GREMLIN Database
YOJF - Uncharacterized protein YojF
UniProt: O31858 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 116 (114)
Sequences: 199 (136)
Seq/√Len: 12.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
19_R111_E5.3451.00
87_D91_R4.2881.00
52_V76_I4.1751.00
4_I81_L3.9200.99
9_V59_I3.2610.98
13_L57_A3.0300.97
21_V109_I2.7630.94
20_P51_K2.5630.91
20_P53_T2.3790.88
25_L78_A2.2900.86
45_A78_A2.2590.85
25_L47_I1.9680.76
14_E54_Y1.9580.75
23_I76_I1.8900.73
40_N43_V1.8300.70
43_V83_E1.8170.70
2_K22_Y1.7540.67
63_G79_E1.7350.66
67_V94_M1.7340.66
98_L102_K1.7170.65
83_E102_K1.5740.58
5_I8_D1.4390.51
64_P104_A1.4260.50
41_M104_A1.3160.45
29_T48_R1.3110.45
54_Y109_I1.2160.40
55_H72_E1.2070.39
56_Q76_I1.2040.39
64_P83_E1.1900.38
13_L99_P1.1650.37
27_T93_L1.1640.37
25_L45_A1.1530.37
46_Y73_E1.1270.35
17_A57_A1.1190.35
79_E97_H1.1190.35
23_I53_T1.1170.35
87_D90_N1.1090.35
59_I79_E1.0880.34
17_A54_Y1.0750.33
27_T48_R1.0730.33
44_V105_I1.0630.32
60_K64_P1.0210.31
65_Y81_L1.0090.30
70_K92_L1.0040.30
31_S97_H1.0010.30
78_A105_I0.9990.30
16_Y90_N0.9990.30
40_N104_A0.9970.30
29_T42_T0.9940.29
13_L50_A0.9940.29
81_L100_G0.9940.29
51_K72_E0.9900.29
21_V53_T0.9770.29
38_E55_H0.9770.29
40_N102_K0.9550.28
56_Q81_L0.9470.27
29_T44_V0.9340.27
12_S86_V0.9320.27
16_Y21_V0.9320.27
43_V102_K0.9100.26
27_T45_A0.9020.26
6_K52_V0.8900.25
28_T35_H0.8860.25
5_I109_I0.8690.24
31_S105_I0.8600.24
57_A69_L0.8450.23
73_E106_S0.8390.23
29_T93_L0.8380.23
38_E42_T0.8380.23
27_T44_V0.8340.23
4_I63_G0.8310.23
64_P82_T0.8300.23
46_Y51_K0.8290.23
14_E17_A0.8280.23
59_I63_G0.8250.23
29_T33_S0.8160.22
12_S108_Q0.8120.22
77_Y110_S0.8110.22
13_L20_P0.7960.22
41_M64_P0.7940.22
31_S79_E0.7940.22
16_Y20_P0.7930.22
83_E100_G0.7910.21
22_Y109_I0.7900.21
41_M102_K0.7830.21
16_Y87_D0.7730.21
11_A88_E0.7730.21
25_L105_I0.7710.21
44_V78_A0.7680.21
45_A95_A0.7660.21
60_K109_I0.7630.21
48_R93_L0.7520.20
15_R59_I0.7480.20
83_E105_I0.7430.20
27_T104_A0.7420.20
83_E97_H0.7390.20
16_Y112_K0.7390.20
67_V107_L0.7380.20
23_I50_A0.7350.20
19_R76_I0.7330.20
7_E11_A0.7280.19
69_L107_L0.7260.19
39_K43_V0.7250.19
9_V73_E0.7200.19
23_I109_I0.7160.19
95_A103_L0.7150.19
33_S44_V0.7010.19
38_E51_K0.6920.18
41_M83_E0.6730.18
51_K73_E0.6720.18
2_K53_T0.6660.17
2_K8_D0.6590.17
2_K20_P0.6560.17
59_I94_M0.6540.17
11_A15_R0.6530.17
2_K112_K0.6480.17
40_N64_P0.6460.17
60_K93_L0.6430.17
63_G81_L0.6400.17
6_K67_V0.6390.17
18_D39_K0.6350.17
88_E108_Q0.6330.16
38_E47_I0.6310.16
11_A99_P0.6300.16
87_D93_L0.6280.16
27_T40_N0.6280.16
54_Y70_K0.6280.16
2_K84_Y0.6250.16
65_Y79_E0.6180.16
7_E62_N0.6130.16
4_I56_Q0.6090.16
5_I76_I0.6060.16
67_V90_N0.6050.16
44_V98_L0.6020.16
13_L17_A0.6020.16
99_P109_I0.6000.16
77_Y80_G0.5980.16
13_L76_I0.5940.15
43_V56_Q0.5910.15
51_K88_E0.5860.15
34_A39_K0.5850.15
20_P89_E0.5840.15
4_I65_Y0.5680.15
68_G77_Y0.5660.15
8_D65_Y0.5650.15
7_E67_V0.5650.15
7_E14_E0.5580.14
90_N111_E0.5560.14
9_V79_E0.5550.14
56_Q65_Y0.5540.14
97_H103_L0.5530.14
39_K72_E0.5520.14
72_E108_Q0.5490.14
7_E37_N0.5400.14
62_N88_E0.5390.14
59_I65_Y0.5300.14
46_Y91_R0.5300.14
92_L97_H0.5290.14
41_M82_T0.5290.14
11_A52_V0.5280.14
27_T58_K0.5240.14
2_K88_E0.5210.14
50_A79_E0.5200.14
13_L55_H0.5150.13
54_Y71_T0.5130.13
3_A31_S0.5100.13
37_N58_K0.5090.13
34_A51_K0.5050.13
22_Y54_Y0.5050.13
3_A56_Q0.5010.13
87_D92_L0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1njhA 2 0.9138 100 0.049 Contact Map
3k59A 1 0.3534 11.7 0.956 Contact Map
4raaA 1 0.9052 9.2 0.958 Contact Map
4l9bA 3 0.5948 8.7 0.959 Contact Map
2qg3A 2 0.9741 6.5 0.961 Contact Map
1jb7A 1 0.3534 5.9 0.962 Contact Map
3amjB 1 0.25 5.5 0.962 Contact Map
2eecA 1 0.5086 5.5 0.962 Contact Map
4yiiA 1 0.2759 5.4 0.963 Contact Map
2essA 2 0.6897 4.7 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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