YKNV - BACSU - GREMLIN Contacts

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YKNV - Uncharacterized ABC transporter ATP-binding protein YknV

UniProt:	O31708	Sequences: MKQAKKQGVLERFYYSSDEIIEKPFNWAQMWRLLSYVKPYRKTILPLSFLTVLIGTAVKLVIPILIGVYVLDQAITGRNSELLIQLIFIISGLYVLNYAANVLRIRWMNQLGQHVIYDLRQHLFTHVQRLSHRFFDQRSAGSILVRIMNDINSLQELFTSGVINLLTDLLLLAGVIIILFTLSPELTIAIMVTLPIMFFISTSLRKKIRRSWQTVRLKQSKLNSHLNESIQGIRVTQAFTQEEENMAYFDGVNQENYESWREATRKNAMFRPLVEMTNAIGTAVLIWYGATLIMNETITIGVFVSFAFYLGMFWEPISRLGQVYNQLLMGMASSERIFEFLDEQPNVKEKPNAIHNEKINGEISFEEVEFSYDEKRKALHAVSFSIPAGSTLALVGHTGSGKTTIANLISRFYDAAGGTIKIDGIPIKDLSLASLRSQISIVLQDTFIFSGTIMENIRFGRPNASDEEVMKASQAVGADEFISDLAEGYATEVEERGSVLSAGQRQLISFARALLADPAIIILDEATASIDTETEVKIQQALKTLLKGRTAVMIAHRLSTIRDADRIIVLDHGRKIEEGNHDQLLAKGGIYAGLVKAQYSTAIE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	604 (564)
Sequences:	52744 (37426)
Seq/√Len:	1575.9

ECOLI - MSBA MDLA CYDD MDLB CYDC YOJI YDDA
BACSU - YKNV YFIC YHEH SUNT YGAD BMRA YKNU YWJA YFIB YHEI CYDD CYDC YVRA OPUAA
HALSA - Q9HSQ7 Q9HMX3 BTUDA Q9HMW0
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
479_D	489_Y	4.494	1.00
364_S	385_S	4.380	1.00
387_P	390_S	4.260	1.00
390_S	566_R	4.255	1.00
367_E	381_A	4.220	1.00
566_R	578_E	4.014	1.00
451_G	455_E	3.946	1.00
366_E	419_T	3.849	1.00
454_M	466_D	3.847	1.00
474_Q	479_D	3.824	1.00
581_H	591_Y	3.821	1.00
362_E	385_S	3.490	1.00
366_E	421_K	3.489	1.00
479_D	483_S	3.441	1.00
419_T	426_P	3.289	1.00
380_H	574_R	3.098	1.00
454_M	490_A	3.019	1.00
454_M	458_R	2.975	1.00
466_D	470_M	2.920	1.00
365_F	368_V	2.918	1.00
465_S	468_E	2.908	1.00
588_G	592_A	2.895	1.00
377_K	380_H	2.878	1.00
592_A	596_K	2.872	1.00
473_S	489_Y	2.826	1.00
406_A	554_I	2.738	1.00
369_E	381_A	2.731	1.00
406_A	522_I	2.643	1.00
364_S	421_K	2.580	1.00
577_E	587_K	2.579	1.00
438_Q	519_A	2.557	1.00
471_K	475_A	2.542	1.00
362_E	387_P	2.433	1.00
470_M	479_D	2.424	1.00
371_S	377_K	2.388	1.00
457_I	473_S	2.379	1.00
517_D	549_R	2.370	1.00
580_N	583_Q	2.362	1.00
568_I	578_E	2.358	1.00
386_I	392_L	2.337	1.00
411_R	414_D	2.326	1.00
487_E	491_T	2.301	1.00
177_I	181_T	2.296	1.00
454_M	469_V	2.286	1.00
431_S	434_S	2.275	1.00
369_E	377_K	2.261	1.00
369_E	417_G	2.258	1.00
440_S	518_P	2.251	1.00
577_E	589_G	2.245	1.00
461_R	468_E	2.243	1.00
577_E	588_G	2.209	1.00
391_T	564_A	2.147	1.00
72_D	301_G	2.133	1.00
362_E	388_A	2.123	1.00
384_F	568_I	2.107	1.00
571_D	590_I	2.101	1.00
470_M	474_Q	2.099	1.00
478_A	481_F	2.042	1.00
32_R	342_D	2.027	1.00
457_I	469_V	2.019	1.00
543_K	563_D	2.003	1.00
535_E	557_R	1.968	1.00
365_F	384_F	1.951	1.00
386_I	552_V	1.946	1.00
414_D	428_K	1.935	1.00
468_E	517_D	1.928	1.00
126_H	345_P	1.923	1.00
371_S	416_A	1.920	1.00
36_Y	122_H	1.909	1.00
470_M	483_S	1.888	1.00
367_E	383_S	1.879	1.00
84_I	88_F	1.876	1.00
361_G	423_D	1.876	1.00
579_G	583_Q	1.875	1.00
218_K	255_E	1.867	1.00
72_D	299_T	1.863	1.00
472_A	476_V	1.801	1.00
338_F	342_D	1.791	1.00
183_S	292_L	1.785	1.00
392_L	566_R	1.779	1.00
40_Y	118_D	1.773	1.00
458_R	469_V	1.744	1.00
576_I	590_I	1.734	1.00
571_D	576_I	1.728	1.00
392_L	568_I	1.723	1.00
471_K	474_Q	1.712	1.00
405_I	570_L	1.712	1.00
466_D	490_A	1.701	1.00
458_R	466_D	1.692	1.00
38_K	41_R	1.687	1.00
568_I	575_K	1.687	1.00
241_Q	244_E	1.670	1.00
477_G	537_K	1.668	1.00
390_S	565_D	1.662	1.00
393_A	564_A	1.655	1.00
363_I	552_V	1.634	1.00
391_T	553_M	1.634	1.00
475_A	544_T	1.628	1.00
536_V	540_Q	1.625	1.00
530_I	538_I	1.616	1.00
150_D	336_R	1.604	1.00
585_L	595_V	1.602	1.00
360_N	423_D	1.597	1.00
494_E	499_V	1.592	1.00
426_P	429_D	1.583	1.00
291_T	295_N	1.578	1.00
88_F	92_G	1.575	1.00
464_A	515_L	1.561	1.00
493_V	500_L	1.552	1.00
457_I	515_L	1.543	1.00
394_L	568_I	1.539	1.00
473_S	482_I	1.535	1.00
362_E	423_D	1.533	1.00
468_E	471_K	1.523	1.00
470_M	489_Y	1.516	1.00
213_Q	335_E	1.509	1.00
583_Q	587_K	1.507	1.00
480_E	483_S	1.501	1.00
129_R	345_P	1.497	1.00
180_F	187_T	1.486	1.00
394_L	405_I	1.476	1.00
577_E	592_A	1.474	1.00
221_K	255_E	1.461	1.00
85_Q	89_I	1.459	1.00
487_E	492_E	1.445	1.00
387_P	566_R	1.441	1.00
562_R	582_D	1.441	1.00
379_L	382_V	1.439	1.00
67_G	305_S	1.423	1.00
467_E	470_M	1.421	1.00
555_A	560_T	1.419	1.00
225_H	252_V	1.415	1.00
287_W	291_T	1.410	1.00
126_H	130_L	1.405	1.00
410_S	441_I	1.403	1.00
473_S	479_D	1.399	1.00
368_V	415_A	1.395	1.00
590_I	593_G	1.391	1.00
365_F	409_I	1.380	1.00
370_F	404_T	1.372	1.00
540_Q	544_T	1.360	1.00
582_D	586_A	1.356	1.00
214_T	259_S	1.353	1.00
408_L	420_I	1.351	1.00
450_S	492_E	1.340	1.00
397_H	571_D	1.338	1.00
544_T	547_K	1.336	1.00
466_D	469_V	1.333	1.00
370_F	408_L	1.328	1.00
381_A	574_R	1.327	1.00
481_F	504_Q	1.322	1.00
180_F	184_P	1.319	1.00
63_P	309_Y	1.314	1.00
218_K	259_S	1.306	1.00
440_S	513_A	1.305	1.00
207_K	210_R	1.294	1.00
349_E	431_S	1.292	1.00
361_G	388_A	1.290	1.00
468_E	515_L	1.288	1.00
370_F	413_Y	1.284	1.00
218_K	221_K	1.278	1.00
359_I	423_D	1.268	1.00
245_N	459_F	1.263	1.00
425_I	429_D	1.258	1.00
393_A	561_I	1.258	1.00
366_E	383_S	1.253	1.00
458_R	464_A	1.251	1.00
397_H	590_I	1.245	1.00
485_L	491_T	1.240	1.00
369_E	380_H	1.236	1.00
126_H	341_L	1.231	1.00
292_L	297_T	1.228	1.00
467_E	471_K	1.228	1.00
475_A	514_L	1.226	1.00
51_T	100_A	1.221	1.00
546_L	551_A	1.215	1.00
398_T	534_T	1.213	1.00
199_F	203_S	1.211	1.00
409_I	552_V	1.198	1.00
362_E	424_G	1.192	1.00
186_L	306_F	1.189	1.00
229_S	245_N	1.189	1.00
481_F	485_L	1.186	1.00
35_S	38_K	1.183	1.00
299_T	302_V	1.179	1.00
461_R	464_A	1.178	1.00
453_I	508_I	1.178	1.00
384_F	405_I	1.175	1.00
121_Q	125_T	1.173	1.00
478_A	482_I	1.169	1.00
506_Q	528_A	1.169	1.00
179_L	306_F	1.167	1.00
392_L	552_V	1.166	1.00
60_L	174_G	1.164	1.00
473_S	478_A	1.164	1.00
32_R	338_F	1.163	1.00
254_Q	258_E	1.158	1.00
247_A	251_G	1.157	1.00
237_Q	242_E	1.154	1.00
484_D	504_Q	1.147	1.00
382_V	405_I	1.144	1.00
415_A	427_I	1.138	1.00
470_M	473_S	1.135	1.00
243_E	247_A	1.134	1.00
360_N	388_A	1.132	1.00
377_K	416_A	1.131	1.00
388_A	519_A	1.130	1.00
425_I	430_L	1.130	1.00
483_S	488_G	1.125	1.00
494_E	497_G	1.124	1.00
567_I	581_H	1.120	1.00
64_I	68_V	1.119	1.00
465_S	515_L	1.119	1.00
39_P	118_D	1.119	1.00
232_G	447_F	1.116	1.00
500_L	508_I	1.115	1.00
472_A	514_L	1.115	1.00
136_D	413_Y	1.114	1.00
432_L	436_R	1.112	1.00
477_G	534_T	1.102	1.00
142_S	220_S	1.098	1.00
123_L	340_F	1.095	1.00
221_K	252_V	1.090	1.00
138_R	142_S	1.089	1.00
211_S	262_E	1.084	1.00
480_E	484_D	1.080	1.00
54_I	100_A	1.079	1.00
365_F	420_I	1.079	1.00
386_I	550_T	1.075	1.00
193_T	281_G	1.072	1.00
125_T	129_R	1.070	1.00
476_V	511_A	1.068	1.00
126_H	129_R	1.066	1.00
442_V	513_A	1.064	1.00
391_T	551_A	1.064	1.00
139_S	142_S	1.062	1.00
581_H	585_L	1.059	1.00
367_E	417_G	1.055	1.00
334_S	338_F	1.051	1.00
588_G	596_K	1.050	1.00
350_K	353_A	1.048	1.00
365_F	405_I	1.043	1.00
110_Q	114_H	1.042	1.00
477_G	540_Q	1.038	1.00
569_V	590_I	1.037	1.00
118_D	122_H	1.036	1.00
446_T	509_S	1.033	1.00
408_L	415_A	1.030	1.00
434_S	437_S	1.030	1.00
245_N	248_Y	1.029	1.00
363_I	409_I	1.028	1.00
288_Y	292_L	1.022	1.00
422_I	435_L	1.018	1.00
251_G	255_E	1.016	1.00
185_E	297_T	1.016	1.00
553_M	564_A	1.016	1.00
513_A	521_I	1.008	1.00
372_Y	378_A	1.008	1.00
249_F	253_N	0.999	1.00
257_Y	261_R	0.997	1.00
555_A	561_I	0.995	1.00
188_I	192_V	0.995	1.00
65_L	86_L	0.992	1.00
477_G	541_A	0.990	1.00
525_E	556_H	0.988	1.00
377_K	417_G	0.988	1.00
289_G	303_F	0.987	1.00
136_D	407_N	0.987	1.00
153_S	333_S	0.986	1.00
262_E	265_R	0.986	1.00
225_H	248_Y	0.986	1.00
51_T	103_L	0.983	1.00
455_E	458_R	0.982	1.00
290_A	294_M	0.981	1.00
173_A	177_I	0.977	1.00
350_K	429_D	0.976	1.00
537_K	540_Q	0.976	1.00
203_S	207_K	0.976	1.00
236_T	245_N	0.972	1.00
184_P	188_I	0.970	1.00
477_G	544_T	0.966	1.00
521_I	549_R	0.965	1.00
244_E	248_Y	0.965	1.00
31_W	35_S	0.963	1.00
420_I	427_I	0.962	1.00
364_S	424_G	0.958	1.00
471_K	517_D	0.957	1.00
390_S	578_E	0.956	1.00
241_Q	245_N	0.955	1.00
469_V	489_Y	0.949	1.00
213_Q	217_L	0.942	1.00
487_E	490_A	0.942	1.00
248_Y	252_V	0.941	1.00
38_K	42_K	0.940	1.00
393_A	555_A	0.938	1.00
533_E	537_K	0.938	1.00
454_M	470_M	0.937	1.00
519_A	549_R	0.934	1.00
368_V	408_L	0.933	1.00
472_A	515_L	0.931	1.00
398_T	507_L	0.931	1.00
48_S	108_M	0.930	1.00
117_Y	121_Q	0.929	1.00
250_D	254_Q	0.928	1.00
207_K	266_K	0.927	1.00
411_R	432_L	0.927	1.00
482_I	489_Y	0.926	1.00
403_T	407_N	0.926	1.00
85_Q	88_F	0.924	1.00
67_G	302_V	0.920	1.00
200_I	273_L	0.920	1.00
400_S	570_L	0.920	1.00
464_A	468_E	0.918	1.00
475_A	545_L	0.917	1.00
214_T	218_K	0.916	1.00
570_L	575_K	0.914	1.00
349_E	432_L	0.914	1.00
41_R	44_I	0.914	1.00
331_M	335_E	0.913	1.00
381_A	417_G	0.912	1.00
434_S	438_Q	0.911	1.00
131_S	346_N	0.910	1.00
502_A	507_L	0.903	1.00
255_E	259_S	0.903	1.00
134_F	138_R	0.902	1.00
493_V	499_V	0.902	1.00
189_A	288_Y	0.901	1.00
583_Q	586_A	0.901	1.00
79_N	82_L	0.900	1.00
254_Q	257_Y	0.900	1.00
51_T	107_W	0.899	1.00
474_Q	483_S	0.899	1.00
371_S	378_A	0.898	1.00
123_L	147_I	0.897	1.00
430_L	435_L	0.897	1.00
182_L	302_V	0.895	1.00
244_E	247_A	0.894	1.00
150_D	333_S	0.893	1.00
364_S	383_S	0.891	1.00
391_T	543_K	0.888	1.00
81_E	85_Q	0.888	1.00
442_V	510_F	0.886	1.00
72_D	75_I	0.885	1.00
366_E	385_S	0.883	1.00
146_R	339_E	0.876	1.00
433_A	437_S	0.876	1.00
419_T	428_K	0.875	1.00
68_V	73_Q	0.875	1.00
67_G	72_D	0.873	1.00
176_I	187_T	0.873	1.00
214_T	262_E	0.873	1.00
494_E	498_S	0.872	1.00
92_G	96_L	0.869	1.00
354_I	425_I	0.868	1.00
593_G	596_K	0.868	1.00
469_V	515_L	0.867	1.00
211_S	259_S	0.867	1.00
122_H	126_H	0.864	1.00
215_V	260_W	0.864	1.00
454_M	489_Y	0.863	1.00
179_L	187_T	0.861	1.00
422_I	520_I	0.860	1.00
410_S	522_I	0.859	1.00
234_R	407_N	0.859	1.00
391_T	546_L	0.858	1.00
483_S	489_Y	0.857	1.00
575_K	578_E	0.854	1.00
589_G	592_A	0.853	1.00
393_A	567_I	0.850	1.00
373_D	376_R	0.850	1.00
410_S	439_I	0.850	1.00
571_D	574_R	0.848	1.00
41_R	45_L	0.848	1.00
415_A	428_K	0.847	1.00
557_R	560_T	0.847	1.00
246_M	250_D	0.845	1.00
133_R	346_N	0.845	1.00
363_I	422_I	0.845	1.00
521_I	546_L	0.845	1.00
510_F	523_L	0.844	1.00
388_A	423_D	0.841	1.00
371_S	374_E	0.841	1.00
252_V	255_E	0.838	1.00
358_K	423_D	0.836	1.00
478_A	484_D	0.835	1.00
247_A	250_D	0.835	1.00
415_A	420_I	0.835	1.00
292_L	295_N	0.834	1.00
248_Y	251_G	0.832	1.00
527_T	538_I	0.831	1.00
133_R	137_Q	0.829	1.00
198_F	202_T	0.829	1.00
64_I	67_G	0.829	1.00
475_A	479_D	0.827	1.00
243_E	246_M	0.825	1.00
293_I	298_I	0.824	1.00
476_V	507_L	0.823	1.00
356_N	430_L	0.823	1.00
356_N	359_I	0.823	1.00
371_S	375_K	0.823	1.00
535_E	539_Q	0.822	1.00
210_R	214_T	0.821	1.00
207_K	211_S	0.816	1.00
421_K	424_G	0.815	1.00
185_E	292_L	0.813	1.00
448_I	505_R	0.811	1.00
181_T	184_P	0.810	1.00
448_I	508_I	0.809	1.00
427_I	435_L	0.807	1.00
178_I	182_L	0.803	1.00
40_Y	43_T	0.802	1.00
259_S	262_E	0.800	1.00
457_I	508_I	0.799	1.00
354_I	429_D	0.798	1.00
72_D	76_T	0.795	1.00
382_V	575_K	0.794	1.00
130_L	343_E	0.794	1.00
99_A	103_L	0.792	1.00
58_V	100_A	0.791	1.00
222_L	256_N	0.790	1.00
588_G	593_G	0.788	1.00
235_V	239_F	0.788	1.00
473_S	476_V	0.787	1.00
449_F	456_N	0.786	1.00
369_E	416_A	0.783	1.00
52_V	167_T	0.783	1.00
445_D	505_R	0.783	1.00
452_T	455_E	0.782	1.00
178_I	181_T	0.779	1.00
202_T	206_K	0.777	1.00
58_V	96_L	0.777	1.00
68_V	86_L	0.774	1.00
64_I	178_I	0.772	1.00
58_V	93_L	0.771	1.00
293_I	303_F	0.771	1.00
493_V	497_G	0.770	1.00
439_I	520_I	0.769	1.00
261_R	265_R	0.769	1.00
437_S	516_A	0.768	1.00
457_I	489_Y	0.768	1.00
518_P	549_R	0.767	1.00
344_Q	348_K	0.766	1.00
478_A	508_I	0.762	1.00
43_T	110_Q	0.762	1.00
142_S	146_R	0.761	1.00
123_L	337_I	0.761	1.00
48_S	111_L	0.761	1.00
337_I	341_L	0.760	1.00
232_G	235_V	0.760	1.00
458_R	462_P	0.758	1.00
233_I	237_Q	0.757	1.00
65_L	93_L	0.757	1.00
45_L	50_L	0.757	1.00
521_I	551_A	0.757	1.00
65_L	89_I	0.757	1.00
153_S	329_M	0.756	1.00
143_I	340_F	0.756	1.00
126_H	344_Q	0.756	1.00
485_L	500_L	0.756	1.00
180_F	191_M	0.755	1.00
157_L	330_G	0.755	1.00
358_K	519_A	0.751	1.00
86_L	89_I	0.750	1.00
301_G	305_S	0.750	1.00
585_L	592_A	0.749	1.00
371_S	376_R	0.749	1.00
363_I	520_I	0.749	1.00
73_Q	76_T	0.749	1.00
255_E	258_E	0.749	1.00
361_G	550_T	0.748	1.00
68_V	72_D	0.745	1.00
430_L	434_S	0.745	1.00
40_Y	114_H	0.744	1.00
356_N	434_S	0.744	1.00
458_R	463_N	0.742	1.00
185_E	188_I	0.741	1.00
34_L	37_V	0.739	1.00
192_V	195_P	0.738	1.00
258_E	262_E	0.738	1.00
481_F	484_D	0.738	1.00
71_L	304_V	0.737	1.00
477_G	480_E	0.736	1.00
168_D	319_R	0.735	1.00
169_L	173_A	0.735	1.00
174_G	177_I	0.734	1.00
87_I	91_S	0.733	1.00
395_V	569_V	0.732	1.00
214_T	217_L	0.732	1.00
507_L	534_T	0.728	1.00
218_K	252_V	0.728	1.00
102_V	106_R	0.726	1.00
34_L	38_K	0.725	1.00
380_H	572_H	0.724	1.00
157_L	327_L	0.722	1.00
398_T	525_E	0.721	1.00
461_R	516_A	0.721	1.00
127_V	135_F	0.721	1.00
461_R	517_D	0.721	1.00
183_S	298_I	0.719	1.00
506_Q	529_S	0.719	1.00
57_A	61_V	0.719	1.00
89_I	92_G	0.718	1.00
122_H	125_T	0.718	1.00
182_L	305_S	0.717	1.00
581_H	595_V	0.715	1.00
88_F	91_S	0.715	1.00
355_H	434_S	0.713	1.00
502_A	529_S	0.710	1.00
450_S	494_E	0.708	1.00
347_V	414_D	0.708	1.00
458_R	461_R	0.707	1.00
276_M	280_I	0.707	1.00
335_E	339_E	0.706	1.00
376_R	380_H	0.705	1.00
206_K	210_R	0.704	1.00
421_K	426_P	0.703	1.00
187_T	306_F	0.701	1.00
527_T	535_E	0.699	1.00
415_A	419_T	0.699	1.00
292_L	296_E	0.698	1.00
131_S	347_V	0.698	1.00
372_Y	404_T	0.697	1.00
389_G	548_G	0.696	1.00
175_V	312_M	0.695	1.00
389_G	550_T	0.695	1.00
587_K	590_I	0.695	1.00
122_H	341_L	0.695	1.00
116_I	155_Q	0.694	1.00
183_S	187_T	0.691	1.00
407_N	413_Y	0.690	1.00
453_I	482_I	0.688	1.00
123_L	341_L	0.688	1.00
486_A	491_T	0.687	1.00
289_G	293_I	0.687	1.00
146_R	150_D	0.687	1.00
54_I	96_L	0.685	1.00
475_A	541_A	0.685	1.00
125_T	246_M	0.684	1.00
538_I	541_A	0.683	1.00
96_L	100_A	0.681	1.00
566_R	580_N	0.681	1.00
50_L	54_I	0.681	1.00
139_S	224_S	0.680	1.00
56_T	170_L	0.678	1.00
391_T	563_D	0.676	1.00
435_L	439_I	0.675	1.00
577_E	590_I	0.675	1.00
32_R	35_S	0.674	1.00
582_D	585_L	0.674	1.00
472_A	511_A	0.674	1.00
392_L	578_E	0.673	1.00
353_A	434_S	0.673	1.00
406_A	552_V	0.670	1.00
451_G	492_E	0.669	1.00
64_I	182_L	0.668	1.00
355_H	431_S	0.668	1.00
130_L	345_P	0.667	1.00
386_I	390_S	0.666	1.00
177_I	180_F	0.666	1.00
55_G	101_N	0.662	1.00
175_V	313_F	0.662	1.00
199_F	202_T	0.662	1.00
352_N	356_N	0.659	1.00
47_L	107_W	0.657	1.00
211_S	214_T	0.656	1.00
468_E	472_A	0.655	1.00
52_V	104_R	0.654	1.00
408_L	413_Y	0.654	1.00
150_D	216_R	0.653	1.00
186_L	292_L	0.653	1.00
82_L	85_Q	0.652	1.00
566_R	583_Q	0.652	1.00
466_D	489_Y	0.648	1.00
360_N	550_T	0.648	1.00
510_F	514_L	0.646	1.00
165_L	169_L	0.645	1.00
541_A	544_T	0.645	1.00
216_R	219_Q	0.645	1.00
132_H	136_D	0.644	1.00
116_I	120_R	0.644	1.00
73_Q	82_L	0.644	1.00
330_G	333_S	0.642	1.00
123_L	151_I	0.642	1.00
119_L	151_I	0.641	1.00
471_K	545_L	0.641	1.00
561_I	564_A	0.640	1.00
315_E	319_R	0.639	1.00
220_S	336_R	0.639	1.00
379_L	570_L	0.639	1.00
577_E	584_L	0.639	1.00
288_Y	291_T	0.637	1.00
374_E	416_A	0.637	1.00
154_L	334_S	0.637	1.00
84_I	87_I	0.636	1.00
65_L	68_V	0.636	1.00
535_E	560_T	0.636	1.00
539_Q	560_T	0.636	1.00
145_V	223_N	0.636	1.00
353_A	431_S	0.633	1.00
501_S	504_Q	0.632	1.00
510_F	538_I	0.631	1.00
478_A	489_Y	0.630	1.00
522_I	552_V	0.629	1.00
262_E	266_K	0.627	1.00
530_I	534_T	0.627	1.00
275_E	318_S	0.627	1.00
60_L	63_P	0.626	1.00
109_N	160_S	0.626	1.00
114_H	117_Y	0.626	1.00
466_D	473_S	0.625	1.00
394_L	552_V	0.625	1.00
359_I	438_Q	0.623	1.00
42_K	47_L	0.623	1.00
577_E	585_L	0.622	1.00
264_T	268_A	0.622	1.00
175_V	309_Y	0.620	1.00
450_S	499_V	0.620	1.00
520_I	550_T	0.619	1.00
365_F	382_V	0.619	1.00
126_H	343_E	0.618	1.00
532_T	535_E	0.618	1.00
280_I	284_V	0.617	1.00
43_T	114_H	0.616	1.00
289_G	292_L	0.616	1.00
458_R	473_S	0.616	1.00
212_W	263_A	0.616	1.00
577_E	593_G	0.616	1.00
422_I	427_I	0.615	1.00
354_I	357_E	0.614	1.00
539_Q	555_A	0.613	1.00
470_M	482_I	0.613	1.00
507_L	530_I	0.612	1.00
368_V	418_G	0.611	1.00
156_E	326_Q	0.611	1.00
452_T	490_A	0.611	1.00
204_L	270_F	0.610	1.00
183_S	186_L	0.608	1.00
370_F	378_A	0.607	1.00
581_H	584_L	0.606	1.00
406_A	441_I	0.605	1.00
384_F	575_K	0.605	1.00
477_G	538_I	0.604	1.00
203_S	206_K	0.604	1.00
590_I	594_L	0.603	1.00
445_D	496_R	0.602	1.00
382_V	570_L	0.602	1.00
117_Y	253_N	0.600	1.00
476_V	514_L	0.600	1.00
539_Q	563_D	0.600	1.00
531_D	534_T	0.600	1.00
185_E	288_Y	0.599	1.00
258_E	261_R	0.599	1.00
448_I	493_V	0.598	1.00
216_R	332_A	0.598	1.00
488_G	491_T	0.598	1.00
131_S	134_F	0.597	1.00
578_E	583_Q	0.597	1.00
376_R	572_H	0.597	1.00
442_V	523_L	0.595	1.00
415_A	426_P	0.593	1.00
31_W	34_L	0.593	1.00
142_S	336_R	0.593	1.00
474_Q	480_E	0.592	1.00
172_L	176_I	0.591	1.00
476_V	510_F	0.591	1.00
145_V	219_Q	0.590	1.00
440_S	516_A	0.590	1.00
298_I	302_V	0.590	1.00
190_I	310_L	0.589	1.00
214_T	255_E	0.589	1.00
95_V	99_A	0.589	1.00
587_K	592_A	0.588	1.00
235_V	238_A	0.588	1.00
39_P	42_K	0.587	1.00
198_F	201_S	0.587	1.00
211_S	263_A	0.586	1.00
333_S	336_R	0.585	1.00
218_K	256_N	0.585	1.00
181_T	185_E	0.584	1.00
461_R	515_L	0.584	1.00
482_I	485_L	0.583	1.00
535_E	559_S	0.583	1.00
217_L	221_K	0.583	1.00
469_V	473_S	0.583	1.00
386_I	391_T	0.582	1.00
576_I	588_G	0.582	1.00
145_V	220_S	0.579	1.00
164_N	319_R	0.578	1.00
167_T	171_L	0.577	1.00
371_S	417_G	0.576	1.00
540_Q	543_K	0.574	1.00
387_P	392_L	0.574	1.00
444_Q	502_A	0.573	1.00
368_V	383_S	0.573	1.00
443_L	446_T	0.571	1.00
109_N	113_Q	0.571	1.00
368_V	420_I	0.570	1.00
134_F	143_I	0.570	1.00
473_S	511_A	0.570	1.00
55_G	100_A	0.570	1.00
432_L	435_L	0.569	1.00
124_F	128_Q	0.569	1.00
382_V	568_I	0.568	1.00
195_P	199_F	0.568	1.00
225_H	245_N	0.568	1.00
61_V	93_L	0.568	1.00
54_I	58_V	0.567	1.00
113_Q	116_I	0.565	1.00
215_V	263_A	0.565	1.00
151_I	337_I	0.565	1.00
156_E	160_S	0.565	1.00
375_K	378_A	0.564	1.00
562_R	581_H	0.563	1.00
369_E	379_L	0.563	1.00
567_I	580_N	0.562	1.00
112_G	159_T	0.562	1.00
56_T	59_K	0.561	1.00
572_H	576_I	0.561	1.00
152_N	155_Q	0.560	1.00
98_Y	102_V	0.560	1.00
458_R	515_L	0.559	1.00
67_G	301_G	0.559	1.00
569_V	577_E	0.556	1.00
225_H	229_S	0.556	1.00
453_I	493_V	0.555	1.00
291_T	294_M	0.555	1.00
106_R	110_Q	0.553	1.00
398_T	555_A	0.553	1.00
290_A	293_I	0.552	1.00
422_I	430_L	0.551	1.00
503_G	531_D	0.551	1.00
119_L	154_L	0.551	1.00
353_A	356_N	0.550	1.00
395_V	561_I	0.550	1.00
585_L	596_K	0.550	1.00
40_Y	115_V	0.549	1.00
35_S	122_H	0.549	1.00
137_Q	373_D	0.548	1.00
407_N	441_I	0.547	1.00
251_G	254_Q	0.547	1.00
168_D	172_L	0.547	1.00
294_M	297_T	0.546	1.00
380_H	383_S	0.544	1.00
456_N	508_I	0.544	1.00
403_T	406_A	0.543	1.00
385_S	578_E	0.542	1.00
132_H	412_F	0.542	1.00
374_E	377_K	0.541	1.00
140_A	144_L	0.541	1.00
377_K	381_A	0.541	1.00
354_I	358_K	0.540	1.00
64_I	305_S	0.540	1.00
423_D	519_A	0.540	1.00
425_I	434_S	0.539	1.00
514_L	541_A	0.538	1.00
279_A	283_A	0.538	1.00
352_N	431_S	0.537	1.00
89_I	93_L	0.537	1.00
527_T	530_I	0.536	1.00
141_G	224_S	0.536	1.00
398_T	530_I	0.535	1.00
359_I	388_A	0.535	1.00
514_L	545_L	0.535	1.00
394_L	554_I	0.534	1.00
103_L	107_W	0.534	1.00
200_I	277_T	0.533	1.00
80_S	84_I	0.532	1.00
221_K	224_S	0.531	1.00
387_P	550_T	0.530	1.00
474_Q	489_Y	0.530	1.00
526_A	553_M	0.529	1.00
361_G	519_A	0.528	1.00
145_V	149_N	0.528	1.00
539_Q	553_M	0.528	1.00
268_A	272_P	0.527	1.00
91_S	95_V	0.526	1.00
482_I	486_A	0.526	1.00
62_I	66_I	0.526	1.00
256_N	260_W	0.525	1.00
394_L	570_L	0.525	1.00
39_P	122_H	0.524	1.00
404_T	413_Y	0.523	1.00
146_R	336_R	0.522	1.00
523_L	526_A	0.522	1.00
553_M	561_I	0.521	1.00
135_F	138_R	0.521	1.00
49_F	52_V	0.521	1.00
59_K	97_N	0.520	1.00
43_T	107_W	0.520	1.00
190_I	313_F	0.520	1.00
352_N	429_D	0.519	1.00
552_V	568_I	0.519	1.00
71_L	74_A	0.519	1.00
350_K	354_I	0.518	1.00
541_A	545_L	0.518	1.00
365_F	408_L	0.518	1.00
116_I	151_I	0.516	1.00
59_K	63_P	0.515	1.00
534_T	537_K	0.515	1.00
453_I	478_A	0.515	1.00
219_Q	223_N	0.514	1.00
520_I	552_V	0.514	1.00
442_V	526_A	0.514	1.00
128_Q	131_S	0.513	1.00
347_V	411_R	0.513	1.00
507_L	529_S	0.512	1.00
285_L	310_L	0.512	1.00
546_L	549_R	0.512	1.00
52_V	56_T	0.511	1.00
532_T	559_S	0.511	1.00
35_S	41_R	0.511	1.00
479_D	482_I	0.511	1.00
196_I	199_F	0.510	1.00
352_N	434_S	0.510	1.00
585_L	588_G	0.510	1.00
349_E	353_A	0.508	1.00
147_I	151_I	0.506	1.00
149_N	152_N	0.506	1.00
461_R	465_S	0.506	1.00
236_T	242_E	0.506	1.00
106_R	109_N	0.506	1.00
562_R	595_V	0.505	1.00
184_P	187_T	0.504	1.00
56_T	60_L	0.504	1.00
283_A	287_W	0.504	1.00
534_T	538_I	0.504	1.00
545_L	549_R	0.504	1.00
431_S	435_L	0.504	1.00
229_S	236_T	0.504	1.00
591_Y	594_L	0.504	1.00
469_V	472_A	0.504	1.00
457_I	460_G	0.503	1.00
113_Q	117_Y	0.503	1.00
196_I	200_I	0.503	1.00
395_V	558_L	0.503	1.00
578_E	587_K	0.503	1.00
154_L	337_I	0.502	1.00
61_V	64_I	0.502	1.00
351_P	354_I	0.502	1.00
178_I	309_Y	0.502	1.00
571_D	593_G	0.502	1.00
426_P	430_L	0.501	1.00
209_R	335_E	0.501	1.00
75_I	78_R	0.500	1.00
385_S	388_A	0.500	1.00
215_V	219_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9685	100	0.108	Contact Map
4a82A	2	0.9437	100	0.137	Contact Map
4q4hB	1	0.9652	100	0.163	Contact Map
4f4cA	1	0.9487	100	0.175	Contact Map
3b60A	2	0.9437	100	0.176	Contact Map
3b5xA	2	0.9437	100	0.177	Contact Map
4q9hA	1	0.9503	100	0.181	Contact Map
4mrsA	2	0.9685	100	0.186	Contact Map
4q4hA	1	0.9454	100	0.186	Contact Map
3zdqA	2	0.9272	100	0.187	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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