YOZB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YOZB - Uncharacterized membrane protein YozB

UniProt:	O31845	Sequences: MNQTENKPKNYTGIVLTLTVLINGLIAVLFFMPKLDQFSHANIHILPMLNAIFNSFTFIFLLAALIMIKQKNIKAHKRFILAAFTTTLLFLICYVTYHSIAENTLYGGEGIMRPIYFFILITHICLSAIIVPLALFTLIRGFSMQVERHKKIARWTMPLWLYVSLTGVIVYLMISPYY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	178 (161)
Sequences:	632 (377)
Seq/√Len:	29.7

BACSU - YOZB
HALSA - Q9HPS5 Q9HRJ3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
106_Y	112_M	5.091	1.00
137_T	153_A	4.718	1.00
141_G	146_V	4.089	1.00
67_M	79_F	3.694	1.00
137_T	156_T	3.154	1.00
64_A	80_I	2.985	1.00
67_M	75_A	2.952	1.00
68_I	73_I	2.921	1.00
74_K	78_R	2.813	1.00
60_F	79_F	2.524	0.99
81_L	142_F	2.500	0.99
113_R	117_F	2.195	0.98
21_L	25_L	2.141	0.98
60_F	86_T	2.105	0.98
25_L	28_V	2.088	0.98
18_L	22_I	2.086	0.98
131_V	134_A	1.971	0.97
72_N	75_A	1.935	0.96
62_L	161_L	1.730	0.93
121_I	125_C	1.668	0.92
50_N	164_S	1.649	0.91
77_K	81_L	1.610	0.90
111_I	115_I	1.576	0.89
158_P	162_Y	1.566	0.89
114_P	118_F	1.562	0.89
133_L	155_W	1.551	0.88
65_L	71_K	1.529	0.88
17_T	21_L	1.528	0.88
130_I	159_L	1.499	0.87
58_F	165_L	1.485	0.86
19_T	24_G	1.432	0.84
148_R	151_K	1.415	0.83
53_F	86_T	1.413	0.83
55_S	168_V	1.405	0.83
22_I	26_I	1.401	0.83
43_I	96_T	1.397	0.83
140_R	153_A	1.394	0.82
153_A	156_T	1.394	0.82
49_L	77_K	1.391	0.82
49_L	93_C	1.384	0.82
118_F	122_T	1.374	0.81
21_L	148_R	1.355	0.81
111_I	114_P	1.351	0.80
137_T	140_R	1.344	0.80
125_C	128_A	1.315	0.78
65_L	69_K	1.284	0.77
13_G	17_T	1.266	0.76
140_R	152_I	1.266	0.76
16_L	20_V	1.245	0.75
47_P	170_V	1.245	0.75
84_F	138_L	1.240	0.74
50_N	93_C	1.220	0.73
172_L	177_Y	1.218	0.73
88_L	92_I	1.191	0.71
33_P	127_S	1.167	0.70
62_L	66_I	1.160	0.69
158_P	163_V	1.146	0.68
135_L	139_I	1.135	0.67
73_I	146_V	1.133	0.67
40_H	106_Y	1.127	0.67
88_L	155_W	1.122	0.66
54_N	87_T	1.112	0.66
58_F	161_L	1.110	0.66
109_E	112_M	1.108	0.65
33_P	36_D	1.093	0.64
136_F	152_I	1.065	0.62
95_V	134_A	1.064	0.62
84_F	134_A	1.062	0.62
141_G	144_M	1.058	0.62
104_T	174_I	1.050	0.61
81_L	85_T	1.046	0.61
87_T	157_M	1.031	0.60
75_A	79_F	1.031	0.60
133_L	159_L	1.030	0.60
58_F	164_S	1.016	0.59
56_F	60_F	1.015	0.59
111_I	122_T	1.012	0.58
14_I	18_L	1.009	0.58
112_M	115_I	1.003	0.58
19_T	132_P	1.002	0.58
142_F	152_I	1.001	0.57
15_V	19_T	0.998	0.57
142_F	145_Q	0.983	0.56
87_T	164_S	0.982	0.56
64_A	84_F	0.981	0.56
117_F	121_I	0.964	0.55
54_N	61_L	0.960	0.54
112_M	117_F	0.959	0.54
145_Q	148_R	0.955	0.54
105_L	114_P	0.937	0.52
152_I	156_T	0.931	0.52
122_T	162_Y	0.924	0.51
73_I	156_T	0.922	0.51
80_I	141_G	0.903	0.50
140_R	145_Q	0.898	0.49
27_A	30_F	0.894	0.49
106_Y	136_F	0.889	0.49
136_F	141_G	0.885	0.48
82_A	86_T	0.881	0.48
130_I	134_A	0.880	0.48
60_F	83_A	0.878	0.48
65_L	157_M	0.873	0.47
111_I	129_I	0.870	0.47
36_D	53_F	0.858	0.46
23_N	27_A	0.850	0.46
78_R	81_L	0.842	0.45
20_V	23_N	0.842	0.45
68_I	85_T	0.833	0.44
48_M	52_I	0.830	0.44
130_I	153_A	0.824	0.44
25_L	95_V	0.823	0.44
24_G	28_V	0.816	0.43
21_L	28_V	0.814	0.43
142_F	147_E	0.807	0.42
71_K	138_L	0.806	0.42
103_N	124_I	0.804	0.42
40_H	43_I	0.800	0.42
52_I	56_F	0.792	0.41
157_M	161_L	0.781	0.40
59_I	114_P	0.768	0.39
63_A	85_T	0.767	0.39
105_L	113_R	0.757	0.38
60_F	82_A	0.754	0.38
41_A	127_S	0.751	0.38
27_A	32_M	0.750	0.38
69_K	77_K	0.749	0.38
52_I	72_N	0.748	0.38
89_L	169_I	0.747	0.38
81_L	138_L	0.743	0.37
140_R	148_R	0.742	0.37
52_I	83_A	0.737	0.37
53_F	93_C	0.730	0.36
20_V	32_M	0.729	0.36
162_Y	168_V	0.728	0.36
48_M	171_Y	0.726	0.36
104_T	175_S	0.722	0.36
85_T	165_L	0.720	0.36
50_N	127_S	0.720	0.36
108_G	112_M	0.718	0.36
61_L	168_V	0.717	0.36
97_Y	174_I	0.712	0.35
13_G	32_M	0.709	0.35
41_A	45_I	0.707	0.35
110_G	115_I	0.705	0.35
98_H	173_M	0.704	0.35
13_G	16_L	0.698	0.34
22_I	27_A	0.697	0.34
22_I	131_V	0.697	0.34
56_F	157_M	0.696	0.34
136_F	139_I	0.696	0.34
97_Y	100_I	0.694	0.34
95_V	173_M	0.694	0.34
104_T	113_R	0.694	0.34
109_E	117_F	0.691	0.34
82_A	110_G	0.686	0.33
18_L	21_L	0.686	0.33
73_I	84_F	0.683	0.33
21_L	95_V	0.683	0.33
128_A	148_R	0.683	0.33
118_F	150_K	0.679	0.33
153_A	157_M	0.677	0.33
132_P	159_L	0.677	0.33
69_K	73_I	0.671	0.32
64_A	82_A	0.671	0.32
108_G	111_I	0.670	0.32
49_L	62_L	0.667	0.32
23_N	87_T	0.667	0.32
86_T	164_S	0.658	0.31
93_C	96_T	0.657	0.31
13_G	41_A	0.655	0.31
80_I	144_M	0.654	0.31
46_L	124_I	0.653	0.31
70_Q	150_K	0.651	0.31
54_N	164_S	0.649	0.31
49_L	56_F	0.648	0.31
23_N	57_T	0.639	0.30
79_F	82_A	0.637	0.30
69_K	138_L	0.635	0.30
133_L	143_S	0.634	0.30
51_A	54_N	0.634	0.30
17_T	59_I	0.634	0.30
45_I	81_L	0.623	0.29
131_V	135_L	0.618	0.29
49_L	104_T	0.617	0.29
78_R	82_A	0.614	0.28
83_A	161_L	0.612	0.28
128_A	143_S	0.605	0.28
152_I	171_Y	0.602	0.28
70_Q	75_A	0.601	0.28
119_I	133_L	0.600	0.28
18_L	142_F	0.598	0.27
96_T	100_I	0.598	0.27
56_F	63_A	0.597	0.27
153_A	163_V	0.597	0.27
30_F	139_I	0.596	0.27
88_L	150_K	0.591	0.27
57_T	131_V	0.591	0.27
46_L	61_L	0.588	0.27
130_I	133_L	0.586	0.27
29_L	47_P	0.585	0.27
19_T	25_L	0.575	0.26
57_T	102_E	0.571	0.26
81_L	139_I	0.565	0.25
65_L	122_T	0.562	0.25
154_R	157_M	0.561	0.25
23_N	134_A	0.558	0.25
103_N	117_F	0.557	0.25
114_P	122_T	0.551	0.25
46_L	97_Y	0.548	0.24
73_I	138_L	0.547	0.24
53_F	87_T	0.547	0.24
36_D	42_N	0.541	0.24
20_V	113_R	0.540	0.24
122_T	163_V	0.538	0.24
27_A	99_S	0.538	0.24
77_K	100_I	0.536	0.24
128_A	136_F	0.532	0.24
16_L	136_F	0.529	0.23
107_G	178_Y	0.529	0.23
48_M	55_S	0.525	0.23
106_Y	114_P	0.524	0.23
72_N	147_E	0.522	0.23
64_A	67_M	0.520	0.23
14_I	25_L	0.518	0.23
133_L	137_T	0.518	0.23
136_F	140_R	0.517	0.23
28_V	121_I	0.517	0.23
160_W	167_G	0.516	0.23
89_L	93_C	0.513	0.22
13_G	33_P	0.512	0.22
28_V	36_D	0.512	0.22
28_V	31_F	0.512	0.22
150_K	159_L	0.511	0.22
64_A	79_F	0.510	0.22
122_T	153_A	0.507	0.22
21_L	70_Q	0.506	0.22
65_L	73_I	0.505	0.22
23_N	30_F	0.502	0.22
31_F	53_F	0.501	0.22
15_V	23_N	0.501	0.22
20_V	143_S	0.501	0.22
19_T	23_N	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1fftC	1	0.9663	97.1	0.883	Contact Map
2yevA	1	0.9775	95.7	0.899	Contact Map
1v54C	1	0.9831	95.3	0.901	Contact Map
1qleC	1	0.9831	92.9	0.912	Contact Map
1m56C	2	0.9831	92.3	0.913	Contact Map
4o6yA	2	0.8764	52.3	0.941	Contact Map
3j1zP	8	0.927	30.4	0.949	Contact Map
4n6hA	1	0.8539	22.5	0.952	Contact Map
3dh4A	3	0.8708	20.9	0.952	Contact Map
2lnlA	1	0.8427	20.2	0.953	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0066 seconds.