GREMLIN Database
SYP - Proline--tRNA ligase
UniProt: O31755 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 564 (558)
Sequences: 2235 (1291)
Seq/√Len: 54.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
254_K362_E6.8761.00
186_A192_V4.1841.00
256_H365_H3.5981.00
453_A462_L3.4611.00
57_V445_V3.2491.00
164_H169_S3.2191.00
452_I468_V2.9841.00
164_H173_T2.9671.00
256_H364_D2.9231.00
227_S396_G2.9101.00
171_D413_K2.8911.00
82_E119_R2.8681.00
288_R343_E2.8351.00
97_K103_E2.7991.00
227_S393_S2.7881.00
483_D487_E2.7511.00
179_E183_N2.7511.00
77_A81_Q2.7311.00
62_E133_Y2.7221.00
491_K495_D2.7191.00
51_Q54_Q2.6751.00
59_E187_R2.6281.00
224_S227_S2.5981.00
224_S396_G2.5511.00
393_S396_G2.4881.00
6_T67_V2.4211.00
63_K183_N2.4051.00
538_I551_E2.4001.00
416_T420_E2.3781.00
2_R490_E2.3771.00
253_E368_K2.3591.00
387_I400_I2.3431.00
460_K517_A2.3431.00
264_E268_A2.3251.00
14_V24_Q2.2981.00
52_N502_E2.2611.00
280_S291_L2.2501.00
224_S393_S2.2041.00
254_K365_H2.1821.00
171_D175_Q2.1701.00
332_F364_D2.1551.00
355_N369_N2.1541.00
318_T321_E2.1501.00
389_E401_R2.1381.00
550_T560_F2.1381.00
69_M114_I2.1371.00
472_D502_E2.1291.00
292_V384_L2.1261.00
88_T417_R2.1091.00
175_Q179_E2.1001.00
487_E491_K2.0671.00
473_L501_Y2.0631.00
526_I541_V2.0531.00
298_H349_A2.0481.00
66_A131_T2.0341.00
284_K289_F2.0231.00
282_L291_L2.0141.00
358_A370_V2.0101.00
260_V266_L1.9811.00
475_I505_Y1.9691.00
512_A516_F1.9581.00
169_S173_T1.9561.00
26_L149_L1.9531.00
6_T471_Y1.9411.00
26_L31_F1.9391.00
69_M117_L1.9341.00
53_I449_L1.9281.00
543_I546_T1.9181.00
225_D401_R1.9101.00
122_V130_L1.9021.00
475_I492_L1.8901.00
293_L346_A1.8870.99
169_S172_E1.8800.99
165_A426_Y1.8660.99
329_E363_G1.8650.99
172_E176_K1.8610.99
160_A177_M1.8500.99
48_K502_E1.8480.99
484_G535_D1.8390.99
488_L534_A1.8200.99
291_L338_I1.8120.99
367_Y370_V1.8020.99
272_V357_V1.7930.99
490_E494_A1.7670.99
278_I356_A1.7670.99
285_A314_V1.7340.99
538_I553_S1.7260.99
424_A436_M1.7100.99
345_Y384_L1.7050.99
86_W105_A1.6990.99
345_Y382_A1.6920.99
350_V353_M1.6910.99
64_I180_A1.6830.99
315_E321_E1.6690.99
466_K472_D1.6630.99
170_L413_K1.6610.99
425_T433_A1.6590.99
131_T160_A1.6580.99
107_G110_H1.6550.99
416_T437_L1.6500.99
222_A400_I1.6480.99
166_S169_S1.6400.99
92_E95_R1.6350.99
493_Y497_K1.6340.99
328_T333_V1.6290.98
553_S556_E1.6190.98
178_Y208_H1.6160.98
250_K253_E1.6140.98
355_N371_N1.6130.98
283_F300_V1.6120.98
64_I131_T1.6090.98
227_S395_D1.6060.98
292_V305_V1.6030.98
300_V305_V1.5970.98
362_E365_H1.5950.98
270_L368_K1.5880.98
488_L491_K1.5750.98
254_K367_Y1.5740.98
167_A437_L1.5720.98
477_A505_Y1.5600.98
284_K321_E1.5580.98
353_M356_A1.5500.98
332_F363_G1.5340.98
556_E559_A1.5120.98
270_L357_V1.5060.97
182_S192_V1.5000.97
253_E369_N1.4930.97
260_V269_F1.4910.97
474_H519_S1.4900.97
49_V449_L1.4860.97
174_Y208_H1.4850.97
393_S397_K1.4760.97
19_E23_H1.4680.97
220_T402_F1.4540.97
50_I446_S1.4530.97
173_T176_K1.4490.97
73_A106_L1.4490.97
504_L524_L1.4450.97
322_V330_P1.4450.97
55_Q59_E1.4360.97
284_K315_E1.4340.97
152_G446_S1.4280.96
428_D434_Q1.4230.96
97_K101_G1.4130.96
426_Y434_Q1.4110.96
114_I132_L1.4010.96
74_L96_L1.3970.96
259_N364_D1.3900.96
250_K369_N1.3850.96
426_Y436_M1.3790.96
263_I277_C1.3750.96
12_R514_V1.3730.96
247_E276_A1.3680.96
178_Y411_V1.3660.95
71_M114_I1.3630.95
64_I176_K1.3610.95
64_I177_M1.3600.95
263_I274_A1.3550.95
238_V387_I1.3540.95
74_L94_M1.3530.95
294_V300_V1.3480.95
60_E187_R1.3430.95
252_L367_Y1.3400.95
283_F302_D1.3400.95
425_T435_P1.3290.95
556_E560_F1.3290.95
466_K526_I1.3280.95
257_T366_H1.3150.94
541_V560_F1.3090.94
255_V270_L1.2950.94
267_T274_A1.2930.94
207_T410_Q1.2890.94
346_A378_I1.2840.94
265_E268_A1.2830.94
282_L333_V1.2780.94
176_K180_A1.2760.93
118_V122_V1.2670.93
304_K383_D1.2630.93
185_F443_I1.2610.93
42_Y46_A1.2560.93
57_V446_S1.2560.93
351_K381_F1.2520.93
527_R549_S1.2480.93
55_Q62_E1.2440.93
510_E514_V1.2430.93
227_S397_K1.2380.92
235_M307_N1.2350.92
219_D232_N1.2310.92
356_A372_V1.2300.92
293_L350_V1.2280.92
281_V300_V1.2260.92
520_D542_K1.2170.92
456_H545_Q1.2170.92
21_K457_H1.2160.92
293_L344_V1.2100.92
118_V132_L1.2080.91
17_D27_L1.2050.91
202_M440_C1.2040.91
331_G366_H1.2020.91
33_R121_E1.2010.91
63_K497_K1.1990.91
473_L496_L1.1980.91
165_A429_E1.1960.91
81_Q103_E1.1900.91
346_A381_F1.1860.91
289_F325_Q1.1840.91
26_L453_A1.1810.91
223_Y403_A1.1810.91
419_S424_A1.1800.90
229_Y400_I1.1780.90
51_Q62_E1.1700.90
417_R421_A1.1690.90
256_H362_E1.1670.90
278_I293_L1.1620.90
430_N434_Q1.1600.90
50_I156_I1.1600.90
526_I543_I1.1590.90
58_R68_E1.1590.90
223_Y401_R1.1530.89
156_I446_S1.1460.89
280_S293_L1.1460.89
493_Y505_Y1.1430.89
308_L384_L1.1370.89
267_T277_C1.1360.89
224_S397_K1.1330.89
116_S119_R1.1290.88
226_E397_K1.1280.88
263_I267_T1.1210.88
83_S89_Y1.1170.88
178_Y194_P1.1170.88
82_E422_M1.1160.88
81_Q87_Y1.1160.88
477_A486_R1.1140.88
328_T363_G1.1140.88
261_K265_E1.1140.88
476_L529_T1.1110.88
472_D501_Y1.1100.88
199_S207_T1.1040.87
528_I557_L1.1040.87
336_V367_Y1.0980.87
59_E63_K1.0920.87
541_V557_L1.0890.87
70_L73_A1.0860.86
533_R551_E1.0850.86
49_V464_W1.0810.86
485_Q534_A1.0800.86
115_T424_A1.0790.86
305_V384_L1.0770.86
416_T435_P1.0770.86
36_T104_F1.0770.86
488_L554_V1.0740.86
14_V27_L1.0700.86
263_I266_L1.0690.86
52_N55_Q1.0680.85
78_E81_Q1.0660.85
197_A410_Q1.0650.85
255_V266_L1.0610.85
237_E348_Q1.0610.85
164_H170_L1.0610.85
56_I188_C1.0590.85
47_Y51_Q1.0590.85
43_M117_L1.0570.85
528_I541_V1.0560.85
473_L528_I1.0530.85
373_N377_Q1.0500.84
21_K24_Q1.0480.84
257_T331_G1.0430.84
77_A103_E1.0380.84
199_S235_M1.0350.84
526_I561_I1.0340.84
266_L270_L1.0330.83
477_A489_A1.0300.83
541_V552_I1.0290.83
182_S186_A1.0240.83
228_Q399_T1.0230.83
42_Y50_I1.0220.83
168_E171_D1.0190.83
427_L432_R1.0140.82
222_A402_F1.0130.82
456_H463_I1.0130.82
149_L152_G1.0110.82
225_D399_T1.0090.82
494_A498_A1.0080.82
199_S208_H1.0040.82
420_E435_P1.0030.82
495_D498_A1.0030.82
36_T39_V1.0020.82
260_V332_F0.9990.81
224_S395_D0.9950.81
74_L106_L0.9930.81
343_E380_E0.9930.81
116_S120_D0.9900.81
178_Y182_S0.9890.81
285_A309_L0.9870.81
557_L561_I0.9870.81
31_F149_L0.9830.80
360_A365_H0.9800.80
246_D354_V0.9720.80
225_D228_Q0.9700.79
212_A410_Q0.9680.79
9_P43_M0.9670.79
206_D413_K0.9640.79
319_H323_I0.9620.79
252_L370_V0.9600.79
249_P354_V0.9600.79
323_I329_E0.9590.79
222_A387_I0.9580.79
35_N41_S0.9570.78
283_F316_L0.9560.78
3_Q504_L0.9540.78
89_Y93_L0.9530.78
322_V328_T0.9530.78
389_E402_F0.9510.78
419_S435_P0.9490.78
485_Q488_L0.9460.78
484_G488_L0.9420.77
475_I489_A0.9410.77
295_R298_H0.9410.77
370_V376_A0.9400.77
458_D544_R0.9400.77
490_E505_Y0.9350.77
252_L374_R0.9340.77
289_F317_A0.9340.77
175_Q178_Y0.9330.77
170_L206_D0.9330.77
79_T116_S0.9300.76
196_I235_M0.9280.76
89_Y201_A0.9270.76
337_G341_D0.9250.76
20_A216_I0.9220.76
183_N186_A0.9200.76
484_G487_E0.9160.75
170_L437_L0.9140.75
53_I448_T0.9140.75
279_K331_G0.9140.75
497_K502_E0.9130.75
212_A408_V0.9110.75
476_L527_R0.9110.75
326_L333_V0.9090.75
350_V381_F0.9080.75
315_E318_T0.9060.75
179_E182_S0.9020.74
1_M493_Y0.9000.74
3_Q474_H0.9000.74
70_L136_Q0.8980.74
247_E355_N0.8970.74
376_A379_K0.8970.74
255_V269_F0.8910.73
308_L382_A0.8900.73
252_L336_V0.8890.73
298_H385_R0.8890.73
110_H136_Q0.8890.73
266_L269_F0.8850.73
283_F292_V0.8850.73
553_S557_L0.8820.73
296_G366_H0.8810.72
166_S429_E0.8810.72
372_V381_F0.8800.72
258_P331_G0.8780.72
482_N532_K0.8760.72
279_K366_H0.8760.72
280_S333_V0.8750.72
266_L357_V0.8730.72
373_N376_A0.8720.72
264_E274_A0.8720.72
473_L557_L0.8710.72
179_E411_V0.8710.72
475_I503_V0.8710.72
476_L515_K0.8710.72
250_K368_K0.8700.72
52_N472_D0.8690.71
3_Q519_S0.8680.71
300_V384_L0.8660.71
542_K549_S0.8650.71
182_S194_P0.8650.71
3_Q8_I0.8650.71
463_I545_Q0.8640.71
249_P355_N0.8640.71
420_E425_T0.8560.70
77_A86_W0.8520.70
257_T279_K0.8500.70
419_S436_M0.8500.70
284_K287_D0.8470.69
110_H134_Q0.8460.69
453_A456_H0.8450.69
56_I467_S0.8450.69
483_D486_R0.8450.69
31_F462_L0.8440.69
491_K554_V0.8430.69
46_A53_I0.8400.69
329_E332_F0.8390.69
250_K355_N0.8380.69
475_I493_Y0.8370.69
150_L216_I0.8310.68
196_I208_H0.8310.68
237_E394_P0.8290.68
406_I451_A0.8290.68
73_A136_Q0.8290.68
308_L345_Y0.8280.68
131_T177_M0.8270.68
336_V370_V0.8270.68
303_I307_N0.8270.68
32_I149_L0.8260.68
420_E423_N0.8260.68
260_V265_E0.8250.67
258_P332_F0.8220.67
308_L380_E0.8200.67
292_V345_Y0.8190.67
254_K360_A0.8180.67
497_K503_V0.8180.67
158_K181_Y0.8130.66
89_Y202_M0.8110.66
475_I530_V0.8110.66
220_T404_E0.8100.66
296_G331_G0.8100.66
499_E558_S0.8080.66
486_R490_E0.8050.66
428_D433_A0.8050.66
458_D461_G0.8030.65
48_K52_N0.8030.65
6_T45_L0.8030.65
478_L531_G0.8020.65
474_H524_L0.8020.65
494_A497_K0.8020.65
177_M202_M0.8020.65
346_A350_V0.8020.65
91_P143_K0.7940.64
534_A554_V0.7930.64
250_K371_N0.7900.64
61_M158_K0.7890.64
286_D311_A0.7880.64
243_V352_A0.7880.64
215_A403_A0.7870.64
64_I179_E0.7860.64
79_T93_L0.7860.64
269_F368_K0.7840.63
295_R349_A0.7840.63
233_I402_F0.7810.63
492_L557_L0.7810.63
350_V356_A0.7810.63
285_A288_R0.7800.63
167_A416_T0.7780.63
520_D527_R0.7770.63
164_H172_E0.7770.63
283_F305_V0.7760.63
258_P366_H0.7760.63
546_T550_T0.7750.63
196_I395_D0.7730.62
273_S276_A0.7710.62
261_K280_S0.7690.62
214_S406_I0.7630.61
212_A455_Q0.7620.61
49_V524_L0.7620.61
8_I522_I0.7620.61
189_G456_H0.7610.61
21_K216_I0.7610.61
188_C468_V0.7600.61
378_I381_F0.7590.61
128_L426_Y0.7580.61
311_A314_V0.7580.61
5_L176_K0.7560.61
35_N113_V0.7530.60
63_K179_E0.7520.60
285_A311_A0.7510.60
457_H463_I0.7490.60
33_R43_M0.7480.60
289_F321_E0.7480.60
257_T296_G0.7470.60
82_E116_S0.7460.60
238_V391_D0.7460.60
86_W103_E0.7410.59
536_E551_E0.7390.59
212_A452_I0.7390.59
197_A207_T0.7380.59
326_L338_I0.7380.59
9_P33_R0.7370.59
128_L436_M0.7370.59
57_V443_I0.7350.58
267_T270_L0.7310.58
194_P410_Q0.7290.58
261_K332_F0.7270.58
35_N76_Q0.7250.57
94_M106_L0.7240.57
219_D410_Q0.7230.57
346_A351_K0.7220.57
114_I208_H0.7220.57
51_Q55_Q0.7210.57
41_S71_M0.7190.57
114_I440_C0.7190.57
531_G536_E0.7170.57
42_Y449_L0.7170.57
5_L65_D0.7120.56
395_D398_G0.7120.56
277_C333_V0.7110.56
31_F453_A0.7100.56
474_H504_L0.7090.56
393_S398_G0.7080.56
351_K372_V0.7080.56
479_N512_A0.7060.55
191_N455_Q0.7040.55
164_H440_C0.7030.55
272_V277_C0.7030.55
47_Y54_Q0.7020.55
256_H259_N0.7010.55
529_T549_S0.7000.55
81_Q86_W0.6980.55
56_I468_V0.6970.54
456_H462_L0.6970.54
33_R117_L0.6960.54
471_Y502_E0.6950.54
188_C448_T0.6940.54
12_R517_A0.6930.54
460_K547_G0.6920.54
96_L106_L0.6920.54
552_I557_L0.6910.54
192_V408_V0.6900.54
279_K296_G0.6890.54
489_A505_Y0.6870.53
259_N332_F0.6870.53
373_N378_I0.6860.53
277_C322_V0.6850.53
73_A137_S0.6850.53
485_Q532_K0.6850.53
108_A207_T0.6850.53
216_I220_T0.6840.53
348_Q351_K0.6830.53
410_Q448_T0.6810.53
299_E388_K0.6810.53
282_L317_A0.6810.53
533_R538_I0.6800.53
231_A236_A0.6790.53
45_L522_I0.6780.52
323_I328_T0.6780.52
225_D398_G0.6770.52
83_S191_N0.6760.52
71_M113_V0.6750.52
165_A169_S0.6720.52
126_K432_R0.6710.52
74_L105_A0.6710.52
256_H332_F0.6690.51
211_M233_I0.6690.51
39_V152_G0.6680.51
171_D206_D0.6680.51
298_H388_K0.6670.51
184_I443_I0.6670.51
338_I342_V0.6660.51
93_L202_M0.6660.51
336_V376_A0.6650.51
118_V130_L0.6650.51
281_V330_P0.6640.51
88_T201_A0.6630.51
423_N435_P0.6610.51
149_L446_S0.6600.51
543_I550_T0.6590.50
478_L512_A0.6560.50
477_A485_Q0.6560.50
535_D538_I0.6560.50
412_F442_G0.6550.50
539_V554_V0.6530.50
278_I358_A0.6520.50
372_V376_A0.6510.50
114_I202_M0.6510.50
118_V509_A0.6500.49
466_K541_V0.6500.49
334_G361_N0.6500.49
392_P399_T0.6490.49
75_Q114_I0.6480.49
149_L450_S0.6480.49
67_V130_L0.6470.49
53_I468_V0.6470.49
546_T549_S0.6470.49
255_V368_K0.6460.49
264_E299_E0.6440.49
263_I279_K0.6440.49
317_A322_V0.6430.49
527_R546_T0.6420.49
295_R385_R0.6420.49
64_I173_T0.6410.48
491_K498_A0.6400.48
222_A233_I0.6400.48
94_M105_A0.6400.48
75_Q113_V0.6390.48
552_I560_F0.6390.48
457_H462_L0.6390.48
53_I57_V0.6380.48
98_D102_R0.6370.48
407_E412_F0.6370.48
350_V372_V0.6360.48
357_V368_K0.6360.48
348_Q381_F0.6350.48
238_V383_D0.6350.48
274_A277_C0.6340.48
74_L139_F0.6330.48
152_G156_I0.6330.48
292_V300_V0.6320.48
52_N56_I0.6310.47
309_L343_E0.6290.47
15_P23_H0.6290.47
319_H330_P0.6290.47
20_A34_Q0.6290.47
328_T332_F0.6280.47
199_S206_D0.6270.47
492_L530_V0.6270.47
530_V534_A0.6260.47
291_L342_V0.6230.47
37_S147_F0.6230.47
59_E183_N0.6200.46
89_Y95_R0.6190.46
262_T265_E0.6190.46
452_I456_H0.6190.46
325_Q328_T0.6190.46
233_I386_F0.6180.46
424_A435_P0.6170.46
73_A105_A0.6170.46
164_H176_K0.6160.46
119_R422_M0.6150.46
326_L330_P0.6150.46
479_N482_N0.6150.46
432_R520_D0.6140.46
23_H34_Q0.6140.46
108_A197_A0.6140.46
47_Y485_Q0.6130.46
299_E386_F0.6130.46
237_E395_D0.6100.45
143_K150_L0.6100.45
256_H260_V0.6090.45
79_T113_V0.6090.45
82_E423_N0.6080.45
280_S322_V0.6070.45
126_K509_A0.6060.45
201_A303_I0.6060.45
423_N433_A0.6050.45
240_H348_Q0.6040.45
228_Q398_G0.6040.45
54_Q58_R0.6030.44
62_E65_D0.6020.44
179_E186_A0.6020.44
7_L67_V0.6010.44
63_K180_A0.5990.44
294_V349_A0.5980.44
262_T296_G0.5980.44
151_R412_F0.5970.44
531_G538_I0.5950.44
64_I160_A0.5950.44
281_V291_L0.5950.44
461_G544_R0.5950.44
150_L214_S0.5940.43
278_I372_V0.5940.43
58_R62_E0.5930.43
19_E34_Q0.5930.43
350_V376_A0.5930.43
282_L328_T0.5910.43
472_D524_L0.5910.43
193_R213_L0.5910.43
291_L326_L0.5890.43
323_I363_G0.5880.43
278_I353_M0.5880.43
7_L152_G0.5870.43
34_Q143_K0.5850.43
99_R141_D0.5850.43
542_K547_G0.5840.42
343_E379_K0.5840.42
122_V128_L0.5830.42
290_V314_V0.5830.42
330_P333_V0.5820.42
27_L221_I0.5820.42
471_Y504_L0.5800.42
276_A355_N0.5790.42
46_A449_L0.5790.42
552_I561_I0.5780.42
495_D559_A0.5780.42
18_A23_H0.5770.42
160_A440_C0.5770.42
216_I452_I0.5750.42
171_D437_L0.5750.42
279_K359_G0.5750.42
326_L329_E0.5740.41
199_S211_M0.5720.41
432_R509_A0.5720.41
202_M419_S0.5720.41
433_A520_D0.5710.41
151_R407_E0.5710.41
466_K545_Q0.5690.41
416_T419_S0.5690.41
89_Y152_G0.5680.41
453_A457_H0.5680.41
387_I390_G0.5680.41
305_V382_A0.5670.41
7_L132_L0.5650.40
41_S72_P0.5650.40
228_Q397_K0.5640.40
543_I547_G0.5640.40
157_M412_F0.5630.40
372_V378_I0.5620.40
188_C211_M0.5600.40
319_H322_V0.5600.40
413_K437_L0.5600.40
71_M75_Q0.5590.40
49_V453_A0.5580.40
306_K311_A0.5560.40
157_M442_G0.5560.40
238_V348_Q0.5540.39
63_K498_A0.5540.39
372_V379_K0.5540.39
289_F520_D0.5530.39
427_L433_A0.5520.39
288_R341_D0.5520.39
497_K501_Y0.5500.39
35_N137_S0.5490.39
107_G212_A0.5480.39
532_K535_D0.5480.39
62_E66_A0.5480.39
48_K62_E0.5470.39
245_S354_V0.5460.39
472_D497_K0.5450.38
180_A184_I0.5450.38
83_S95_R0.5440.38
528_I539_V0.5440.38
244_P352_A0.5420.38
338_I341_D0.5420.38
334_G360_A0.5420.38
7_L122_V0.5420.38
321_E324_Q0.5420.38
59_E81_Q0.5410.38
106_L152_G0.5410.38
302_D400_I0.5410.38
280_S343_E0.5410.38
460_K520_D0.5410.38
232_N410_Q0.5410.38
258_P296_G0.5400.38
92_E100_H0.5400.38
246_D249_P0.5390.38
107_G134_Q0.5390.38
61_M66_A0.5380.38
31_F299_E0.5380.38
328_T358_A0.5380.38
185_F530_V0.5370.38
75_Q202_M0.5370.38
9_P45_L0.5370.38
89_Y143_K0.5360.38
277_C280_S0.5360.38
29_A458_D0.5350.37
40_Y406_I0.5350.37
166_S437_L0.5350.37
361_N366_H0.5340.37
282_L326_L0.5340.37
168_E172_E0.5340.37
322_V333_V0.5330.37
80_W84_G0.5330.37
11_L510_E0.5330.37
199_S205_K0.5320.37
190_I451_A0.5320.37
55_Q63_K0.5310.37
241_Q352_A0.5300.37
285_A290_V0.5300.37
495_D558_S0.5290.37
115_T440_C0.5280.37
19_E102_R0.5270.37
20_A450_S0.5270.37
263_I331_G0.5270.37
149_L453_A0.5260.37
200_G412_F0.5260.37
185_F448_T0.5260.37
359_G366_H0.5260.37
260_V358_A0.5250.36
67_V515_K0.5250.36
257_T263_I0.5250.36
252_L368_K0.5250.36
7_L282_L0.5240.36
106_L117_L0.5230.36
320_E323_I0.5230.36
78_E102_R0.5230.36
15_P18_A0.5220.36
13_E456_H0.5210.36
46_A156_I0.5210.36
263_I366_H0.5200.36
199_S307_N0.5200.36
533_R549_S0.5200.36
42_Y152_G0.5200.36
351_K378_I0.5200.36
277_C357_V0.5190.36
89_Y108_A0.5190.36
26_L51_Q0.5190.36
259_N537_G0.5180.36
543_I549_S0.5170.36
21_K456_H0.5170.36
334_G359_G0.5170.36
73_A219_D0.5160.36
66_A176_K0.5160.36
6_T31_F0.5160.36
25_L457_H0.5160.36
198_D307_N0.5150.35
167_A171_D0.5150.35
239_L397_K0.5130.35
77_A87_Y0.5130.35
168_E491_K0.5130.35
422_M436_M0.5120.35
83_S201_A0.5120.35
137_S219_D0.5120.35
259_N363_G0.5120.35
151_R200_G0.5100.35
64_I212_A0.5100.35
144_R407_E0.5100.35
418_Y442_G0.5100.35
34_Q105_A0.5100.35
222_A235_M0.5090.35
211_M437_L0.5090.35
258_P269_F0.5080.35
319_H329_E0.5080.35
35_N116_S0.5060.35
331_G359_G0.5060.35
428_D432_R0.5060.35
222_A389_E0.5060.35
490_E493_Y0.5060.35
182_S411_V0.5050.34
305_V345_Y0.5050.34
73_A139_F0.5050.34
281_V334_G0.5050.34
526_I529_T0.5050.34
221_I235_M0.5040.34
489_A528_I0.5040.34
407_E442_G0.5040.34
193_R228_Q0.5040.34
280_S330_P0.5040.34
147_F214_S0.5030.34
334_G366_H0.5030.34
331_G334_G0.5030.34
84_G180_A0.5030.34
280_S358_A0.5030.34
474_H505_Y0.5030.34
107_G136_Q0.5020.34
109_T412_F0.5020.34
93_L440_C0.5020.34
496_L501_Y0.5020.34
143_K147_F0.5010.34
66_A177_M0.5000.34
266_L366_H0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2j3lA 2 1 100 0.443 Contact Map
2i4lA 2 0.7748 100 0.534 Contact Map
4phcA 2 0.7784 100 0.65 Contact Map
4hvcA 2 0.6596 100 0.674 Contact Map
2zt5A 2 0.7181 100 0.678 Contact Map
1qf6A 1 0.7057 100 0.685 Contact Map
1nj8A 2 0.6454 100 0.691 Contact Map
3ialA 2 0.656 100 0.693 Contact Map
1nj1A 2 0.6418 100 0.699 Contact Map
4ncxA 2 0.6117 100 0.701 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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