QUED - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

QUED - 6-carboxy-5,6,7,8-tetrahydropterin synthase

UniProt:	O31676	Sequences: MLSQIYPQAQHPYSFELNKDMHISAAHFIPRESAGACSRVHGHTYTVNITVAGDELDDSGFLVNFSVLKKLVHGNYDHTLLNDHEDFSQDDRYSLPTTEVVAKTIYDNVQAYLDTLENKPTCVQVFVRETPTSYCVYRPKKGGLNG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	146 (116)
Sequences:	2344 (1348)
Seq/√Len:	125.2

ECOLI - QUED
BACSU - QUED
HALSA - Q9HHN6 Q9HQS7
SULSO - Q97W30

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
24_S	44_T	3.325	1.00
53_G	62_L	3.001	1.00
124_Q	138_R	2.701	1.00
126_F	136_V	2.623	1.00
20_D	46_T	2.364	1.00
124_Q	136_V	2.321	1.00
48_N	126_F	2.310	1.00
20_D	48_N	2.269	1.00
16_E	52_A	2.231	1.00
28_F	80_L	2.215	1.00
103_K	107_D	2.189	1.00
75_N	108_N	2.103	1.00
18_N	50_T	2.055	1.00
76_Y	104_T	2.016	1.00
47_V	127_V	1.945	1.00
52_A	123_V	1.941	1.00
18_N	134_Y	1.730	1.00
76_Y	105_I	1.709	1.00
106_Y	137_Y	1.700	1.00
16_E	50_T	1.631	1.00
36_A	66_S	1.627	1.00
39_R	79_T	1.617	1.00
40_V	80_L	1.607	1.00
48_N	128_R	1.538	1.00
49_I	72_V	1.527	1.00
49_I	109_V	1.516	1.00
50_T	124_Q	1.505	1.00
110_Q	139_P	1.505	1.00
102_A	125_V	1.493	1.00
104_T	108_N	1.480	1.00
51_V	68_L	1.479	1.00
23_I	47_V	1.425	1.00
106_Y	139_P	1.399	1.00
51_V	63_V	1.389	1.00
100_V	103_K	1.387	1.00
18_N	126_F	1.385	1.00
103_K	137_Y	1.380	1.00
30_P	38_S	1.370	1.00
26_A	80_L	1.319	1.00
21_M	72_V	1.275	1.00
22_H	132_T	1.258	1.00
16_E	123_V	1.226	0.99
85_E	88_S	1.209	0.99
21_M	69_K	1.201	0.99
18_N	48_N	1.199	0.99
82_N	96_P	1.196	0.99
16_E	136_V	1.195	0.99
64_N	67_V	1.193	0.99
45_Y	98_T	1.190	0.99
60_G	100_V	1.157	0.99
44_T	131_P	1.139	0.99
50_T	126_F	1.103	0.99
15_F	103_K	1.087	0.99
102_A	135_C	1.050	0.98
32_E	35_G	1.048	0.98
126_F	134_Y	1.039	0.98
19_K	132_T	1.037	0.98
108_N	111_A	1.026	0.98
61_F	97_T	1.019	0.98
114_D	117_E	0.986	0.97
46_T	131_P	0.967	0.97
25_A	81_L	0.934	0.97
22_H	44_T	0.922	0.96
105_I	125_V	0.914	0.96
94_S	104_T	0.911	0.96
76_Y	101_V	0.903	0.96
38_S	97_T	0.901	0.96
66_S	69_K	0.900	0.96
22_H	46_T	0.899	0.96
37_C	129_E	0.897	0.96
17_L	134_Y	0.890	0.95
37_C	78_H	0.888	0.95
16_E	124_Q	0.880	0.95
19_K	133_S	0.878	0.95
22_H	131_P	0.875	0.95
46_T	128_R	0.869	0.95
44_T	128_R	0.850	0.94
28_F	38_S	0.828	0.93
105_I	109_V	0.826	0.93
23_I	127_V	0.826	0.93
56_L	59_S	0.825	0.93
110_Q	114_D	0.818	0.93
24_S	131_P	0.804	0.92
34_A	38_S	0.804	0.92
65_F	133_S	0.799	0.92
63_V	71_L	0.795	0.92
18_N	136_V	0.792	0.92
16_E	138_R	0.780	0.91
21_M	73_H	0.770	0.91
106_Y	125_V	0.769	0.90
67_V	70_K	0.767	0.90
127_V	135_C	0.749	0.89
63_V	67_V	0.743	0.89
47_V	72_V	0.737	0.89
116_L	122_C	0.735	0.88
19_K	130_T	0.734	0.88
27_H	99_E	0.732	0.88
25_A	45_Y	0.726	0.88
128_R	134_Y	0.725	0.88
98_T	135_C	0.722	0.87
55_E	103_K	0.721	0.87
123_V	138_R	0.715	0.87
44_T	132_T	0.715	0.87
82_N	85_E	0.713	0.87
20_D	131_P	0.711	0.87
84_H	88_S	0.710	0.87
106_Y	122_C	0.708	0.86
101_V	105_I	0.707	0.86
102_A	127_V	0.706	0.86
107_D	110_Q	0.705	0.86
68_L	113_L	0.702	0.86
103_K	106_Y	0.696	0.86
49_I	125_V	0.695	0.85
33_S	61_F	0.692	0.85
112_Y	115_T	0.687	0.85
107_D	139_P	0.684	0.85
36_A	74_G	0.683	0.84
76_Y	108_N	0.681	0.84
98_T	131_P	0.681	0.84
65_F	69_K	0.678	0.84
30_P	95_L	0.677	0.84
20_D	132_T	0.664	0.83
45_Y	127_V	0.660	0.82
26_A	40_V	0.633	0.80
29_I	130_T	0.633	0.80
15_F	56_L	0.630	0.79
69_K	73_H	0.620	0.78
15_F	55_E	0.619	0.78
105_I	127_V	0.617	0.78
28_F	40_V	0.616	0.78
15_F	137_Y	0.615	0.78
19_K	72_V	0.612	0.77
32_E	59_S	0.608	0.77
29_I	95_L	0.604	0.76
71_L	112_Y	0.604	0.76
107_D	111_A	0.596	0.76
59_S	97_T	0.595	0.75
41_H	129_E	0.594	0.75
40_V	65_F	0.593	0.75
26_A	130_T	0.591	0.75
82_N	101_V	0.590	0.75
76_Y	86_D	0.586	0.74
51_V	109_V	0.585	0.74
71_L	109_V	0.582	0.74
86_D	89_Q	0.578	0.73
98_T	101_V	0.574	0.73
34_A	59_S	0.573	0.73
106_Y	110_Q	0.571	0.72
71_L	113_L	0.570	0.72
98_T	133_S	0.564	0.72
70_K	73_H	0.563	0.71
98_T	129_E	0.563	0.71
110_Q	122_C	0.561	0.71
65_F	96_P	0.553	0.70
47_V	109_V	0.552	0.70
50_T	123_V	0.551	0.70
63_V	116_L	0.543	0.69
35_G	61_F	0.538	0.68
104_T	107_D	0.534	0.67
114_D	123_V	0.531	0.67
37_C	65_F	0.524	0.66
23_I	51_V	0.518	0.65
108_N	116_L	0.518	0.65
84_H	87_F	0.517	0.65
112_Y	117_E	0.515	0.65
30_P	88_S	0.507	0.63
109_V	122_C	0.507	0.63
45_Y	133_S	0.505	0.63
66_S	70_K	0.504	0.63
17_L	26_A	0.503	0.63
17_L	135_C	0.503	0.63
54_D	111_A	0.501	0.63
106_Y	130_T	0.500	0.62
64_N	78_H	0.500	0.62

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3d7jA	4	0.8699	100	0.25	Contact Map
1b66A	4	0.8425	100	0.261	Contact Map
2g64A	4	0.863	100	0.267	Contact Map
2obaA	4	0.8014	100	0.279	Contact Map
4ntkA	4	0.7945	100	0.285	Contact Map
3jygA	4	0.8562	100	0.285	Contact Map
1y13A	5	0.8699	100	0.307	Contact Map
3lx3A	4	0.8699	100	0.309	Contact Map
2dj6A	3	0.7671	100	0.315	Contact Map
1gqpA	2	0.5342	10.7	0.946	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0063 seconds.