GREMLIN Database
MANR - Transcriptional regulator ManR
UniProt: O31644 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 648 (623)
Sequences: 2258 (1982)
Seq/√Len: 79.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_R42_D5.6681.00
160_E229_R4.6401.00
97_R131_D4.2151.00
324_D400_R3.9751.00
357_K384_E3.9701.00
34_C39_I3.9101.00
410_K437_A3.8141.00
43_L47_E3.5461.00
144_L158_G3.4781.00
353_L388_A3.4711.00
104_D120_R3.4571.00
206_K257_A3.3771.00
123_V128_I3.3751.00
160_E164_R3.2221.00
638_N641_T3.2201.00
522_E587_K3.1981.00
143_D162_N3.1371.00
123_V131_D3.1091.00
586_L589_P3.0011.00
412_V442_I2.8861.00
598_S634_T2.8211.00
531_E548_A2.7521.00
415_C418_G2.7271.00
314_S320_D2.7081.00
514_P640_M2.6881.00
534_A548_A2.6881.00
142_F169_R2.6721.00
136_E148_S2.6391.00
144_L156_V2.6041.00
375_N381_H2.5671.00
426_R430_E2.5651.00
164_R274_E2.4691.00
123_V127_S2.4311.00
38_T42_D2.3821.00
465_A475_V2.3491.00
307_G328_I2.3111.00
515_F540_K2.2971.00
517_V639_V2.2791.00
14_L23_L2.2511.00
576_I604_A2.2371.00
164_R229_R2.2331.00
34_C42_D2.2171.00
324_D397_A2.1851.00
14_L28_F2.1271.00
525_H528_K2.0921.00
47_E58_L2.0911.00
159_N162_N2.0801.00
247_K272_E2.0721.00
425_L463_T2.0711.00
523_A532_Q2.0661.00
411_A461_I2.0611.00
47_E60_R2.0601.00
413_I429_I2.0421.00
533_L584_A2.0091.00
222_H281_H1.9991.00
28_F39_I1.9821.00
533_L602_M1.9811.00
368_I384_E1.9791.00
530_I548_A1.9761.00
591_E594_N1.9761.00
423_Q426_R1.9581.00
147_V157_E1.9551.00
529_L584_A1.9521.00
529_L600_V1.9301.00
102_A135_V1.9291.00
357_K364_F1.9141.00
589_P598_S1.9101.00
351_P385_E1.8961.00
98_M135_V1.8951.00
59_I69_H1.8921.00
411_A436_I1.8841.00
367_I391_T1.8791.00
538_F543_V1.8681.00
306_V335_L1.8631.00
551_A602_M1.8441.00
36_E40_R1.8431.00
535_T539_E1.8421.00
202_S261_R1.8331.00
350_N388_A1.8221.00
316_L369_D1.8221.00
415_C422_S1.8101.00
263_E269_R1.8051.00
90_R96_E1.8021.00
7_R38_T1.7901.00
477_S484_E1.7851.00
371_L390_L1.7731.00
56_A70_I1.7691.00
544_D577_K1.7581.00
630_V634_T1.7311.00
321_F394_F1.7291.00
341_R386_E1.7221.00
149_R152_L1.7051.00
312_R373_D1.6891.00
542_Y578_Q1.6841.00
22_Y67_Y1.6831.00
549_V553_M1.6821.00
534_A602_M1.6761.00
522_E588_E1.6711.00
313_V366_L1.6701.00
526_R592_W1.6661.00
14_L31_R1.6631.00
579_S606_K1.6471.00
138_W166_A1.6471.00
542_Y580_A1.6421.00
520_Q585_T1.6411.00
43_L58_L1.6361.00
62_P65_G1.6321.00
350_N385_E1.6321.00
223_T278_L1.6241.00
158_G163_K1.6031.00
338_V342_L1.6021.00
313_V394_F1.5981.00
363_L391_T1.5981.00
14_L32_V1.5801.00
308_H377_T1.5781.00
409_K492_I1.5731.00
327_L331_L1.5631.00
93_S96_E1.5621.00
5_N8_Q1.5510.99
531_E552_V1.5420.99
519_L585_T1.5370.99
43_L66_V1.5350.99
168_A222_H1.5330.99
61_K64_L1.5310.99
334_H393_H1.5310.99
484_E487_K1.5280.99
567_A597_V1.5240.99
8_Q45_V1.5210.99
415_C464_I1.5190.99
218_S281_H1.5050.99
349_A385_E1.5050.99
135_V146_L1.4950.99
327_L397_A1.4930.99
111_P155_K1.4920.99
313_V367_I1.4920.99
461_I476_V1.4820.99
565_G598_S1.4820.99
203_L258_C1.4710.99
317_K366_L1.4660.99
512_T583_I1.4620.99
25_V66_V1.4600.99
200_I220_L1.4600.99
26_Q36_E1.4550.99
207_H257_A1.4540.99
144_L163_K1.4530.99
314_S324_D1.4400.99
443_A446_D1.4390.99
310_I328_I1.4320.99
461_I474_I1.4260.99
543_V547_Y1.4250.99
516_L540_K1.4240.99
97_R127_S1.4200.99
524_E528_K1.4140.99
251_E279_T1.4130.99
309_L394_F1.4040.99
523_A529_L1.3980.99
581_I601_F1.3970.99
433_Y489_S1.3930.99
12_L46_I1.3890.99
637_T641_T1.3890.99
521_Q584_A1.3860.99
8_Q42_D1.3860.99
115_K125_R1.3860.99
457_I471_V1.3850.99
408_H437_A1.3840.99
218_S222_H1.3810.99
331_L390_L1.3810.99
527_Y531_E1.3810.99
518_F536_A1.3790.99
22_Y65_G1.3700.99
538_F548_A1.3610.99
256_F275_A1.3570.99
534_A551_A1.3540.99
326_D400_R1.3480.99
561_N592_W1.3460.98
252_Y279_T1.3440.98
462_S475_V1.3430.98
520_Q587_K1.3410.98
554_R560_T1.3370.98
102_A139_L1.3360.98
168_A225_L1.3310.98
145_T157_E1.3220.98
480_L488_L1.3160.98
321_F397_A1.3130.98
440_A457_I1.3110.98
11_I28_F1.3080.98
488_L492_I1.3060.98
26_Q30_D1.3030.98
350_N389_Y1.2980.98
548_A552_V1.2970.98
101_I135_V1.2890.98
37_K41_N1.2890.98
29_A39_I1.2880.98
533_L582_A1.2870.98
94_D131_D1.2770.98
338_V341_R1.2720.98
59_I67_Y1.2720.98
98_M131_D1.2700.98
526_R593_G1.2690.98
327_L400_R1.2680.98
551_A560_T1.2620.98
599_L634_T1.2590.98
417_M421_M1.2580.98
560_T569_P1.2490.98
15_L68_L1.2490.98
469_I472_P1.2480.98
541_G577_K1.2480.98
256_F272_E1.2460.97
29_A36_E1.2450.97
399_E428_K1.2450.97
537_L543_V1.2410.97
418_G421_M1.2400.97
363_L395_Q1.2390.97
34_C38_T1.2390.97
474_I484_E1.2370.97
37_K395_Q1.2360.97
547_Y604_A1.2360.97
117_I128_I1.2360.97
271_P274_E1.2330.97
150_Q153_G1.2320.97
363_L367_I1.2320.97
412_V457_I1.2320.97
98_M134_A1.2260.97
543_V604_A1.2170.97
585_T599_L1.2150.97
528_K531_E1.2130.97
374_I382_I1.2050.97
534_A538_F1.2040.97
113_S153_G1.2030.97
113_S116_D1.2020.97
60_R66_V1.2020.97
606_K609_D1.1990.97
639_V643_L1.1960.97
521_Q587_K1.1950.97
581_I616_L1.1940.97
579_S605_V1.1920.97
591_E596_K1.1900.97
353_L384_E1.1890.97
416_H464_I1.1840.97
410_K456_D1.1820.97
100_H121_H1.1800.97
29_A34_C1.1790.97
556_K559_A1.1760.96
204_Q211_F1.1680.96
415_C420_G1.1670.96
8_Q46_I1.1670.96
11_I46_I1.1630.96
538_F545_K1.1520.96
255_T275_A1.1470.96
517_V585_T1.1470.96
393_H396_A1.1460.96
249_K252_Y1.1460.96
147_V155_K1.1450.96
512_T516_L1.1440.96
114_A125_R1.1440.96
418_G422_S1.1420.96
586_L598_S1.1380.96
530_I551_A1.1360.96
553_M556_K1.1350.96
432_K489_S1.1310.96
4_I8_Q1.1300.96
94_D134_A1.1260.95
14_L18_E1.1240.95
555_E558_S1.1220.95
639_V642_F1.1190.95
230_I274_E1.1190.95
125_R153_G1.1190.95
195_F265_V1.1170.95
530_I534_A1.1110.95
636_E641_T1.1090.95
317_K321_F1.1050.95
550_H575_F1.1010.95
199_E203_L1.0990.95
327_L370_V1.0970.95
557_M560_T1.0970.95
115_K119_A1.0890.95
255_T279_T1.0890.95
429_I436_I1.0870.94
122_F592_W1.0850.94
364_F384_E1.0790.94
309_L367_I1.0790.94
520_Q586_L1.0780.94
512_T517_V1.0740.94
196_V224_L1.0730.94
491_F495_L1.0690.94
396_A400_R1.0680.94
351_P389_Y1.0680.94
555_E560_T1.0680.94
38_T41_N1.0670.94
127_S131_D1.0650.94
555_E559_A1.0620.94
302_L306_V1.0590.94
523_A586_L1.0590.94
330_G400_R1.0560.94
58_L61_K1.0540.94
230_I270_F1.0490.93
126_S129_K1.0480.93
35_S38_T1.0460.93
592_W600_V1.0460.93
334_H570_H1.0440.93
100_H120_R1.0430.93
310_I327_L1.0430.93
411_A492_I1.0430.93
518_F532_Q1.0410.93
560_T592_W1.0400.93
160_E274_E1.0360.93
128_I131_D1.0350.93
613_T617_F1.0310.93
102_A170_I1.0310.93
252_Y275_A1.0190.92
397_A400_R1.0180.92
367_I370_V1.0150.92
222_H226_M1.0140.92
571_A604_A1.0130.92
5_N45_V1.0080.92
592_W597_V1.0060.92
364_F368_I1.0010.92
428_K479_L0.9980.92
433_Y485_E0.9970.91
97_R123_V0.9970.91
118_A128_I0.9950.91
148_S154_L0.9950.91
310_I313_V0.9940.91
162_N165_K0.9920.91
530_I552_V0.9920.91
572_N605_V0.9910.91
41_N45_V0.9890.91
567_A592_W0.9880.91
537_L580_A0.9860.91
309_L370_V0.9860.91
425_L480_L0.9860.91
255_T282_I0.9830.91
517_V642_F0.9820.91
113_S152_L0.9800.91
277_Y351_P0.9770.91
211_F282_I0.9730.90
601_F620_L0.9730.90
139_L144_L0.9710.90
532_Q536_A0.9700.90
259_L263_E0.9690.90
312_R315_E0.9640.90
616_L620_L0.9640.90
367_I371_L0.9630.90
32_V39_I0.9610.90
468_N472_P0.9600.90
229_R274_E0.9600.90
279_T283_L0.9590.90
328_I332_N0.9560.90
587_K637_T0.9540.90
203_L261_R0.9540.90
106_L166_A0.9530.90
547_Y571_A0.9520.90
636_E642_F0.9490.89
447_L469_I0.9490.89
571_A575_F0.9480.89
135_V139_L0.9460.89
543_V548_A0.9450.89
550_H553_M0.9420.89
599_L630_V0.9390.89
393_H420_G0.9380.89
371_L382_I0.9350.89
311_N315_E0.9310.88
339_L343_S0.9240.88
251_E283_L0.9230.88
243_M276_V0.9220.88
565_G634_T0.9220.88
530_I602_M0.9210.88
547_Y551_A0.9210.88
142_F166_A0.9210.88
609_D612_M0.9200.88
546_D549_V0.9170.88
309_L373_D0.9160.88
284_G337_T0.9160.88
24_V65_G0.9150.88
212_T286_K0.9150.88
199_E258_C0.9110.87
626_Q629_F0.9110.87
548_A551_A0.9090.87
255_T258_C0.9050.87
526_R552_V0.9040.87
306_V332_N0.9030.87
197_T217_E0.9020.87
417_M420_G0.9010.87
409_K459_L0.9000.87
355_D359_M0.9000.87
529_L533_L0.8990.87
550_H571_A0.8970.87
201_K216_F0.8970.87
311_N322_H0.8960.86
536_A582_A0.8940.86
462_S473_H0.8940.86
411_A438_V0.8920.86
421_M464_I0.8920.86
335_L338_V0.8870.86
370_V373_D0.8860.86
432_K485_E0.8850.86
523_A584_A0.8830.86
228_R232_M0.8820.86
259_L278_L0.8790.85
399_E402_Q0.8770.85
440_A450_Y0.8750.85
213_D443_A0.8750.85
188_F224_L0.8720.85
337_T341_R0.8720.85
583_I642_F0.8700.85
160_E233_K0.8670.85
385_E388_A0.8650.84
306_V328_I0.8640.84
517_V583_I0.8630.84
118_A154_L0.8630.84
537_L582_A0.8600.84
330_G396_A0.8600.84
363_L398_I0.8590.84
527_Y552_V0.8580.84
158_G164_R0.8570.84
6_T10_E0.8570.84
561_N597_V0.8570.84
132_L136_E0.8510.83
106_L144_L0.8500.83
338_V382_I0.8470.83
438_V457_I0.8460.83
18_E23_L0.8450.83
310_I394_F0.8420.83
24_V29_A0.8410.83
554_R559_A0.8400.83
561_N614_K0.8370.82
492_I496_G0.8350.82
415_C463_T0.8350.82
532_Q535_T0.8330.82
372_E375_N0.8320.82
516_L582_A0.8310.82
513_T516_L0.8260.82
132_L135_V0.8250.82
350_N357_K0.8240.81
197_T216_F0.8220.81
128_I135_V0.8220.81
518_F582_A0.8210.81
285_G338_V0.8210.81
189_L192_E0.8200.81
112_V117_I0.8190.81
341_R348_V0.8190.81
514_P639_V0.8160.81
480_L485_E0.8140.81
312_R370_V0.8090.80
564_S592_W0.8090.80
11_I23_L0.8010.80
413_I426_R0.8000.80
236_I277_Y0.8000.80
283_L340_Q0.7990.79
435_Q489_S0.7990.79
563_G595_E0.7970.79
415_C419_I0.7960.79
7_R34_C0.7950.79
390_L420_G0.7950.79
306_V309_L0.7940.79
331_L393_H0.7940.79
554_R569_P0.7930.79
226_M230_I0.7920.79
426_R441_C0.7900.79
11_I42_D0.7900.79
533_L536_A0.7900.79
641_T644_S0.7890.79
339_L380_L0.7870.78
516_L542_Y0.7870.78
631_Q634_T0.7870.78
476_V480_L0.7850.78
25_V65_G0.7830.78
560_T617_F0.7830.78
552_V559_A0.7820.78
60_R65_G0.7810.78
199_E261_R0.7810.78
5_N42_D0.7800.78
68_L84_T0.7790.78
631_Q635_K0.7780.78
371_L387_A0.7780.78
222_H393_H0.7780.78
125_R420_G0.7770.78
442_I450_Y0.7770.78
255_T259_L0.7770.78
306_V310_I0.7770.78
113_S125_R0.7770.78
571_A576_I0.7770.78
41_N44_K0.7750.77
302_L332_N0.7740.77
469_I473_H0.7740.77
633_L642_F0.7730.77
554_R570_H0.7700.77
111_P153_G0.7680.77
284_G393_H0.7670.77
15_L66_V0.7670.77
91_Q100_H0.7640.76
366_L370_V0.7640.76
305_V309_L0.7630.76
428_K432_K0.7610.76
249_K279_T0.7590.76
524_E588_E0.7570.76
252_Y283_L0.7570.76
213_D445_A0.7570.76
476_V484_E0.7560.76
246_V276_V0.7550.75
522_E539_E0.7540.75
640_M644_S0.7520.75
252_Y272_E0.7520.75
113_S149_R0.7520.75
418_G424_L0.7470.75
393_H400_R0.7460.75
551_A571_A0.7450.75
338_V383_P0.7450.75
252_Y255_T0.7440.74
47_E66_V0.7390.74
450_Y457_I0.7390.74
158_G229_R0.7390.74
111_P152_L0.7390.74
70_I78_L0.7370.74
342_L386_E0.7370.74
334_H386_E0.7360.74
330_G423_Q0.7350.74
533_L551_A0.7340.73
526_R561_N0.7340.73
414_V466_L0.7330.73
348_V389_Y0.7300.73
351_P356_I0.7290.73
37_K42_D0.7270.73
418_G464_I0.7260.73
278_L281_H0.7260.73
580_A604_A0.7250.73
104_D121_H0.7240.72
460_V469_I0.7240.72
586_L590_L0.7240.72
121_H128_I0.7240.72
603_L621_S0.7240.72
63_G95_K0.7230.72
547_Y569_P0.7230.72
415_C421_M0.7230.72
605_V617_F0.7210.72
417_M422_S0.7200.72
4_I171_S0.7180.72
303_P332_N0.7180.72
356_I388_A0.7180.72
550_H572_N0.7170.72
68_L600_V0.7150.71
93_S97_R0.7140.71
271_P281_H0.7130.71
342_L383_P0.7130.71
40_R621_S0.7110.71
478_P484_E0.7110.71
536_A584_A0.7090.71
342_L380_L0.7090.71
125_R129_K0.7060.71
415_C443_A0.7060.71
561_N593_G0.7050.70
334_H389_Y0.7040.70
537_L542_Y0.7040.70
472_P491_F0.7030.70
425_L485_E0.7020.70
15_L29_A0.7010.70
37_K66_V0.7000.70
164_R226_M0.7000.70
560_T605_V0.6990.70
533_L592_W0.6980.70
572_N614_K0.6980.70
203_L257_A0.6970.70
547_Y552_V0.6970.70
632_K635_K0.6960.69
350_N387_A0.6950.69
524_E586_L0.6950.69
583_I601_F0.6930.69
325_Q329_N0.6920.69
139_L156_V0.6920.69
518_F533_L0.6920.69
312_R316_L0.6910.69
410_K439_M0.6890.69
324_D399_E0.6880.69
247_K252_Y0.6880.69
348_V385_E0.6880.69
562_I623_L0.6870.68
480_L484_E0.6870.68
102_A156_V0.6860.68
113_S150_Q0.6860.68
345_D380_L0.6860.68
184_I187_K0.6850.68
196_V262_L0.6850.68
58_L470_T0.6840.68
341_R350_N0.6830.68
623_L633_L0.6830.68
526_R558_S0.6830.68
260_Q263_E0.6830.68
330_G393_H0.6830.68
252_Y276_V0.6820.68
433_Y496_G0.6800.68
246_V252_Y0.6790.68
617_F621_S0.6770.67
204_Q445_A0.6750.67
531_E549_V0.6740.67
18_E27_D0.6740.67
563_G592_W0.6740.67
4_I49_Y0.6730.67
623_L629_F0.6730.67
487_K512_T0.6700.67
365_H368_I0.6690.66
69_H72_E0.6690.66
91_Q96_E0.6680.66
411_A459_L0.6670.66
460_V471_V0.6670.66
44_K66_V0.6660.66
7_R11_I0.6660.66
160_E163_K0.6640.66
144_L166_A0.6630.66
252_Y256_F0.6630.66
11_I32_V0.6630.66
80_Q84_T0.6620.66
352_M389_Y0.6620.66
35_S314_S0.6610.65
237_S273_E0.6610.65
478_P576_I0.6610.65
98_M138_W0.6590.65
24_V27_D0.6570.65
396_A438_V0.6570.65
620_L624_S0.6570.65
62_P216_F0.6570.65
152_L388_A0.6560.65
56_A78_L0.6550.65
588_E598_S0.6550.65
554_R592_W0.6550.65
327_L330_G0.6530.65
15_L46_I0.6510.64
270_F278_L0.6510.64
338_V346_L0.6490.64
506_F510_N0.6490.64
166_A170_I0.6490.64
169_R388_A0.6490.64
222_H225_L0.6480.64
37_K65_G0.6470.64
314_S322_H0.6460.64
97_R100_H0.6450.64
184_I191_Y0.6450.64
101_I139_L0.6430.63
330_G395_Q0.6420.63
259_L275_A0.6380.63
547_Y606_K0.6360.62
113_S129_K0.6360.62
520_Q524_E0.6360.62
259_L262_L0.6350.62
520_Q584_A0.6340.62
584_A602_M0.6330.62
557_M592_W0.6330.62
199_E262_L0.6330.62
129_K154_L0.6330.62
114_A128_I0.6320.62
100_H104_D0.6300.62
249_K283_L0.6290.62
200_I204_Q0.6290.62
34_C313_V0.6280.62
212_T215_T0.6270.61
259_L276_V0.6250.61
581_I620_L0.6240.61
321_F324_D0.6240.61
543_V576_I0.6240.61
453_K457_I0.6230.61
203_L254_W0.6230.61
388_A391_T0.6220.61
521_Q586_L0.6220.61
146_L383_P0.6210.61
554_R602_M0.6210.61
113_S151_R0.6200.61
118_A123_V0.6190.60
508_M515_F0.6160.60
551_A592_W0.6160.60
78_L81_Q0.6150.60
130_K422_S0.6150.60
558_S561_N0.6150.60
551_A612_M0.6150.60
41_N547_Y0.6150.60
374_I378_F0.6140.60
259_L266_F0.6130.60
530_I560_T0.6110.59
321_F398_I0.6110.59
330_G397_A0.6110.59
561_N567_A0.6100.59
129_K148_S0.6100.59
302_L377_T0.6090.59
153_G418_G0.6090.59
410_K440_A0.6080.59
231_K267_A0.6080.59
192_E228_R0.6080.59
430_E434_H0.6070.59
156_V545_K0.6060.59
392_L396_A0.6060.59
223_T331_L0.6050.59
40_R445_A0.6050.59
444_K466_L0.6020.58
568_I581_I0.6020.58
62_P66_V0.6020.58
377_T380_L0.6020.58
53_H56_A0.6000.58
130_K133_Y0.6000.58
342_L382_I0.5990.58
537_L547_Y0.5990.58
132_L154_L0.5990.58
525_H531_E0.5980.58
25_V60_R0.5980.58
486_K588_E0.5970.58
429_I461_I0.5960.58
98_M121_H0.5960.58
576_I580_A0.5950.57
485_E496_G0.5950.57
397_A401_M0.5950.57
45_V48_D0.5950.57
28_F42_D0.5930.57
215_T285_G0.5930.57
599_L604_A0.5930.57
350_N360_Y0.5930.57
529_L536_A0.5930.57
236_I477_S0.5920.57
233_K274_E0.5920.57
589_P596_K0.5900.57
310_I367_I0.5900.57
12_L142_F0.5900.57
395_Q419_I0.5880.57
446_D449_D0.5880.57
368_I558_S0.5860.56
18_E22_Y0.5860.56
70_I73_Q0.5860.56
14_L413_I0.5850.56
34_C43_L0.5850.56
353_L385_E0.5840.56
263_E266_F0.5830.56
609_D613_T0.5830.56
351_P418_G0.5820.56
259_L268_I0.5820.56
263_E270_F0.5820.56
29_A286_K0.5820.56
545_K549_V0.5820.56
313_V318_M0.5810.56
94_D97_R0.5800.55
195_F266_F0.5800.55
599_L642_F0.5790.55
134_A137_E0.5790.55
11_I328_I0.5790.55
140_K145_T0.5790.55
351_P388_A0.5780.55
102_A310_I0.5770.55
216_F220_L0.5770.55
592_W606_K0.5760.55
408_H424_L0.5760.55
396_A399_E0.5750.55
277_Y389_Y0.5750.55
410_K458_D0.5740.55
557_M561_N0.5740.55
632_K641_T0.5740.55
317_K576_I0.5730.55
337_T340_Q0.5710.54
572_N576_I0.5700.54
282_I390_L0.5690.54
319_M398_I0.5690.54
156_V198_K0.5680.54
348_V390_L0.5680.54
153_G424_L0.5680.54
529_L616_L0.5670.54
577_K580_A0.5670.54
49_Y53_H0.5650.54
316_L370_V0.5640.53
371_L391_T0.5640.53
281_H337_T0.5640.53
113_S434_H0.5640.53
323_K401_M0.5640.53
41_N125_R0.5630.53
537_L541_G0.5630.53
124_N127_S0.5620.53
554_R571_A0.5620.53
601_F604_A0.5600.53
34_C41_N0.5600.53
284_G346_L0.5600.53
57_Q69_H0.5590.53
514_P633_L0.5590.53
236_I274_E0.5590.53
224_L228_R0.5590.53
415_C425_L0.5580.53
370_V394_F0.5580.53
356_I509_L0.5580.53
492_I508_M0.5580.53
529_L590_L0.5570.53
79_S462_S0.5570.53
105_L189_L0.5570.53
546_D575_F0.5570.53
395_Q399_E0.5560.52
419_I422_S0.5560.52
200_I258_C0.5550.52
113_S337_T0.5550.52
255_T278_L0.5540.52
115_K152_L0.5540.52
107_M163_K0.5540.52
356_I391_T0.5540.52
536_A539_E0.5540.52
433_Y461_I0.5530.52
335_L353_L0.5530.52
29_A65_G0.5530.52
199_E202_S0.5530.52
519_L587_K0.5520.52
192_E195_F0.5520.52
544_D575_F0.5520.52
4_I41_N0.5520.52
415_C458_D0.5510.52
6_T9_K0.5510.52
60_R434_H0.5510.52
281_H346_L0.5510.52
219_L477_S0.5510.52
283_L344_Y0.5500.52
561_N595_E0.5490.52
623_L634_T0.5490.52
528_K532_Q0.5490.52
214_E284_G0.5480.51
537_L569_P0.5480.51
413_I422_S0.5480.51
326_D330_G0.5480.51
100_H123_V0.5470.51
5_N569_P0.5470.51
73_Q78_L0.5460.51
462_S468_N0.5450.51
145_T354_N0.5450.51
68_L78_L0.5440.51
324_D393_H0.5440.51
105_L146_L0.5440.51
569_P599_L0.5440.51
532_Q584_A0.5430.51
303_P328_I0.5430.51
315_E318_M0.5430.51
150_Q411_A0.5430.51
416_H444_K0.5420.51
253_Q256_F0.5400.50
520_Q523_A0.5400.50
168_A281_H0.5400.50
214_E223_T0.5390.50
22_Y64_L0.5390.50
330_G428_K0.5380.50
428_K480_L0.5380.50
561_N621_S0.5380.50
200_I219_L0.5380.50
309_L371_L0.5370.50
42_D117_I0.5370.50
367_I390_L0.5370.50
320_D324_D0.5360.50
25_V29_A0.5350.50
614_K617_F0.5350.50
40_R156_V0.5350.50
439_M457_I0.5350.50
283_L460_V0.5350.50
560_T567_A0.5350.50
341_R388_A0.5340.50
30_D633_L0.5340.50
438_V461_I0.5330.49
159_N408_H0.5330.49
263_E271_P0.5330.49
459_L488_L0.5330.49
311_N381_H0.5320.49
215_T338_V0.5320.49
516_L520_Q0.5310.49
539_E640_M0.5310.49
37_K249_K0.5310.49
24_V594_N0.5310.49
77_W486_K0.5300.49
605_V613_T0.5300.49
200_I623_L0.5300.49
613_T616_L0.5280.49
42_D620_L0.5270.49
601_F623_L0.5260.49
476_V485_E0.5260.49
284_G480_L0.5260.49
88_S528_K0.5250.48
341_R345_D0.5250.48
104_D117_I0.5240.48
132_L146_L0.5240.48
215_T218_S0.5230.48
123_V363_L0.5230.48
160_E234_Q0.5230.48
491_F494_Q0.5230.48
593_G597_V0.5220.48
429_I488_L0.5220.48
144_L508_M0.5220.48
193_V224_L0.5210.48
338_V390_L0.5210.48
256_F306_V0.5210.48
246_V279_T0.5210.48
195_F199_E0.5210.48
317_K369_D0.5210.48
629_F634_T0.5210.48
263_E275_A0.5200.48
120_R195_F0.5200.48
25_V40_R0.5200.48
238_L243_M0.5190.48
196_V310_I0.5180.48
196_V199_E0.5180.48
154_L313_V0.5170.47
144_L638_N0.5170.47
222_H389_Y0.5170.47
142_F162_N0.5160.47
490_A590_L0.5160.47
207_H254_W0.5150.47
535_T538_F0.5140.47
163_K229_R0.5140.47
129_K389_Y0.5130.47
316_L366_L0.5130.47
254_W416_H0.5130.47
413_I461_I0.5130.47
338_V348_V0.5120.47
421_M557_M0.5120.47
105_L156_V0.5120.47
460_V472_P0.5110.47
592_W602_M0.5110.47
164_R277_Y0.5100.46
461_I495_L0.5100.46
616_L619_E0.5100.46
564_S568_I0.5090.46
347_S370_V0.5090.46
559_A592_W0.5090.46
391_T473_H0.5080.46
192_E266_F0.5080.46
36_E39_I0.5080.46
443_A447_L0.5070.46
356_I374_I0.5070.46
223_T644_S0.5060.46
101_I454_H0.5060.46
164_R225_L0.5050.46
296_N514_P0.5050.46
585_T642_F0.5040.46
281_H393_H0.5030.46
105_L154_L0.5020.45
80_Q297_L0.5020.45
26_Q412_V0.5020.45
114_A118_A0.5020.45
171_S387_A0.5020.45
539_E583_I0.5010.45
330_G476_V0.5000.45
562_I568_I0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4r6iA 2 0.7068 100 0.434 Contact Map
3sqnA 2 0.6991 100 0.487 Contact Map
1h99A 2 0.338 100 0.76 Contact Map
1a6jA 4 0.2315 100 0.793 Contact Map
3oxpA 2 0.2176 100 0.795 Contact Map
3bjvA 2 0.2191 100 0.797 Contact Map
2a0jA 1 0.2191 100 0.797 Contact Map
3urrA 2 0.2238 100 0.798 Contact Map
2oqtA 2 0.2207 100 0.798 Contact Map
2oq3A 1 0.2176 100 0.798 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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