GREMLIN Database
YONS - SPBc2 prophage-derived uncharacterized lipoprotein YonS
UniProt: O31942 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 203 (192)
Sequences: 177 (159)
Seq/√Len: 11.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
148_D158_G3.7590.99
19_L22_C3.6110.98
84_P113_T3.3800.98
31_S164_F3.2400.97
177_R196_D3.0240.95
128_A134_Q2.8730.94
123_S147_L2.7780.93
86_Q111_E2.6620.91
74_S77_E2.3240.84
4_F21_A2.3210.83
134_Q154_V2.3010.83
12_L56_K2.2080.80
70_V93_I2.2060.80
186_E191_L2.1610.79
150_Y156_D2.0850.76
124_L148_D2.0470.75
94_A164_F2.0310.74
111_E155_N2.0190.74
54_P58_G2.0040.73
109_E149_E1.9950.73
140_L143_S1.9290.70
54_P93_I1.9030.69
21_A87_F1.8970.69
180_I183_P1.8940.69
21_A104_I1.8240.65
122_P158_G1.8180.65
129_T173_L1.8060.65
96_V102_P1.8020.65
149_E176_I1.7950.64
84_P115_D1.7430.62
30_S34_D1.7310.61
37_N75_N1.7110.60
48_D164_F1.7060.60
58_G70_V1.6670.58
190_N193_D1.6220.56
57_V89_V1.6090.55
123_S130_S1.5910.55
27_E104_I1.5480.52
184_F190_N1.5260.51
93_I183_P1.5240.51
121_R134_Q1.5180.51
7_L16_L1.5110.51
122_P156_D1.4980.50
54_P70_V1.4540.48
138_P162_Y1.4040.45
21_A97_A1.4000.45
57_V95_A1.3930.45
35_T42_N1.3920.45
106_V110_S1.3830.44
58_G93_I1.3750.44
89_V145_R1.3640.43
29_S48_D1.3590.43
68_A95_A1.3550.43
10_L41_T1.3350.42
113_T155_N1.3340.42
6_K12_L1.3160.41
121_R124_L1.3030.41
147_L156_D1.3010.40
5_K106_V1.2960.40
87_F180_I1.2820.40
127_L164_F1.2730.39
155_N175_S1.2680.39
82_T192_G1.2680.39
104_I176_I1.2650.39
128_A154_V1.2620.39
135_I139_S1.2350.37
8_G21_A1.2350.37
17_I28_S1.2200.37
124_L158_G1.1830.35
125_A158_G1.1800.35
58_G104_I1.1740.35
14_T164_F1.1710.34
150_Y154_V1.1680.34
42_N45_E1.1610.34
129_T133_V1.1550.34
12_L32_S1.1440.33
80_V87_F1.1430.33
38_A44_S1.1130.32
15_S172_D1.1130.32
114_S152_G1.1000.31
114_S174_E1.0980.31
7_L15_S1.0940.31
127_L150_Y1.0920.31
117_V177_R1.0890.31
117_V151_V1.0800.31
148_D156_D1.0780.30
6_K13_I1.0760.30
193_D198_K1.0650.30
84_P118_V1.0640.30
15_S20_A1.0600.30
81_K88_T1.0580.30
152_G185_N1.0490.29
182_S190_N1.0480.29
41_T46_S1.0450.29
190_N198_K1.0320.29
14_T39_T1.0310.29
21_A24_N1.0250.28
25_S176_I1.0240.28
105_D122_P1.0210.28
109_E157_S1.0210.28
32_S42_N1.0210.28
34_D178_L1.0050.28
104_I159_S0.9960.27
42_N48_D0.9930.27
12_L15_S0.9780.26
126_Q156_D0.9760.26
56_K166_N0.9690.26
131_T180_I0.9580.26
23_K121_R0.9460.25
13_I34_D0.9450.25
87_F106_V0.9440.25
30_S178_L0.9260.25
152_G179_R0.9250.24
78_T130_S0.9210.24
122_P162_Y0.9180.24
68_A136_D0.9150.24
158_G174_E0.9140.24
104_I110_S0.9070.24
70_V73_I0.9050.24
58_G66_G0.9010.24
127_L135_I0.9000.24
24_N171_K0.9000.24
94_A168_E0.8920.23
74_S111_E0.8850.23
128_A189_K0.8770.23
171_K187_D0.8770.23
4_F7_L0.8740.23
39_T44_S0.8640.22
92_V190_N0.8630.22
74_S92_V0.8580.22
119_R149_E0.8520.22
87_F118_V0.8510.22
186_E189_K0.8490.22
71_M78_T0.8480.22
101_L183_P0.8470.22
52_N68_A0.8470.22
122_P148_D0.8290.21
53_G127_L0.8290.21
11_L82_T0.8250.21
124_L147_L0.8180.21
143_S180_I0.8140.21
86_Q127_L0.8110.21
26_E79_T0.8070.20
52_N109_E0.8040.20
13_I130_S0.8030.20
91_K124_L0.8010.20
120_F180_I0.8000.20
63_I164_F0.7960.20
39_T64_D0.7960.20
16_L33_E0.7910.20
57_V182_S0.7890.20
54_P183_P0.7850.20
126_Q134_Q0.7840.20
96_V149_E0.7840.20
27_E33_E0.7810.20
17_I30_S0.7770.20
85_I191_L0.7690.19
117_V175_S0.7670.19
102_P133_V0.7650.19
23_K95_A0.7630.19
85_I120_F0.7620.19
61_Y103_F0.7570.19
38_A42_N0.7550.19
16_L21_A0.7520.19
4_F16_L0.7520.19
22_C120_F0.7490.19
17_I85_I0.7470.19
40_D46_S0.7470.19
13_I16_L0.7450.19
149_E189_K0.7420.18
12_L33_E0.7420.18
105_D163_V0.7280.18
127_L152_G0.7260.18
109_E168_E0.7230.18
65_G125_A0.7220.18
146_L182_S0.7170.18
54_P59_D0.7140.18
66_G165_D0.7050.17
167_E176_I0.7000.17
101_L159_S0.6950.17
110_S146_L0.6910.17
58_G84_P0.6860.17
58_G105_D0.6810.17
19_L114_S0.6800.17
90_K109_E0.6780.17
176_I190_N0.6750.17
20_A34_D0.6720.16
14_T17_I0.6700.16
85_I150_Y0.6680.16
70_V161_I0.6660.16
117_V186_E0.6650.16
15_S31_S0.6600.16
54_P161_I0.6590.16
33_E51_V0.6570.16
93_I180_I0.6540.16
37_N139_S0.6540.16
83_G146_L0.6500.16
139_S163_V0.6460.16
8_G51_V0.6400.16
120_F152_G0.6390.16
94_A177_R0.6360.16
150_Y153_K0.6340.15
18_L61_Y0.6330.15
70_V76_K0.6320.15
132_G187_D0.6290.15
59_D86_Q0.6250.15
45_E92_V0.6240.15
132_G186_E0.6200.15
13_I19_L0.6200.15
188_L192_G0.6200.15
183_P191_L0.6160.15
114_S157_S0.6130.15
108_I146_L0.6110.15
92_V140_L0.6110.15
87_F120_F0.6060.15
117_V121_R0.6060.15
79_T152_G0.6040.15
29_S46_S0.6040.15
12_L153_K0.6020.15
90_K163_V0.6020.15
83_G184_F0.6010.15
13_I64_D0.6000.15
128_A188_L0.5990.15
93_I124_L0.5970.15
92_V198_K0.5960.15
106_V165_D0.5960.15
184_F188_L0.5950.15
25_S31_S0.5950.15
117_V184_F0.5950.15
4_F8_G0.5930.14
153_K177_R0.5920.14
129_T148_D0.5920.14
52_N63_I0.5900.14
59_D92_V0.5880.14
95_A161_I0.5840.14
81_K189_K0.5830.14
24_N185_N0.5820.14
133_V159_S0.5820.14
22_C66_G0.5810.14
130_S150_Y0.5740.14
141_L191_L0.5730.14
113_T175_S0.5730.14
105_D123_S0.5730.14
7_L11_L0.5720.14
124_L134_Q0.5710.14
121_R148_D0.5670.14
105_D142_E0.5660.14
11_L177_R0.5650.14
23_K59_D0.5650.14
175_S200_N0.5610.14
5_K19_L0.5580.14
194_K199_I0.5540.14
56_K87_F0.5510.13
101_L151_V0.5510.13
146_L156_D0.5470.13
62_E67_T0.5470.13
94_A160_I0.5460.13
155_N165_D0.5430.13
32_S49_I0.5420.13
38_A41_T0.5410.13
143_S146_L0.5390.13
166_N179_R0.5360.13
53_G104_I0.5360.13
103_F160_I0.5360.13
105_D173_L0.5340.13
59_D155_N0.5330.13
92_V186_E0.5330.13
83_G197_L0.5280.13
147_L188_L0.5280.13
133_V165_D0.5280.13
87_F135_I0.5250.13
132_G135_I0.5220.13
42_N116_E0.5220.13
110_S153_K0.5190.13
121_R147_L0.5180.13
20_A26_E0.5170.13
15_S130_S0.5140.13
121_R180_I0.5130.13
51_V91_K0.5110.13
69_K115_D0.5090.13
111_E132_G0.5090.13
103_F176_I0.5080.13
83_G183_P0.5070.12
94_A178_L0.5040.12
120_F183_P0.5040.12
120_F158_G0.5020.12
113_T133_V0.5000.12
26_E40_D0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cfuA 1 0.6059 98.7 0.809 Contact Map
4lesA 1 0.5911 98.3 0.83 Contact Map
4r4gA 1 0.5764 98.2 0.833 Contact Map
4eaeA 2 0.7635 97.1 0.868 Contact Map
3ucpA 1 0.5813 95.7 0.886 Contact Map
3pmqA 1 0.5419 95.2 0.89 Contact Map
2llgA 1 0.6404 94.6 0.894 Contact Map
5bxgA 1 0.6946 92.9 0.901 Contact Map
3qfgA 2 0.6059 92.3 0.903 Contact Map
4peuA 1 0.4631 92.3 0.903 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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