STOA - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

STOA - Sporulation thiol-disulfide oxidoreductase A

UniProt:	O31687	Sequences: MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLKEWTEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	165 (133)
Sequences:	11758 (8968)
Seq/√Len:	777.6

ECOLI - DSBE TPX BCP AHPC
BACSU - STOA RESA YNEN YKUV TPX BCP YKUU AHPC
HALSA - Q9HP28 Q9HQE6 Q9HRG4 Q9HN00
SULSO - Q97WP9 Q97VL0 Q97WG5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
55_K	142_E	3.938	1.00
41_T	45_E	2.970	1.00
76_Q	114_T	2.730	1.00
54_Q	88_K	2.635	1.00
101_Q	105_E	2.633	1.00
38_L	46_D	2.578	1.00
141_N	145_E	2.553	1.00
141_N	147_E	2.472	1.00
40_K	46_D	2.372	1.00
140_L	146_I	2.145	1.00
38_L	48_S	2.072	1.00
48_S	51_N	2.026	1.00
76_Q	80_D	2.018	1.00
56_T	88_K	1.996	1.00
59_H	71_E	1.880	1.00
41_T	47_I	1.876	1.00
33_V	145_E	1.816	1.00
91_T	115_F	1.787	1.00
42_I	108_I	1.751	1.00
69_K	111_N	1.748	1.00
34_P	129_Y	1.745	1.00
57_I	139_L	1.675	1.00
79_Y	83_P	1.595	1.00
81_A	160_K	1.582	1.00
36_V	50_P	1.526	1.00
29_K	32_A	1.497	1.00
100_N	103_V	1.481	1.00
59_H	137_S	1.427	1.00
77_S	156_A	1.409	1.00
105_E	109_K	1.403	1.00
74_Q	77_S	1.373	1.00
124_E	128_E	1.354	1.00
36_V	48_S	1.353	1.00
72_L	113_L	1.352	1.00
55_K	147_E	1.340	1.00
55_K	139_L	1.334	1.00
74_Q	156_A	1.307	1.00
94_L	126_M	1.296	1.00
158_Q	161_E	1.294	1.00
136_T	149_T	1.288	1.00
102_Q	106_D	1.286	1.00
93_N	104_V	1.285	1.00
39_M	118_V	1.257	1.00
156_A	160_K	1.257	1.00
69_K	110_A	1.240	1.00
101_Q	119_L	1.223	1.00
107_F	111_N	1.209	1.00
155_T	158_Q	1.207	1.00
57_I	75_F	1.197	1.00
57_I	137_S	1.178	1.00
65_C	68_C	1.165	1.00
69_K	107_F	1.150	1.00
56_T	140_L	1.133	1.00
71_E	137_S	1.131	1.00
47_I	51_N	1.123	1.00
65_C	111_N	1.121	1.00
88_K	116_P	1.118	1.00
57_I	87_V	1.117	1.00
138_F	146_I	1.104	1.00
62_T	134_I	1.099	1.00
77_S	80_D	1.095	1.00
64_W	104_V	1.087	1.00
63_S	104_V	1.079	1.00
94_L	123_G	1.069	1.00
78_F	159_L	1.046	1.00
83_P	88_K	1.036	1.00
37_F	125_L	1.036	1.00
108_I	117_I	1.034	1.00
80_D	83_P	1.018	1.00
28_E	31_P	1.006	1.00
53_G	142_E	1.004	1.00
31_P	145_E	1.004	1.00
75_F	89_L	0.998	1.00
106_D	109_K	0.996	1.00
60_F	129_Y	0.992	1.00
106_D	110_A	0.992	1.00
104_V	119_L	0.979	1.00
79_Y	114_T	0.975	1.00
83_P	86_S	0.972	1.00
77_S	81_A	0.970	1.00
131_I	136_T	0.966	1.00
58_L	140_L	0.966	1.00
70_K	153_P	0.954	1.00
40_K	101_Q	0.943	1.00
120_D	123_G	0.935	1.00
124_E	127_K	0.931	1.00
94_L	134_I	0.918	1.00
157_E	160_K	0.905	1.00
56_T	90_V	0.904	1.00
42_I	105_E	0.900	1.00
78_F	81_A	0.895	1.00
76_Q	115_F	0.884	1.00
41_T	118_V	0.882	1.00
79_Y	88_K	0.876	1.00
102_Q	105_E	0.871	1.00
63_S	107_F	0.862	1.00
59_H	67_P	0.854	1.00
139_L	150_K	0.853	1.00
78_F	82_H	0.850	1.00
36_V	49_I	0.845	1.00
66_P	70_K	0.844	1.00
76_Q	112_K	0.842	1.00
52_K	56_T	0.836	1.00
39_M	125_L	0.828	1.00
60_F	92_V	0.814	1.00
30_Q	148_K	0.814	1.00
81_A	156_A	0.803	1.00
139_L	148_K	0.799	1.00
73_P	77_S	0.797	1.00
41_T	116_P	0.777	1.00
150_K	154_M	0.772	1.00
72_L	76_Q	0.765	1.00
74_Q	153_P	0.758	1.00
86_S	142_E	0.757	1.00
72_L	111_N	0.756	1.00
123_G	127_K	0.750	1.00
61_W	117_I	0.748	1.00
60_F	131_I	0.741	1.00
49_I	56_T	0.741	1.00
28_E	32_A	0.740	1.00
43_E	105_E	0.735	1.00
140_L	144_G	0.734	1.00
82_H	87_V	0.731	1.00
64_W	134_I	0.722	1.00
82_H	85_D	0.716	1.00
126_M	131_I	0.713	1.00
108_I	113_L	0.711	1.00
70_K	73_P	0.709	1.00
146_I	149_T	0.700	1.00
55_K	87_V	0.699	1.00
74_Q	78_F	0.686	1.00
150_K	153_P	0.685	1.00
82_H	160_K	0.685	1.00
53_G	144_G	0.685	1.00
125_L	128_E	0.678	1.00
95_V	123_G	0.676	1.00
72_L	107_F	0.672	1.00
67_P	134_I	0.672	1.00
157_E	161_E	0.662	1.00
125_L	129_Y	0.652	1.00
103_V	106_D	0.646	1.00
37_F	49_I	0.645	1.00
60_F	125_L	0.644	1.00
133_T	136_T	0.637	1.00
30_Q	149_T	0.636	1.00
40_K	121_S	0.631	1.00
91_T	117_I	0.630	1.00
47_I	118_V	0.625	1.00
52_K	144_G	0.621	1.00
63_S	67_P	0.611	1.00
66_P	69_K	0.607	1.00
80_D	114_T	0.605	1.00
127_K	132_I	0.600	1.00
104_V	117_I	0.599	1.00
73_P	76_Q	0.594	1.00
93_N	96_N	0.593	1.00
67_P	153_P	0.593	1.00
76_Q	111_N	0.588	1.00
136_T	151_I	0.586	1.00
62_T	67_P	0.586	1.00
55_K	86_S	0.578	1.00
75_F	137_S	0.576	1.00
61_W	93_N	0.572	1.00
59_H	75_F	0.571	1.00
76_Q	79_Y	0.570	1.00
65_C	110_A	0.569	1.00
75_F	91_T	0.569	1.00
96_N	103_V	0.566	1.00
57_I	89_L	0.564	1.00
91_T	113_L	0.563	1.00
56_T	144_G	0.559	1.00
59_H	72_L	0.558	1.00
34_P	140_L	0.557	1.00
79_Y	82_H	0.555	1.00
113_L	117_I	0.543	1.00
156_A	159_L	0.543	1.00
33_V	52_K	0.539	1.00
82_H	86_S	0.537	1.00
62_T	65_C	0.537	1.00
138_F	149_T	0.536	1.00
63_S	103_V	0.533	1.00
65_C	103_V	0.529	1.00
49_I	52_K	0.528	1.00
108_I	112_K	0.528	1.00
67_P	73_P	0.528	1.00
96_N	100_N	0.526	1.00
123_G	126_M	0.522	1.00
154_M	157_E	0.520	1.00
104_V	107_F	0.518	1.00
72_L	115_F	0.518	1.00
70_K	74_Q	0.518	1.00
58_L	129_Y	0.517	1.00
120_D	126_M	0.516	1.00
92_V	125_L	0.515	1.00
62_T	66_P	0.511	1.00
78_F	89_L	0.507	1.00
35_A	138_F	0.506	1.00
53_G	56_T	0.505	1.00
68_C	71_E	0.500	1.00
105_E	108_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hyxA	2	0.9879	100	0.275	Contact Map
3eytA	4	0.8303	100	0.326	Contact Map
3eurA	1	0.8121	100	0.328	Contact Map
3lorA	3	0.8303	100	0.329	Contact Map
4nmuA	2	0.8667	100	0.333	Contact Map
2p5qA	3	0.8121	100	0.334	Contact Map
3erwA	1	0.8121	100	0.336	Contact Map
2f9sA	1	0.8121	100	0.337	Contact Map
2h30A	1	0.8242	100	0.337	Contact Map
4yodA	1	0.9636	100	0.34	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0068 seconds.