Map
3hrlA 1 0.3212 96.9 0.91 Contact Map
1vsrA 1 0.4234 96.7 0.912 Contact Map
3r3pA 3 0.3467 96.5 0.914 Contact Map
4parB 3 0.5657 96.4 0.915 Contact Map
1cw0A 1 0.4964 96.1 0.918 Contact Map
2k2dA 1 0.1679 87.5 0.938 Contact Map
1yuzA 2 0.2701 65 0.95 Contact Map
1lkoA 3 0.281 59.3 0.952 Contact Map
4aybP 1 0.1569 59.2 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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