GREMLIN Database
YLQD - Uncharacterized protein YlqD
UniProt: O31739 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 128 (124)
Sequences: 289 (210)
Seq/√Len: 18.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
118_K123_I4.4491.00
6_R95_D3.1050.99
22_L77_I2.9930.99
16_R19_E2.9450.99
18_K85_L2.6600.98
88_E126_R2.4900.97
114_T126_R2.4570.96
86_G124_E2.4520.96
62_A66_R2.3790.96
79_Q87_S2.1250.92
86_G118_K2.0810.91
9_V39_L2.0690.91
76_Q104_D2.0290.90
4_I95_D2.0260.90
13_L18_K1.9210.87
44_R122_V1.9150.87
11_Q91_E1.8460.85
35_E66_R1.8330.85
12_V118_K1.8170.84
3_I94_V1.7100.80
9_V92_K1.6100.76
2_Q97_L1.5770.75
76_Q79_Q1.5560.74
20_K120_G1.5470.73
70_I74_D1.5190.72
43_L59_F1.5160.71
35_E62_A1.5020.71
10_M114_T1.4640.69
13_L89_L1.4400.67
11_Q17_S1.3920.65
9_V84_P1.3640.63
107_H122_V1.3350.61
75_F79_Q1.3310.61
51_Q55_M1.3290.61
101_E104_D1.2860.58
62_A65_K1.2430.56
56_I116_V1.2330.55
22_L26_A1.2290.55
52_N60_K1.2270.55
13_L106_W1.2200.54
37_S98_L1.1790.52
42_Q72_I1.1560.50
6_R86_G1.1520.50
21_L39_L1.1490.50
28_K63_I1.1470.50
3_I122_V1.1250.48
76_Q122_V1.1190.48
42_Q114_T1.1000.47
20_K68_D1.0850.46
23_A85_L1.0750.45
61_K100_I1.0580.44
42_Q93_E1.0470.43
105_D108_E1.0460.43
45_K51_Q1.0410.43
121_K125_I1.0210.42
102_A124_E0.9920.40
80_V97_L0.9810.39
21_L83_L0.9790.39
38_Q79_Q0.9760.39
3_I9_V0.9720.39
11_Q59_F0.9550.38
25_F113_N0.9540.38
42_Q126_R0.9490.38
19_E23_A0.9450.37
21_L97_L0.9410.37
15_E99_T0.9400.37
30_Q122_V0.9320.37
8_A90_K0.9310.36
45_K90_K0.9270.36
6_R90_K0.9270.36
5_H96_A0.9190.36
35_E87_S0.9170.36
10_M88_E0.9070.35
121_K124_E0.9000.35
79_Q84_P0.8880.34
29_K32_L0.8880.34
25_F107_H0.8800.34
13_L126_R0.8740.33
105_D121_K0.8710.33
55_M89_L0.8700.33
30_Q77_I0.8660.33
12_V116_V0.8550.32
16_R115_I0.8540.32
92_K110_T0.8540.32
66_R86_G0.8530.32
94_V116_V0.8440.32
38_Q69_D0.8440.32
30_Q116_V0.8220.30
79_Q93_E0.8220.30
84_P93_E0.8190.30
12_V86_G0.8180.30
74_D123_I0.8160.30
41_F115_I0.8030.29
33_E70_I0.7990.29
31_M101_E0.7980.29
63_I67_K0.7960.29
4_I97_L0.7940.29
25_F40_Y0.7920.29
39_L59_F0.7910.29
16_R119_D0.7800.28
27_E123_I0.7790.28
89_L123_I0.7780.28
78_A85_L0.7760.28
90_K112_A0.7670.28
27_E65_K0.7550.27
25_F29_K0.7520.27
41_F48_K0.7460.26
50_Q55_M0.7410.26
10_M81_H0.7400.26
76_Q84_P0.7350.26
19_E54_N0.7350.26
31_M95_D0.7310.26
37_S44_R0.7310.26
38_Q76_Q0.7290.26
26_A78_A0.7270.26
17_S106_W0.7250.25
87_S102_A0.7230.25
75_F78_A0.7220.25
99_T115_I0.7160.25
65_K123_I0.7160.25
46_H55_M0.7110.25
67_K100_I0.7040.24
25_F36_C0.6980.24
32_L80_V0.6960.24
41_F62_A0.6910.24
57_E102_A0.6900.24
8_A30_Q0.6870.24
33_E54_N0.6830.24
55_M100_I0.6830.24
46_H108_E0.6780.23
21_L62_A0.6760.23
7_V12_V0.6730.23
15_E19_E0.6710.23
42_Q71_K0.6690.23
104_D122_V0.6540.22
39_L62_A0.6540.22
12_V123_I0.6530.22
44_R93_E0.6520.22
43_L58_Q0.6500.22
5_H25_F0.6490.22
36_C65_K0.6480.22
18_K54_N0.6470.22
10_M118_K0.6430.22
35_E47_E0.6330.21
36_C70_I0.6240.21
46_H117_I0.6180.21
42_Q49_E0.6170.21
81_H123_I0.6170.21
51_Q56_I0.6170.21
33_E37_S0.6100.20
3_I73_I0.6070.20
49_E124_E0.6050.20
36_C101_E0.6020.20
104_D126_R0.6000.20
55_M76_Q0.5970.20
27_E105_D0.5950.20
26_A33_E0.5930.20
40_Y74_D0.5920.20
21_L40_Y0.5860.19
80_V96_A0.5800.19
62_A68_D0.5750.19
65_K118_K0.5700.19
74_D96_A0.5690.19
97_L102_A0.5670.19
43_L95_D0.5640.19
23_A26_A0.5630.19
9_V117_I0.5590.18
17_S44_R0.5550.18
8_A89_L0.5530.18
22_L80_V0.5510.18
36_C110_T0.5510.18
38_Q68_D0.5480.18
7_V96_A0.5460.18
84_P87_S0.5450.18
52_N102_A0.5440.18
21_L41_F0.5430.18
43_L48_K0.5350.17
6_R32_L0.5330.17
42_Q78_A0.5320.17
33_E60_K0.5220.17
59_F80_V0.5150.17
41_F45_K0.5130.17
99_T102_A0.5030.16
24_S114_T0.5030.16
3_I109_K0.5020.16
82_T92_K0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4dciA 3 0.9844 100 0.089 Contact Map
3ghgA 2 0.6172 21.1 0.927 Contact Map
4kisA 2 0.9609 12.7 0.934 Contact Map
1gaxA 1 0.6328 9.7 0.937 Contact Map
3kinB 2 0.375 9.5 0.938 Contact Map
2c41A 6 0.8906 9.3 0.938 Contact Map
2yw6A 6 0.875 9.1 0.938 Contact Map
3kwoA 6 0.8594 8.9 0.939 Contact Map
1deqA 1 0.7812 8.4 0.939 Contact Map
2xgwA 6 0.9375 7.6 0.94 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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