GREMLIN Database
RIMM - Ribosome maturation factor RimM
UniProt: O31740 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 174 (163)
Sequences: 3819 (2870)
Seq/√Len: 224.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
110_E118_L3.5161.00
157_D160_E3.4931.00
112_F162_K2.7891.00
56_N68_Q2.6371.00
54_T70_K2.5581.00
114_E166_E2.4671.00
74_N77_E2.4171.00
123_K137_G2.3641.00
109_C161_K2.2751.00
112_F118_L2.2351.00
72_R78_V2.1261.00
39_T52_E2.0921.00
155_H164_E2.0641.00
109_C158_V2.0481.00
135_V143_D2.0231.00
14_T75_L1.9661.00
113_T117_E1.9361.00
54_T71_E1.8611.00
68_Q73_Q1.8511.00
122_V163_I1.8461.00
110_E121_K1.7581.00
56_N70_K1.7461.00
76_N79_E1.7431.00
20_E59_R1.7411.00
110_E162_K1.6901.00
7_N85_I1.6541.00
7_N87_K1.6421.00
53_V69_F1.6241.00
134_W148_Y1.6171.00
154_K166_E1.6131.00
138_R144_A1.6011.00
20_E68_Q1.5821.00
75_L79_E1.5421.00
29_F32_E1.5091.00
103_F125_I1.4871.00
111_V136_I1.4861.00
21_V69_F1.4801.00
13_N82_K1.4701.00
11_I21_V1.4391.00
90_E104_H1.3831.00
43_F85_I1.3741.00
10_K85_I1.3731.00
89_P92_E1.3471.00
23_V67_L1.3441.00
103_F127_T1.3351.00
14_T79_E1.3311.00
79_E82_K1.3311.00
149_I152_V1.3151.00
112_F164_E1.2961.00
43_F87_K1.2801.00
77_E80_E1.2701.00
127_T132_D1.2651.00
111_V165_I1.2551.00
15_H66_L1.2541.00
10_K24_I1.2341.00
73_Q77_E1.2171.00
107_I124_E1.2051.00
109_C163_I1.1981.00
97_N100_E1.1911.00
14_T82_K1.1831.00
157_D162_K1.1811.00
118_L139_K1.1591.00
146_I165_I1.1581.00
43_F84_A1.1551.00
99_G150_E1.1481.00
42_L84_A1.1421.00
41_Y52_E1.1371.00
105_E158_V1.1291.00
21_V67_L1.1281.00
114_E154_K1.1251.00
72_R81_L1.1221.00
126_L135_V1.1171.00
124_E135_V1.1091.00
94_G102_Y1.1041.00
61_H66_L1.1011.00
50_P87_K1.0901.00
22_R64_F1.0781.00
44_M84_A1.0771.00
134_W163_I1.0731.00
113_T167_L1.0671.00
17_I76_N1.0591.00
17_I75_L1.0541.00
40_L55_V1.0491.00
122_V134_W1.0491.00
21_V78_V1.0321.00
138_R143_D1.0301.00
118_L121_K1.0281.00
12_V24_I1.0261.00
5_W89_P1.0191.00
128_P131_N1.0111.00
13_N22_R1.0051.00
121_K137_G0.9971.00
42_L53_V0.9891.00
137_G143_D0.9841.00
5_W41_Y0.9841.00
27_T33_R0.9841.00
39_T54_T0.9831.00
12_V82_K0.9691.00
20_E57_T0.9641.00
93_L102_Y0.9511.00
93_L104_H0.9491.00
9_G23_V0.9391.00
126_L133_V0.9251.00
43_F50_P0.9241.00
29_F33_R0.9120.99
90_E105_E0.9050.99
42_L86_I0.9030.99
57_T68_Q0.8950.99
136_I146_I0.8880.99
6_F90_E0.8860.99
128_P133_V0.8860.99
106_I122_V0.8830.99
44_M51_V0.8750.99
131_N149_I0.8740.99
122_V148_Y0.8710.99
10_K26_K0.8650.99
106_I134_W0.8630.99
58_H65_H0.8630.99
12_V22_R0.8600.99
25_S65_H0.8540.99
149_I168_M0.8430.99
96_L100_E0.8370.99
90_E93_L0.8340.99
44_M49_E0.8280.99
108_G121_K0.8280.99
60_L65_H0.8260.99
101_F148_Y0.8250.99
135_V145_L0.8250.99
111_V146_I0.8240.99
53_V86_I0.8190.99
15_H22_R0.8180.99
158_V161_K0.8180.99
15_H20_E0.8110.99
133_V145_L0.8060.99
40_L86_I0.8030.99
12_V83_N0.7910.99
146_I152_V0.7910.99
139_K142_K0.7900.98
37_G40_L0.7880.98
113_T119_I0.7830.98
17_I74_N0.7810.98
95_E98_E0.7800.98
40_L53_V0.7750.98
116_G164_E0.7670.98
4_R90_E0.7470.98
155_H162_K0.7400.98
123_K143_D0.7350.98
131_N152_V0.7350.98
133_V152_V0.7320.98
23_V86_I0.7300.97
6_F93_L0.7240.97
20_E66_L0.7210.97
156_I163_I0.7210.97
11_I69_F0.7180.97
123_K135_V0.7150.97
28_D33_R0.7130.97
26_K85_I0.7120.97
39_T92_E0.7030.97
24_I64_F0.7030.97
153_V165_I0.6960.97
136_I152_V0.6900.96
138_R142_K0.6860.96
34_Y37_G0.6840.96
112_F116_G0.6830.96
9_G34_Y0.6780.96
6_F102_Y0.6680.96
138_R141_K0.6660.96
77_E81_L0.6620.96
167_L170_G0.6600.95
59_R66_L0.6530.95
152_V167_L0.6480.95
53_V72_R0.6450.95
106_I109_C0.6450.95
110_E161_K0.6440.95
35_K58_H0.6440.95
35_K60_L0.6430.95
40_L69_F0.6420.95
148_Y163_I0.6400.95
76_N80_E0.6370.95
148_Y153_V0.6330.94
114_E164_E0.6310.94
6_F104_H0.6300.94
11_I23_V0.6290.94
36_P95_E0.6210.94
10_K83_N0.6200.94
33_R36_P0.6180.94
15_H59_R0.6170.94
93_L105_E0.6130.93
101_F158_V0.6130.93
41_Y92_E0.6100.93
50_P84_A0.6050.93
151_S166_E0.6040.93
11_I42_L0.5980.92
41_Y50_P0.5900.92
5_W87_K0.5880.92
133_V149_I0.5880.92
99_G105_E0.5840.92
113_T165_I0.5790.91
43_F48_N0.5720.91
146_I153_V0.5690.91
125_I134_W0.5660.90
21_V81_L0.5650.90
55_V58_H0.5650.90
78_V81_L0.5640.90
30_A34_Y0.5610.90
119_I167_L0.5600.90
4_R89_P0.5600.90
148_Y156_I0.5530.89
41_Y87_K0.5500.89
151_S168_M0.5470.89
55_V67_L0.5460.89
27_T30_A0.5460.89
137_G141_K0.5440.88
33_R37_G0.5410.88
144_A168_M0.5410.88
35_K38_N0.5410.88
126_L145_L0.5380.88
101_F156_I0.5360.88
132_D152_V0.5350.88
21_V82_K0.5340.88
8_V40_L0.5320.87
122_V125_I0.5320.87
7_N10_K0.5310.87
23_V58_H0.5310.87
164_E167_L0.5300.87
113_T116_G0.5280.87
130_A149_I0.5270.87
75_L78_V0.5260.87
8_V33_R0.5250.87
36_P98_E0.5240.87
8_V34_Y0.5240.87
72_R77_E0.5220.86
22_R61_H0.5220.86
32_E35_K0.5210.86
152_V168_M0.5180.86
9_G26_K0.5160.86
109_C156_I0.5150.86
102_Y105_E0.5150.86
51_V72_R0.5140.86
154_K164_E0.5110.85
44_M50_P0.5100.85
56_N73_Q0.5080.85
147_P152_V0.5020.84
11_I84_A0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3h9nA 3 0.9655 100 0.058 Contact Map
2qggA 1 0.9598 100 0.083 Contact Map
2f1lA 2 0.9195 100 0.084 Contact Map
2dyiA 1 0.9023 100 0.138 Contact Map
3htrA 2 0.4598 96.6 0.853 Contact Map
1eysH 1 0.8506 82.9 0.902 Contact Map
1rzhH 1 0.908 80.3 0.904 Contact Map
1vx79 1 0.2529 76.6 0.908 Contact Map
1pm3A 2 0.3851 73.6 0.91 Contact Map
4a18H 1 0.2701 68.1 0.913 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.007 seconds.