GREMLIN Database
YOZK - DNA repair protein homolog YozK
UniProt: O31841 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 115 (107)
Sequences: 793 (398)
Seq/√Len: 38.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
28_A88_L4.7381.00
92_V95_E4.5351.00
105_P108_C3.9541.00
26_A36_C3.3611.00
87_K91_R3.2041.00
28_A92_V3.0931.00
47_Q74_P3.0631.00
29_M82_V2.7501.00
104_V109_V2.3021.00
90_I114_I1.8770.98
95_E98_K1.8480.98
94_T98_K1.7210.97
62_F68_S1.6860.96
54_A64_I1.6300.95
28_A85_Q1.5880.95
64_I68_S1.5280.93
88_L92_V1.4390.91
21_Y55_S1.4300.91
25_S85_Q1.4070.90
101_Y106_E1.3920.90
88_L91_R1.3730.89
42_G50_V1.3550.88
84_P90_I1.3460.88
24_V28_A1.3310.88
98_K101_Y1.3270.87
57_A61_D1.3170.87
73_I76_D1.2650.85
35_T57_A1.2580.84
28_A91_R1.2540.84
29_M91_R1.2420.84
31_L80_Y1.2110.82
54_A58_L1.2020.82
71_F87_K1.1870.81
43_N81_I1.1860.81
25_S89_F1.1590.79
96_I99_L1.1580.79
38_L82_V1.1460.78
37_Y57_A1.1420.78
103_F110_H1.1320.77
32_N35_T1.1040.76
66_T74_P1.0930.75
97_T109_V1.0900.75
24_V88_L1.0890.75
74_P79_I1.0760.74
18_K34_L1.0740.74
41_V50_V1.0710.73
54_A66_T1.0290.70
15_V100_F1.0260.70
93_S97_T1.0190.70
21_Y90_I1.0190.70
11_N90_I1.0150.69
44_T83_N1.0110.69
13_L90_I1.0020.68
85_Q88_L0.9960.68
12_I37_Y0.9900.67
61_D78_R0.9890.67
65_K73_I0.9830.67
70_L81_I0.9750.66
54_A72_E0.9630.65
41_V70_L0.9570.65
39_A73_I0.9390.63
58_L79_I0.9220.62
37_Y62_F0.9060.60
42_G93_S0.9000.60
91_R95_E0.8890.59
33_P38_L0.8690.57
26_A38_L0.8550.56
43_N46_R0.8350.54
54_A68_S0.8310.54
51_V79_I0.8220.53
64_I77_P0.8190.53
46_R49_S0.8150.52
21_Y85_Q0.8100.52
42_G49_S0.8040.51
11_N27_V0.8030.51
51_V77_P0.7890.50
29_M83_N0.7860.50
17_M100_F0.7850.50
70_L73_I0.7840.50
68_S74_P0.7700.48
51_V73_I0.7680.48
41_V49_S0.7620.48
72_E81_I0.7590.47
11_N24_V0.7540.47
112_Y115_D0.7540.47
51_V54_A0.7460.46
62_F78_R0.7400.46
29_M38_L0.7390.46
37_Y77_P0.7390.46
28_A95_E0.7230.44
21_Y49_S0.7200.44
71_F85_Q0.7120.43
100_F111_T0.7060.43
46_R66_T0.6940.42
13_L64_I0.6920.41
14_C71_F0.6850.41
13_L94_T0.6810.40
20_F104_V0.6790.40
37_Y78_R0.6750.40
88_L100_F0.6740.40
54_A65_K0.6730.40
63_G89_F0.6710.40
10_E84_P0.6710.40
27_V99_L0.6700.39
58_L66_T0.6660.39
42_G45_D0.6650.39
10_E13_L0.6650.39
41_V45_D0.6590.39
11_N43_N0.6580.38
104_V108_C0.6450.37
91_R96_I0.6450.37
37_Y61_D0.6380.37
99_L106_E0.6380.37
43_N47_Q0.6310.36
91_R98_K0.6300.36
15_V20_F0.6250.36
62_F76_D0.6210.35
58_L67_G0.6180.35
49_S93_S0.6120.35
14_C73_I0.6080.34
48_G71_F0.6070.34
39_A54_A0.6070.34
50_V67_G0.6060.34
78_R102_R0.6040.34
11_N14_C0.6040.34
51_V68_S0.6030.34
69_R72_E0.6030.34
42_G97_T0.5950.33
48_G70_L0.5880.33
58_L106_E0.5830.32
39_A81_I0.5780.32
26_A62_F0.5760.32
24_V91_R0.5760.32
44_T70_L0.5750.32
12_I51_V0.5680.31
28_A63_G0.5660.31
101_Y109_V0.5630.31
69_R103_F0.5610.31
96_I103_F0.5600.31
33_P40_V0.5570.30
14_C66_T0.5570.30
21_Y109_V0.5570.30
39_A64_I0.5510.30
33_P69_R0.5440.29
31_L35_T0.5420.29
29_M80_Y0.5400.29
99_L109_V0.5380.29
50_V65_K0.5370.29
14_C48_G0.5350.29
91_R102_R0.5290.28
54_A67_G0.5280.28
25_S82_V0.5230.28
30_G95_E0.5220.28
25_S29_M0.5150.27
9_R114_I0.5150.27
14_C37_Y0.5140.27
36_C80_Y0.5110.27
8_P75_E0.5070.27
20_F24_V0.5060.27
39_A58_L0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2aq4A 1 0.9739 99.9 0.542 Contact Map
3osnA 1 0.8696 99.9 0.545 Contact Map
4f50A 1 0.8609 99.9 0.553 Contact Map
4q45F 1 0.8957 99.9 0.553 Contact Map
4tqrA 1 0.887 99.9 0.565 Contact Map
4dezA 2 0.8609 99.9 0.566 Contact Map
3pzpA 1 0.9217 99.9 0.567 Contact Map
4ecqA 1 0.9391 99.9 0.569 Contact Map
1t94A 1 0.9217 99.9 0.57 Contact Map
3mfiA 1 0.9217 99.9 0.592 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0052 seconds.