GREMLIN Database
YLQC - UPF0109 protein YlqC
UniProt: O31738 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 81 (75)
Sequences: 831 (533)
Seq/√Len: 61.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_V77_F3.6591.00
11_V15_T3.2681.00
14_V39_L3.1531.00
57_A79_I2.9941.00
23_D42_H2.8821.00
10_I37_L2.5341.00
7_E11_V2.5151.00
39_L77_F2.3151.00
20_H23_D2.2811.00
7_E28_R2.0451.00
20_H42_H1.9051.00
29_E38_R1.8671.00
25_R40_S1.7350.99
41_V49_V1.7070.99
19_D48_K1.6870.99
12_H16_P1.5640.99
10_I64_V1.5370.99
15_T24_I1.4680.98
27_I38_R1.3860.97
34_K76_Q1.3830.97
36_A76_Q1.3620.97
30_E73_K1.2470.95
14_V26_V1.2330.94
46_T65_F1.2230.94
10_I77_F1.2140.94
38_R80_F1.2010.93
53_Q58_K1.1460.92
14_V60_I1.0800.89
18_V24_I1.0740.89
46_T56_T1.0740.89
29_E33_Q1.0710.89
68_G75_V1.0640.89
46_T60_I1.0620.88
39_L79_I1.0580.88
63_A66_A1.0530.88
39_L64_V1.0280.87
42_H65_F1.0270.87
65_F77_F1.0160.86
52_K74_K0.9790.84
37_L64_V0.9700.83
14_V57_A0.8880.78
66_A79_I0.8870.78
13_I63_A0.8640.76
7_E37_L0.8540.75
6_L13_I0.8440.74
13_I39_L0.8430.74
10_I16_P0.8430.74
62_T80_F0.8410.74
31_T34_K0.8390.73
67_A77_F0.8360.73
20_H44_S0.7700.67
63_A68_G0.7420.64
9_L17_L0.7290.63
52_K69_V0.7280.63
65_F74_K0.7250.62
58_K78_E0.7200.62
17_L23_D0.7070.60
45_D66_A0.7030.60
11_V66_A0.6900.58
35_I70_Q0.6690.56
8_D79_I0.6680.56
26_V80_F0.6640.56
38_R48_K0.6620.55
55_R65_F0.6620.55
23_D30_E0.6550.55
15_T21_P0.6540.54
49_V79_I0.6530.54
25_R28_R0.6530.54
12_H59_A0.6450.53
9_L48_K0.6390.53
68_G71_S0.6370.52
40_S70_Q0.6300.52
12_H56_T0.6280.51
57_A62_T0.6260.51
33_Q74_K0.6210.51
13_I58_K0.6200.51
6_L71_S0.6180.50
19_D44_S0.6140.50
25_R44_S0.6010.48
17_L66_A0.5970.48
24_I39_L0.5890.47
35_I75_V0.5820.46
25_R29_E0.5810.46
9_L63_A0.5800.46
31_T78_E0.5800.46
36_A63_A0.5780.46
76_Q80_F0.5770.46
34_K38_R0.5760.46
53_Q70_Q0.5720.45
31_T38_R0.5710.45
39_L57_A0.5710.45
26_V37_L0.5700.45
8_D11_V0.5580.44
48_K79_I0.5560.43
65_F76_Q0.5530.43
18_V41_V0.5520.43
17_L53_Q0.5440.42
56_T79_I0.5440.42
23_D44_S0.5390.41
56_T75_V0.5340.41
19_D78_E0.5330.41
32_D72_S0.5330.41
26_V41_V0.5250.40
13_I52_K0.5200.39
36_A78_E0.5190.39
52_K59_A0.5140.39
9_L65_F0.5110.38
68_G77_F0.5030.38
55_R58_K0.5020.37
6_L78_E0.5010.37
12_H52_K0.5000.37
10_I65_F0.5000.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gkuA 2 0.963 99.3 0.571 Contact Map
2pt7G 2 0.9506 99.2 0.603 Contact Map
2cxcA 1 0.8148 98.1 0.721 Contact Map
2jzxA 1 0.5185 93.1 0.828 Contact Map
2axyA 2 0.5185 92.2 0.833 Contact Map
2anrA 1 0.5926 92.1 0.834 Contact Map
1j4wA 1 0.4938 90.6 0.84 Contact Map
2p2rA 1 0.4938 90.5 0.84 Contact Map
1zzkA 1 0.5185 90.4 0.841 Contact Map
2jvzA 1 0.5802 90.2 0.841 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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