YKNU - BACSU - GREMLIN Contacts

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YKNU - Uncharacterized ABC transporter ATP-binding protein YknU

UniProt:	O31707	Sequences: METFKRLKMYYWPYRKVFMWSLLAMLLMTAITVVYPIILQITIDEIVLGRQYQLAAWVSLGFIAVMVLKGMATFFHQYLGDMFGIKSVYRLRNGLYEKLQRLSFSYYDNAKTGDLMSRLTADVEGLRFFLSYGLAELIRFGLLVAISLSVMFYYSVPLTLVTIAVLPFLAVAVYRFDKRVHPAFRGIRKSFAKLNTKVQENISGINTVKSLSREDFQISTFNKANAEYRAQYLQTSSIWSAYFPLMEFIGNTCIVALLSYGGYLVMQNQLNPGELVAFFSLVNYMMWPIMNLGFVINMFSQAKASGERLLDILEKEEDITDHPHALHKQKLTGDVHFKNVSLAYGKEQTNALCNVSFEANSGKVIGLLGPTGSGKSSVTQLLTRFYSPVGGMITIDHKPITDYSLKTLRSNIGVVLQESFLFSSTIRSNISYGRPDASMEDVIEAAKRAQAHNFIMELPDGYDTMLGERGMGLSGGQKQRIAIARAICLNPSILILDDATSAVDMQTEHSIQLALKEVMKNRTTFIVAHRISSLKHADEILVFNKGRIRERGTHHELLEKGGYYKKIYDLQYRDVKMINEPHEVG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	585 (560)
Sequences:	52556 (37399)
Seq/√Len:	1580.4

ECOLI - MDLA MSBA MDLB CYDC CYDD YOJI YDDA
BACSU - YKNU YGAD YHEH YFIC BMRA YHEI CYDD YWJA YKNV SUNT YFIB CYDC YVRA OPUAA OPUCA
HALSA - Q9HSQ7 Q9HMX3 Q9HMW0 BTUDA
SULSO - Q97UJ9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
452_H	462_Y	4.539	1.00
363_K	539_E	4.398	1.00
339_N	354_N	4.370	1.00
336_H	358_E	4.370	1.00
360_N	363_K	4.333	1.00
424_S	428_S	4.025	1.00
539_E	551_R	3.971	1.00
338_K	392_M	3.915	1.00
427_R	439_M	3.847	1.00
554_H	564_Y	3.823	1.00
447_K	452_H	3.783	1.00
338_K	394_T	3.446	1.00
334_D	358_E	3.403	1.00
452_H	456_M	3.396	1.00
392_M	399_P	3.349	1.00
353_C	547_R	3.096	1.00
337_F	340_V	3.081	1.00
427_R	463_D	3.045	1.00
427_R	431_S	3.004	1.00
561_G	565_K	2.988	1.00
439_M	443_I	2.868	1.00
379_T	527_V	2.861	1.00
446_A	462_Y	2.860	1.00
438_S	441_D	2.857	1.00
350_N	353_C	2.807	1.00
341_S	354_N	2.782	1.00
379_T	495_I	2.750	1.00
411_N	492_S	2.647	1.00
336_H	394_T	2.535	1.00
550_E	560_K	2.526	1.00
444_E	448_R	2.511	1.00
430_I	446_A	2.478	1.00
334_D	360_N	2.439	1.00
443_I	452_H	2.410	1.00
359_A	365_I	2.390	1.00
384_R	387_S	2.374	1.00
490_N	522_R	2.359	1.00
343_A	350_N	2.357	1.00
413_G	491_P	2.352	1.00
541_L	551_R	2.343	1.00
149_S	153_Y	2.333	1.00
553_T	556_E	2.326	1.00
44_D	273_G	2.305	1.00
434_R	441_D	2.303	1.00
404_S	407_T	2.277	1.00
427_R	442_V	2.265	1.00
550_E	562_G	2.248	1.00
341_S	350_N	2.234	1.00
341_S	390_G	2.196	1.00
550_E	561_G	2.193	1.00
364_V	537_A	2.175	1.00
357_F	541_L	2.155	1.00
443_I	447_K	2.143	1.00
334_D	361_S	2.132	1.00
460_D	464_T	2.092	1.00
451_A	454_F	2.085	1.00
430_I	442_V	2.071	1.00
337_F	357_F	2.047	1.00
44_D	271_N	2.037	1.00
544_N	563_Y	2.007	1.00
516_K	536_H	2.000	1.00
10_Y	94_G	1.994	1.00
508_E	530_R	1.977	1.00
359_A	525_F	1.973	1.00
441_D	490_N	1.938	1.00
333_G	396_D	1.937	1.00
387_S	401_T	1.936	1.00
339_N	356_S	1.928	1.00
14_Y	90_R	1.913	1.00
310_L	314_E	1.905	1.00
343_A	389_V	1.898	1.00
443_I	456_M	1.881	1.00
552_G	556_E	1.848	1.00
190_S	227_E	1.829	1.00
56_A	60_L	1.824	1.00
365_I	539_E	1.804	1.00
155_S	264_L	1.800	1.00
431_S	442_V	1.789	1.00
12_W	15_R	1.781	1.00
445_A	449_A	1.763	1.00
444_E	447_K	1.740	1.00
378_V	543_F	1.735	1.00
431_S	439_M	1.733	1.00
365_I	541_L	1.729	1.00
503_V	511_I	1.685	1.00
549_R	563_Y	1.685	1.00
98_K	317_E	1.676	1.00
541_L	548_I	1.674	1.00
450_Q	510_S	1.658	1.00
366_G	537_A	1.656	1.00
439_M	463_D	1.655	1.00
122_D	308_R	1.653	1.00
363_K	538_D	1.646	1.00
544_N	549_R	1.645	1.00
335_V	525_F	1.642	1.00
332_T	396_D	1.622	1.00
213_R	216_F	1.621	1.00
60_L	64_A	1.616	1.00
430_I	488_C	1.611	1.00
364_V	526_I	1.609	1.00
448_R	517_E	1.607	1.00
509_H	513_L	1.606	1.00
467_G	472_G	1.595	1.00
399_P	402_D	1.594	1.00
446_A	455_I	1.577	1.00
185_R	307_E	1.565	1.00
558_L	568_Y	1.554	1.00
453_N	456_M	1.541	1.00
367_L	541_L	1.540	1.00
367_L	378_V	1.539	1.00
263_Y	267_Q	1.533	1.00
466_L	473_L	1.532	1.00
563_Y	566_K	1.530	1.00
443_I	462_Y	1.523	1.00
334_D	396_D	1.516	1.00
556_E	560_K	1.514	1.00
437_A	488_C	1.501	1.00
352_L	355_V	1.497	1.00
441_D	444_E	1.491	1.00
528_A	533_S	1.471	1.00
321_D	404_S	1.467	1.00
535_K	555_H	1.465	1.00
550_E	565_K	1.463	1.00
40_Q	277_A	1.458	1.00
440_E	443_I	1.449	1.00
360_N	539_E	1.444	1.00
446_A	452_H	1.433	1.00
259_S	263_Y	1.427	1.00
193_K	227_E	1.426	1.00
57_W	61_G	1.422	1.00
342_L	377_S	1.421	1.00
152_F	159_T	1.419	1.00
383_T	414_V	1.413	1.00
98_K	102_L	1.409	1.00
381_L	393_I	1.408	1.00
354_N	547_R	1.383	1.00
197_K	224_A	1.381	1.00
513_L	517_E	1.376	1.00
460_D	465_M	1.373	1.00
370_P	544_N	1.372	1.00
517_E	520_K	1.360	1.00
337_F	382_L	1.354	1.00
441_D	488_C	1.351	1.00
36_P	281_L	1.351	1.00
454_F	477_Q	1.348	1.00
342_L	381_L	1.348	1.00
101_R	317_E	1.340	1.00
439_M	442_V	1.334	1.00
331_L	396_D	1.330	1.00
340_V	388_P	1.322	1.00
423_S	465_M	1.320	1.00
555_H	559_E	1.319	1.00
342_L	386_Y	1.316	1.00
413_G	486_A	1.310	1.00
186_G	231_Q	1.307	1.00
333_G	361_S	1.297	1.00
217_Q	432_Y	1.292	1.00
152_F	156_V	1.284	1.00
366_G	534_L	1.282	1.00
431_S	437_A	1.264	1.00
179_R	182_P	1.257	1.00
338_K	356_S	1.255	1.00
190_S	231_Q	1.252	1.00
467_G	470_G	1.252	1.00
24_A	72_A	1.250	1.00
370_P	563_Y	1.248	1.00
426_I	481_I	1.248	1.00
458_L	464_T	1.246	1.00
190_S	193_K	1.246	1.00
98_K	313_L	1.245	1.00
371_T	507_T	1.221	1.00
454_F	458_L	1.216	1.00
448_R	487_I	1.208	1.00
341_S	353_C	1.205	1.00
382_L	525_F	1.204	1.00
171_V	175_R	1.200	1.00
519_M	524_T	1.196	1.00
388_P	400_I	1.192	1.00
158_L	278_F	1.191	1.00
446_A	451_A	1.191	1.00
479_Q	501_S	1.190	1.00
457_E	477_Q	1.189	1.00
13_P	90_R	1.188	1.00
334_D	397_H	1.187	1.00
440_E	444_E	1.187	1.00
33_V	146_I	1.187	1.00
365_I	525_F	1.186	1.00
540_I	554_H	1.182	1.00
398_K	402_D	1.180	1.00
264_L	269_Q	1.177	1.00
434_R	437_A	1.177	1.00
151_M	278_F	1.176	1.00
451_A	455_I	1.171	1.00
201_N	217_Q	1.169	1.00
361_S	492_S	1.161	1.00
209_K	214_E	1.160	1.00
357_F	378_V	1.160	1.00
271_N	274_E	1.158	1.00
108_D	386_Y	1.143	1.00
405_L	409_R	1.143	1.00
355_V	378_V	1.142	1.00
219_S	223_K	1.142	1.00
445_A	487_I	1.142	1.00
443_I	446_A	1.141	1.00
93_N	97_E	1.138	1.00
226_A	230_A	1.138	1.00
473_L	481_I	1.131	1.00
215_D	219_S	1.118	1.00
204_G	420_F	1.115	1.00
450_Q	507_T	1.112	1.00
332_T	361_S	1.111	1.00
456_M	461_G	1.107	1.00
53_Q	57_W	1.106	1.00
398_K	403_Y	1.102	1.00
40_Q	44_D	1.097	1.00
114_D	192_A	1.094	1.00
359_A	523_T	1.094	1.00
95_L	312_I	1.093	1.00
554_H	558_L	1.084	1.00
337_F	393_I	1.083	1.00
322_H	402_D	1.081	1.00
110_A	114_D	1.078	1.00
339_N	390_G	1.077	1.00
350_N	389_V	1.070	1.00
193_K	224_A	1.064	1.00
364_V	524_T	1.063	1.00
260_Y	264_L	1.063	1.00
306_G	310_L	1.062	1.00
415_V	486_A	1.061	1.00
27_L	72_A	1.059	1.00
97_E	101_R	1.059	1.00
111_K	114_D	1.056	1.00
438_S	488_C	1.056	1.00
37_I	41_I	1.048	1.00
17_V	82_M	1.048	1.00
82_M	86_K	1.048	1.00
183_A	234_Q	1.047	1.00
261_G	275_L	1.045	1.00
337_F	378_V	1.043	1.00
165_V	253_C	1.042	1.00
453_N	457_E	1.042	1.00
564_Y	567_I	1.039	1.00
528_A	534_L	1.034	1.00
486_A	494_L	1.032	1.00
321_D	405_L	1.032	1.00
157_P	269_Q	1.031	1.00
217_Q	220_T	1.031	1.00
449_A	484_A	1.028	1.00
98_K	101_R	1.027	1.00
335_V	382_L	1.024	1.00
407_T	410_S	1.023	1.00
498_D	529_H	1.014	1.00
223_K	227_E	1.014	1.00
90_R	94_G	1.010	1.00
419_S	482_A	1.010	1.00
393_I	400_I	1.006	1.00
344_Y	351_A	1.005	1.00
526_I	537_A	1.004	1.00
563_Y	567_I	1.003	1.00
395_I	408_L	1.000	1.00
450_Q	513_L	1.000	1.00
492_S	522_R	0.999	1.00
221_F	225_N	0.998	1.00
234_Q	237_S	0.998	1.00
24_A	75_F	0.997	1.00
229_R	233_L	0.994	1.00
38_I	58_V	0.994	1.00
428_S	431_S	0.992	1.00
381_L	388_P	0.989	1.00
450_Q	514_A	0.988	1.00
371_T	480_R	0.988	1.00
197_K	220_T	0.986	1.00
108_D	380_Q	0.986	1.00
363_K	551_R	0.984	1.00
542_V	563_Y	0.981	1.00
40_Q	274_E	0.978	1.00
450_Q	517_E	0.978	1.00
494_L	522_R	0.977	1.00
160_L	164_A	0.976	1.00
19_M	23_L	0.974	1.00
125_G	305_S	0.972	1.00
510_S	513_L	0.969	1.00
455_I	462_Y	0.969	1.00
262_G	266_M	0.968	1.00
156_V	160_L	0.965	1.00
475_G	480_R	0.964	1.00
145_A	149_S	0.963	1.00
444_E	490_N	0.963	1.00
562_G	565_K	0.961	1.00
208_V	217_Q	0.959	1.00
350_N	390_G	0.958	1.00
445_A	488_C	0.956	1.00
21_S	80_G	0.955	1.00
340_V	381_L	0.954	1.00
336_H	397_H	0.952	1.00
175_R	179_R	0.952	1.00
216_F	220_T	0.950	1.00
366_G	528_A	0.948	1.00
460_D	463_D	0.941	1.00
442_V	462_Y	0.941	1.00
466_L	472_G	0.940	1.00
9_M	12_W	0.939	1.00
213_R	217_Q	0.938	1.00
220_T	224_A	0.936	1.00
376_S	380_Q	0.936	1.00
543_F	548_I	0.933	1.00
343_A	351_A	0.924	1.00
185_R	189_K	0.922	1.00
427_R	443_I	0.919	1.00
154_Y	274_E	0.917	1.00
373_S	543_F	0.917	1.00
336_H	356_S	0.913	1.00
403_Y	408_L	0.911	1.00
448_R	518_V	0.910	1.00
384_R	405_L	0.910	1.00
483_I	496_L	0.907	1.00
506_Q	510_S	0.906	1.00
24_A	79_L	0.906	1.00
354_N	390_G	0.906	1.00
103_S	318_D	0.904	1.00
41_I	45_E	0.902	1.00
335_V	395_I	0.902	1.00
395_I	493_I	0.902	1.00
179_R	238_I	0.901	1.00
303_K	307_E	0.900	1.00
459_P	464_T	0.900	1.00
161_V	260_Y	0.897	1.00
427_R	462_Y	0.897	1.00
186_G	190_S	0.897	1.00
222_N	226_A	0.896	1.00
561_G	566_K	0.896	1.00
172_A	245_L	0.896	1.00
437_A	441_D	0.896	1.00
106_Y	110_A	0.896	1.00
89_Y	93_N	0.895	1.00
447_K	456_M	0.894	1.00
94_G	98_K	0.893	1.00
556_E	559_E	0.888	1.00
366_G	540_I	0.888	1.00
415_V	483_I	0.887	1.00
467_G	471_M	0.886	1.00
64_A	68_L	0.884	1.00
407_T	411_N	0.883	1.00
183_A	231_Q	0.883	1.00
442_V	488_C	0.882	1.00
530_R	533_S	0.881	1.00
186_G	234_Q	0.880	1.00
57_W	60_L	0.880	1.00
122_D	305_S	0.878	1.00
95_L	119_L	0.877	1.00
227_E	231_Q	0.875	1.00
226_A	229_R	0.875	1.00
364_V	516_K	0.874	1.00
118_R	311_D	0.872	1.00
383_T	495_I	0.870	1.00
15_R	19_M	0.866	1.00
265_V	270_L	0.866	1.00
500_T	511_I	0.864	1.00
14_Y	86_K	0.861	1.00
383_T	412_I	0.861	1.00
216_F	219_S	0.861	1.00
388_P	401_T	0.857	1.00
364_V	519_M	0.856	1.00
392_M	401_T	0.855	1.00
548_I	551_R	0.854	1.00
264_L	267_Q	0.851	1.00
148_L	159_T	0.850	1.00
343_A	346_K	0.849	1.00
330_K	396_D	0.849	1.00
456_M	462_Y	0.848	1.00
388_P	393_I	0.847	1.00
494_L	519_M	0.847	1.00
322_H	325_A	0.846	1.00
448_R	452_H	0.844	1.00
421_L	478_K	0.840	1.00
206_N	380_Q	0.837	1.00
218_I	222_N	0.837	1.00
187_I	232_Y	0.837	1.00
430_I	481_I	0.836	1.00
491_P	522_R	0.836	1.00
361_S	396_D	0.835	1.00
451_A	457_E	0.834	1.00
466_L	470_G	0.834	1.00
179_R	183_A	0.834	1.00
406_K	410_S	0.832	1.00
220_T	223_K	0.831	1.00
338_K	358_E	0.831	1.00
21_S	83_F	0.829	1.00
355_V	548_I	0.829	1.00
449_A	480_R	0.824	1.00
421_L	481_I	0.823	1.00
309_L	313_L	0.818	1.00
508_E	512_Q	0.817	1.00
151_M	159_T	0.816	1.00
105_S	109_N	0.814	1.00
544_N	547_R	0.813	1.00
422_F	429_N	0.812	1.00
400_I	408_L	0.811	1.00
219_S	222_N	0.810	1.00
182_P	186_G	0.809	1.00
328_K	403_Y	0.807	1.00
394_T	397_H	0.803	1.00
345_G	349_T	0.803	1.00
316_E	320_T	0.800	1.00
224_A	227_E	0.799	1.00
207_T	211_L	0.799	1.00
170_A	174_Y	0.798	1.00
343_A	347_E	0.798	1.00
328_K	331_L	0.796	1.00
54_L	57_W	0.794	1.00
215_D	218_I	0.794	1.00
12_W	16_K	0.793	1.00
174_Y	178_K	0.793	1.00
425_T	428_S	0.792	1.00
31_I	72_A	0.788	1.00
324_H	328_K	0.788	1.00
114_D	118_R	0.787	1.00
430_I	462_Y	0.786	1.00
326_L	398_K	0.786	1.00
205_I	209_K	0.782	1.00
153_Y	156_V	0.782	1.00
37_I	150_V	0.779	1.00
155_S	159_T	0.779	1.00
341_S	389_V	0.779	1.00
451_A	481_I	0.777	1.00
335_V	493_I	0.776	1.00
38_I	65_V	0.776	1.00
95_L	309_L	0.775	1.00
115_L	312_I	0.773	1.00
231_Q	234_Q	0.773	1.00
31_I	68_L	0.772	1.00
494_L	524_T	0.772	1.00
333_G	523_T	0.772	1.00
233_L	237_S	0.771	1.00
105_S	318_D	0.769	1.00
71_M	75_F	0.768	1.00
157_P	264_L	0.767	1.00
150_V	154_Y	0.767	1.00
194_L	228_Y	0.763	1.00
273_G	277_A	0.762	1.00
8_K	12_W	0.761	1.00
41_I	58_V	0.760	1.00
412_I	493_I	0.759	1.00
319_I	387_S	0.758	1.00
25_M	139_R	0.756	1.00
403_Y	407_T	0.755	1.00
16_K	20_W	0.754	1.00
410_S	489_L	0.750	1.00
41_I	44_D	0.750	1.00
44_D	47_V	0.750	1.00
558_L	565_K	0.750	1.00
431_S	436_D	0.749	1.00
418_E	478_K	0.748	1.00
37_I	40_Q	0.748	1.00
31_I	65_V	0.748	1.00
343_A	349_T	0.748	1.00
431_S	435_P	0.747	1.00
204_G	207_T	0.747	1.00
150_V	153_Y	0.745	1.00
102_L	315_K	0.743	1.00
479_Q	502_A	0.742	1.00
129_F	302_A	0.741	1.00
368_L	542_V	0.741	1.00
446_A	449_A	0.739	1.00
59_S	63_I	0.738	1.00
454_F	457_E	0.738	1.00
264_L	268_N	0.738	1.00
99_L	107_Y	0.737	1.00
230_A	234_Q	0.737	1.00
458_L	473_L	0.737	1.00
157_P	160_L	0.735	1.00
265_V	275_L	0.735	1.00
140_F	291_N	0.735	1.00
30_A	34_V	0.735	1.00
431_S	434_R	0.734	1.00
8_K	11_Y	0.732	1.00
326_L	402_D	0.731	1.00
129_F	299_F	0.730	1.00
17_V	86_K	0.730	1.00
328_K	407_T	0.730	1.00
146_I	149_S	0.728	1.00
371_T	498_D	0.725	1.00
45_E	54_L	0.725	1.00
362_G	523_T	0.724	1.00
227_E	230_A	0.724	1.00
60_L	63_I	0.724	1.00
353_C	545_K	0.722	1.00
125_G	301_Q	0.721	1.00
190_S	224_A	0.721	1.00
330_K	492_S	0.720	1.00
103_S	319_I	0.719	1.00
480_R	507_T	0.719	1.00
475_G	502_A	0.716	1.00
38_I	61_G	0.714	1.00
74_F	78_Y	0.714	1.00
164_A	167_P	0.714	1.00
58_V	61_G	0.713	1.00
564_Y	568_Y	0.712	1.00
500_T	508_E	0.712	1.00
248_F	252_T	0.711	1.00
17_V	79_L	0.711	1.00
61_G	64_A	0.711	1.00
43_I	276_V	0.711	1.00
27_L	68_L	0.709	1.00
141_G	145_A	0.709	1.00
154_Y	277_A	0.708	1.00
23_L	27_L	0.706	1.00
554_H	568_Y	0.704	1.00
327_H	407_T	0.703	1.00
186_G	189_K	0.702	1.00
155_S	270_L	0.701	1.00
434_R	490_N	0.698	1.00
178_K	182_P	0.698	1.00
362_G	521_N	0.698	1.00
29_T	142_L	0.697	1.00
159_T	278_F	0.696	1.00
94_G	97_E	0.695	1.00
68_L	72_A	0.695	1.00
388_P	392_M	0.693	1.00
147_S	284_Y	0.693	1.00
260_Y	263_Y	0.691	1.00
394_T	399_P	0.691	1.00
45_E	48_L	0.690	1.00
365_I	551_R	0.689	1.00
380_Q	386_Y	0.688	1.00
98_K	316_E	0.686	1.00
423_S	467_G	0.685	1.00
439_M	462_Y	0.684	1.00
434_R	489_L	0.683	1.00
307_E	311_D	0.683	1.00
349_T	353_C	0.682	1.00
152_F	163_I	0.681	1.00
408_L	412_I	0.680	1.00
171_V	174_Y	0.680	1.00
555_H	558_L	0.680	1.00
20_W	79_L	0.678	1.00
448_R	514_A	0.678	1.00
450_Q	453_N	0.678	1.00
441_D	445_A	0.677	1.00
325_A	328_K	0.676	1.00
147_S	285_M	0.675	1.00
511_I	514_A	0.675	1.00
94_G	313_L	0.675	1.00
97_E	218_I	0.672	1.00
426_I	455_I	0.671	1.00
359_A	363_K	0.671	1.00
37_I	154_Y	0.671	1.00
261_G	265_V	0.670	1.00
344_Y	377_S	0.670	1.00
118_R	122_D	0.669	1.00
560_K	563_Y	0.667	1.00
451_A	462_Y	0.667	1.00
188_R	191_F	0.665	1.00
44_D	48_L	0.664	1.00
88_V	92_R	0.663	1.00
554_H	557_L	0.662	1.00
539_E	553_T	0.661	1.00
95_L	313_L	0.660	1.00
137_L	141_G	0.660	1.00
508_E	533_S	0.659	1.00
149_S	152_F	0.656	1.00
352_L	543_F	0.655	1.00
395_I	400_I	0.653	1.00
379_T	525_F	0.653	1.00
550_E	557_L	0.653	1.00
155_S	158_L	0.652	1.00
439_M	446_A	0.652	1.00
327_H	404_S	0.652	1.00
88_V	127_R	0.652	1.00
54_L	58_V	0.651	1.00
512_Q	533_S	0.650	1.00
443_I	455_I	0.649	1.00
91_L	123_V	0.648	1.00
302_A	305_S	0.648	1.00
364_V	536_H	0.648	1.00
320_T	323_P	0.647	1.00
483_I	487_I	0.646	1.00
192_A	308_R	0.646	1.00
474_S	477_Q	0.645	1.00
381_L	386_Y	0.644	1.00
111_K	196_T	0.644	1.00
534_L	537_A	0.643	1.00
512_Q	528_A	0.643	1.00
28_M	73_T	0.642	1.00
332_T	523_T	0.641	1.00
117_S	195_N	0.641	1.00
421_L	466_L	0.640	1.00
67_V	71_M	0.639	1.00
104_F	108_D	0.639	1.00
561_G	564_Y	0.639	1.00
483_I	511_I	0.636	1.00
183_A	186_G	0.636	1.00
539_E	556_E	0.635	1.00
367_L	525_F	0.635	1.00
33_V	36_P	0.635	1.00
81_D	132_Y	0.633	1.00
550_E	563_Y	0.633	1.00
95_L	123_V	0.632	1.00
495_I	525_F	0.632	1.00
252_T	256_A	0.632	1.00
126_L	306_G	0.630	1.00
162_T	282_V	0.628	1.00
503_V	507_T	0.628	1.00
418_E	469_R	0.628	1.00
25_M	76_H	0.627	1.00
236_S	240_S	0.626	1.00
550_E	558_L	0.626	1.00
326_L	329_Q	0.626	1.00
423_S	472_G	0.626	1.00
287_W	291_N	0.626	1.00
9_M	94_G	0.625	1.00
122_D	188_R	0.625	1.00
424_S	465_M	0.624	1.00
325_A	407_T	0.620	1.00
98_K	315_K	0.620	1.00
431_S	446_A	0.619	1.00
247_E	290_M	0.618	1.00
379_T	414_V	0.616	1.00
234_Q	238_I	0.616	1.00
337_F	355_V	0.614	1.00
444_E	518_V	0.614	1.00
114_D	308_R	0.612	1.00
425_T	463_D	0.610	1.00
147_S	281_L	0.609	1.00
357_F	548_I	0.609	1.00
413_G	489_L	0.609	1.00
91_L	126_L	0.608	1.00
262_G	265_V	0.608	1.00
445_A	484_A	0.607	1.00
86_K	89_Y	0.607	1.00
340_V	391_G	0.606	1.00
505_M	508_E	0.606	1.00
158_L	264_L	0.604	1.00
396_D	492_S	0.604	1.00
346_K	389_V	0.603	1.00
442_V	446_A	0.601	1.00
331_L	411_N	0.601	1.00
514_A	517_E	0.600	1.00
128_F	298_M	0.600	1.00
508_E	532_S	0.600	1.00
184_F	235_T	0.600	1.00
551_R	556_E	0.599	1.00
415_V	496_L	0.598	1.00
139_R	143_L	0.598	1.00
493_I	523_T	0.597	1.00
342_L	351_A	0.597	1.00
89_Y	225_N	0.595	1.00
13_P	16_K	0.593	1.00
56_A	59_S	0.592	1.00
562_G	567_I	0.592	1.00
480_R	503_V	0.592	1.00
359_A	364_V	0.592	1.00
103_S	106_Y	0.592	1.00
504_D	507_T	0.592	1.00
102_L	317_E	0.591	1.00
346_K	349_T	0.591	1.00
560_K	565_K	0.589	1.00
512_Q	536_H	0.589	1.00
371_T	528_A	0.589	1.00
34_V	65_V	0.588	1.00
476_G	504_D	0.587	1.00
535_K	554_H	0.587	1.00
188_R	304_A	0.586	1.00
355_V	543_F	0.586	1.00
550_E	566_K	0.585	1.00
140_F	144_V	0.585	1.00
270_L	274_E	0.585	1.00
405_L	408_L	0.584	1.00
81_D	85_I	0.583	1.00
449_A	487_I	0.583	1.00
14_Y	17_V	0.583	1.00
207_T	210_S	0.582	1.00
106_Y	115_L	0.582	1.00
360_N	365_I	0.580	1.00
449_A	483_I	0.580	1.00
19_M	22_L	0.580	1.00
450_Q	511_I	0.580	1.00
347_E	350_N	0.580	1.00
347_E	351_A	0.580	1.00
47_V	50_R	0.580	1.00
343_A	390_G	0.577	1.00
175_R	178_K	0.577	1.00
123_V	309_L	0.577	1.00
349_T	545_K	0.576	1.00
186_G	227_E	0.576	1.00
176_F	242_Y	0.575	1.00
117_S	191_F	0.574	1.00
340_V	393_I	0.572	1.00
172_A	249_I	0.572	1.00
167_P	171_V	0.571	1.00
128_F	132_Y	0.571	1.00
14_Y	87_S	0.571	1.00
40_Q	273_G	0.570	1.00
124_E	127_R	0.570	1.00
461_G	464_T	0.569	1.00
333_G	492_S	0.569	1.00
319_I	384_R	0.568	1.00
305_S	308_R	0.566	1.00
447_K	453_N	0.566	1.00
542_V	550_E	0.565	1.00
434_R	488_C	0.565	1.00
157_P	260_Y	0.565	1.00
346_K	350_N	0.565	1.00
109_N	345_G	0.564	1.00
13_P	94_G	0.563	1.00
190_S	228_Y	0.563	1.00
52_Y	56_A	0.563	1.00
53_Q	56_A	0.563	1.00
540_I	553_T	0.562	1.00
230_A	233_L	0.561	1.00
117_S	192_A	0.561	1.00
96_Y	100_Q	0.561	1.00
189_K	193_K	0.560	1.00
197_K	201_N	0.560	1.00
27_L	31_I	0.559	1.00
455_I	458_L	0.559	1.00
549_R	561_G	0.558	1.00
355_V	541_L	0.558	1.00
431_S	488_C	0.557	1.00
545_K	549_R	0.557	1.00
85_I	88_V	0.556	1.00
398_K	407_T	0.556	1.00
340_V	356_S	0.555	1.00
104_F	385_F	0.554	1.00
325_A	404_S	0.554	1.00
417_Q	475_G	0.554	1.00
126_L	309_L	0.554	1.00
16_K	19_M	0.553	1.00
388_P	399_P	0.553	1.00
426_I	466_L	0.551	1.00
395_I	403_Y	0.550	1.00
416_L	419_S	0.549	1.00
447_K	462_Y	0.548	1.00
70_G	74_F	0.548	1.00
371_T	503_V	0.548	1.00
380_Q	414_V	0.548	1.00
84_G	131_S	0.547	1.00
442_V	445_A	0.546	1.00
240_S	244_P	0.546	1.00
562_G	566_K	0.545	1.00
117_S	121_A	0.545	1.00
183_A	235_T	0.545	1.00
487_I	518_V	0.544	1.00
14_Y	83_F	0.544	1.00
170_A	173_V	0.544	1.00
513_L	516_K	0.543	1.00
415_V	499_A	0.543	1.00
452_H	455_I	0.543	1.00
270_L	275_L	0.542	1.00
78_Y	82_M	0.542	1.00
156_V	159_T	0.542	1.00
487_I	514_A	0.541	1.00
187_I	235_T	0.541	1.00
37_I	277_A	0.540	1.00
350_N	354_N	0.540	1.00
446_A	484_A	0.540	1.00
136_E	291_N	0.539	1.00
144_V	148_L	0.539	1.00
322_H	404_S	0.535	1.00
29_T	33_V	0.533	1.00
61_G	65_V	0.533	1.00
46_I	54_L	0.533	1.00
197_K	217_Q	0.532	1.00
360_N	523_T	0.531	1.00
28_M	72_A	0.531	1.00
353_C	356_S	0.531	1.00
429_N	481_I	0.531	1.00
63_I	67_V	0.530	1.00
100_Q	103_S	0.528	1.00
331_L	361_S	0.528	1.00
51_Q	54_L	0.527	1.00
557_L	564_Y	0.527	1.00
430_I	433_G	0.527	1.00
368_L	534_L	0.527	1.00
324_H	402_D	0.526	1.00
261_G	264_L	0.526	1.00
263_Y	266_M	0.525	1.00
112_T	116_M	0.525	1.00
544_N	566_K	0.525	1.00
315_K	318_D	0.524	1.00
359_A	541_L	0.524	1.00
499_A	528_A	0.522	1.00
377_S	386_Y	0.522	1.00
358_E	551_R	0.521	1.00
377_S	381_L	0.521	1.00
223_K	226_A	0.520	1.00
493_I	525_F	0.520	1.00
148_L	152_F	0.520	1.00
507_T	511_I	0.518	1.00
526_I	534_L	0.518	1.00
434_R	438_S	0.517	1.00
376_S	379_T	0.517	1.00
367_L	527_V	0.517	1.00
10_Y	13_P	0.517	1.00
266_M	269_Q	0.517	1.00
316_E	319_I	0.516	1.00
341_S	352_L	0.515	1.00
326_L	330_K	0.514	1.00
499_A	526_I	0.514	1.00
367_L	543_F	0.514	1.00
519_M	522_R	0.513	1.00
118_R	308_R	0.513	1.00
208_V	214_E	0.513	1.00
35_Y	39_L	0.512	1.00
500_T	503_V	0.511	1.00
22_L	25_M	0.511	1.00
163_I	167_P	0.511	1.00
525_F	541_L	0.511	1.00
107_Y	110_A	0.510	1.00
426_I	451_A	0.510	1.00
119_L	123_V	0.510	1.00
514_A	518_V	0.510	1.00
17_V	83_F	0.509	1.00
72_A	75_F	0.509	1.00
32_T	69_K	0.509	1.00
480_R	502_A	0.508	1.00
328_K	398_K	0.507	1.00
113_G	196_T	0.507	1.00
331_L	395_I	0.507	1.00
251_N	255_V	0.506	1.00
48_L	51_Q	0.506	1.00
151_M	162_T	0.506	1.00
121_A	188_R	0.505	1.00
88_V	123_V	0.505	1.00
404_S	408_L	0.504	1.00
337_F	381_L	0.504	1.00
10_Y	91_L	0.504	1.00
512_Q	526_I	0.504	1.00
384_R	400_I	0.503	1.00
153_Y	157_P	0.503	1.00
140_F	143_L	0.503	1.00
38_I	41_I	0.502	1.00
29_T	32_T	0.501	1.00
191_F	195_N	0.501	1.00
324_H	404_S	0.501	1.00
507_T	510_S	0.501	1.00
135_A	138_I	0.501	1.00
75_F	79_L	0.500	1.00
228_Y	232_Y	0.500	1.00
542_V	549_R	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9573	100	0.092	Contact Map
4a82A	2	0.9761	100	0.12	Contact Map
4q4hB	1	0.9761	100	0.152	Contact Map
3b5xA	2	0.9761	100	0.162	Contact Map
4f4cA	1	0.959	100	0.162	Contact Map
3b60A	2	0.9761	100	0.163	Contact Map
4q4hA	1	0.9761	100	0.164	Contact Map
3zdqA	2	0.9573	100	0.172	Contact Map
4mrsA	2	0.9932	100	0.177	Contact Map
4q9hA	1	0.9778	100	0.181	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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