GREMLIN Database
YNZC - UPF0291 protein YnzC
UniProt: O31818 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 77 (71)
Sequences: 415 (273)
Seq/√Len: 32.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_K36_E3.3711.00
50_K70_E3.2651.00
9_R29_E3.1291.00
15_A19_A2.6421.00
31_Q35_Q2.2700.99
45_M48_T2.2670.99
65_E69_R2.2650.99
4_N8_A2.2340.99
55_I61_D2.1630.99
16_K20_G2.0780.98
30_Q34_R1.7720.95
46_K50_K1.7190.94
16_K21_V1.4570.88
49_L67_L1.4330.87
17_A30_Q1.4330.87
49_L74_N1.4150.86
40_G43_S1.3980.85
27_K30_Q1.3800.85
48_T52_V1.3470.83
16_K26_E1.3330.82
69_R73_N1.3090.81
50_K74_N1.2900.80
44_S47_N1.2840.80
49_L52_V1.2630.79
7_I37_Y1.2510.78
53_K61_D1.2300.77
27_K31_Q1.2240.77
57_P67_L1.2010.75
41_F45_M1.1920.75
46_K49_L1.1580.73
67_L71_Q1.1220.70
53_K68_K1.0450.64
17_A27_K1.0200.63
56_D60_N1.0190.63
9_R12_E1.0180.62
48_T54_I1.0090.62
13_L29_E1.0070.62
19_A24_E0.9990.61
47_N51_S0.9810.60
46_K70_E0.9720.59
70_E73_N0.9230.55
41_F44_S0.9120.54
57_P60_N0.9030.53
51_S55_I0.8760.51
32_K35_Q0.8490.49
53_K72_R0.8410.48
70_E74_N0.8210.46
22_I30_Q0.8010.45
40_G45_M0.8010.45
61_D64_P0.7660.42
37_Y53_K0.7530.41
57_P61_D0.7460.40
41_F49_L0.7440.40
67_L70_E0.7400.40
65_E73_N0.7220.38
28_A31_Q0.7110.38
12_E24_E0.7090.37
27_K35_Q0.7080.37
14_A34_R0.7070.37
51_S67_L0.7060.37
45_M54_I0.7030.37
10_I21_V0.6890.36
37_Y40_G0.6820.35
9_R13_L0.6810.35
61_D71_Q0.6790.35
5_A24_E0.6700.34
8_A12_E0.6680.34
43_S72_R0.6570.34
45_M68_K0.6520.33
28_A32_K0.6490.33
49_L70_E0.6470.33
53_K57_P0.6390.32
25_E52_V0.6370.32
17_A34_R0.6360.32
6_K9_R0.6300.32
14_A37_Y0.6260.31
6_K40_G0.6250.31
65_E72_R0.6250.31
14_A17_A0.6210.31
14_A64_P0.6170.31
18_K37_Y0.6120.30
21_V30_Q0.6090.30
24_E27_K0.6080.30
38_L54_I0.6030.30
7_I18_K0.5960.29
45_M49_L0.5890.29
41_F50_K0.5840.28
48_T51_S0.5770.28
28_A68_K0.5680.27
44_S48_T0.5660.27
51_S61_D0.5590.27
41_F51_S0.5570.27
61_D68_K0.5460.26
22_I27_K0.5370.25
10_I22_I0.5350.25
4_N17_A0.5280.25
51_S72_R0.5260.25
57_P71_Q0.5200.24
39_K60_N0.5140.24
28_A48_T0.5090.24
7_I39_K0.5090.24
7_I24_E0.5080.24
36_E42_R0.5040.23
36_E48_T0.5030.23
5_A12_E0.5000.23
31_Q39_K0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hepA 1 0.5455 100 0.073 Contact Map
3bhpA 3 0.7013 99.8 0.41 Contact Map
2jvdA 1 0.6234 99.7 0.46 Contact Map
4im9A 1 0.5714 54.1 0.882 Contact Map
1t3wA 4 0.5195 52.1 0.883 Contact Map
3r15A 1 0.7532 41.9 0.89 Contact Map
3b0cT 1 0.6883 19.3 0.907 Contact Map
4n2kA 2 0.961 18.6 0.908 Contact Map
2dewX 2 1 18.6 0.908 Contact Map
1t11A 3 0.9221 17.6 0.909 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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