KINE - BACSU - GREMLIN Contacts

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KINE - Sporulation kinase E

UniProt:	O31661	Sequences: METLGVQTNSELREELNRLKEENARLKKELNQHQVIVNNTLDAIFICDNEMRIVQANEATERMLQVDSEDLKKRSVLDFLFSIPKDELNLSVKKFFKKGFLWKEVPIRLDCGATKYIEFLAKRGIGEDFFFVVMRDISSKKILEREFSMNEQLFKDLFDRAVDGIVLFDKDGGFIDANLSFCKSFEINHNELSHLSLYEFIDSGSRKDFDNIWKALNRKGKAKGELPVKLRSGVQKLFEFTITSNIISGFYMSIMRDITEKRSMELQLFKSEERFREIFENAMDAIIIWSNDGRIVKANQSACKIFELPMNLLLKRKLCDFLVDSQQKYSITKRKYAKYGEIREELLFQMGNGQFKELEFTSKRTILENQHLTILRNVSDRKRMEKELRESELKFRKVFNGSMDGNVLFDNQYRIIDANPLASHILGLSHEEIKQHSLLDIISAYEIENLASPARQINFDEMDNEIPFLLSSGDNRKLEFSFKRNIIQNMNLAIFKDVTERKELEERLRKSDTLHVVGELAAGIAHEIRNPMTALKGFIQLLKGSVEGDYALYFNVITSELKRIESIITEFLILAKPQAIMYEEKHVTQIMRDTIDLLNAQANLSNVQMQLDLIDDIPPIYCEPNQLKQVFINILKNAIEVMPDGGNIFVTIKALDQDHVLISLKDEGIGMTEDKLKRLGEPFYTTKERGTGLGLMVSYKIIEEHQGEIMVESEEGKGTVFHITLPVRQNAEERRNDE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	738 (582)
Sequences:	3102 (2722)
Seq/√Len:	112.8

BACSU - KINE KINA
HALSA - O51970 Q9HQ16

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
284_D	376_R	5.389	1.00
539_I	557_I	5.279	1.00
163_D	256_R	5.062	1.00
404_D	496_K	4.849	1.00
392_E	396_R	3.860	1.00
714_E	717_K	3.515	1.00
287_I	373_T	3.500	1.00
285_A	305_I	3.484	1.00
710_M	722_H	3.411	1.00
711_V	721_F	3.236	1.00
326_Q	347_L	3.207	1.00
187_I	231_R	3.150	1.00
272_E	276_R	3.125	1.00
308_L	351_G	3.079	1.00
381_R	385_E	2.954	1.00
345_E	382_K	2.925	1.00
262_R	265_E	2.861	1.00
312_L	351_G	2.841	1.00
359_E	376_R	2.756	1.00
279_F	297_K	2.753	1.00
662_I	723_I	2.748	1.00
239_E	256_R	2.709	1.00
367_L	370_Q	2.694	1.00
367_L	371_H	2.679	1.00
225_E	262_R	2.652	1.00
641_V	685_T	2.633	1.00
665_K	720_V	2.624	1.00
502_K	505_E	2.591	1.00
407_V	493_A	2.531	1.00
399_F	417_D	2.506	1.00
699_Y	703_E	2.475	1.00
166_V	174_F	2.456	1.00
158_F	176_D	2.447	1.00
405_G	425_I	2.409	1.00
323_V	347_L	2.384	1.00
191_E	231_R	2.378	1.00
230_L	234_V	2.360	1.00
161_A	165_I	2.343	1.00
405_G	495_F	2.305	1.00
661_L	722_H	2.291	1.00
479_E	496_K	2.286	1.00
642_M	667_E	2.276	1.00
676_L	711_V	2.272	1.00
261_K	265_E	2.268	1.00
428_L	471_S	2.258	1.00
301_S	304_K	2.257	1.00
285_A	375_L	2.231	1.00
487_I	490_M	2.229	1.00
672_T	675_K	2.224	1.00
164_G	255_M	2.223	1.00
350_M	354_Q	2.217	1.00
698_S	709_I	2.197	1.00
583_E	624_P	2.180	1.00
151_E	155_K	2.177	1.00
382_K	385_E	2.166	1.00
323_V	326_Q	2.118	1.00
671_M	675_K	2.108	1.00
505_E	509_R	2.035	1.00
164_G	184_S	2.002	1.00
159_D	179_L	1.999	1.00
465_E	502_K	1.995	1.00
275_F	279_F	1.992	1.00
169_D	173_G	1.978	1.00
630_V	702_I	1.967	1.00
177_A	181_F	1.956	1.00
287_I	295_I	1.926	1.00
276_R	280_E	1.879	1.00
392_E	395_F	1.865	1.00
391_S	394_K	1.862	1.00
432_E	471_S	1.849	1.00
501_R	505_E	1.847	1.00
230_L	236_K	1.842	1.00
223_K	239_E	1.827	1.00
166_V	253_S	1.822	1.00
182_C	189_H	1.814	1.00
179_L	183_K	1.807	1.00
164_G	181_F	1.801	1.00
585_K	622_C	1.793	1.00
536_K	561_L	1.789	1.00
282_A	286_I	1.780	1.00
522_A	527_E	1.773	1.00
630_V	698_S	1.771	1.00
177_A	182_C	1.746	1.00
508_L	511_S	1.744	1.00
565_E	569_T	1.738	1.00
537_G	541_L	1.732	1.00
436_H	440_D	1.710	1.00
630_V	701_I	1.696	1.00
470_L	474_D	1.693	1.00
343_R	359_E	1.680	1.00
622_C	705_H	1.675	1.00
402_S	406_N	1.662	1.00
711_V	719_T	1.659	1.00
702_I	723_I	1.658	1.00
385_E	389_R	1.651	1.00
347_L	357_E	1.647	1.00
546_V	550_Y	1.643	1.00
272_E	275_F	1.637	1.00
642_M	648_I	1.637	1.00
347_L	355_F	1.633	1.00
407_V	415_I	1.622	1.00
640_E	685_T	1.620	1.00
285_A	302_A	1.620	1.00
258_I	262_R	1.616	1.00
504_L	508_L	1.609	1.00
288_I	299_N	1.601	1.00
391_S	395_F	1.599	1.00
487_I	491_N	1.592	1.00
267_Q	271_S	1.584	1.00
651_T	663_S	1.572	1.00
302_A	306_F	1.570	1.00
346_L	360_F	1.558	1.00
309_P	312_L	1.557	1.00
671_M	679_L	1.555	1.00
527_E	531_P	1.552	1.00
175_I	250_F	1.552	1.00
187_I	191_E	1.545	1.00
410_D	414_R	1.537	1.00
350_M	356_K	1.531	1.00
610_Q	647_N	1.525	1.00
586_H	589_Q	1.520	1.00
612_D	649_F	1.519	1.00
395_F	398_V	1.516	1.00
418_A	423_S	1.514	1.00
154_F	158_F	1.513	1.00
584_E	621_Y	1.502	1.00
395_F	399_F	1.494	1.00
285_A	299_N	1.493	1.00
701_I	705_H	1.481	1.00
181_F	185_F	1.471	1.00
443_S	446_E	1.469	1.00
271_S	274_R	1.465	1.00
298_A	303_C	1.464	1.00
543_K	558_T	1.457	1.00
168_F	253_S	1.454	1.00
308_L	312_L	1.451	1.00
242_I	251_Y	1.447	1.00
517_V	521_A	1.435	1.00
547_E	550_Y	1.435	1.00
479_E	501_R	1.428	1.00
279_F	299_N	1.423	1.00
188_N	191_E	1.422	1.00
180_S	183_K	1.415	1.00
166_V	181_F	1.414	1.00
680_G	709_I	1.407	1.00
289_W	333_K	1.401	1.00
323_V	355_F	1.400	1.00
642_M	646_G	1.395	1.00
359_E	381_R	1.393	1.00
506_E	509_R	1.382	1.00
631_F	662_I	1.379	1.00
672_T	715_E	1.375	1.00
661_L	724_T	1.370	1.00
446_E	467_P	1.366	1.00
634_I	664_L	1.364	1.00
602_A	648_I	1.359	1.00
456_Q	461_E	1.359	1.00
386_K	389_R	1.358	1.00
503_E	507_R	1.353	1.00
195_L	199_E	1.351	1.00
419_N	497_D	1.350	1.00
673_E	676_L	1.346	1.00
388_L	391_S	1.345	1.00
239_E	261_K	1.344	1.00
429_S	432_E	1.338	1.00
646_G	667_E	1.335	1.00
244_S	250_F	1.331	1.00
542_L	554_F	1.331	1.00
378_V	382_K	1.328	1.00
534_A	560_E	1.322	1.00
420_P	423_S	1.319	1.00
279_F	286_I	1.318	1.00
420_P	424_H	1.312	1.00
168_F	242_I	1.310	1.00
428_L	432_E	1.308	1.00
588_T	652_I	1.294	0.99
525_A	530_N	1.292	0.99
538_F	553_Y	1.292	0.99
507_R	510_K	1.288	0.99
470_L	476_R	1.287	0.99
300_Q	304_K	1.287	0.99
527_E	567_I	1.284	0.99
659_H	724_T	1.283	0.99
150_N	153_L	1.283	0.99
290_S	294_R	1.279	0.99
265_E	269_F	1.278	0.99
543_K	555_N	1.277	0.99
167_L	250_F	1.276	0.99
289_W	293_G	1.271	0.99
679_L	721_F	1.264	0.99
391_S	396_R	1.260	0.99
155_K	159_D	1.260	0.99
154_F	157_L	1.257	0.99
542_L	550_Y	1.246	0.99
196_S	199_E	1.241	0.99
271_S	275_F	1.239	0.99
419_N	422_A	1.239	0.99
287_I	302_A	1.235	0.99
268_L	271_S	1.232	0.99
612_D	651_T	1.231	0.99
591_M	650_V	1.230	0.99
663_S	720_V	1.228	0.99
407_V	422_A	1.225	0.99
298_A	302_A	1.221	0.99
467_P	477_K	1.214	0.99
702_I	707_G	1.214	0.99
215_A	218_R	1.213	0.99
289_W	362_S	1.213	0.99
177_A	192_L	1.210	0.99
283_M	299_N	1.209	0.99
666_D	670_G	1.208	0.99
269_F	272_E	1.206	0.99
176_D	189_H	1.204	0.99
299_N	302_A	1.204	0.99
713_S	719_T	1.203	0.99
360_F	375_L	1.203	0.99
168_F	197_L	1.201	0.99
271_S	276_R	1.197	0.99
467_P	475_N	1.191	0.99
205_S	227_P	1.184	0.99
598_L	635_L	1.182	0.99
173_G	196_S	1.180	0.99
179_L	182_C	1.174	0.99
610_Q	649_F	1.171	0.99
336_Y	364_R	1.165	0.99
626_Q	629_Q	1.161	0.99
476_R	497_D	1.158	0.99
237_L	259_T	1.155	0.99
148_S	151_E	1.152	0.99
227_P	237_L	1.152	0.99
303_C	310_M	1.150	0.99
653_K	661_L	1.149	0.99
521_A	701_I	1.147	0.99
524_I	571_F	1.147	0.99
237_L	262_R	1.143	0.99
147_F	150_N	1.140	0.99
287_I	362_S	1.133	0.99
629_Q	701_I	1.133	0.99
335_K	339_Y	1.132	0.99
629_Q	697_V	1.130	0.99
151_E	154_F	1.129	0.99
527_E	530_N	1.129	0.99
284_D	359_E	1.128	0.99
653_K	663_S	1.128	0.99
399_F	419_N	1.127	0.99
573_I	626_Q	1.119	0.98
227_P	235_Q	1.112	0.98
409_F	482_F	1.111	0.98
349_Q	355_F	1.110	0.98
408_L	416_I	1.104	0.98
387_E	391_S	1.101	0.98
287_I	299_N	1.098	0.98
538_F	560_E	1.098	0.98
404_D	479_E	1.092	0.98
288_I	372_L	1.090	0.98
299_N	303_C	1.089	0.98
598_L	639_I	1.087	0.98
298_A	313_L	1.086	0.98
713_S	716_G	1.085	0.98
622_C	627_L	1.081	0.98
630_V	723_I	1.079	0.98
400_N	420_P	1.078	0.98
649_F	665_K	1.077	0.98
641_V	687_K	1.072	0.98
529_R	565_E	1.072	0.98
423_S	430_H	1.071	0.98
295_I	298_A	1.071	0.98
306_F	348_F	1.070	0.98
528_I	567_I	1.070	0.98
164_G	180_S	1.066	0.98
357_E	378_V	1.064	0.98
322_L	346_L	1.060	0.98
299_N	346_L	1.047	0.98
275_F	297_K	1.042	0.98
182_C	192_L	1.035	0.97
534_A	538_F	1.032	0.97
537_G	560_E	1.032	0.97
260_E	263_S	1.032	0.97
280_E	300_Q	1.032	0.97
540_Q	558_T	1.029	0.97
535_L	561_L	1.028	0.97
300_Q	303_C	1.028	0.97
680_G	721_F	1.022	0.97
286_I	299_N	1.021	0.97
300_Q	310_M	1.020	0.97
498_V	502_K	1.013	0.97
307_E	350_M	1.011	0.97
673_E	714_E	1.011	0.97
597_L	632_I	1.011	0.97
333_K	362_S	1.010	0.97
158_F	165_I	1.009	0.97
295_I	299_N	1.007	0.97
570_E	626_Q	1.006	0.97
522_A	530_N	1.005	0.97
240_F	255_M	0.998	0.97
712_E	720_V	0.996	0.97
243_T	252_M	0.994	0.97
409_F	454_A	0.993	0.97
528_I	564_I	0.992	0.97
586_H	619_P	0.992	0.97
356_K	379_S	0.990	0.97
163_D	239_E	0.984	0.96
702_I	709_I	0.984	0.96
480_F	495_F	0.984	0.96
527_E	560_E	0.983	0.96
535_L	557_I	0.979	0.96
602_A	639_I	0.976	0.96
529_R	570_E	0.976	0.96
557_I	561_L	0.976	0.96
295_I	315_K	0.973	0.96
237_L	258_I	0.973	0.96
275_F	278_I	0.972	0.96
168_F	174_F	0.971	0.96
712_E	722_H	0.971	0.96
406_N	419_N	0.969	0.96
556_V	560_E	0.968	0.96
517_V	530_N	0.964	0.96
500_E	503_E	0.962	0.96
326_Q	355_F	0.960	0.96
703_E	708_E	0.959	0.96
522_A	685_T	0.955	0.96
651_T	665_K	0.952	0.96
164_G	178_N	0.943	0.96
515_H	519_E	0.940	0.95
642_M	685_T	0.940	0.95
266_L	270_K	0.937	0.95
685_T	689_R	0.933	0.95
539_I	558_T	0.932	0.95
518_G	578_Q	0.931	0.95
671_M	676_L	0.925	0.95
380_D	383_R	0.924	0.95
626_Q	701_I	0.924	0.95
659_H	708_E	0.921	0.95
635_L	650_V	0.921	0.95
220_G	244_S	0.920	0.95
520_L	525_A	0.918	0.95
710_M	723_I	0.917	0.95
396_R	400_N	0.916	0.95
710_M	724_T	0.915	0.95
270_K	274_R	0.910	0.95
215_A	220_G	0.908	0.95
663_S	722_H	0.903	0.94
230_L	238_F	0.902	0.94
167_L	175_I	0.897	0.94
288_I	373_T	0.893	0.94
228_V	236_K	0.891	0.94
636_K	640_E	0.890	0.94
168_F	251_Y	0.890	0.94
317_K	320_D	0.890	0.94
278_I	286_I	0.888	0.94
676_L	713_S	0.885	0.94
641_V	686_T	0.885	0.94
618_P	654_A	0.880	0.94
723_I	726_P	0.878	0.93
593_D	628_K	0.878	0.93
608_Q	647_N	0.878	0.93
334_R	338_K	0.870	0.93
443_S	467_P	0.870	0.93
405_G	422_A	0.870	0.93
415_I	422_A	0.869	0.93
418_A	422_A	0.868	0.93
229_K	235_Q	0.863	0.93
623_E	626_Q	0.863	0.93
529_R	564_I	0.861	0.93
528_I	532_M	0.860	0.93
390_E	394_K	0.860	0.93
358_L	375_L	0.859	0.93
286_I	372_L	0.859	0.93
666_D	718_G	0.858	0.93
561_L	565_E	0.858	0.93
482_F	493_A	0.857	0.93
513_T	521_A	0.856	0.93
363_K	372_L	0.852	0.92
169_D	172_G	0.851	0.92
283_M	293_G	0.842	0.92
518_G	528_I	0.842	0.92
527_E	629_Q	0.842	0.92
486_I	490_M	0.835	0.92
516_V	682_P	0.833	0.92
316_R	320_D	0.833	0.92
661_L	710_M	0.832	0.92
408_L	417_D	0.831	0.91
345_E	381_R	0.831	0.91
478_L	495_F	0.830	0.91
507_R	511_S	0.829	0.91
177_A	189_H	0.829	0.91
147_F	151_E	0.829	0.91
523_G	685_T	0.827	0.91
419_N	499_T	0.826	0.91
399_F	406_N	0.826	0.91
713_S	717_K	0.825	0.91
308_L	364_R	0.823	0.91
348_F	356_K	0.821	0.91
325_S	347_L	0.820	0.91
504_L	507_R	0.819	0.91
267_Q	270_K	0.819	0.91
335_K	340_G	0.819	0.91
539_I	543_K	0.818	0.91
693_L	697_V	0.815	0.91
167_L	252_M	0.815	0.91
285_A	303_C	0.813	0.91
517_V	646_G	0.811	0.90
482_F	495_F	0.810	0.90
552_L	556_V	0.807	0.90
650_V	662_I	0.806	0.90
503_E	506_E	0.806	0.90
238_F	255_M	0.804	0.90
630_V	705_H	0.802	0.90
174_F	181_F	0.797	0.90
394_K	417_D	0.795	0.90
405_G	419_N	0.791	0.89
682_P	696_M	0.790	0.89
588_T	613_L	0.787	0.89
683_F	696_M	0.784	0.89
521_A	527_E	0.783	0.89
421_L	424_H	0.783	0.89
527_E	698_S	0.782	0.89
280_E	299_N	0.781	0.89
264_M	267_Q	0.779	0.89
318_L	333_K	0.779	0.89
528_I	531_P	0.778	0.89
185_F	236_K	0.778	0.89
173_G	194_H	0.778	0.89
675_K	686_T	0.778	0.89
298_A	306_F	0.777	0.88
545_S	550_Y	0.777	0.88
308_L	321_F	0.775	0.88
593_D	624_P	0.774	0.88
419_N	493_A	0.772	0.88
537_G	561_L	0.772	0.88
306_F	356_K	0.771	0.88
285_A	306_F	0.771	0.88
215_A	219_K	0.770	0.88
346_L	362_S	0.770	0.88
172_G	197_L	0.770	0.88
455_R	459_F	0.769	0.88
322_L	347_L	0.769	0.88
541_L	553_Y	0.768	0.88
607_V	642_M	0.767	0.88
531_P	705_H	0.767	0.88
536_K	539_I	0.767	0.88
415_I	418_A	0.767	0.88
520_L	641_V	0.765	0.88
185_F	255_M	0.765	0.88
308_L	350_M	0.764	0.88
660_V	727_V	0.763	0.88
342_I	362_S	0.763	0.88
283_M	364_R	0.762	0.88
531_P	697_V	0.762	0.88
305_I	358_L	0.759	0.87
426_L	468_F	0.759	0.87
523_G	530_N	0.759	0.87
422_A	426_L	0.759	0.87
516_V	530_N	0.757	0.87
543_K	554_F	0.755	0.87
174_F	192_L	0.754	0.87
454_A	482_F	0.753	0.87
681_E	684_Y	0.752	0.87
522_A	531_P	0.750	0.87
531_P	570_E	0.750	0.87
521_A	642_M	0.749	0.87
278_I	288_I	0.749	0.87
535_L	539_I	0.746	0.86
585_K	590_I	0.743	0.86
445_Y	467_P	0.742	0.86
186_E	231_R	0.741	0.86
295_I	313_L	0.740	0.86
514_L	517_V	0.739	0.86
671_M	713_S	0.739	0.86
289_W	318_L	0.737	0.86
527_E	564_I	0.736	0.86
408_L	419_N	0.736	0.86
202_D	205_S	0.733	0.85
686_T	689_R	0.731	0.85
267_Q	272_E	0.729	0.85
626_Q	705_H	0.728	0.85
343_R	361_T	0.728	0.85
587_V	662_I	0.727	0.85
289_W	373_T	0.725	0.85
299_N	373_T	0.725	0.85
520_L	572_L	0.724	0.85
573_I	629_Q	0.723	0.85
684_Y	687_K	0.721	0.84
274_R	288_I	0.721	0.84
517_V	642_M	0.720	0.84
640_E	687_K	0.719	0.84
570_E	697_V	0.719	0.84
576_K	691_T	0.719	0.84
542_L	557_I	0.719	0.84
634_I	709_I	0.719	0.84
356_K	377_N	0.718	0.84
279_F	296_V	0.718	0.84
357_E	382_K	0.718	0.84
531_P	564_I	0.717	0.84
281_N	286_I	0.717	0.84
477_K	499_T	0.716	0.84
679_L	711_V	0.715	0.84
285_A	360_F	0.713	0.84
318_L	346_L	0.712	0.84
189_H	192_L	0.712	0.84
480_F	493_A	0.712	0.84
669_I	713_S	0.711	0.84
247_I	250_F	0.710	0.84
288_I	297_K	0.710	0.84
631_F	664_L	0.707	0.83
357_E	379_S	0.707	0.83
572_L	575_A	0.706	0.83
536_K	558_T	0.704	0.83
324_D	327_Q	0.704	0.83
568_I	629_Q	0.702	0.83
266_L	269_F	0.701	0.83
225_E	261_K	0.700	0.83
539_I	561_L	0.698	0.83
671_M	695_L	0.696	0.82
417_D	430_H	0.695	0.82
530_N	537_G	0.695	0.82
530_N	565_E	0.695	0.82
524_I	530_N	0.695	0.82
228_V	237_L	0.694	0.82
613_L	652_I	0.692	0.82
570_E	641_V	0.691	0.82
635_L	648_I	0.691	0.82
319_C	327_Q	0.691	0.82
288_I	293_G	0.686	0.81
525_A	641_V	0.686	0.81
157_L	167_L	0.686	0.81
187_I	238_F	0.684	0.81
534_A	557_I	0.684	0.81
516_V	527_E	0.683	0.81
527_E	683_F	0.682	0.81
214_K	218_R	0.681	0.81
483_K	492_L	0.680	0.81
213_W	217_N	0.680	0.81
523_G	529_R	0.679	0.81
287_I	293_G	0.679	0.81
167_L	176_D	0.679	0.81
322_L	348_F	0.678	0.81
573_I	577_P	0.677	0.81
477_K	498_V	0.677	0.81
523_G	641_V	0.677	0.81
529_R	569_T	0.675	0.80
345_E	359_E	0.674	0.80
640_E	686_T	0.674	0.80
179_L	189_H	0.672	0.80
598_L	632_I	0.672	0.80
166_V	177_A	0.671	0.80
477_K	480_F	0.671	0.80
289_W	295_I	0.670	0.80
393_L	397_K	0.670	0.80
226_L	240_F	0.669	0.80
538_F	557_I	0.669	0.80
525_A	529_R	0.669	0.80
521_A	629_Q	0.668	0.80
572_L	623_E	0.668	0.80
237_L	256_R	0.667	0.80
409_F	438_L	0.665	0.79
612_D	653_K	0.664	0.79
517_V	522_A	0.664	0.79
177_A	185_F	0.662	0.79
164_G	240_F	0.662	0.79
278_I	283_M	0.662	0.79
178_N	181_F	0.660	0.79
466_I	480_F	0.659	0.79
525_A	531_P	0.659	0.79
587_V	660_V	0.658	0.79
317_K	321_F	0.656	0.78
465_E	479_E	0.656	0.78
522_A	528_I	0.654	0.78
514_L	518_G	0.653	0.78
607_V	641_V	0.653	0.78
642_M	687_K	0.652	0.78
196_S	200_F	0.652	0.78
418_A	430_H	0.651	0.78
530_N	564_I	0.651	0.78
524_I	685_T	0.651	0.78
634_I	702_I	0.650	0.78
520_L	531_P	0.649	0.78
527_E	697_V	0.649	0.78
516_V	529_R	0.649	0.78
469_L	475_N	0.649	0.78
682_P	700_K	0.648	0.78
418_A	433_I	0.648	0.78
295_I	373_T	0.647	0.78
297_K	300_Q	0.647	0.78
580_I	705_H	0.646	0.77
148_S	152_Q	0.644	0.77
553_Y	560_E	0.643	0.77
278_I	282_A	0.641	0.77
528_I	698_S	0.641	0.77
172_G	178_N	0.641	0.77
513_T	517_V	0.640	0.77
529_R	642_M	0.639	0.77
185_F	200_F	0.638	0.77
225_E	239_E	0.637	0.76
696_M	700_K	0.637	0.76
523_G	687_K	0.637	0.76
419_N	423_S	0.637	0.76
545_S	553_Y	0.637	0.76
517_V	520_L	0.636	0.76
409_F	493_A	0.636	0.76
564_I	577_P	0.636	0.76
287_I	298_A	0.636	0.76
408_L	492_L	0.635	0.76
348_F	358_L	0.635	0.76
308_L	313_L	0.635	0.76
594_T	598_L	0.634	0.76
302_A	375_L	0.634	0.76
236_K	257_D	0.633	0.76
527_E	533_T	0.632	0.76
569_T	573_I	0.631	0.76
530_N	534_A	0.629	0.76
477_K	502_K	0.629	0.76
181_F	198_Y	0.627	0.75
518_G	685_T	0.627	0.75
303_C	313_L	0.627	0.75
563_R	576_K	0.627	0.75
155_K	158_F	0.626	0.75
150_N	155_K	0.626	0.75
181_F	255_M	0.626	0.75
590_I	627_L	0.625	0.75
386_K	390_E	0.624	0.75
520_L	564_I	0.623	0.75
516_V	522_A	0.622	0.75
408_L	493_A	0.622	0.75
281_N	288_I	0.622	0.75
523_G	682_P	0.620	0.74
533_T	538_F	0.620	0.74
652_I	662_I	0.620	0.74
279_F	372_L	0.620	0.74
295_I	362_S	0.619	0.74
185_F	201_I	0.618	0.74
415_I	437_S	0.618	0.74
159_D	176_D	0.618	0.74
528_I	568_I	0.617	0.74
707_G	726_P	0.616	0.74
457_I	460_D	0.616	0.74
288_I	296_V	0.616	0.74
463_D	479_E	0.615	0.74
389_R	392_E	0.614	0.74
521_A	573_I	0.614	0.74
595_I	609_M	0.613	0.74
169_D	175_I	0.613	0.74
226_L	238_F	0.613	0.74
518_G	522_A	0.612	0.74
476_R	499_T	0.611	0.73
444_A	447_I	0.611	0.73
279_F	287_I	0.610	0.73
176_D	250_F	0.609	0.73
228_V	255_M	0.609	0.73
518_G	687_K	0.608	0.73
328_K	331_I	0.608	0.73
678_R	684_Y	0.607	0.73
236_K	251_Y	0.607	0.73
512_D	527_E	0.607	0.73
536_K	565_E	0.607	0.73
580_I	623_E	0.607	0.73
165_I	252_M	0.607	0.73
428_L	476_R	0.607	0.73
627_L	705_H	0.606	0.73
698_S	723_I	0.606	0.73
181_F	228_V	0.605	0.73
242_I	253_S	0.604	0.73
158_F	167_L	0.603	0.72
594_T	635_L	0.602	0.72
647_N	667_E	0.601	0.72
521_A	530_N	0.601	0.72
223_K	241_T	0.600	0.72
523_G	564_I	0.600	0.72
675_K	684_Y	0.600	0.72
647_N	665_K	0.599	0.72
521_A	578_Q	0.599	0.72
538_F	686_T	0.599	0.72
302_A	359_E	0.598	0.72
185_F	228_V	0.598	0.72
649_F	667_E	0.598	0.72
167_L	245_N	0.598	0.72
696_M	721_F	0.598	0.72
591_M	662_I	0.597	0.72
534_A	556_V	0.596	0.72
305_I	375_L	0.595	0.71
288_I	291_N	0.594	0.71
299_N	360_F	0.593	0.71
293_G	299_N	0.593	0.71
572_L	576_K	0.593	0.71
542_L	556_V	0.592	0.71
528_I	622_C	0.592	0.71
438_L	454_A	0.591	0.71
520_L	524_I	0.591	0.71
680_G	711_V	0.591	0.71
522_A	646_G	0.588	0.71
161_A	252_M	0.587	0.70
360_F	373_T	0.586	0.70
527_E	685_T	0.586	0.70
631_F	635_L	0.585	0.70
477_K	484_R	0.584	0.70
517_V	685_T	0.584	0.70
201_I	250_F	0.583	0.70
521_A	697_V	0.582	0.70
531_P	629_Q	0.582	0.70
517_V	529_R	0.581	0.70
521_A	524_I	0.581	0.70
538_F	556_V	0.581	0.70
395_F	417_D	0.580	0.70
543_K	551_A	0.580	0.70
534_A	537_G	0.579	0.69
414_R	437_S	0.579	0.69
517_V	573_I	0.578	0.69
228_V	238_F	0.578	0.69
163_D	254_I	0.577	0.69
236_K	242_I	0.577	0.69
443_S	475_N	0.576	0.69
528_I	705_H	0.575	0.69
582_Y	705_H	0.575	0.69
531_P	568_I	0.574	0.69
322_L	326_Q	0.572	0.68
181_F	242_I	0.572	0.68
275_F	284_D	0.571	0.68
517_V	687_K	0.571	0.68
281_N	299_N	0.569	0.68
574_L	700_K	0.569	0.68
567_I	572_L	0.569	0.68
572_L	691_T	0.569	0.68
590_I	594_T	0.568	0.68
405_G	480_F	0.568	0.68
202_D	228_V	0.568	0.68
517_V	565_E	0.566	0.68
302_A	373_T	0.565	0.68
182_C	253_S	0.565	0.68
242_I	250_F	0.563	0.67
197_L	202_D	0.563	0.67
662_I	725_L	0.563	0.67
577_P	641_V	0.562	0.67
514_L	529_R	0.562	0.67
629_Q	633_N	0.562	0.67
346_L	358_L	0.561	0.67
558_T	562_K	0.561	0.67
539_I	554_F	0.560	0.67
517_V	640_E	0.559	0.67
275_F	286_I	0.559	0.67
557_I	563_R	0.559	0.67
164_G	182_C	0.557	0.66
520_L	529_R	0.556	0.66
283_M	288_I	0.556	0.66
427_G	471_S	0.555	0.66
226_L	242_I	0.555	0.66
533_T	560_E	0.555	0.66
278_I	281_N	0.554	0.66
636_K	697_V	0.554	0.66
169_D	250_F	0.554	0.66
187_I	230_L	0.554	0.66
406_N	417_D	0.553	0.66
523_G	642_M	0.552	0.66
282_A	285_A	0.550	0.65
163_D	241_T	0.550	0.65
675_K	678_R	0.550	0.65
570_E	629_Q	0.549	0.65
150_N	154_F	0.548	0.65
423_S	429_S	0.547	0.65
286_I	297_K	0.547	0.65
166_V	255_M	0.547	0.65
597_L	641_V	0.547	0.65
159_D	178_N	0.546	0.65
518_G	529_R	0.546	0.65
423_S	433_I	0.546	0.65
384_M	387_E	0.546	0.65
405_G	482_F	0.545	0.65
574_L	691_T	0.545	0.65
683_F	690_G	0.545	0.65
161_A	254_I	0.544	0.65
285_A	301_S	0.544	0.65
626_Q	687_K	0.544	0.65
443_S	447_I	0.544	0.65
302_A	355_F	0.543	0.65
524_I	560_E	0.543	0.65
636_K	641_V	0.542	0.64
517_V	523_G	0.542	0.64
406_N	413_Y	0.541	0.64
326_Q	346_L	0.541	0.64
209_F	212_I	0.540	0.64
525_A	572_L	0.540	0.64
387_E	390_E	0.539	0.64
637_N	694_G	0.538	0.64
634_I	723_I	0.538	0.64
287_I	301_S	0.538	0.64
529_R	538_F	0.537	0.64
185_F	252_M	0.536	0.64
309_P	351_G	0.536	0.64
530_N	632_I	0.535	0.63
201_I	228_V	0.535	0.63
530_N	533_T	0.535	0.63
422_A	482_F	0.535	0.63
518_G	523_G	0.535	0.63
279_F	285_A	0.535	0.63
167_L	178_N	0.533	0.63
524_I	578_Q	0.533	0.63
287_I	360_F	0.532	0.63
273_E	277_E	0.531	0.63
225_E	258_I	0.531	0.63
678_R	681_E	0.530	0.63
438_L	482_F	0.530	0.63
625_N	628_K	0.529	0.63
413_Y	419_N	0.529	0.63
597_L	682_P	0.529	0.63
529_R	572_L	0.529	0.63
523_G	527_E	0.528	0.62
525_A	697_V	0.528	0.62
236_K	259_T	0.526	0.62
215_A	221_K	0.526	0.62
538_F	628_K	0.526	0.62
345_E	378_V	0.525	0.62
521_A	685_T	0.524	0.62
405_G	492_L	0.524	0.62
333_K	346_L	0.524	0.62
153_L	176_D	0.523	0.62
327_Q	362_S	0.523	0.62
405_G	423_S	0.523	0.62
274_R	297_K	0.523	0.62
521_A	533_T	0.522	0.61
288_I	295_I	0.522	0.61
533_T	564_I	0.521	0.61
428_L	433_I	0.521	0.61
177_A	180_S	0.520	0.61
641_V	669_I	0.520	0.61
517_V	564_I	0.519	0.61
599_N	603_N	0.518	0.61
399_F	408_L	0.518	0.61
197_L	242_I	0.517	0.61
529_R	537_G	0.516	0.61
594_T	628_K	0.516	0.61
597_L	642_M	0.515	0.60
346_L	357_E	0.515	0.60
520_L	571_F	0.515	0.60
237_L	243_T	0.515	0.60
279_F	376_R	0.515	0.60
182_C	188_N	0.514	0.60
516_V	523_G	0.514	0.60
201_I	226_L	0.514	0.60
269_F	273_E	0.514	0.60
520_L	528_I	0.514	0.60
366_I	370_Q	0.514	0.60
403_M	496_K	0.513	0.60
407_V	482_F	0.512	0.60
208_D	211_N	0.512	0.60
277_E	281_N	0.511	0.60
216_L	244_S	0.509	0.60
288_I	362_S	0.509	0.60
231_R	236_K	0.508	0.59
438_L	493_A	0.508	0.59
457_I	461_E	0.508	0.59
275_F	288_I	0.508	0.59
364_R	372_L	0.507	0.59
518_G	682_P	0.507	0.59
419_N	425_I	0.506	0.59
284_D	301_S	0.505	0.59
642_M	701_I	0.505	0.59
287_I	372_L	0.504	0.59
520_L	640_E	0.504	0.59
307_E	352_N	0.504	0.59
670_G	718_G	0.504	0.59
642_M	686_T	0.503	0.59
152_Q	155_K	0.503	0.59
521_A	577_P	0.503	0.59
527_E	626_Q	0.503	0.59
548_G	551_A	0.503	0.59
525_A	640_E	0.502	0.59
674_D	677_K	0.502	0.59
406_N	492_L	0.502	0.59
520_L	626_Q	0.502	0.59
224_G	228_V	0.502	0.59
295_I	321_F	0.502	0.59
517_V	525_A	0.501	0.58
294_R	315_K	0.500	0.58
537_G	564_I	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4gczA	2	0.4824	100	0.603	Contact Map
3a0rA	2	0.4404	100	0.613	Contact Map
4i5sA	2	0.5149	100	0.625	Contact Map
4r3aA	1	0.4187	100	0.679	Contact Map
4q20A	2	0.2995	100	0.719	Contact Map
3d36A	2	0.2954	100	0.72	Contact Map
4mpcA	2	0.4133	100	0.722	Contact Map
2q8gA	2	0.4079	100	0.724	Contact Map
4e01A	3	0.3889	100	0.725	Contact Map
2c2aA	2	0.3089	100	0.725	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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