GREMLIN Database
YOQW - Putative SOS response-associated peptidase YoqW
UniProt: O31916 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 224 (203)
Sequences: 3426 (2490)
Seq/√Len: 174.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
101_A130_F4.3231.00
41_I148_C4.2721.00
82_L151_I4.1771.00
43_T56_L4.0661.00
133_L149_T3.8701.00
98_I175_E3.4261.00
18_F129_A3.3761.00
103_S119_R2.8031.00
116_I205_Q2.7131.00
171_T174_N2.6461.00
97_C132_G2.4791.00
79_A151_I2.4521.00
91_P135_E2.4111.00
130_F150_I2.3691.00
45_I54_G2.3321.00
121_K202_E2.2871.00
121_K204_Y2.1261.00
86_P89_R2.0391.00
136_K146_Y1.9911.00
98_I129_A1.9111.00
76_N163_H1.9031.00
120_I162_I1.8741.00
106_E163_H1.8601.00
83_S92_L1.8471.00
51_N176_K1.8081.00
74_M87_S1.7211.00
5_F41_I1.6971.00
95_K135_E1.6961.00
77_A149_T1.6921.00
10_E13_D1.6741.00
17_Q175_E1.6581.00
129_A175_E1.6461.00
110_L114_T1.6451.00
104_F159_M1.6411.00
174_N177_E1.6121.00
156_N166_M1.6091.00
9_S102_D1.5911.00
99_I148_C1.5831.00
157_E160_E1.5541.00
120_I159_M1.5471.00
61_I145_L1.5321.00
6_T119_R1.5101.00
99_I150_I1.5091.00
35_V41_I1.4851.00
43_T148_C1.4811.00
32_S39_Q1.4761.00
7_L35_V1.4721.00
196_Y201_M1.4521.00
82_L92_L1.4511.00
79_A193_L1.4191.00
12_D16_E1.4191.00
122_L126_N1.3961.00
136_K144_P1.3661.00
83_S190_Q1.3631.00
34_N117_P1.3511.00
138_N144_P1.3211.00
128_F201_M1.3211.00
107_W115_K1.2791.00
45_I52_R1.2781.00
169_I201_M1.2441.00
153_T195_P1.2431.00
158_L199_D1.2421.00
108_K118_M1.2341.00
5_F101_A1.2331.00
122_L128_F1.2241.00
114_T208_S1.2101.00
43_T97_C1.1931.00
81_T85_K1.1911.00
20_I53_L1.1901.00
90_K93_V1.1761.00
47_D50_N1.1631.00
45_I134_Y1.1581.00
119_R204_Y1.1511.00
91_P95_K1.1491.00
170_L174_N1.1461.00
32_S35_V1.1441.00
123_K202_E1.1421.00
118_M205_Q1.1391.00
98_I170_L1.1241.00
158_L201_M1.1201.00
11_F15_I1.1151.00
99_I132_G1.1111.00
153_T168_V1.1091.00
131_A168_V1.1061.00
81_T88_F1.1041.00
120_I203_A1.0991.00
172_D175_E1.0761.00
21_D50_N1.0721.00
80_E165_R1.0531.00
95_K134_Y1.0481.00
76_N106_E1.0320.99
9_S127_L1.0250.99
137_W140_P1.0200.99
42_L53_L1.0190.99
65_A70_I1.0180.99
198_A201_M1.0160.99
43_T99_I1.0140.99
56_L146_Y1.0090.99
192_L195_P1.0050.99
128_F175_E1.0000.99
139_T143_N0.9950.99
3_G75_I0.9920.99
70_I73_K0.9880.99
158_L203_A0.9880.99
4_R34_N0.9870.99
109_R115_K0.9820.99
154_K164_D0.9810.99
41_I99_I0.9740.99
44_I51_N0.9640.99
97_C134_Y0.9530.99
153_T156_N0.9490.99
153_T166_M0.9480.99
180_N183_N0.9460.99
157_E161_D0.9390.99
122_L171_T0.9320.99
60_L147_T0.9310.99
61_I74_M0.9220.99
38_S72_Y0.9120.99
61_I147_T0.9100.99
5_F42_L0.9080.99
132_G149_T0.9040.99
36_A39_Q0.9040.99
177_E191_S0.9040.99
111_D114_T0.9040.99
4_R107_W0.8920.98
54_G146_Y0.8820.98
34_N107_W0.8800.98
74_M88_F0.8800.98
8_F102_D0.8790.98
158_L161_D0.8660.98
59_G75_I0.8660.98
38_S57_R0.8650.98
138_N143_N0.8630.98
107_W117_P0.8610.98
121_K125_S0.8570.98
104_F156_N0.8510.98
110_L113_K0.8450.98
177_E188_Y0.8360.98
60_L135_E0.8260.97
150_I167_P0.8260.97
110_L116_I0.8240.97
2_C76_N0.8240.97
122_L201_M0.8230.97
188_Y191_S0.8200.97
85_K88_F0.8150.97
177_E180_N0.8150.97
67_D71_G0.7910.97
82_L133_L0.7780.96
89_R93_V0.7750.96
67_D73_K0.7720.96
171_T200_D0.7690.96
15_I22_Q0.7680.96
187_D191_S0.7630.96
17_Q126_N0.7630.96
90_K135_E0.7570.96
36_A107_W0.7520.95
77_A88_F0.7460.95
104_F161_D0.7400.95
155_P164_D0.7390.95
58_W96_R0.7370.95
18_F175_E0.7360.95
33_Y117_P0.7350.95
46_N51_N0.7330.95
90_K94_S0.7330.95
40_N55_K0.7320.95
122_L200_D0.7310.95
79_A153_T0.7250.95
5_F35_V0.7250.95
174_N194_Q0.7250.95
168_V195_P0.7250.95
109_R114_T0.7230.94
42_L55_K0.7200.94
154_K157_E0.7160.94
151_I168_V0.7160.94
58_W167_P0.7140.94
155_P160_E0.7090.94
108_K115_K0.7070.94
156_N161_D0.7060.94
174_N192_L0.7030.94
7_L42_L0.7020.94
3_G37_P0.7010.93
6_T103_S0.6970.93
189_L192_L0.6960.93
104_F169_I0.6950.93
139_T144_P0.6950.93
63_P90_K0.6900.93
9_S13_D0.6860.93
176_K180_N0.6860.93
63_P135_E0.6830.93
2_C163_H0.6760.92
138_N142_G0.6730.92
197_D200_D0.6680.92
5_F148_C0.6670.92
45_I146_Y0.6650.92
128_F169_I0.6630.91
196_Y200_D0.6630.91
61_I67_D0.6620.91
103_S121_K0.6610.91
189_L193_L0.6600.91
15_I20_I0.6550.91
122_L127_L0.6530.91
181_P189_L0.6480.91
183_N188_Y0.6470.90
78_R106_E0.6470.90
106_E165_R0.6440.90
137_W145_L0.6440.90
71_G74_M0.6410.90
70_I74_M0.6370.90
5_F100_P0.6350.90
41_I58_W0.6340.90
13_D16_E0.6320.89
44_I100_P0.6320.89
60_L74_M0.6300.89
9_S14_I0.6270.89
84_E141_E0.6240.89
81_T84_E0.6220.89
104_F158_L0.6210.89
5_F36_A0.6200.89
101_A150_I0.6200.89
5_F99_I0.6200.89
108_K116_I0.6170.88
155_P158_L0.6160.88
118_M162_I0.6160.88
67_D70_I0.6150.88
36_A117_P0.6140.88
132_G150_I0.6130.88
12_D21_D0.6120.88
57_R145_L0.6090.88
130_F167_P0.6090.88
37_P75_I0.6090.88
3_G107_W0.6060.87
34_N103_S0.6030.87
14_I22_Q0.6010.87
126_N172_D0.5990.87
75_I149_T0.5960.87
60_L72_Y0.5950.86
110_L118_M0.5930.86
92_L189_L0.5910.86
94_S135_E0.5890.86
57_R68_E0.5850.85
114_T199_D0.5830.85
108_K111_D0.5820.85
2_C106_E0.5810.85
158_L200_D0.5790.85
60_L87_S0.5770.85
74_M149_T0.5760.85
25_P28_E0.5740.84
9_S12_D0.5730.84
122_L125_S0.5720.84
130_F169_I0.5670.84
169_I195_P0.5670.84
156_N195_P0.5670.84
56_L148_C0.5660.84
19_N176_K0.5660.84
151_I193_L0.5620.83
78_R163_H0.5600.83
18_F44_I0.5600.83
196_Y199_D0.5600.83
65_A71_G0.5590.83
109_R164_D0.5580.83
162_I203_A0.5580.83
68_E145_L0.5580.83
33_Y36_A0.5570.83
72_Y87_S0.5550.82
205_Q208_S0.5550.82
80_E154_K0.5530.82
108_K161_D0.5520.82
49_S98_I0.5490.82
69_K72_Y0.5490.82
77_A82_L0.5470.81
17_Q172_D0.5470.81
191_S194_Q0.5410.81
29_Y42_L0.5390.81
159_M162_I0.5370.80
61_I68_E0.5370.80
80_E151_I0.5370.80
105_Y206_V0.5320.80
156_N198_A0.5290.79
38_S75_I0.5270.79
120_I164_D0.5270.79
4_R37_P0.5260.79
46_N49_S0.5230.79
105_Y117_P0.5220.78
105_Y165_R0.5220.78
51_N179_L0.5210.78
158_L169_I0.5190.78
64_W67_D0.5140.77
5_F132_G0.5130.77
14_I18_F0.5120.77
83_S93_V0.5110.77
16_E22_Q0.5110.77
137_W147_T0.5100.77
109_R113_K0.5090.77
7_L14_I0.5080.77
79_A85_K0.5080.77
64_W85_K0.5070.76
6_T102_D0.5070.76
40_N57_R0.5060.76
18_F21_D0.5030.76
79_A168_V0.5030.76
22_Q25_P0.5030.76
42_L148_C0.5010.76
43_T132_G0.5000.75
50_N144_P0.5000.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2icuA 1 0.9241 100 0.09 Contact Map
2bdvA 1 0.9241 100 0.093 Contact Map
2f20A 1 0.9732 100 0.101 Contact Map
2aegA 1 0.9062 100 0.135 Contact Map
1zn6A 1 0.8839 100 0.146 Contact Map
2jd3A 2 0.3839 17.4 0.955 Contact Map
2gs0B 1 0.0625 16.7 0.955 Contact Map
3bsuA 1 0.2188 9.6 0.96 Contact Map
2b3gB 2 0.1071 6.6 0.963 Contact Map
2iiiA 2 0.1741 5.9 0.963 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.