YORK - BACSU - GREMLIN Contacts

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YORK - Putative SPBc2 prophage-derived single-strand DNA-specific exonuclease YorK

UniProt:	O31903	Sequences: MEYRLIGDNDYNFDPLATILKNRGIEDPKLFVNVDQSSVIHYSKLNNIDKAADCLIRHLNNKNKLFVQVDSDVDGYTSSSIIINYIKKICPKANIHYRIQDGKEHGIFIDTIPDDVDLVIIPDAGSSQFEEHEALNKRGTEIIVIDHHECERVSEHAIVVNNQLSPNYSNKTLTGAGMAYKFCQAIDEKLNKNEAEQFLDLVSIGNIADSADSRNLETRYFMNEGLKKIKHPLLKKLFKKQEFSTKGDKSIQNTQFFINPLINAAIRVGSSEEKDQMMRAFLLSKEKVPYKKRGQSETELVSIHEDTVRILGNLKAKQKRIVDAAGVEIKNRIEEKSLTANKVLIVYIEGILDKSLTGLVANQLAEEYKKPVLLARNDPEKGKDILSGSIRGYDKGFIKDFKKELIDTGLFEFVEGHPNAAGFAIKRQNLILVNKVLNEKFKDINIEEDIQNVDFEIPAKRLRKEFILQLDGYKDYWGYKVEEPLIAITDLEIEVEQIEHLGKKNKTTVKFKHGDIEYIRFKSDENYFNQLTASNGTLVINVIGKAKANEYKGKKTPQIEIYELEVVRTKQKELVF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	576 (522)
Sequences:	3306 (2416)
Seq/√Len:	105.8

ECOLI - RECJ
BACSU - YORK RECJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
109_I	134_A	3.615	1.00
47_N	50_K	3.437	1.00
390_I	398_I	3.290	1.00
550_E	555_K	3.269	1.00
54_C	141_E	3.201	1.00
132_H	142_I	3.159	1.00
54_C	63_N	3.155	1.00
429_N	432_L	3.028	1.00
84_N	231_H	2.984	1.00
412_E	426_K	2.862	1.00
77_T	205_G	2.852	1.00
112_I	138_R	2.720	1.00
14_D	469_Q	2.716	1.00
488_I	544_G	2.714	1.00
174_T	205_G	2.711	1.00
132_H	144_V	2.679	1.00
280_A	292_K	2.677	1.00
409_G	436_V	2.651	1.00
468_L	555_K	2.629	1.00
501_L	519_I	2.620	1.00
46_N	163_Q	2.544	1.00
85_Y	183_C	2.490	1.00
397_F	400_D	2.462	1.00
86_I	91_P	2.450	1.00
66_F	111_T	2.443	1.00
506_K	511_F	2.438	1.00
81_I	176_A	2.435	1.00
133_E	156_H	2.371	1.00
284_S	292_K	2.330	1.00
119_V	140_T	2.326	1.00
330_K	367_E	2.315	1.00
541_N	565_E	2.311	1.00
66_F	116_V	2.299	1.00
63_N	117_D	2.248	1.00
47_N	163_Q	2.215	1.00
69_V	79_S	2.208	1.00
202_V	221_F	2.205	1.00
396_G	441_F	2.184	1.00
65_L	91_P	2.183	1.00
377_N	427_R	2.180	1.00
456_E	489_T	2.160	1.00
163_Q	166_P	2.126	1.00
133_E	137_K	2.118	1.00
55_L	120_I	2.116	1.00
453_V	543_I	2.101	1.00
316_A	319_K	2.092	1.00
520_R	523_S	2.083	1.00
136_N	156_H	2.060	1.00
346_V	374_L	2.031	1.00
375_A	386_L	2.031	1.00
176_A	205_G	2.024	1.00
386_L	430_L	2.023	1.00
545_K	562_Y	2.022	1.00
51_A	159_V	2.014	1.00
504_K	511_F	2.004	1.00
44_K	169_S	2.002	1.00
239_K	294_G	1.990	1.00
347_Y	377_N	1.939	1.00
343_V	437_L	1.930	1.00
84_N	285_K	1.889	1.00
83_I	87_K	1.880	1.00
149_E	162_N	1.866	1.00
207_I	254_T	1.855	1.00
97_Y	100_Q	1.848	1.00
208_A	259_N	1.832	1.00
426_K	429_N	1.823	1.00
261_L	312_G	1.820	1.00
312_G	316_A	1.789	1.00
105_H	134_A	1.788	1.00
170_N	214_R	1.787	1.00
134_A	137_K	1.780	1.00
284_S	293_R	1.761	1.00
432_L	436_V	1.758	1.00
435_K	439_E	1.747	1.00
57_R	61_N	1.743	1.00
64_K	92_K	1.742	1.00
268_V	321_I	1.731	1.00
324_A	328_E	1.717	1.00
346_V	364_L	1.711	1.00
63_N	141_E	1.691	1.00
46_N	166_P	1.688	1.00
59_L	91_P	1.684	1.00
385_I	412_E	1.680	1.00
508_T	517_E	1.679	1.00
105_H	130_E	1.667	1.00
432_L	435_K	1.656	1.00
390_I	421_A	1.654	1.00
173_L	177_G	1.654	1.00
166_P	171_K	1.651	1.00
425_I	433_V	1.650	1.00
212_D	480_K	1.649	1.00
200_D	231_H	1.640	1.00
54_C	58_H	1.632	1.00
134_A	138_R	1.615	1.00
378_D	383_K	1.609	1.00
404_E	440_K	1.608	1.00
433_V	437_L	1.601	1.00
410_L	429_N	1.596	1.00
549_N	558_Q	1.589	1.00
548_A	555_K	1.588	1.00
343_V	438_N	1.555	1.00
467_I	557_P	1.543	1.00
386_L	425_I	1.542	1.00
53_D	189_K	1.535	1.00
203_S	225_G	1.535	1.00
97_Y	270_S	1.522	1.00
458_P	461_R	1.520	1.00
377_N	386_L	1.519	1.00
55_L	182_F	1.517	1.00
73_V	204_I	1.516	1.00
375_A	430_L	1.516	1.00
224_E	227_K	1.513	1.00
145_I	175_G	1.510	1.00
328_E	348_I	1.506	1.00
109_I	113_P	1.503	1.00
40_I	217_E	1.501	1.00
330_K	334_E	1.490	1.00
341_N	438_N	1.482	1.00
176_A	202_V	1.479	1.00
489_T	541_N	1.477	1.00
154_S	158_I	1.476	1.00
56_I	190_L	1.474	1.00
82_I	179_A	1.473	1.00
504_K	508_T	1.472	1.00
95_I	279_R	1.471	1.00
207_I	222_M	1.461	1.00
375_A	423_F	1.461	1.00
549_N	556_T	1.460	1.00
45_L	159_V	1.447	1.00
58_H	63_N	1.435	1.00
181_K	217_E	1.430	1.00
323_D	327_V	1.424	1.00
30_L	38_S	1.420	1.00
54_C	143_I	1.410	1.00
384_D	427_R	1.407	1.00
105_H	109_I	1.402	1.00
43_S	49_D	1.395	1.00
40_I	215_N	1.391	1.00
49_D	53_D	1.377	1.00
373_L	423_F	1.374	1.00
48_I	52_A	1.366	1.00
11_Y	28_P	1.360	1.00
51_A	143_I	1.343	0.99
56_I	189_K	1.338	0.99
292_K	295_Q	1.336	0.99
51_A	182_F	1.333	0.99
66_F	94_N	1.328	0.99
445_N	449_D	1.328	0.99
240_K	312_G	1.327	0.99
410_L	436_V	1.319	0.99
108_F	119_V	1.316	0.99
542_V	561_I	1.313	0.99
255_Q	259_N	1.312	0.99
67_V	83_I	1.310	0.99
518_Y	561_I	1.308	0.99
457_I	486_I	1.306	0.99
341_N	434_N	1.306	0.99
181_K	184_Q	1.305	0.99
16_L	469_Q	1.304	0.99
344_L	368_Y	1.302	0.99
286_E	292_K	1.299	0.99
238_F	249_K	1.299	0.99
547_K	560_E	1.298	0.99
396_G	401_F	1.294	0.99
265_A	311_L	1.286	0.99
362_N	365_A	1.275	0.99
485_L	543_I	1.273	0.99
127_S	151_E	1.265	0.99
158_I	163_Q	1.264	0.99
485_L	562_Y	1.262	0.99
364_L	372_V	1.261	0.99
55_L	143_I	1.260	0.99
511_F	542_V	1.256	0.99
83_I	283_L	1.254	0.99
320_R	324_A	1.254	0.99
403_K	408_T	1.253	0.99
332_R	348_I	1.249	0.99
511_F	518_Y	1.248	0.99
431_I	434_N	1.248	0.99
439_E	443_D	1.238	0.99
235_K	287_K	1.225	0.99
251_I	474_K	1.221	0.99
238_F	245_T	1.220	0.99
43_S	185_A	1.218	0.99
82_I	182_F	1.214	0.99
57_R	193_N	1.211	0.99
88_K	197_Q	1.211	0.99
87_K	285_K	1.210	0.99
243_F	253_N	1.206	0.99
364_L	368_Y	1.193	0.99
412_E	424_A	1.188	0.99
520_R	561_I	1.188	0.99
331_N	335_E	1.183	0.99
354_K	387_S	1.178	0.99
180_Y	202_V	1.178	0.99
145_I	178_M	1.172	0.99
52_A	189_K	1.171	0.99
440_K	444_I	1.170	0.99
295_Q	299_E	1.168	0.99
250_S	253_N	1.161	0.98
129_F	153_V	1.157	0.98
349_E	377_N	1.155	0.98
505_N	511_F	1.153	0.98
46_N	165_S	1.152	0.98
80_S	283_L	1.150	0.98
52_A	186_I	1.148	0.98
101_D	107_I	1.143	0.98
145_I	182_F	1.139	0.98
204_I	258_I	1.139	0.98
236_K	297_E	1.135	0.98
59_L	65_L	1.134	0.98
64_K	117_D	1.133	0.98
58_H	118_L	1.132	0.98
76_Y	262_I	1.130	0.98
55_L	118_L	1.126	0.98
397_F	418_P	1.125	0.98
207_I	255_Q	1.119	0.98
52_A	185_A	1.119	0.98
364_L	374_L	1.117	0.98
85_Y	187_D	1.116	0.98
119_V	135_L	1.116	0.98
508_T	511_F	1.114	0.98
42_Y	48_I	1.113	0.98
48_I	185_A	1.112	0.98
386_L	427_R	1.105	0.98
487_A	543_I	1.101	0.98
112_I	140_T	1.101	0.98
233_L	281_F	1.100	0.98
129_F	151_E	1.100	0.98
52_A	56_I	1.099	0.98
273_E	299_E	1.099	0.98
204_I	254_T	1.098	0.98
342_K	438_N	1.098	0.98
30_L	215_N	1.098	0.98
262_I	282_L	1.093	0.98
43_S	48_I	1.090	0.98
517_E	556_T	1.087	0.98
464_K	548_A	1.086	0.98
232_P	236_K	1.085	0.98
77_T	174_T	1.084	0.98
135_L	142_I	1.083	0.98
446_I	449_D	1.082	0.98
327_V	331_N	1.082	0.98
40_I	169_S	1.077	0.98
238_F	258_I	1.076	0.98
492_E	539_V	1.076	0.98
34_V	223_N	1.073	0.97
135_L	140_T	1.071	0.97
500_H	504_K	1.071	0.97
110_D	114_D	1.057	0.97
292_K	296_S	1.055	0.97
118_L	141_E	1.054	0.97
47_N	165_S	1.051	0.97
105_H	131_E	1.051	0.97
399_K	414_V	1.048	0.97
238_F	243_F	1.047	0.97
39_V	220_Y	1.044	0.97
56_I	60_N	1.042	0.97
13_F	16_L	1.039	0.97
453_V	487_A	1.039	0.97
544_G	559_I	1.036	0.97
57_R	63_N	1.036	0.97
174_T	206_N	1.031	0.97
64_K	94_N	1.030	0.97
494_E	512_K	1.026	0.97
177_G	205_G	1.019	0.97
29_K	33_N	1.017	0.96
67_V	122_P	1.014	0.96
77_T	176_A	1.013	0.96
99_I	354_K	1.007	0.96
471_D	474_K	1.005	0.96
81_I	202_V	1.003	0.96
437_L	441_F	1.002	0.96
488_I	491_L	1.001	0.96
328_E	352_L	1.000	0.96
106_G	109_I	0.999	0.96
322_V	363_Q	0.995	0.96
333_I	368_Y	0.992	0.96
126_S	158_I	0.989	0.96
54_C	118_L	0.986	0.96
299_E	313_N	0.984	0.96
73_V	208_A	0.983	0.96
33_N	472_G	0.981	0.96
440_K	443_D	0.981	0.96
321_I	356_L	0.980	0.96
465_E	468_L	0.977	0.96
168_Y	181_K	0.977	0.96
241_Q	261_L	0.976	0.96
126_S	150_C	0.975	0.96
36_Q	224_E	0.975	0.96
436_V	439_E	0.971	0.95
492_E	512_K	0.971	0.95
130_E	133_E	0.970	0.95
430_L	434_N	0.968	0.95
347_Y	386_L	0.965	0.95
17_A	21_K	0.965	0.95
412_E	425_I	0.962	0.95
223_N	227_K	0.959	0.95
330_K	368_Y	0.958	0.95
244_S	247_G	0.957	0.95
401_F	404_E	0.956	0.95
58_H	141_E	0.953	0.95
483_E	545_K	0.946	0.95
313_N	317_K	0.945	0.95
436_V	440_K	0.945	0.95
540_I	564_L	0.943	0.95
388_G	423_F	0.938	0.94
373_L	390_I	0.937	0.94
55_L	186_I	0.937	0.94
373_L	402_K	0.936	0.94
460_K	513_H	0.935	0.94
124_A	128_Q	0.933	0.94
128_Q	131_E	0.932	0.94
210_S	479_Y	0.932	0.94
342_K	442_K	0.932	0.94
224_E	228_K	0.932	0.94
213_S	222_M	0.932	0.94
467_I	548_A	0.931	0.94
154_S	163_Q	0.931	0.94
23_R	454_D	0.929	0.94
405_L	440_K	0.929	0.94
509_V	518_Y	0.928	0.94
519_I	558_Q	0.927	0.94
395_K	418_P	0.925	0.94
390_I	423_F	0.922	0.94
236_K	239_K	0.920	0.94
14_D	461_R	0.919	0.94
68_Q	107_I	0.917	0.94
31_F	481_V	0.915	0.94
88_K	198_F	0.914	0.94
101_D	110_D	0.913	0.94
325_A	356_L	0.912	0.94
133_E	136_N	0.911	0.94
36_Q	39_V	0.908	0.93
230_K	247_G	0.907	0.93
45_L	48_I	0.904	0.93
294_G	298_T	0.902	0.93
36_Q	199_L	0.901	0.93
550_E	553_G	0.901	0.93
35_D	38_S	0.900	0.93
79_S	279_R	0.895	0.93
40_I	181_K	0.893	0.93
343_V	441_F	0.890	0.93
81_I	198_F	0.890	0.93
62_K	92_K	0.890	0.93
94_N	114_D	0.886	0.93
499_E	517_E	0.886	0.93
411_F	423_F	0.886	0.93
469_Q	472_G	0.883	0.93
467_I	546_A	0.881	0.92
83_I	93_A	0.880	0.92
109_I	138_R	0.878	0.92
121_I	145_I	0.877	0.92
108_F	135_L	0.872	0.92
135_L	138_R	0.872	0.92
338_L	341_N	0.872	0.92
13_F	17_A	0.871	0.92
177_G	211_A	0.867	0.92
505_N	508_T	0.867	0.92
229_I	254_T	0.866	0.92
85_Y	89_I	0.864	0.92
254_T	259_N	0.863	0.92
189_K	193_N	0.860	0.91
404_E	443_D	0.859	0.91
438_N	442_K	0.859	0.91
373_L	433_V	0.859	0.91
405_L	411_F	0.859	0.91
405_L	436_V	0.858	0.91
298_T	313_N	0.857	0.91
76_Y	271_S	0.857	0.91
36_Q	220_Y	0.856	0.91
396_G	445_N	0.856	0.91
253_N	257_F	0.855	0.91
82_I	183_C	0.854	0.91
410_L	432_L	0.851	0.91
18_T	22_N	0.851	0.91
71_S	103_K	0.851	0.91
331_N	334_E	0.849	0.91
284_S	296_S	0.847	0.91
401_F	440_K	0.846	0.91
273_E	314_L	0.846	0.91
199_L	202_V	0.843	0.91
41_H	48_I	0.843	0.91
19_I	455_F	0.839	0.90
404_E	444_I	0.839	0.90
431_I	435_K	0.836	0.90
69_V	95_I	0.835	0.90
220_Y	224_E	0.835	0.90
281_F	296_S	0.831	0.90
67_V	82_I	0.830	0.90
491_L	542_V	0.822	0.90
168_Y	217_E	0.818	0.89
272_E	280_A	0.817	0.89
80_S	279_R	0.815	0.89
76_Y	274_K	0.815	0.89
240_K	298_T	0.812	0.89
469_Q	473_Y	0.809	0.89
17_A	28_P	0.809	0.89
132_H	156_H	0.808	0.89
345_I	433_V	0.807	0.89
84_N	198_F	0.804	0.89
54_C	57_R	0.802	0.88
239_K	244_S	0.801	0.88
464_K	557_P	0.801	0.88
410_L	433_V	0.800	0.88
287_K	294_G	0.798	0.88
53_D	57_R	0.797	0.88
356_L	360_V	0.794	0.88
547_K	558_Q	0.791	0.88
325_A	360_V	0.791	0.88
434_N	438_N	0.790	0.88
493_I	540_I	0.788	0.88
41_H	44_K	0.788	0.88
126_S	175_G	0.787	0.87
492_E	510_K	0.785	0.87
94_N	116_V	0.784	0.87
25_I	28_P	0.783	0.87
160_V	163_Q	0.782	0.87
549_N	555_K	0.781	0.87
279_R	283_L	0.778	0.87
160_V	166_P	0.778	0.87
326_G	330_K	0.774	0.87
44_K	48_I	0.771	0.86
180_Y	221_F	0.770	0.86
39_V	180_Y	0.769	0.86
459_A	491_L	0.768	0.86
365_A	419_N	0.766	0.86
468_L	548_A	0.765	0.86
510_K	517_E	0.764	0.86
464_K	555_K	0.760	0.86
49_D	189_K	0.759	0.85
402_K	411_F	0.759	0.85
345_I	430_L	0.759	0.85
265_A	274_K	0.758	0.85
183_C	187_D	0.757	0.85
345_I	434_N	0.757	0.85
252_Q	257_F	0.756	0.85
39_V	221_F	0.756	0.85
170_N	215_N	0.755	0.85
206_N	222_M	0.753	0.85
493_I	531_L	0.752	0.85
200_D	228_K	0.751	0.85
545_K	560_E	0.750	0.85
365_A	372_V	0.749	0.85
81_I	85_Y	0.746	0.85
328_E	331_N	0.746	0.85
40_I	168_Y	0.746	0.85
204_I	234_L	0.745	0.84
332_R	346_V	0.745	0.84
490_D	541_N	0.741	0.84
40_I	44_K	0.739	0.84
354_K	378_D	0.739	0.84
236_K	294_G	0.739	0.84
467_I	471_D	0.735	0.84
175_G	178_M	0.735	0.84
179_A	182_F	0.734	0.84
240_K	297_E	0.733	0.83
385_I	424_A	0.732	0.83
204_I	229_I	0.730	0.83
57_R	189_K	0.730	0.83
79_S	95_I	0.730	0.83
227_K	230_K	0.728	0.83
317_K	320_R	0.727	0.83
51_A	118_L	0.727	0.83
172_T	212_D	0.726	0.83
341_N	370_K	0.726	0.83
162_N	171_K	0.725	0.83
517_E	558_Q	0.725	0.83
77_T	201_L	0.725	0.83
111_T	116_V	0.724	0.83
99_I	353_D	0.724	0.83
18_T	461_R	0.724	0.83
82_I	120_I	0.724	0.83
375_A	425_I	0.723	0.83
334_E	368_Y	0.723	0.83
325_A	352_L	0.722	0.83
250_S	474_K	0.716	0.82
516_I	559_I	0.715	0.82
471_D	548_A	0.713	0.82
201_L	231_H	0.713	0.82
159_V	182_F	0.713	0.82
445_N	450_I	0.712	0.82
462_L	557_P	0.710	0.81
509_V	561_I	0.710	0.81
232_P	287_K	0.710	0.81
64_K	116_V	0.710	0.81
107_I	111_T	0.709	0.81
411_F	433_V	0.709	0.81
455_F	486_I	0.708	0.81
369_K	395_K	0.707	0.81
329_I	364_L	0.707	0.81
55_L	65_L	0.706	0.81
170_N	217_E	0.706	0.81
71_S	98_R	0.705	0.81
54_C	117_D	0.704	0.81
108_F	134_A	0.703	0.81
423_F	437_L	0.702	0.81
293_R	297_E	0.700	0.81
39_V	202_V	0.698	0.80
80_S	201_L	0.698	0.80
399_K	403_K	0.698	0.80
281_F	297_E	0.698	0.80
95_I	362_N	0.698	0.80
357_T	390_I	0.696	0.80
319_K	323_D	0.696	0.80
67_V	93_A	0.692	0.80
126_S	154_S	0.690	0.80
235_K	239_K	0.689	0.80
145_I	179_A	0.688	0.79
27_D	30_L	0.686	0.79
377_N	430_L	0.682	0.79
112_I	115_D	0.681	0.79
240_K	294_G	0.678	0.78
206_N	218_T	0.678	0.78
349_E	427_R	0.675	0.78
43_S	188_E	0.675	0.78
20_L	473_Y	0.673	0.78
232_P	285_K	0.672	0.78
329_I	352_L	0.670	0.78
465_E	469_Q	0.670	0.78
237_L	297_E	0.669	0.77
315_K	318_Q	0.668	0.77
71_S	102_G	0.665	0.77
126_S	145_I	0.665	0.77
284_S	287_K	0.664	0.77
97_Y	269_G	0.664	0.77
87_K	283_L	0.664	0.77
456_E	488_I	0.664	0.77
353_D	359_L	0.664	0.77
457_I	462_L	0.663	0.77
519_I	560_E	0.661	0.77
120_I	143_I	0.658	0.76
464_K	467_I	0.656	0.76
163_Q	171_K	0.656	0.76
343_V	373_L	0.656	0.76
474_K	477_W	0.655	0.76
441_F	445_N	0.654	0.76
174_T	177_G	0.653	0.76
180_Y	184_Q	0.651	0.76
90_C	93_A	0.650	0.75
333_I	337_S	0.649	0.75
486_I	544_G	0.648	0.75
189_K	192_K	0.647	0.75
68_Q	124_A	0.647	0.75
273_E	296_S	0.647	0.75
512_K	515_D	0.645	0.75
395_K	449_D	0.644	0.75
85_Y	198_F	0.643	0.75
244_S	248_D	0.643	0.75
328_E	350_G	0.642	0.75
487_A	541_N	0.642	0.75
115_D	140_T	0.641	0.74
500_H	506_K	0.640	0.74
521_F	560_E	0.638	0.74
501_L	505_N	0.637	0.74
507_T	518_Y	0.637	0.74
212_D	479_Y	0.637	0.74
242_E	316_A	0.637	0.74
95_I	271_S	0.634	0.74
243_F	257_F	0.634	0.74
373_L	398_I	0.633	0.74
129_F	156_H	0.633	0.74
280_A	296_S	0.632	0.73
126_S	157_A	0.632	0.73
130_E	134_A	0.632	0.73
122_P	145_I	0.632	0.73
506_K	513_H	0.631	0.73
398_I	421_A	0.631	0.73
210_S	362_N	0.631	0.73
234_L	238_F	0.631	0.73
501_L	521_F	0.631	0.73
56_I	186_I	0.628	0.73
392_G	421_A	0.628	0.73
352_L	357_T	0.628	0.73
179_A	183_C	0.627	0.73
456_E	487_A	0.627	0.73
26_E	30_L	0.626	0.73
69_V	122_P	0.626	0.73
43_S	52_A	0.626	0.73
79_S	179_A	0.624	0.72
385_I	426_K	0.624	0.72
45_L	168_Y	0.623	0.72
98_R	102_G	0.623	0.72
154_S	157_A	0.621	0.72
466_F	470_L	0.616	0.72
56_I	59_L	0.616	0.72
236_K	293_R	0.616	0.72
40_I	170_N	0.614	0.71
427_R	430_L	0.614	0.71
322_V	356_L	0.612	0.71
101_D	106_G	0.612	0.71
253_N	259_N	0.612	0.71
158_I	161_N	0.611	0.71
116_V	140_T	0.610	0.71
172_T	211_A	0.610	0.71
84_N	87_K	0.609	0.71
232_P	235_K	0.608	0.71
322_V	352_L	0.608	0.71
499_E	508_T	0.607	0.70
121_I	175_G	0.607	0.70
45_L	166_P	0.607	0.70
196_E	224_E	0.606	0.70
112_I	117_D	0.606	0.70
459_A	488_I	0.606	0.70
150_C	160_V	0.606	0.70
108_F	111_T	0.605	0.70
126_S	160_V	0.605	0.70
333_I	338_L	0.603	0.70
274_K	279_R	0.602	0.70
194_E	197_Q	0.601	0.70
16_L	20_L	0.600	0.70
63_N	118_L	0.600	0.70
229_I	249_K	0.598	0.69
266_I	415_E	0.596	0.69
500_H	524_D	0.594	0.69
493_I	498_I	0.593	0.69
124_A	127_S	0.593	0.69
488_I	546_A	0.592	0.69
409_G	432_L	0.592	0.69
446_I	450_I	0.592	0.69
344_L	372_V	0.591	0.68
32_V	473_Y	0.591	0.68
133_E	153_V	0.591	0.68
314_L	317_K	0.590	0.68
44_K	168_Y	0.590	0.68
180_Y	196_E	0.589	0.68
441_F	444_I	0.589	0.68
230_K	238_F	0.588	0.68
369_K	450_I	0.588	0.68
269_G	273_E	0.587	0.68
177_G	180_Y	0.587	0.68
152_R	164_L	0.585	0.68
68_Q	111_T	0.584	0.67
271_S	274_K	0.583	0.67
65_L	89_I	0.583	0.67
57_R	141_E	0.582	0.67
233_L	297_E	0.581	0.67
110_D	113_P	0.581	0.67
46_N	171_K	0.581	0.67
346_V	372_V	0.581	0.67
334_E	367_E	0.581	0.67
121_I	142_I	0.580	0.67
500_H	528_F	0.578	0.67
411_F	425_I	0.578	0.67
196_E	228_K	0.577	0.67
329_I	346_V	0.577	0.67
18_T	455_F	0.577	0.67
350_G	377_N	0.576	0.66
122_P	179_A	0.573	0.66
85_Y	186_I	0.572	0.66
153_V	156_H	0.572	0.66
252_Q	483_E	0.571	0.66
502_G	505_N	0.571	0.66
280_A	284_S	0.571	0.66
295_Q	298_T	0.571	0.66
269_G	299_E	0.570	0.66
11_Y	17_A	0.570	0.66
457_I	546_A	0.569	0.65
201_L	282_L	0.567	0.65
325_A	348_I	0.566	0.65
80_S	200_D	0.565	0.65
16_L	466_F	0.565	0.65
345_I	375_A	0.565	0.65
337_S	340_A	0.564	0.65
73_V	124_A	0.564	0.65
78_S	174_T	0.564	0.65
356_L	359_L	0.562	0.65
122_P	175_G	0.561	0.64
362_N	366_E	0.561	0.64
403_K	414_V	0.560	0.64
505_N	522_K	0.560	0.64
208_A	254_T	0.560	0.64
66_F	114_D	0.560	0.64
86_I	89_I	0.559	0.64
229_I	238_F	0.558	0.64
45_L	163_Q	0.557	0.64
162_N	172_T	0.555	0.64
258_I	281_F	0.553	0.63
84_N	283_L	0.553	0.63
73_V	77_T	0.552	0.63
383_K	427_R	0.552	0.63
55_L	183_C	0.550	0.63
229_I	258_I	0.550	0.63
11_Y	29_K	0.550	0.63
269_G	314_L	0.550	0.63
176_A	180_Y	0.549	0.63
174_T	211_A	0.549	0.63
233_L	237_L	0.548	0.63
151_E	399_K	0.548	0.63
507_T	524_D	0.547	0.62
69_V	475_D	0.547	0.62
459_A	513_H	0.547	0.62
500_H	525_E	0.547	0.62
501_L	504_K	0.546	0.62
385_I	413_F	0.546	0.62
19_I	22_N	0.546	0.62
187_D	194_E	0.546	0.62
78_S	122_P	0.546	0.62
348_I	376_R	0.546	0.62
320_R	323_D	0.545	0.62
239_K	287_K	0.544	0.62
197_Q	228_K	0.543	0.62
498_I	509_V	0.543	0.62
143_I	182_F	0.543	0.62
529_N	532_T	0.543	0.62
402_K	414_V	0.543	0.62
322_V	362_N	0.542	0.62
107_I	386_L	0.542	0.62
109_I	137_K	0.542	0.62
112_I	134_A	0.541	0.62
364_L	551_Y	0.541	0.62
121_I	178_M	0.540	0.61
168_Y	184_Q	0.540	0.61
488_I	559_I	0.539	0.61
211_A	479_Y	0.538	0.61
393_Y	449_D	0.538	0.61
409_G	412_E	0.536	0.61
211_A	264_A	0.535	0.61
118_L	140_T	0.534	0.61
299_E	314_L	0.534	0.61
150_C	164_L	0.533	0.60
494_E	510_K	0.531	0.60
501_L	508_T	0.531	0.60
108_F	112_I	0.530	0.60
241_Q	312_G	0.529	0.60
34_V	220_Y	0.529	0.60
332_R	335_E	0.529	0.60
38_S	220_Y	0.528	0.60
254_T	258_I	0.528	0.60
413_F	424_A	0.528	0.60
40_I	184_Q	0.528	0.60
149_E	399_K	0.528	0.60
338_L	434_N	0.528	0.60
393_Y	450_I	0.527	0.60
183_C	198_F	0.527	0.60
375_A	411_F	0.526	0.59
188_E	192_K	0.526	0.59
132_H	158_I	0.525	0.59
80_S	84_N	0.524	0.59
506_K	517_E	0.524	0.59
463_R	546_A	0.523	0.59
200_D	225_G	0.523	0.59
112_I	135_L	0.522	0.59
411_F	429_N	0.522	0.59
261_L	297_E	0.522	0.59
518_Y	559_I	0.519	0.58
76_Y	265_A	0.519	0.58
103_K	266_I	0.519	0.58
109_I	112_I	0.519	0.58
184_Q	217_E	0.517	0.58
494_E	498_I	0.516	0.58
237_L	258_I	0.516	0.58
543_I	563_E	0.515	0.58
377_N	425_I	0.514	0.58
83_I	86_I	0.514	0.58
238_F	253_N	0.513	0.58
352_L	355_S	0.513	0.58
73_V	174_T	0.513	0.58
68_Q	101_D	0.511	0.57
261_L	352_L	0.511	0.57
33_N	38_S	0.510	0.57
548_A	557_P	0.510	0.57
243_F	247_G	0.509	0.57
489_T	539_V	0.509	0.57
78_S	175_G	0.509	0.57
517_E	521_F	0.508	0.57
236_K	240_K	0.508	0.57
346_V	352_L	0.508	0.57
108_F	140_T	0.507	0.57
181_K	187_D	0.507	0.57
524_D	528_F	0.507	0.57
488_I	513_H	0.507	0.57
494_E	497_Q	0.507	0.57
26_E	29_K	0.507	0.57
245_T	248_D	0.507	0.57
187_D	195_A	0.506	0.57
552_K	556_T	0.506	0.57
500_H	561_I	0.505	0.56
68_Q	168_Y	0.505	0.56
427_R	431_I	0.503	0.56
230_K	245_T	0.503	0.56
408_T	414_V	0.500	0.56
477_W	484_P	0.500	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zxrA	1	0.8247	100	0.322	Contact Map
4ls9A	2	0.5174	100	0.814	Contact Map
3devA	2	0.5208	100	0.828	Contact Map
4py9A	2	0.5417	100	0.836	Contact Map
1wpnA	2	0.2969	99.4	0.914	Contact Map
2hawA	2	0.5017	98.3	0.944	Contact Map
1k20A	2	0.4601	97.9	0.949	Contact Map
4rpaA	3	0.4965	97.9	0.95	Contact Map
2eb0A	2	0.4809	97.1	0.956	Contact Map
2qb7A	1	0.5573	96.3	0.961	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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