GREMLIN Database
YOJN - Uncharacterized protein YojN
UniProt: O31850 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 304 (239)
Sequences: 14616 (7434)
Seq/√Len: 480.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
213_K216_L3.1571.00
37_E100_V2.8991.00
34_I37_E2.8651.00
147_A150_E2.7091.00
36_P41_L2.6851.00
219_Q222_M2.6161.00
29_Y32_Q2.4571.00
219_Q223_S2.3481.00
278_I282_I2.3191.00
28_S32_Q2.3171.00
103_D106_A2.2681.00
165_M171_G2.1661.00
131_K135_E2.1121.00
256_A259_I2.1041.00
134_K163_K2.0081.00
94_H97_N2.0071.00
240_S243_L1.9911.00
140_Y185_A1.9891.00
131_K134_K1.9401.00
44_T47_Y1.9181.00
214_G218_K1.9091.00
93_M140_Y1.8691.00
38_F41_L1.8681.00
130_T174_I1.8261.00
277_A280_R1.7971.00
218_K222_M1.7871.00
201_K206_I1.7611.00
82_A183_I1.7611.00
69_L144_I1.7601.00
279_E282_I1.7481.00
41_L44_T1.7401.00
258_S261_A1.7301.00
278_I281_G1.7281.00
132_A139_L1.6911.00
241_S245_V1.6841.00
277_A282_I1.6761.00
265_T268_L1.6741.00
261_A265_T1.6701.00
263_I267_D1.6661.00
276_R279_E1.6631.00
279_E283_V1.6541.00
40_S43_G1.6491.00
218_K234_D1.6431.00
37_E40_S1.6161.00
276_R282_I1.6121.00
31_E34_I1.5721.00
33_P37_E1.5631.00
144_I184_A1.5231.00
39_Q43_G1.5071.00
280_R283_V1.4921.00
92_P98_C1.4541.00
163_K173_V1.4481.00
38_F42_I1.4461.00
242_D245_V1.4431.00
30_K128_P1.4361.00
71_K206_I1.4221.00
126_S129_V1.4211.00
259_I265_T1.4151.00
269_A273_P1.4121.00
107_L129_V1.4011.00
61_A68_V1.4001.00
260_R264_D1.3981.00
184_A204_F1.3721.00
79_T142_D1.3651.00
86_S93_M1.3491.00
143_E187_N1.3401.00
218_K245_V1.3371.00
276_R280_R1.3301.00
31_E37_E1.3221.00
30_K132_A1.3151.00
93_M98_C1.3081.00
253_S259_I1.3061.00
278_I283_V1.2931.00
233_I236_F1.2851.00
199_A203_R1.2821.00
194_V197_N1.2721.00
38_F43_G1.2671.00
246_Q252_V1.2671.00
236_F240_S1.2591.00
153_P156_N1.2491.00
214_G241_S1.2331.00
29_Y132_A1.2281.00
277_A281_G1.2281.00
131_K136_G1.2271.00
48_E51_D1.2241.00
86_S138_F1.2191.00
216_L219_Q1.2151.00
82_A140_Y1.2131.00
51_D54_I1.2131.00
34_I38_F1.2101.00
236_F239_L1.2091.00
270_A273_P1.2011.00
262_L266_C1.1961.00
62_L65_G1.1951.00
33_P36_P1.1701.00
29_Y33_P1.1681.00
173_V176_A1.1661.00
242_D246_Q1.1571.00
102_L110_Y1.1571.00
49_A52_E1.1451.00
105_E154_I1.1451.00
57_D61_A1.1331.00
215_E218_K1.1231.00
259_I272_I1.1231.00
139_L182_V1.1181.00
70_L209_V1.1141.00
241_S244_I1.1121.00
141_I182_V1.1091.00
39_Q42_I1.1061.00
261_A264_D1.0981.00
126_S134_K1.0931.00
30_K33_P1.0871.00
214_G217_L1.0821.00
59_I63_A1.0801.00
36_P39_Q1.0781.00
128_P131_K1.0781.00
198_E201_K1.0711.00
190_Y193_T1.0691.00
267_D270_A1.0681.00
272_I275_R1.0551.00
28_S31_E1.0501.00
222_M244_I1.0481.00
277_A283_V1.0461.00
243_L247_A1.0221.00
127_G130_T1.0221.00
265_T272_I1.0151.00
276_R281_G1.0091.00
266_C272_I1.0041.00
270_A274_P0.9991.00
147_A155_L0.9971.00
37_E43_G0.9921.00
150_E153_P0.9901.00
30_K34_I0.9831.00
166_T171_G0.9831.00
235_R240_S0.9811.00
132_A136_G0.9801.00
224_Q227_L0.9781.00
138_F183_I0.9761.00
30_K35_S0.9711.00
35_S40_S0.9691.00
125_V131_K0.9681.00
54_I209_V0.9621.00
233_I240_S0.9611.00
95_S98_C0.9591.00
41_L46_G0.9571.00
81_L209_V0.9511.00
130_T158_V0.9511.00
71_K186_I0.9431.00
240_S244_I0.9381.00
69_L204_F0.9311.00
48_E55_L0.9311.00
222_M241_S0.9301.00
257_A262_L0.9281.00
61_A207_I0.9261.00
88_Y91_K0.9231.00
61_A66_K0.9221.00
58_A65_G0.9211.00
31_E35_S0.9111.00
276_R283_V0.9091.00
37_E42_I0.9011.00
84_T87_S0.9011.00
30_K36_P0.9001.00
253_S260_R0.8971.00
104_A107_L0.8921.00
188_E195_P0.8921.00
30_K41_L0.8921.00
145_N187_N0.8851.00
33_P40_S0.8841.00
56_F59_I0.8821.00
189_G195_P0.8731.00
50_E54_I0.8691.00
29_Y34_I0.8671.00
37_E41_L0.8661.00
52_E56_F0.8601.00
257_A261_A0.8551.00
93_M97_N0.8541.00
232_L236_F0.8521.00
104_A108_V0.8521.00
105_E109_G0.8511.00
133_M136_G0.8471.00
132_A135_E0.8441.00
71_K208_D0.8441.00
266_C273_P0.8421.00
50_E53_A0.8411.00
262_L265_T0.8351.00
69_L201_K0.8341.00
239_L243_L0.8341.00
126_S131_K0.8331.00
35_S38_F0.8291.00
50_E55_L0.8291.00
172_E176_A0.8281.00
28_S36_P0.8281.00
34_I41_L0.8281.00
32_Q37_E0.8271.00
49_A53_A0.8221.00
29_Y36_P0.8211.00
252_V255_E0.8201.00
54_I57_D0.8181.00
166_T173_V0.8151.00
231_K235_R0.8131.00
244_I247_A0.8121.00
32_Q35_S0.8101.00
257_A260_R0.8091.00
258_S273_P0.8091.00
266_C270_A0.8091.00
254_E261_A0.8081.00
36_P43_G0.8071.00
30_K37_E0.8051.00
35_S39_Q0.8041.00
54_I58_A0.8031.00
28_S35_S0.8021.00
260_R263_I0.8011.00
258_S265_T0.7961.00
108_V112_T0.7881.00
255_E258_S0.7851.00
264_D268_L0.7841.00
31_E43_G0.7811.00
252_V256_A0.7791.00
28_S33_P0.7791.00
29_Y35_S0.7731.00
265_T269_A0.7721.00
171_G174_I0.7711.00
93_M96_V0.7681.00
55_L59_I0.7671.00
218_K241_S0.7641.00
94_H137_H0.7601.00
267_D271_Y0.7591.00
54_I62_L0.7581.00
58_A61_A0.7561.00
244_I248_N0.7551.00
57_D60_I0.7541.00
237_I240_S0.7541.00
126_S130_T0.7531.00
36_P40_S0.7521.00
257_A265_T0.7511.00
54_I64_M0.7451.00
139_L180_F0.7411.00
190_Y195_P0.7301.00
48_E52_E0.7291.00
64_M67_N0.7281.00
233_I237_I0.7201.00
256_A260_R0.7131.00
148_K151_T0.7101.00
107_L111_K0.7091.00
230_E233_I0.7041.00
98_C102_L0.7001.00
35_S41_L0.6981.00
54_I61_A0.6981.00
39_Q45_S0.6981.00
259_I263_I0.6931.00
35_S42_I0.6901.00
240_S247_A0.6851.00
84_T88_Y0.6841.00
51_D58_A0.6811.00
94_H98_C0.6801.00
31_E36_P0.6801.00
128_P132_A0.6751.00
160_D203_R0.6751.00
57_D64_M0.6701.00
108_V111_K0.6681.00
188_E208_D0.6621.00
230_E241_S0.6621.00
74_T193_T0.6611.00
255_E259_I0.6601.00
28_S37_E0.6601.00
51_D55_L0.6591.00
258_S264_D0.6541.00
144_I194_V0.6531.00
253_S263_I0.6481.00
33_P39_Q0.6481.00
268_L271_Y0.6471.00
28_S41_L0.6461.00
37_E44_T0.6441.00
171_G176_A0.6441.00
236_F244_I0.6441.00
254_E258_S0.6441.00
58_A68_V0.6431.00
217_L232_L0.6361.00
62_L67_N0.6351.00
61_A64_M0.6351.00
58_A85_L0.6341.00
32_Q36_P0.6311.00
31_E38_F0.6301.00
237_I244_I0.6200.99
35_S43_G0.6200.99
158_V182_V0.6130.99
58_A207_I0.6130.99
69_L184_A0.6120.99
269_A272_I0.6040.99
34_I39_Q0.5990.99
147_A151_T0.5960.99
189_G193_T0.5920.99
237_I241_S0.5880.99
230_E267_D0.5860.99
94_H139_L0.5850.99
92_P96_V0.5850.99
266_C269_A0.5820.99
98_C141_I0.5820.99
133_M180_F0.5780.99
214_G245_V0.5770.99
229_D267_D0.5730.99
58_A70_L0.5730.99
196_L200_L0.5720.99
257_A268_L0.5720.99
63_A95_S0.5710.99
212_I220_V0.5710.99
238_T241_S0.5690.99
31_E39_Q0.5690.99
271_Y275_R0.5660.99
56_F60_I0.5650.99
51_D62_L0.5650.99
241_S247_A0.5640.99
33_P41_L0.5620.99
236_F243_L0.5610.99
226_A239_L0.5550.99
38_F46_G0.5550.99
61_A65_G0.5540.99
80_K83_E0.5490.99
189_G192_G0.5470.99
102_L105_E0.5460.99
261_A268_L0.5450.99
258_S269_A0.5430.99
74_T212_I0.5420.99
172_E175_R0.5410.99
253_S257_A0.5380.99
45_S87_S0.5380.99
42_I45_S0.5370.99
214_G238_T0.5350.98
254_E257_A0.5320.98
145_N186_I0.5310.98
258_S266_C0.5300.98
91_K98_C0.5290.98
38_F45_S0.5290.98
54_I66_K0.5280.98
153_P197_N0.5270.98
160_D180_F0.5260.98
32_Q40_S0.5250.98
251_Q255_E0.5230.98
246_Q269_A0.5210.98
264_D267_D0.5200.98
39_Q46_G0.5190.98
130_T134_K0.5190.98
240_S246_Q0.5190.98
260_R265_T0.5180.98
59_I88_Y0.5180.98
253_S258_S0.5180.98
90_H97_N0.5170.98
188_E193_T0.5170.98
78_K142_D0.5140.98
240_S282_I0.5130.98
184_A200_L0.5090.98
96_V141_I0.5070.98
125_V128_P0.5060.98
212_I217_L0.5060.98
97_N100_V0.5040.98
54_I67_N0.5020.98
222_M225_S0.5000.98
55_L58_A0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rh7A 1 0.9737 100 0.404 Contact Map
4akgA 2 0.9309 100 0.437 Contact Map
3vkgA 2 0.9737 100 0.447 Contact Map
2r44A 1 0.9013 99.9 0.586 Contact Map
1r6bX 1 0.9309 99.9 0.606 Contact Map
4r7yA 3 0.9145 99.8 0.625 Contact Map
3ja87 1 0.9079 99.8 0.63 Contact Map
3pxiA 3 0.8586 99.8 0.633 Contact Map
3ja83 1 0.9211 99.8 0.635 Contact Map
1ofhA 3 0.8586 99.8 0.636 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0091 seconds.