RNJ2 - BACSU - GREMLIN Contacts

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RNJ2 - Ribonuclease J2

UniProt:	O31760	Sequences: MKKKNTENVRIIALGGVGEIGKNLYVIEIDSDIFVVDAGLMHPENEMLGIDVVIPDISYLIERADRVKAIFLTHGHDENIGGVFYLLNKLSVPVYGTKLTLALLREKLKQYGHNRKTDLREIHSKSVITFESTKVSFFRTIHSIPDSVGVSFKTSLGSIVCTGDFKFDQTPALNQTCDIGEIAKIGNSGVLALLSDSANAERPGYTPSEAAVSGEISDALYNSQNRVIIAVFASNINRIQQVIHAAAQNGRKIAVAGKNLQSVLQLARKLGYIEADDELFISVQDVKKYPKREVAIITAGSQGEPLAALTRMANKAHKQLNIEEGDTVVIASTPIPGQELIYSKTVDLLARAGAQVIFAQKRVHVSGHGSQEELKLMINLLKPKYLIPVNGEYRMQKAHSKIAEETGMKRSDIFLIEKGDVVEFRGQNVKIGDKVPYGNILIDGLGVGDIGNIVLRDRRLLSQDGILIVVITLDKQKKHLVSGPEIITRGFVYVRESEGLIVQATELVRSIVTEATETSNVEWSTLKQAMRDALNQFLYEKTKRKPMIIPIIMEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	555 (544)
Sequences:	3097 (1872)
Seq/√Len:	80.3

BACSU - RNJ2 RNJ1
HALSA - Q9HS54 RNJ
SULSO - Q7LYL5 Q980D0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
32_D	68_K	5.994	1.00
72_L	104_L	5.113	1.00
70_I	83_V	4.675	1.00
61_I	89_K	4.653	1.00
220_L	227_V	4.523	1.00
97_T	148_V	4.244	1.00
153_K	188_S	3.910	1.00
291_K	323_E	3.650	1.00
27_I	36_V	3.485	1.00
192_A	387_I	3.379	1.00
289_Y	294_V	3.358	1.00
151_S	158_S	3.286	1.00
217_S	248_Q	3.167	1.00
9_V	159_I	3.129	1.00
322_I	354_A	2.984	1.00
127_V	134_K	2.808	1.00
138_F	149_G	2.807	1.00
96_G	104_L	2.787	1.00
416_I	422_V	2.784	1.00
254_A	286_V	2.779	1.00
246_A	295_A	2.751	1.00
387_I	422_V	2.733	1.00
36_V	152_F	2.687	1.00
129_T	134_K	2.677	1.00
153_K	158_S	2.652	1.00
35_V	67_V	2.628	1.00
63_R	66_R	2.591	1.00
400_S	404_E	2.574	1.00
10_R	28_E	2.524	1.00
414_F	422_V	2.514	1.00
32_D	132_S	2.484	1.00
281_I	289_Y	2.471	1.00
404_E	410_R	2.446	1.00
35_V	60_L	2.400	1.00
36_V	73_T	2.399	1.00
386_L	399_H	2.375	1.00
60_L	67_V	2.352	1.00
193_L	381_L	2.352	1.00
72_L	100_T	2.339	1.00
229_I	242_V	2.327	1.00
195_S	378_I	2.325	1.00
255_V	264_L	2.304	1.00
33_I	60_L	2.300	1.00
184_K	187_N	2.291	1.00
372_E	375_K	2.262	1.00
33_I	67_V	2.256	1.00
206_T	370_S	2.255	1.00
31_S	66_R	2.252	1.00
123_H	126_S	2.237	1.00
70_I	92_V	2.236	1.00
162_T	377_M	2.230	1.00
243_I	253_I	2.202	1.00
71_F	150_V	2.200	1.00
96_G	101_L	2.191	1.00
11_I	192_A	2.183	1.00
187_N	382_K	2.172	1.00
400_S	413_I	2.139	1.00
134_K	153_K	2.120	1.00
72_L	96_G	2.096	1.00
313_A	348_L	2.093	1.00
57_I	86_L	2.064	1.00
374_L	402_I	2.060	1.00
247_A	276_D	2.051	1.00
151_S	185_I	2.050	1.00
101_L	119_L	2.014	1.00
275_A	280_F	1.990	1.00
136_S	181_E	1.971	1.00
137_F	150_V	1.958	1.00
36_V	150_V	1.949	1.00
160_V	381_L	1.946	1.00
12_I	421_V	1.912	1.00
351_R	417_E	1.895	1.00
83_V	94_V	1.822	1.00
386_L	403_A	1.820	1.00
225_N	327_T	1.818	1.00
421_V	435_V	1.809	1.00
24_L	35_V	1.799	1.00
504_A	534_L	1.756	1.00
480_L	483_G	1.743	1.00
474_D	477_K	1.742	1.00
220_L	295_A	1.738	1.00
401_K	404_E	1.734	1.00
34_F	71_F	1.730	1.00
217_S	249_N	1.728	1.00
71_F	135_V	1.723	1.00
219_A	329_V	1.722	1.00
29_I	155_S	1.721	1.00
242_V	295_A	1.719	1.00
140_T	147_S	1.714	1.00
195_S	399_H	1.684	1.00
182_I	381_L	1.683	1.00
378_I	408_M	1.675	1.00
32_D	66_R	1.674	1.00
503_Q	541_K	1.671	1.00
70_I	86_L	1.659	1.00
282_S	285_D	1.653	1.00
371_Q	402_I	1.648	1.00
425_R	428_N	1.644	1.00
511_I	533_A	1.632	1.00
386_L	408_M	1.624	1.00
421_V	433_D	1.618	1.00
469_V	534_L	1.605	1.00
167_F	177_C	1.597	1.00
250_G	293_E	1.592	1.00
122_I	137_F	1.591	1.00
467_L	538_L	1.575	1.00
195_S	386_L	1.574	1.00
200_A	374_L	1.566	1.00
135_V	150_V	1.564	1.00
8_N	423_E	1.555	1.00
28_E	66_R	1.548	0.99
290_P	293_E	1.546	0.99
191_L	384_K	1.544	0.99
247_A	279_L	1.542	0.99
98_K	121_E	1.534	0.99
71_F	130_F	1.534	0.99
181_E	184_K	1.530	0.99
61_I	64_A	1.520	0.99
34_F	133_T	1.518	0.99
17_V	416_I	1.518	0.99
88_N	111_Y	1.507	0.99
285_D	288_K	1.505	0.99
265_Q	269_K	1.500	0.99
190_V	381_L	1.482	0.99
165_F	195_S	1.478	0.99
200_A	398_A	1.474	0.99
421_V	432_G	1.470	0.99
203_P	371_Q	1.470	0.99
27_I	152_F	1.468	0.99
160_V	193_L	1.467	0.99
400_S	415_L	1.463	0.99
268_R	277_D	1.453	0.99
507_L	511_I	1.444	0.99
179_I	183_A	1.441	0.99
286_V	294_V	1.418	0.99
312_M	320_L	1.418	0.99
255_V	280_F	1.394	0.99
213_S	241_Q	1.383	0.99
378_I	386_L	1.383	0.99
26_V	33_I	1.375	0.99
69_A	130_F	1.371	0.99
398_A	401_K	1.368	0.99
36_V	161_C	1.368	0.99
379_N	406_T	1.365	0.99
34_F	68_K	1.360	0.99
245_A	249_N	1.355	0.99
169_Q	379_N	1.353	0.99
509_R	513_T	1.347	0.99
286_V	289_Y	1.347	0.99
34_F	135_V	1.346	0.99
253_I	279_L	1.338	0.98
57_I	90_L	1.337	0.98
404_E	413_I	1.333	0.98
218_D	222_N	1.332	0.98
102_A	270_L	1.324	0.98
101_L	121_E	1.323	0.98
530_M	533_A	1.320	0.98
87_L	108_L	1.315	0.98
14_L	26_V	1.312	0.98
458_R	465_G	1.311	0.98
472_T	482_S	1.301	0.98
106_E	266_L	1.298	0.98
79_N	390_N	1.297	0.98
154_T	157_G	1.292	0.98
244_H	274_E	1.292	0.98
224_Q	292_R	1.289	0.98
160_V	185_I	1.282	0.98
11_I	194_L	1.281	0.98
502_V	505_T	1.279	0.98
409_K	412_D	1.278	0.98
177_C	182_I	1.276	0.98
97_T	100_T	1.276	0.98
236_I	263_V	1.272	0.98
28_E	59_Y	1.270	0.98
457_D	489_R	1.265	0.98
122_I	148_V	1.263	0.98
219_A	357_I	1.263	0.98
504_A	538_L	1.259	0.98
511_I	529_A	1.256	0.98
17_V	418_K	1.244	0.98
136_S	153_K	1.241	0.98
76_H	368_H	1.238	0.97
200_A	402_I	1.232	0.97
158_S	188_S	1.229	0.97
58_S	61_I	1.226	0.97
289_Y	293_E	1.223	0.97
472_T	553_M	1.221	0.97
232_F	390_N	1.215	0.97
140_T	182_I	1.215	0.97
34_F	130_F	1.213	0.97
281_I	294_V	1.207	0.97
32_D	131_E	1.204	0.97
446_G	449_D	1.203	0.97
74_H	142_H	1.200	0.97
197_S	399_H	1.199	0.97
378_I	399_H	1.196	0.97
124_S	148_V	1.196	0.97
34_F	69_A	1.192	0.97
444_G	447_V	1.192	0.97
198_A	390_N	1.190	0.97
15_G	19_E	1.190	0.97
508_V	530_M	1.179	0.97
275_A	278_E	1.173	0.97
206_T	365_V	1.173	0.97
240_Q	244_H	1.165	0.96
173_L	237_N	1.161	0.96
322_I	328_V	1.156	0.96
192_A	424_F	1.154	0.96
138_F	181_E	1.150	0.96
74_H	79_N	1.148	0.96
130_F	133_T	1.145	0.96
72_L	83_V	1.143	0.96
47_M	53_V	1.143	0.96
268_R	278_E	1.132	0.96
138_F	160_V	1.131	0.96
83_V	92_V	1.130	0.96
420_D	431_I	1.129	0.96
75_G	103_L	1.126	0.96
232_F	337_G	1.126	0.96
416_I	431_I	1.118	0.95
9_V	29_I	1.112	0.95
211_A	214_G	1.100	0.95
30_D	132_S	1.100	0.95
139_R	146_D	1.098	0.95
102_A	269_K	1.093	0.95
205_Y	372_E	1.092	0.95
470_V	551_I	1.085	0.95
106_E	262_S	1.083	0.95
384_K	412_D	1.080	0.94
223_S	327_T	1.078	0.94
284_Q	319_Q	1.077	0.94
80_I	103_L	1.075	0.94
76_H	142_H	1.074	0.94
26_V	60_L	1.073	0.94
8_N	425_R	1.063	0.94
334_P	342_Y	1.062	0.94
444_G	448_G	1.058	0.94
135_V	152_F	1.047	0.93
26_V	35_V	1.046	0.93
27_I	159_I	1.036	0.93
128_I	135_V	1.033	0.93
27_I	161_C	1.032	0.93
79_N	164_D	1.032	0.93
307_A	330_I	1.032	0.93
198_A	232_F	1.031	0.93
446_G	451_G	1.029	0.93
471_I	512_V	1.029	0.93
33_I	59_Y	1.029	0.93
486_I	504_A	1.027	0.93
78_E	368_H	1.025	0.93
506_E	509_R	1.024	0.93
74_H	368_H	1.020	0.93
515_A	520_N	1.018	0.93
307_A	310_T	1.017	0.92
528_Q	532_D	1.014	0.92
333_T	342_Y	1.012	0.92
58_S	436_P	1.011	0.92
147_S	163_G	1.010	0.92
500_L	538_L	1.009	0.92
194_L	389_V	1.002	0.92
58_S	62_E	0.996	0.92
180_G	183_A	0.992	0.92
100_T	240_Q	0.992	0.92
508_V	512_V	0.991	0.91
500_L	542_T	0.990	0.91
346_V	356_V	0.988	0.91
491_F	542_T	0.984	0.91
96_G	119_L	0.983	0.91
335_I	338_Q	0.977	0.91
299_A	304_E	0.976	0.91
213_S	245_A	0.972	0.91
528_Q	531_R	0.972	0.91
28_E	33_I	0.968	0.90
501_I	504_A	0.968	0.90
165_F	374_L	0.967	0.90
338_Q	342_Y	0.966	0.90
515_A	526_L	0.964	0.90
136_S	151_S	0.960	0.90
29_I	132_S	0.959	0.90
12_I	435_V	0.953	0.90
140_T	177_C	0.952	0.90
377_M	381_L	0.950	0.90
385_Y	414_F	0.949	0.90
516_T	520_N	0.948	0.90
124_S	178_D	0.947	0.90
179_I	182_I	0.945	0.89
11_I	387_I	0.944	0.89
25_Y	389_V	0.944	0.89
534_L	548_I	0.944	0.89
153_K	185_I	0.942	0.89
64_A	67_V	0.941	0.89
86_L	90_L	0.939	0.89
184_K	188_S	0.933	0.89
507_L	530_M	0.932	0.89
40_L	52_V	0.932	0.89
127_V	136_S	0.932	0.89
480_L	516_T	0.931	0.89
11_I	25_Y	0.928	0.89
183_A	380_L	0.924	0.88
167_F	179_I	0.922	0.88
167_F	377_M	0.921	0.88
10_R	421_V	0.921	0.88
129_T	132_S	0.919	0.88
73_T	161_C	0.919	0.88
149_G	160_V	0.914	0.88
10_R	423_E	0.913	0.88
239_I	264_L	0.912	0.88
57_I	60_L	0.908	0.87
17_V	25_Y	0.905	0.87
78_E	198_A	0.905	0.87
35_V	86_L	0.904	0.87
525_T	529_A	0.904	0.87
508_V	511_I	0.900	0.87
217_S	221_Y	0.899	0.87
13_A	25_Y	0.896	0.87
238_R	367_G	0.895	0.87
485_E	495_R	0.889	0.86
74_H	78_E	0.887	0.86
507_L	537_F	0.887	0.86
245_A	248_Q	0.882	0.86
20_I	198_A	0.881	0.86
396_Q	415_L	0.878	0.86
435_V	438_G	0.876	0.86
397_K	400_S	0.874	0.85
503_Q	537_F	0.874	0.85
264_L	297_I	0.871	0.85
71_F	128_I	0.866	0.85
507_L	533_A	0.866	0.85
468_I	485_E	0.866	0.85
492_V	500_L	0.866	0.85
105_R	269_K	0.864	0.85
193_L	378_I	0.864	0.85
54_I	442_I	0.858	0.84
25_Y	36_V	0.858	0.84
75_G	144_I	0.855	0.84
478_K	516_T	0.854	0.84
9_V	155_S	0.853	0.84
108_L	117_T	0.851	0.84
19_E	418_K	0.846	0.83
291_K	294_V	0.845	0.83
348_L	352_A	0.845	0.83
529_A	533_A	0.845	0.83
204_G	372_E	0.845	0.83
142_H	368_H	0.843	0.83
492_V	542_T	0.843	0.83
140_T	149_G	0.841	0.83
471_I	530_M	0.839	0.83
22_K	334_P	0.837	0.83
347_D	392_E	0.836	0.83
216_I	220_L	0.834	0.83
22_K	333_T	0.833	0.83
223_S	227_V	0.831	0.82
227_V	329_V	0.830	0.82
258_K	311_R	0.830	0.82
87_L	94_V	0.827	0.82
113_H	117_T	0.824	0.82
12_I	59_Y	0.824	0.82
64_A	91_S	0.823	0.82
302_Q	338_Q	0.821	0.82
385_Y	424_F	0.821	0.82
163_G	198_A	0.820	0.82
70_I	94_V	0.819	0.81
300_G	304_E	0.819	0.81
97_T	146_D	0.817	0.81
138_F	182_I	0.811	0.81
79_N	198_A	0.811	0.81
444_G	461_L	0.810	0.81
535_N	545_K	0.808	0.81
364_H	367_G	0.807	0.80
327_T	355_Q	0.807	0.80
77_D	107_K	0.807	0.80
9_V	156_L	0.804	0.80
38_A	57_I	0.804	0.80
513_T	517_E	0.802	0.80
12_I	26_V	0.801	0.80
511_I	530_M	0.799	0.80
72_L	101_L	0.799	0.80
408_M	412_D	0.797	0.80
315_K	352_A	0.797	0.80
201_E	394_R	0.796	0.80
33_I	66_R	0.795	0.79
227_V	295_A	0.794	0.79
19_E	22_K	0.790	0.79
302_Q	335_I	0.789	0.79
217_S	245_A	0.788	0.79
310_T	314_N	0.783	0.78
138_F	185_I	0.783	0.78
162_T	193_L	0.782	0.78
310_T	345_T	0.781	0.78
449_D	453_I	0.779	0.78
298_T	312_M	0.778	0.78
385_Y	429_V	0.778	0.78
27_I	133_T	0.778	0.78
103_L	263_V	0.777	0.78
219_A	327_T	0.774	0.78
189_G	384_K	0.773	0.78
9_V	27_I	0.771	0.77
195_S	408_M	0.771	0.77
122_I	128_I	0.769	0.77
302_Q	364_H	0.769	0.77
532_D	539_Y	0.769	0.77
79_N	142_H	0.768	0.77
376_L	379_N	0.765	0.77
417_E	420_D	0.764	0.77
470_V	553_M	0.760	0.76
345_T	349_L	0.759	0.76
302_Q	390_N	0.755	0.76
348_L	351_R	0.755	0.76
76_H	79_N	0.755	0.76
252_K	293_E	0.753	0.76
537_F	541_K	0.753	0.76
539_Y	543_K	0.753	0.76
125_K	181_E	0.749	0.75
220_L	249_N	0.749	0.75
403_A	408_M	0.745	0.75
507_L	510_S	0.744	0.75
197_S	392_E	0.744	0.75
157_G	191_L	0.743	0.75
420_D	434_K	0.741	0.75
68_K	132_S	0.738	0.74
286_V	320_L	0.738	0.74
193_L	386_L	0.737	0.74
159_I	192_A	0.736	0.74
214_G	218_D	0.735	0.74
343_S	347_D	0.734	0.74
105_R	121_E	0.733	0.74
164_D	390_N	0.731	0.74
242_V	297_I	0.731	0.74
100_T	148_V	0.731	0.74
106_E	109_K	0.730	0.73
158_S	185_I	0.728	0.73
78_E	142_H	0.728	0.73
550_P	553_M	0.727	0.73
453_I	456_R	0.725	0.73
327_T	357_I	0.724	0.73
387_I	416_I	0.724	0.73
246_A	253_I	0.722	0.73
204_G	370_S	0.722	0.73
205_Y	373_E	0.720	0.72
275_A	279_L	0.720	0.72
160_V	190_V	0.720	0.72
34_F	152_F	0.719	0.72
527_K	531_R	0.718	0.72
493_Y	501_I	0.718	0.72
24_L	38_A	0.717	0.72
69_A	95_Y	0.717	0.72
315_K	321_N	0.715	0.72
396_Q	399_H	0.714	0.72
502_V	507_L	0.713	0.72
506_E	510_S	0.713	0.72
191_L	385_Y	0.713	0.72
67_V	90_L	0.710	0.71
256_A	320_L	0.709	0.71
474_D	481_V	0.708	0.71
448_G	451_G	0.708	0.71
350_A	356_V	0.707	0.71
142_H	238_R	0.706	0.71
140_T	377_M	0.705	0.71
302_Q	337_G	0.705	0.71
255_V	297_I	0.703	0.71
78_E	366_S	0.702	0.70
256_A	312_M	0.701	0.70
139_R	175_Q	0.701	0.70
322_I	352_A	0.701	0.70
202_R	370_S	0.699	0.70
483_G	495_R	0.698	0.70
86_L	92_V	0.698	0.70
179_I	377_M	0.696	0.70
233_A	390_N	0.695	0.70
532_D	536_Q	0.693	0.70
76_H	366_S	0.692	0.69
71_F	131_E	0.690	0.69
315_K	329_V	0.690	0.69
33_I	63_R	0.689	0.69
259_N	302_Q	0.688	0.69
198_A	337_G	0.688	0.69
198_A	368_H	0.687	0.69
100_T	339_E	0.686	0.69
57_I	61_I	0.686	0.69
222_N	469_V	0.685	0.69
453_I	549_I	0.684	0.69
488_T	493_Y	0.684	0.69
241_Q	245_A	0.681	0.68
38_A	70_I	0.680	0.68
105_R	109_K	0.680	0.68
79_N	232_F	0.680	0.68
532_D	547_M	0.679	0.68
453_I	457_D	0.679	0.68
32_D	69_A	0.678	0.68
527_K	551_I	0.678	0.68
273_I	276_D	0.676	0.68
502_V	514_E	0.676	0.68
423_E	430_K	0.675	0.67
443_D	454_V	0.675	0.67
297_I	394_R	0.673	0.67
25_Y	194_L	0.672	0.67
209_E	303_G	0.671	0.67
228_I	312_M	0.670	0.67
442_I	448_G	0.669	0.67
488_T	491_F	0.669	0.67
24_L	57_I	0.668	0.67
355_Q	401_K	0.668	0.67
68_K	95_Y	0.668	0.67
531_R	550_P	0.665	0.66
59_Y	63_R	0.665	0.66
503_Q	506_E	0.665	0.66
209_E	364_H	0.665	0.66
97_T	122_I	0.664	0.66
159_I	194_L	0.664	0.66
286_V	296_I	0.664	0.66
493_Y	497_S	0.663	0.66
491_F	544_R	0.662	0.66
530_M	534_L	0.662	0.66
423_E	432_G	0.661	0.66
247_A	253_I	0.660	0.66
247_A	250_G	0.660	0.66
205_Y	370_S	0.660	0.66
474_D	484_P	0.659	0.66
513_T	519_S	0.659	0.66
312_M	317_H	0.659	0.66
513_T	516_T	0.659	0.66
147_S	369_G	0.659	0.66
15_G	21_G	0.658	0.66
539_Y	542_T	0.657	0.65
493_Y	539_Y	0.657	0.65
254_A	320_L	0.655	0.65
235_N	367_G	0.653	0.65
195_S	374_L	0.653	0.65
74_H	366_S	0.650	0.65
244_H	247_A	0.646	0.64
467_L	504_A	0.646	0.64
375_K	402_I	0.646	0.64
195_S	377_M	0.645	0.64
110_Q	113_H	0.645	0.64
544_R	550_P	0.644	0.64
54_I	447_V	0.643	0.64
446_G	450_I	0.643	0.64
495_R	532_D	0.643	0.64
338_Q	390_N	0.642	0.64
209_E	367_G	0.642	0.64
144_I	307_A	0.641	0.64
124_S	139_R	0.641	0.64
335_I	390_N	0.640	0.63
151_S	191_L	0.638	0.63
78_E	390_N	0.638	0.63
424_F	429_V	0.638	0.63
504_A	508_V	0.638	0.63
228_I	298_T	0.637	0.63
209_E	302_Q	0.636	0.63
162_T	198_A	0.636	0.63
185_I	381_L	0.635	0.63
505_T	509_R	0.635	0.63
508_V	533_A	0.634	0.63
522_E	525_T	0.632	0.62
514_E	525_T	0.631	0.62
314_N	348_L	0.630	0.62
445_L	449_D	0.629	0.62
281_I	285_D	0.629	0.62
489_R	549_I	0.628	0.62
137_F	148_V	0.628	0.62
122_I	135_V	0.626	0.62
109_K	112_G	0.626	0.62
523_W	527_K	0.624	0.61
94_V	104_L	0.623	0.61
399_H	408_M	0.623	0.61
216_I	245_A	0.622	0.61
501_I	505_T	0.620	0.61
471_I	481_V	0.620	0.61
399_H	403_A	0.619	0.61
224_Q	327_T	0.619	0.61
11_I	27_I	0.617	0.61
535_N	548_I	0.615	0.60
95_Y	120_R	0.615	0.60
347_D	353_G	0.614	0.60
243_I	247_A	0.613	0.60
322_I	349_L	0.613	0.60
219_A	363_V	0.612	0.60
534_L	538_L	0.611	0.60
507_L	513_T	0.611	0.60
8_N	26_V	0.611	0.60
55_P	82_G	0.611	0.60
50_I	529_A	0.611	0.60
536_Q	539_Y	0.611	0.60
42_H	259_N	0.610	0.60
183_A	186_G	0.610	0.60
536_Q	540_E	0.608	0.59
195_S	381_L	0.607	0.59
414_F	429_V	0.607	0.59
156_L	427_Q	0.607	0.59
321_N	536_Q	0.607	0.59
38_A	86_L	0.606	0.59
199_N	390_N	0.604	0.59
481_V	484_P	0.604	0.59
417_E	434_K	0.603	0.59
12_I	33_I	0.603	0.59
442_I	447_V	0.602	0.59
38_A	82_G	0.600	0.58
488_T	492_V	0.600	0.58
433_D	436_P	0.599	0.58
412_D	499_G	0.598	0.58
231_V	297_I	0.598	0.58
495_R	498_E	0.597	0.58
468_I	551_I	0.596	0.58
123_H	128_I	0.592	0.57
381_L	386_L	0.591	0.57
527_K	549_I	0.591	0.57
372_E	376_L	0.590	0.57
498_E	503_Q	0.590	0.57
14_L	435_V	0.589	0.57
538_L	542_T	0.589	0.57
371_Q	398_A	0.588	0.57
196_D	368_H	0.588	0.57
446_G	455_L	0.588	0.57
515_A	529_A	0.587	0.57
486_I	505_T	0.585	0.57
261_Q	282_S	0.584	0.56
443_D	456_R	0.584	0.56
517_E	520_N	0.583	0.56
483_G	509_R	0.583	0.56
112_G	180_G	0.582	0.56
181_E	530_M	0.582	0.56
42_H	302_Q	0.581	0.56
205_Y	376_L	0.581	0.56
200_A	413_I	0.580	0.56
375_K	406_T	0.580	0.56
512_V	520_N	0.578	0.56
523_W	549_I	0.578	0.56
384_K	426_G	0.577	0.56
351_R	393_Y	0.577	0.56
151_S	160_V	0.577	0.56
28_E	31_S	0.577	0.56
474_D	482_S	0.577	0.56
235_N	241_Q	0.577	0.56
486_I	501_I	0.575	0.55
336_P	364_H	0.575	0.55
461_L	464_D	0.574	0.55
10_R	66_R	0.574	0.55
80_I	104_L	0.574	0.55
527_K	542_T	0.574	0.55
215_E	218_D	0.574	0.55
78_E	163_G	0.574	0.55
35_V	70_I	0.574	0.55
504_A	539_Y	0.573	0.55
470_V	485_E	0.573	0.55
268_R	275_A	0.572	0.55
16_G	21_G	0.572	0.55
510_S	524_S	0.572	0.55
484_P	550_P	0.572	0.55
101_L	105_R	0.571	0.55
227_V	327_T	0.571	0.55
198_A	303_G	0.571	0.55
171_P	209_E	0.571	0.55
83_V	174_N	0.570	0.55
87_L	91_S	0.569	0.54
109_K	315_K	0.567	0.54
11_I	429_V	0.567	0.54
40_L	53_V	0.566	0.54
186_G	190_V	0.565	0.54
19_E	226_R	0.565	0.54
303_G	390_N	0.565	0.54
247_A	274_E	0.565	0.54
67_V	70_I	0.565	0.54
538_L	541_K	0.565	0.54
432_G	436_P	0.564	0.54
384_K	428_N	0.563	0.54
524_S	527_K	0.562	0.54
493_Y	542_T	0.562	0.54
387_I	424_F	0.561	0.53
198_A	302_Q	0.561	0.53
259_N	364_H	0.561	0.53
164_D	232_F	0.559	0.53
215_E	361_K	0.559	0.53
512_V	518_T	0.559	0.53
37_D	142_H	0.559	0.53
87_L	92_V	0.558	0.53
453_I	553_M	0.558	0.53
189_G	251_R	0.557	0.53
343_S	346_V	0.556	0.53
99_L	270_L	0.556	0.53
454_V	457_D	0.556	0.53
9_V	191_L	0.556	0.53
482_S	509_R	0.555	0.53
42_H	78_E	0.555	0.53
233_A	303_G	0.554	0.53
464_D	538_L	0.554	0.53
77_D	390_N	0.554	0.53
93_P	120_R	0.553	0.52
225_N	325_G	0.552	0.52
169_Q	376_L	0.552	0.52
186_G	380_L	0.552	0.52
482_S	553_M	0.551	0.52
304_E	390_N	0.549	0.52
259_N	338_Q	0.549	0.52
198_A	304_E	0.548	0.52
231_V	260_L	0.548	0.52
470_V	550_P	0.548	0.52
201_E	398_A	0.548	0.52
485_E	498_E	0.548	0.52
18_G	417_E	0.547	0.52
481_V	510_S	0.547	0.52
21_G	390_N	0.546	0.52
513_T	520_N	0.546	0.52
474_D	511_I	0.546	0.52
346_V	349_L	0.545	0.51
161_C	389_V	0.544	0.51
76_H	196_D	0.544	0.51
385_Y	427_Q	0.544	0.51
20_I	42_H	0.544	0.51
424_F	428_N	0.544	0.51
526_L	530_M	0.543	0.51
443_D	458_R	0.543	0.51
376_L	380_L	0.542	0.51
98_K	123_H	0.542	0.51
312_M	328_V	0.541	0.51
72_L	82_G	0.541	0.51
87_L	90_L	0.540	0.51
487_I	491_F	0.540	0.51
42_H	77_D	0.539	0.51
99_L	146_D	0.538	0.50
218_D	221_Y	0.538	0.50
142_H	164_D	0.538	0.50
536_Q	553_M	0.536	0.50
108_L	113_H	0.536	0.50
525_T	540_E	0.535	0.50
254_A	281_I	0.535	0.50
191_L	427_Q	0.534	0.50
100_T	122_I	0.533	0.50
454_V	468_I	0.533	0.50
511_I	514_E	0.531	0.50
169_Q	205_Y	0.531	0.50
492_V	495_R	0.531	0.50
140_T	160_V	0.531	0.50
497_S	501_I	0.530	0.49
336_P	367_G	0.530	0.49
180_G	187_N	0.530	0.49
452_N	468_I	0.530	0.49
226_R	291_K	0.530	0.49
527_K	552_I	0.529	0.49
505_T	533_A	0.529	0.49
128_I	137_F	0.529	0.49
232_F	303_G	0.528	0.49
211_A	362_R	0.528	0.49
532_D	542_T	0.528	0.49
485_E	505_T	0.527	0.49
534_L	544_R	0.526	0.49
74_H	164_D	0.526	0.49
102_A	266_L	0.526	0.49
448_G	455_L	0.526	0.49
166_K	209_E	0.525	0.49
501_I	530_M	0.525	0.49
475_K	478_K	0.525	0.49
476_Q	516_T	0.525	0.49
232_F	302_Q	0.524	0.49
296_I	308_A	0.524	0.49
441_L	455_L	0.524	0.49
84_F	240_Q	0.524	0.49
224_Q	227_V	0.523	0.49
522_E	531_R	0.523	0.49
245_A	540_E	0.523	0.49
539_Y	552_I	0.523	0.49
347_D	351_R	0.523	0.49
539_Y	545_K	0.522	0.48
91_S	117_T	0.521	0.48
510_S	514_E	0.520	0.48
61_I	90_L	0.520	0.48
480_L	509_R	0.519	0.48
27_I	34_F	0.519	0.48
453_I	470_V	0.519	0.48
332_S	337_G	0.519	0.48
529_A	545_K	0.517	0.48
8_N	512_V	0.516	0.48
168_D	209_E	0.516	0.48
222_N	355_Q	0.516	0.48
527_K	547_M	0.515	0.47
429_V	433_D	0.515	0.47
27_I	156_L	0.514	0.47
316_A	525_T	0.513	0.47
145_P	263_V	0.513	0.47
182_I	185_I	0.513	0.47
135_V	153_K	0.513	0.47
385_Y	428_N	0.512	0.47
215_E	219_A	0.512	0.47
209_E	233_A	0.512	0.47
470_V	479_H	0.512	0.47
228_I	322_I	0.512	0.47
141_I	177_C	0.511	0.47
54_I	446_G	0.511	0.47
78_E	232_F	0.510	0.47
274_E	277_D	0.509	0.47
449_D	454_V	0.508	0.47
369_G	373_E	0.508	0.47
232_F	364_H	0.507	0.46
518_T	536_Q	0.507	0.46
328_V	512_V	0.507	0.46
512_V	516_T	0.507	0.46
471_I	480_L	0.507	0.46
21_G	232_F	0.507	0.46
488_T	501_I	0.507	0.46
520_N	525_T	0.506	0.46
163_G	368_H	0.506	0.46
229_I	295_A	0.506	0.46
27_I	194_L	0.506	0.46
535_N	544_R	0.504	0.46
76_H	198_A	0.504	0.46
528_Q	535_N	0.504	0.46
344_K	348_L	0.503	0.46
330_I	345_T	0.503	0.46
542_T	545_K	0.503	0.46
160_V	182_I	0.503	0.46
451_G	491_F	0.502	0.46
524_S	528_Q	0.502	0.46
329_V	549_I	0.501	0.46
166_K	367_G	0.500	0.46
60_L	64_A	0.500	0.46
79_N	338_Q	0.500	0.46
151_S	188_S	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zq4A	3	0.9892	100	0.217	Contact Map
3bk2A	2	0.9748	100	0.24	Contact Map
2az4A	1	0.6937	100	0.507	Contact Map
3iekA	3	0.6937	100	0.541	Contact Map
2ycbA	2	0.7279	100	0.552	Contact Map
2i7tA	1	0.6721	100	0.552	Contact Map
2xr1A	2	0.7243	100	0.557	Contact Map
3af5A	1	0.7297	100	0.56	Contact Map
2i7xA	1	0.6991	100	0.596	Contact Map
4b87A	1	0.5802	100	0.638	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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