MIAB - BACSU - GREMLIN Contacts

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MIAB - tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase

UniProt:	O31778	Sequences: MNEKQKLESGQVHPSDKKSEKDYSKYFEAVYIPPSLKDAKKRGKEAVTYHNDFKISEQFKGLGDGRKFYIRTYGCQMNEHDTEVMAGIFMALGYEATNSVDDANVILLNTCAIRENAENKVFGELGHLKALKKNNPDLILGVCGCMSQEESVVNRILKKHPFVDMIFGTHNIHRLPELLSEAYLSKEMVVEVWSKEGDVIENLPKVRNGKIKGWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEVRRLASEGYKEITLLGQNVNAYGKDFEDMTYGLGDLMDELRKIDIPRIRFTTSHPRDFDDRLIEVLAKGGNLLDHIHLPVQSGSSEVLKLMARKYDRERYMELVRKIKEAMPNASLTTDIIVGFPNETDEQFEETLSLYREVEFDSAYTFIYSPREGTPAAKMKDNVPMRVKKERLQRLNALVNEISAKKMKEYEGKVVEVLVEGESKNNPDILAGYTEKSKLVNFKGPKEAIGKIVRVKIQQAKTWSLDGEMVGEAIEVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	509 (429)
Sequences:	7175 (4167)
Seq/√Len:	201.2

ECOLI - MIAB RIMO
BACSU - MIAB MTAB
HALSA - Q9HP07
SULSO - Q97W60 Q97ZV0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
253_A	293_I	3.745	1.00
332_S	379_Q	3.576	1.00
333_S	346_E	3.516	1.00
215_V	249_V	3.427	1.00
332_S	382_E	3.395	1.00
448_E	486_R	3.236	1.00
391_E	437_K	3.213	1.00
289_R	317_G	3.106	1.00
308_D	354_K	3.084	1.00
446_V	486_R	3.083	1.00
490_Q	500_E	3.043	1.00
349_M	389_E	2.971	1.00
334_E	379_Q	2.954	1.00
488_K	500_E	2.920	1.00
312_E	358_A	2.900	1.00
451_V	474_F	2.876	1.00
422_E	426_R	2.649	1.00
384_L	430_L	2.633	1.00
287_E	290_K	2.607	1.00
388_R	433_E	2.517	1.00
334_E	338_L	2.455	1.00
385_S	389_E	2.446	1.00
446_V	488_K	2.416	1.00
286_D	316_K	2.341	1.00
249_V	260_I	2.264	1.00
349_M	390_V	2.263	1.00
249_V	288_L	2.194	1.00
419_V	422_E	2.186	1.00
72_T	82_T	2.183	1.00
355_I	362_A	2.183	1.00
324_I	362_A	2.162	1.00
247_Q	250_R	2.153	1.00
174_R	177_E	2.135	1.00
388_R	430_L	2.110	1.00
350_E	353_R	2.104	1.00
258_K	294_P	2.079	1.00
402_P	414_N	2.043	1.00
312_E	316_K	2.005	1.00
67_K	95_E	1.996	1.00
322_D	467_E	1.989	1.00
385_S	388_R	1.987	1.00
377_D	419_V	1.986	1.00
380_F	426_R	1.982	1.00
315_A	358_A	1.974	1.00
250_R	254_S	1.972	1.00
416_P	419_V	1.962	1.00
448_E	484_I	1.945	1.00
345_R	382_E	1.932	1.00
289_R	319_N	1.932	1.00
399_I	424_L	1.909	1.00
353_R	389_E	1.907	1.00
480_A	483_K	1.894	1.00
345_R	349_M	1.891	1.00
443_E	492_A	1.868	1.00
384_L	426_R	1.866	1.00
253_A	291_I	1.849	1.00
294_P	448_E	1.840	1.00
92_L	180_S	1.822	1.00
242_P	287_E	1.813	1.00
289_R	318_G	1.789	1.00
381_E	385_S	1.787	1.00
154_N	158_K	1.776	1.00
436_A	440_K	1.769	1.00
353_R	357_E	1.758	1.00
99_S	102_D	1.744	1.00
328_V	386_L	1.739	1.00
391_E	434_I	1.718	1.00
438_K	441_E	1.712	1.00
347_R	350_E	1.701	1.00
330_S	383_T	1.687	1.00
417_M	420_K	1.673	1.00
448_E	467_E	1.668	1.00
402_P	409_A	1.659	1.00
381_E	426_R	1.641	1.00
70_I	82_T	1.626	1.00
449_V	464_G	1.625	1.00
344_D	347_R	1.604	1.00
451_V	485_V	1.588	1.00
335_V	338_L	1.579	1.00
346_E	350_E	1.578	1.00
224_F	236_K	1.578	1.00
345_R	385_S	1.572	1.00
472_V	489_I	1.565	1.00
286_D	317_G	1.563	1.00
280_G	283_D	1.562	1.00
376_T	379_Q	1.559	1.00
333_S	345_R	1.557	1.00
286_D	313_V	1.550	1.00
322_D	361_N	1.548	1.00
442_Y	447_V	1.548	1.00
377_D	381_E	1.545	1.00
68_F	96_A	1.531	1.00
280_G	309_R	1.526	1.00
313_V	317_G	1.516	1.00
393_D	438_K	1.513	1.00
141_G	165_M	1.511	1.00
132_K	164_D	1.505	1.00
147_S	166_I	1.501	1.00
379_Q	382_E	1.491	1.00
311_I	355_I	1.476	1.00
112_A	233_T	1.443	1.00
324_I	355_I	1.396	1.00
107_L	141_G	1.386	1.00
130_A	133_K	1.385	1.00
85_M	143_C	1.380	1.00
289_R	313_V	1.376	1.00
260_I	293_I	1.376	1.00
241_R	244_D	1.375	1.00
226_T	372_F	1.372	1.00
345_R	386_L	1.366	1.00
487_V	499_G	1.365	1.00
251_R	255_E	1.361	1.00
461_I	475_K	1.356	1.00
247_Q	251_R	1.355	1.00
382_E	385_S	1.339	1.00
226_T	340_A	1.334	1.00
421_K	425_Q	1.334	1.00
368_I	387_Y	1.316	1.00
240_R	248_E	1.314	1.00
282_G	313_V	1.309	1.00
285_M	320_L	1.307	1.00
308_D	312_E	1.304	1.00
338_L	379_Q	1.301	1.00
286_D	309_R	1.295	1.00
277_M	280_G	1.293	1.00
425_Q	429_A	1.292	1.00
246_I	250_R	1.290	1.00
246_I	287_E	1.290	1.00
361_N	445_K	1.278	1.00
314_L	320_L	1.278	1.00
338_L	411_M	1.276	1.00
391_E	438_K	1.273	1.00
171_N	174_R	1.263	1.00
440_K	443_E	1.256	1.00
224_F	232_Y	1.255	1.00
491_Q	498_D	1.248	1.00
283_D	309_R	1.247	1.00
387_Y	427_L	1.247	1.00
407_P	410_K	1.233	1.00
430_L	434_I	1.232	1.00
417_M	421_K	1.231	1.00
313_V	320_L	1.225	1.00
442_Y	445_K	1.219	1.00
240_R	244_D	1.217	1.00
397_T	424_L	1.217	1.00
378_E	382_E	1.207	1.00
112_A	118_E	1.206	1.00
67_K	102_D	1.205	1.00
125_L	142_V	1.184	1.00
338_L	372_F	1.183	1.00
110_T	142_V	1.182	1.00
251_R	254_S	1.179	1.00
288_L	296_I	1.174	1.00
377_D	426_R	1.174	1.00
399_I	417_M	1.173	1.00
359_M	362_A	1.170	1.00
485_V	501_M	1.169	1.00
271_G	274_F	1.156	1.00
429_A	433_E	1.151	1.00
283_D	287_E	1.148	1.00
489_I	497_L	1.147	1.00
350_E	354_K	1.145	1.00
431_V	434_I	1.144	1.00
399_I	421_K	1.143	1.00
317_G	320_L	1.143	1.00
462_L	476_G	1.138	1.00
338_L	374_N	1.133	1.00
70_I	107_L	1.132	1.00
229_I	233_T	1.129	1.00
354_K	357_E	1.125	1.00
165_M	182_A	1.125	1.00
340_A	407_P	1.124	1.00
67_K	97_T	1.123	1.00
296_I	319_N	1.119	1.00
292_D	319_N	1.104	1.00
381_E	384_L	1.102	1.00
148_Q	168_G	1.102	1.00
447_V	489_I	1.096	1.00
352_V	364_L	1.096	1.00
447_V	466_T	1.087	1.00
314_L	359_M	1.085	1.00
378_E	381_E	1.084	1.00
115_E	119_N	1.083	1.00
290_K	317_G	1.082	1.00
333_S	344_D	1.082	1.00
119_N	123_G	1.080	1.00
370_V	380_F	1.079	1.00
143_C	167_F	1.072	1.00
181_E	186_K	1.072	1.00
89_F	179_L	1.065	1.00
165_M	178_L	1.063	1.00
351_L	354_K	1.063	1.00
311_I	358_A	1.058	1.00
222_D	236_K	1.054	1.00
440_K	492_A	1.049	1.00
242_P	246_I	1.045	1.00
387_Y	395_A	1.044	1.00
71_R	124_E	1.044	1.00
240_R	245_I	1.042	1.00
323_H	469_S	1.041	1.00
397_T	428_N	1.039	1.00
139_I	182_A	1.039	1.00
289_R	320_L	1.034	1.00
167_F	178_L	1.032	1.00
267_V	298_F	1.030	1.00
135_N	138_L	1.027	1.00
368_I	395_A	1.025	1.00
391_E	441_E	1.024	1.00
309_R	312_E	1.021	1.00
106_I	138_L	1.019	1.00
226_T	407_P	1.017	1.00
258_K	484_I	1.017	1.00
465_Y	471_L	1.016	1.00
215_V	245_I	1.012	1.00
414_N	420_K	1.012	1.00
281_L	310_L	1.009	1.00
374_N	413_D	1.008	1.00
229_I	232_Y	1.007	1.00
433_E	437_K	1.005	1.00
380_F	427_L	0.997	1.00
366_T	392_F	0.996	1.00
352_V	390_V	0.994	1.00
356_K	391_E	0.993	1.00
315_A	359_M	0.988	1.00
395_A	431_V	0.986	1.00
333_S	382_E	0.985	1.00
439_M	470_K	0.980	1.00
250_R	292_D	0.980	1.00
311_I	359_M	0.978	1.00
130_A	134_N	0.976	1.00
454_E	462_L	0.975	1.00
155_R	158_K	0.974	1.00
443_E	491_Q	0.973	1.00
430_L	433_E	0.973	1.00
149_E	233_T	0.972	1.00
244_D	247_Q	0.963	0.99
126_G	129_K	0.962	0.99
370_V	424_L	0.960	0.99
436_A	492_A	0.960	0.99
361_N	441_E	0.958	0.99
69_Y	100_V	0.944	0.99
285_M	317_G	0.941	0.99
156_I	163_V	0.940	0.99
163_V	166_I	0.940	0.99
314_L	324_I	0.938	0.99
213_G	252_L	0.936	0.99
70_I	86_A	0.935	0.99
68_F	94_Y	0.935	0.99
218_M	237_E	0.935	0.99
258_K	483_K	0.935	0.99
384_L	388_R	0.934	0.99
110_T	121_V	0.933	0.99
139_I	183_Y	0.930	0.99
472_V	499_G	0.926	0.99
366_T	395_A	0.925	0.99
354_K	358_A	0.923	0.99
387_Y	392_F	0.919	0.99
108_L	125_L	0.917	0.99
279_Y	287_E	0.913	0.99
68_F	86_A	0.909	0.99
377_D	422_E	0.908	0.99
332_S	335_V	0.904	0.99
451_V	464_G	0.903	0.99
424_L	428_N	0.900	0.99
279_Y	283_D	0.899	0.99
436_A	439_M	0.892	0.99
86_A	96_A	0.888	0.99
215_V	260_I	0.885	0.99
151_S	154_N	0.879	0.99
294_P	484_I	0.875	0.99
347_R	351_L	0.875	0.99
338_L	413_D	0.873	0.99
473_N	496_S	0.873	0.99
392_F	395_A	0.870	0.99
243_E	247_Q	0.870	0.99
462_L	479_E	0.870	0.99
252_L	257_Y	0.870	0.99
372_F	411_M	0.869	0.99
453_G	463_A	0.869	0.99
250_R	287_E	0.868	0.99
275_E	279_Y	0.864	0.99
489_I	499_G	0.863	0.99
282_G	309_R	0.860	0.99
335_V	379_Q	0.859	0.99
72_T	109_N	0.851	0.99
180_S	184_L	0.850	0.99
142_V	163_V	0.849	0.99
177_E	181_E	0.848	0.99
289_R	296_I	0.848	0.99
431_V	435_S	0.847	0.99
334_E	382_E	0.847	0.99
374_N	414_N	0.846	0.99
429_A	432_N	0.845	0.99
66_R	183_Y	0.842	0.99
68_F	90_M	0.841	0.99
435_S	439_M	0.841	0.99
311_I	354_K	0.840	0.99
285_M	310_L	0.839	0.99
97_T	103_A	0.839	0.99
253_A	292_D	0.834	0.98
363_S	468_K	0.834	0.98
282_G	307_D	0.833	0.98
434_I	438_K	0.833	0.98
322_D	359_M	0.832	0.98
211_I	452_E	0.832	0.98
242_P	270_Y	0.831	0.98
479_E	483_K	0.831	0.98
139_I	165_M	0.830	0.98
426_R	430_L	0.830	0.98
365_T	394_S	0.829	0.98
449_V	487_V	0.828	0.98
169_T	172_I	0.827	0.98
450_L	484_I	0.827	0.98
77_M	265_Q	0.826	0.98
250_R	291_I	0.825	0.98
227_Y	343_Y	0.824	0.98
324_I	364_L	0.823	0.98
237_E	269_A	0.822	0.98
73_Y	121_V	0.822	0.98
293_I	319_N	0.822	0.98
466_T	472_V	0.821	0.98
106_I	137_D	0.820	0.98
409_A	414_N	0.819	0.98
222_D	272_K	0.818	0.98
493_K	498_D	0.816	0.98
94_Y	105_V	0.816	0.98
323_H	365_T	0.815	0.98
105_V	139_I	0.815	0.98
73_Y	124_E	0.814	0.98
331_G	382_E	0.814	0.98
348_Y	392_F	0.812	0.98
223_K	266_N	0.812	0.98
432_N	495_W	0.810	0.98
451_V	462_L	0.810	0.98
213_G	257_Y	0.809	0.98
181_E	185_S	0.809	0.98
328_V	368_I	0.809	0.98
386_L	390_V	0.806	0.98
368_I	427_L	0.803	0.98
454_E	478_K	0.801	0.98
105_V	141_G	0.799	0.98
118_E	150_E	0.798	0.98
249_V	291_I	0.798	0.98
294_P	319_N	0.795	0.98
349_M	353_R	0.795	0.98
150_E	155_R	0.792	0.98
286_D	290_K	0.789	0.98
215_V	252_L	0.786	0.98
387_Y	434_I	0.785	0.98
182_A	185_S	0.782	0.98
476_G	480_A	0.782	0.98
92_L	177_E	0.781	0.98
139_I	179_L	0.780	0.98
475_K	500_E	0.780	0.98
476_G	479_E	0.778	0.98
243_E	275_E	0.773	0.97
346_E	349_M	0.770	0.97
224_F	340_A	0.769	0.97
411_M	414_N	0.769	0.97
69_Y	97_T	0.768	0.97
474_F	487_V	0.764	0.97
442_Y	468_K	0.761	0.97
370_V	427_L	0.761	0.97
388_R	434_I	0.760	0.97
312_E	315_A	0.759	0.97
129_K	140_L	0.758	0.97
298_F	314_L	0.757	0.97
328_V	348_Y	0.756	0.97
131_L	138_L	0.755	0.97
282_G	310_L	0.754	0.97
434_I	437_K	0.753	0.97
307_D	310_L	0.752	0.97
275_E	280_G	0.752	0.97
106_I	131_L	0.751	0.97
306_F	351_L	0.749	0.97
69_Y	103_A	0.748	0.97
295_R	321_L	0.748	0.97
239_S	273_D	0.746	0.97
384_L	427_L	0.745	0.97
246_I	288_L	0.745	0.97
276_D	279_Y	0.744	0.97
283_D	286_D	0.744	0.97
86_A	90_M	0.744	0.97
449_V	472_V	0.743	0.97
381_E	388_R	0.743	0.97
370_V	420_K	0.741	0.97
88_I	176_P	0.740	0.97
331_G	348_Y	0.739	0.97
363_S	393_D	0.737	0.97
232_Y	407_P	0.734	0.97
129_K	133_K	0.733	0.97
380_F	384_L	0.733	0.97
442_Y	470_K	0.732	0.97
218_M	264_G	0.731	0.96
100_V	106_I	0.730	0.96
451_V	487_V	0.730	0.96
85_M	175_L	0.729	0.96
97_T	102_D	0.727	0.96
383_T	427_L	0.725	0.96
437_K	440_K	0.722	0.96
402_P	420_K	0.722	0.96
148_Q	151_S	0.722	0.96
308_D	311_I	0.719	0.96
141_G	167_F	0.719	0.96
66_R	94_Y	0.715	0.96
80_H	216_N	0.707	0.96
269_A	304_R	0.703	0.96
232_Y	405_G	0.703	0.96
306_F	310_L	0.702	0.96
395_A	434_I	0.701	0.96
291_I	319_N	0.700	0.96
83_E	87_G	0.700	0.96
76_Q	468_K	0.700	0.96
212_K	261_T	0.700	0.96
428_N	431_V	0.699	0.95
393_D	470_K	0.696	0.95
182_A	186_K	0.695	0.95
92_L	176_P	0.695	0.95
455_S	460_D	0.694	0.95
82_T	86_A	0.693	0.95
116_N	119_N	0.691	0.95
89_F	107_L	0.689	0.95
432_N	494_T	0.688	0.95
76_Q	263_L	0.688	0.95
243_E	287_E	0.686	0.95
304_R	342_K	0.686	0.95
199_V	204_P	0.686	0.95
246_I	291_I	0.684	0.95
454_E	459_P	0.682	0.95
490_Q	499_G	0.682	0.95
438_K	442_Y	0.680	0.95
69_Y	106_I	0.678	0.95
295_R	484_I	0.678	0.95
94_Y	180_S	0.676	0.95
461_I	473_N	0.674	0.95
191_E	194_S	0.673	0.94
308_D	358_A	0.673	0.94
436_A	494_T	0.670	0.94
269_A	305_D	0.668	0.94
226_T	338_L	0.668	0.94
335_V	372_F	0.667	0.94
223_K	269_A	0.666	0.94
215_V	262_L	0.666	0.94
324_I	359_M	0.665	0.94
214_W	261_T	0.664	0.94
334_E	378_E	0.662	0.94
426_R	429_A	0.662	0.94
455_S	473_N	0.661	0.94
266_N	305_D	0.661	0.94
349_M	386_L	0.660	0.94
113_I	229_I	0.660	0.94
81_D	219_Y	0.656	0.94
387_Y	431_V	0.656	0.94
321_L	467_E	0.655	0.94
116_N	401_S	0.655	0.94
293_I	484_I	0.655	0.94
415_V	420_K	0.651	0.93
82_T	109_N	0.651	0.93
449_V	499_G	0.648	0.93
253_A	296_I	0.648	0.93
155_R	159_K	0.646	0.93
285_M	289_R	0.646	0.93
268_N	301_S	0.644	0.93
331_G	383_T	0.644	0.93
441_E	445_K	0.642	0.93
87_G	91_A	0.639	0.93
404_E	409_A	0.639	0.93
90_M	96_A	0.637	0.93
293_I	296_I	0.637	0.93
216_N	219_Y	0.635	0.93
72_T	79_E	0.631	0.92
276_D	283_D	0.630	0.92
372_F	408_A	0.630	0.92
90_M	95_E	0.628	0.92
282_G	286_D	0.627	0.92
287_E	291_I	0.624	0.92
442_Y	446_V	0.624	0.92
474_F	501_M	0.623	0.92
242_P	279_Y	0.622	0.92
73_Y	108_L	0.622	0.92
474_F	485_V	0.620	0.92
268_N	327_P	0.620	0.92
383_T	387_Y	0.619	0.92
247_Q	254_S	0.618	0.92
331_G	345_R	0.618	0.92
245_I	284_L	0.618	0.92
370_V	399_I	0.617	0.91
394_S	435_S	0.615	0.91
281_L	298_F	0.613	0.91
281_L	285_M	0.613	0.91
77_M	80_H	0.612	0.91
377_D	423_R	0.611	0.91
487_V	490_Q	0.610	0.91
334_E	376_T	0.610	0.91
242_P	283_D	0.609	0.91
68_F	89_F	0.607	0.91
440_K	491_Q	0.607	0.91
418_R	422_E	0.606	0.91
380_F	387_Y	0.606	0.91
399_I	420_K	0.605	0.91
201_E	204_P	0.604	0.91
69_Y	98_N	0.603	0.91
108_L	121_V	0.603	0.91
253_A	319_N	0.603	0.91
99_S	131_L	0.603	0.91
480_A	501_M	0.602	0.90
439_M	492_A	0.600	0.90
464_G	474_F	0.598	0.90
446_V	499_G	0.598	0.90
334_E	374_N	0.598	0.90
112_A	149_E	0.597	0.90
215_V	240_R	0.597	0.90
456_K	460_D	0.597	0.90
421_K	424_L	0.597	0.90
253_A	257_Y	0.596	0.90
157_L	166_I	0.595	0.90
387_Y	430_L	0.594	0.90
199_V	202_N	0.591	0.90
120_K	123_G	0.590	0.90
334_E	337_K	0.589	0.90
129_K	132_K	0.588	0.89
381_E	422_E	0.588	0.89
195_K	198_D	0.587	0.89
154_N	157_L	0.586	0.89
387_Y	391_E	0.584	0.89
288_L	291_I	0.584	0.89
462_L	481_I	0.584	0.89
132_K	137_D	0.583	0.89
285_M	288_L	0.582	0.89
183_Y	186_K	0.582	0.89
175_L	179_L	0.581	0.89
397_T	427_L	0.580	0.89
160_H	163_V	0.580	0.89
316_K	319_N	0.577	0.89
397_T	431_V	0.577	0.89
260_I	288_L	0.576	0.88
174_R	191_E	0.576	0.88
331_G	386_L	0.575	0.88
490_Q	498_D	0.574	0.88
71_R	108_L	0.571	0.88
400_Y	411_M	0.571	0.88
478_K	483_K	0.570	0.88
200_I	204_P	0.566	0.88
131_L	135_N	0.566	0.88
308_D	351_L	0.565	0.88
207_R	255_E	0.564	0.87
274_F	279_Y	0.564	0.87
368_I	383_T	0.563	0.87
123_G	126_G	0.563	0.87
328_V	392_F	0.562	0.87
69_Y	99_S	0.562	0.87
461_I	498_D	0.562	0.87
462_L	477_P	0.562	0.87
333_S	350_E	0.561	0.87
176_P	179_L	0.561	0.87
201_E	244_D	0.559	0.87
388_R	391_E	0.559	0.87
227_Y	340_A	0.557	0.87
88_I	91_A	0.556	0.87
209_G	257_Y	0.556	0.87
200_I	203_L	0.555	0.87
217_I	284_L	0.554	0.86
202_N	244_D	0.554	0.86
132_K	138_L	0.553	0.86
223_K	342_K	0.552	0.86
116_N	120_K	0.552	0.86
268_N	305_D	0.551	0.86
422_E	425_Q	0.550	0.86
217_I	267_V	0.548	0.86
443_E	446_V	0.547	0.86
438_K	470_K	0.547	0.86
439_M	497_L	0.546	0.86
132_K	162_F	0.545	0.86
223_K	233_T	0.545	0.86
110_T	125_L	0.545	0.86
470_K	497_L	0.545	0.86
172_I	176_P	0.544	0.86
131_L	137_D	0.544	0.86
262_L	288_L	0.543	0.85
139_I	164_D	0.542	0.85
242_P	284_L	0.542	0.85
248_E	252_L	0.542	0.85
217_I	245_I	0.541	0.85
300_T	323_H	0.541	0.85
223_K	304_R	0.539	0.85
97_T	100_V	0.538	0.85
223_K	340_A	0.537	0.85
353_R	390_V	0.535	0.85
443_E	489_I	0.535	0.85
132_K	140_L	0.535	0.85
226_T	304_R	0.533	0.84
107_L	165_M	0.531	0.84
285_M	296_I	0.531	0.84
126_G	160_H	0.531	0.84
326_L	340_A	0.530	0.84
246_I	284_L	0.529	0.84
269_A	326_L	0.528	0.84
301_S	324_I	0.527	0.84
463_A	471_L	0.526	0.84
122_F	126_G	0.526	0.84
298_F	301_S	0.525	0.83
87_G	204_P	0.525	0.83
428_N	435_S	0.525	0.83
384_L	422_E	0.524	0.83
118_E	149_E	0.524	0.83
211_I	450_L	0.523	0.83
492_A	497_L	0.523	0.83
199_V	203_L	0.523	0.83
462_L	480_A	0.523	0.83
242_P	277_M	0.523	0.83
361_N	468_K	0.522	0.83
454_E	460_D	0.522	0.83
343_Y	348_Y	0.516	0.82
272_K	277_M	0.515	0.82
222_D	237_E	0.515	0.82
300_T	328_V	0.514	0.82
269_A	327_P	0.514	0.82
435_S	494_T	0.514	0.82
180_S	183_Y	0.514	0.82
377_D	384_L	0.513	0.82
313_V	316_K	0.513	0.82
266_N	281_L	0.513	0.82
211_I	257_Y	0.511	0.82
190_V	193_W	0.511	0.82
454_E	476_G	0.510	0.82
312_E	354_K	0.510	0.82
419_V	423_R	0.510	0.82
464_G	484_I	0.510	0.82
301_S	326_L	0.510	0.82
309_R	313_V	0.509	0.82
267_V	299_T	0.508	0.81
291_I	296_I	0.508	0.81
84_V	88_I	0.506	0.81
212_K	452_E	0.506	0.81
325_H	367_D	0.505	0.81
402_P	406_T	0.505	0.81
425_Q	428_N	0.504	0.81
167_F	175_L	0.504	0.81
464_G	485_V	0.503	0.81
407_P	411_M	0.502	0.81
223_K	305_D	0.502	0.81
68_F	82_T	0.502	0.81
224_F	407_P	0.501	0.81
473_N	498_D	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4jc0A	1	0.8212	100	0.419	Contact Map
2qgqA	1	0.5226	100	0.602	Contact Map
1oltA	1	0.6424	100	0.796	Contact Map
4u0oB	1	0.5206	99.9	0.843	Contact Map
4wcxA	1	0.666	99.9	0.861	Contact Map
2yx0A	1	0.5776	99.9	0.862	Contact Map
3iixA	1	0.6149	99.9	0.868	Contact Map
2z2uA	1	0.4951	99.8	0.872	Contact Map
3t7vA	1	0.6228	99.8	0.872	Contact Map
3c8fA	1	0.4519	99.8	0.872	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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