YORL - BACSU - GREMLIN Contacts

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YORL - Probable DNA polymerase YorL

UniProt:	O31902	Sequences: MIGCHCHTDRSNIRLLDSTNSVKELLKTAVKMEYKGLAITDHEVLSAHLDAIRTVREMKKKGDMPEDFKLILGNEAYLVDSLEEVRDNYKSGVTKFPHFLMLAMDPKGHEQLRILSSQAWENSFYTGTMERVPTVKKDVEELLSKDPGHIIATTACLGSEVNIHLLKIKAFEETGDSQSIKQHKLKIHEFITWCIEVFGKDKFFIELQPALSEEQIYCNKKLIDIANGYDLQMIVTTDAHYLRPEDRAIHQAFLNAKDGEREVDSFYEACFVQNVDEIHERMDYIDKEVIDQAIKNTMLIGEMIEDYTIEHEPIIPKMELPNFKLRHLFKPAYDQYEYIKKMSESADEQDRYLLKLIEDGFEEKLKTSELTREAFHKILNRINVELGELWEISQKLNQSMSSYYITVREIINIIWDDECGGDSLVGAARGSAAGYLVNYLLDNTQINPMQYDLPHWRHIHKSRPDLPDIDIDTEGSKRQKILKALRERFGDKRVLQIATFGTEGSKSALQTACRGLGIDNDISQYLSGMIPFERGSNWPLKHCFYGDKETGRKPIKEFIREVEQYPNLKETALKIEGLTNKRSSHAAGVIIFNDEYTKSNAMMKTPKGAYITQFNMGDSEAMGSVKFDLLTIEALDKIRVTLDQLIENNEIEWQGSLKETYNKYIHPDVIEYEDDKLWEMAGNGEIMDLFQFSTEVGHQSVVKVKPKNLLEAAVTNSLMRLMSDGEEQPVDTYVKYKNNLNKWYEEMTRYGLSEKEIRVMERHLKDIYGVADTQEVVMQMVMDKDIANFDIKESNYLRKSIAKKKEDVLKEVEELFFKKGKEIGTSDNLLNYVWNVQFKRQFGYSFSLLHTLAYSIIALQELNLNYRYNPLYWNTACLTVNSGGIDTEDTKDNKKTAATNYGKVASAIGNIRQRGIKIDLPDINKADFGFRTDINNNSILFGLKGMNGIGDDVIHHIVLNRPYSDFNDFIERMFKSGIIKKGQVIQLIKGGCFDSFGNRQEIMKAFISLISEPKSKLTLSNLKMLIENNIVPSEFAQEVRFFRFKDYISKKVYKTLKSPKDKLFLLDDVSASFYNQHFSEDSVVDMLNGQLVISEKAFKKEYDNKMSNIKSWITTEEPLKKLNDCLLIKEWEKYADGSLGKWEMDSLSYYYNDHELSGVNFAKYDIADFYKLPAEPVKGKPYQWRGKTLYEYETTRIIGTVLDRDKNKHAITLLTPTGVVTVKQWSGSFSHYNKQISRSIGGGKKEVIEKSWYTRGTLLMFTGFRRGNNFIPKVYKDSIYNHTVCRIDFVDNEGSMSLTTKRAEI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1305 (1058)
Sequences:	4448 (2673)
Seq/√Len:	82.2

ECOLI - DPO3A
BACSU - YORL DPO3A

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
761_E	765_K	6.365	1.00
477_K	480_K	6.112	1.00
646_I	664_Y	5.838	1.00
8_T	39_I	5.661	1.00
188_H	228_G	5.118	1.00
107_K	148_G	4.290	1.00
758_R	761_E	4.222	1.00
513_C	523_S	4.112	1.00
104_M	303_M	3.975	1.00
1124_D	1163_K	3.905	1.00
28_T	31_K	3.790	1.00
922_D	995_S	3.789	1.00
355_K	359_D	3.788	1.00
735_K	740_L	3.624	1.00
793_E	815_L	3.528	1.00
681_A	692_F	3.463	1.00
412_N	416_D	3.429	1.00
104_M	202_K	3.400	1.00
347_D	355_K	3.311	1.00
28_T	32_M	3.239	1.00
732_T	746_E	3.233	1.00
818_K	822_E	3.219	1.00
363_E	442_D	3.195	1.00
679_E	682_G	3.021	1.00
409_E	484_A	2.997	1.00
666_H	669_V	2.980	1.00
827_D	831_N	2.954	1.00
960_N	963_Y	2.944	1.00
358_E	379_L	2.942	1.00
806_E	810_K	2.914	1.00
137_K	193_W	2.903	1.00
814_E	818_K	2.893	1.00
347_D	351_R	2.844	1.00
29_A	37_L	2.804	1.00
432_A	469_I	2.786	1.00
169_K	186_K	2.771	1.00
735_K	746_E	2.762	1.00
296_N	299_L	2.705	1.00
389_L	437_V	2.684	1.00
365_L	378_I	2.683	1.00
354_L	383_N	2.621	1.00
638_I	864_L	2.598	1.00
541_K	573_L	2.590	1.00
366_K	369_E	2.589	1.00
161_V	203_F	2.531	1.00
639_R	643_D	2.528	1.00
789_F	812_V	2.516	1.00
821_K	827_D	2.511	1.00
53_R	621_A	2.508	1.00
234_I	300_I	2.487	1.00
675_D	679_E	2.473	1.00
676_K	679_E	2.441	1.00
1147_L	1165_D	2.407	1.00
26_L	55_V	2.381	1.00
101_M	152_A	2.358	1.00
262_E	515_G	2.356	1.00
813_E	831_N	2.354	1.00
682_G	707_K	2.343	1.00
559_I	570_E	2.336	1.00
462_S	792_K	2.334	1.00
762_R	785_D	2.319	1.00
1096_K	1144_M	2.315	1.00
681_A	686_I	2.301	1.00
350_D	396_L	2.300	1.00
969_F	993_F	2.299	1.00
354_L	358_E	2.292	1.00
246_D	574_K	2.264	1.00
348_E	351_R	2.262	1.00
379_L	383_N	2.249	1.00
28_T	243_R	2.239	1.00
679_E	683_N	2.223	1.00
144_S	193_W	2.217	1.00
397_N	461_K	2.206	1.00
354_L	396_L	2.193	1.00
244_P	273_Q	2.188	1.00
372_R	380_N	2.184	1.00
917_K	938_S	2.175	1.00
677_L	867_R	2.171	1.00
703_K	731_D	2.169	1.00
692_F	712_A	2.158	1.00
638_I	667_P	2.140	1.00
153_T	234_I	2.126	1.00
919_D	940_L	2.125	1.00
69_K	305_E	2.122	1.00
676_K	867_R	2.117	1.00
186_K	189_E	2.117	1.00
27_K	61_K	2.114	1.00
685_E	914_R	2.113	1.00
835_N	839_K	2.105	1.00
387_G	397_N	2.087	1.00
725_G	730_V	2.069	1.00
445_Q	668_D	2.051	1.00
594_D	598_K	2.042	1.00
383_N	387_G	2.021	1.00
283_D	295_K	2.015	1.00
358_E	383_N	2.000	1.00
76_A	101_M	1.993	1.00
9_D	21_S	1.992	1.00
1051_K	1054_K	1.982	1.00
46_S	603_M	1.980	1.00
998_N	1049_S	1.978	1.00
413_I	481_I	1.969	1.00
817_F	831_N	1.960	1.00
831_N	835_N	1.959	1.00
193_W	197_V	1.953	1.00
483_K	487_E	1.941	1.00
205_I	226_A	1.941	1.00
759_V	825_T	1.941	1.00
1003_M	1050_K	1.939	1.00
763_H	785_D	1.930	1.00
283_D	294_I	1.926	1.00
508_A	575_I	1.923	1.00
350_D	401_S	1.922	1.00
788_N	823_I	1.914	1.00
955_H	959_L	1.913	1.00
353_L	386_L	1.911	1.00
202_K	303_M	1.909	1.00
106_P	110_E	1.903	1.00
223_I	233_M	1.897	1.00
498_A	582_R	1.894	1.00
813_E	835_N	1.890	1.00
191_I	231_L	1.889	1.00
248_A	567_N	1.883	1.00
195_I	231_L	1.875	1.00
37_L	276_D	1.874	1.00
759_V	823_I	1.866	1.00
263_V	517_G	1.865	1.00
951_D	955_H	1.864	1.00
679_E	707_K	1.860	1.00
154_T	203_F	1.855	1.00
1091_L	1147_L	1.851	1.00
260_E	264_D	1.839	1.00
784_K	791_I	1.836	1.00
699_Q	703_K	1.831	1.00
54_T	61_K	1.829	1.00
557_E	561_E	1.827	1.00
726_E	730_V	1.823	1.00
750_Y	761_E	1.818	1.00
725_G	728_Q	1.818	1.00
1113_I	1126_L	1.817	1.00
105_D	149_H	1.815	1.00
5_H	75_E	1.804	1.00
413_I	417_D	1.802	1.00
813_E	839_K	1.790	1.00
661_Y	868_Y	1.785	1.00
408_R	412_N	1.783	1.00
118_Q	145_K	1.779	1.00
359_D	363_E	1.775	1.00
20_N	242_L	1.770	1.00
288_E	291_D	1.767	1.00
224_D	228_G	1.758	1.00
29_A	276_D	1.757	1.00
1068_D	1072_S	1.746	1.00
485_L	629_L	1.745	1.00
960_N	972_R	1.741	1.00
636_D	640_V	1.739	1.00
760_M	780_M	1.735	1.00
910_N	914_R	1.733	1.00
965_D	1041_F	1.732	1.00
74_N	116_S	1.732	1.00
713_A	852_L	1.731	1.00
357_I	382_I	1.729	1.00
509_L	530_I	1.720	1.00
1104_N	1110_K	1.719	1.00
452_D	779_Q	1.714	1.00
423_S	480_K	1.712	1.00
682_G	705_K	1.710	1.00
191_I	229_Y	1.709	1.00
817_F	821_K	1.709	1.00
23_K	54_T	1.709	1.00
273_Q	277_E	1.708	1.00
38_A	102_L	1.706	1.00
1201_V	1210_A	1.704	1.00
727_E	730_V	1.703	1.00
510_Q	524_Q	1.701	1.00
365_L	436_L	1.699	1.00
1148_S	1161_F	1.697	1.00
692_F	716_N	1.695	1.00
309_I	312_E	1.693	1.00
398_Q	464_P	1.692	1.00
298_M	302_E	1.688	1.00
1000_Q	1004_K	1.688	1.00
728_Q	731_D	1.681	1.00
206_E	236_T	1.666	1.00
364_K	445_Q	1.660	1.00
9_D	578_L	1.648	1.00
633_E	880_V	1.644	1.00
106_P	306_D	1.639	1.00
40_T	102_L	1.634	1.00
239_A	276_D	1.632	1.00
204_F	299_L	1.623	1.00
192_T	229_Y	1.623	1.00
988_I	1002_I	1.619	1.00
786_I	833_V	1.616	1.00
988_I	1006_F	1.616	1.00
188_H	192_T	1.611	1.00
510_Q	527_S	1.610	1.00
112_L	150_I	1.606	1.00
646_I	662_N	1.606	1.00
556_K	560_R	1.604	1.00
356_L	359_D	1.600	1.00
771_A	780_M	1.590	1.00
144_S	197_V	1.588	1.00
1149_Y	1164_Y	1.585	1.00
279_H	283_D	1.578	1.00
559_I	569_K	1.577	1.00
1124_D	1146_S	1.575	1.00
796_Y	799_K	1.568	1.00
524_Q	528_G	1.566	1.00
1049_S	1055_T	1.563	1.00
371_T	378_I	1.562	1.00
1005_A	1045_K	1.562	1.00
739_N	746_E	1.559	1.00
727_E	731_D	1.558	1.00
987_L	992_C	1.543	1.00
233_M	293_A	1.541	1.00
874_N	911_I	1.533	0.99
700_S	715_T	1.533	0.99
237_T	277_E	1.530	0.99
806_E	843_G	1.524	0.99
103_A	306_D	1.523	0.99
349_Q	402_S	1.522	0.99
476_S	640_V	1.521	0.99
968_D	972_R	1.520	0.99
223_I	290_I	1.513	0.99
1146_S	1163_K	1.503	0.99
667_P	670_I	1.502	0.99
736_Y	746_E	1.500	0.99
536_S	542_H	1.497	0.99
725_G	851_T	1.495	0.99
209_P	216_I	1.493	0.99
677_L	866_Y	1.488	0.99
32_M	278_I	1.486	0.99
35_K	298_M	1.485	0.99
100_L	155_A	1.482	0.99
118_Q	122_N	1.481	0.99
716_N	855_S	1.478	0.99
874_N	914_R	1.476	0.99
566_P	570_E	1.473	0.99
361_F	440_L	1.472	0.99
409_E	488_R	1.469	0.99
252_A	571_T	1.468	0.99
750_Y	765_K	1.464	0.99
541_K	545_Y	1.463	0.99
812_V	815_L	1.462	0.99
21_S	24_E	1.461	0.99
417_D	420_G	1.461	0.99
709_L	856_I	1.456	0.99
232_Q	299_L	1.455	0.99
36_G	301_G	1.448	0.99
829_L	832_Y	1.447	0.99
360_G	440_L	1.444	0.99
50_D	618_D	1.437	0.99
423_S	477_K	1.432	0.99
396_L	401_S	1.429	0.99
661_Y	872_Y	1.428	0.99
808_V	812_V	1.428	0.99
685_E	913_Q	1.428	0.99
725_G	731_D	1.420	0.99
160_E	190_F	1.420	0.99
42_H	98_H	1.416	0.99
320_L	323_F	1.410	0.99
244_P	272_V	1.410	0.99
144_S	196_E	1.406	0.99
559_I	566_P	1.405	0.99
195_I	201_D	1.405	0.99
261_R	517_G	1.395	0.99
726_E	731_D	1.384	0.99
781_V	797_L	1.382	0.99
378_I	449_M	1.380	0.99
262_E	516_L	1.378	0.99
358_E	361_F	1.375	0.99
226_A	231_L	1.374	0.99
688_D	877_C	1.373	0.99
704_V	734_V	1.371	0.99
736_Y	739_N	1.368	0.99
98_H	156_C	1.363	0.99
117_S	602_M	1.360	0.99
165_L	225_I	1.355	0.99
617_G	805_K	1.353	0.99
356_L	408_R	1.350	0.99
30_V	61_K	1.350	0.99
411_I	471_I	1.347	0.99
736_Y	748_T	1.340	0.99
687_M	698_H	1.337	0.99
76_A	135_V	1.336	0.99
188_H	229_Y	1.336	0.99
164_H	169_K	1.333	0.99
287_K	291_D	1.331	0.99
382_I	440_L	1.330	0.99
820_G	825_T	1.327	0.99
277_E	285_I	1.325	0.99
878_L	904_V	1.324	0.99
83_E	122_N	1.321	0.98
672_Y	856_I	1.320	0.98
725_G	729_P	1.318	0.98
1098_F	1114_T	1.315	0.98
518_I	568_L	1.315	0.98
989_K	1058_S	1.311	0.98
925_K	935_N	1.308	0.98
634_A	873_W	1.303	0.98
45_L	109_H	1.302	0.98
204_F	303_M	1.302	0.98
114_I	598_K	1.301	0.98
522_I	564_Q	1.301	0.98
676_K	866_Y	1.300	0.98
497_I	588_G	1.298	0.98
707_K	737_K	1.295	0.98
680_M	866_Y	1.291	0.98
726_E	851_T	1.289	0.98
209_P	288_E	1.288	0.98
48_H	72_L	1.288	0.98
533_E	536_S	1.288	0.98
382_I	436_L	1.282	0.98
788_N	819_K	1.279	0.98
717_S	851_T	1.278	0.98
558_F	562_V	1.274	0.98
154_T	205_I	1.269	0.98
252_A	512_A	1.269	0.98
919_D	938_S	1.268	0.98
54_T	60_K	1.267	0.98
970_I	1009_L	1.265	0.98
452_D	766_D	1.264	0.98
299_L	303_M	1.262	0.98
709_L	713_A	1.259	0.98
165_L	221_K	1.257	0.98
641_T	876_A	1.257	0.98
513_C	568_L	1.252	0.98
153_T	206_E	1.252	0.98
1104_N	1128_I	1.251	0.98
946_M	990_G	1.248	0.98
23_K	60_K	1.248	0.98
646_I	665_I	1.247	0.98
1078_F	1093_I	1.245	0.98
686_I	692_F	1.244	0.98
371_T	377_K	1.243	0.98
251_Q	262_E	1.242	0.98
32_M	276_D	1.239	0.98
299_L	302_E	1.239	0.98
766_D	848_L	1.227	0.98
645_L	864_L	1.226	0.98
662_N	665_I	1.224	0.97
520_N	524_Q	1.219	0.97
927_D	931_R	1.218	0.97
1110_K	1127_L	1.215	0.97
26_L	54_T	1.214	0.97
667_P	860_Q	1.210	0.97
361_F	382_I	1.210	0.97
226_A	229_Y	1.209	0.97
671_E	859_L	1.209	0.97
925_K	962_P	1.209	0.97
104_M	108_G	1.207	0.97
107_K	149_H	1.206	0.97
76_A	116_S	1.202	0.97
37_L	55_V	1.200	0.97
808_V	811_E	1.198	0.97
275_V	281_R	1.197	0.97
1072_S	1118_P	1.197	0.97
633_E	881_N	1.197	0.97
1096_K	1113_I	1.196	0.97
320_L	351_R	1.194	0.97
25_L	239_A	1.194	0.97
553_K	556_K	1.192	0.97
716_N	851_T	1.191	0.97
51_A	70_L	1.190	0.97
969_F	984_V	1.186	0.97
195_I	230_D	1.186	0.97
26_L	61_K	1.184	0.97
191_I	225_I	1.182	0.97
205_I	231_L	1.181	0.97
1092_V	1115_T	1.178	0.97
44_V	120_W	1.173	0.97
207_L	290_I	1.173	0.97
511_T	580_N	1.172	0.97
446_I	852_L	1.172	0.97
378_I	436_L	1.171	0.97
957_I	969_F	1.171	0.97
45_L	113_R	1.171	0.97
52_I	310_E	1.171	0.97
353_L	441_L	1.171	0.97
17_D	42_H	1.165	0.97
417_D	487_E	1.165	0.97
789_F	815_L	1.163	0.97
554_P	557_E	1.159	0.97
160_E	194_C	1.152	0.96
185_L	189_E	1.152	0.96
384_V	387_G	1.150	0.96
479_Q	483_K	1.149	0.96
424_L	474_E	1.149	0.96
72_L	109_H	1.149	0.96
524_Q	527_S	1.148	0.96
245_E	574_K	1.148	0.96
42_H	156_C	1.147	0.96
791_I	799_K	1.145	0.96
826_S	829_L	1.145	0.96
499_T	586_A	1.143	0.96
103_A	150_I	1.141	0.96
251_Q	267_Y	1.140	0.96
949_I	983_Q	1.138	0.96
215_Q	219_N	1.137	0.96
83_E	141_E	1.136	0.96
928_F	955_H	1.135	0.96
1133_K	1165_D	1.134	0.96
701_V	715_T	1.133	0.96
71_I	102_L	1.132	0.96
59_K	307_Y	1.131	0.96
674_D	867_R	1.130	0.96
195_I	199_G	1.130	0.96
615_N	618_D	1.129	0.96
1000_Q	1047_Y	1.123	0.96
447_N	450_Q	1.122	0.96
730_V	851_T	1.120	0.96
77_Y	98_H	1.119	0.96
696_V	719_M	1.118	0.96
1056_L	1067_D	1.118	0.96
641_T	864_L	1.116	0.96
810_K	839_K	1.116	0.96
43_E	77_Y	1.116	0.96
199_G	202_K	1.113	0.96
34_Y	279_H	1.112	0.96
555_I	569_K	1.111	0.96
962_P	972_R	1.109	0.96
925_K	940_L	1.107	0.95
7_H	17_D	1.104	0.95
953_V	978_I	1.103	0.95
967_N	1042_F	1.102	0.95
207_L	293_A	1.100	0.95
1108_N	1129_K	1.100	0.95
544_F	569_K	1.099	0.95
726_E	729_P	1.097	0.95
1113_I	1124_D	1.097	0.95
759_V	786_I	1.097	0.95
516_L	571_T	1.095	0.95
357_I	436_L	1.092	0.95
352_Y	356_L	1.092	0.95
492_K	595_E	1.092	0.95
104_M	204_F	1.092	0.95
361_F	370_L	1.091	0.95
118_Q	146_D	1.091	0.95
17_D	156_C	1.091	0.95
960_N	973_M	1.089	0.95
727_E	851_T	1.088	0.95
569_K	573_L	1.088	0.95
411_I	425_V	1.087	0.95
321_P	352_Y	1.085	0.95
498_A	603_M	1.081	0.95
23_K	61_K	1.081	0.95
921_P	946_M	1.080	0.95
716_N	858_A	1.080	0.95
20_N	25_L	1.079	0.95
542_H	545_Y	1.077	0.95
221_K	224_D	1.075	0.95
21_S	578_L	1.074	0.95
692_F	855_S	1.074	0.95
204_F	296_N	1.074	0.95
350_D	354_L	1.074	0.95
432_A	438_N	1.071	0.95
347_D	352_Y	1.069	0.95
751_G	832_Y	1.069	0.95
874_N	907_A	1.067	0.94
168_I	217_Y	1.066	0.94
991_G	1067_D	1.066	0.94
194_C	203_F	1.066	0.94
152_A	198_F	1.065	0.94
137_K	194_C	1.064	0.94
685_E	910_N	1.063	0.94
998_N	1001_E	1.062	0.94
5_H	206_E	1.061	0.94
136_K	142_L	1.060	0.94
121_E	610_Y	1.059	0.94
681_A	716_N	1.058	0.94
188_H	225_I	1.058	0.94
484_A	488_R	1.057	0.94
1137_G	1168_D	1.057	0.94
786_I	825_T	1.056	0.94
1130_E	1134_Y	1.054	0.94
154_T	159_S	1.054	0.94
226_A	232_Q	1.051	0.94
354_L	386_L	1.051	0.94
779_Q	785_D	1.050	0.94
923_I	969_F	1.050	0.94
115_L	150_I	1.049	0.94
921_P	943_L	1.047	0.94
164_H	190_F	1.046	0.94
1130_E	1163_K	1.045	0.94
118_Q	142_L	1.044	0.94
227_N	292_Q	1.043	0.94
777_V	801_I	1.042	0.94
728_Q	851_T	1.042	0.94
32_M	279_H	1.041	0.94
199_G	231_L	1.041	0.94
410_I	485_L	1.039	0.94
1094_S	1124_D	1.039	0.94
235_V	293_A	1.038	0.94
105_D	108_G	1.038	0.94
475_G	634_A	1.037	0.94
790_D	793_E	1.035	0.94
1198_I	1202_L	1.035	0.94
954_I	957_I	1.034	0.93
1099_K	1113_I	1.034	0.93
306_D	309_I	1.033	0.93
151_I	204_F	1.032	0.93
687_M	907_A	1.032	0.93
361_F	378_I	1.030	0.93
1075_N	1118_P	1.028	0.93
909_G	913_Q	1.027	0.93
417_D	480_K	1.027	0.93
759_V	785_D	1.027	0.93
956_H	960_N	1.027	0.93
364_K	442_D	1.024	0.93
278_I	281_R	1.023	0.93
539_P	542_H	1.021	0.93
796_Y	812_V	1.021	0.93
307_Y	310_E	1.020	0.93
670_I	860_Q	1.020	0.93
114_I	597_T	1.019	0.93
52_I	308_T	1.017	0.93
638_I	642_L	1.016	0.93
151_I	303_M	1.016	0.93
164_H	186_K	1.016	0.93
22_V	54_T	1.016	0.93
638_I	860_Q	1.015	0.93
320_L	347_D	1.015	0.93
642_L	665_I	1.014	0.93
1153_D	1156_L	1.011	0.93
874_N	939_I	1.011	0.93
1181_P	1213_L	1.008	0.93
101_M	150_I	1.008	0.93
17_D	98_H	1.007	0.93
384_V	456_W	1.005	0.92
928_F	944_K	1.002	0.92
786_I	820_G	1.002	0.92
505_S	576_E	1.000	0.92
352_Y	408_R	0.999	0.92
930_F	941_F	0.998	0.92
739_N	747_M	0.997	0.92
710_L	766_D	0.997	0.92
46_S	120_W	0.996	0.92
6_C	25_L	0.995	0.92
1195_T	1198_I	0.994	0.92
412_N	442_D	0.991	0.92
1101_E	1109_I	0.990	0.92
163_I	166_L	0.990	0.92
732_T	770_V	0.989	0.92
1110_K	1125_C	0.987	0.92
137_K	160_E	0.987	0.92
817_F	827_D	0.987	0.92
1071_A	1078_F	0.987	0.92
1102_Y	1112_W	0.986	0.92
147_P	197_V	0.985	0.92
454_P	849_L	0.984	0.92
828_N	832_Y	0.984	0.92
1143_E	1169_F	0.982	0.92
24_E	27_K	0.981	0.92
7_H	75_E	0.979	0.91
121_E	604_K	0.979	0.91
192_T	196_E	0.978	0.91
105_D	148_G	0.978	0.91
678_W	859_L	0.977	0.91
156_C	240_H	0.976	0.91
1168_D	1171_K	0.976	0.91
1111_S	1131_W	0.976	0.91
923_I	993_F	0.975	0.91
244_P	275_V	0.974	0.91
474_E	636_D	0.969	0.91
600_N	612_T	0.968	0.91
1183_Q	1213_L	0.967	0.91
763_H	780_M	0.966	0.91
793_E	819_K	0.966	0.91
910_N	913_Q	0.962	0.91
518_I	522_I	0.959	0.91
191_I	203_F	0.959	0.91
553_K	557_E	0.956	0.90
110_E	598_K	0.956	0.90
98_H	240_H	0.955	0.90
201_D	232_Q	0.955	0.90
476_S	636_D	0.954	0.90
365_L	447_N	0.953	0.90
879_T	929_G	0.951	0.90
75_E	98_H	0.950	0.90
1001_E	1045_K	0.949	0.90
680_M	683_N	0.949	0.90
757_I	829_L	0.949	0.90
186_K	190_F	0.947	0.90
486_R	491_D	0.946	0.90
495_L	612_T	0.946	0.90
1153_D	1158_G	0.945	0.90
271_F	274_N	0.945	0.90
967_N	1009_L	0.943	0.90
24_E	246_D	0.942	0.90
953_V	983_Q	0.942	0.90
1052_V	1068_D	0.941	0.90
205_I	222_L	0.941	0.90
348_E	396_L	0.941	0.90
508_A	572_A	0.940	0.90
646_I	659_E	0.939	0.90
100_L	152_A	0.938	0.90
675_D	682_G	0.938	0.90
1104_N	1108_N	0.936	0.90
352_Y	355_K	0.935	0.89
646_I	663_K	0.935	0.89
590_I	612_T	0.934	0.89
665_I	863_N	0.934	0.89
544_F	559_I	0.934	0.89
1115_T	1146_S	0.932	0.89
420_G	639_R	0.932	0.89
361_F	436_L	0.932	0.89
705_K	738_N	0.931	0.89
1050_K	1058_S	0.930	0.89
818_K	821_K	0.929	0.89
1000_Q	1050_K	0.928	0.89
222_L	233_M	0.928	0.89
801_I	809_L	0.927	0.89
805_K	808_V	0.925	0.89
372_R	379_L	0.925	0.89
36_G	69_K	0.924	0.89
964_S	968_D	0.924	0.89
1054_K	1058_S	0.923	0.89
830_L	834_W	0.922	0.89
990_G	1062_K	0.921	0.89
5_H	236_T	0.919	0.89
930_F	945_G	0.918	0.89
700_S	734_V	0.914	0.88
692_F	858_A	0.912	0.88
872_Y	932_T	0.912	0.88
120_W	603_M	0.911	0.88
420_G	423_S	0.909	0.88
809_L	839_K	0.907	0.88
81_S	93_V	0.905	0.88
1144_M	1166_I	0.904	0.88
218_C	222_L	0.904	0.88
313_P	400_M	0.903	0.88
208_Q	236_T	0.903	0.88
526_L	565_Y	0.900	0.88
1152_N	1155_E	0.898	0.88
1092_V	1161_F	0.897	0.87
929_G	944_K	0.897	0.87
687_M	910_N	0.897	0.87
547_D	554_P	0.896	0.87
42_H	77_Y	0.895	0.87
779_Q	784_K	0.895	0.87
357_I	440_L	0.894	0.87
19_T	578_L	0.892	0.87
357_I	361_F	0.891	0.87
792_K	799_K	0.888	0.87
1026_I	1029_N	0.886	0.87
522_I	562_V	0.885	0.87
27_K	31_K	0.885	0.87
868_Y	872_Y	0.885	0.87
30_V	62_G	0.883	0.87
6_C	239_A	0.883	0.87
237_T	282_M	0.883	0.87
195_I	229_Y	0.882	0.87
284_Y	287_K	0.881	0.87
111_Q	149_H	0.880	0.86
108_G	111_Q	0.880	0.86
646_I	661_Y	0.879	0.86
358_E	362_E	0.877	0.86
997_G	1002_I	0.877	0.86
784_K	794_S	0.876	0.86
232_Q	303_M	0.875	0.86
97_P	160_E	0.875	0.86
252_A	515_G	0.875	0.86
523_S	568_L	0.874	0.86
300_I	304_I	0.874	0.86
102_L	153_T	0.874	0.86
525_Y	558_F	0.872	0.86
415_W	445_Q	0.871	0.86
434_G	849_L	0.871	0.86
1108_N	1132_E	0.870	0.86
1126_L	1163_K	0.870	0.86
911_I	918_I	0.869	0.86
27_K	54_T	0.869	0.86
699_Q	702_V	0.869	0.86
152_A	203_F	0.869	0.86
45_L	150_I	0.867	0.86
956_H	974_F	0.866	0.86
508_A	540_L	0.866	0.86
55_V	62_G	0.866	0.86
788_N	822_E	0.866	0.86
195_I	202_K	0.865	0.85
442_D	445_Q	0.865	0.85
984_V	1006_F	0.865	0.85
877_C	907_A	0.864	0.85
446_I	856_I	0.864	0.85
684_G	719_M	0.863	0.85
671_E	867_R	0.863	0.85
1122_L	1161_F	0.863	0.85
1200_T	1204_R	0.861	0.85
251_Q	268_E	0.861	0.85
281_R	284_Y	0.858	0.85
240_H	250_H	0.857	0.85
263_V	564_Q	0.855	0.85
645_L	872_Y	0.854	0.85
318_M	323_F	0.854	0.85
533_E	542_H	0.853	0.85
157_L	218_C	0.852	0.85
402_S	625_V	0.852	0.85
881_N	904_V	0.852	0.85
924_N	963_Y	0.851	0.85
114_I	595_E	0.850	0.84
420_G	643_D	0.850	0.84
275_V	278_I	0.849	0.84
949_I	990_G	0.849	0.84
17_D	240_H	0.848	0.84
36_G	68_F	0.847	0.84
37_L	239_A	0.845	0.84
497_I	586_A	0.845	0.84
297_T	301_G	0.844	0.84
715_T	858_A	0.844	0.84
981_K	1007_I	0.843	0.84
43_E	119_A	0.843	0.84
261_R	515_G	0.843	0.84
674_D	677_L	0.842	0.84
414_I	473_T	0.842	0.84
122_N	142_L	0.841	0.84
813_E	817_F	0.840	0.84
791_I	796_Y	0.839	0.84
1108_N	1128_I	0.838	0.84
692_F	701_V	0.837	0.84
7_H	240_H	0.836	0.83
506_K	513_C	0.834	0.83
117_S	121_E	0.834	0.83
700_S	703_K	0.834	0.83
729_P	851_T	0.833	0.83
417_D	481_I	0.833	0.83
778_M	849_L	0.831	0.83
505_S	534_R	0.831	0.83
700_S	727_E	0.831	0.83
1126_L	1166_I	0.830	0.83
264_D	267_Y	0.830	0.83
730_V	772_D	0.830	0.83
981_K	1010_I	0.829	0.83
1104_N	1125_C	0.829	0.83
678_W	708_N	0.829	0.83
762_R	765_K	0.828	0.83
749_R	832_Y	0.828	0.83
35_K	302_E	0.827	0.83
254_L	258_D	0.827	0.83
501_G	507_S	0.827	0.83
512_A	575_I	0.827	0.83
592_F	595_E	0.826	0.83
681_A	689_L	0.825	0.83
1196_R	1199_G	0.825	0.83
45_L	72_L	0.824	0.83
241_Y	270_C	0.824	0.83
24_E	243_R	0.824	0.83
661_Y	664_Y	0.824	0.83
526_L	558_F	0.823	0.83
79_V	136_K	0.822	0.82
450_Q	672_Y	0.821	0.82
1137_G	1144_M	0.820	0.82
714_V	733_Y	0.820	0.82
279_H	294_I	0.820	0.82
543_C	547_D	0.820	0.82
13_I	50_D	0.819	0.82
353_L	437_V	0.819	0.82
156_C	162_N	0.819	0.82
124_F	132_V	0.819	0.82
771_A	838_F	0.818	0.82
680_M	689_L	0.817	0.82
645_L	868_Y	0.816	0.82
292_Q	296_N	0.816	0.82
30_V	68_F	0.815	0.82
372_R	377_K	0.814	0.82
680_M	686_I	0.814	0.82
705_K	740_L	0.814	0.82
69_K	302_E	0.814	0.82
1052_V	1055_T	0.813	0.82
318_M	408_R	0.812	0.82
255_N	515_G	0.811	0.82
417_D	477_K	0.811	0.82
380_N	384_V	0.811	0.82
1139_L	1142_W	0.810	0.82
949_I	954_I	0.809	0.81
642_L	645_L	0.809	0.81
233_M	290_I	0.807	0.81
115_L	142_L	0.806	0.81
735_K	739_N	0.806	0.81
250_H	254_L	0.805	0.81
956_H	959_L	0.805	0.81
935_N	938_S	0.805	0.81
107_K	110_E	0.804	0.81
413_I	416_D	0.804	0.81
605_T	611_I	0.802	0.81
359_D	362_E	0.802	0.81
410_I	471_I	0.800	0.81
411_I	415_W	0.799	0.81
1111_S	1138_S	0.796	0.80
543_C	555_I	0.795	0.80
52_I	72_L	0.793	0.80
710_L	848_L	0.792	0.80
100_L	153_T	0.792	0.80
1094_S	1115_T	0.791	0.80
820_G	823_I	0.791	0.80
192_T	195_I	0.791	0.80
50_D	615_N	0.790	0.80
989_K	1061_D	0.790	0.80
317_K	593_N	0.789	0.80
757_I	825_T	0.786	0.80
253_F	578_L	0.786	0.80
1125_C	1151_Y	0.784	0.79
59_K	310_E	0.782	0.79
298_M	301_G	0.782	0.79
1126_L	1130_E	0.782	0.79
726_E	843_G	0.781	0.79
398_Q	466_L	0.781	0.79
26_L	30_V	0.780	0.79
75_E	240_H	0.779	0.79
644_Q	872_Y	0.778	0.79
1197_I	1212_T	0.776	0.79
1112_W	1162_A	0.776	0.79
810_K	814_E	0.775	0.79
714_V	768_Y	0.774	0.79
1128_I	1131_W	0.774	0.79
82_L	136_K	0.774	0.79
78_L	135_V	0.773	0.78
712_A	716_N	0.772	0.78
799_K	853_A	0.770	0.78
309_I	314_I	0.769	0.78
807_D	810_K	0.769	0.78
984_V	1010_I	0.768	0.78
99_F	152_A	0.768	0.78
377_K	380_N	0.768	0.78
152_A	197_V	0.768	0.78
78_L	99_F	0.767	0.78
772_D	843_G	0.767	0.78
49_L	306_D	0.767	0.78
269_A	274_N	0.767	0.78
875_T	879_T	0.766	0.78
320_L	348_E	0.766	0.78
840_R	843_G	0.765	0.78
425_V	473_T	0.765	0.78
32_M	280_E	0.765	0.78
41_D	47_A	0.763	0.78
205_I	220_K	0.763	0.78
953_V	975_K	0.762	0.77
695_E	699_Q	0.761	0.77
7_H	14_R	0.761	0.77
989_K	1003_M	0.760	0.77
111_Q	146_D	0.760	0.77
518_I	564_Q	0.760	0.77
232_Q	296_N	0.760	0.77
39_I	72_L	0.760	0.77
42_H	240_H	0.759	0.77
1163_K	1166_I	0.759	0.77
377_K	449_M	0.758	0.77
1113_I	1138_S	0.758	0.77
301_G	304_I	0.757	0.77
733_Y	748_T	0.757	0.77
529_M	558_F	0.756	0.77
380_N	383_N	0.756	0.77
356_L	412_N	0.755	0.77
49_L	308_T	0.754	0.77
801_I	838_F	0.754	0.77
223_I	227_N	0.754	0.77
638_I	641_T	0.752	0.76
126_T	132_V	0.751	0.76
155_A	206_E	0.750	0.76
716_N	772_D	0.750	0.76
37_L	68_F	0.750	0.76
169_K	185_L	0.750	0.76
235_V	294_I	0.750	0.76
522_I	565_Y	0.750	0.76
952_D	955_H	0.749	0.76
660_T	872_Y	0.749	0.76
544_F	556_K	0.749	0.76
834_W	839_K	0.748	0.76
587_A	616_M	0.747	0.76
1001_E	1005_A	0.747	0.76
29_A	55_V	0.747	0.76
71_I	939_I	0.747	0.76
189_E	193_W	0.745	0.76
151_I	300_I	0.744	0.76
398_Q	461_K	0.743	0.76
644_Q	932_T	0.743	0.76
414_I	481_I	0.742	0.76
924_N	993_F	0.741	0.75
518_I	523_S	0.741	0.75
17_D	75_E	0.740	0.75
55_V	59_K	0.740	0.75
248_A	571_T	0.740	0.75
520_N	523_S	0.739	0.75
364_K	440_L	0.739	0.75
240_H	269_A	0.738	0.75
123_S	126_T	0.738	0.75
25_L	37_L	0.738	0.75
547_D	553_K	0.738	0.75
125_Y	134_T	0.737	0.75
704_V	715_T	0.737	0.75
256_A	512_A	0.736	0.75
816_F	820_G	0.736	0.75
26_L	29_A	0.736	0.75
532_F	536_S	0.735	0.75
950_G	953_V	0.734	0.75
871_L	932_T	0.734	0.75
234_I	297_T	0.734	0.75
226_A	233_M	0.731	0.74
1112_W	1123_N	0.731	0.74
998_N	1055_T	0.731	0.74
143_L	146_D	0.731	0.74
147_P	202_K	0.730	0.74
232_Q	292_Q	0.730	0.74
161_V	190_F	0.730	0.74
703_K	734_V	0.730	0.74
160_E	164_H	0.730	0.74
5_H	100_L	0.730	0.74
736_Y	768_Y	0.729	0.74
975_K	978_I	0.728	0.74
156_C	258_D	0.728	0.74
659_E	927_D	0.727	0.74
8_T	26_L	0.727	0.74
673_E	859_L	0.727	0.74
522_I	525_Y	0.726	0.74
1134_Y	1165_D	0.726	0.74
121_E	602_M	0.726	0.74
55_V	68_F	0.726	0.74
286_D	291_D	0.726	0.74
19_T	253_F	0.725	0.74
165_L	218_C	0.725	0.74
1101_E	1135_A	0.725	0.74
732_T	736_Y	0.724	0.74
162_N	222_L	0.724	0.74
697_G	719_M	0.723	0.74
28_T	278_I	0.722	0.74
680_M	712_A	0.722	0.74
748_T	768_Y	0.722	0.74
948_G	982_G	0.722	0.74
700_S	725_G	0.720	0.73
1145_D	1169_F	0.720	0.73
740_L	746_E	0.720	0.73
1075_N	1079_S	0.719	0.73
103_A	149_H	0.718	0.73
681_A	701_V	0.717	0.73
638_I	857_I	0.716	0.73
115_L	135_V	0.716	0.73
642_L	667_P	0.716	0.73
244_P	281_R	0.715	0.73
878_L	926_A	0.715	0.73
645_L	663_K	0.714	0.73
49_L	622_M	0.714	0.73
644_Q	660_T	0.714	0.73
928_F	958_V	0.713	0.73
235_V	287_K	0.711	0.72
476_S	639_R	0.711	0.72
508_A	512_A	0.710	0.72
948_G	986_Q	0.710	0.72
5_H	240_H	0.710	0.72
5_H	38_A	0.710	0.72
634_A	877_C	0.709	0.72
371_T	379_L	0.708	0.72
1063_L	1066_L	0.708	0.72
73_G	102_L	0.707	0.72
212_S	215_Q	0.706	0.72
523_S	527_S	0.706	0.72
542_H	546_G	0.706	0.72
709_L	712_A	0.705	0.72
159_S	162_N	0.704	0.72
102_L	300_I	0.703	0.72
731_D	851_T	0.703	0.72
39_I	47_A	0.703	0.72
1009_L	1013_P	0.702	0.71
733_Y	768_Y	0.702	0.71
703_K	735_K	0.702	0.71
4_C	14_R	0.701	0.71
1056_L	1068_D	0.701	0.71
703_K	726_E	0.701	0.71
716_N	856_I	0.700	0.71
71_I	301_G	0.699	0.71
314_I	593_N	0.699	0.71
642_L	666_H	0.699	0.71
1146_S	1166_I	0.699	0.71
74_N	150_I	0.699	0.71
387_G	396_L	0.698	0.71
114_I	146_D	0.696	0.71
513_C	516_L	0.696	0.71
922_D	940_L	0.694	0.71
250_H	269_A	0.694	0.71
209_P	290_I	0.693	0.70
360_G	364_K	0.693	0.70
43_E	133_P	0.692	0.70
730_V	770_V	0.692	0.70
640_V	929_G	0.692	0.70
5_H	208_Q	0.692	0.70
682_G	851_T	0.690	0.70
642_L	670_I	0.689	0.70
559_I	573_L	0.689	0.70
565_Y	568_L	0.689	0.70
596_Y	600_N	0.688	0.70
678_W	681_A	0.688	0.70
529_M	547_D	0.688	0.70
1103_D	1109_I	0.687	0.70
993_F	996_F	0.687	0.70
686_I	698_H	0.687	0.70
536_S	539_P	0.687	0.70
243_R	246_D	0.686	0.70
361_F	371_T	0.686	0.70
790_D	815_L	0.685	0.70
32_M	243_R	0.685	0.70
981_K	985_I	0.685	0.70
450_Q	710_L	0.684	0.69
404_Y	469_I	0.684	0.69
997_G	1001_E	0.682	0.69
104_M	151_I	0.682	0.69
410_I	481_I	0.682	0.69
825_T	833_V	0.681	0.69
1000_Q	1049_S	0.681	0.69
123_S	133_P	0.681	0.69
813_E	834_W	0.681	0.69
582_R	603_M	0.681	0.69
870_P	914_R	0.680	0.69
871_L	937_N	0.679	0.69
593_N	599_S	0.679	0.69
4_C	300_I	0.679	0.69
1052_V	1072_S	0.677	0.69
25_L	276_D	0.677	0.69
536_S	543_C	0.677	0.69
410_I	629_L	0.676	0.69
99_F	194_C	0.676	0.69
352_Y	359_D	0.675	0.68
24_E	242_L	0.675	0.68
207_L	226_A	0.675	0.68
22_V	26_L	0.675	0.68
83_E	142_L	0.675	0.68
825_T	829_L	0.674	0.68
315_I	466_L	0.674	0.68
509_L	527_S	0.674	0.68
698_H	701_V	0.673	0.68
497_I	620_E	0.673	0.68
29_A	32_M	0.673	0.68
751_G	762_R	0.672	0.68
38_A	71_I	0.672	0.68
1147_L	1167_A	0.670	0.68
116_S	120_W	0.670	0.68
1199_G	1202_L	0.669	0.68
241_Y	247_R	0.669	0.68
20_N	276_D	0.669	0.68
923_I	992_C	0.669	0.68
76_A	115_L	0.669	0.68
644_Q	875_T	0.669	0.68
1198_I	1201_V	0.668	0.68
161_V	205_I	0.668	0.68
6_C	37_L	0.668	0.68
207_L	222_L	0.668	0.68
1193_E	1196_R	0.667	0.68
681_A	715_T	0.667	0.68
189_E	192_T	0.666	0.67
157_L	162_N	0.666	0.67
908_I	1064_F	0.666	0.67
564_Q	567_N	0.664	0.67
729_P	770_V	0.664	0.67
80_D	96_F	0.663	0.67
725_G	770_V	0.661	0.67
153_T	236_T	0.660	0.67
432_A	847_S	0.660	0.67
879_T	882_S	0.659	0.67
1147_L	1164_Y	0.659	0.67
1016_K	1020_S	0.659	0.67
118_Q	121_E	0.659	0.67
7_H	42_H	0.658	0.66
383_N	1165_D	0.658	0.66
595_E	598_K	0.658	0.66
415_W	425_V	0.657	0.66
370_L	379_L	0.657	0.66
292_Q	295_K	0.657	0.66
157_L	215_Q	0.655	0.66
251_Q	261_R	0.655	0.66
789_F	809_L	0.655	0.66
202_K	232_Q	0.655	0.66
29_A	279_H	0.655	0.66
681_A	862_L	0.654	0.66
603_M	611_I	0.654	0.66
506_K	532_F	0.653	0.66
711_E	737_K	0.653	0.66
104_M	305_E	0.652	0.66
923_I	943_L	0.652	0.66
255_N	258_D	0.651	0.66
726_E	772_D	0.651	0.66
883_G	951_D	0.650	0.66
259_G	515_G	0.649	0.65
958_V	963_Y	0.649	0.65
5_H	40_T	0.649	0.65
20_N	239_A	0.649	0.65
316_P	323_F	0.648	0.65
641_T	645_L	0.648	0.65
994_D	1055_T	0.648	0.65
1077_H	1081_D	0.648	0.65
358_E	386_L	0.646	0.65
863_N	868_Y	0.646	0.65
920_L	940_L	0.646	0.65
109_H	113_R	0.646	0.65
445_Q	860_Q	0.645	0.65
3_G	282_M	0.645	0.65
5_H	98_H	0.645	0.65
704_V	738_N	0.645	0.65
971_E	1041_F	0.645	0.65
408_R	413_I	0.644	0.65
596_Y	602_M	0.644	0.65
1012_E	1042_F	0.644	0.65
141_E	145_K	0.644	0.65
9_D	253_F	0.643	0.65
1151_Y	1162_A	0.642	0.65
789_F	813_E	0.642	0.65
53_R	60_K	0.642	0.65
758_R	765_K	0.642	0.65
207_L	233_M	0.641	0.64
78_L	143_L	0.641	0.64
562_V	565_Y	0.640	0.64
1104_N	1148_S	0.640	0.64
740_L	747_M	0.639	0.64
751_G	837_Q	0.639	0.64
386_L	441_L	0.639	0.64
294_I	298_M	0.638	0.64
5_H	17_D	0.638	0.64
692_F	697_G	0.637	0.64
323_F	348_E	0.636	0.64
799_K	805_K	0.635	0.64
1126_L	1138_S	0.635	0.64
217_Y	221_K	0.634	0.64
584_S	611_I	0.634	0.64
516_L	568_L	0.634	0.64
1114_T	1121_K	0.634	0.64
72_L	308_T	0.634	0.64
903_K	906_S	0.634	0.64
210_A	274_N	0.633	0.64
1130_E	1133_K	0.633	0.64
79_V	83_E	0.633	0.64
3_G	6_C	0.633	0.64
872_Y	937_N	0.632	0.63
665_I	670_I	0.631	0.63
1053_Y	1073_F	0.631	0.63
510_Q	523_S	0.630	0.63
810_K	813_E	0.629	0.63
242_L	246_D	0.629	0.63
758_R	762_R	0.629	0.63
1058_S	1061_D	0.628	0.63
1054_K	1057_K	0.628	0.63
927_D	958_V	0.627	0.63
362_E	366_K	0.627	0.63
1100_K	1112_W	0.627	0.63
7_H	206_E	0.627	0.63
104_M	149_H	0.627	0.63
484_A	487_E	0.626	0.63
505_S	530_I	0.626	0.63
185_L	188_H	0.625	0.63
1145_D	1172_L	0.625	0.63
729_P	732_T	0.625	0.63
751_G	829_L	0.625	0.63
988_I	1003_M	0.625	0.63
413_I	480_K	0.624	0.62
1181_P	1211_I	0.621	0.62
227_N	230_D	0.621	0.62
875_T	939_I	0.620	0.62
214_E	217_Y	0.620	0.62
1131_W	1135_A	0.620	0.62
226_A	230_D	0.620	0.62
1111_S	1128_I	0.620	0.62
367_T	371_T	0.619	0.62
74_N	101_M	0.619	0.62
789_F	834_W	0.619	0.62
1195_T	1199_G	0.618	0.62
450_Q	673_E	0.617	0.62
42_H	75_E	0.617	0.62
640_V	880_V	0.617	0.62
5_H	238_D	0.616	0.61
1129_K	1133_K	0.615	0.61
708_N	766_D	0.615	0.61
441_L	469_I	0.615	0.61
797_L	802_A	0.614	0.61
818_K	827_D	0.614	0.61
17_D	206_E	0.614	0.61
678_W	682_G	0.614	0.61
993_F	1002_I	0.614	0.61
123_S	136_K	0.614	0.61
317_K	349_Q	0.613	0.61
1098_F	1140_G	0.613	0.61
223_I	293_A	0.613	0.61
115_L	118_Q	0.612	0.61
1001_E	1047_Y	0.612	0.61
807_D	811_E	0.611	0.61
219_N	222_L	0.611	0.61
256_A	511_T	0.611	0.61
497_I	587_A	0.610	0.61
235_V	291_D	0.610	0.61
604_K	610_Y	0.610	0.61
52_I	306_D	0.609	0.61
297_T	300_I	0.609	0.61
241_Y	274_N	0.608	0.60
1192_Y	1195_T	0.608	0.60
815_L	818_K	0.608	0.60
377_K	381_R	0.608	0.60
25_L	29_A	0.608	0.60
461_K	792_K	0.608	0.60
295_K	299_L	0.607	0.60
708_N	713_A	0.607	0.60
543_C	546_G	0.607	0.60
136_K	141_E	0.607	0.60
106_P	307_Y	0.607	0.60
1204_R	1209_H	0.606	0.60
659_E	662_N	0.606	0.60
493_R	595_E	0.606	0.60
762_R	766_D	0.606	0.60
954_I	958_V	0.606	0.60
570_E	573_L	0.605	0.60
416_D	420_G	0.605	0.60
356_L	441_L	0.605	0.60
1110_K	1128_I	0.603	0.60
8_T	48_H	0.603	0.60
689_L	866_Y	0.603	0.60
238_D	250_H	0.603	0.60
875_T	932_T	0.602	0.60
1197_I	1201_V	0.602	0.60
982_G	986_Q	0.602	0.60
123_S	134_T	0.602	0.60
381_R	453_L	0.602	0.60
1191_E	1195_T	0.601	0.60
234_I	301_G	0.601	0.60
308_T	311_H	0.600	0.59
493_R	596_Y	0.600	0.59
483_K	486_R	0.600	0.59
201_D	303_M	0.600	0.59
852_L	856_I	0.599	0.59
1113_I	1144_M	0.599	0.59
77_Y	156_C	0.597	0.59
165_L	187_I	0.596	0.59
616_M	700_S	0.595	0.59
789_F	819_K	0.594	0.59
75_E	206_E	0.594	0.59
154_T	206_E	0.594	0.59
199_G	232_Q	0.594	0.59
474_E	639_R	0.593	0.59
1115_T	1122_L	0.592	0.58
1194_T	1197_I	0.592	0.58
414_I	425_V	0.591	0.58
255_N	265_S	0.591	0.58
1005_A	1044_F	0.591	0.58
700_S	730_V	0.591	0.58
256_A	515_G	0.591	0.58
990_G	993_F	0.591	0.58
123_S	132_V	0.590	0.58
207_L	235_V	0.590	0.58
436_L	439_Y	0.590	0.58
46_S	498_A	0.590	0.58
193_W	196_E	0.589	0.58
1056_L	1065_L	0.589	0.58
1052_V	1073_F	0.589	0.58
424_L	639_R	0.589	0.58
50_D	54_T	0.588	0.58
55_V	61_K	0.588	0.58
1152_N	1157_S	0.588	0.58
312_E	318_M	0.588	0.58
821_K	826_S	0.588	0.58
924_N	995_S	0.588	0.58
792_K	796_Y	0.588	0.58
708_N	716_N	0.587	0.58
166_L	218_C	0.586	0.58
1004_K	1047_Y	0.586	0.58
353_L	396_L	0.586	0.58
282_M	286_D	0.585	0.57
48_H	614_F	0.585	0.57
211_L	273_Q	0.584	0.57
1093_I	1147_L	0.584	0.57
260_E	266_F	0.583	0.57
499_T	583_S	0.583	0.57
820_G	830_L	0.583	0.57
248_A	570_E	0.583	0.57
316_P	320_L	0.583	0.57
520_N	527_S	0.583	0.57
369_E	372_R	0.583	0.57
166_L	214_E	0.582	0.57
963_Y	972_R	0.582	0.57
1194_T	1198_I	0.582	0.57
141_E	144_S	0.582	0.57
819_K	830_L	0.581	0.57
814_E	827_D	0.581	0.57
518_I	565_Y	0.581	0.57
251_Q	255_N	0.581	0.57
9_D	579_T	0.581	0.57
506_K	527_S	0.580	0.57
1167_A	1172_L	0.580	0.57
509_L	568_L	0.580	0.57
643_D	664_Y	0.580	0.57
280_E	284_Y	0.579	0.57
518_I	567_N	0.579	0.57
310_E	622_M	0.578	0.57
28_T	276_D	0.578	0.57
255_N	267_Y	0.578	0.57
1206_K	1210_A	0.578	0.57
733_Y	736_Y	0.577	0.56
970_I	984_V	0.577	0.56
695_E	1123_N	0.577	0.56
878_L	1064_F	0.577	0.56
162_N	165_L	0.576	0.56
78_L	194_C	0.576	0.56
681_A	712_A	0.576	0.56
736_Y	740_L	0.576	0.56
734_V	737_K	0.575	0.56
963_Y	973_M	0.575	0.56
1081_D	1167_A	0.575	0.56
235_V	286_D	0.575	0.56
534_R	539_P	0.574	0.56
1199_G	1203_D	0.574	0.56
998_N	1048_I	0.574	0.56
793_E	812_V	0.573	0.56
210_A	285_I	0.573	0.56
221_K	225_I	0.573	0.56
1134_Y	1163_K	0.572	0.56
210_A	237_T	0.572	0.56
540_L	569_K	0.572	0.56
871_L	916_I	0.572	0.56
79_V	134_T	0.571	0.56
994_D	999_R	0.571	0.56
34_Y	276_D	0.570	0.56
42_H	133_P	0.570	0.56
935_N	940_L	0.569	0.55
233_M	296_N	0.569	0.55
4_C	13_I	0.568	0.55
526_L	568_L	0.568	0.55
923_I	954_I	0.567	0.55
700_S	726_E	0.567	0.55
922_D	925_K	0.567	0.55
105_D	305_E	0.566	0.55
384_V	388_E	0.566	0.55
242_L	276_D	0.566	0.55
18_S	269_A	0.566	0.55
1089_G	1164_Y	0.566	0.55
220_K	224_D	0.566	0.55
600_N	619_S	0.566	0.55
660_T	665_I	0.566	0.55
438_N	469_I	0.565	0.55
159_S	236_T	0.565	0.55
839_K	843_G	0.565	0.55
971_E	1016_K	0.565	0.55
469_I	625_V	0.565	0.55
991_G	994_D	0.564	0.55
634_A	715_T	0.564	0.55
558_F	565_Y	0.564	0.55
809_L	834_W	0.563	0.55
713_A	851_T	0.563	0.55
779_Q	799_K	0.562	0.55
480_K	487_E	0.562	0.55
781_V	845_S	0.561	0.54
452_D	765_K	0.561	0.54
75_E	208_Q	0.560	0.54
254_L	257_K	0.560	0.54
700_S	851_T	0.560	0.54
614_F	618_D	0.560	0.54
445_Q	853_A	0.560	0.54
660_T	663_K	0.559	0.54
683_N	866_Y	0.559	0.54
1167_A	1171_K	0.559	0.54
154_T	191_I	0.558	0.54
816_F	834_W	0.558	0.54
225_I	229_Y	0.558	0.54
249_I	508_A	0.558	0.54
908_I	912_R	0.558	0.54
40_T	73_G	0.557	0.54
700_S	729_P	0.557	0.54
874_N	910_N	0.557	0.54
916_I	939_I	0.556	0.54
464_P	792_K	0.556	0.54
49_L	310_E	0.556	0.54
1134_Y	1137_G	0.556	0.54
590_I	932_T	0.556	0.54
1089_G	1147_L	0.555	0.54
806_E	809_L	0.555	0.54
318_M	412_N	0.555	0.54
540_L	547_D	0.554	0.53
106_P	309_I	0.554	0.53
540_L	573_L	0.554	0.53
530_I	534_R	0.554	0.53
354_L	379_L	0.554	0.53
377_K	452_D	0.553	0.53
969_F	1002_I	0.553	0.53
801_I	834_W	0.553	0.53
605_T	609_A	0.553	0.53
671_E	863_N	0.552	0.53
645_L	665_I	0.552	0.53
23_K	27_K	0.551	0.53
726_E	840_R	0.551	0.53
156_C	159_S	0.551	0.53
1019_L	1022_L	0.551	0.53
45_L	112_L	0.551	0.53
1125_C	1128_I	0.551	0.53
351_R	355_K	0.551	0.53
726_E	770_V	0.550	0.53
728_Q	840_R	0.550	0.53
793_E	796_Y	0.550	0.53
400_M	625_V	0.550	0.53
641_T	857_I	0.550	0.53
600_N	624_S	0.550	0.53
18_S	250_H	0.550	0.53
254_L	269_A	0.550	0.53
592_F	596_Y	0.549	0.53
436_L	449_M	0.549	0.53
52_I	59_K	0.549	0.53
3_G	34_Y	0.549	0.53
1057_K	1141_K	0.549	0.53
192_T	231_L	0.549	0.53
252_A	262_E	0.549	0.53
969_F	973_M	0.549	0.53
207_L	219_N	0.548	0.53
526_L	555_I	0.548	0.53
33_E	273_Q	0.548	0.53
39_I	48_H	0.548	0.53
750_Y	760_M	0.548	0.53
795_N	798_R	0.547	0.53
1200_T	1203_D	0.547	0.53
716_N	727_E	0.546	0.52
20_N	37_L	0.546	0.52
519_D	522_I	0.545	0.52
155_A	159_S	0.545	0.52
505_S	540_L	0.544	0.52
1053_Y	1141_K	0.544	0.52
229_Y	232_Q	0.544	0.52
107_K	146_D	0.543	0.52
539_P	543_C	0.543	0.52
789_F	799_K	0.543	0.52
928_F	954_I	0.543	0.52
42_H	238_D	0.543	0.52
568_L	572_A	0.542	0.52
357_I	362_E	0.541	0.52
71_I	1122_L	0.541	0.52
462_S	790_D	0.541	0.52
454_P	778_M	0.541	0.52
513_C	526_L	0.541	0.52
1091_L	1164_Y	0.540	0.52
784_K	793_E	0.539	0.51
618_D	621_A	0.539	0.51
687_M	906_S	0.538	0.51
1192_Y	1205_D	0.538	0.51
787_A	820_G	0.538	0.51
877_C	880_V	0.538	0.51
591_I	813_E	0.538	0.51
725_G	772_D	0.538	0.51
143_L	194_C	0.537	0.51
404_Y	441_L	0.537	0.51
204_F	232_Q	0.536	0.51
732_T	735_K	0.536	0.51
928_F	951_D	0.535	0.51
748_T	765_K	0.535	0.51
757_I	826_S	0.535	0.51
21_S	253_F	0.535	0.51
1092_V	1116_E	0.534	0.51
661_Y	665_I	0.534	0.51
315_I	318_M	0.534	0.51
751_G	785_D	0.534	0.51
83_E	136_K	0.533	0.51
642_L	864_L	0.533	0.51
49_L	618_D	0.533	0.51
255_N	262_E	0.532	0.51
270_C	274_N	0.532	0.51
122_N	141_E	0.532	0.51
994_D	998_N	0.532	0.51
787_A	838_F	0.532	0.51
119_A	133_P	0.531	0.50
218_C	221_K	0.531	0.50
736_Y	749_R	0.531	0.50
190_F	194_C	0.531	0.50
759_V	762_R	0.531	0.50
1192_Y	1196_R	0.531	0.50
420_G	477_K	0.531	0.50
503_E	511_T	0.530	0.50
508_A	573_L	0.530	0.50
817_F	830_L	0.529	0.50
594_D	599_S	0.529	0.50
563_E	567_N	0.529	0.50
1202_L	1205_D	0.529	0.50
362_E	367_T	0.529	0.50
362_E	370_L	0.529	0.50
965_D	996_F	0.528	0.50
806_E	839_K	0.528	0.50
511_T	514_R	0.528	0.50
321_P	351_R	0.527	0.50
147_P	199_G	0.527	0.50
533_E	546_G	0.526	0.50
462_S	799_K	0.526	0.50
207_L	300_I	0.526	0.50
675_D	863_N	0.526	0.50
701_V	716_N	0.525	0.50
464_P	799_K	0.525	0.50
734_V	738_N	0.525	0.50
249_I	575_I	0.525	0.50
381_R	449_M	0.525	0.50
1000_Q	1048_I	0.525	0.50
384_V	471_I	0.524	0.50
475_G	636_D	0.523	0.49
26_L	68_F	0.522	0.49
378_I	439_Y	0.522	0.49
491_D	610_Y	0.521	0.49
157_L	214_E	0.521	0.49
401_S	506_K	0.521	0.49
460_H	465_D	0.521	0.49
796_Y	808_V	0.521	0.49
404_Y	437_V	0.520	0.49
287_K	290_I	0.520	0.49
124_F	134_T	0.520	0.49
714_V	773_T	0.520	0.49
731_D	770_V	0.520	0.49
35_K	68_F	0.519	0.49
362_E	379_L	0.519	0.49
802_A	866_Y	0.518	0.49
148_G	202_K	0.517	0.49
500_F	615_N	0.517	0.49
557_E	560_R	0.517	0.49
27_K	30_V	0.516	0.48
209_P	219_N	0.516	0.48
600_N	614_F	0.516	0.48
789_F	793_E	0.516	0.48
571_T	574_K	0.515	0.48
361_F	366_K	0.515	0.48
312_E	316_P	0.515	0.48
282_M	285_I	0.515	0.48
209_P	286_D	0.514	0.48
43_E	123_S	0.514	0.48
451_Y	713_A	0.514	0.48
871_L	936_N	0.514	0.48
295_K	298_M	0.514	0.48
793_E	797_L	0.514	0.48
36_G	71_I	0.514	0.48
779_Q	873_W	0.514	0.48
748_T	751_G	0.513	0.48
1065_L	1070_S	0.513	0.48
925_K	995_S	0.513	0.48
1179_G	1211_I	0.513	0.48
809_L	838_F	0.513	0.48
634_A	861_E	0.513	0.48
424_L	475_G	0.513	0.48
195_I	232_Q	0.512	0.48
8_T	14_R	0.512	0.48
241_Y	269_A	0.512	0.48
361_F	365_L	0.512	0.48
36_G	298_M	0.512	0.48
195_I	203_F	0.511	0.48
102_L	304_I	0.511	0.48
746_E	749_R	0.511	0.48
156_C	215_Q	0.511	0.48
76_A	119_A	0.511	0.48
473_T	629_L	0.510	0.48
7_H	236_T	0.510	0.48
1105_K	1127_L	0.510	0.48
1184_W	1205_D	0.510	0.48
154_T	236_T	0.510	0.48
480_K	483_K	0.510	0.48
496_Q	589_V	0.510	0.48
978_I	983_Q	0.509	0.48
531_P	543_C	0.509	0.48
970_I	988_I	0.509	0.48
1093_I	1145_D	0.508	0.47
15_L	581_K	0.508	0.47
677_L	858_A	0.508	0.47
614_F	622_M	0.507	0.47
493_R	592_F	0.507	0.47
404_Y	432_A	0.507	0.47
712_A	855_S	0.507	0.47
465_D	809_L	0.506	0.47
420_G	747_M	0.506	0.47
149_H	155_A	0.505	0.47
949_I	953_V	0.505	0.47
1153_D	1157_S	0.505	0.47
366_K	370_L	0.505	0.47
137_K	190_F	0.505	0.47
1099_K	1111_S	0.504	0.47
838_F	843_G	0.504	0.47
493_R	594_D	0.504	0.47
956_H	978_I	0.504	0.47
736_Y	747_M	0.504	0.47
704_V	730_V	0.504	0.47
323_F	347_D	0.504	0.47
282_M	294_I	0.504	0.47
8_T	29_A	0.503	0.47
731_D	735_K	0.503	0.47
295_K	675_D	0.503	0.47
50_D	733_Y	0.503	0.47
1001_E	1046_D	0.503	0.47
245_E	1072_S	0.502	0.47
789_F	800_S	0.502	0.47
417_D	423_S	0.502	0.47
77_Y	240_H	0.502	0.47
587_A	617_G	0.502	0.47
678_W	692_F	0.501	0.47
700_S	728_Q	0.501	0.47
30_V	33_E	0.501	0.47
485_L	591_I	0.501	0.47
264_D	268_E	0.500	0.46
866_Y	870_P	0.500	0.46
733_Y	739_N	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hnhA	1	0.6774	100	0.337	Contact Map
3f2bA	1	0.6031	100	0.471	Contact Map
4gx8A	1	0.2023	100	0.861	Contact Map
3e38A	4	0.213	100	0.902	Contact Map
3dcpA	1	0.1808	100	0.941	Contact Map
2yxoA	3	0.1847	99.9	0.945	Contact Map
3b0xA	1	0.1739	99.9	0.952	Contact Map
2w9mA	1	0.1732	99.9	0.953	Contact Map
3o0fA	1	0.177	99.8	0.955	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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