GREMLIN Database
YLMG - Uncharacterized membrane protein YlmG
UniProt: O31729 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 90 (80)
Sequences: 1588 (1132)
Seq/√Len: 126.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_Y46_C3.0891.00
53_F70_A3.0441.00
47_E51_E2.8941.00
20_A46_C2.4641.00
60_I65_I2.3271.00
68_I75_R2.3051.00
20_A45_I2.0851.00
14_I78_T2.0501.00
21_L46_C2.0421.00
14_I74_L2.0041.00
11_S78_T1.9571.00
52_P56_I1.9311.00
53_F73_V1.8391.00
59_P62_M1.8331.00
21_L70_A1.8171.00
47_E54_R1.6381.00
40_R44_S1.6381.00
75_R78_T1.5761.00
20_A42_L1.5141.00
54_R64_D1.4661.00
11_S15_T1.4221.00
76_F80_G1.3961.00
41_F45_I1.3751.00
49_Y70_A1.3611.00
54_R59_P1.3061.00
68_I71_I1.2461.00
72_L79_T1.1920.99
15_T78_T1.1630.99
22_I71_I1.1600.99
49_Y52_P1.1280.99
29_W63_L1.1210.99
15_T19_F1.1150.99
50_L67_P1.1090.99
10_L85_Y1.0940.99
18_S75_R1.0890.99
19_F23_I1.0880.99
7_F82_W1.0570.98
79_T83_G0.9850.98
7_F85_Y0.9790.97
75_R79_T0.9760.97
10_L18_S0.9410.97
26_F75_R0.9200.96
30_V33_T0.9040.96
18_S74_L0.8990.96
59_P65_I0.8950.96
50_L70_A0.8760.95
22_I74_L0.8690.95
13_L17_Y0.8580.95
33_T39_G0.8480.94
17_Y74_L0.8480.94
24_Y50_L0.8360.94
31_P39_G0.8230.93
72_L76_F0.8230.93
80_G83_G0.8200.93
59_P64_D0.8200.93
8_S12_L0.8150.93
25_I68_I0.8110.93
12_L16_I0.8070.93
30_V58_P0.7970.92
25_I62_M0.7970.92
25_I67_P0.7850.92
15_T75_R0.7840.92
57_I69_V0.7670.91
58_P66_S0.7630.90
56_I61_A0.7620.90
27_M36_T0.7590.90
50_L66_S0.7580.90
33_T36_T0.7580.90
21_L71_I0.7540.90
82_W85_Y0.7490.90
78_T82_W0.7390.89
15_T38_V0.7380.89
27_M39_G0.7360.89
24_Y47_E0.7330.89
76_F79_T0.7330.89
25_I29_W0.6950.86
61_A65_I0.6870.85
80_G84_L0.6790.84
17_Y48_P0.6760.84
21_L50_L0.6640.83
16_I20_A0.6610.83
65_I68_I0.6560.82
62_M65_I0.6520.82
40_R43_A0.6450.81
25_I59_P0.6450.81
30_V42_L0.6370.80
71_I75_R0.6370.80
11_S14_I0.6360.80
28_S64_D0.6360.80
60_I66_S0.6360.80
57_I60_I0.6280.80
55_K58_P0.6280.80
15_T18_S0.6230.79
26_F38_V0.6190.79
17_Y45_I0.6180.78
29_W65_I0.6110.78
60_I77_A0.6100.78
24_Y43_A0.6070.77
49_Y53_F0.6000.76
57_I61_A0.5980.76
7_F10_L0.5920.75
24_Y39_G0.5880.75
35_E40_R0.5670.72
28_S67_P0.5590.71
26_F33_T0.5540.71
52_P80_G0.5530.70
16_I55_K0.5510.70
17_Y20_A0.5470.70
30_V62_M0.5460.70
34_R76_F0.5460.70
69_V73_V0.5460.70
15_T63_L0.5390.69
33_T37_A0.5360.68
58_P69_V0.5310.67
49_Y56_I0.5260.67
33_T40_R0.5140.65
58_P61_A0.5080.64
19_F29_W0.5070.64
74_L78_T0.5010.63
49_Y77_A0.5000.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ku5A 2 0.5 3.4 0.914 Contact Map
3tiaA 3 0 3.1 0.916 Contact Map
1nmbN 1 0 2.7 0.918 Contact Map
4b7jA 3 0 1.6 0.928 Contact Map
1ciiA 1 0.4667 1.3 0.932 Contact Map
2mm4A 1 0.3556 1 0.937 Contact Map
4p6vD 1 0.8556 0.9 0.938 Contact Map
2lotA 1 0.3667 0.9 0.938 Contact Map
4lxjA 1 0.4889 0.8 0.94 Contact Map
4pirA 3 0.3111 0.8 0.941 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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