YOJA - BACSU - GREMLIN Contacts

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YOJA - Uncharacterized permease YojA

UniProt:	O31862	Sequences: MPILIVAVGVLILLFLIIKVKLNTFVSLIVVSFLVAIGLGMDINKIVLSIETGIGGQLGHLALVFGLGAMLGRLVSDAGGGYRIAITLIDKFGRKRIQAAVVVASFIIGIALFFEVGLVLLIPIVYAIAKELKMPFLYLGIPMAAALNVTHGFLPPHPAPTAISVAYGAHIGQVLLFGIIIAVPTTVIAGPLFNKFAMKRFPGAYQKHGNLSGLGPRKEFQLDETPGFAISAVTSLFPVIFMAMATIFSLLLSEHSKGKDIIEFIGTPGTAMLISLLLALYTMGYARKISMQEIGRSISESISQIAMMLLIIGGGGAFKQVLIDGGVGDYVADFFRQTNMSPLFVAWTIAAVLRLCLGSATVAALTTAGMAAPLMEAGSVNPALMVLATGAGSVIACHVNDAGFWMVKEFFGLSMKETFQTWTLLTTVLSVTGLGCVLLAGLVM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	444 (420)
Sequences:	5308 (3563)
Seq/√Len:	173.9

ECOLI - YJHF GNTP GNTU YGBN IDNT GNTT DSDX
BACSU - YOJA GNTP YXJC
HALSA - Q9HNF6 Q9HNR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
196_F	200_R	3.625	1.00
300_E	303_S	3.342	1.00
290_S	293_E	3.154	1.00
9_G	318_F	3.134	1.00
268_P	272_M	3.124	1.00
180_I	184_P	3.098	1.00
12_I	34_L	3.049	1.00
320_Q	324_D	3.036	1.00
9_G	35_V	2.904	1.00
87_T	228_F	2.863	1.00
77_D	297_S	2.851	1.00
329_D	333_D	2.802	1.00
237_F	278_L	2.784	1.00
414_S	417_E	2.752	1.00
228_F	232_A	2.751	1.00
171_I	175_L	2.745	1.00
49_S	324_D	2.684	1.00
87_T	91_K	2.574	1.00
344_F	434_L	2.523	1.00
234_T	238_P	2.490	1.00
347_W	430_S	2.489	1.00
193_F	197_A	2.449	1.00
11_L	15_F	2.411	1.00
42_D	45_K	2.388	1.00
52_T	56_G	2.387	1.00
170_H	175_L	2.319	1.00
268_P	271_A	2.318	1.00
200_R	204_A	2.287	1.00
87_T	90_D	2.281	1.00
435_G	439_L	2.273	1.00
333_D	336_R	2.265	1.00
227_G	230_I	2.237	1.00
172_G	175_L	2.219	1.00
229_A	233_V	2.194	1.00
427_T	431_V	2.194	1.00
48_L	52_T	2.187	1.00
431_V	435_G	2.154	1.00
182_A	185_T	2.144	1.00
15_F	19_K	2.076	1.00
170_H	173_Q	2.070	1.00
192_L	196_F	2.046	1.00
82_Y	86_I	2.044	1.00
177_F	180_I	2.025	1.00
199_K	202_P	2.006	1.00
167_Y	389_T	2.000	1.00
231_S	234_T	1.929	1.00
204_A	207_K	1.922	1.00
350_A	367_T	1.912	1.00
197_A	200_R	1.911	1.00
198_M	202_P	1.839	1.00
338_T	341_S	1.832	1.00
77_D	293_E	1.818	1.00
198_M	201_F	1.817	1.00
176_L	179_I	1.812	1.00
181_I	185_T	1.803	1.00
171_I	176_L	1.755	1.00
173_Q	176_L	1.742	1.00
12_I	31_V	1.732	1.00
175_L	178_G	1.731	1.00
330_Y	334_F	1.726	1.00
197_A	201_F	1.725	1.00
420_Q	424_L	1.725	1.00
238_P	242_M	1.709	1.00
45_K	48_L	1.708	1.00
234_T	242_M	1.704	1.00
193_F	196_F	1.704	1.00
179_I	182_A	1.696	1.00
188_I	192_L	1.675	1.00
177_F	181_I	1.664	1.00
346_A	389_T	1.664	1.00
351_A	395_I	1.663	1.00
42_D	46_I	1.658	1.00
379_S	382_P	1.655	1.00
375_M	385_M	1.649	1.00
163_I	364_A	1.637	1.00
172_G	176_L	1.631	1.00
170_H	174_V	1.627	1.00
178_G	182_A	1.627	1.00
355_L	396_A	1.620	1.00
201_F	205_Y	1.620	1.00
192_L	195_K	1.618	1.00
169_A	174_V	1.615	1.00
198_M	204_A	1.605	1.00
176_L	180_I	1.594	1.00
140_G	411_F	1.593	1.00
178_G	184_P	1.589	1.00
235_S	242_M	1.587	1.00
73_R	77_D	1.575	1.00
199_K	203_G	1.560	1.00
152_G	394_V	1.545	1.00
99_A	191_P	1.543	1.00
94_R	131_E	1.528	1.00
179_I	183_V	1.513	1.00
178_G	181_I	1.498	1.00
192_L	200_R	1.485	1.00
202_P	206_Q	1.481	1.00
193_F	200_R	1.473	1.00
101_V	105_S	1.471	1.00
5_I	38_G	1.467	1.00
424_L	428_V	1.462	1.00
277_L	281_Y	1.458	1.00
196_F	199_K	1.458	1.00
70_M	298_I	1.453	1.00
49_S	320_Q	1.444	1.00
272_M	276_L	1.439	1.00
241_F	274_I	1.439	1.00
133_K	204_A	1.426	1.00
261_I	265_I	1.423	1.00
193_F	201_F	1.411	1.00
105_S	108_I	1.399	1.00
436_C	440_A	1.394	1.00
195_K	199_K	1.393	1.00
200_R	203_G	1.384	1.00
115_E	402_A	1.382	1.00
238_P	246_T	1.381	1.00
39_L	42_D	1.379	1.00
83_R	87_T	1.374	1.00
170_H	176_L	1.373	1.00
263_E	266_G	1.363	1.00
175_L	180_I	1.357	1.00
22_L	27_S	1.356	1.00
190_G	193_F	1.347	1.00
272_M	275_S	1.344	1.00
226_P	231_S	1.339	1.00
438_L	441_G	1.337	1.00
203_G	206_Q	1.337	1.00
69_A	298_I	1.333	1.00
293_E	296_R	1.329	1.00
175_L	179_I	1.327	1.00
12_I	16_L	1.322	1.00
180_I	185_T	1.316	1.00
10_V	13_L	1.315	1.00
228_F	231_S	1.314	1.00
262_I	266_G	1.308	1.00
395_I	430_S	1.291	1.00
235_S	238_P	1.281	1.00
101_V	104_A	1.278	1.00
13_L	31_V	1.277	1.00
230_I	233_V	1.274	1.00
115_E	312_I	1.264	1.00
166_A	368_A	1.261	1.00
319_K	323_I	1.256	1.00
81_G	85_A	1.244	1.00
230_I	234_T	1.244	1.00
261_I	266_G	1.231	1.00
200_R	206_Q	1.228	1.00
54_I	62_A	1.225	1.00
73_R	297_S	1.225	1.00
82_Y	223_D	1.224	1.00
296_R	300_E	1.214	1.00
200_R	207_K	1.210	1.00
174_V	386_V	1.207	1.00
202_P	205_Y	1.203	1.00
269_G	273_L	1.200	1.00
78_A	283_M	1.198	1.00
229_A	234_T	1.197	1.00
194_N	200_R	1.195	1.00
261_I	267_T	1.194	1.00
53_G	320_Q	1.186	1.00
114_F	403_G	1.184	1.00
391_A	437_V	1.183	1.00
50_I	317_A	1.167	1.00
181_I	440_A	1.161	1.00
391_A	433_G	1.152	1.00
395_I	427_T	1.143	1.00
179_I	184_P	1.136	1.00
378_G	382_P	1.134	1.00
197_A	204_A	1.133	1.00
195_K	198_M	1.133	1.00
80_G	231_S	1.133	1.00
178_G	185_T	1.129	1.00
241_F	245_A	1.127	1.00
355_L	395_I	1.127	1.00
246_T	249_S	1.125	1.00
102_V	186_T	1.121	1.00
245_A	249_S	1.117	1.00
114_F	117_G	1.117	1.00
425_L	429_L	1.116	1.00
270_T	274_I	1.111	1.00
237_F	275_S	1.111	1.00
242_M	246_T	1.107	1.00
6_V	10_V	1.105	1.00
86_I	131_E	1.102	1.00
359_S	362_V	1.102	1.00
86_I	90_D	1.102	1.00
416_K	420_Q	1.101	1.00
275_S	279_A	1.101	1.00
312_I	402_A	1.100	1.00
229_A	232_A	1.097	1.00
118_L	410_F	1.097	1.00
199_K	204_A	1.093	1.00
292_Q	296_R	1.092	1.00
199_K	207_K	1.086	1.00
397_C	401_D	1.086	1.00
196_F	204_A	1.086	1.00
271_A	276_L	1.085	1.00
278_L	282_T	1.084	1.00
191_P	194_N	1.083	1.00
408_K	418_T	1.078	1.00
173_Q	177_F	1.075	1.00
195_K	200_R	1.074	1.00
9_G	34_L	1.073	1.00
194_N	198_M	1.073	1.00
164_S	168_G	1.066	1.00
190_G	196_F	1.065	1.00
231_S	238_P	1.047	1.00
177_F	182_A	1.047	1.00
25_F	310_L	1.047	1.00
261_I	264_F	1.044	0.99
190_G	194_N	1.031	0.99
188_I	196_F	1.023	0.99
93_G	100_A	1.022	0.99
130_K	136_F	1.021	0.99
116_V	119_V	1.012	0.99
177_F	383_A	1.001	0.99
234_T	250_L	1.000	0.99
173_Q	179_I	0.998	0.99
227_G	231_S	0.998	0.99
74_L	279_A	0.997	0.99
198_M	206_Q	0.995	0.99
34_L	38_G	0.993	0.99
397_C	422_W	0.984	0.99
376_E	382_P	0.984	0.99
190_G	195_K	0.977	0.99
145_A	190_G	0.972	0.99
150_T	154_L	0.970	0.99
233_V	237_F	0.969	0.99
268_P	273_L	0.968	0.99
326_G	329_D	0.968	0.99
150_T	157_H	0.965	0.99
182_A	186_T	0.965	0.99
396_A	423_T	0.957	0.99
360_A	397_C	0.954	0.99
44_N	48_L	0.952	0.99
27_S	31_V	0.950	0.99
193_F	428_V	0.950	0.99
101_V	107_I	0.945	0.99
433_G	437_V	0.944	0.99
195_K	203_G	0.940	0.99
387_L	437_V	0.938	0.99
247_I	251_L	0.938	0.99
268_P	279_A	0.937	0.99
320_Q	323_I	0.935	0.99
240_I	244_M	0.932	0.99
171_I	174_V	0.932	0.99
201_F	204_A	0.931	0.99
233_V	282_T	0.927	0.99
181_I	184_P	0.927	0.99
116_V	159_A	0.923	0.99
417_E	420_Q	0.921	0.99
77_D	300_E	0.921	0.99
248_F	252_L	0.919	0.99
174_V	178_G	0.915	0.99
220_F	224_E	0.915	0.99
196_F	201_F	0.913	0.99
180_I	183_V	0.910	0.99
364_A	393_S	0.910	0.99
175_L	184_P	0.910	0.99
194_N	201_F	0.909	0.99
169_A	173_Q	0.909	0.99
184_P	188_I	0.908	0.99
191_P	195_K	0.908	0.99
305_I	309_L	0.908	0.99
289_I	294_I	0.904	0.99
227_G	233_V	0.903	0.99
438_L	442_L	0.899	0.98
434_L	438_L	0.897	0.98
247_I	250_L	0.897	0.98
264_F	267_T	0.892	0.98
266_G	279_A	0.890	0.98
171_I	178_G	0.889	0.98
228_F	235_S	0.887	0.98
354_R	401_D	0.882	0.98
341_S	344_F	0.879	0.98
141_I	145_A	0.877	0.98
193_F	198_M	0.876	0.98
347_W	434_L	0.874	0.98
148_N	426_T	0.871	0.98
84_I	231_S	0.869	0.98
222_L	225_T	0.868	0.98
49_S	53_G	0.863	0.98
169_A	172_G	0.861	0.98
41_M	49_S	0.861	0.98
35_V	318_F	0.857	0.98
149_V	182_A	0.856	0.98
134_M	138_Y	0.856	0.98
213_G	216_P	0.855	0.98
196_F	202_P	0.854	0.98
16_L	22_L	0.854	0.98
246_T	250_L	0.853	0.98
387_L	391_A	0.852	0.98
363_A	401_D	0.852	0.98
237_F	241_F	0.852	0.98
415_M	419_F	0.848	0.98
113_F	116_V	0.846	0.98
426_T	429_L	0.845	0.98
33_F	270_T	0.845	0.98
197_A	207_K	0.845	0.98
279_A	283_M	0.842	0.98
86_I	225_T	0.826	0.97
177_F	387_L	0.825	0.97
7_A	11_L	0.822	0.97
83_R	228_F	0.820	0.97
57_Q	316_G	0.820	0.97
189_A	194_N	0.818	0.97
31_V	34_L	0.816	0.97
234_T	282_T	0.812	0.97
280_L	283_M	0.812	0.97
101_V	108_I	0.812	0.97
108_I	121_L	0.810	0.97
32_S	36_A	0.809	0.97
35_V	321_V	0.808	0.97
117_G	147_L	0.808	0.97
177_F	184_P	0.807	0.97
160_P	164_S	0.807	0.97
179_I	185_T	0.803	0.97
223_D	231_S	0.803	0.97
384_L	440_A	0.801	0.97
403_G	407_V	0.801	0.97
383_A	387_L	0.799	0.97
270_T	275_S	0.799	0.97
144_A	404_F	0.798	0.97
162_A	365_L	0.793	0.97
39_L	325_G	0.792	0.97
220_F	223_D	0.792	0.97
104_A	108_I	0.790	0.97
262_I	265_I	0.789	0.97
372_A	376_E	0.788	0.96
271_A	279_A	0.781	0.96
91_K	95_K	0.778	0.96
193_F	424_L	0.778	0.96
276_L	280_L	0.778	0.96
63_L	67_L	0.778	0.96
172_G	177_F	0.777	0.96
432_T	436_C	0.773	0.96
354_R	360_A	0.773	0.96
373_P	378_G	0.771	0.96
161_T	164_S	0.767	0.96
178_G	186_T	0.763	0.96
222_L	226_P	0.763	0.96
52_T	55_G	0.763	0.96
181_I	436_C	0.761	0.96
175_L	182_A	0.761	0.96
418_T	422_W	0.760	0.96
103_V	107_I	0.758	0.96
198_M	205_Y	0.755	0.96
245_A	250_L	0.755	0.96
176_L	181_I	0.753	0.95
110_I	113_F	0.750	0.95
109_G	150_T	0.747	0.95
109_G	113_F	0.746	0.95
174_V	177_F	0.744	0.95
94_R	132_L	0.744	0.95
106_F	110_I	0.743	0.95
190_G	197_A	0.741	0.95
226_P	234_T	0.739	0.95
10_V	17_I	0.735	0.95
189_A	193_F	0.734	0.95
192_L	199_K	0.734	0.95
117_G	157_H	0.732	0.95
360_A	402_A	0.732	0.95
166_A	369_G	0.727	0.95
153_F	433_G	0.724	0.94
270_T	273_L	0.723	0.94
16_L	27_S	0.722	0.94
360_A	393_S	0.722	0.94
423_T	427_T	0.721	0.94
384_L	437_V	0.720	0.94
439_L	442_L	0.716	0.94
104_A	107_I	0.714	0.94
429_L	433_G	0.714	0.94
5_I	39_L	0.713	0.94
243_A	246_T	0.713	0.94
421_T	424_L	0.711	0.94
432_T	435_G	0.711	0.94
193_F	202_P	0.711	0.94
194_N	197_A	0.710	0.94
194_N	199_K	0.707	0.94
276_L	282_T	0.707	0.94
266_G	271_A	0.705	0.94
231_S	242_M	0.705	0.94
248_F	251_L	0.703	0.93
354_R	397_C	0.702	0.93
201_F	206_Q	0.700	0.93
239_V	242_M	0.699	0.93
227_G	235_S	0.699	0.93
12_I	15_F	0.697	0.93
280_L	298_I	0.696	0.93
280_L	294_I	0.696	0.93
173_Q	178_G	0.696	0.93
5_I	9_G	0.694	0.93
231_S	250_L	0.692	0.93
172_G	179_I	0.692	0.93
5_I	31_V	0.692	0.93
109_G	112_L	0.688	0.93
226_P	230_I	0.688	0.93
96_R	106_F	0.687	0.93
23_N	26_V	0.686	0.93
229_A	238_P	0.685	0.93
222_L	227_G	0.684	0.93
290_S	294_I	0.683	0.92
196_F	207_K	0.681	0.92
344_F	438_L	0.679	0.92
180_I	202_P	0.678	0.92
10_V	14_L	0.677	0.92
202_P	207_K	0.675	0.92
270_T	276_L	0.675	0.92
191_P	198_M	0.675	0.92
354_R	363_A	0.667	0.92
237_F	240_I	0.666	0.92
279_A	282_T	0.664	0.91
244_M	247_I	0.662	0.91
170_H	179_I	0.661	0.91
171_I	179_I	0.658	0.91
125_V	143_M	0.658	0.91
41_M	45_K	0.657	0.91
73_R	300_E	0.657	0.91
373_P	377_A	0.657	0.91
146_A	150_T	0.656	0.91
148_N	394_V	0.654	0.91
196_F	203_G	0.652	0.91
48_L	51_E	0.652	0.91
189_A	192_L	0.651	0.91
179_I	186_T	0.651	0.91
115_E	118_L	0.647	0.90
267_T	272_M	0.647	0.90
191_P	196_F	0.646	0.90
221_Q	337_Q	0.645	0.90
9_G	13_L	0.645	0.90
230_I	238_P	0.644	0.90
350_A	393_S	0.644	0.90
228_F	242_M	0.643	0.90
270_T	283_M	0.643	0.90
16_L	30_V	0.643	0.90
185_T	432_T	0.643	0.90
102_V	106_F	0.643	0.90
243_A	247_I	0.642	0.90
200_R	205_Y	0.642	0.90
171_I	182_A	0.641	0.90
26_V	276_L	0.640	0.90
176_L	184_P	0.639	0.90
177_F	183_V	0.639	0.90
102_V	105_S	0.638	0.90
8_V	12_I	0.638	0.90
363_A	367_T	0.637	0.90
397_C	426_T	0.637	0.90
364_A	367_T	0.636	0.90
67_L	403_G	0.636	0.90
73_R	76_S	0.634	0.89
357_L	362_V	0.632	0.89
267_T	276_L	0.631	0.89
267_T	270_T	0.630	0.89
114_F	118_L	0.629	0.89
129_A	134_M	0.629	0.89
340_M	344_F	0.629	0.89
184_P	436_C	0.628	0.89
238_P	241_F	0.627	0.89
54_I	57_Q	0.626	0.89
115_E	119_V	0.626	0.89
47_V	51_E	0.626	0.89
174_V	383_A	0.625	0.89
190_G	200_R	0.625	0.89
233_V	240_I	0.624	0.89
50_I	53_G	0.624	0.89
96_R	102_V	0.624	0.89
178_G	183_V	0.621	0.88
399_V	419_F	0.619	0.88
362_V	366_T	0.619	0.88
181_I	387_L	0.615	0.88
249_S	263_E	0.614	0.88
75_V	80_G	0.613	0.88
189_A	432_T	0.612	0.88
5_I	8_V	0.611	0.88
140_G	413_L	0.611	0.88
228_F	234_T	0.611	0.88
135_P	201_F	0.609	0.87
192_L	197_A	0.609	0.87
422_W	426_T	0.609	0.87
169_A	175_L	0.606	0.87
103_V	106_F	0.606	0.87
271_A	282_T	0.606	0.87
343_L	380_V	0.605	0.87
109_G	157_H	0.605	0.87
203_G	207_K	0.605	0.87
269_G	272_M	0.605	0.87
58_L	313_G	0.604	0.87
265_I	269_G	0.604	0.87
88_L	92_F	0.603	0.87
335_F	349_I	0.600	0.87
96_R	100_A	0.600	0.87
40_G	44_N	0.600	0.87
40_G	45_K	0.598	0.87
346_A	371_A	0.597	0.86
151_H	155_P	0.596	0.86
351_A	355_L	0.596	0.86
70_M	294_I	0.595	0.86
189_A	196_F	0.594	0.86
214_L	218_K	0.594	0.86
330_Y	333_D	0.594	0.86
229_A	251_L	0.592	0.86
109_G	114_F	0.591	0.86
70_M	275_S	0.591	0.86
244_M	249_S	0.591	0.86
277_L	282_T	0.590	0.86
331_V	349_I	0.590	0.86
357_L	366_T	0.588	0.86
231_S	235_S	0.588	0.86
153_F	391_A	0.588	0.86
191_P	200_R	0.587	0.86
262_I	267_T	0.584	0.85
264_F	268_P	0.583	0.85
217_R	221_Q	0.579	0.85
236_L	243_A	0.578	0.85
189_A	200_R	0.578	0.85
351_A	430_S	0.578	0.85
157_H	364_A	0.577	0.85
109_G	119_V	0.577	0.85
52_T	324_D	0.576	0.84
268_P	276_L	0.574	0.84
112_L	119_V	0.574	0.84
33_F	217_R	0.573	0.84
96_R	99_A	0.572	0.84
345_V	375_M	0.571	0.84
214_L	217_R	0.570	0.84
173_Q	383_A	0.570	0.84
423_T	430_S	0.570	0.84
197_A	202_P	0.570	0.84
145_A	425_L	0.569	0.84
188_I	191_P	0.568	0.84
188_I	432_T	0.567	0.84
355_L	423_T	0.566	0.83
378_G	381_N	0.566	0.83
248_F	262_I	0.566	0.83
284_G	288_K	0.564	0.83
44_N	47_V	0.563	0.83
238_P	243_A	0.562	0.83
138_Y	142_P	0.561	0.83
194_N	203_G	0.559	0.83
346_A	350_A	0.558	0.83
41_M	46_I	0.558	0.83
273_L	277_L	0.558	0.83
421_T	425_L	0.557	0.82
195_K	207_K	0.556	0.82
52_T	320_Q	0.555	0.82
83_R	227_G	0.555	0.82
51_E	75_V	0.551	0.82
239_V	243_A	0.550	0.82
154_L	157_H	0.550	0.82
83_R	225_T	0.549	0.82
189_A	198_M	0.548	0.81
63_L	66_G	0.548	0.81
278_L	281_Y	0.548	0.81
80_G	83_R	0.546	0.81
112_L	272_M	0.546	0.81
234_T	241_F	0.545	0.81
404_F	408_K	0.544	0.81
350_A	363_A	0.543	0.81
224_E	230_I	0.543	0.81
91_K	94_R	0.542	0.81
7_A	435_G	0.542	0.81
41_M	325_G	0.542	0.81
67_L	158_P	0.542	0.81
141_I	425_L	0.540	0.80
375_M	382_P	0.538	0.80
174_V	179_I	0.536	0.80
184_P	196_F	0.535	0.80
145_A	149_V	0.534	0.80
396_A	419_F	0.533	0.80
227_G	234_T	0.532	0.80
40_G	43_I	0.530	0.79
53_G	56_G	0.530	0.79
63_L	269_G	0.529	0.79
228_F	233_V	0.529	0.79
174_V	180_I	0.529	0.79
396_A	427_T	0.529	0.79
384_L	441_G	0.528	0.79
38_G	45_K	0.527	0.79
116_V	312_I	0.527	0.79
269_G	279_A	0.527	0.79
245_A	251_L	0.527	0.79
83_R	231_S	0.526	0.79
233_V	238_P	0.526	0.79
398_H	426_T	0.525	0.79
157_H	312_I	0.524	0.78
232_A	236_L	0.523	0.78
236_L	244_M	0.522	0.78
8_V	11_L	0.521	0.78
222_L	229_A	0.519	0.78
190_G	201_F	0.517	0.78
436_C	439_L	0.517	0.78
122_I	411_F	0.517	0.78
224_E	228_F	0.517	0.78
226_P	238_P	0.516	0.77
227_G	244_M	0.516	0.77
117_G	121_L	0.516	0.77
106_F	149_V	0.515	0.77
353_L	357_L	0.515	0.77
214_L	222_L	0.514	0.77
185_T	436_C	0.514	0.77
284_G	294_I	0.514	0.77
398_H	421_T	0.514	0.77
367_T	389_T	0.514	0.77
226_P	240_I	0.514	0.77
197_A	203_G	0.513	0.77
125_V	129_A	0.513	0.77
311_I	365_L	0.513	0.77
219_E	222_L	0.512	0.77
45_K	49_S	0.512	0.77
96_R	108_I	0.511	0.77
112_L	319_K	0.511	0.77
368_A	389_T	0.511	0.77
177_F	185_T	0.510	0.77
272_M	280_L	0.510	0.77
90_D	192_L	0.509	0.76
105_S	121_L	0.509	0.76
296_R	303_S	0.508	0.76
237_F	274_I	0.507	0.76
136_F	140_G	0.507	0.76
169_A	176_L	0.506	0.76
113_F	159_A	0.506	0.76
244_M	248_F	0.505	0.76
272_M	279_A	0.505	0.76
13_L	356_C	0.505	0.76
331_V	356_C	0.504	0.76
150_T	160_P	0.504	0.76
129_A	139_L	0.504	0.76
232_A	235_S	0.503	0.76
351_A	396_A	0.502	0.76
195_K	201_F	0.501	0.75
90_D	293_E	0.500	0.75

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.9797	100	0.573	Contact Map
4r0cA	3	0.9662	100	0.601	Contact Map
4f35D	2	0.8896	100	0.634	Contact Map
2cfqA	1	0.8266	78.4	0.945	Contact Map
4pd6A	3	0.7568	67.2	0.949	Contact Map
2nwlA	3	0.7477	51.5	0.954	Contact Map
3aqpA	1	0.3266	44.3	0.956	Contact Map
4dx5A	3	0.3559	40.9	0.957	Contact Map
3qnqA	2	0.4617	37.6	0.958	Contact Map
4m64A	1	0.8739	37.3	0.958	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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