GREMLIN Database
YJCF - Uncharacterized N-acetyltransferase YjcF
UniProt: O31628 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (128)
Sequences: 3244 (2493)
Seq/√Len: 220.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_E119_Y3.1151.00
57_G90_L2.9861.00
111_V121_V2.6121.00
105_N127_F2.3921.00
20_E34_E2.1511.00
89_A92_K2.1501.00
108_T126_E2.1371.00
126_E133_P2.0751.00
18_V72_C1.9721.00
84_G117_H1.9641.00
54_V77_H1.8021.00
60_R69_E1.8021.00
111_V135_L1.8011.00
18_V74_L1.7911.00
14_D48_Y1.7641.00
122_L136_Q1.7351.00
12_L16_F1.7281.00
46_V53_P1.7131.00
87_M117_H1.6981.00
47_V82_V1.6801.00
21_E74_L1.6371.00
68_L87_M1.6211.00
56_A72_C1.6151.00
48_Y53_P1.6041.00
21_E25_K1.5791.00
55_G73_V1.5641.00
47_V55_G1.5531.00
91_E102_F1.5201.00
84_G116_K1.5071.00
115_K121_V1.5031.00
111_V115_K1.5031.00
127_F136_Q1.4791.00
101_G138_M1.4731.00
128_L131_G1.4581.00
122_L138_M1.4391.00
128_L133_P1.4301.00
112_P115_K1.4101.00
84_G88_K1.4001.00
105_N136_Q1.3591.00
29_V130_A1.3511.00
17_Y21_E1.3181.00
52_K76_S1.3141.00
29_V132_I1.3111.00
123_S136_Q1.2951.00
15_A46_V1.2831.00
65_Y103_I1.2831.00
45_I93_A1.2771.00
103_I136_Q1.2681.00
93_A96_D1.2551.00
57_G71_I1.2461.00
16_F35_I1.2431.00
20_E31_A1.2381.00
49_D77_H1.2381.00
105_N129_D1.2321.00
45_I90_L1.2271.00
27_Q107_Q1.2241.00
71_I87_M1.2241.00
43_E93_A1.2091.00
85_I89_A1.2041.00
121_V135_L1.1921.00
21_E32_E1.1491.00
15_A56_A1.1431.00
49_D54_V1.1421.00
20_E24_V1.1291.00
103_I138_M1.0591.00
67_K103_I1.0521.00
20_E25_K1.0131.00
66_G99_A1.0051.00
88_K92_K0.9911.00
20_E35_I0.9871.00
77_H80_A0.9851.00
59_W94_A0.9841.00
24_V31_A0.9831.00
93_A97_G0.9771.00
108_T111_V0.9711.00
14_D17_Y0.9631.00
13_K16_F0.9421.00
92_K96_D0.9341.00
107_Q134_H0.9301.00
60_R67_K0.9301.00
68_L71_I0.9240.99
10_E14_D0.9190.99
38_L60_R0.9170.99
26_E78_R0.9080.99
45_I57_G0.9040.99
55_G86_I0.8980.99
62_K65_Y0.8940.99
94_A102_F0.8850.99
61_M99_A0.8840.99
43_E97_G0.8760.99
37_E40_N0.8730.99
65_Y101_G0.8640.99
110_A113_F0.8610.99
67_K105_N0.8550.99
25_K30_P0.8540.99
89_A93_A0.8520.99
9_E13_K0.8400.99
68_L90_L0.8280.99
85_I88_K0.8260.99
67_K104_L0.8240.99
42_S60_R0.8160.99
83_G113_F0.8060.99
32_E35_I0.8060.99
54_V82_V0.8060.99
57_G86_I0.8040.99
108_T133_P0.7990.99
16_F20_E0.7830.98
106_A137_M0.7770.98
49_D52_K0.7760.98
49_D80_A0.7730.98
52_K74_L0.7700.98
59_W93_A0.7700.98
55_G82_V0.7630.98
88_K117_H0.7620.98
102_F119_Y0.7510.98
48_Y51_E0.7510.98
11_Q46_V0.7380.97
18_V53_P0.7380.97
38_L62_K0.7370.97
74_L77_H0.7340.97
21_E76_S0.7290.97
17_Y37_E0.7240.97
81_G84_G0.7070.97
108_T135_L0.7050.97
10_E40_N0.7040.97
91_E117_H0.7000.97
26_E75_K0.6890.96
47_V85_I0.6890.96
68_L102_F0.6880.96
42_S61_M0.6760.96
82_V85_I0.6740.96
39_E69_E0.6740.96
44_H56_A0.6730.96
111_V126_E0.6620.95
45_I89_A0.6530.95
45_I59_W0.6530.95
11_Q15_A0.6460.95
23_F26_E0.6450.95
80_A83_G0.6420.94
18_V56_A0.6410.94
36_D58_R0.6350.94
30_P34_E0.6350.94
47_V54_V0.6270.94
13_K35_I0.6200.93
129_D132_I0.6190.93
126_E135_L0.6180.93
121_V126_E0.6170.93
68_L119_Y0.6140.93
73_V82_V0.6120.93
29_V129_D0.6100.93
23_F107_Q0.6090.93
20_E30_P0.6040.92
38_L41_E0.6020.92
104_L114_Y0.5980.92
92_K95_A0.5940.92
13_K37_E0.5860.91
115_K120_R0.5840.91
23_F27_Q0.5790.91
24_V34_E0.5770.91
104_L137_M0.5760.91
12_L39_E0.5740.90
86_I89_A0.5710.90
20_E32_E0.5660.90
66_G97_G0.5630.90
94_A99_A0.5610.89
55_G83_G0.5560.89
69_E107_Q0.5510.89
66_G94_A0.5510.89
68_L104_L0.5480.88
14_D53_P0.5380.87
83_G110_A0.5380.87
79_S84_G0.5370.87
61_M66_G0.5300.87
24_V30_P0.5270.86
123_S126_E0.5240.86
36_D39_E0.5220.86
77_H82_V0.5210.86
60_R66_G0.5210.86
37_E41_E0.5210.86
83_G114_Y0.5190.86
13_K17_Y0.5170.85
58_R70_R0.5170.85
96_D99_A0.5160.85
104_L110_A0.5140.85
26_E107_Q0.5110.85
27_Q134_H0.5090.84
30_P130_A0.5060.84
94_A98_G0.5050.84
63_D67_K0.5040.84
31_A130_A0.5030.84
14_D18_V0.5030.84
70_R107_Q0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2g0bA 4 0.9857 99.9 0.416 Contact Map
1q2yA 1 0.9929 99.9 0.42 Contact Map
3p2hA 1 0.9429 99.9 0.439 Contact Map
1kzfA 1 0.9071 99.9 0.441 Contact Map
1xebA 2 0.9857 99.9 0.451 Contact Map
2jdcA 1 0.9643 99.9 0.456 Contact Map
1ro5A 5 0.9929 99.9 0.459 Contact Map
3efaA 2 0.9929 99.9 0.467 Contact Map
1y9wA 2 0.9857 99.8 0.583 Contact Map
3gy9A 3 0.9429 99.7 0.599 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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