GREMLIN Database
YORK - Putative SPBc2 prophage-derived single-strand DNA-specific exonuclease YorK
UniProt: O31903 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 576 (522)
Sequences: 3306 (2416)
Seq/√Len: 105.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
109_I134_A3.6151.00
47_N50_K3.4371.00
390_I398_I3.2901.00
550_E555_K3.2691.00
54_C141_E3.2011.00
132_H142_I3.1591.00
54_C63_N3.1551.00
429_N432_L3.0281.00
84_N231_H2.9841.00
412_E426_K2.8621.00
77_T205_G2.8521.00
112_I138_R2.7201.00
14_D469_Q2.7161.00
488_I544_G2.7141.00
174_T205_G2.7111.00
132_H144_V2.6791.00
280_A292_K2.6771.00
409_G436_V2.6511.00
468_L555_K2.6291.00
501_L519_I2.6201.00
46_N163_Q2.5441.00
85_Y183_C2.4901.00
397_F400_D2.4621.00
86_I91_P2.4501.00
66_F111_T2.4431.00
506_K511_F2.4381.00
81_I176_A2.4351.00
133_E156_H2.3711.00
284_S292_K2.3301.00
119_V140_T2.3261.00
330_K367_E2.3151.00
541_N565_E2.3111.00
66_F116_V2.2991.00
63_N117_D2.2481.00
47_N163_Q2.2151.00
69_V79_S2.2081.00
202_V221_F2.2051.00
396_G441_F2.1841.00
65_L91_P2.1831.00
377_N427_R2.1801.00
456_E489_T2.1601.00
163_Q166_P2.1261.00
133_E137_K2.1181.00
55_L120_I2.1161.00
453_V543_I2.1011.00
316_A319_K2.0921.00
520_R523_S2.0831.00
136_N156_H2.0601.00
346_V374_L2.0311.00
375_A386_L2.0311.00
176_A205_G2.0241.00
386_L430_L2.0231.00
545_K562_Y2.0221.00
51_A159_V2.0141.00
504_K511_F2.0041.00
44_K169_S2.0021.00
239_K294_G1.9901.00
347_Y377_N1.9391.00
343_V437_L1.9301.00
84_N285_K1.8891.00
83_I87_K1.8801.00
149_E162_N1.8661.00
207_I254_T1.8551.00
97_Y100_Q1.8481.00
208_A259_N1.8321.00
426_K429_N1.8231.00
261_L312_G1.8201.00
312_G316_A1.7891.00
105_H134_A1.7881.00
170_N214_R1.7871.00
134_A137_K1.7801.00
284_S293_R1.7611.00
432_L436_V1.7581.00
435_K439_E1.7471.00
57_R61_N1.7431.00
64_K92_K1.7421.00
268_V321_I1.7311.00
324_A328_E1.7171.00
346_V364_L1.7111.00
63_N141_E1.6911.00
46_N166_P1.6881.00
59_L91_P1.6841.00
385_I412_E1.6801.00
508_T517_E1.6791.00
105_H130_E1.6671.00
432_L435_K1.6561.00
390_I421_A1.6541.00
173_L177_G1.6541.00
166_P171_K1.6511.00
425_I433_V1.6501.00
212_D480_K1.6491.00
200_D231_H1.6401.00
54_C58_H1.6321.00
134_A138_R1.6151.00
378_D383_K1.6091.00
404_E440_K1.6081.00
433_V437_L1.6011.00
410_L429_N1.5961.00
549_N558_Q1.5891.00
548_A555_K1.5881.00
343_V438_N1.5551.00
467_I557_P1.5431.00
386_L425_I1.5421.00
53_D189_K1.5351.00
203_S225_G1.5351.00
97_Y270_S1.5221.00
458_P461_R1.5201.00
377_N386_L1.5191.00
55_L182_F1.5171.00
73_V204_I1.5161.00
375_A430_L1.5161.00
224_E227_K1.5131.00
145_I175_G1.5101.00
328_E348_I1.5061.00
109_I113_P1.5031.00
40_I217_E1.5011.00
330_K334_E1.4901.00
341_N438_N1.4821.00
176_A202_V1.4791.00
489_T541_N1.4771.00
154_S158_I1.4761.00
56_I190_L1.4741.00
82_I179_A1.4731.00
504_K508_T1.4721.00
95_I279_R1.4711.00
207_I222_M1.4611.00
375_A423_F1.4611.00
549_N556_T1.4601.00
45_L159_V1.4471.00
58_H63_N1.4351.00
181_K217_E1.4301.00
323_D327_V1.4241.00
30_L38_S1.4201.00
54_C143_I1.4101.00
384_D427_R1.4071.00
105_H109_I1.4021.00
43_S49_D1.3951.00
40_I215_N1.3911.00
49_D53_D1.3771.00
373_L423_F1.3741.00
48_I52_A1.3661.00
11_Y28_P1.3601.00
51_A143_I1.3430.99
56_I189_K1.3380.99
292_K295_Q1.3360.99
51_A182_F1.3330.99
66_F94_N1.3280.99
445_N449_D1.3280.99
240_K312_G1.3270.99
410_L436_V1.3190.99
108_F119_V1.3160.99
542_V561_I1.3130.99
255_Q259_N1.3120.99
67_V83_I1.3100.99
518_Y561_I1.3080.99
457_I486_I1.3060.99
341_N434_N1.3060.99
181_K184_Q1.3050.99
16_L469_Q1.3040.99
344_L368_Y1.3020.99
286_E292_K1.2990.99
238_F249_K1.2990.99
547_K560_E1.2980.99
396_G401_F1.2940.99
265_A311_L1.2860.99
362_N365_A1.2750.99
485_L543_I1.2730.99
127_S151_E1.2650.99
158_I163_Q1.2640.99
485_L562_Y1.2620.99
364_L372_V1.2610.99
55_L143_I1.2600.99
511_F542_V1.2560.99
83_I283_L1.2540.99
320_R324_A1.2540.99
403_K408_T1.2530.99
332_R348_I1.2490.99
511_F518_Y1.2480.99
431_I434_N1.2480.99
439_E443_D1.2380.99
235_K287_K1.2250.99
251_I474_K1.2210.99
238_F245_T1.2200.99
43_S185_A1.2180.99
82_I182_F1.2140.99
57_R193_N1.2110.99
88_K197_Q1.2110.99
87_K285_K1.2100.99
243_F253_N1.2060.99
364_L368_Y1.1930.99
412_E424_A1.1880.99
520_R561_I1.1880.99
331_N335_E1.1830.99
354_K387_S1.1780.99
180_Y202_V1.1780.99
145_I178_M1.1720.99
52_A189_K1.1710.99
440_K444_I1.1700.99
295_Q299_E1.1680.99
250_S253_N1.1610.98
129_F153_V1.1570.98
349_E377_N1.1550.98
505_N511_F1.1530.98
46_N165_S1.1520.98
80_S283_L1.1500.98
52_A186_I1.1480.98
101_D107_I1.1430.98
145_I182_F1.1390.98
204_I258_I1.1390.98
236_K297_E1.1350.98
59_L65_L1.1340.98
64_K117_D1.1330.98
58_H118_L1.1320.98
76_Y262_I1.1300.98
55_L118_L1.1260.98
397_F418_P1.1250.98
207_I255_Q1.1190.98
52_A185_A1.1190.98
364_L374_L1.1170.98
85_Y187_D1.1160.98
119_V135_L1.1160.98
508_T511_F1.1140.98
42_Y48_I1.1130.98
48_I185_A1.1120.98
386_L427_R1.1050.98
487_A543_I1.1010.98
112_I140_T1.1010.98
233_L281_F1.1000.98
129_F151_E1.1000.98
52_A56_I1.0990.98
273_E299_E1.0990.98
204_I254_T1.0980.98
342_K438_N1.0980.98
30_L215_N1.0980.98
262_I282_L1.0930.98
43_S48_I1.0900.98
517_E556_T1.0870.98
464_K548_A1.0860.98
232_P236_K1.0850.98
77_T174_T1.0840.98
135_L142_I1.0830.98
446_I449_D1.0820.98
327_V331_N1.0820.98
40_I169_S1.0770.98
238_F258_I1.0760.98
492_E539_V1.0760.98
34_V223_N1.0730.97
135_L140_T1.0710.97
500_H504_K1.0710.97
110_D114_D1.0570.97
292_K296_S1.0550.97
118_L141_E1.0540.97
47_N165_S1.0510.97
105_H131_E1.0510.97
399_K414_V1.0480.97
238_F243_F1.0470.97
39_V220_Y1.0440.97
56_I60_N1.0420.97
13_F16_L1.0390.97
453_V487_A1.0390.97
544_G559_I1.0360.97
57_R63_N1.0360.97
174_T206_N1.0310.97
64_K94_N1.0300.97
494_E512_K1.0260.97
177_G205_G1.0190.97
29_K33_N1.0170.96
67_V122_P1.0140.96
77_T176_A1.0130.96
99_I354_K1.0070.96
471_D474_K1.0050.96
81_I202_V1.0030.96
437_L441_F1.0020.96
488_I491_L1.0010.96
328_E352_L1.0000.96
106_G109_I0.9990.96
322_V363_Q0.9950.96
333_I368_Y0.9920.96
126_S158_I0.9890.96
54_C118_L0.9860.96
299_E313_N0.9840.96
73_V208_A0.9830.96
33_N472_G0.9810.96
440_K443_D0.9810.96
321_I356_L0.9800.96
465_E468_L0.9770.96
168_Y181_K0.9770.96
241_Q261_L0.9760.96
126_S150_C0.9750.96
36_Q224_E0.9750.96
436_V439_E0.9710.95
492_E512_K0.9710.95
130_E133_E0.9700.95
430_L434_N0.9680.95
347_Y386_L0.9650.95
17_A21_K0.9650.95
412_E425_I0.9620.95
223_N227_K0.9590.95
330_K368_Y0.9580.95
244_S247_G0.9570.95
401_F404_E0.9560.95
58_H141_E0.9530.95
483_E545_K0.9460.95
313_N317_K0.9450.95
436_V440_K0.9450.95
540_I564_L0.9430.95
388_G423_F0.9380.94
373_L390_I0.9370.94
55_L186_I0.9370.94
373_L402_K0.9360.94
460_K513_H0.9350.94
124_A128_Q0.9330.94
128_Q131_E0.9320.94
210_S479_Y0.9320.94
342_K442_K0.9320.94
224_E228_K0.9320.94
213_S222_M0.9320.94
467_I548_A0.9310.94
154_S163_Q0.9310.94
23_R454_D0.9290.94
405_L440_K0.9290.94
509_V518_Y0.9280.94
519_I558_Q0.9270.94
395_K418_P0.9250.94
390_I423_F0.9220.94
236_K239_K0.9200.94
14_D461_R0.9190.94
68_Q107_I0.9170.94
31_F481_V0.9150.94
88_K198_F0.9140.94
101_D110_D0.9130.94
325_A356_L0.9120.94
133_E136_N0.9110.94
36_Q39_V0.9080.93
230_K247_G0.9070.93
45_L48_I0.9040.93
294_G298_T0.9020.93
36_Q199_L0.9010.93
550_E553_G0.9010.93
35_D38_S0.9000.93
79_S279_R0.8950.93
40_I181_K0.8930.93
343_V441_F0.8900.93
81_I198_F0.8900.93
62_K92_K0.8900.93
94_N114_D0.8860.93
499_E517_E0.8860.93
411_F423_F0.8860.93
469_Q472_G0.8830.93
467_I546_A0.8810.92
83_I93_A0.8800.92
109_I138_R0.8780.92
121_I145_I0.8770.92
108_F135_L0.8720.92
135_L138_R0.8720.92
338_L341_N0.8720.92
13_F17_A0.8710.92
177_G211_A0.8670.92
505_N508_T0.8670.92
229_I254_T0.8660.92
85_Y89_I0.8640.92
254_T259_N0.8630.92
189_K193_N0.8600.91
404_E443_D0.8590.91
438_N442_K0.8590.91
373_L433_V0.8590.91
405_L411_F0.8590.91
405_L436_V0.8580.91
298_T313_N0.8570.91
76_Y271_S0.8570.91
36_Q220_Y0.8560.91
396_G445_N0.8560.91
253_N257_F0.8550.91
82_I183_C0.8540.91
410_L432_L0.8510.91
18_T22_N0.8510.91
71_S103_K0.8510.91
331_N334_E0.8490.91
284_S296_S0.8470.91
401_F440_K0.8460.91
273_E314_L0.8460.91
199_L202_V0.8430.91
41_H48_I0.8430.91
19_I455_F0.8390.90
404_E444_I0.8390.90
431_I435_K0.8360.90
69_V95_I0.8350.90
220_Y224_E0.8350.90
281_F296_S0.8310.90
67_V82_I0.8300.90
491_L542_V0.8220.90
168_Y217_E0.8180.89
272_E280_A0.8170.89
80_S279_R0.8150.89
76_Y274_K0.8150.89
240_K298_T0.8120.89
469_Q473_Y0.8090.89
17_A28_P0.8090.89
132_H156_H0.8080.89
345_I433_V0.8070.89
84_N198_F0.8040.89
54_C57_R0.8020.88
239_K244_S0.8010.88
464_K557_P0.8010.88
410_L433_V0.8000.88
287_K294_G0.7980.88
53_D57_R0.7970.88
356_L360_V0.7940.88
547_K558_Q0.7910.88
325_A360_V0.7910.88
434_N438_N0.7900.88
493_I540_I0.7880.88
41_H44_K0.7880.88
126_S175_G0.7870.87
492_E510_K0.7850.87
94_N116_V0.7840.87
25_I28_P0.7830.87
160_V163_Q0.7820.87
549_N555_K0.7810.87
279_R283_L0.7780.87
160_V166_P0.7780.87
326_G330_K0.7740.87
44_K48_I0.7710.86
180_Y221_F0.7700.86
39_V180_Y0.7690.86
459_A491_L0.7680.86
365_A419_N0.7660.86
468_L548_A0.7650.86
510_K517_E0.7640.86
464_K555_K0.7600.86
49_D189_K0.7590.85
402_K411_F0.7590.85
345_I430_L0.7590.85
265_A274_K0.7580.85
183_C187_D0.7570.85
345_I434_N0.7570.85
252_Q257_F0.7560.85
39_V221_F0.7560.85
170_N215_N0.7550.85
206_N222_M0.7530.85
493_I531_L0.7520.85
200_D228_K0.7510.85
545_K560_E0.7500.85
365_A372_V0.7490.85
81_I85_Y0.7460.85
328_E331_N0.7460.85
40_I168_Y0.7460.85
204_I234_L0.7450.84
332_R346_V0.7450.84
490_D541_N0.7410.84
40_I44_K0.7390.84
354_K378_D0.7390.84
236_K294_G0.7390.84
467_I471_D0.7350.84
175_G178_M0.7350.84
179_A182_F0.7340.84
240_K297_E0.7330.83
385_I424_A0.7320.83
204_I229_I0.7300.83
57_R189_K0.7300.83
79_S95_I0.7300.83
227_K230_K0.7280.83
317_K320_R0.7270.83
51_A118_L0.7270.83
172_T212_D0.7260.83
341_N370_K0.7260.83
162_N171_K0.7250.83
517_E558_Q0.7250.83
77_T201_L0.7250.83
111_T116_V0.7240.83
99_I353_D0.7240.83
18_T461_R0.7240.83
82_I120_I0.7240.83
375_A425_I0.7230.83
334_E368_Y0.7230.83
325_A352_L0.7220.83
250_S474_K0.7160.82
516_I559_I0.7150.82
471_D548_A0.7130.82
201_L231_H0.7130.82
159_V182_F0.7130.82
445_N450_I0.7120.82
462_L557_P0.7100.81
509_V561_I0.7100.81
232_P287_K0.7100.81
64_K116_V0.7100.81
107_I111_T0.7090.81
411_F433_V0.7090.81
455_F486_I0.7080.81
369_K395_K0.7070.81
329_I364_L0.7070.81
55_L65_L0.7060.81
170_N217_E0.7060.81
71_S98_R0.7050.81
54_C117_D0.7040.81
108_F134_A0.7030.81
423_F437_L0.7020.81
293_R297_E0.7000.81
39_V202_V0.6980.80
80_S201_L0.6980.80
399_K403_K0.6980.80
281_F297_E0.6980.80
95_I362_N0.6980.80
357_T390_I0.6960.80
319_K323_D0.6960.80
67_V93_A0.6920.80
126_S154_S0.6900.80
235_K239_K0.6890.80
145_I179_A0.6880.79
27_D30_L0.6860.79
377_N430_L0.6820.79
112_I115_D0.6810.79
240_K294_G0.6780.78
206_N218_T0.6780.78
349_E427_R0.6750.78
43_S188_E0.6750.78
20_L473_Y0.6730.78
232_P285_K0.6720.78
329_I352_L0.6700.78
465_E469_Q0.6700.78
237_L297_E0.6690.77
315_K318_Q0.6680.77
71_S102_G0.6650.77
126_S145_I0.6650.77
284_S287_K0.6640.77
97_Y269_G0.6640.77
87_K283_L0.6640.77
456_E488_I0.6640.77
353_D359_L0.6640.77
457_I462_L0.6630.77
519_I560_E0.6610.77
120_I143_I0.6580.76
464_K467_I0.6560.76
163_Q171_K0.6560.76
343_V373_L0.6560.76
474_K477_W0.6550.76
441_F445_N0.6540.76
174_T177_G0.6530.76
180_Y184_Q0.6510.76
90_C93_A0.6500.75
333_I337_S0.6490.75
486_I544_G0.6480.75
189_K192_K0.6470.75
68_Q124_A0.6470.75
273_E296_S0.6470.75
512_K515_D0.6450.75
395_K449_D0.6440.75
85_Y198_F0.6430.75
244_S248_D0.6430.75
328_E350_G0.6420.75
487_A541_N0.6420.75
115_D140_T0.6410.74
500_H506_K0.6400.74
521_F560_E0.6380.74
501_L505_N0.6370.74
507_T518_Y0.6370.74
212_D479_Y0.6370.74
242_E316_A0.6370.74
95_I271_S0.6340.74
243_F257_F0.6340.74
373_L398_I0.6330.74
129_F156_H0.6330.74
280_A296_S0.6320.73
126_S157_A0.6320.73
130_E134_A0.6320.73
122_P145_I0.6320.73
506_K513_H0.6310.73
398_I421_A0.6310.73
210_S362_N0.6310.73
234_L238_F0.6310.73
501_L521_F0.6310.73
56_I186_I0.6280.73
392_G421_A0.6280.73
352_L357_T0.6280.73
179_A183_C0.6270.73
456_E487_A0.6270.73
26_E30_L0.6260.73
69_V122_P0.6260.73
43_S52_A0.6260.73
79_S179_A0.6240.72
385_I426_K0.6240.72
45_L168_Y0.6230.72
98_R102_G0.6230.72
154_S157_A0.6210.72
466_F470_L0.6160.72
56_I59_L0.6160.72
236_K293_R0.6160.72
40_I170_N0.6140.71
427_R430_L0.6140.71
322_V356_L0.6120.71
101_D106_G0.6120.71
253_N259_N0.6120.71
158_I161_N0.6110.71
116_V140_T0.6100.71
172_T211_A0.6100.71
84_N87_K0.6090.71
232_P235_K0.6080.71
322_V352_L0.6080.71
499_E508_T0.6070.70
121_I175_G0.6070.70
45_L166_P0.6070.70
196_E224_E0.6060.70
112_I117_D0.6060.70
459_A488_I0.6060.70
150_C160_V0.6060.70
108_F111_T0.6050.70
126_S160_V0.6050.70
333_I338_L0.6030.70
274_K279_R0.6020.70
194_E197_Q0.6010.70
16_L20_L0.6000.70
63_N118_L0.6000.70
229_I249_K0.5980.69
266_I415_E0.5960.69
500_H524_D0.5940.69
493_I498_I0.5930.69
124_A127_S0.5930.69
488_I546_A0.5920.69
409_G432_L0.5920.69
446_I450_I0.5920.69
344_L372_V0.5910.68
32_V473_Y0.5910.68
133_E153_V0.5910.68
314_L317_K0.5900.68
44_K168_Y0.5900.68
180_Y196_E0.5890.68
441_F444_I0.5890.68
230_K238_F0.5880.68
369_K450_I0.5880.68
269_G273_E0.5870.68
177_G180_Y0.5870.68
152_R164_L0.5850.68
68_Q111_T0.5840.67
271_S274_K0.5830.67
65_L89_I0.5830.67
57_R141_E0.5820.67
233_L297_E0.5810.67
110_D113_P0.5810.67
46_N171_K0.5810.67
346_V372_V0.5810.67
334_E367_E0.5810.67
121_I142_I0.5800.67
500_H528_F0.5780.67
411_F425_I0.5780.67
196_E228_K0.5770.67
329_I346_V0.5770.67
18_T455_F0.5770.67
350_G377_N0.5760.66
122_P179_A0.5730.66
85_Y186_I0.5720.66
153_V156_H0.5720.66
252_Q483_E0.5710.66
502_G505_N0.5710.66
280_A284_S0.5710.66
295_Q298_T0.5710.66
269_G299_E0.5700.66
11_Y17_A0.5700.66
457_I546_A0.5690.65
201_L282_L0.5670.65
325_A348_I0.5660.65
80_S200_D0.5650.65
16_L466_F0.5650.65
345_I375_A0.5650.65
337_S340_A0.5640.65
73_V124_A0.5640.65
78_S174_T0.5640.65
356_L359_L0.5620.65
122_P175_G0.5610.64
362_N366_E0.5610.64
403_K414_V0.5600.64
505_N522_K0.5600.64
208_A254_T0.5600.64
66_F114_D0.5600.64
86_I89_I0.5590.64
229_I238_F0.5580.64
45_L163_Q0.5570.64
162_N172_T0.5550.64
258_I281_F0.5530.63
84_N283_L0.5530.63
73_V77_T0.5520.63
383_K427_R0.5520.63
55_L183_C0.5500.63
229_I258_I0.5500.63
11_Y29_K0.5500.63
269_G314_L0.5500.63
176_A180_Y0.5490.63
174_T211_A0.5490.63
233_L237_L0.5480.63
151_E399_K0.5480.63
507_T524_D0.5470.62
69_V475_D0.5470.62
459_A513_H0.5470.62
500_H525_E0.5470.62
501_L504_K0.5460.62
385_I413_F0.5460.62
19_I22_N0.5460.62
187_D194_E0.5460.62
78_S122_P0.5460.62
348_I376_R0.5460.62
320_R323_D0.5450.62
239_K287_K0.5440.62
197_Q228_K0.5430.62
498_I509_V0.5430.62
143_I182_F0.5430.62
529_N532_T0.5430.62
402_K414_V0.5430.62
322_V362_N0.5420.62
107_I386_L0.5420.62
109_I137_K0.5420.62
112_I134_A0.5410.62
364_L551_Y0.5410.62
121_I178_M0.5400.61
168_Y184_Q0.5400.61
488_I559_I0.5390.61
211_A479_Y0.5380.61
393_Y449_D0.5380.61
409_G412_E0.5360.61
211_A264_A0.5350.61
118_L140_T0.5340.61
299_E314_L0.5340.61
150_C164_L0.5330.60
494_E510_K0.5310.60
501_L508_T0.5310.60
108_F112_I0.5300.60
241_Q312_G0.5290.60
34_V220_Y0.5290.60
332_R335_E0.5290.60
38_S220_Y0.5280.60
254_T258_I0.5280.60
413_F424_A0.5280.60
40_I184_Q0.5280.60
149_E399_K0.5280.60
338_L434_N0.5280.60
393_Y450_I0.5270.60
183_C198_F0.5270.60
375_A411_F0.5260.59
188_E192_K0.5260.59
132_H158_I0.5250.59
80_S84_N0.5240.59
506_K517_E0.5240.59
463_R546_A0.5230.59
200_D225_G0.5230.59
112_I135_L0.5220.59
411_F429_N0.5220.59
261_L297_E0.5220.59
518_Y559_I0.5190.58
76_Y265_A0.5190.58
103_K266_I0.5190.58
109_I112_I0.5190.58
184_Q217_E0.5170.58
494_E498_I0.5160.58
237_L258_I0.5160.58
543_I563_E0.5150.58
377_N425_I0.5140.58
83_I86_I0.5140.58
238_F253_N0.5130.58
352_L355_S0.5130.58
73_V174_T0.5130.58
68_Q101_D0.5110.57
261_L352_L0.5110.57
33_N38_S0.5100.57
548_A557_P0.5100.57
243_F247_G0.5090.57
489_T539_V0.5090.57
78_S175_G0.5090.57
517_E521_F0.5080.57
236_K240_K0.5080.57
346_V352_L0.5080.57
108_F140_T0.5070.57
181_K187_D0.5070.57
524_D528_F0.5070.57
488_I513_H0.5070.57
494_E497_Q0.5070.57
26_E29_K0.5070.57
245_T248_D0.5070.57
187_D195_A0.5060.57
552_K556_T0.5060.57
500_H561_I0.5050.56
68_Q168_Y0.5050.56
427_R431_I0.5030.56
230_K245_T0.5030.56
408_T414_V0.5000.56
477_W484_P0.5000.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zxrA 1 0.8247 100 0.322 Contact Map
4ls9A 2 0.5174 100 0.814 Contact Map
3devA 2 0.5208 100 0.828 Contact Map
4py9A 2 0.5417 100 0.836 Contact Map
1wpnA 2 0.2969 99.4 0.914 Contact Map
2hawA 2 0.5017 98.3 0.944 Contact Map
1k20A 2 0.4601 97.9 0.949 Contact Map
4rpaA 3 0.4965 97.9 0.95 Contact Map
2eb0A 2 0.4809 97.1 0.956 Contact Map
2qb7A 1 0.5573 96.3 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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