GREMLIN Database
YOJM - Superoxide dismutase-like protein YojM
UniProt: O31851 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 196 (151)
Sequences: 1147 (866)
Seq/√Len: 70.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
58_I72_I3.1621.00
131_G135_K2.9631.00
174_T177_S2.8751.00
91_G188_A2.7701.00
167_E182_A2.5751.00
73_S137_D2.4701.00
78_R184_I2.4131.00
155_I161_S2.4121.00
60_I163_F2.3491.00
58_I163_F2.2781.00
72_I138_V2.2391.00
61_K71_H2.1571.00
67_G141_N2.1551.00
45_V187_G2.0881.00
69_D139_I2.0711.00
125_L142_A2.0691.00
80_G130_V1.8541.00
130_V136_V1.8431.00
81_A129_E1.8391.00
101_A162_A1.8391.00
47_L74_A1.8381.00
93_C186_C1.7601.00
87_I189_L1.7551.00
81_A169_A1.7061.00
47_L185_V1.6871.00
171_D178_G1.6160.99
84_G180_S1.5580.99
87_I145_T1.5480.99
105_F154_N1.5450.99
77_L136_V1.5400.99
173_L176_P1.5390.99
86_H104_P1.5270.99
72_I85_F1.5160.99
125_L145_T1.5000.99
49_N55_V1.5000.99
83_L130_V1.4890.99
174_T180_S1.3890.98
112_H121_H1.3830.98
94_V100_S1.3780.98
172_Y175_N1.3760.98
58_I70_I1.3720.98
60_I189_L1.3670.98
177_S182_A1.3450.98
89_E103_G1.3360.98
69_D141_N1.3230.97
80_G83_L1.3200.97
178_G181_G1.3150.97
68_L146_S1.3010.97
68_L145_T1.2930.97
110_K119_G1.2800.97
172_Y176_P1.2800.97
120_H142_A1.2750.97
72_I139_I1.2660.97
170_D178_G1.2420.96
105_F122_A1.2330.96
171_D174_T1.2160.96
57_F73_S1.1940.95
72_I136_V1.1750.95
92_S100_S1.1660.95
107_P121_H1.1630.95
107_P122_A1.1540.94
56_G74_A1.1500.94
95_R99_E1.1440.94
121_H181_G1.1350.94
106_N110_K1.1300.94
68_L147_L1.1090.93
127_N171_D1.1080.93
84_G128_L1.1000.93
104_P166_H1.0970.93
90_K162_A1.0920.93
77_L165_I1.0880.92
86_H166_H1.0870.92
74_A136_V1.0780.92
43_H187_G1.0600.91
45_V91_G1.0590.91
130_V133_D1.0580.91
98_F161_S1.0510.91
168_Q179_N1.0460.91
85_F128_L1.0250.90
74_A165_I0.9990.89
60_I155_I0.9850.88
55_V76_S0.9820.88
43_H91_G0.9710.87
111_E119_G0.9500.86
70_I140_M0.9310.85
63_S69_D0.9290.85
46_Q54_A0.9270.85
114_F172_Y0.9220.85
91_G162_A0.9170.84
79_P130_V0.9140.84
127_N174_T0.9110.84
171_D180_S0.9030.83
147_L154_N0.8990.83
85_F136_V0.8970.83
130_V135_K0.8940.83
43_H47_L0.8870.82
172_Y177_S0.8830.82
78_R83_L0.8820.82
49_N53_K0.8770.81
111_E175_N0.8680.81
121_H170_D0.8660.81
113_G117_P0.8610.80
128_L136_V0.8570.80
156_L161_S0.8560.80
62_E68_L0.8550.80
177_S180_S0.8540.80
93_C176_P0.8530.80
60_I70_I0.8500.79
62_E66_E0.8500.79
121_H177_S0.8400.79
42_G59_E0.8340.78
65_D141_N0.8330.78
106_N122_A0.8250.77
71_H139_I0.8240.77
47_L52_G0.8200.77
105_F161_S0.8120.76
120_H144_D0.8110.76
106_N112_H0.8090.76
104_P181_G0.8050.76
174_T178_G0.8020.75
108_L153_L0.7960.75
90_K161_S0.7920.74
98_F164_I0.7880.74
142_A145_T0.7850.74
103_G166_H0.7850.74
71_H75_N0.7840.74
113_G116_N0.7830.74
126_P172_Y0.7830.74
68_L189_L0.7830.74
175_N189_L0.7770.73
170_D181_G0.7690.72
75_N135_K0.7640.72
47_L187_G0.7390.69
106_N121_H0.7360.69
149_K154_N0.7350.69
148_K154_N0.7330.69
75_N132_A0.7300.68
93_C98_F0.7280.68
163_F189_L0.7230.68
146_S149_K0.7220.67
154_N161_S0.7050.66
97_D100_S0.6980.65
166_H183_R0.6940.64
104_P121_H0.6840.63
62_E147_L0.6780.63
164_I171_D0.6740.62
43_H49_N0.6730.62
106_N109_N0.6700.62
78_R129_E0.6690.62
84_G125_L0.6680.61
93_C101_A0.6660.61
62_E67_G0.6650.61
87_I142_A0.6630.61
98_F119_G0.6610.61
125_L128_L0.6600.60
79_P132_A0.6590.60
92_S98_F0.6560.60
79_P134_G0.6540.60
63_S67_G0.6530.60
164_I177_S0.6490.59
98_F175_N0.6480.59
34_K37_E0.6470.59
112_H178_G0.6400.58
63_S141_N0.6360.58
98_F186_C0.6340.57
168_Q184_I0.6310.57
112_H171_D0.6300.57
60_I68_L0.6270.57
87_I105_F0.6270.57
85_F165_I0.6260.56
142_A174_T0.6260.56
95_R98_F0.6250.56
85_F145_T0.6090.54
113_G171_D0.6090.54
111_E118_M0.6050.54
53_K132_A0.6040.54
86_H183_R0.6000.53
171_D177_S0.5990.53
113_G120_H0.5930.52
118_M152_K0.5910.52
63_S117_P0.5900.52
108_L167_E0.5890.52
105_F145_T0.5880.52
112_H127_N0.5840.51
93_C172_Y0.5840.51
33_K36_V0.5790.51
121_H178_G0.5770.51
88_Y166_H0.5760.50
47_L58_I0.5750.50
35_V73_S0.5740.50
53_K117_P0.5740.50
43_H190_L0.5730.50
164_I174_T0.5700.50
60_I87_I0.5690.50
45_V142_A0.5650.49
163_F187_G0.5620.49
44_H50_R0.5590.48
45_V49_N0.5590.48
71_H137_D0.5580.48
88_Y104_P0.5560.48
169_A174_T0.5530.48
137_D167_E0.5490.47
48_V54_A0.5430.46
81_A115_N0.5420.46
98_F176_P0.5420.46
80_G129_E0.5420.46
34_K38_T0.5390.46
175_N180_S0.5360.46
56_G62_E0.5320.45
171_D181_G0.5310.45
147_L160_G0.5290.45
67_G143_P0.5290.45
43_H74_A0.5280.45
100_S164_I0.5240.44
156_L160_G0.5230.44
66_E145_T0.5230.44
112_H181_G0.5230.44
56_G190_L0.5160.43
51_E184_I0.5140.43
93_C162_A0.5100.42
113_G119_G0.5100.42
77_L184_I0.5080.42
49_N98_F0.5070.42
105_F153_L0.5010.41
99_E164_I0.5010.41
33_K44_H0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xtmB 2 0.7806 100 0.231 Contact Map
1to4A 2 0.7602 100 0.278 Contact Map
3f7lA 2 0.7398 100 0.278 Contact Map
2q2lA 1 0.7449 100 0.279 Contact Map
3pu7A 2 0.7551 100 0.28 Contact Map
3ce1A 2 0.7296 100 0.281 Contact Map
1xsoA 2 0.7347 100 0.281 Contact Map
1f1gA 3 0.7398 100 0.282 Contact Map
2e47A 2 0.7602 100 0.282 Contact Map
3l9yA 2 0.7449 100 0.285 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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