SYP - BACSU - GREMLIN Contacts

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SYP - Proline--tRNA ligase

UniProt:	O31755	Sequences: MRQSLTLIPTLREVPADAEAKSHQLLLRAGFIRQNTSGVYSYMPLAYKVIQNIQQIVREEMEKIDAVEMLMPALQQAETWQESGRWYTYGPELMRLKDRHGREFALGATHEEVITSLVRDEVKSYKRLPLTLYQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHASAESLDETYQKMYEAYSNIFARCGINVRPVIADSGAMGGKDTHEFMALSAIGEDTIAYSDESQYAANIEMAEVLHQEVPSDEEPKALEKVHTPNVKTIEELTAFLQVSAEACIKSVLFKADDRFVLVLVRGDHEVNDIKVKNLLHAEVVELATHEEVIQQLGTEPGFVGPVGIHQDVEVYADQAVKAMVNAVAGANEGDHHYKNVNVNRDAQIKEFADLRFIKEGDPSPDGKGTIRFAEGIEVGQVFKLGTRYSEAMNATYLDENGRAQPMLMGCYGIGVSRTLSAIAEQHHDEKGLIWPKSVAPYDLHILALNMKNDGQRELAEKLYADLKAEGYEVLYDDRAERAGVKFADSDLIGLPIRITVGKRADEGIVEVKIRQTGESTEISVDELSAFISKQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	564 (558)
Sequences:	2235 (1291)
Seq/√Len:	54.7

ECOLI - SYP
BACSU - SYP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
254_K	362_E	6.876	1.00
186_A	192_V	4.184	1.00
256_H	365_H	3.598	1.00
453_A	462_L	3.461	1.00
57_V	445_V	3.249	1.00
164_H	169_S	3.219	1.00
452_I	468_V	2.984	1.00
164_H	173_T	2.967	1.00
256_H	364_D	2.923	1.00
227_S	396_G	2.910	1.00
171_D	413_K	2.891	1.00
82_E	119_R	2.868	1.00
288_R	343_E	2.835	1.00
97_K	103_E	2.799	1.00
227_S	393_S	2.788	1.00
483_D	487_E	2.751	1.00
179_E	183_N	2.751	1.00
77_A	81_Q	2.731	1.00
62_E	133_Y	2.722	1.00
491_K	495_D	2.719	1.00
51_Q	54_Q	2.675	1.00
59_E	187_R	2.628	1.00
224_S	227_S	2.598	1.00
224_S	396_G	2.551	1.00
393_S	396_G	2.488	1.00
6_T	67_V	2.421	1.00
63_K	183_N	2.405	1.00
538_I	551_E	2.400	1.00
416_T	420_E	2.378	1.00
2_R	490_E	2.377	1.00
253_E	368_K	2.359	1.00
387_I	400_I	2.343	1.00
460_K	517_A	2.343	1.00
264_E	268_A	2.325	1.00
14_V	24_Q	2.298	1.00
52_N	502_E	2.261	1.00
280_S	291_L	2.250	1.00
224_S	393_S	2.204	1.00
254_K	365_H	2.182	1.00
171_D	175_Q	2.170	1.00
332_F	364_D	2.155	1.00
355_N	369_N	2.154	1.00
318_T	321_E	2.150	1.00
389_E	401_R	2.138	1.00
550_T	560_F	2.138	1.00
69_M	114_I	2.137	1.00
472_D	502_E	2.129	1.00
292_V	384_L	2.126	1.00
88_T	417_R	2.109	1.00
175_Q	179_E	2.100	1.00
487_E	491_K	2.067	1.00
473_L	501_Y	2.063	1.00
526_I	541_V	2.053	1.00
298_H	349_A	2.048	1.00
66_A	131_T	2.034	1.00
284_K	289_F	2.023	1.00
282_L	291_L	2.014	1.00
358_A	370_V	2.010	1.00
260_V	266_L	1.981	1.00
475_I	505_Y	1.969	1.00
512_A	516_F	1.958	1.00
169_S	173_T	1.956	1.00
26_L	149_L	1.953	1.00
6_T	471_Y	1.941	1.00
26_L	31_F	1.939	1.00
69_M	117_L	1.934	1.00
53_I	449_L	1.928	1.00
543_I	546_T	1.918	1.00
225_D	401_R	1.910	1.00
122_V	130_L	1.902	1.00
475_I	492_L	1.890	1.00
293_L	346_A	1.887	0.99
169_S	172_E	1.880	0.99
165_A	426_Y	1.866	0.99
329_E	363_G	1.865	0.99
172_E	176_K	1.861	0.99
160_A	177_M	1.850	0.99
48_K	502_E	1.848	0.99
484_G	535_D	1.839	0.99
488_L	534_A	1.820	0.99
291_L	338_I	1.812	0.99
367_Y	370_V	1.802	0.99
272_V	357_V	1.793	0.99
490_E	494_A	1.767	0.99
278_I	356_A	1.767	0.99
285_A	314_V	1.734	0.99
538_I	553_S	1.726	0.99
424_A	436_M	1.710	0.99
345_Y	384_L	1.705	0.99
86_W	105_A	1.699	0.99
345_Y	382_A	1.692	0.99
350_V	353_M	1.691	0.99
64_I	180_A	1.683	0.99
315_E	321_E	1.669	0.99
466_K	472_D	1.663	0.99
170_L	413_K	1.661	0.99
425_T	433_A	1.659	0.99
131_T	160_A	1.658	0.99
107_G	110_H	1.655	0.99
416_T	437_L	1.650	0.99
222_A	400_I	1.648	0.99
166_S	169_S	1.640	0.99
92_E	95_R	1.635	0.99
493_Y	497_K	1.634	0.99
328_T	333_V	1.629	0.98
553_S	556_E	1.619	0.98
178_Y	208_H	1.616	0.98
250_K	253_E	1.614	0.98
355_N	371_N	1.613	0.98
283_F	300_V	1.612	0.98
64_I	131_T	1.609	0.98
227_S	395_D	1.606	0.98
292_V	305_V	1.603	0.98
300_V	305_V	1.597	0.98
362_E	365_H	1.595	0.98
270_L	368_K	1.588	0.98
488_L	491_K	1.575	0.98
254_K	367_Y	1.574	0.98
167_A	437_L	1.572	0.98
477_A	505_Y	1.560	0.98
284_K	321_E	1.558	0.98
353_M	356_A	1.550	0.98
332_F	363_G	1.534	0.98
556_E	559_A	1.512	0.98
270_L	357_V	1.506	0.97
182_S	192_V	1.500	0.97
253_E	369_N	1.493	0.97
260_V	269_F	1.491	0.97
474_H	519_S	1.490	0.97
49_V	449_L	1.486	0.97
174_Y	208_H	1.485	0.97
393_S	397_K	1.476	0.97
19_E	23_H	1.468	0.97
220_T	402_F	1.454	0.97
50_I	446_S	1.453	0.97
173_T	176_K	1.449	0.97
73_A	106_L	1.449	0.97
504_L	524_L	1.445	0.97
322_V	330_P	1.445	0.97
55_Q	59_E	1.436	0.97
284_K	315_E	1.434	0.97
152_G	446_S	1.428	0.96
428_D	434_Q	1.423	0.96
97_K	101_G	1.413	0.96
426_Y	434_Q	1.411	0.96
114_I	132_L	1.401	0.96
74_L	96_L	1.397	0.96
259_N	364_D	1.390	0.96
250_K	369_N	1.385	0.96
426_Y	436_M	1.379	0.96
263_I	277_C	1.375	0.96
12_R	514_V	1.373	0.96
247_E	276_A	1.368	0.96
178_Y	411_V	1.366	0.95
71_M	114_I	1.363	0.95
64_I	176_K	1.361	0.95
64_I	177_M	1.360	0.95
263_I	274_A	1.355	0.95
238_V	387_I	1.354	0.95
74_L	94_M	1.353	0.95
294_V	300_V	1.348	0.95
60_E	187_R	1.343	0.95
252_L	367_Y	1.340	0.95
283_F	302_D	1.340	0.95
425_T	435_P	1.329	0.95
556_E	560_F	1.329	0.95
466_K	526_I	1.328	0.95
257_T	366_H	1.315	0.94
541_V	560_F	1.309	0.94
255_V	270_L	1.295	0.94
267_T	274_A	1.293	0.94
207_T	410_Q	1.289	0.94
346_A	378_I	1.284	0.94
265_E	268_A	1.283	0.94
282_L	333_V	1.278	0.94
176_K	180_A	1.276	0.93
118_V	122_V	1.267	0.93
304_K	383_D	1.263	0.93
185_F	443_I	1.261	0.93
42_Y	46_A	1.256	0.93
57_V	446_S	1.256	0.93
351_K	381_F	1.252	0.93
527_R	549_S	1.248	0.93
55_Q	62_E	1.244	0.93
510_E	514_V	1.243	0.93
227_S	397_K	1.238	0.92
235_M	307_N	1.235	0.92
219_D	232_N	1.231	0.92
356_A	372_V	1.230	0.92
293_L	350_V	1.228	0.92
281_V	300_V	1.226	0.92
520_D	542_K	1.217	0.92
456_H	545_Q	1.217	0.92
21_K	457_H	1.216	0.92
293_L	344_V	1.210	0.92
118_V	132_L	1.208	0.91
17_D	27_L	1.205	0.91
202_M	440_C	1.204	0.91
331_G	366_H	1.202	0.91
33_R	121_E	1.201	0.91
63_K	497_K	1.199	0.91
473_L	496_L	1.198	0.91
165_A	429_E	1.196	0.91
81_Q	103_E	1.190	0.91
346_A	381_F	1.186	0.91
289_F	325_Q	1.184	0.91
26_L	453_A	1.181	0.91
223_Y	403_A	1.181	0.91
419_S	424_A	1.180	0.90
229_Y	400_I	1.178	0.90
51_Q	62_E	1.170	0.90
417_R	421_A	1.169	0.90
256_H	362_E	1.167	0.90
278_I	293_L	1.162	0.90
430_N	434_Q	1.160	0.90
50_I	156_I	1.160	0.90
526_I	543_I	1.159	0.90
58_R	68_E	1.159	0.90
223_Y	401_R	1.153	0.89
156_I	446_S	1.146	0.89
280_S	293_L	1.146	0.89
493_Y	505_Y	1.143	0.89
308_L	384_L	1.137	0.89
267_T	277_C	1.136	0.89
224_S	397_K	1.133	0.89
116_S	119_R	1.129	0.88
226_E	397_K	1.128	0.88
263_I	267_T	1.121	0.88
83_S	89_Y	1.117	0.88
178_Y	194_P	1.117	0.88
82_E	422_M	1.116	0.88
81_Q	87_Y	1.116	0.88
477_A	486_R	1.114	0.88
328_T	363_G	1.114	0.88
261_K	265_E	1.114	0.88
476_L	529_T	1.111	0.88
472_D	501_Y	1.110	0.88
199_S	207_T	1.104	0.87
528_I	557_L	1.104	0.87
336_V	367_Y	1.098	0.87
59_E	63_K	1.092	0.87
541_V	557_L	1.089	0.87
70_L	73_A	1.086	0.86
533_R	551_E	1.085	0.86
49_V	464_W	1.081	0.86
485_Q	534_A	1.080	0.86
115_T	424_A	1.079	0.86
305_V	384_L	1.077	0.86
416_T	435_P	1.077	0.86
36_T	104_F	1.077	0.86
488_L	554_V	1.074	0.86
14_V	27_L	1.070	0.86
263_I	266_L	1.069	0.86
52_N	55_Q	1.068	0.85
78_E	81_Q	1.066	0.85
197_A	410_Q	1.065	0.85
255_V	266_L	1.061	0.85
237_E	348_Q	1.061	0.85
164_H	170_L	1.061	0.85
56_I	188_C	1.059	0.85
47_Y	51_Q	1.059	0.85
43_M	117_L	1.057	0.85
528_I	541_V	1.056	0.85
473_L	528_I	1.053	0.85
373_N	377_Q	1.050	0.84
21_K	24_Q	1.048	0.84
257_T	331_G	1.043	0.84
77_A	103_E	1.038	0.84
199_S	235_M	1.035	0.84
526_I	561_I	1.034	0.84
266_L	270_L	1.033	0.83
477_A	489_A	1.030	0.83
541_V	552_I	1.029	0.83
182_S	186_A	1.024	0.83
228_Q	399_T	1.023	0.83
42_Y	50_I	1.022	0.83
168_E	171_D	1.019	0.83
427_L	432_R	1.014	0.82
222_A	402_F	1.013	0.82
456_H	463_I	1.013	0.82
149_L	152_G	1.011	0.82
225_D	399_T	1.009	0.82
494_A	498_A	1.008	0.82
199_S	208_H	1.004	0.82
420_E	435_P	1.003	0.82
495_D	498_A	1.003	0.82
36_T	39_V	1.002	0.82
260_V	332_F	0.999	0.81
224_S	395_D	0.995	0.81
74_L	106_L	0.993	0.81
343_E	380_E	0.993	0.81
116_S	120_D	0.990	0.81
178_Y	182_S	0.989	0.81
285_A	309_L	0.987	0.81
557_L	561_I	0.987	0.81
31_F	149_L	0.983	0.80
360_A	365_H	0.980	0.80
246_D	354_V	0.972	0.80
225_D	228_Q	0.970	0.79
212_A	410_Q	0.968	0.79
9_P	43_M	0.967	0.79
206_D	413_K	0.964	0.79
319_H	323_I	0.962	0.79
252_L	370_V	0.960	0.79
249_P	354_V	0.960	0.79
323_I	329_E	0.959	0.79
222_A	387_I	0.958	0.79
35_N	41_S	0.957	0.78
283_F	316_L	0.956	0.78
3_Q	504_L	0.954	0.78
89_Y	93_L	0.953	0.78
322_V	328_T	0.953	0.78
389_E	402_F	0.951	0.78
419_S	435_P	0.949	0.78
485_Q	488_L	0.946	0.78
484_G	488_L	0.942	0.77
475_I	489_A	0.941	0.77
295_R	298_H	0.941	0.77
370_V	376_A	0.940	0.77
458_D	544_R	0.940	0.77
490_E	505_Y	0.935	0.77
252_L	374_R	0.934	0.77
289_F	317_A	0.934	0.77
175_Q	178_Y	0.933	0.77
170_L	206_D	0.933	0.77
79_T	116_S	0.930	0.76
196_I	235_M	0.928	0.76
89_Y	201_A	0.927	0.76
337_G	341_D	0.925	0.76
20_A	216_I	0.922	0.76
183_N	186_A	0.920	0.76
484_G	487_E	0.916	0.75
170_L	437_L	0.914	0.75
53_I	448_T	0.914	0.75
279_K	331_G	0.914	0.75
497_K	502_E	0.913	0.75
212_A	408_V	0.911	0.75
476_L	527_R	0.911	0.75
326_L	333_V	0.909	0.75
350_V	381_F	0.908	0.75
315_E	318_T	0.906	0.75
179_E	182_S	0.902	0.74
1_M	493_Y	0.900	0.74
3_Q	474_H	0.900	0.74
70_L	136_Q	0.898	0.74
247_E	355_N	0.897	0.74
376_A	379_K	0.897	0.74
255_V	269_F	0.891	0.73
308_L	382_A	0.890	0.73
252_L	336_V	0.889	0.73
298_H	385_R	0.889	0.73
110_H	136_Q	0.889	0.73
266_L	269_F	0.885	0.73
283_F	292_V	0.885	0.73
553_S	557_L	0.882	0.73
296_G	366_H	0.881	0.72
166_S	429_E	0.881	0.72
372_V	381_F	0.880	0.72
258_P	331_G	0.878	0.72
482_N	532_K	0.876	0.72
279_K	366_H	0.876	0.72
280_S	333_V	0.875	0.72
266_L	357_V	0.873	0.72
373_N	376_A	0.872	0.72
264_E	274_A	0.872	0.72
473_L	557_L	0.871	0.72
179_E	411_V	0.871	0.72
475_I	503_V	0.871	0.72
476_L	515_K	0.871	0.72
250_K	368_K	0.870	0.72
52_N	472_D	0.869	0.71
3_Q	519_S	0.868	0.71
300_V	384_L	0.866	0.71
542_K	549_S	0.865	0.71
182_S	194_P	0.865	0.71
3_Q	8_I	0.865	0.71
463_I	545_Q	0.864	0.71
249_P	355_N	0.864	0.71
420_E	425_T	0.856	0.70
77_A	86_W	0.852	0.70
257_T	279_K	0.850	0.70
419_S	436_M	0.850	0.70
284_K	287_D	0.847	0.69
110_H	134_Q	0.846	0.69
453_A	456_H	0.845	0.69
56_I	467_S	0.845	0.69
483_D	486_R	0.845	0.69
31_F	462_L	0.844	0.69
491_K	554_V	0.843	0.69
46_A	53_I	0.840	0.69
329_E	332_F	0.839	0.69
250_K	355_N	0.838	0.69
475_I	493_Y	0.837	0.69
150_L	216_I	0.831	0.68
196_I	208_H	0.831	0.68
237_E	394_P	0.829	0.68
406_I	451_A	0.829	0.68
73_A	136_Q	0.829	0.68
308_L	345_Y	0.828	0.68
131_T	177_M	0.827	0.68
336_V	370_V	0.827	0.68
303_I	307_N	0.827	0.68
32_I	149_L	0.826	0.68
420_E	423_N	0.826	0.68
260_V	265_E	0.825	0.67
258_P	332_F	0.822	0.67
308_L	380_E	0.820	0.67
292_V	345_Y	0.819	0.67
254_K	360_A	0.818	0.67
497_K	503_V	0.818	0.67
158_K	181_Y	0.813	0.66
89_Y	202_M	0.811	0.66
475_I	530_V	0.811	0.66
220_T	404_E	0.810	0.66
296_G	331_G	0.810	0.66
499_E	558_S	0.808	0.66
486_R	490_E	0.805	0.66
428_D	433_A	0.805	0.66
458_D	461_G	0.803	0.65
48_K	52_N	0.803	0.65
6_T	45_L	0.803	0.65
478_L	531_G	0.802	0.65
474_H	524_L	0.802	0.65
494_A	497_K	0.802	0.65
177_M	202_M	0.802	0.65
346_A	350_V	0.802	0.65
91_P	143_K	0.794	0.64
534_A	554_V	0.793	0.64
250_K	371_N	0.790	0.64
61_M	158_K	0.789	0.64
286_D	311_A	0.788	0.64
243_V	352_A	0.788	0.64
215_A	403_A	0.787	0.64
64_I	179_E	0.786	0.64
79_T	93_L	0.786	0.64
269_F	368_K	0.784	0.63
295_R	349_A	0.784	0.63
233_I	402_F	0.781	0.63
492_L	557_L	0.781	0.63
350_V	356_A	0.781	0.63
285_A	288_R	0.780	0.63
167_A	416_T	0.778	0.63
520_D	527_R	0.777	0.63
164_H	172_E	0.777	0.63
283_F	305_V	0.776	0.63
258_P	366_H	0.776	0.63
546_T	550_T	0.775	0.63
196_I	395_D	0.773	0.62
273_S	276_A	0.771	0.62
261_K	280_S	0.769	0.62
214_S	406_I	0.763	0.61
212_A	455_Q	0.762	0.61
49_V	524_L	0.762	0.61
8_I	522_I	0.762	0.61
189_G	456_H	0.761	0.61
21_K	216_I	0.761	0.61
188_C	468_V	0.760	0.61
378_I	381_F	0.759	0.61
128_L	426_Y	0.758	0.61
311_A	314_V	0.758	0.61
5_L	176_K	0.756	0.61
35_N	113_V	0.753	0.60
63_K	179_E	0.752	0.60
285_A	311_A	0.751	0.60
457_H	463_I	0.749	0.60
33_R	43_M	0.748	0.60
289_F	321_E	0.748	0.60
257_T	296_G	0.747	0.60
82_E	116_S	0.746	0.60
238_V	391_D	0.746	0.60
86_W	103_E	0.741	0.59
536_E	551_E	0.739	0.59
212_A	452_I	0.739	0.59
197_A	207_T	0.738	0.59
326_L	338_I	0.738	0.59
9_P	33_R	0.737	0.59
128_L	436_M	0.737	0.59
57_V	443_I	0.735	0.58
267_T	270_L	0.731	0.58
194_P	410_Q	0.729	0.58
261_K	332_F	0.727	0.58
35_N	76_Q	0.725	0.57
94_M	106_L	0.724	0.57
219_D	410_Q	0.723	0.57
346_A	351_K	0.722	0.57
114_I	208_H	0.722	0.57
51_Q	55_Q	0.721	0.57
41_S	71_M	0.719	0.57
114_I	440_C	0.719	0.57
531_G	536_E	0.717	0.57
42_Y	449_L	0.717	0.57
5_L	65_D	0.712	0.56
395_D	398_G	0.712	0.56
277_C	333_V	0.711	0.56
31_F	453_A	0.710	0.56
474_H	504_L	0.709	0.56
393_S	398_G	0.708	0.56
351_K	372_V	0.708	0.56
479_N	512_A	0.706	0.55
191_N	455_Q	0.704	0.55
164_H	440_C	0.703	0.55
272_V	277_C	0.703	0.55
47_Y	54_Q	0.702	0.55
256_H	259_N	0.701	0.55
529_T	549_S	0.700	0.55
81_Q	86_W	0.698	0.55
56_I	468_V	0.697	0.54
456_H	462_L	0.697	0.54
33_R	117_L	0.696	0.54
471_Y	502_E	0.695	0.54
188_C	448_T	0.694	0.54
12_R	517_A	0.693	0.54
460_K	547_G	0.692	0.54
96_L	106_L	0.692	0.54
552_I	557_L	0.691	0.54
192_V	408_V	0.690	0.54
279_K	296_G	0.689	0.54
489_A	505_Y	0.687	0.53
259_N	332_F	0.687	0.53
373_N	378_I	0.686	0.53
277_C	322_V	0.685	0.53
73_A	137_S	0.685	0.53
485_Q	532_K	0.685	0.53
108_A	207_T	0.685	0.53
216_I	220_T	0.684	0.53
348_Q	351_K	0.683	0.53
410_Q	448_T	0.681	0.53
299_E	388_K	0.681	0.53
282_L	317_A	0.681	0.53
533_R	538_I	0.680	0.53
231_A	236_A	0.679	0.53
45_L	522_I	0.678	0.52
323_I	328_T	0.678	0.52
225_D	398_G	0.677	0.52
83_S	191_N	0.676	0.52
71_M	113_V	0.675	0.52
165_A	169_S	0.672	0.52
126_K	432_R	0.671	0.52
74_L	105_A	0.671	0.52
256_H	332_F	0.669	0.51
211_M	233_I	0.669	0.51
39_V	152_G	0.668	0.51
171_D	206_D	0.668	0.51
298_H	388_K	0.667	0.51
184_I	443_I	0.667	0.51
338_I	342_V	0.666	0.51
93_L	202_M	0.666	0.51
336_V	376_A	0.665	0.51
118_V	130_L	0.665	0.51
281_V	330_P	0.664	0.51
88_T	201_A	0.663	0.51
423_N	435_P	0.661	0.51
149_L	446_S	0.660	0.51
543_I	550_T	0.659	0.50
478_L	512_A	0.656	0.50
477_A	485_Q	0.656	0.50
535_D	538_I	0.656	0.50
412_F	442_G	0.655	0.50
539_V	554_V	0.653	0.50
278_I	358_A	0.652	0.50
372_V	376_A	0.651	0.50
114_I	202_M	0.651	0.50
118_V	509_A	0.650	0.49
466_K	541_V	0.650	0.49
334_G	361_N	0.650	0.49
392_P	399_T	0.649	0.49
75_Q	114_I	0.648	0.49
149_L	450_S	0.648	0.49
67_V	130_L	0.647	0.49
53_I	468_V	0.647	0.49
546_T	549_S	0.647	0.49
255_V	368_K	0.646	0.49
264_E	299_E	0.644	0.49
263_I	279_K	0.644	0.49
317_A	322_V	0.643	0.49
527_R	546_T	0.642	0.49
295_R	385_R	0.642	0.49
64_I	173_T	0.641	0.48
491_K	498_A	0.640	0.48
222_A	233_I	0.640	0.48
94_M	105_A	0.640	0.48
75_Q	113_V	0.639	0.48
552_I	560_F	0.639	0.48
457_H	462_L	0.639	0.48
53_I	57_V	0.638	0.48
98_D	102_R	0.637	0.48
407_E	412_F	0.637	0.48
350_V	372_V	0.636	0.48
357_V	368_K	0.636	0.48
348_Q	381_F	0.635	0.48
238_V	383_D	0.635	0.48
274_A	277_C	0.634	0.48
74_L	139_F	0.633	0.48
152_G	156_I	0.633	0.48
292_V	300_V	0.632	0.48
52_N	56_I	0.631	0.47
309_L	343_E	0.629	0.47
15_P	23_H	0.629	0.47
319_H	330_P	0.629	0.47
20_A	34_Q	0.629	0.47
328_T	332_F	0.628	0.47
199_S	206_D	0.627	0.47
492_L	530_V	0.627	0.47
530_V	534_A	0.626	0.47
291_L	342_V	0.623	0.47
37_S	147_F	0.623	0.47
59_E	183_N	0.620	0.46
89_Y	95_R	0.619	0.46
262_T	265_E	0.619	0.46
452_I	456_H	0.619	0.46
325_Q	328_T	0.619	0.46
233_I	386_F	0.618	0.46
424_A	435_P	0.617	0.46
73_A	105_A	0.617	0.46
164_H	176_K	0.616	0.46
119_R	422_M	0.615	0.46
326_L	330_P	0.615	0.46
479_N	482_N	0.615	0.46
432_R	520_D	0.614	0.46
23_H	34_Q	0.614	0.46
108_A	197_A	0.614	0.46
47_Y	485_Q	0.613	0.46
299_E	386_F	0.613	0.46
237_E	395_D	0.610	0.45
143_K	150_L	0.610	0.45
256_H	260_V	0.609	0.45
79_T	113_V	0.609	0.45
82_E	423_N	0.608	0.45
280_S	322_V	0.607	0.45
126_K	509_A	0.606	0.45
201_A	303_I	0.606	0.45
423_N	433_A	0.605	0.45
240_H	348_Q	0.604	0.45
228_Q	398_G	0.604	0.45
54_Q	58_R	0.603	0.44
62_E	65_D	0.602	0.44
179_E	186_A	0.602	0.44
7_L	67_V	0.601	0.44
63_K	180_A	0.599	0.44
294_V	349_A	0.598	0.44
262_T	296_G	0.598	0.44
151_R	412_F	0.597	0.44
531_G	538_I	0.595	0.44
64_I	160_A	0.595	0.44
281_V	291_L	0.595	0.44
461_G	544_R	0.595	0.44
150_L	214_S	0.594	0.43
278_I	372_V	0.594	0.43
58_R	62_E	0.593	0.43
19_E	34_Q	0.593	0.43
350_V	376_A	0.593	0.43
282_L	328_T	0.591	0.43
472_D	524_L	0.591	0.43
193_R	213_L	0.591	0.43
291_L	326_L	0.589	0.43
323_I	363_G	0.588	0.43
278_I	353_M	0.588	0.43
7_L	152_G	0.587	0.43
34_Q	143_K	0.585	0.43
99_R	141_D	0.585	0.43
542_K	547_G	0.584	0.42
343_E	379_K	0.584	0.42
122_V	128_L	0.583	0.42
290_V	314_V	0.583	0.42
330_P	333_V	0.582	0.42
27_L	221_I	0.582	0.42
471_Y	504_L	0.580	0.42
276_A	355_N	0.579	0.42
46_A	449_L	0.579	0.42
552_I	561_I	0.578	0.42
495_D	559_A	0.578	0.42
18_A	23_H	0.577	0.42
160_A	440_C	0.577	0.42
216_I	452_I	0.575	0.42
171_D	437_L	0.575	0.42
279_K	359_G	0.575	0.42
326_L	329_E	0.574	0.41
199_S	211_M	0.572	0.41
432_R	509_A	0.572	0.41
202_M	419_S	0.572	0.41
433_A	520_D	0.571	0.41
151_R	407_E	0.571	0.41
466_K	545_Q	0.569	0.41
416_T	419_S	0.569	0.41
89_Y	152_G	0.568	0.41
453_A	457_H	0.568	0.41
387_I	390_G	0.568	0.41
305_V	382_A	0.567	0.41
7_L	132_L	0.565	0.40
41_S	72_P	0.565	0.40
228_Q	397_K	0.564	0.40
543_I	547_G	0.564	0.40
157_M	412_F	0.563	0.40
372_V	378_I	0.562	0.40
188_C	211_M	0.560	0.40
319_H	322_V	0.560	0.40
413_K	437_L	0.560	0.40
71_M	75_Q	0.559	0.40
49_V	453_A	0.558	0.40
306_K	311_A	0.556	0.40
157_M	442_G	0.556	0.40
238_V	348_Q	0.554	0.39
63_K	498_A	0.554	0.39
372_V	379_K	0.554	0.39
289_F	520_D	0.553	0.39
427_L	433_A	0.552	0.39
288_R	341_D	0.552	0.39
497_K	501_Y	0.550	0.39
35_N	137_S	0.549	0.39
107_G	212_A	0.548	0.39
532_K	535_D	0.548	0.39
62_E	66_A	0.548	0.39
48_K	62_E	0.547	0.39
245_S	354_V	0.546	0.39
472_D	497_K	0.545	0.38
180_A	184_I	0.545	0.38
83_S	95_R	0.544	0.38
528_I	539_V	0.544	0.38
244_P	352_A	0.542	0.38
338_I	341_D	0.542	0.38
334_G	360_A	0.542	0.38
7_L	122_V	0.542	0.38
321_E	324_Q	0.542	0.38
59_E	81_Q	0.541	0.38
106_L	152_G	0.541	0.38
302_D	400_I	0.541	0.38
280_S	343_E	0.541	0.38
460_K	520_D	0.541	0.38
232_N	410_Q	0.541	0.38
258_P	296_G	0.540	0.38
92_E	100_H	0.540	0.38
246_D	249_P	0.539	0.38
107_G	134_Q	0.539	0.38
61_M	66_A	0.538	0.38
31_F	299_E	0.538	0.38
328_T	358_A	0.538	0.38
185_F	530_V	0.537	0.38
75_Q	202_M	0.537	0.38
9_P	45_L	0.537	0.38
89_Y	143_K	0.536	0.38
277_C	280_S	0.536	0.38
29_A	458_D	0.535	0.37
40_Y	406_I	0.535	0.37
166_S	437_L	0.535	0.37
361_N	366_H	0.534	0.37
282_L	326_L	0.534	0.37
168_E	172_E	0.534	0.37
322_V	333_V	0.533	0.37
80_W	84_G	0.533	0.37
11_L	510_E	0.533	0.37
199_S	205_K	0.532	0.37
190_I	451_A	0.532	0.37
55_Q	63_K	0.531	0.37
241_Q	352_A	0.530	0.37
285_A	290_V	0.530	0.37
495_D	558_S	0.529	0.37
115_T	440_C	0.528	0.37
19_E	102_R	0.527	0.37
20_A	450_S	0.527	0.37
263_I	331_G	0.527	0.37
149_L	453_A	0.526	0.37
200_G	412_F	0.526	0.37
185_F	448_T	0.526	0.37
359_G	366_H	0.526	0.37
260_V	358_A	0.525	0.36
67_V	515_K	0.525	0.36
257_T	263_I	0.525	0.36
252_L	368_K	0.525	0.36
7_L	282_L	0.524	0.36
106_L	117_L	0.523	0.36
320_E	323_I	0.523	0.36
78_E	102_R	0.523	0.36
15_P	18_A	0.522	0.36
13_E	456_H	0.521	0.36
46_A	156_I	0.521	0.36
263_I	366_H	0.520	0.36
199_S	307_N	0.520	0.36
533_R	549_S	0.520	0.36
42_Y	152_G	0.520	0.36
351_K	378_I	0.520	0.36
277_C	357_V	0.519	0.36
89_Y	108_A	0.519	0.36
26_L	51_Q	0.519	0.36
259_N	537_G	0.518	0.36
543_I	549_S	0.517	0.36
21_K	456_H	0.517	0.36
334_G	359_G	0.517	0.36
73_A	219_D	0.516	0.36
66_A	176_K	0.516	0.36
6_T	31_F	0.516	0.36
25_L	457_H	0.516	0.36
198_D	307_N	0.515	0.35
167_A	171_D	0.515	0.35
239_L	397_K	0.513	0.35
77_A	87_Y	0.513	0.35
168_E	491_K	0.513	0.35
422_M	436_M	0.512	0.35
83_S	201_A	0.512	0.35
137_S	219_D	0.512	0.35
259_N	363_G	0.512	0.35
151_R	200_G	0.510	0.35
64_I	212_A	0.510	0.35
144_R	407_E	0.510	0.35
418_Y	442_G	0.510	0.35
34_Q	105_A	0.510	0.35
222_A	235_M	0.509	0.35
211_M	437_L	0.509	0.35
258_P	269_F	0.508	0.35
319_H	329_E	0.508	0.35
35_N	116_S	0.506	0.35
331_G	359_G	0.506	0.35
428_D	432_R	0.506	0.35
222_A	389_E	0.506	0.35
490_E	493_Y	0.506	0.35
182_S	411_V	0.505	0.34
305_V	345_Y	0.505	0.34
73_A	139_F	0.505	0.34
281_V	334_G	0.505	0.34
526_I	529_T	0.505	0.34
221_I	235_M	0.504	0.34
489_A	528_I	0.504	0.34
407_E	442_G	0.504	0.34
193_R	228_Q	0.504	0.34
280_S	330_P	0.504	0.34
147_F	214_S	0.503	0.34
334_G	366_H	0.503	0.34
331_G	334_G	0.503	0.34
84_G	180_A	0.503	0.34
280_S	358_A	0.503	0.34
474_H	505_Y	0.503	0.34
107_G	136_Q	0.502	0.34
109_T	412_F	0.502	0.34
93_L	440_C	0.502	0.34
496_L	501_Y	0.502	0.34
143_K	147_F	0.501	0.34
66_A	177_M	0.500	0.34
266_L	366_H	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2j3lA	2	1	100	0.443	Contact Map
2i4lA	2	0.7748	100	0.534	Contact Map
4phcA	2	0.7784	100	0.65	Contact Map
4hvcA	2	0.6596	100	0.674	Contact Map
2zt5A	2	0.7181	100	0.678	Contact Map
1qf6A	1	0.7057	100	0.685	Contact Map
1nj8A	2	0.6454	100	0.691	Contact Map
3ialA	2	0.656	100	0.693	Contact Map
1nj1A	2	0.6418	100	0.699	Contact Map
4ncxA	2	0.6117	100	0.701	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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