GREMLIN Database
KINE - Sporulation kinase E
UniProt: O31661 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 738 (582)
Sequences: 3102 (2722)
Seq/√Len: 112.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
284_D376_R5.3891.00
539_I557_I5.2791.00
163_D256_R5.0621.00
404_D496_K4.8491.00
392_E396_R3.8601.00
714_E717_K3.5151.00
287_I373_T3.5001.00
285_A305_I3.4841.00
710_M722_H3.4111.00
711_V721_F3.2361.00
326_Q347_L3.2071.00
187_I231_R3.1501.00
272_E276_R3.1251.00
308_L351_G3.0791.00
381_R385_E2.9541.00
345_E382_K2.9251.00
262_R265_E2.8611.00
312_L351_G2.8411.00
359_E376_R2.7561.00
279_F297_K2.7531.00
662_I723_I2.7481.00
239_E256_R2.7091.00
367_L370_Q2.6941.00
367_L371_H2.6791.00
225_E262_R2.6521.00
641_V685_T2.6331.00
665_K720_V2.6241.00
502_K505_E2.5911.00
407_V493_A2.5311.00
399_F417_D2.5061.00
699_Y703_E2.4751.00
166_V174_F2.4561.00
158_F176_D2.4471.00
405_G425_I2.4091.00
323_V347_L2.3841.00
191_E231_R2.3781.00
230_L234_V2.3601.00
161_A165_I2.3431.00
405_G495_F2.3051.00
661_L722_H2.2911.00
479_E496_K2.2861.00
642_M667_E2.2761.00
676_L711_V2.2721.00
261_K265_E2.2681.00
428_L471_S2.2581.00
301_S304_K2.2571.00
285_A375_L2.2311.00
487_I490_M2.2291.00
672_T675_K2.2241.00
164_G255_M2.2231.00
350_M354_Q2.2171.00
698_S709_I2.1971.00
583_E624_P2.1801.00
151_E155_K2.1771.00
382_K385_E2.1661.00
323_V326_Q2.1181.00
671_M675_K2.1081.00
505_E509_R2.0351.00
164_G184_S2.0021.00
159_D179_L1.9991.00
465_E502_K1.9951.00
275_F279_F1.9921.00
169_D173_G1.9781.00
630_V702_I1.9671.00
177_A181_F1.9561.00
287_I295_I1.9261.00
276_R280_E1.8791.00
392_E395_F1.8651.00
391_S394_K1.8621.00
432_E471_S1.8491.00
501_R505_E1.8471.00
230_L236_K1.8421.00
223_K239_E1.8271.00
166_V253_S1.8221.00
182_C189_H1.8141.00
179_L183_K1.8071.00
164_G181_F1.8011.00
585_K622_C1.7931.00
536_K561_L1.7891.00
282_A286_I1.7801.00
522_A527_E1.7731.00
630_V698_S1.7711.00
177_A182_C1.7461.00
508_L511_S1.7441.00
565_E569_T1.7381.00
537_G541_L1.7321.00
436_H440_D1.7101.00
630_V701_I1.6961.00
470_L474_D1.6931.00
343_R359_E1.6801.00
622_C705_H1.6751.00
402_S406_N1.6621.00
711_V719_T1.6591.00
702_I723_I1.6581.00
385_E389_R1.6511.00
347_L357_E1.6471.00
546_V550_Y1.6431.00
272_E275_F1.6371.00
642_M648_I1.6371.00
347_L355_F1.6331.00
407_V415_I1.6221.00
640_E685_T1.6201.00
285_A302_A1.6201.00
258_I262_R1.6161.00
504_L508_L1.6091.00
288_I299_N1.6011.00
391_S395_F1.5991.00
487_I491_N1.5921.00
267_Q271_S1.5841.00
651_T663_S1.5721.00
302_A306_F1.5701.00
346_L360_F1.5581.00
309_P312_L1.5571.00
671_M679_L1.5551.00
527_E531_P1.5521.00
175_I250_F1.5521.00
187_I191_E1.5451.00
410_D414_R1.5371.00
350_M356_K1.5311.00
610_Q647_N1.5251.00
586_H589_Q1.5201.00
612_D649_F1.5191.00
395_F398_V1.5161.00
418_A423_S1.5141.00
154_F158_F1.5131.00
584_E621_Y1.5021.00
395_F399_F1.4941.00
285_A299_N1.4931.00
701_I705_H1.4811.00
181_F185_F1.4711.00
443_S446_E1.4691.00
271_S274_R1.4651.00
298_A303_C1.4641.00
543_K558_T1.4571.00
168_F253_S1.4541.00
308_L312_L1.4511.00
242_I251_Y1.4471.00
517_V521_A1.4351.00
547_E550_Y1.4351.00
479_E501_R1.4281.00
279_F299_N1.4231.00
188_N191_E1.4221.00
180_S183_K1.4151.00
166_V181_F1.4141.00
680_G709_I1.4071.00
289_W333_K1.4011.00
323_V355_F1.4001.00
642_M646_G1.3951.00
359_E381_R1.3931.00
506_E509_R1.3821.00
631_F662_I1.3791.00
672_T715_E1.3751.00
661_L724_T1.3701.00
446_E467_P1.3661.00
634_I664_L1.3641.00
602_A648_I1.3591.00
456_Q461_E1.3591.00
386_K389_R1.3581.00
503_E507_R1.3531.00
195_L199_E1.3511.00
419_N497_D1.3501.00
673_E676_L1.3461.00
388_L391_S1.3451.00
239_E261_K1.3441.00
429_S432_E1.3381.00
646_G667_E1.3351.00
244_S250_F1.3311.00
542_L554_F1.3311.00
378_V382_K1.3281.00
534_A560_E1.3221.00
420_P423_S1.3191.00
279_F286_I1.3181.00
420_P424_H1.3121.00
168_F242_I1.3101.00
428_L432_E1.3081.00
588_T652_I1.2940.99
525_A530_N1.2920.99
538_F553_Y1.2920.99
507_R510_K1.2880.99
470_L476_R1.2870.99
300_Q304_K1.2870.99
527_E567_I1.2840.99
659_H724_T1.2830.99
150_N153_L1.2830.99
290_S294_R1.2790.99
265_E269_F1.2780.99
543_K555_N1.2770.99
167_L250_F1.2760.99
289_W293_G1.2710.99
679_L721_F1.2640.99
391_S396_R1.2600.99
155_K159_D1.2600.99
154_F157_L1.2570.99
542_L550_Y1.2460.99
196_S199_E1.2410.99
271_S275_F1.2390.99
419_N422_A1.2390.99
287_I302_A1.2350.99
268_L271_S1.2320.99
612_D651_T1.2310.99
591_M650_V1.2300.99
663_S720_V1.2280.99
407_V422_A1.2250.99
298_A302_A1.2210.99
467_P477_K1.2140.99
702_I707_G1.2140.99
215_A218_R1.2130.99
289_W362_S1.2130.99
177_A192_L1.2100.99
283_M299_N1.2090.99
666_D670_G1.2080.99
269_F272_E1.2060.99
176_D189_H1.2040.99
299_N302_A1.2040.99
713_S719_T1.2030.99
360_F375_L1.2030.99
168_F197_L1.2010.99
271_S276_R1.1970.99
467_P475_N1.1910.99
205_S227_P1.1840.99
598_L635_L1.1820.99
173_G196_S1.1800.99
179_L182_C1.1740.99
610_Q649_F1.1710.99
336_Y364_R1.1650.99
626_Q629_Q1.1610.99
476_R497_D1.1580.99
237_L259_T1.1550.99
148_S151_E1.1520.99
227_P237_L1.1520.99
303_C310_M1.1500.99
653_K661_L1.1490.99
521_A701_I1.1470.99
524_I571_F1.1470.99
237_L262_R1.1430.99
147_F150_N1.1400.99
287_I362_S1.1330.99
629_Q701_I1.1330.99
335_K339_Y1.1320.99
629_Q697_V1.1300.99
151_E154_F1.1290.99
527_E530_N1.1290.99
284_D359_E1.1280.99
653_K663_S1.1280.99
399_F419_N1.1270.99
573_I626_Q1.1190.98
227_P235_Q1.1120.98
409_F482_F1.1110.98
349_Q355_F1.1100.98
408_L416_I1.1040.98
387_E391_S1.1010.98
287_I299_N1.0980.98
538_F560_E1.0980.98
404_D479_E1.0920.98
288_I372_L1.0900.98
299_N303_C1.0890.98
598_L639_I1.0870.98
298_A313_L1.0860.98
713_S716_G1.0850.98
622_C627_L1.0810.98
630_V723_I1.0790.98
400_N420_P1.0780.98
649_F665_K1.0770.98
641_V687_K1.0720.98
529_R565_E1.0720.98
423_S430_H1.0710.98
295_I298_A1.0710.98
306_F348_F1.0700.98
528_I567_I1.0700.98
164_G180_S1.0660.98
357_E378_V1.0640.98
322_L346_L1.0600.98
299_N346_L1.0470.98
275_F297_K1.0420.98
182_C192_L1.0350.97
534_A538_F1.0320.97
537_G560_E1.0320.97
260_E263_S1.0320.97
280_E300_Q1.0320.97
540_Q558_T1.0290.97
535_L561_L1.0280.97
300_Q303_C1.0280.97
680_G721_F1.0220.97
286_I299_N1.0210.97
300_Q310_M1.0200.97
498_V502_K1.0130.97
307_E350_M1.0110.97
673_E714_E1.0110.97
597_L632_I1.0110.97
333_K362_S1.0100.97
158_F165_I1.0090.97
295_I299_N1.0070.97
570_E626_Q1.0060.97
522_A530_N1.0050.97
240_F255_M0.9980.97
712_E720_V0.9960.97
243_T252_M0.9940.97
409_F454_A0.9930.97
528_I564_I0.9920.97
586_H619_P0.9920.97
356_K379_S0.9900.97
163_D239_E0.9840.96
702_I709_I0.9840.96
480_F495_F0.9840.96
527_E560_E0.9830.96
535_L557_I0.9790.96
602_A639_I0.9760.96
529_R570_E0.9760.96
557_I561_L0.9760.96
295_I315_K0.9730.96
237_L258_I0.9730.96
275_F278_I0.9720.96
168_F174_F0.9710.96
712_E722_H0.9710.96
406_N419_N0.9690.96
556_V560_E0.9680.96
517_V530_N0.9640.96
500_E503_E0.9620.96
326_Q355_F0.9600.96
703_E708_E0.9590.96
522_A685_T0.9550.96
651_T665_K0.9520.96
164_G178_N0.9430.96
515_H519_E0.9400.95
642_M685_T0.9400.95
266_L270_K0.9370.95
685_T689_R0.9330.95
539_I558_T0.9320.95
518_G578_Q0.9310.95
671_M676_L0.9250.95
380_D383_R0.9240.95
626_Q701_I0.9240.95
659_H708_E0.9210.95
635_L650_V0.9210.95
220_G244_S0.9200.95
520_L525_A0.9180.95
710_M723_I0.9170.95
396_R400_N0.9160.95
710_M724_T0.9150.95
270_K274_R0.9100.95
215_A220_G0.9080.95
663_S722_H0.9030.94
230_L238_F0.9020.94
167_L175_I0.8970.94
288_I373_T0.8930.94
228_V236_K0.8910.94
636_K640_E0.8900.94
168_F251_Y0.8900.94
317_K320_D0.8900.94
278_I286_I0.8880.94
676_L713_S0.8850.94
641_V686_T0.8850.94
618_P654_A0.8800.94
723_I726_P0.8780.93
593_D628_K0.8780.93
608_Q647_N0.8780.93
334_R338_K0.8700.93
443_S467_P0.8700.93
405_G422_A0.8700.93
415_I422_A0.8690.93
418_A422_A0.8680.93
229_K235_Q0.8630.93
623_E626_Q0.8630.93
529_R564_I0.8610.93
528_I532_M0.8600.93
390_E394_K0.8600.93
358_L375_L0.8590.93
286_I372_L0.8590.93
666_D718_G0.8580.93
561_L565_E0.8580.93
482_F493_A0.8570.93
513_T521_A0.8560.93
363_K372_L0.8520.92
169_D172_G0.8510.92
283_M293_G0.8420.92
518_G528_I0.8420.92
527_E629_Q0.8420.92
486_I490_M0.8350.92
516_V682_P0.8330.92
316_R320_D0.8330.92
661_L710_M0.8320.92
408_L417_D0.8310.91
345_E381_R0.8310.91
478_L495_F0.8300.91
507_R511_S0.8290.91
177_A189_H0.8290.91
147_F151_E0.8290.91
523_G685_T0.8270.91
419_N499_T0.8260.91
399_F406_N0.8260.91
713_S717_K0.8250.91
308_L364_R0.8230.91
348_F356_K0.8210.91
325_S347_L0.8200.91
504_L507_R0.8190.91
267_Q270_K0.8190.91
335_K340_G0.8190.91
539_I543_K0.8180.91
693_L697_V0.8150.91
167_L252_M0.8150.91
285_A303_C0.8130.91
517_V646_G0.8110.90
482_F495_F0.8100.90
552_L556_V0.8070.90
650_V662_I0.8060.90
503_E506_E0.8060.90
238_F255_M0.8040.90
630_V705_H0.8020.90
174_F181_F0.7970.90
394_K417_D0.7950.90
405_G419_N0.7910.89
682_P696_M0.7900.89
588_T613_L0.7870.89
683_F696_M0.7840.89
521_A527_E0.7830.89
421_L424_H0.7830.89
527_E698_S0.7820.89
280_E299_N0.7810.89
264_M267_Q0.7790.89
318_L333_K0.7790.89
528_I531_P0.7780.89
185_F236_K0.7780.89
173_G194_H0.7780.89
675_K686_T0.7780.89
298_A306_F0.7770.88
545_S550_Y0.7770.88
308_L321_F0.7750.88
593_D624_P0.7740.88
419_N493_A0.7720.88
537_G561_L0.7720.88
306_F356_K0.7710.88
285_A306_F0.7710.88
215_A219_K0.7700.88
346_L362_S0.7700.88
172_G197_L0.7700.88
455_R459_F0.7690.88
322_L347_L0.7690.88
541_L553_Y0.7680.88
607_V642_M0.7670.88
531_P705_H0.7670.88
536_K539_I0.7670.88
415_I418_A0.7670.88
520_L641_V0.7650.88
185_F255_M0.7650.88
308_L350_M0.7640.88
660_V727_V0.7630.88
342_I362_S0.7630.88
283_M364_R0.7620.88
531_P697_V0.7620.88
305_I358_L0.7590.87
426_L468_F0.7590.87
523_G530_N0.7590.87
422_A426_L0.7590.87
516_V530_N0.7570.87
543_K554_F0.7550.87
174_F192_L0.7540.87
454_A482_F0.7530.87
681_E684_Y0.7520.87
522_A531_P0.7500.87
531_P570_E0.7500.87
521_A642_M0.7490.87
278_I288_I0.7490.87
535_L539_I0.7460.86
585_K590_I0.7430.86
445_Y467_P0.7420.86
186_E231_R0.7410.86
295_I313_L0.7400.86
514_L517_V0.7390.86
671_M713_S0.7390.86
289_W318_L0.7370.86
527_E564_I0.7360.86
408_L419_N0.7360.86
202_D205_S0.7330.85
686_T689_R0.7310.85
267_Q272_E0.7290.85
626_Q705_H0.7280.85
343_R361_T0.7280.85
587_V662_I0.7270.85
289_W373_T0.7250.85
299_N373_T0.7250.85
520_L572_L0.7240.85
573_I629_Q0.7230.85
684_Y687_K0.7210.84
274_R288_I0.7210.84
517_V642_M0.7200.84
640_E687_K0.7190.84
570_E697_V0.7190.84
576_K691_T0.7190.84
542_L557_I0.7190.84
634_I709_I0.7190.84
356_K377_N0.7180.84
279_F296_V0.7180.84
357_E382_K0.7180.84
531_P564_I0.7170.84
281_N286_I0.7170.84
477_K499_T0.7160.84
679_L711_V0.7150.84
285_A360_F0.7130.84
318_L346_L0.7120.84
189_H192_L0.7120.84
480_F493_A0.7120.84
669_I713_S0.7110.84
247_I250_F0.7100.84
288_I297_K0.7100.84
631_F664_L0.7070.83
357_E379_S0.7070.83
572_L575_A0.7060.83
536_K558_T0.7040.83
324_D327_Q0.7040.83
568_I629_Q0.7020.83
266_L269_F0.7010.83
225_E261_K0.7000.83
539_I561_L0.6980.83
671_M695_L0.6960.82
417_D430_H0.6950.82
530_N537_G0.6950.82
530_N565_E0.6950.82
524_I530_N0.6950.82
228_V237_L0.6940.82
613_L652_I0.6920.82
570_E641_V0.6910.82
635_L648_I0.6910.82
319_C327_Q0.6910.82
288_I293_G0.6860.81
525_A641_V0.6860.81
157_L167_L0.6860.81
187_I238_F0.6840.81
534_A557_I0.6840.81
516_V527_E0.6830.81
527_E683_F0.6820.81
214_K218_R0.6810.81
483_K492_L0.6800.81
213_W217_N0.6800.81
523_G529_R0.6790.81
287_I293_G0.6790.81
167_L176_D0.6790.81
322_L348_F0.6780.81
573_I577_P0.6770.81
477_K498_V0.6770.81
523_G641_V0.6770.81
529_R569_T0.6750.80
345_E359_E0.6740.80
640_E686_T0.6740.80
179_L189_H0.6720.80
598_L632_I0.6720.80
166_V177_A0.6710.80
477_K480_F0.6710.80
289_W295_I0.6700.80
393_L397_K0.6700.80
226_L240_F0.6690.80
538_F557_I0.6690.80
525_A529_R0.6690.80
521_A629_Q0.6680.80
572_L623_E0.6680.80
237_L256_R0.6670.80
409_F438_L0.6650.79
612_D653_K0.6640.79
517_V522_A0.6640.79
177_A185_F0.6620.79
164_G240_F0.6620.79
278_I283_M0.6620.79
178_N181_F0.6600.79
466_I480_F0.6590.79
525_A531_P0.6590.79
587_V660_V0.6580.79
317_K321_F0.6560.78
465_E479_E0.6560.78
522_A528_I0.6540.78
514_L518_G0.6530.78
607_V641_V0.6530.78
642_M687_K0.6520.78
196_S200_F0.6520.78
418_A430_H0.6510.78
530_N564_I0.6510.78
524_I685_T0.6510.78
634_I702_I0.6500.78
520_L531_P0.6490.78
527_E697_V0.6490.78
516_V529_R0.6490.78
469_L475_N0.6490.78
682_P700_K0.6480.78
418_A433_I0.6480.78
295_I373_T0.6470.78
297_K300_Q0.6470.78
580_I705_H0.6460.77
148_S152_Q0.6440.77
553_Y560_E0.6430.77
278_I282_A0.6410.77
528_I698_S0.6410.77
172_G178_N0.6410.77
513_T517_V0.6400.77
529_R642_M0.6390.77
185_F200_F0.6380.77
225_E239_E0.6370.76
696_M700_K0.6370.76
523_G687_K0.6370.76
419_N423_S0.6370.76
545_S553_Y0.6370.76
517_V520_L0.6360.76
409_F493_A0.6360.76
564_I577_P0.6360.76
287_I298_A0.6360.76
408_L492_L0.6350.76
348_F358_L0.6350.76
308_L313_L0.6350.76
594_T598_L0.6340.76
302_A375_L0.6340.76
236_K257_D0.6330.76
527_E533_T0.6320.76
569_T573_I0.6310.76
530_N534_A0.6290.76
477_K502_K0.6290.76
181_F198_Y0.6270.75
518_G685_T0.6270.75
303_C313_L0.6270.75
563_R576_K0.6270.75
155_K158_F0.6260.75
150_N155_K0.6260.75
181_F255_M0.6260.75
590_I627_L0.6250.75
386_K390_E0.6240.75
520_L564_I0.6230.75
516_V522_A0.6220.75
408_L493_A0.6220.75
281_N288_I0.6220.75
523_G682_P0.6200.74
533_T538_F0.6200.74
652_I662_I0.6200.74
279_F372_L0.6200.74
295_I362_S0.6190.74
185_F201_I0.6180.74
415_I437_S0.6180.74
159_D176_D0.6180.74
528_I568_I0.6170.74
707_G726_P0.6160.74
457_I460_D0.6160.74
288_I296_V0.6160.74
463_D479_E0.6150.74
389_R392_E0.6140.74
521_A573_I0.6140.74
595_I609_M0.6130.74
169_D175_I0.6130.74
226_L238_F0.6130.74
518_G522_A0.6120.74
476_R499_T0.6110.73
444_A447_I0.6110.73
279_F287_I0.6100.73
176_D250_F0.6090.73
228_V255_M0.6090.73
518_G687_K0.6080.73
328_K331_I0.6080.73
678_R684_Y0.6070.73
236_K251_Y0.6070.73
512_D527_E0.6070.73
536_K565_E0.6070.73
580_I623_E0.6070.73
165_I252_M0.6070.73
428_L476_R0.6070.73
627_L705_H0.6060.73
698_S723_I0.6060.73
181_F228_V0.6050.73
242_I253_S0.6040.73
158_F167_L0.6030.72
594_T635_L0.6020.72
647_N667_E0.6010.72
521_A530_N0.6010.72
223_K241_T0.6000.72
523_G564_I0.6000.72
675_K684_Y0.6000.72
647_N665_K0.5990.72
521_A578_Q0.5990.72
538_F686_T0.5990.72
302_A359_E0.5980.72
185_F228_V0.5980.72
649_F667_E0.5980.72
167_L245_N0.5980.72
696_M721_F0.5980.72
591_M662_I0.5970.72
534_A556_V0.5960.72
305_I375_L0.5950.71
288_I291_N0.5940.71
299_N360_F0.5930.71
293_G299_N0.5930.71
572_L576_K0.5930.71
542_L556_V0.5920.71
528_I622_C0.5920.71
438_L454_A0.5910.71
520_L524_I0.5910.71
680_G711_V0.5910.71
522_A646_G0.5880.71
161_A252_M0.5870.70
360_F373_T0.5860.70
527_E685_T0.5860.70
631_F635_L0.5850.70
477_K484_R0.5840.70
517_V685_T0.5840.70
201_I250_F0.5830.70
521_A697_V0.5820.70
531_P629_Q0.5820.70
517_V529_R0.5810.70
521_A524_I0.5810.70
538_F556_V0.5810.70
395_F417_D0.5800.70
543_K551_A0.5800.70
534_A537_G0.5790.69
414_R437_S0.5790.69
517_V573_I0.5780.69
228_V238_F0.5780.69
163_D254_I0.5770.69
236_K242_I0.5770.69
443_S475_N0.5760.69
528_I705_H0.5750.69
582_Y705_H0.5750.69
531_P568_I0.5740.69
322_L326_Q0.5720.68
181_F242_I0.5720.68
275_F284_D0.5710.68
517_V687_K0.5710.68
281_N299_N0.5690.68
574_L700_K0.5690.68
567_I572_L0.5690.68
572_L691_T0.5690.68
590_I594_T0.5680.68
405_G480_F0.5680.68
202_D228_V0.5680.68
517_V565_E0.5660.68
302_A373_T0.5650.68
182_C253_S0.5650.68
242_I250_F0.5630.67
197_L202_D0.5630.67
662_I725_L0.5630.67
577_P641_V0.5620.67
514_L529_R0.5620.67
629_Q633_N0.5620.67
346_L358_L0.5610.67
558_T562_K0.5610.67
539_I554_F0.5600.67
517_V640_E0.5590.67
275_F286_I0.5590.67
557_I563_R0.5590.67
164_G182_C0.5570.66
520_L529_R0.5560.66
283_M288_I0.5560.66
427_G471_S0.5550.66
226_L242_I0.5550.66
533_T560_E0.5550.66
278_I281_N0.5540.66
636_K697_V0.5540.66
169_D250_F0.5540.66
187_I230_L0.5540.66
406_N417_D0.5530.66
523_G642_M0.5520.66
282_A285_A0.5500.65
163_D241_T0.5500.65
675_K678_R0.5500.65
570_E629_Q0.5490.65
150_N154_F0.5480.65
423_S429_S0.5470.65
286_I297_K0.5470.65
166_V255_M0.5470.65
597_L641_V0.5470.65
159_D178_N0.5460.65
518_G529_R0.5460.65
423_S433_I0.5460.65
384_M387_E0.5460.65
405_G482_F0.5450.65
574_L691_T0.5450.65
683_F690_G0.5450.65
161_A254_I0.5440.65
285_A301_S0.5440.65
626_Q687_K0.5440.65
443_S447_I0.5440.65
302_A355_F0.5430.65
524_I560_E0.5430.65
636_K641_V0.5420.64
517_V523_G0.5420.64
406_N413_Y0.5410.64
326_Q346_L0.5410.64
209_F212_I0.5400.64
525_A572_L0.5400.64
387_E390_E0.5390.64
637_N694_G0.5380.64
634_I723_I0.5380.64
287_I301_S0.5380.64
529_R538_F0.5370.64
185_F252_M0.5360.64
309_P351_G0.5360.64
530_N632_I0.5350.63
201_I228_V0.5350.63
530_N533_T0.5350.63
422_A482_F0.5350.63
518_G523_G0.5350.63
279_F285_A0.5350.63
167_L178_N0.5330.63
524_I578_Q0.5330.63
287_I360_F0.5320.63
273_E277_E0.5310.63
225_E258_I0.5310.63
678_R681_E0.5300.63
438_L482_F0.5300.63
625_N628_K0.5290.63
413_Y419_N0.5290.63
597_L682_P0.5290.63
529_R572_L0.5290.63
523_G527_E0.5280.62
525_A697_V0.5280.62
236_K259_T0.5260.62
215_A221_K0.5260.62
538_F628_K0.5260.62
345_E378_V0.5250.62
521_A685_T0.5240.62
405_G492_L0.5240.62
333_K346_L0.5240.62
153_L176_D0.5230.62
327_Q362_S0.5230.62
405_G423_S0.5230.62
274_R297_K0.5230.62
521_A533_T0.5220.61
288_I295_I0.5220.61
533_T564_I0.5210.61
428_L433_I0.5210.61
177_A180_S0.5200.61
641_V669_I0.5200.61
517_V564_I0.5190.61
599_N603_N0.5180.61
399_F408_L0.5180.61
197_L242_I0.5170.61
529_R537_G0.5160.61
594_T628_K0.5160.61
597_L642_M0.5150.60
346_L357_E0.5150.60
520_L571_F0.5150.60
237_L243_T0.5150.60
279_F376_R0.5150.60
182_C188_N0.5140.60
516_V523_G0.5140.60
201_I226_L0.5140.60
269_F273_E0.5140.60
520_L528_I0.5140.60
366_I370_Q0.5140.60
403_M496_K0.5130.60
407_V482_F0.5120.60
208_D211_N0.5120.60
277_E281_N0.5110.60
216_L244_S0.5090.60
288_I362_S0.5090.60
231_R236_K0.5080.59
438_L493_A0.5080.59
457_I461_E0.5080.59
275_F288_I0.5080.59
364_R372_L0.5070.59
518_G682_P0.5070.59
419_N425_I0.5060.59
284_D301_S0.5050.59
642_M701_I0.5050.59
287_I372_L0.5040.59
520_L640_E0.5040.59
307_E352_N0.5040.59
670_G718_G0.5040.59
642_M686_T0.5030.59
152_Q155_K0.5030.59
521_A577_P0.5030.59
527_E626_Q0.5030.59
548_G551_A0.5030.59
525_A640_E0.5020.59
674_D677_K0.5020.59
406_N492_L0.5020.59
520_L626_Q0.5020.59
224_G228_V0.5020.59
295_I321_F0.5020.59
517_V525_A0.5010.58
294_R315_K0.5000.58
537_G564_I0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4gczA 2 0.4824 100 0.603 Contact Map
3a0rA 2 0.4404 100 0.613 Contact Map
4i5sA 2 0.5149 100 0.625 Contact Map
4r3aA 1 0.4187 100 0.679 Contact Map
4q20A 2 0.2995 100 0.719 Contact Map
3d36A 2 0.2954 100 0.72 Contact Map
4mpcA 2 0.4133 100 0.722 Contact Map
2q8gA 2 0.4079 100 0.724 Contact Map
4e01A 3 0.3889 100 0.725 Contact Map
2c2aA 2 0.3089 100 0.725 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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