GREMLIN Database
YJCA - Sporulation protein YjcA
UniProt: O31623 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 118 (110)
Sequences: 136 (114)
Seq/√Len: 10.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_F70_Y4.5221.00
18_L99_L4.4571.00
84_C92_A3.7860.99
34_L67_L3.3630.97
63_I103_G2.6150.89
43_D47_N2.3380.82
21_L27_I1.9910.70
33_S95_L1.9700.69
29_A44_A1.8170.63
34_L94_W1.8070.62
10_L96_I1.7830.61
87_V112_V1.6960.57
20_R38_E1.6950.57
59_V63_I1.6910.57
20_R65_E1.6790.56
30_P34_L1.6250.54
38_E51_Y1.5480.50
8_I100_A1.4950.48
26_T107_I1.4430.45
51_Y73_T1.4360.45
78_A112_V1.4150.44
97_L101_I1.4140.44
40_E48_I1.3830.42
75_V91_A1.3690.42
60_R68_S1.3430.41
57_T77_C1.3390.40
38_E98_L1.3330.40
75_V80_F1.3240.40
8_I104_L1.2820.38
4_N99_L1.2790.38
24_F106_G1.2720.37
29_A54_I1.2700.37
30_P98_L1.2610.37
70_Y87_V1.2510.36
4_N110_T1.2450.36
37_E83_L1.2130.35
11_L92_A1.2090.35
15_V78_A1.1940.34
8_I44_A1.1830.33
54_I95_L1.1830.33
78_A101_I1.1730.33
82_I94_W1.1720.33
80_F112_V1.1590.32
20_R43_D1.1510.32
53_V56_G1.1400.32
22_L62_F1.1260.31
16_F65_E1.1100.30
21_L28_M1.0970.30
12_S93_Q1.0390.28
38_E50_T1.0280.27
26_T30_P1.0040.26
36_H82_I0.9960.26
12_S105_A0.9850.26
99_L102_A0.9810.25
36_H68_S0.9810.25
28_M67_L0.9650.25
55_K70_Y0.9640.25
7_T29_A0.9600.25
62_F108_I0.9560.25
37_E98_L0.9560.25
43_D49_E0.9510.24
4_N95_L0.9470.24
13_L44_A0.9410.24
36_H52_I0.9410.24
31_L110_T0.9380.24
42_K81_L0.9100.23
28_M31_L0.9070.23
20_R51_Y0.9020.23
11_L83_L0.8960.23
22_L85_Q0.8940.22
26_T65_E0.8900.22
80_F96_I0.8880.22
6_L62_F0.8810.22
37_E54_I0.8760.22
66_L94_W0.8750.22
18_L91_A0.8710.22
52_I82_I0.8690.22
60_R64_G0.8640.21
7_T107_I0.8630.21
44_A80_F0.8570.21
49_E53_V0.8340.21
61_A88_I0.8340.21
26_T51_Y0.8240.20
20_R40_E0.8170.20
16_F64_G0.8110.20
75_V99_L0.8100.20
62_F110_T0.8040.20
16_F68_S0.8040.20
5_G103_G0.8020.20
96_I99_L0.7930.19
23_V46_G0.7930.19
24_F109_E0.7900.19
79_G98_L0.7770.19
12_S84_C0.7560.18
79_G99_L0.7560.18
42_K70_Y0.7550.18
33_S70_Y0.7500.18
13_L109_E0.7480.18
37_E53_V0.7480.18
50_T65_E0.7360.18
6_L78_A0.7360.18
58_G61_A0.7290.17
80_F87_V0.7280.17
42_K83_L0.7260.17
20_R50_T0.7230.17
40_E81_L0.7220.17
62_F86_A0.7210.17
79_G101_I0.7180.17
45_D73_T0.7020.17
5_G60_R0.7020.17
80_F108_I0.7020.17
61_A86_A0.6950.17
30_P94_W0.6860.16
31_L80_F0.6820.16
5_G56_G0.6800.16
13_L86_A0.6760.16
31_L86_A0.6760.16
41_E52_I0.6750.16
10_L60_R0.6670.16
7_T44_A0.6520.15
42_K47_N0.6510.15
44_A79_G0.6430.15
36_H65_E0.6410.15
12_S103_G0.6410.15
22_L108_I0.6400.15
36_H54_I0.6320.15
8_I50_T0.6270.15
19_A35_F0.6260.15
107_I112_V0.6200.15
20_R37_E0.6180.15
47_N60_R0.6160.15
5_G88_I0.6150.15
70_Y109_E0.6100.14
63_I100_A0.6080.14
40_E90_Q0.6060.14
84_C93_Q0.6030.14
28_M94_W0.5980.14
9_V110_T0.5940.14
10_L82_I0.5930.14
10_L50_T0.5920.14
80_F100_A0.5800.14
67_L74_G0.5760.14
75_V101_I0.5660.13
81_L96_I0.5660.13
16_F60_R0.5650.13
34_L74_G0.5610.13
83_L95_L0.5600.13
59_V77_C0.5580.13
13_L104_L0.5560.13
41_E68_S0.5490.13
9_V37_E0.5490.13
47_N106_G0.5400.13
16_F100_A0.5390.13
15_V104_L0.5380.13
47_N107_I0.5360.13
40_E47_N0.5280.13
90_Q106_G0.5250.13
19_A34_L0.5240.12
26_T34_L0.5160.12
57_T96_I0.5110.12
9_V13_L0.5060.12
9_V33_S0.5060.12
39_K51_Y0.5040.12
42_K50_T0.5020.12
51_Y62_F0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4q9hA 1 1 10.1 0.953 Contact Map
4q4hB 1 0.9322 10 0.953 Contact Map
4hw9A 3 0.7458 7.7 0.955 Contact Map
3zdqA 2 0.9576 7.1 0.956 Contact Map
4a82A 2 0.9746 6.7 0.956 Contact Map
2mfrA 1 0.3051 5.9 0.958 Contact Map
4f4cA 1 0.9746 5.8 0.958 Contact Map
4ry2A 2 0.9661 5.7 0.958 Contact Map
4hl7A 4 0.8898 5.1 0.959 Contact Map
3wmgA 1 0.9576 5.1 0.959 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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