YNGI - BACSU - GREMLIN Contacts

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YNGI - Putative acyl-CoA synthetase YngI

UniProt:	O31826	Sequences: MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGKGDHVAIWASNISEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLSGMYHWDDTEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTVLHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVMKGYYKDKDATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEFLYQHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVIFTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	549 (485)
Sequences:	71184 (51199)
Seq/√Len:	2324.8

ECOLI - ACSA FADK PRPE LCFA ENTF AAS CAIC ENTE MENE PAAK
BACSU - YNGI DHBE ACSA LCFA SRFAC LCFB PPSE YDAB YTCI MENE DLTA PPSC YHFT PPSB DHBF PKSJ PPSD SRFAA SRFAB
HALSA - Q9HRY8 Q9HQU8 Q9HSM3 Q9HNK0 Q9HQ43 Q9HQN8
SULSO - Q97UX8 Q97VT6 Q97U22 Q97UW7 Q97YK9 Q97WQ9 Q97VU7 Q97WQ0 Q97UF6 Q97WK0 Q97XW4 Q97V27 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
192_V	209_M	3.982	1.00
391_L	425_A	3.338	1.00
462_H	502_Y	3.068	1.00
104_Q	197_Y	3.031	1.00
371_E	394_R	2.999	1.00
56_I	84_A	2.894	1.00
405_D	408_A	2.887	1.00
45_R	81_K	2.875	1.00
60_D	108_A	2.763	1.00
211_T	400_K	2.761	1.00
63_A	107_A	2.710	1.00
41_D	81_K	2.646	1.00
426_V	434_R	2.623	1.00
61_H	87_V	2.488	1.00
27_V	259_A	2.474	1.00
390_E	420_F	2.437	1.00
444_I	449_N	2.399	1.00
24_D	34_R	2.392	1.00
106_D	404_K	2.386	1.00
233_R	259_A	2.378	1.00
467_D	524_M	2.362	1.00
376_E	381_Q	2.282	1.00
388_Q	424_L	2.281	1.00
20_Y	23_R	2.280	1.00
459_L	484_A	2.276	1.00
460_Y	468_V	2.253	1.00
375_V	392_C	2.234	1.00
373_K	382_E	2.205	1.00
50_G	54_M	2.200	1.00
14_E	41_D	2.199	1.00
75_V	111_I	2.197	1.00
273_K	277_K	2.159	1.00
104_Q	405_D	2.140	1.00
232_D	308_R	2.089	1.00
16_T	20_Y	2.086	1.00
43_L	74_A	2.075	1.00
100_Y	204_F	2.046	1.00
188_D	191_N	2.039	1.00
28_Y	70_S	2.018	1.00
461_Q	506_K	2.009	1.00
392_C	420_F	1.995	1.00
483_A	517_I	1.986	1.00
362_T	434_R	1.957	1.00
47_T	74_A	1.956	1.00
41_D	45_R	1.936	1.00
58_K	191_N	1.935	1.00
79_T	84_A	1.925	1.00
428_D	434_R	1.925	1.00
408_A	411_K	1.917	1.00
531_Q	534_K	1.907	1.00
406_K	410_R	1.900	1.00
232_D	281_T	1.899	1.00
441_D	532_K	1.886	1.00
428_D	432_Y	1.869	1.00
108_A	149_K	1.869	1.00
22_D	38_A	1.840	1.00
59_G	191_N	1.806	1.00
445_R	450_I	1.793	1.00
99_D	103_K	1.782	1.00
44_C	81_K	1.771	1.00
319_S	323_K	1.764	1.00
427_M	433_C	1.760	1.00
373_K	392_C	1.758	1.00
52_M	82_I	1.750	1.00
454_E	511_K	1.741	1.00
57_G	60_D	1.734	1.00
27_V	34_R	1.712	1.00
426_V	436_T	1.701	1.00
261_I	280_C	1.694	1.00
38_A	42_S	1.672	1.00
534_K	537_E	1.659	1.00
67_S	113_M	1.658	1.00
388_Q	436_T	1.655	1.00
15_Q	19_A	1.651	1.00
211_T	214_N	1.649	1.00
460_Y	467_D	1.647	1.00
374_I	425_A	1.646	1.00
27_V	278_E	1.642	1.00
485_W	535_L	1.642	1.00
73_L	250_V	1.639	1.00
470_V	484_A	1.635	1.00
385_R	427_M	1.634	1.00
456_E	470_V	1.626	1.00
466_L	489_K	1.617	1.00
192_V	400_K	1.612	1.00
80_A	193_I	1.601	1.00
279_K	306_T	1.592	1.00
63_A	89_V	1.585	1.00
45_R	49_K	1.557	1.00
487_K	522_Y	1.556	1.00
54_M	150_T	1.549	1.00
471_V	485_W	1.546	1.00
35_Y	74_A	1.528	1.00
407_D	411_K	1.526	1.00
384_Q	387_M	1.518	1.00
285_G	290_F	1.510	1.00
253_C	258_A	1.507	1.00
105_S	197_Y	1.502	1.00
36_T	39_Q	1.497	1.00
62_V	79_T	1.492	1.00
214_N	344_S	1.492	1.00
347_I	393_T	1.491	1.00
495_S	498_E	1.489	1.00
333_D	351_R	1.484	1.00
323_K	327_E	1.482	1.00
270_T	273_K	1.472	1.00
16_T	19_A	1.468	1.00
502_Y	506_K	1.468	1.00
190_D	213_F	1.462	1.00
24_D	27_V	1.459	1.00
464_A	498_E	1.451	1.00
359_R	430_D	1.445	1.00
425_A	435_I	1.444	1.00
24_D	259_A	1.435	1.00
377_P	439_L	1.435	1.00
197_Y	207_G	1.431	1.00
23_R	231_Q	1.431	1.00
235_C	280_C	1.429	1.00
25_A	40_F	1.426	1.00
195_M	403_Y	1.425	1.00
394_R	418_W	1.416	1.00
340_Q	419_L	1.409	1.00
525_T	531_Q	1.408	1.00
458_F	506_K	1.405	1.00
486_I	516_V	1.404	1.00
232_D	282_V	1.399	1.00
288_T	315_S	1.398	1.00
372_V	393_T	1.396	1.00
14_E	81_K	1.396	1.00
290_F	310_G	1.388	1.00
61_H	85_V	1.386	1.00
486_I	518_F	1.384	1.00
276_E	302_Y	1.384	1.00
28_Y	31_R	1.382	1.00
21_P	38_A	1.380	1.00
209_M	401_G	1.379	1.00
35_Y	70_S	1.378	1.00
488_L	518_F	1.373	1.00
376_E	383_V	1.372	1.00
62_V	84_A	1.370	1.00
47_T	78_A	1.369	1.00
104_Q	404_K	1.367	1.00
223_A	256_V	1.367	1.00
78_A	82_I	1.361	1.00
59_G	400_K	1.361	1.00
474_P	480_E	1.359	1.00
224_E	368_P	1.358	1.00
63_A	102_L	1.339	1.00
229_T	232_D	1.337	1.00
399_M	413_I	1.337	1.00
500_K	516_V	1.334	1.00
102_L	107_A	1.327	1.00
263_V	274_T	1.322	1.00
209_M	403_Y	1.319	1.00
17_A	41_D	1.319	1.00
412_A	419_L	1.316	1.00
348_T	372_V	1.308	1.00
443_L	452_P	1.301	1.00
501_A	505_G	1.300	1.00
61_H	403_Y	1.300	1.00
34_R	278_E	1.299	1.00
233_R	280_C	1.296	1.00
312_M	317_C	1.295	1.00
475_D	481_E	1.284	1.00
233_R	261_I	1.283	1.00
56_I	60_D	1.282	1.00
267_D	270_T	1.280	1.00
85_V	192_V	1.278	1.00
56_I	62_V	1.277	1.00
388_Q	426_V	1.273	1.00
61_H	195_M	1.259	1.00
274_T	278_E	1.256	1.00
87_V	105_S	1.253	1.00
424_L	439_L	1.250	1.00
42_S	46_Q	1.246	1.00
391_L	435_I	1.243	1.00
359_R	432_Y	1.240	1.00
275_V	306_T	1.237	1.00
189_K	213_F	1.235	1.00
77_F	254_V	1.232	1.00
64_I	75_V	1.230	1.00
504_K	512_I	1.227	1.00
114_D	155_G	1.221	1.00
89_V	98_L	1.217	1.00
485_W	536_R	1.205	1.00
365_R	432_Y	1.205	1.00
100_Y	104_Q	1.202	1.00
473_V	483_A	1.197	1.00
283_L	307_L	1.193	1.00
198_T	208_V	1.192	1.00
485_W	519_T	1.192	1.00
383_V	387_M	1.191	1.00
214_N	398_V	1.188	1.00
500_K	504_K	1.186	1.00
483_A	515_Y	1.182	1.00
43_L	46_Q	1.180	1.00
295_H	324_A	1.178	1.00
40_F	77_F	1.172	1.00
467_D	487_K	1.171	1.00
502_Y	505_G	1.162	1.00
484_A	516_V	1.158	1.00
244_F	284_H	1.157	1.00
29_P	264_Q	1.145	1.00
213_F	396_Y	1.143	1.00
41_D	182_E	1.143	1.00
390_E	439_L	1.141	1.00
366_A	372_V	1.137	1.00
441_D	453_R	1.136	1.00
39_Q	42_S	1.134	1.00
453_R	457_E	1.134	1.00
373_K	418_W	1.133	1.00
109_A	150_T	1.131	1.00
195_M	207_G	1.131	1.00
44_C	78_A	1.130	1.00
103_K	204_F	1.128	1.00
187_L	191_N	1.124	1.00
104_Q	204_F	1.121	1.00
66_A	154_I	1.112	1.00
504_K	509_R	1.110	1.00
503_C	512_I	1.109	1.00
95_A	99_D	1.107	1.00
47_T	111_I	1.107	1.00
282_V	309_T	1.103	1.00
14_E	45_R	1.097	1.00
210_L	214_N	1.096	1.00
56_I	109_A	1.096	1.00
209_M	400_K	1.084	1.00
496_P	516_V	1.081	1.00
448_E	510_H	1.080	1.00
481_E	514_R	1.080	1.00
50_G	53_R	1.078	1.00
485_W	539_T	1.076	1.00
519_T	522_Y	1.074	1.00
472_G	480_E	1.072	1.00
350_T	432_Y	1.067	1.00
374_I	383_V	1.066	1.00
496_P	518_F	1.061	1.00
35_Y	43_L	1.060	1.00
72_W	240_F	1.060	1.00
100_Y	197_Y	1.056	1.00
25_A	37_Y	1.056	1.00
458_F	503_C	1.053	1.00
43_L	71_E	1.052	1.00
488_L	494_V	1.050	1.00
481_E	515_Y	1.049	1.00
261_I	274_T	1.046	1.00
97_E	511_K	1.043	1.00
325_V	329_M	1.040	1.00
462_H	499_L	1.040	1.00
27_V	261_I	1.037	1.00
370_T	397_H	1.036	1.00
393_T	421_T	1.032	1.00
23_R	259_A	1.029	1.00
269_V	296_H	1.028	1.00
318_P	321_V	1.026	1.00
48_A	81_K	1.026	1.00
464_A	492_K	1.023	1.00
363_T	435_I	1.022	1.00
65_W	98_L	1.019	1.00
233_R	281_T	1.017	1.00
372_V	391_L	1.017	1.00
442_M	451_Y	1.017	1.00
190_D	211_T	1.014	1.00
24_D	36_T	1.013	1.00
238_V	244_F	1.013	1.00
40_F	74_A	1.012	1.00
522_Y	530_I	1.012	1.00
392_C	418_W	1.011	1.00
414_N	420_F	1.010	1.00
234_M	253_C	1.009	1.00
232_D	258_A	1.009	1.00
60_D	84_A	1.009	1.00
348_T	433_C	1.004	1.00
291_I	321_V	1.001	1.00
443_L	482_A	1.001	1.00
395_G	398_V	1.000	1.00
473_V	515_Y	0.999	1.00
95_A	119_T	0.997	1.00
408_A	412_A	0.995	1.00
261_I	278_E	0.995	1.00
196_Q	341_T	0.990	1.00
446_G	478_F	0.990	1.00
208_V	399_M	0.988	1.00
217_N	369_H	0.986	1.00
294_L	324_A	0.985	1.00
49_K	179_E	0.978	1.00
324_A	328_R	0.978	1.00
456_E	532_K	0.977	1.00
199_S	527_S	0.976	1.00
508_A	511_K	0.974	1.00
469_Q	522_Y	0.973	1.00
424_L	437_G	0.969	1.00
13_L	17_A	0.963	1.00
372_V	433_C	0.963	1.00
350_T	362_T	0.962	1.00
499_L	516_V	0.960	1.00
51_L	79_T	0.958	1.00
533_Y	537_E	0.954	1.00
41_D	44_C	0.952	1.00
49_K	183_R	0.952	1.00
498_E	501_A	0.951	1.00
253_C	260_M	0.950	1.00
519_T	538_K	0.950	1.00
317_C	322_M	0.949	1.00
56_I	82_I	0.949	1.00
217_N	396_Y	0.946	1.00
47_T	75_V	0.945	1.00
35_Y	40_F	0.941	1.00
391_L	433_C	0.934	1.00
376_E	387_M	0.934	1.00
26_V	73_L	0.930	1.00
53_R	178_A	0.928	1.00
90_N	241_F	0.924	1.00
61_H	106_D	0.923	1.00
93_Y	101_L	0.922	1.00
40_F	44_C	0.922	1.00
266_F	289_M	0.920	1.00
458_F	461_Q	0.916	1.00
96_H	506_K	0.915	1.00
113_M	116_Y	0.915	1.00
218_N	345_P	0.912	1.00
461_Q	502_Y	0.909	1.00
497_D	501_A	0.909	1.00
70_S	74_A	0.909	1.00
445_R	472_G	0.907	1.00
96_H	99_D	0.902	1.00
462_H	498_E	0.901	1.00
66_A	69_I	0.897	1.00
534_K	538_K	0.897	1.00
193_I	212_H	0.896	1.00
219_A	255_S	0.896	1.00
52_M	183_R	0.895	1.00
297_P	301_A	0.889	1.00
100_Y	405_D	0.888	1.00
466_L	487_K	0.887	1.00
54_M	109_A	0.883	1.00
292_A	477_K	0.882	1.00
464_A	489_K	0.879	1.00
63_A	110_L	0.879	1.00
235_C	263_V	0.877	1.00
362_T	432_Y	0.875	1.00
474_P	477_K	0.874	1.00
231_Q	281_T	0.869	1.00
49_K	52_M	0.869	1.00
10_G	187_L	0.865	1.00
374_I	433_C	0.864	1.00
210_L	344_S	0.863	1.00
192_V	211_T	0.861	1.00
51_L	111_I	0.857	1.00
284_H	346_V	0.856	1.00
343_A	419_L	0.856	1.00
359_R	428_D	0.855	1.00
100_Y	103_K	0.848	1.00
375_V	382_E	0.847	1.00
52_M	57_G	0.847	1.00
64_I	86_L	0.846	1.00
311_I	337_A	0.845	1.00
320_E	324_A	0.841	1.00
27_V	233_R	0.839	1.00
469_Q	535_L	0.835	1.00
79_T	86_L	0.834	1.00
76_Q	86_L	0.833	1.00
96_H	100_Y	0.832	1.00
13_L	77_F	0.829	1.00
324_A	327_E	0.828	1.00
290_F	325_V	0.828	1.00
76_Q	246_C	0.824	1.00
237_P	289_M	0.818	1.00
485_W	538_K	0.818	1.00
501_A	504_K	0.815	1.00
464_A	488_L	0.815	1.00
26_V	70_S	0.813	1.00
233_R	279_K	0.812	1.00
343_A	398_V	0.811	1.00
291_I	318_P	0.811	1.00
71_E	74_A	0.811	1.00
15_Q	18_D	0.809	1.00
48_A	82_I	0.807	1.00
492_K	495_S	0.805	1.00
498_E	502_Y	0.799	1.00
309_T	335_T	0.798	1.00
243_C	340_Q	0.797	1.00
101_L	207_G	0.796	1.00
23_R	230_S	0.794	1.00
394_R	416_D	0.793	1.00
73_L	262_P	0.790	1.00
413_I	420_F	0.790	1.00
243_C	345_P	0.788	1.00
40_F	73_L	0.788	1.00
12_L	220_A	0.785	1.00
42_S	180_L	0.783	1.00
67_S	115_S	0.782	1.00
371_E	418_W	0.782	1.00
74_A	78_A	0.782	1.00
210_L	399_M	0.780	1.00
12_L	16_T	0.779	1.00
445_R	514_R	0.778	1.00
276_E	303_D	0.774	1.00
372_V	425_A	0.769	1.00
79_T	82_I	0.768	1.00
14_E	18_D	0.767	1.00
380_C	392_C	0.766	1.00
63_A	87_V	0.766	1.00
39_Q	43_L	0.766	1.00
407_D	410_R	0.765	1.00
343_A	393_T	0.765	1.00
459_L	468_V	0.764	1.00
286_V	289_M	0.761	1.00
405_D	409_T	0.760	1.00
31_R	70_S	0.758	1.00
469_Q	530_I	0.757	1.00
114_D	156_N	0.756	1.00
415_H	420_F	0.755	1.00
112_I	153_Y	0.752	1.00
500_K	512_I	0.752	1.00
20_Y	38_A	0.751	1.00
66_A	111_I	0.751	1.00
43_L	70_S	0.748	1.00
46_Q	50_G	0.745	1.00
129_I	132_L	0.743	1.00
24_D	28_Y	0.743	1.00
452_P	470_V	0.742	1.00
106_D	403_Y	0.741	1.00
307_L	310_G	0.740	1.00
302_Y	305_S	0.740	1.00
193_I	215_V	0.739	1.00
10_G	212_H	0.739	1.00
474_P	478_F	0.739	1.00
474_P	479_G	0.738	1.00
486_I	499_L	0.736	1.00
270_T	274_T	0.736	1.00
317_C	334_I	0.735	1.00
386_G	429_E	0.735	1.00
65_W	110_L	0.733	1.00
445_R	482_A	0.733	1.00
269_V	273_K	0.731	1.00
218_N	344_S	0.730	1.00
96_H	204_F	0.730	1.00
281_T	308_R	0.726	1.00
112_I	151_L	0.725	1.00
112_I	116_Y	0.724	1.00
11_R	15_Q	0.723	1.00
310_G	325_V	0.722	1.00
87_V	107_A	0.721	1.00
487_K	521_D	0.721	1.00
290_F	312_M	0.721	1.00
309_T	333_D	0.720	1.00
320_E	323_K	0.720	1.00
496_P	500_K	0.712	1.00
374_I	391_L	0.712	1.00
194_N	210_L	0.711	1.00
75_V	79_T	0.710	1.00
244_F	313_A	0.709	1.00
95_A	131_E	0.709	1.00
228_L	282_V	0.708	1.00
11_R	14_E	0.708	1.00
377_P	390_E	0.708	1.00
114_D	153_Y	0.708	1.00
263_V	271_V	0.707	1.00
99_D	131_E	0.707	1.00
420_F	439_L	0.706	1.00
37_Y	258_A	0.705	1.00
17_A	21_P	0.705	1.00
10_G	80_A	0.704	1.00
47_T	51_L	0.704	1.00
483_A	539_T	0.703	1.00
66_A	72_W	0.702	1.00
494_V	499_L	0.702	1.00
284_H	337_A	0.700	1.00
49_K	180_L	0.700	1.00
471_V	539_T	0.699	1.00
187_L	212_H	0.698	1.00
242_H	448_E	0.696	1.00
373_K	394_R	0.695	1.00
291_I	324_A	0.694	1.00
425_A	433_C	0.691	1.00
22_D	36_T	0.690	1.00
275_V	280_C	0.687	1.00
374_I	427_M	0.687	1.00
57_G	84_A	0.686	1.00
51_L	109_A	0.686	1.00
458_F	502_Y	0.686	1.00
326_I	354_D	0.685	1.00
55_G	84_A	0.685	1.00
425_A	436_T	0.684	1.00
104_Q	403_Y	0.681	1.00
48_A	78_A	0.679	1.00
46_Q	180_L	0.679	1.00
76_Q	80_A	0.679	1.00
337_A	346_V	0.679	1.00
65_W	116_Y	0.678	1.00
63_A	105_S	0.675	1.00
237_P	286_V	0.675	1.00
367_L	370_T	0.675	1.00
52_M	185_N	0.674	1.00
273_K	276_E	0.673	1.00
13_L	41_D	0.672	1.00
409_T	413_I	0.671	1.00
10_G	14_E	0.668	1.00
343_A	347_I	0.667	1.00
247_V	345_P	0.667	1.00
336_I	361_E	0.667	1.00
452_P	532_K	0.666	1.00
466_L	488_L	0.662	1.00
503_C	507_I	0.661	1.00
69_I	113_M	0.661	1.00
57_G	108_A	0.658	1.00
441_D	456_E	0.658	1.00
228_L	258_A	0.655	1.00
235_C	274_T	0.653	1.00
49_K	178_A	0.652	1.00
275_V	283_L	0.650	1.00
62_V	109_A	0.648	1.00
338_Y	347_I	0.648	1.00
34_R	259_A	0.646	1.00
440_K	480_E	0.645	1.00
16_T	257_G	0.644	1.00
214_N	400_K	0.644	1.00
283_L	310_G	0.644	1.00
223_A	252_A	0.644	1.00
475_D	478_F	0.644	1.00
385_R	429_E	0.643	1.00
225_C	368_P	0.642	1.00
291_I	295_H	0.640	1.00
465_V	486_I	0.639	1.00
229_T	308_R	0.639	1.00
301_A	304_L	0.639	1.00
49_K	181_E	0.638	1.00
316_P	435_I	0.637	1.00
94_Q	97_E	0.637	1.00
52_M	184_M	0.636	1.00
130_P	133_Q	0.636	1.00
218_N	346_V	0.635	1.00
393_T	398_V	0.634	1.00
473_V	481_E	0.633	1.00
85_V	195_M	0.633	1.00
273_K	302_Y	0.631	1.00
276_E	306_T	0.630	1.00
271_V	275_V	0.630	1.00
300_D	328_R	0.630	1.00
218_N	248_L	0.630	1.00
465_V	468_V	0.627	1.00
45_R	182_E	0.627	1.00
266_F	271_V	0.625	1.00
85_V	403_Y	0.625	1.00
394_R	417_G	0.624	1.00
523_P	535_L	0.623	1.00
76_Q	251_L	0.623	1.00
45_R	181_E	0.622	1.00
509_R	512_I	0.622	1.00
335_T	351_R	0.622	1.00
480_E	536_R	0.621	1.00
235_C	275_V	0.620	1.00
445_R	478_F	0.618	1.00
238_V	284_H	0.617	1.00
44_C	48_A	0.617	1.00
58_K	187_L	0.616	1.00
47_T	50_G	0.616	1.00
31_R	43_L	0.615	1.00
190_D	400_K	0.615	1.00
104_Q	207_G	0.614	1.00
61_H	404_K	0.614	1.00
66_A	75_V	0.614	1.00
182_E	185_N	0.613	1.00
71_E	113_M	0.613	1.00
469_Q	532_K	0.612	1.00
363_T	425_A	0.612	1.00
276_E	305_S	0.612	1.00
12_L	216_I	0.610	1.00
398_V	419_L	0.609	1.00
375_V	418_W	0.608	1.00
28_Y	264_Q	0.608	1.00
35_Y	39_Q	0.608	1.00
222_I	248_L	0.608	1.00
485_W	517_I	0.607	1.00
453_R	456_E	0.606	1.00
399_M	412_A	0.605	1.00
466_L	490_D	0.605	1.00
234_M	258_A	0.605	1.00
58_K	185_N	0.603	1.00
291_I	320_E	0.603	1.00
248_L	284_H	0.602	1.00
234_M	282_V	0.602	1.00
87_V	197_Y	0.601	1.00
76_Q	250_V	0.600	1.00
49_K	182_E	0.600	1.00
459_L	470_V	0.600	1.00
50_G	178_A	0.599	1.00
77_F	251_L	0.599	1.00
351_R	354_D	0.599	1.00
44_C	47_T	0.598	1.00
228_L	232_D	0.598	1.00
109_A	152_I	0.597	1.00
414_N	417_G	0.597	1.00
383_V	386_G	0.596	1.00
236_I	249_G	0.594	1.00
219_A	251_L	0.594	1.00
452_P	472_G	0.592	1.00
88_T	196_Q	0.592	1.00
12_L	255_S	0.590	1.00
236_I	260_M	0.589	1.00
61_H	107_A	0.589	1.00
52_M	182_E	0.589	1.00
455_I	482_A	0.588	1.00
46_Q	49_K	0.588	1.00
24_D	233_R	0.584	1.00
467_D	522_Y	0.584	1.00
239_P	242_H	0.584	1.00
45_R	52_M	0.583	1.00
244_F	311_I	0.582	1.00
20_Y	257_G	0.581	1.00
428_D	431_G	0.581	1.00
64_I	79_T	0.580	1.00
241_F	448_E	0.579	1.00
203_G	451_Y	0.577	1.00
66_A	112_I	0.576	1.00
405_D	411_K	0.576	1.00
66_A	113_M	0.576	1.00
464_A	502_Y	0.575	1.00
275_V	279_K	0.574	1.00
444_I	451_Y	0.572	1.00
458_F	507_I	0.572	1.00
26_V	260_M	0.571	1.00
517_I	538_K	0.570	1.00
325_V	334_I	0.569	1.00
27_V	30_D	0.567	1.00
74_A	165_W	0.567	1.00
348_T	363_T	0.567	1.00
18_D	41_D	0.564	1.00
340_Q	343_A	0.563	1.00
218_N	222_I	0.563	1.00
512_I	516_V	0.562	1.00
26_V	35_Y	0.561	1.00
287_P	315_S	0.559	1.00
259_A	278_E	0.558	1.00
249_G	284_H	0.558	1.00
340_Q	421_T	0.554	1.00
105_S	207_G	0.554	1.00
64_I	72_W	0.553	1.00
313_A	337_A	0.553	1.00
297_P	300_D	0.552	1.00
375_V	380_C	0.552	1.00
284_H	313_A	0.552	1.00
272_L	304_L	0.552	1.00
471_V	536_R	0.551	1.00
323_K	326_I	0.549	1.00
468_V	503_C	0.549	1.00
392_C	414_N	0.548	1.00
459_L	503_C	0.547	1.00
129_I	133_Q	0.544	1.00
401_G	406_K	0.543	1.00
495_S	518_F	0.542	1.00
462_H	465_V	0.542	1.00
312_M	334_I	0.542	1.00
321_V	324_A	0.541	1.00
194_N	215_V	0.540	1.00
317_C	336_I	0.540	1.00
437_G	452_P	0.539	1.00
112_I	117_R	0.539	1.00
500_K	503_C	0.538	1.00
100_Y	105_S	0.538	1.00
248_L	346_V	0.537	1.00
236_I	262_P	0.537	1.00
388_Q	439_L	0.537	1.00
195_M	209_M	0.536	1.00
456_E	484_A	0.536	1.00
406_K	409_T	0.536	1.00
56_I	108_A	0.534	1.00
382_E	392_C	0.533	1.00
386_G	426_V	0.533	1.00
14_E	44_C	0.533	1.00
326_I	333_D	0.533	1.00
274_T	277_K	0.532	1.00
14_E	182_E	0.530	1.00
237_P	285_G	0.530	1.00
204_F	405_D	0.530	1.00
85_V	88_T	0.528	1.00
179_E	183_R	0.528	1.00
382_E	427_M	0.528	1.00
183_R	187_L	0.528	1.00
457_E	461_Q	0.527	1.00
313_A	346_V	0.527	1.00
105_S	195_M	0.527	1.00
24_D	278_E	0.525	1.00
443_L	472_G	0.525	1.00
380_C	383_V	0.524	1.00
387_M	426_V	0.523	1.00
271_V	289_M	0.522	1.00
191_N	212_H	0.522	1.00
445_R	480_E	0.522	1.00
59_G	84_A	0.521	1.00
87_V	101_L	0.520	1.00
51_L	84_A	0.520	1.00
220_A	255_S	0.519	1.00
312_M	336_I	0.519	1.00
117_R	153_Y	0.518	1.00
180_L	183_R	0.518	1.00
65_W	89_V	0.517	1.00
246_C	250_V	0.517	1.00
216_I	220_A	0.517	1.00
233_R	236_I	0.516	1.00
202_T	206_K	0.516	1.00
10_G	17_A	0.516	1.00
89_V	102_L	0.515	1.00
93_Y	241_F	0.514	1.00
26_V	40_F	0.514	1.00
11_R	186_S	0.514	1.00
218_N	347_I	0.513	1.00
328_R	331_M	0.513	1.00
37_Y	254_V	0.512	1.00
44_C	77_F	0.511	1.00
228_L	252_A	0.511	1.00
337_A	349_Q	0.510	1.00
47_T	165_W	0.510	1.00
150_T	153_Y	0.509	1.00
51_L	55_G	0.508	1.00
208_V	341_T	0.507	1.00
50_G	152_I	0.506	1.00
473_V	485_W	0.506	1.00
266_F	292_A	0.506	1.00
97_E	454_E	0.506	1.00
59_G	192_V	0.506	1.00
20_Y	230_S	0.505	1.00
229_T	281_T	0.504	1.00
13_L	44_C	0.504	1.00
294_L	321_V	0.504	1.00
287_P	321_V	0.504	1.00
455_I	513_P	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tsyA	2	0.765	100	0.128	Contact Map
2d1sA	1	0.949	100	0.139	Contact Map
1mdbA	1	0.9381	100	0.139	Contact Map
3ni2A	1	0.9308	100	0.146	Contact Map
3rixA	1	0.745	100	0.151	Contact Map
1ry2A	1	0.9508	100	0.155	Contact Map
3etcA	2	0.9053	100	0.157	Contact Map
1pg4A	1	0.9654	100	0.157	Contact Map
3g7sA	2	0.8543	100	0.163	Contact Map
3o83A	1	0.7559	100	0.163	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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