GREMLIN Database
CLPE - ATP-dependent Clp protease ATP-binding subunit ClpE
UniProt: O31673 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 699 (632)
Sequences: 4864 (2190)
Seq/√Len: 87.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
83_N87_A5.7611.00
80_N149_E5.2291.00
619_S643_K5.2131.00
78_A151_Y4.5831.00
611_K648_E4.1481.00
639_T690_E4.1381.00
615_V644_E4.0721.00
343_N346_L3.9631.00
257_A285_V3.8421.00
675_L680_G3.7541.00
402_E405_A3.6731.00
408_H415_E3.3771.00
539_R547_T3.3751.00
254_I285_V3.3241.00
361_L364_S3.2291.00
406_K409_E3.1521.00
156_A210_I3.1331.00
79_Q84_G3.0181.00
557_M600_F2.9971.00
258_I281_I2.9881.00
441_S535_M2.9381.00
641_E690_E2.9231.00
180_K219_E2.8781.00
163_G167_Q2.7471.00
403_L462_E2.7401.00
346_L349_K2.5881.00
423_K670_D2.5821.00
373_E376_H2.5571.00
253_S256_Q2.5251.00
610_E613_H2.5221.00
72_G75_D2.4711.00
103_V247_V2.4671.00
177_T181_E2.4251.00
116_V192_I2.3851.00
276_F309_G2.3851.00
423_K674_D2.3651.00
71_K75_D2.3461.00
327_R353_E2.3361.00
106_I247_V2.3181.00
577_S580_E2.2941.00
443_L600_F2.2881.00
412_I620_L2.2741.00
358_E362_N2.2601.00
192_I234_I2.2391.00
254_I289_S2.2111.00
158_L175_L2.2051.00
404_E419_Q2.1841.00
623_G626_E2.1801.00
143_N146_K2.1431.00
611_K644_E2.1431.00
445_V559_S2.1271.00
343_N347_A2.1231.00
482_H491_P2.1181.00
622_L638_V2.0951.00
349_K353_E2.0891.00
259_L262_Q2.0881.00
344_Y347_A2.0661.00
639_T688_I2.0651.00
649_L667_W2.0571.00
561_A591_F2.0441.00
645_K691_D2.0331.00
343_N361_L2.0221.00
406_K462_E2.0131.00
645_K649_L2.0031.00
346_L353_E1.9981.00
614_L647_A1.9871.00
331_I350_L1.9821.00
282_K286_T1.9761.00
84_G89_L1.9681.00
304_L381_V1.9611.00
404_E426_R1.9511.00
394_A402_E1.9301.00
418_V455_L1.9281.00
456_S556_I1.9211.00
410_R461_D1.9191.00
625_L664_I1.9191.00
463_L554_V1.9191.00
646_I663_T1.9131.00
481_K526_D1.9001.00
471_I513_S1.8731.00
312_A372_V1.8321.00
283_A374_A1.8281.00
90_I134_L1.8221.00
410_R454_E1.7971.00
362_N366_A1.7911.00
80_N83_N1.7811.00
410_R458_T1.7741.00
196_V240_L1.7731.00
139_G146_K1.7731.00
80_N151_Y1.7681.00
668_V689_L1.7651.00
359_K363_S1.7601.00
681_E687_V1.7431.00
607_R613_H1.7401.00
435_K628_T1.7361.00
621_L661_R1.7331.00
630_A635_S1.7291.00
663_T667_W1.7241.00
284_C305_L1.7221.00
588_L597_L1.7171.00
534_I555_I1.7131.00
73_L174_Q1.7131.00
615_V640_D1.7081.00
410_R467_K1.6961.00
233_Q499_E1.6861.00
266_D270_A1.6851.00
361_L365_S1.6711.00
254_I286_T1.6701.00
561_A588_L1.6691.00
637_N686_H1.6671.00
262_Q278_D1.6641.00
637_N688_I1.6601.00
482_H485_S1.6361.00
177_T180_K1.6271.00
507_V553_T1.6241.00
401_K678_D1.6201.00
83_N86_K1.6191.00
531_F534_I1.6181.00
534_I540_L1.5931.00
401_K677_L1.5841.00
335_K354_E1.5741.00
360_K364_S1.5741.00
585_I588_L1.5651.00
254_I258_I1.5641.00
587_S590_M1.5631.00
634_I687_V1.5621.00
408_H418_V1.5561.00
250_Q510_N1.5541.00
353_E356_A1.5521.00
275_T371_T1.5511.00
621_L624_E1.5451.00
345_E349_K1.5391.00
155_V158_L1.5341.00
343_N349_K1.5311.00
248_M510_N1.5281.00
642_A691_D1.5271.00
189_I222_V1.5261.00
328_L357_L1.5191.00
645_K667_W1.5121.00
618_V647_A1.5101.00
264_I267_K1.5061.00
356_A360_K1.5061.00
416_A607_R1.5021.00
348_A352_D1.5011.00
618_V643_K1.4971.00
265_K278_D1.4921.00
632_R683_T1.4870.99
416_A581_E1.4850.99
682_I685_F1.4820.99
638_V643_K1.4740.99
635_S686_H1.4730.99
319_L325_A1.4570.99
355_L359_K1.4560.99
102_R307_E1.4460.99
444_F556_I1.4430.99
479_M483_A1.4210.99
633_G683_T1.4140.99
639_T642_A1.4100.99
480_E491_P1.4060.99
347_A351_R1.3990.99
345_E348_A1.3960.99
403_L422_A1.3920.99
328_L361_L1.3900.99
343_N364_S1.3850.99
672_M687_V1.3760.99
471_I507_V1.3590.99
638_V642_A1.3510.99
91_D110_R1.3500.99
469_A510_N1.3480.99
615_V643_K1.3410.99
286_T631_E1.3350.99
348_A351_R1.3330.99
192_I224_G1.3330.99
343_N353_E1.3320.99
354_E358_E1.3320.99
443_L588_L1.3270.99
176_I214_A1.3200.99
346_L354_E1.3140.99
86_K149_E1.3140.99
326_E330_A1.3110.99
577_S581_E1.3040.99
338_A347_A1.3000.99
136_I150_L1.2980.99
613_H616_K1.2950.99
470_I514_I1.2930.99
135_K140_D1.2920.99
257_A297_L1.2920.99
402_E406_K1.2890.99
262_Q282_K1.2850.99
258_I282_K1.2800.98
297_L301_A1.2780.98
336_T339_L1.2640.98
128_I249_V1.2600.98
664_I668_V1.2600.98
328_L354_E1.2590.98
327_R330_A1.2480.98
344_Y348_A1.2480.98
622_L664_I1.2450.98
479_M526_D1.2440.98
288_S297_L1.2410.98
420_K604_I1.2350.98
419_Q423_K1.2280.98
536_E661_R1.2230.98
616_K619_S1.2220.98
120_E228_L1.2220.98
279_E374_A1.2180.98
346_L350_L1.2130.98
134_L138_E1.2110.98
277_S371_T1.2070.98
671_E675_L1.2060.98
232_R544_Q1.2060.98
625_L669_E1.2040.98
334_E346_L1.2030.98
72_G178_E1.2020.98
428_S433_K1.2020.98
649_L663_T1.1990.98
353_E361_L1.1980.98
262_Q265_K1.1980.98
200_S204_S1.1970.98
172_M175_L1.1960.98
507_V550_F1.1960.98
324_A357_L1.1960.98
675_L681_E1.1930.98
323_D327_R1.1890.98
473_L487_I1.1840.97
102_R105_E1.1820.97
650_G660_L1.1760.97
581_E585_I1.1750.97
582_Q586_D1.1740.97
108_N144_K1.1720.97
105_E310_S1.1700.97
357_L361_L1.1690.97
332_E335_K1.1650.97
619_S640_D1.1600.97
634_I681_E1.1590.97
69_E72_G1.1550.97
347_A361_L1.1510.97
623_G627_E1.1500.97
82_T137_A1.1460.97
256_Q259_L1.1430.97
517_L534_I1.1420.97
182_R185_V1.1400.97
281_I305_L1.1390.97
292_I381_V1.1290.97
407_L411_V1.1270.97
485_S488_I1.1240.96
670_D674_D1.1230.96
64_A70_K1.1160.96
415_E613_H1.1120.96
334_E337_K1.1110.96
75_D83_N1.1100.96
288_S300_K1.1070.96
93_V100_V1.1070.96
330_A334_E1.1070.96
404_E408_H1.1060.96
578_V581_E1.1060.96
638_V668_V1.1050.96
261_L284_C1.1050.96
346_L361_L1.1050.96
277_S280_A1.1020.96
675_L678_D1.1020.96
432_L625_L1.0990.96
379_E390_G1.0990.96
577_S607_R1.0980.96
615_V619_S1.0950.96
443_L520_I1.0930.96
667_W671_E1.0880.96
121_P241_E1.0880.96
262_Q281_I1.0870.96
277_S373_E1.0830.96
359_K362_N1.0830.96
484_V527_V1.0780.96
641_E691_D1.0770.96
179_L187_L1.0770.96
652_H659_P1.0690.95
82_T90_I1.0670.95
103_V129_A1.0660.95
251_E289_S1.0620.95
162_T175_L1.0610.95
118_I246_P1.0610.95
401_K674_D1.0610.95
134_L137_A1.0590.95
488_I530_M1.0590.95
426_R674_D1.0580.95
73_L178_E1.0490.95
105_E311_K1.0480.95
618_V664_I1.0480.95
434_S628_T1.0450.95
201_A205_M1.0450.95
641_E644_E1.0420.95
85_A90_I1.0410.95
258_I285_V1.0380.95
337_K341_E1.0370.95
490_S517_L1.0360.94
640_D644_E1.0340.94
332_E336_T1.0340.94
626_E630_A1.0330.94
329_T332_E1.0300.94
626_E638_V1.0220.94
497_H543_S1.0200.94
566_K570_V1.0200.94
312_A376_H1.0080.94
444_F606_F1.0080.94
351_R354_E1.0060.94
564_G587_S1.0040.93
650_G663_T1.0020.93
405_A408_H1.0020.93
580_E607_R0.9990.93
504_T548_V0.9950.93
458_T461_D0.9920.93
478_Y502_Q0.9910.93
681_E685_F0.9900.93
335_K339_L0.9900.93
311_K379_E0.9870.93
581_E605_E0.9870.93
331_I357_L0.9860.93
343_N354_E0.9850.93
565_E587_S0.9850.93
400_M429_R0.9830.93
283_A286_T0.9830.93
101_A315_L0.9820.93
110_R267_K0.9800.93
479_M529_H0.9790.93
644_E648_E0.9750.92
98_D383_Q0.9740.92
265_K281_I0.9720.92
346_L364_S0.9710.92
332_E358_E0.9700.92
626_E636_L0.9690.92
121_P296_H0.9670.92
404_E422_A0.9670.92
331_I354_E0.9660.92
100_V131_G0.9620.92
576_D579_I0.9610.92
353_E358_E0.9600.92
229_K232_R0.9570.92
347_A353_E0.9570.92
270_A273_G0.9550.92
622_L668_V0.9520.92
396_E429_R0.9500.91
135_K326_E0.9500.91
358_E361_L0.9480.91
484_V530_M0.9470.91
110_R268_Y0.9470.91
176_I210_I0.9460.91
645_K648_E0.9440.91
77_L162_T0.9420.91
325_A329_T0.9390.91
398_T402_E0.9390.91
271_Y313_N0.9380.91
116_V234_I0.9380.91
82_T85_A0.9340.91
454_E458_T0.9300.91
434_S551_K0.9280.91
433_K439_V0.9240.90
325_A365_S0.9210.90
437_R661_R0.9210.90
360_K363_S0.9190.90
144_K317_D0.9180.90
358_E363_S0.9130.90
473_L486_K0.9110.90
352_D355_L0.9100.90
425_V554_V0.9080.90
408_H613_H0.9040.89
411_V472_R0.9030.89
585_I605_E0.9010.89
433_K549_S0.9010.89
118_I228_L0.8990.89
97_D135_K0.8990.89
508_R546_R0.8990.89
62_Q68_S0.8970.89
376_H379_E0.8940.89
454_E621_L0.8930.89
436_N467_K0.8880.88
344_Y361_L0.8870.88
313_N317_D0.8870.88
418_V422_A0.8870.88
117_L249_V0.8860.88
344_Y351_R0.8850.88
602_S665_Q0.8850.88
288_S304_L0.8850.88
611_K647_A0.8840.88
321_D324_A0.8840.88
350_L354_E0.8830.88
588_L603_I0.8820.88
408_H419_Q0.8810.88
362_N365_S0.8790.88
349_K354_E0.8780.88
63_S67_Q0.8780.88
168_F207_A0.8770.88
328_L332_E0.8760.88
643_K660_L0.8750.88
333_A337_K0.8740.88
561_A587_S0.8730.88
549_S552_D0.8730.88
108_N310_S0.8720.88
305_L377_I0.8710.87
352_D356_A0.8690.87
490_S499_E0.8680.87
486_K543_S0.8680.87
415_E419_Q0.8680.87
375_E379_E0.8640.87
258_I286_T0.8620.87
155_V195_L0.8620.87
457_K537_D0.8610.87
612_E615_V0.8600.87
615_V647_A0.8590.87
481_K486_K0.8570.87
79_Q180_K0.8560.87
532_L595_E0.8540.86
345_E361_L0.8540.86
669_E673_T0.8540.86
506_K510_N0.8540.86
353_E360_K0.8530.86
228_L248_M0.8520.86
520_I557_M0.8520.86
342_E351_R0.8510.86
434_S624_E0.8500.86
435_K631_E0.8490.86
624_E627_E0.8490.86
112_K303_D0.8490.86
408_H607_R0.8470.86
280_A374_A0.8440.86
172_M211_L0.8440.86
153_L175_L0.8420.86
619_S623_G0.8410.86
579_I583_T0.8410.86
424_A439_V0.8410.86
129_A223_I0.8400.86
121_P238_A0.8390.85
642_A690_E0.8390.85
347_A360_K0.8390.85
81_I152_L0.8380.85
614_L651_Y0.8380.85
597_L603_I0.8360.85
619_S638_V0.8340.85
622_L626_E0.8340.85
201_A204_S0.8320.85
77_L171_R0.8290.85
598_N662_R0.8270.85
507_V515_V0.8270.85
564_G568_T0.8250.85
639_T691_D0.8250.85
433_K669_E0.8240.84
629_L633_G0.8220.84
472_R537_D0.8220.84
354_E361_L0.8220.84
495_V498_E0.8200.84
380_I384_K0.8180.84
407_L458_T0.8170.84
627_E631_E0.8170.84
611_K651_Y0.8140.84
162_T172_M0.8140.84
68_S71_K0.8130.84
308_A380_I0.8100.83
627_E630_A0.8100.83
324_A361_L0.8090.83
646_I667_W0.8090.83
154_D157_S0.8080.83
356_A361_L0.8050.83
642_A668_V0.8030.83
359_K366_A0.8020.83
418_V421_V0.8020.83
596_F600_F0.8010.83
473_L517_L0.8000.83
202_E205_M0.7980.82
592_F596_F0.7980.82
206_D209_N0.7980.82
467_K537_D0.7970.82
267_K270_A0.7960.82
86_K137_A0.7960.82
422_A426_R0.7960.82
281_I285_V0.7950.82
110_R432_L0.7950.82
327_R360_K0.7940.82
147_N184_N0.7930.82
628_T669_E0.7930.82
345_E352_D0.7920.82
630_A633_G0.7880.82
153_L158_L0.7830.81
536_E596_F0.7830.81
312_A315_L0.7830.81
195_L208_G0.7810.81
642_A689_L0.7800.81
346_L360_K0.7760.81
634_I676_L0.7750.81
455_L606_F0.7730.80
619_S626_E0.7730.80
277_S376_H0.7720.80
621_L660_L0.7720.80
473_L515_V0.7710.80
412_I616_K0.7700.80
374_A391_K0.7680.80
325_A361_L0.7620.80
176_I211_L0.7610.79
358_E366_A0.7580.79
626_E635_S0.7560.79
483_A486_K0.7560.79
62_Q67_Q0.7550.79
310_S317_D0.7540.79
419_Q422_A0.7540.79
354_E360_K0.7530.79
355_L361_L0.7520.79
584_L605_E0.7520.79
480_E485_S0.7500.78
674_D678_D0.7500.78
426_R670_D0.7490.78
66_K69_E0.7490.78
132_L136_I0.7490.78
530_M540_L0.7490.78
156_A222_V0.7480.78
427_R670_D0.7470.78
534_I553_T0.7470.78
466_T469_A0.7470.78
646_I668_V0.7460.78
569_K572_F0.7440.78
566_K580_E0.7430.78
415_E616_K0.7420.78
472_R536_E0.7410.78
504_T540_L0.7410.78
579_I582_Q0.7400.77
400_M426_R0.7390.77
371_T376_H0.7380.77
638_V689_L0.7350.77
490_S543_S0.7350.77
64_A68_S0.7350.77
179_L182_R0.7330.77
254_I257_A0.7330.77
246_P294_D0.7320.77
187_L220_L0.7300.77
339_L342_E0.7290.76
517_L557_M0.7280.76
421_V444_F0.7280.76
378_Q389_V0.7270.76
636_L668_V0.7260.76
637_N640_D0.7260.76
224_G234_I0.7250.76
350_L353_E0.7250.76
292_I300_K0.7220.76
395_D398_T0.7210.76
103_V128_I0.7210.76
69_E75_D0.7200.76
110_R113_N0.7200.76
407_L418_V0.7190.75
328_L331_I0.7170.75
421_V455_L0.7160.75
643_K647_A0.7160.75
338_A341_E0.7130.75
645_K663_T0.7130.75
335_K351_R0.7130.75
324_A328_L0.7120.75
64_A67_Q0.7110.75
202_E233_Q0.7100.75
505_E509_R0.7070.74
486_K502_Q0.7070.74
76_E162_T0.7060.74
63_S68_S0.7050.74
275_T369_A0.7050.74
172_M207_A0.7030.74
344_Y354_E0.7030.74
332_E354_E0.7030.74
479_M530_M0.7020.74
539_R551_K0.7010.74
355_L358_E0.7010.74
405_A409_E0.7010.74
311_K383_Q0.7000.73
92_P267_K0.7000.73
347_A354_E0.6990.73
569_K583_T0.6990.73
346_L358_E0.6990.73
437_R536_E0.6990.73
479_M543_S0.6970.73
447_P559_S0.6970.73
338_A344_Y0.6960.73
93_V551_K0.6930.73
105_E307_E0.6930.73
311_K315_L0.6920.73
479_M484_V0.6920.73
479_M669_E0.6910.73
420_K602_S0.6890.72
440_G445_V0.6890.72
495_V543_S0.6880.72
228_L509_R0.6880.72
445_V588_L0.6880.72
423_K666_E0.6870.72
191_E230_E0.6860.72
636_L689_L0.6850.72
129_A134_L0.6850.72
331_I335_K0.6850.72
120_E129_A0.6850.72
179_L185_V0.6830.72
427_R669_E0.6810.71
116_V241_E0.6770.71
629_L634_I0.6750.71
262_Q334_E0.6740.71
76_E174_Q0.6740.71
409_E623_G0.6740.71
168_F199_G0.6730.71
345_E351_R0.6710.70
82_T150_L0.6700.70
158_L187_L0.6700.70
486_K541_T0.6690.70
349_K360_K0.6670.70
382_E389_V0.6660.70
626_E634_I0.6630.69
335_K347_A0.6620.69
308_A377_I0.6610.69
278_D282_K0.6600.69
583_T586_D0.6600.69
592_F600_F0.6590.69
520_I561_A0.6580.69
650_G659_P0.6560.69
324_A360_K0.6560.69
71_K151_Y0.6560.69
478_Y486_K0.6550.68
354_E357_L0.6540.68
335_K352_D0.6540.68
688_I691_D0.6530.68
163_G170_E0.6520.68
346_L359_K0.6520.68
461_D467_K0.6510.68
550_F555_I0.6490.68
213_P226_T0.6490.68
162_T165_R0.6470.68
241_E246_P0.6470.68
93_V264_I0.6460.67
333_A336_T0.6460.67
334_E338_A0.6460.67
329_T333_A0.6450.67
336_T340_E0.6430.67
626_E629_L0.6430.67
277_S374_A0.6420.67
386_G504_T0.6410.67
85_A110_R0.6400.67
282_K374_A0.6390.67
651_Y663_T0.6380.66
342_E352_D0.6380.66
471_I506_K0.6380.66
443_L673_T0.6380.66
327_R357_L0.6370.66
101_A317_D0.6370.66
295_R384_K0.6360.66
150_L179_L0.6360.66
550_F553_T0.6350.66
408_H426_R0.6340.66
180_K214_A0.6340.66
535_M555_I0.6340.66
319_L322_E0.6330.66
578_V582_Q0.6310.66
118_I509_R0.6300.65
470_I513_S0.6290.65
668_V675_L0.6290.65
486_K549_S0.6290.65
529_H593_K0.6280.65
602_S666_E0.6280.65
280_A283_A0.6270.65
82_T271_Y0.6270.65
197_G206_D0.6260.65
274_V372_V0.6250.65
577_S605_E0.6250.65
473_L530_M0.6240.65
345_E353_E0.6220.65
359_K365_S0.6220.65
633_G686_H0.6210.64
268_Y303_D0.6200.64
470_I515_V0.6190.64
389_V393_Q0.6180.64
217_R225_A0.6180.64
139_G147_N0.6160.64
372_V380_I0.6160.64
400_M404_E0.6150.64
347_A355_L0.6150.64
90_I138_E0.6150.64
587_S591_F0.6150.64
304_L377_I0.6140.64
112_K268_Y0.6130.63
565_E583_T0.6130.63
309_G540_L0.6130.63
305_L309_G0.6120.63
72_G151_Y0.6120.63
416_A419_Q0.6110.63
412_I613_H0.6100.63
259_L330_A0.6100.63
247_V525_P0.6100.63
589_S655_F0.6090.63
148_K221_Q0.6080.63
67_Q70_K0.6070.63
482_H486_K0.6070.63
425_V459_L0.6060.63
525_P593_K0.6060.63
641_E692_D0.6050.62
222_V244_F0.6040.62
75_D151_Y0.6030.62
191_E227_T0.6030.62
623_G638_V0.6020.62
586_D589_S0.6020.62
473_L527_V0.6010.62
479_M488_I0.6010.62
333_A341_E0.6010.62
154_D173_K0.6010.62
381_V389_V0.6000.62
339_L347_A0.6000.62
220_L289_S0.5990.62
143_N317_D0.5990.62
197_G209_N0.5990.62
613_H660_L0.5990.62
498_E544_Q0.5990.62
63_S66_K0.5990.62
97_D256_Q0.5990.62
354_E364_S0.5980.61
62_Q65_A0.5970.61
351_R355_L0.5970.61
432_L672_M0.5970.61
90_I93_V0.5960.61
229_K233_Q0.5960.61
92_P264_I0.5950.61
357_L360_K0.5950.61
279_E282_K0.5940.61
408_H412_I0.5930.61
265_K276_F0.5930.61
155_V205_M0.5920.61
268_Y614_L0.5900.60
453_T536_E0.5900.60
159_V165_R0.5890.60
636_L643_K0.5890.60
198_A201_A0.5880.60
98_D323_D0.5880.60
521_E532_L0.5870.60
353_E364_S0.5870.60
102_R111_N0.5870.60
81_I90_I0.5860.60
437_R601_D0.5860.60
571_G574_S0.5850.60
663_T677_L0.5840.60
349_K355_L0.5840.60
519_E522_K0.5830.60
381_V556_I0.5830.60
62_Q71_K0.5830.60
567_Q572_F0.5830.60
520_I592_F0.5830.60
167_Q608_S0.5820.59
450_V479_M0.5810.59
101_A311_K0.5800.59
519_E560_N0.5790.59
120_E229_K0.5790.59
150_L223_I0.5770.59
326_E329_T0.5760.59
349_K352_D0.5760.59
168_F197_G0.5760.59
195_L214_A0.5740.58
492_P499_E0.5730.58
339_L344_Y0.5730.58
407_L422_A0.5730.58
428_S439_V0.5720.58
537_D547_T0.5720.58
164_I170_E0.5710.58
355_L366_A0.5710.58
327_R331_I0.5710.58
349_K358_E0.5710.58
623_G644_E0.5710.58
436_N468_D0.5710.58
130_E217_R0.5700.58
408_H458_T0.5700.58
646_I650_G0.5700.58
468_D510_N0.5700.58
283_A287_L0.5690.58
661_R665_Q0.5670.57
353_E357_L0.5670.57
334_E350_L0.5670.57
586_D590_M0.5670.57
405_A637_N0.5660.57
646_I660_L0.5660.57
106_I510_N0.5660.57
61_E67_Q0.5650.57
94_I263_G0.5650.57
408_H422_A0.5650.57
188_F225_A0.5640.57
81_I129_A0.5640.57
149_E184_N0.5640.57
659_P662_R0.5630.57
363_S366_A0.5630.57
103_V249_V0.5610.57
216_A287_L0.5610.57
78_A232_R0.5600.57
346_L355_L0.5600.57
89_L219_E0.5600.57
458_T467_K0.5590.56
179_L195_L0.5580.56
216_A274_V0.5580.56
355_L360_K0.5580.56
118_I248_M0.5570.56
342_E345_E0.5570.56
426_R677_L0.5570.56
349_K361_L0.5550.56
434_S610_E0.5550.56
520_I591_F0.5540.56
261_L301_A0.5540.56
430_A677_L0.5540.56
136_I147_N0.5540.56
425_V439_V0.5530.56
85_A134_L0.5530.56
71_K178_E0.5520.55
165_R199_G0.5520.55
347_A350_L0.5500.55
293_Q551_K0.5500.55
127_A213_P0.5500.55
530_M596_F0.5500.55
672_M677_L0.5490.55
150_L183_K0.5490.55
448_T598_N0.5490.55
234_I241_E0.5480.55
283_A304_L0.5470.55
155_V240_L0.5470.55
445_V561_A0.5460.55
97_D101_A0.5460.55
436_N443_L0.5460.55
264_I657_A0.5450.55
296_H300_K0.5450.55
170_E174_Q0.5450.55
488_I541_T0.5450.55
314_L443_L0.5440.54
195_L329_T0.5440.54
73_L157_S0.5440.54
551_K628_T0.5440.54
565_E584_L0.5440.54
186_I540_L0.5440.54
226_T239_A0.5440.54
255_E640_D0.5440.54
163_G206_D0.5430.54
226_T243_R0.5430.54
78_A392_L0.5420.54
342_E347_A0.5420.54
257_A261_L0.5420.54
454_E537_D0.5410.54
475_M606_F0.5400.54
86_K581_E0.5400.54
199_G203_G0.5390.54
426_R646_I0.5390.54
565_E568_T0.5390.54
665_Q670_D0.5390.54
386_G510_N0.5380.54
292_I296_H0.5370.53
518_D560_N0.5350.53
357_L639_T0.5350.53
193_H226_T0.5350.53
63_S71_K0.5350.53
382_E392_L0.5340.53
411_V458_T0.5340.53
338_A346_L0.5330.53
622_L636_L0.5330.53
106_I192_I0.5330.53
121_P231_Y0.5320.53
634_I683_T0.5320.53
583_T587_S0.5320.53
132_L228_L0.5320.53
167_Q251_E0.5320.53
478_Y487_I0.5310.53
393_Q672_M0.5290.52
592_F597_L0.5290.52
485_S682_I0.5290.52
369_A636_L0.5290.52
171_R440_G0.5290.52
165_R202_E0.5280.52
353_E365_S0.5280.52
233_Q498_E0.5280.52
476_S497_H0.5270.52
154_D211_L0.5270.52
61_E64_A0.5270.52
532_L541_T0.5270.52
517_L531_F0.5260.52
397_Q401_K0.5260.52
540_L543_S0.5250.52
344_Y352_D0.5250.52
346_L351_R0.5230.52
618_V660_L0.5230.52
485_S543_S0.5230.52
443_L557_M0.5230.52
671_E681_E0.5230.52
585_I589_S0.5220.51
258_I262_Q0.5210.51
472_R532_L0.5200.51
421_V424_A0.5200.51
304_L385_T0.5200.51
150_L187_L0.5190.51
216_A220_L0.5190.51
101_A383_Q0.5180.51
261_L281_I0.5180.51
479_M486_K0.5180.51
630_A682_I0.5180.51
172_M506_K0.5180.51
539_R660_L0.5170.51
327_R363_S0.5170.51
481_K488_I0.5170.51
262_Q320_N0.5170.51
144_K313_N0.5160.51
200_S233_Q0.5160.51
403_L411_V0.5160.51
622_L643_K0.5160.51
79_Q152_L0.5160.51
588_L604_I0.5160.51
173_K177_T0.5150.50
84_G179_L0.5150.50
580_E605_E0.5150.50
64_A170_E0.5150.50
518_D599_R0.5150.50
270_A369_A0.5150.50
649_L666_E0.5150.50
356_A364_S0.5130.50
531_F535_M0.5130.50
132_L261_L0.5120.50
104_I135_K0.5120.50
210_I222_V0.5120.50
158_L222_V0.5120.50
236_K544_Q0.5120.50
234_I471_I0.5110.50
378_Q384_K0.5110.50
75_D78_A0.5110.50
304_L618_V0.5110.50
534_I550_F0.5110.50
440_G625_L0.5100.50
517_L608_S0.5100.50
462_E620_L0.5100.50
283_A288_S0.5090.50
225_A243_R0.5090.50
519_E599_R0.5090.50
347_A352_D0.5090.50
129_A195_L0.5080.50
582_Q603_I0.5080.50
473_L478_Y0.5080.50
84_G87_A0.5080.50
163_G531_F0.5070.49
176_I180_K0.5070.49
293_Q549_S0.5070.49
434_S437_R0.5070.49
193_H230_E0.5050.49
138_E325_A0.5050.49
183_K205_M0.5050.49
653_P659_P0.5050.49
580_E625_L0.5040.49
281_I387_I0.5040.49
265_K269_E0.5040.49
568_T571_G0.5030.49
400_M679_N0.5030.49
189_I497_H0.5030.49
681_E684_S0.5020.49
435_K592_F0.5010.49
560_N599_R0.5010.49
387_I476_S0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qvrA 3 0.9113 100 0.491 Contact Map
1r6bX 1 0.8526 100 0.495 Contact Map
4d2uA 3 0.9113 100 0.503 Contact Map
3pxiA 3 0.8484 100 0.535 Contact Map
4ciuA 1 0.8484 100 0.556 Contact Map
3vkgA 2 0.8655 100 0.742 Contact Map
4hseA 1 0.4378 100 0.786 Contact Map
4lj9A 1 0.4721 100 0.798 Contact Map
3pxgA 3 0.4621 100 0.799 Contact Map
4akgA 2 0.8641 100 0.814 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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