GREMLIN Database
YMAC - UPF0714 protein YmaC
UniProt: O31789 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 235 (197)
Sequences: 179 (149)
Seq/√Len: 10.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
139_T222_Y5.4371.00
198_Q222_Y4.1100.99
46_E97_K4.0800.99
97_K103_T3.7770.99
139_T198_Q3.4140.97
68_P140_L2.7730.91
126_V184_G2.6940.90
91_Y111_F2.6760.89
95_G101_N2.4000.83
134_G195_S2.3960.83
132_Y195_S2.3200.81
67_S77_V2.3060.80
91_Y113_E2.2970.80
194_I230_L2.2320.78
66_M120_I2.1290.75
39_F106_I2.1240.74
127_V148_R2.1230.74
68_P81_V2.1160.74
97_K106_I2.0770.73
41_S45_N1.9930.69
91_Y114_P1.9880.69
68_P128_A1.9570.68
68_P169_K1.9470.68
66_M116_A1.8920.65
78_S174_G1.8640.64
85_N90_T1.8380.63
64_L126_V1.8360.63
40_S106_I1.8150.62
78_S94_E1.8120.62
64_L181_N1.8000.61
67_S81_V1.7820.60
156_L161_F1.7490.59
144_T189_S1.7420.59
46_E51_Y1.6460.54
189_S229_V1.6430.54
131_G199_R1.6410.54
211_R214_T1.6300.53
202_F216_N1.6300.53
163_A194_I1.6030.52
55_Y192_L1.5200.48
150_K192_L1.5090.48
83_Y223_V1.4910.47
110_N177_A1.4680.46
39_F111_F1.4660.46
91_Y156_L1.4370.44
76_G79_E1.4310.44
145_D186_T1.4270.44
116_A180_I1.4160.43
63_V127_V1.4150.43
181_N189_S1.3790.42
140_L169_K1.3630.41
72_R99_H1.3590.41
51_Y163_A1.3560.40
216_N219_F1.3300.39
109_T176_N1.3100.38
53_I113_E1.3090.38
98_S197_E1.2970.38
89_S92_L1.2950.38
153_V163_A1.2810.37
152_I190_I1.2790.37
84_F226_I1.2750.37
41_S68_P1.2640.36
89_S123_H1.2520.36
65_I178_E1.2500.36
105_H193_E1.2100.34
140_L172_L1.2080.34
132_Y198_Q1.1910.33
89_S113_E1.1750.33
105_H130_H1.1690.32
130_H193_E1.1690.32
65_I78_S1.1670.32
197_E201_A1.1550.32
111_F114_P1.1540.32
51_Y92_L1.1450.31
96_L170_S1.1290.31
52_D108_S1.1210.30
149_A229_V1.1070.30
57_E141_V1.1050.30
39_F91_Y1.1050.30
116_A120_I1.1030.30
128_A145_D1.1010.30
72_R203_F1.0890.29
64_L123_H1.0780.29
86_N227_K1.0750.29
77_V179_N1.0720.28
64_L119_K1.0660.28
112_D160_G1.0640.28
158_R228_G1.0640.28
121_K133_K1.0620.28
99_H111_F1.0530.28
106_I111_F1.0500.28
72_R100_D1.0480.28
67_S85_N1.0480.28
207_Y214_T1.0440.27
126_V152_I1.0250.27
206_F216_N1.0250.27
129_F222_Y1.0240.27
90_T106_I1.0210.27
95_G190_I1.0030.26
77_V81_V0.9830.25
37_S41_S0.9630.24
34_D110_N0.9590.24
156_L202_F0.9550.24
52_D94_E0.9550.24
36_Y161_F0.9540.24
225_A229_V0.9520.24
117_K195_S0.9490.24
141_V163_A0.9390.24
103_T106_I0.9370.24
36_Y46_E0.9350.23
75_G123_H0.9230.23
137_K218_E0.9220.23
111_F219_F0.9120.23
148_R189_S0.9060.23
78_S183_Q0.8950.22
154_R216_N0.8870.22
141_V217_S0.8770.22
47_S210_N0.8750.21
35_T103_T0.8740.21
110_N162_S0.8730.21
83_Y183_Q0.8720.21
149_A165_L0.8710.21
139_T156_L0.8670.21
54_S94_E0.8540.21
166_A229_V0.8490.21
43_A106_I0.8450.21
119_K214_T0.8350.20
161_F202_F0.8340.20
107_T130_H0.8250.20
153_V172_L0.8240.20
100_D207_Y0.8220.20
80_L89_S0.8210.20
172_L225_A0.8200.20
76_G139_T0.8180.20
152_I156_L0.8170.20
95_G123_H0.8170.20
106_I127_V0.8160.20
135_E160_G0.8090.19
38_N106_I0.8090.19
141_V181_N0.8080.19
77_V119_K0.8030.19
51_Y166_A0.8000.19
127_V224_S0.7980.19
120_I123_H0.7860.19
118_K145_D0.7860.19
218_E224_S0.7830.19
35_T47_S0.7830.19
100_D133_K0.7830.19
129_F152_I0.7740.18
93_F179_N0.7620.18
51_Y116_A0.7610.18
33_P187_G0.7590.18
189_S206_F0.7570.18
110_N164_E0.7560.18
96_L230_L0.7550.18
91_Y106_I0.7530.18
207_Y211_R0.7500.18
39_F43_A0.7490.18
63_V187_G0.7430.18
74_E179_N0.7420.18
125_Y188_L0.7400.17
198_Q201_A0.7400.17
56_N90_T0.7370.17
111_F224_S0.7330.17
61_S202_F0.7310.17
59_K120_I0.7290.17
88_Y202_F0.7230.17
98_S231_E0.7200.17
107_T193_E0.7130.17
132_Y222_Y0.7110.17
66_M126_V0.7080.17
54_S82_R0.7080.17
174_G191_Q0.7040.17
46_E103_T0.7030.17
126_V190_I0.7030.17
83_Y86_N0.7010.16
80_L139_T0.7000.16
39_F113_E0.6990.16
217_S221_A0.6990.16
74_E131_G0.6990.16
171_G200_E0.6980.16
163_A169_K0.6940.16
178_E205_D0.6940.16
106_I113_E0.6910.16
152_I222_Y0.6900.16
171_G183_Q0.6890.16
67_S84_F0.6870.16
52_D95_G0.6860.16
201_A230_L0.6840.16
97_K101_N0.6820.16
106_I161_F0.6800.16
44_E210_N0.6800.16
153_V212_K0.6780.16
212_K230_L0.6770.16
220_Y223_V0.6760.16
72_R184_G0.6700.16
68_P180_I0.6660.16
77_V84_F0.6650.16
46_E50_D0.6630.15
161_F218_E0.6620.15
36_Y76_G0.6610.15
94_E226_I0.6590.15
181_N229_V0.6570.15
39_F190_I0.6570.15
46_E222_Y0.6540.15
34_D144_T0.6520.15
80_L221_A0.6490.15
43_A97_K0.6470.15
202_F218_E0.6460.15
64_L125_Y0.6290.15
76_G97_K0.6280.15
80_L202_F0.6270.15
169_K195_S0.6250.15
82_R229_V0.6240.15
61_S151_M0.6210.14
90_T189_S0.6150.14
127_V226_I0.6120.14
119_K159_R0.6110.14
202_F210_N0.6100.14
80_L129_F0.6070.14
34_D107_T0.6070.14
126_V221_A0.6050.14
120_I126_V0.6040.14
51_Y190_I0.6030.14
105_H108_S0.6010.14
108_S193_E0.6010.14
202_F207_Y0.6000.14
40_S211_R0.5990.14
65_I222_Y0.5970.14
134_G197_E0.5960.14
35_T218_E0.5950.14
73_I130_H0.5930.14
116_A194_I0.5920.14
81_V90_T0.5920.14
108_S130_H0.5900.14
41_S133_K0.5880.14
100_D110_N0.5870.14
59_K119_K0.5850.14
140_L163_A0.5830.14
218_E228_G0.5810.14
80_L163_A0.5790.14
109_T160_G0.5790.14
210_N214_T0.5770.13
194_I209_K0.5730.13
76_G222_Y0.5730.13
127_V210_N0.5720.13
81_V145_D0.5690.13
48_P63_V0.5690.13
56_N156_L0.5680.13
106_I112_D0.5650.13
161_F221_A0.5650.13
48_P78_S0.5640.13
210_N221_A0.5600.13
39_F94_E0.5600.13
152_I179_N0.5570.13
75_G180_I0.5570.13
192_L228_G0.5570.13
62_K158_R0.5560.13
67_S90_T0.5540.13
198_Q202_F0.5510.13
43_A113_E0.5500.13
113_E184_G0.5500.13
119_K195_S0.5490.13
48_P207_Y0.5480.13
166_A225_A0.5460.13
70_G174_G0.5410.13
101_N202_F0.5390.13
97_K195_S0.5370.13
190_I225_A0.5370.13
89_S175_L0.5370.13
89_S180_I0.5350.13
67_S119_K0.5330.13
94_E214_T0.5310.13
46_E89_S0.5300.12
38_N224_S0.5280.12
159_R228_G0.5260.12
41_S100_D0.5260.12
37_S99_H0.5250.12
36_Y97_K0.5240.12
174_G219_F0.5220.12
70_G76_G0.5190.12
78_S129_F0.5180.12
38_N221_A0.5160.12
214_T225_A0.5150.12
121_K135_E0.5130.12
211_R216_N0.5110.12
110_N201_A0.5100.12
64_L189_S0.5080.12
63_V228_G0.5080.12
50_D65_I0.5070.12
97_K197_E0.5070.12
34_D64_L0.5040.12
65_I201_A0.5030.12
148_R190_I0.5030.12
65_I83_Y0.5010.12
159_R176_N0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3a9lA 2 0.8468 100 0.223 Contact Map
2odfA 2 0.7745 95.1 0.932 Contact Map
2q7sA 1 0.7362 88.7 0.944 Contact Map
3czxA 2 0.6681 59 0.957 Contact Map
3qayA 1 0.6553 42.5 0.961 Contact Map
4lq6A 1 0.6851 33.6 0.963 Contact Map
1xovA 1 0.6596 32.2 0.963 Contact Map
2ki0A 1 0.1532 22.8 0.966 Contact Map
2xdqB 2 0.5787 22.5 0.966 Contact Map
4rn7A 1 0.6638 21.3 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0083 seconds.