GREMLIN Database
YORG - SPBc2 prophage-derived uncharacterized protein YorG
UniProt: O31907 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 323 (286)
Sequences: 206 (181)
Seq/√Len: 10.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_K87_Q5.2961.00
29_N208_R5.0311.00
45_L89_I4.2420.99
20_K53_A3.9900.99
101_A131_V3.9460.99
94_V166_R3.5750.98
94_V171_V3.1190.95
113_R126_E3.0150.94
53_A211_F2.9350.93
35_Q181_L2.8080.92
111_V117_G2.7560.91
13_V57_V2.6450.89
149_A214_I2.5780.87
58_Q86_Y2.3870.83
33_T54_I2.2690.79
42_P88_T2.2620.79
65_W101_A2.1800.77
147_F171_V2.1740.76
162_K173_D2.1530.76
73_K137_K2.1170.74
47_F50_G2.1050.74
298_K301_E2.0310.71
115_K124_W1.9610.68
24_I35_Q1.9230.67
18_E52_N1.9160.66
134_E164_D1.9090.66
134_E187_D1.9040.66
121_F134_E1.8650.64
235_E250_E1.8410.63
35_Q221_F1.8310.63
42_P90_I1.8180.62
34_K221_F1.7990.61
22_I147_F1.7570.59
243_I250_E1.7150.58
17_L53_A1.7140.57
101_A154_D1.6920.56
32_K92_D1.6890.56
29_N46_P1.6240.53
102_T127_Y1.6240.53
78_N84_E1.6110.53
24_I194_K1.6050.52
118_N160_Y1.5740.51
101_A204_E1.5660.51
290_E295_K1.5380.49
173_D180_Y1.5160.48
105_V127_Y1.5110.48
34_K181_L1.5100.48
264_S272_I1.5080.48
290_E296_G1.5050.48
287_E299_V1.4980.47
93_E150_H1.4900.47
90_I300_T1.4890.47
94_V164_D1.4850.47
281_R284_E1.4740.46
36_S42_P1.4700.46
24_I72_N1.4580.45
16_G69_K1.4500.45
182_S198_W1.4130.43
28_N174_N1.4090.43
121_F169_A1.4090.43
68_F163_G1.4040.43
204_E230_I1.3680.41
26_G155_K1.3580.41
235_E265_L1.3580.41
121_F165_K1.3540.41
47_F97_F1.3530.41
21_V34_K1.3500.40
99_K102_T1.3500.40
96_A173_D1.3490.40
94_V106_C1.3380.40
154_D178_V1.3360.40
197_A221_F1.3240.39
34_K119_D1.3110.39
251_Q277_N1.2940.38
43_L284_E1.2920.38
150_H155_K1.2910.38
118_N122_G1.2880.38
245_A268_Q1.2780.37
279_E284_E1.2700.37
248_Y258_E1.2570.36
28_N162_K1.2490.36
292_H301_E1.2470.36
85_M165_K1.2270.35
284_E298_K1.2260.35
29_N93_E1.2240.35
79_A85_M1.2210.35
20_K211_F1.2090.34
40_K88_T1.2090.34
36_S90_I1.2070.34
95_D114_I1.2040.34
288_I298_K1.2030.34
147_F161_P1.1980.34
91_V145_V1.1820.33
277_N281_R1.1760.33
184_N217_Y1.1740.33
75_L86_Y1.1710.33
117_G122_G1.1600.32
36_S88_T1.1560.32
251_Q264_S1.1510.32
263_N274_M1.1450.31
232_E260_L1.1350.31
74_Q86_Y1.1260.31
269_I287_E1.1250.31
108_Q112_E1.1250.31
115_K122_G1.1240.31
227_E230_I1.1190.30
197_A218_L1.1180.30
294_G298_K1.1180.30
55_A171_V1.1140.30
69_K104_Y1.1140.30
287_E294_G1.1100.30
88_T146_I1.1030.30
71_V75_L1.1010.30
235_E249_E1.0950.29
247_T261_D1.0900.29
273_G282_L1.0880.29
292_H299_V1.0870.29
154_D206_F1.0830.29
52_N70_K1.0830.29
245_A261_D1.0830.29
127_Y130_E1.0820.29
106_C113_R1.0780.29
249_E258_E1.0760.29
165_K169_A1.0750.29
95_D206_F1.0730.29
61_P264_S1.0700.29
24_I73_K1.0670.28
114_I210_R1.0650.28
16_G21_V1.0630.28
244_V264_S1.0630.28
147_F166_R1.0580.28
290_E293_L1.0540.28
260_L263_N1.0530.28
44_Y51_L1.0490.28
249_E276_L1.0480.28
268_Q272_I1.0430.27
39_M88_T1.0400.27
10_V60_M1.0390.27
31_G92_D1.0380.27
177_I193_I1.0370.27
31_G195_S1.0280.27
275_K281_R1.0190.27
186_V191_K1.0160.26
37_T221_F1.0130.26
35_Q303_S1.0130.26
74_Q218_L1.0100.26
235_E263_N1.0090.26
29_N150_H1.0080.26
46_P209_S1.0080.26
279_E286_N1.0070.26
111_V122_G0.9990.26
255_N268_Q0.9980.26
286_N298_K0.9930.26
242_G249_E0.9930.26
159_V203_E0.9930.26
264_S276_L0.9920.26
282_L287_E0.9880.25
245_A259_E0.9830.25
35_Q236_R0.9800.25
278_E281_R0.9760.25
268_Q291_K0.9730.25
242_G250_E0.9720.25
275_K283_E0.9650.25
46_P208_R0.9650.25
250_E253_Q0.9580.24
19_G54_I0.9580.24
111_V128_E0.9540.24
63_N273_G0.9500.24
24_I31_G0.9460.24
140_G287_E0.9450.24
18_E70_K0.9450.24
279_E285_V0.9420.24
65_W131_V0.9370.24
248_Y275_K0.9350.24
21_V144_T0.9340.24
257_S260_L0.9340.24
181_L221_F0.9320.23
280_G287_E0.9280.23
126_E169_A0.9270.23
29_N144_T0.9260.23
70_K73_K0.9250.23
117_G184_N0.9240.23
245_A260_L0.9170.23
33_T267_D0.9160.23
233_A260_L0.9130.23
244_V247_T0.9100.23
236_R268_Q0.9060.23
280_G284_E0.8940.22
107_E244_V0.8940.22
147_F150_H0.8920.22
289_T294_G0.8890.22
236_R288_I0.8860.22
23_T102_T0.8850.22
65_W197_A0.8830.22
154_D160_Y0.8830.22
248_Y266_M0.8800.22
70_K266_M0.8790.22
121_F171_V0.8780.22
274_M292_H0.8750.22
104_Y284_E0.8740.22
33_T67_D0.8720.21
288_I294_G0.8720.21
120_G179_L0.8650.21
91_V164_D0.8650.21
246_V269_I0.8630.21
128_E164_D0.8520.21
16_G33_T0.8510.21
34_K197_A0.8500.21
54_I150_H0.8500.21
63_N136_N0.8490.21
95_D172_I0.8470.21
24_I292_H0.8450.21
273_G279_E0.8390.20
154_D221_F0.8380.20
34_K150_H0.8370.20
209_S214_I0.8350.20
49_K168_L0.8330.20
242_G270_K0.8320.20
264_S267_D0.8310.20
88_T150_H0.8290.20
180_Y207_A0.8290.20
53_A74_Q0.8280.20
13_V33_T0.8280.20
247_T274_M0.8280.20
36_S40_K0.8210.20
40_K155_K0.8210.20
255_N284_E0.8200.20
24_I304_R0.8190.20
45_L293_L0.8180.20
24_I245_A0.8140.20
45_L157_G0.8140.20
31_G122_G0.8110.20
194_K258_E0.8080.20
86_Y169_A0.8020.19
28_N150_H0.7960.19
286_N304_R0.7950.19
162_K180_Y0.7900.19
106_C115_K0.7830.19
106_C154_D0.7810.19
260_L266_M0.7710.18
86_Y165_K0.7700.18
254_N272_I0.7690.18
252_K271_E0.7680.18
48_E129_T0.7640.18
34_K142_G0.7610.18
62_I68_F0.7570.18
10_V77_K0.7550.18
20_K231_I0.7540.18
29_N36_S0.7530.18
43_L71_V0.7530.18
75_L143_F0.7520.18
29_N88_T0.7480.18
28_N173_D0.7470.18
117_G229_A0.7470.18
284_E287_E0.7430.18
35_Q50_G0.7430.18
261_D287_E0.7390.18
253_Q286_N0.7380.18
174_N180_Y0.7370.17
279_E282_L0.7370.17
164_D187_D0.7360.17
264_S281_R0.7350.17
58_Q132_W0.7350.17
290_E297_V0.7330.17
50_G96_A0.7330.17
262_F266_M0.7320.17
264_S269_I0.7310.17
91_V159_V0.7300.17
285_V288_I0.7260.17
26_G32_K0.7250.17
151_A180_Y0.7220.17
257_S261_D0.7220.17
85_M225_N0.7210.17
134_E208_R0.7190.17
13_V159_V0.7180.17
285_V298_K0.7160.17
179_L199_L0.7160.17
34_K37_T0.7150.17
93_E208_R0.7140.17
42_P134_E0.7100.17
253_Q276_L0.7100.17
94_V110_D0.7090.17
153_E187_D0.7060.17
141_V233_A0.7040.17
49_K96_A0.6970.16
220_E304_R0.6960.16
65_W97_F0.6920.16
289_T297_V0.6900.16
268_Q286_N0.6900.16
271_E287_E0.6880.16
66_A171_V0.6870.16
108_Q261_D0.6820.16
262_F270_K0.6810.16
44_Y174_N0.6810.16
251_Q263_N0.6810.16
259_E272_I0.6800.16
246_V279_E0.6790.16
136_N149_A0.6770.16
271_E280_G0.6750.16
50_G149_A0.6640.16
272_I279_E0.6640.16
297_V302_C0.6600.15
136_N207_A0.6590.15
253_Q268_Q0.6580.15
141_V171_V0.6540.15
33_T51_L0.6530.15
256_A266_M0.6520.15
282_L285_V0.6500.15
69_K130_E0.6470.15
265_L278_E0.6450.15
293_L296_G0.6450.15
45_L71_V0.6440.15
26_G174_N0.6430.15
37_T44_Y0.6400.15
241_E248_Y0.6390.15
143_F208_R0.6380.15
125_K179_L0.6360.15
132_W136_N0.6360.15
46_P88_T0.6330.15
120_G199_L0.6320.15
40_K144_T0.6310.15
50_G67_D0.6310.15
236_R248_Y0.6260.15
257_S286_N0.6240.15
269_I274_M0.6180.14
16_G41_K0.6130.14
255_N259_E0.6120.14
11_S48_E0.6110.14
122_G142_G0.6100.14
172_I206_F0.6100.14
70_K89_I0.6100.14
181_L197_A0.6090.14
294_G299_V0.6060.14
21_V51_L0.6060.14
89_I243_I0.6050.14
42_P226_L0.6050.14
33_T141_V0.6050.14
85_M141_V0.6020.14
266_M275_K0.6010.14
50_G107_E0.6010.14
172_I178_V0.6000.14
269_I275_K0.6000.14
117_G206_F0.5990.14
55_A209_S0.5960.14
48_E161_P0.5930.14
66_A259_E0.5920.14
105_V125_K0.5900.14
283_E298_K0.5890.14
127_Y164_D0.5880.14
73_K257_S0.5870.14
120_G176_D0.5870.14
194_K220_E0.5860.14
180_Y205_H0.5850.14
48_E95_D0.5840.14
114_I129_T0.5840.14
144_T208_R0.5840.14
128_E167_V0.5840.14
258_E271_E0.5830.14
12_V60_M0.5830.14
78_N218_L0.5810.14
153_E165_K0.5810.14
232_E270_K0.5800.14
225_N244_V0.5780.14
293_L297_V0.5770.14
97_F197_A0.5760.14
12_V70_K0.5750.13
200_A216_T0.5730.13
11_S129_T0.5710.13
27_S55_A0.5700.13
46_P113_R0.5700.13
254_N268_Q0.5690.13
233_A262_F0.5690.13
116_D124_W0.5660.13
21_V150_H0.5630.13
225_N254_N0.5620.13
17_L54_I0.5610.13
102_T111_V0.5580.13
235_E241_E0.5580.13
281_R288_I0.5570.13
11_S14_A0.5560.13
227_E231_I0.5560.13
28_N184_N0.5550.13
24_I266_M0.5510.13
99_K104_Y0.5510.13
113_R152_A0.5510.13
170_P227_E0.5500.13
232_E242_G0.5500.13
25_Y29_N0.5480.13
281_R286_N0.5470.13
102_T109_Y0.5460.13
74_Q108_Q0.5440.13
271_E299_V0.5410.13
261_D265_L0.5400.13
252_K255_N0.5400.13
164_D167_V0.5390.13
250_E280_G0.5380.13
66_A232_E0.5370.13
283_E291_K0.5340.13
150_H176_D0.5330.13
10_V85_M0.5330.13
118_N129_T0.5330.13
51_L174_N0.5320.13
19_G136_N0.5310.13
296_G302_C0.5310.13
121_F164_D0.5300.13
116_D167_V0.5290.12
56_G160_Y0.5290.12
105_V267_D0.5280.12
249_E281_R0.5280.12
253_Q257_S0.5270.12
121_F128_E0.5250.12
170_P204_E0.5240.12
247_T265_L0.5240.12
105_V122_G0.5240.12
18_E171_V0.5230.12
153_E160_Y0.5220.12
222_T259_E0.5180.12
99_K225_N0.5170.12
251_Q266_M0.5160.12
174_N182_S0.5150.12
98_A143_F0.5150.12
90_I150_H0.5140.12
254_N264_S0.5100.12
95_D118_N0.5070.12
158_K193_I0.5040.12
272_I276_L0.5040.12
45_L62_I0.5020.12
34_K93_E0.5020.12
274_M291_K0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ppfA 1 0.7709 98.9 0.866 Contact Map
3hr8A 1 0.8607 98.7 0.877 Contact Map
1n0wA 1 0.5387 98.6 0.878 Contact Map
3ldaA 1 0.5573 98.6 0.879 Contact Map
2cvhA 1 0.6068 98.6 0.88 Contact Map
2q6tA 1 0.6285 98.6 0.88 Contact Map
1u94A 3 0.7585 98.5 0.881 Contact Map
2z43A 1 0.5511 98.5 0.884 Contact Map
3bgwA 3 0.644 98.4 0.885 Contact Map
1pznA 5 0.5697 98.4 0.885 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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