GREMLIN Database
RNJ2 - Ribonuclease J2
UniProt: O31760 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 555 (544)
Sequences: 3097 (1872)
Seq/√Len: 80.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_D68_K5.9941.00
72_L104_L5.1131.00
70_I83_V4.6751.00
61_I89_K4.6531.00
220_L227_V4.5231.00
97_T148_V4.2441.00
153_K188_S3.9101.00
291_K323_E3.6501.00
27_I36_V3.4851.00
192_A387_I3.3791.00
289_Y294_V3.3581.00
151_S158_S3.2861.00
217_S248_Q3.1671.00
9_V159_I3.1291.00
322_I354_A2.9841.00
127_V134_K2.8081.00
138_F149_G2.8071.00
96_G104_L2.7871.00
416_I422_V2.7841.00
254_A286_V2.7791.00
246_A295_A2.7511.00
387_I422_V2.7331.00
36_V152_F2.6871.00
129_T134_K2.6771.00
153_K158_S2.6521.00
35_V67_V2.6281.00
63_R66_R2.5911.00
400_S404_E2.5741.00
10_R28_E2.5241.00
414_F422_V2.5141.00
32_D132_S2.4841.00
281_I289_Y2.4711.00
404_E410_R2.4461.00
35_V60_L2.4001.00
36_V73_T2.3991.00
386_L399_H2.3751.00
60_L67_V2.3521.00
193_L381_L2.3521.00
72_L100_T2.3391.00
229_I242_V2.3271.00
195_S378_I2.3251.00
255_V264_L2.3041.00
33_I60_L2.3001.00
184_K187_N2.2911.00
372_E375_K2.2621.00
33_I67_V2.2561.00
206_T370_S2.2551.00
31_S66_R2.2521.00
123_H126_S2.2371.00
70_I92_V2.2361.00
162_T377_M2.2301.00
243_I253_I2.2021.00
71_F150_V2.2001.00
96_G101_L2.1911.00
11_I192_A2.1831.00
187_N382_K2.1721.00
400_S413_I2.1391.00
134_K153_K2.1201.00
72_L96_G2.0961.00
313_A348_L2.0931.00
57_I86_L2.0641.00
374_L402_I2.0601.00
247_A276_D2.0511.00
151_S185_I2.0501.00
101_L119_L2.0141.00
275_A280_F1.9901.00
136_S181_E1.9711.00
137_F150_V1.9581.00
36_V150_V1.9491.00
160_V381_L1.9461.00
12_I421_V1.9121.00
351_R417_E1.8951.00
83_V94_V1.8221.00
386_L403_A1.8201.00
225_N327_T1.8181.00
421_V435_V1.8091.00
24_L35_V1.7991.00
504_A534_L1.7561.00
480_L483_G1.7431.00
474_D477_K1.7421.00
220_L295_A1.7381.00
401_K404_E1.7341.00
34_F71_F1.7301.00
217_S249_N1.7281.00
71_F135_V1.7231.00
219_A329_V1.7221.00
29_I155_S1.7211.00
242_V295_A1.7191.00
140_T147_S1.7141.00
195_S399_H1.6841.00
182_I381_L1.6831.00
378_I408_M1.6751.00
32_D66_R1.6741.00
503_Q541_K1.6711.00
70_I86_L1.6591.00
282_S285_D1.6531.00
371_Q402_I1.6481.00
425_R428_N1.6441.00
511_I533_A1.6321.00
386_L408_M1.6241.00
421_V433_D1.6181.00
469_V534_L1.6051.00
167_F177_C1.5971.00
250_G293_E1.5921.00
122_I137_F1.5911.00
467_L538_L1.5751.00
195_S386_L1.5741.00
200_A374_L1.5661.00
135_V150_V1.5641.00
8_N423_E1.5551.00
28_E66_R1.5480.99
290_P293_E1.5460.99
191_L384_K1.5440.99
247_A279_L1.5420.99
98_K121_E1.5340.99
71_F130_F1.5340.99
181_E184_K1.5300.99
61_I64_A1.5200.99
34_F133_T1.5180.99
17_V416_I1.5180.99
88_N111_Y1.5070.99
285_D288_K1.5050.99
265_Q269_K1.5000.99
190_V381_L1.4820.99
165_F195_S1.4780.99
200_A398_A1.4740.99
421_V432_G1.4700.99
203_P371_Q1.4700.99
27_I152_F1.4680.99
160_V193_L1.4670.99
400_S415_L1.4630.99
268_R277_D1.4530.99
507_L511_I1.4440.99
179_I183_A1.4410.99
286_V294_V1.4180.99
312_M320_L1.4180.99
255_V280_F1.3940.99
213_S241_Q1.3830.99
378_I386_L1.3830.99
26_V33_I1.3750.99
69_A130_F1.3710.99
398_A401_K1.3680.99
36_V161_C1.3680.99
379_N406_T1.3650.99
34_F68_K1.3600.99
245_A249_N1.3550.99
169_Q379_N1.3530.99
509_R513_T1.3470.99
286_V289_Y1.3470.99
34_F135_V1.3460.99
253_I279_L1.3380.98
57_I90_L1.3370.98
404_E413_I1.3330.98
218_D222_N1.3320.98
102_A270_L1.3240.98
101_L121_E1.3230.98
530_M533_A1.3200.98
87_L108_L1.3150.98
14_L26_V1.3120.98
458_R465_G1.3110.98
472_T482_S1.3010.98
106_E266_L1.2980.98
79_N390_N1.2970.98
154_T157_G1.2920.98
244_H274_E1.2920.98
224_Q292_R1.2890.98
160_V185_I1.2820.98
11_I194_L1.2810.98
502_V505_T1.2790.98
409_K412_D1.2780.98
177_C182_I1.2760.98
97_T100_T1.2760.98
236_I263_V1.2720.98
28_E59_Y1.2700.98
457_D489_R1.2650.98
122_I148_V1.2630.98
219_A357_I1.2630.98
504_A538_L1.2590.98
511_I529_A1.2560.98
17_V418_K1.2440.98
136_S153_K1.2410.98
76_H368_H1.2380.97
200_A402_I1.2320.97
158_S188_S1.2290.97
58_S61_I1.2260.97
289_Y293_E1.2230.97
472_T553_M1.2210.97
232_F390_N1.2150.97
140_T182_I1.2150.97
34_F130_F1.2130.97
281_I294_V1.2070.97
32_D131_E1.2040.97
446_G449_D1.2030.97
74_H142_H1.2000.97
197_S399_H1.1990.97
378_I399_H1.1960.97
124_S148_V1.1960.97
34_F69_A1.1920.97
444_G447_V1.1920.97
198_A390_N1.1900.97
15_G19_E1.1900.97
508_V530_M1.1790.97
275_A278_E1.1730.97
206_T365_V1.1730.97
240_Q244_H1.1650.96
173_L237_N1.1610.96
322_I328_V1.1560.96
192_A424_F1.1540.96
138_F181_E1.1500.96
74_H79_N1.1480.96
130_F133_T1.1450.96
72_L83_V1.1430.96
47_M53_V1.1430.96
268_R278_E1.1320.96
138_F160_V1.1310.96
83_V92_V1.1300.96
420_D431_I1.1290.96
75_G103_L1.1260.96
232_F337_G1.1260.96
416_I431_I1.1180.95
9_V29_I1.1120.95
211_A214_G1.1000.95
30_D132_S1.1000.95
139_R146_D1.0980.95
102_A269_K1.0930.95
205_Y372_E1.0920.95
470_V551_I1.0850.95
106_E262_S1.0830.95
384_K412_D1.0800.94
223_S327_T1.0780.94
284_Q319_Q1.0770.94
80_I103_L1.0750.94
76_H142_H1.0740.94
26_V60_L1.0730.94
8_N425_R1.0630.94
334_P342_Y1.0620.94
444_G448_G1.0580.94
135_V152_F1.0470.93
26_V35_V1.0460.93
27_I159_I1.0360.93
128_I135_V1.0330.93
27_I161_C1.0320.93
79_N164_D1.0320.93
307_A330_I1.0320.93
198_A232_F1.0310.93
446_G451_G1.0290.93
471_I512_V1.0290.93
33_I59_Y1.0290.93
486_I504_A1.0270.93
78_E368_H1.0250.93
506_E509_R1.0240.93
74_H368_H1.0200.93
515_A520_N1.0180.93
307_A310_T1.0170.92
528_Q532_D1.0140.92
333_T342_Y1.0120.92
58_S436_P1.0110.92
147_S163_G1.0100.92
500_L538_L1.0090.92
194_L389_V1.0020.92
58_S62_E0.9960.92
180_G183_A0.9920.92
100_T240_Q0.9920.92
508_V512_V0.9910.91
500_L542_T0.9900.91
346_V356_V0.9880.91
491_F542_T0.9840.91
96_G119_L0.9830.91
335_I338_Q0.9770.91
299_A304_E0.9760.91
213_S245_A0.9720.91
528_Q531_R0.9720.91
28_E33_I0.9680.90
501_I504_A0.9680.90
165_F374_L0.9670.90
338_Q342_Y0.9660.90
515_A526_L0.9640.90
136_S151_S0.9600.90
29_I132_S0.9590.90
12_I435_V0.9530.90
140_T177_C0.9520.90
377_M381_L0.9500.90
385_Y414_F0.9490.90
516_T520_N0.9480.90
124_S178_D0.9470.90
179_I182_I0.9450.89
11_I387_I0.9440.89
25_Y389_V0.9440.89
534_L548_I0.9440.89
153_K185_I0.9420.89
64_A67_V0.9410.89
86_L90_L0.9390.89
184_K188_S0.9330.89
507_L530_M0.9320.89
40_L52_V0.9320.89
127_V136_S0.9320.89
480_L516_T0.9310.89
11_I25_Y0.9280.89
183_A380_L0.9240.88
167_F179_I0.9220.88
167_F377_M0.9210.88
10_R421_V0.9210.88
129_T132_S0.9190.88
73_T161_C0.9190.88
149_G160_V0.9140.88
10_R423_E0.9130.88
239_I264_L0.9120.88
57_I60_L0.9080.87
17_V25_Y0.9050.87
78_E198_A0.9050.87
35_V86_L0.9040.87
525_T529_A0.9040.87
508_V511_I0.9000.87
217_S221_Y0.8990.87
13_A25_Y0.8960.87
238_R367_G0.8950.87
485_E495_R0.8890.86
74_H78_E0.8870.86
507_L537_F0.8870.86
245_A248_Q0.8820.86
20_I198_A0.8810.86
396_Q415_L0.8780.86
435_V438_G0.8760.86
397_K400_S0.8740.85
503_Q537_F0.8740.85
264_L297_I0.8710.85
71_F128_I0.8660.85
507_L533_A0.8660.85
468_I485_E0.8660.85
492_V500_L0.8660.85
105_R269_K0.8640.85
193_L378_I0.8640.85
54_I442_I0.8580.84
25_Y36_V0.8580.84
75_G144_I0.8550.84
478_K516_T0.8540.84
9_V155_S0.8530.84
108_L117_T0.8510.84
19_E418_K0.8460.83
291_K294_V0.8450.83
348_L352_A0.8450.83
529_A533_A0.8450.83
204_G372_E0.8450.83
142_H368_H0.8430.83
492_V542_T0.8430.83
140_T149_G0.8410.83
471_I530_M0.8390.83
22_K334_P0.8370.83
347_D392_E0.8360.83
216_I220_L0.8340.83
22_K333_T0.8330.83
223_S227_V0.8310.82
227_V329_V0.8300.82
258_K311_R0.8300.82
87_L94_V0.8270.82
113_H117_T0.8240.82
12_I59_Y0.8240.82
64_A91_S0.8230.82
302_Q338_Q0.8210.82
385_Y424_F0.8210.82
163_G198_A0.8200.82
70_I94_V0.8190.81
300_G304_E0.8190.81
97_T146_D0.8170.81
138_F182_I0.8110.81
79_N198_A0.8110.81
444_G461_L0.8100.81
535_N545_K0.8080.81
364_H367_G0.8070.80
327_T355_Q0.8070.80
77_D107_K0.8070.80
9_V156_L0.8040.80
38_A57_I0.8040.80
513_T517_E0.8020.80
12_I26_V0.8010.80
511_I530_M0.7990.80
72_L101_L0.7990.80
408_M412_D0.7970.80
315_K352_A0.7970.80
201_E394_R0.7960.80
33_I66_R0.7950.79
227_V295_A0.7940.79
19_E22_K0.7900.79
302_Q335_I0.7890.79
217_S245_A0.7880.79
310_T314_N0.7830.78
138_F185_I0.7830.78
162_T193_L0.7820.78
310_T345_T0.7810.78
449_D453_I0.7790.78
298_T312_M0.7780.78
385_Y429_V0.7780.78
27_I133_T0.7780.78
103_L263_V0.7770.78
219_A327_T0.7740.78
189_G384_K0.7730.78
9_V27_I0.7710.77
195_S408_M0.7710.77
122_I128_I0.7690.77
302_Q364_H0.7690.77
532_D539_Y0.7690.77
79_N142_H0.7680.77
376_L379_N0.7650.77
417_E420_D0.7640.77
470_V553_M0.7600.76
345_T349_L0.7590.76
302_Q390_N0.7550.76
348_L351_R0.7550.76
76_H79_N0.7550.76
252_K293_E0.7530.76
537_F541_K0.7530.76
539_Y543_K0.7530.76
125_K181_E0.7490.75
220_L249_N0.7490.75
403_A408_M0.7450.75
507_L510_S0.7440.75
197_S392_E0.7440.75
157_G191_L0.7430.75
420_D434_K0.7410.75
68_K132_S0.7380.74
286_V320_L0.7380.74
193_L386_L0.7370.74
159_I192_A0.7360.74
214_G218_D0.7350.74
343_S347_D0.7340.74
105_R121_E0.7330.74
164_D390_N0.7310.74
242_V297_I0.7310.74
100_T148_V0.7310.74
106_E109_K0.7300.73
158_S185_I0.7280.73
78_E142_H0.7280.73
550_P553_M0.7270.73
453_I456_R0.7250.73
327_T357_I0.7240.73
387_I416_I0.7240.73
246_A253_I0.7220.73
204_G370_S0.7220.73
205_Y373_E0.7200.72
275_A279_L0.7200.72
160_V190_V0.7200.72
34_F152_F0.7190.72
527_K531_R0.7180.72
493_Y501_I0.7180.72
24_L38_A0.7170.72
69_A95_Y0.7170.72
315_K321_N0.7150.72
396_Q399_H0.7140.72
502_V507_L0.7130.72
506_E510_S0.7130.72
191_L385_Y0.7130.72
67_V90_L0.7100.71
256_A320_L0.7090.71
474_D481_V0.7080.71
448_G451_G0.7080.71
350_A356_V0.7070.71
142_H238_R0.7060.71
140_T377_M0.7050.71
302_Q337_G0.7050.71
255_V297_I0.7030.71
78_E366_S0.7020.70
256_A312_M0.7010.70
139_R175_Q0.7010.70
322_I352_A0.7010.70
202_R370_S0.6990.70
483_G495_R0.6980.70
86_L92_V0.6980.70
179_I377_M0.6960.70
233_A390_N0.6950.70
532_D536_Q0.6930.70
76_H366_S0.6920.69
71_F131_E0.6900.69
315_K329_V0.6900.69
33_I63_R0.6890.69
259_N302_Q0.6880.69
198_A337_G0.6880.69
198_A368_H0.6870.69
100_T339_E0.6860.69
57_I61_I0.6860.69
222_N469_V0.6850.69
453_I549_I0.6840.69
488_T493_Y0.6840.69
241_Q245_A0.6810.68
38_A70_I0.6800.68
105_R109_K0.6800.68
79_N232_F0.6800.68
532_D547_M0.6790.68
453_I457_D0.6790.68
32_D69_A0.6780.68
527_K551_I0.6780.68
273_I276_D0.6760.68
502_V514_E0.6760.68
423_E430_K0.6750.67
443_D454_V0.6750.67
297_I394_R0.6730.67
25_Y194_L0.6720.67
209_E303_G0.6710.67
228_I312_M0.6700.67
442_I448_G0.6690.67
488_T491_F0.6690.67
24_L57_I0.6680.67
355_Q401_K0.6680.67
68_K95_Y0.6680.67
531_R550_P0.6650.66
59_Y63_R0.6650.66
503_Q506_E0.6650.66
209_E364_H0.6650.66
97_T122_I0.6640.66
159_I194_L0.6640.66
286_V296_I0.6640.66
493_Y497_S0.6630.66
491_F544_R0.6620.66
530_M534_L0.6620.66
423_E432_G0.6610.66
247_A253_I0.6600.66
247_A250_G0.6600.66
205_Y370_S0.6600.66
474_D484_P0.6590.66
513_T519_S0.6590.66
312_M317_H0.6590.66
513_T516_T0.6590.66
147_S369_G0.6590.66
15_G21_G0.6580.66
539_Y542_T0.6570.65
493_Y539_Y0.6570.65
254_A320_L0.6550.65
235_N367_G0.6530.65
195_S374_L0.6530.65
74_H366_S0.6500.65
244_H247_A0.6460.64
467_L504_A0.6460.64
375_K402_I0.6460.64
195_S377_M0.6450.64
110_Q113_H0.6450.64
544_R550_P0.6440.64
54_I447_V0.6430.64
446_G450_I0.6430.64
495_R532_D0.6430.64
338_Q390_N0.6420.64
209_E367_G0.6420.64
144_I307_A0.6410.64
124_S139_R0.6410.64
335_I390_N0.6400.63
151_S191_L0.6380.63
78_E390_N0.6380.63
424_F429_V0.6380.63
504_A508_V0.6380.63
228_I298_T0.6370.63
209_E302_Q0.6360.63
162_T198_A0.6360.63
185_I381_L0.6350.63
505_T509_R0.6350.63
508_V533_A0.6340.63
522_E525_T0.6320.62
514_E525_T0.6310.62
314_N348_L0.6300.62
445_L449_D0.6290.62
281_I285_D0.6290.62
489_R549_I0.6280.62
137_F148_V0.6280.62
122_I135_V0.6260.62
109_K112_G0.6260.62
523_W527_K0.6240.61
94_V104_L0.6230.61
399_H408_M0.6230.61
216_I245_A0.6220.61
501_I505_T0.6200.61
471_I481_V0.6200.61
399_H403_A0.6190.61
224_Q327_T0.6190.61
11_I27_I0.6170.61
535_N548_I0.6150.60
95_Y120_R0.6150.60
347_D353_G0.6140.60
243_I247_A0.6130.60
322_I349_L0.6130.60
219_A363_V0.6120.60
534_L538_L0.6110.60
507_L513_T0.6110.60
8_N26_V0.6110.60
55_P82_G0.6110.60
50_I529_A0.6110.60
536_Q539_Y0.6110.60
42_H259_N0.6100.60
183_A186_G0.6100.60
536_Q540_E0.6080.59
195_S381_L0.6070.59
414_F429_V0.6070.59
156_L427_Q0.6070.59
321_N536_Q0.6070.59
38_A86_L0.6060.59
199_N390_N0.6040.59
481_V484_P0.6040.59
417_E434_K0.6030.59
12_I33_I0.6030.59
442_I447_V0.6020.59
38_A82_G0.6000.58
488_T492_V0.6000.58
433_D436_P0.5990.58
412_D499_G0.5980.58
231_V297_I0.5980.58
495_R498_E0.5970.58
468_I551_I0.5960.58
123_H128_I0.5920.57
381_L386_L0.5910.57
527_K549_I0.5910.57
372_E376_L0.5900.57
498_E503_Q0.5900.57
14_L435_V0.5890.57
538_L542_T0.5890.57
371_Q398_A0.5880.57
196_D368_H0.5880.57
446_G455_L0.5880.57
515_A529_A0.5870.57
486_I505_T0.5850.57
261_Q282_S0.5840.56
443_D456_R0.5840.56
517_E520_N0.5830.56
483_G509_R0.5830.56
112_G180_G0.5820.56
181_E530_M0.5820.56
42_H302_Q0.5810.56
205_Y376_L0.5810.56
200_A413_I0.5800.56
375_K406_T0.5800.56
512_V520_N0.5780.56
523_W549_I0.5780.56
384_K426_G0.5770.56
351_R393_Y0.5770.56
151_S160_V0.5770.56
28_E31_S0.5770.56
474_D482_S0.5770.56
235_N241_Q0.5770.56
486_I501_I0.5750.55
336_P364_H0.5750.55
461_L464_D0.5740.55
10_R66_R0.5740.55
80_I104_L0.5740.55
527_K542_T0.5740.55
215_E218_D0.5740.55
78_E163_G0.5740.55
35_V70_I0.5740.55
504_A539_Y0.5730.55
470_V485_E0.5730.55
268_R275_A0.5720.55
16_G21_G0.5720.55
510_S524_S0.5720.55
484_P550_P0.5720.55
101_L105_R0.5710.55
227_V327_T0.5710.55
198_A303_G0.5710.55
171_P209_E0.5710.55
83_V174_N0.5700.55
87_L91_S0.5690.54
109_K315_K0.5670.54
11_I429_V0.5670.54
40_L53_V0.5660.54
186_G190_V0.5650.54
19_E226_R0.5650.54
303_G390_N0.5650.54
247_A274_E0.5650.54
67_V70_I0.5650.54
538_L541_K0.5650.54
432_G436_P0.5640.54
384_K428_N0.5630.54
524_S527_K0.5620.54
493_Y542_T0.5620.54
387_I424_F0.5610.53
198_A302_Q0.5610.53
259_N364_H0.5610.53
164_D232_F0.5590.53
215_E361_K0.5590.53
512_V518_T0.5590.53
37_D142_H0.5590.53
87_L92_V0.5580.53
453_I553_M0.5580.53
189_G251_R0.5570.53
343_S346_V0.5560.53
99_L270_L0.5560.53
454_V457_D0.5560.53
9_V191_L0.5560.53
482_S509_R0.5550.53
42_H78_E0.5550.53
233_A303_G0.5540.53
464_D538_L0.5540.53
77_D390_N0.5540.53
93_P120_R0.5530.52
225_N325_G0.5520.52
169_Q376_L0.5520.52
186_G380_L0.5520.52
482_S553_M0.5510.52
304_E390_N0.5490.52
259_N338_Q0.5490.52
198_A304_E0.5480.52
231_V260_L0.5480.52
470_V550_P0.5480.52
201_E398_A0.5480.52
485_E498_E0.5480.52
18_G417_E0.5470.52
481_V510_S0.5470.52
21_G390_N0.5460.52
513_T520_N0.5460.52
474_D511_I0.5460.52
346_V349_L0.5450.51
161_C389_V0.5440.51
76_H196_D0.5440.51
385_Y427_Q0.5440.51
20_I42_H0.5440.51
424_F428_N0.5440.51
526_L530_M0.5430.51
443_D458_R0.5430.51
376_L380_L0.5420.51
98_K123_H0.5420.51
312_M328_V0.5410.51
72_L82_G0.5410.51
87_L90_L0.5400.51
487_I491_F0.5400.51
42_H77_D0.5390.51
99_L146_D0.5380.50
218_D221_Y0.5380.50
142_H164_D0.5380.50
536_Q553_M0.5360.50
108_L113_H0.5360.50
525_T540_E0.5350.50
254_A281_I0.5350.50
191_L427_Q0.5340.50
100_T122_I0.5330.50
454_V468_I0.5330.50
511_I514_E0.5310.50
169_Q205_Y0.5310.50
492_V495_R0.5310.50
140_T160_V0.5310.50
497_S501_I0.5300.49
336_P367_G0.5300.49
180_G187_N0.5300.49
452_N468_I0.5300.49
226_R291_K0.5300.49
527_K552_I0.5290.49
505_T533_A0.5290.49
128_I137_F0.5290.49
232_F303_G0.5280.49
211_A362_R0.5280.49
532_D542_T0.5280.49
485_E505_T0.5270.49
534_L544_R0.5260.49
74_H164_D0.5260.49
102_A266_L0.5260.49
448_G455_L0.5260.49
166_K209_E0.5250.49
501_I530_M0.5250.49
475_K478_K0.5250.49
476_Q516_T0.5250.49
232_F302_Q0.5240.49
296_I308_A0.5240.49
441_L455_L0.5240.49
84_F240_Q0.5240.49
224_Q227_V0.5230.49
522_E531_R0.5230.49
245_A540_E0.5230.49
539_Y552_I0.5230.49
347_D351_R0.5230.49
539_Y545_K0.5220.48
91_S117_T0.5210.48
510_S514_E0.5200.48
61_I90_L0.5200.48
480_L509_R0.5190.48
27_I34_F0.5190.48
453_I470_V0.5190.48
332_S337_G0.5190.48
529_A545_K0.5170.48
8_N512_V0.5160.48
168_D209_E0.5160.48
222_N355_Q0.5160.48
527_K547_M0.5150.47
429_V433_D0.5150.47
27_I156_L0.5140.47
316_A525_T0.5130.47
145_P263_V0.5130.47
182_I185_I0.5130.47
135_V153_K0.5130.47
385_Y428_N0.5120.47
215_E219_A0.5120.47
209_E233_A0.5120.47
470_V479_H0.5120.47
228_I322_I0.5120.47
141_I177_C0.5110.47
54_I446_G0.5110.47
78_E232_F0.5100.47
274_E277_D0.5090.47
449_D454_V0.5080.47
369_G373_E0.5080.47
232_F364_H0.5070.46
518_T536_Q0.5070.46
328_V512_V0.5070.46
512_V516_T0.5070.46
471_I480_L0.5070.46
21_G232_F0.5070.46
488_T501_I0.5070.46
520_N525_T0.5060.46
163_G368_H0.5060.46
229_I295_A0.5060.46
27_I194_L0.5060.46
535_N544_R0.5040.46
76_H198_A0.5040.46
528_Q535_N0.5040.46
344_K348_L0.5030.46
330_I345_T0.5030.46
542_T545_K0.5030.46
160_V182_I0.5030.46
451_G491_F0.5020.46
524_S528_Q0.5020.46
329_V549_I0.5010.46
166_K367_G0.5000.46
60_L64_A0.5000.46
79_N338_Q0.5000.46
151_S188_S0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zq4A 3 0.9892 100 0.217 Contact Map
3bk2A 2 0.9748 100 0.24 Contact Map
2az4A 1 0.6937 100 0.507 Contact Map
3iekA 3 0.6937 100 0.541 Contact Map
2ycbA 2 0.7279 100 0.552 Contact Map
2i7tA 1 0.6721 100 0.552 Contact Map
2xr1A 2 0.7243 100 0.557 Contact Map
3af5A 1 0.7297 100 0.56 Contact Map
2i7xA 1 0.6991 100 0.596 Contact Map
4b87A 1 0.5802 100 0.638 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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