YJBQ - BACSU - GREMLIN Contacts

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YJBQ - Putative Na(+)/H(+) antiporter YjbQ

UniProt:	O31615	Sequences: MAHTSVASLVVVLIVAFLTPILLHRFKLSIPVVVAEIIMGLIIGKSGLNLVVEGDTWLQTLSMLGFIFLMFLSGLEIDFSSFEKGKKKQFLPNGKEAPNTFAAASVIFVGIFILSLLLSYGFVLAGFIQNAFLMTLIISTISLGVVVPTLKEERIMNSNIGQIILLVAVIADLATMILLAVFSSLYGEDSGNMWLLMILFAAGVVLYFFGRVFKHRSFVQSMSKGTIQIGTRAIFTLIIVLVALSESLGAENILGAFLAGVLVSLLSPNKELVQQLDSFGYGFLIPIFFVMVGVKLDIWTLFQDKTILIMIPLLLLALLVSKIIPVMYLKKWYDNRTIFASGFLLTSTLSLVIAAATIGQQLHVISTNMSGALILVAVIASIFTPICFKKLYKREEQPEEKKTITFIGANQMTLPVTLELPEEEYDVRVVHVYQENAEEKLSESVFAVETISDYEHETLESLGIFETDILVVATGNEDMNADIALLAKDKGTERVIASVGSPEHEAALKEQGISIFSILLSTKTLLRALIEAPGVMKLLTNQESSLYQINMENSKYDGVILREFPLTGDVIFVRIFRGVDSIVPHGDTRLKLGDRLIVTGSRGYVTDLKKTLEG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	614 (506)
Sequences:	3403 (2313)
Seq/√Len:	102.8

ECOLI - KEFC KEFB YBAL
BACSU - YJBQ
HALSA - Q9HNK1
SULSO - Q97UN8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
470_L	487_A	6.696	1.00
391_L	394_R	5.572	1.00
389_K	393_K	4.641	1.00
199_L	211_R	3.578	1.00
472_V	484_A	3.535	1.00
406_F	417_T	3.433	1.00
327_M	342_G	3.415	1.00
198_I	211_R	3.362	1.00
403_T	468_D	3.358	1.00
391_L	395_E	3.286	1.00
203_G	211_R	3.251	1.00
155_I	160_I	3.037	1.00
198_I	202_A	2.925	1.00
112_F	115_S	2.895	1.00
204_V	211_R	2.735	1.00
315_L	379_I	2.723	1.00
484_A	513_I	2.705	1.00
401_K	466_E	2.671	1.00
112_F	116_L	2.657	1.00
195_L	199_L	2.636	1.00
390_K	394_R	2.626	1.00
194_W	198_I	2.564	1.00
327_M	335_N	2.529	1.00
210_G	213_F	2.503	1.00
488_K	495_V	2.420	1.00
200_F	204_V	2.404	1.00
488_K	514_S	2.304	1.00
209_F	213_F	2.248	1.00
485_L	511_Q	2.227	1.00
312_P	316_L	2.225	1.00
200_F	211_R	2.215	1.00
14_I	236_T	2.213	1.00
109_V	325_P	2.202	1.00
314_L	376_V	2.201	1.00
472_V	480_N	2.192	1.00
199_L	212_V	2.149	1.00
199_L	213_F	2.116	1.00
366_S	369_M	2.115	1.00
389_K	392_Y	2.096	1.00
472_V	483_I	2.043	1.00
460_E	465_F	2.040	1.00
317_A	321_S	2.038	1.00
17_F	236_T	1.987	1.00
464_I	470_L	1.980	1.00
402_K	468_D	1.969	1.00
203_G	212_V	1.967	1.00
107_I	136_L	1.960	1.00
464_I	491_G	1.955	1.00
356_A	373_L	1.954	1.00
271_E	275_Q	1.950	1.00
405_T	464_I	1.934	1.00
347_S	384_T	1.927	1.00
469_I	530_I	1.915	1.00
405_T	467_T	1.911	1.00
198_I	213_F	1.903	1.00
494_R	514_S	1.901	1.00
327_M	331_K	1.899	1.00
113_I	117_L	1.853	1.00
216_R	267_S	1.842	1.00
209_F	212_V	1.837	1.00
471_V	526_L	1.816	1.00
372_A	376_V	1.806	1.00
206_L	209_F	1.804	1.00
360_Q	370_S	1.796	1.00
136_L	178_L	1.794	1.00
203_G	207_Y	1.789	1.00
407_I	470_L	1.775	1.00
343_F	387_C	1.766	1.00
115_S	118_L	1.764	1.00
56_T	59_Q	1.764	1.00
318_L	376_V	1.760	1.00
137_I	356_A	1.759	1.00
301_L	375_L	1.757	1.00
115_S	119_S	1.748	1.00
352_V	377_A	1.741	1.00
517_S	520_L	1.727	1.00
390_K	393_K	1.715	1.00
521_S	525_L	1.700	1.00
19_T	42_I	1.699	1.00
392_Y	395_E	1.690	1.00
203_G	213_F	1.679	1.00
474_T	483_I	1.668	1.00
194_W	197_M	1.656	1.00
348_T	352_V	1.647	1.00
476_N	479_M	1.636	1.00
164_I	344_L	1.636	1.00
507_A	510_E	1.631	1.00
111_I	115_S	1.628	1.00
127_F	130_N	1.603	1.00
15_V	43_I	1.601	1.00
471_V	530_I	1.601	1.00
196_L	211_R	1.600	1.00
59_Q	291_M	1.587	1.00
198_I	210_G	1.586	1.00
412_M	526_L	1.583	1.00
348_T	377_A	1.581	1.00
330_K	338_I	1.576	1.00
145_V	381_S	1.576	1.00
163_I	333_Y	1.571	1.00
134_M	373_L	1.570	1.00
198_I	212_V	1.560	1.00
208_F	212_V	1.557	1.00
167_V	341_S	1.555	1.00
217_S	221_S	1.537	1.00
133_L	359_G	1.534	1.00
309_I	313_L	1.524	1.00
331_K	335_N	1.523	1.00
302_F	308_L	1.521	1.00
297_D	371_G	1.507	1.00
358_I	362_L	1.504	1.00
433_Y	436_N	1.493	1.00
358_I	361_Q	1.484	1.00
431_H	437_A	1.482	1.00
318_L	348_T	1.479	1.00
319_L	383_F	1.473	1.00
99_N	102_A	1.471	1.00
389_K	394_R	1.467	1.00
406_F	416_V	1.459	1.00
224_K	435_E	1.454	1.00
499_V	505_E	1.448	1.00
104_A	108_F	1.445	1.00
201_A	212_V	1.435	1.00
43_I	50_L	1.432	1.00
199_L	210_G	1.427	1.00
115_S	131_A	1.423	1.00
204_V	212_V	1.422	1.00
315_L	380_A	1.420	1.00
437_A	448_V	1.419	1.00
484_A	495_V	1.417	1.00
70_M	140_T	1.415	1.00
400_E	403_T	1.399	1.00
203_G	210_G	1.389	1.00
310_M	372_A	1.388	1.00
199_L	203_G	1.387	1.00
199_L	204_V	1.385	1.00
106_V	110_G	1.379	1.00
182_F	362_L	1.379	1.00
441_L	446_F	1.377	1.00
113_I	116_L	1.366	0.99
202_A	206_L	1.363	0.99
192_N	196_L	1.359	0.99
202_A	211_R	1.358	0.99
460_E	490_K	1.356	0.99
193_M	197_M	1.352	0.99
111_I	135_T	1.352	0.99
431_H	436_N	1.347	0.99
275_Q	455_E	1.341	0.99
263_V	272_L	1.331	0.99
219_V	237_L	1.329	0.99
217_S	220_Q	1.326	0.99
321_S	325_P	1.326	0.99
195_L	198_I	1.321	0.99
208_F	211_R	1.320	0.99
501_S	504_H	1.300	0.99
407_I	453_D	1.296	0.99
296_L	378_V	1.286	0.99
160_I	340_A	1.286	0.99
53_E	57_W	1.285	0.99
108_F	112_F	1.282	0.99
316_L	320_V	1.280	0.99
243_A	247_S	1.271	0.99
483_I	487_A	1.271	0.99
112_F	135_T	1.266	0.99
441_L	444_S	1.264	0.99
267_S	442_S	1.262	0.99
453_D	483_I	1.261	0.99
407_I	483_I	1.258	0.99
135_T	139_S	1.258	0.99
107_I	178_L	1.254	0.99
330_K	333_Y	1.250	0.99
517_S	523_K	1.238	0.99
201_A	211_R	1.235	0.99
207_Y	211_R	1.234	0.99
456_H	490_K	1.232	0.99
146_V	345_L	1.231	0.99
464_I	490_K	1.221	0.99
31_P	148_P	1.205	0.99
363_H	366_S	1.200	0.99
528_A	532_A	1.197	0.99
200_F	212_V	1.197	0.99
487_A	491_G	1.197	0.99
41_L	47_G	1.194	0.99
481_A	511_Q	1.194	0.99
481_A	507_A	1.192	0.99
38_I	42_I	1.190	0.99
92_P	329_L	1.189	0.99
311_I	372_A	1.186	0.99
160_I	337_T	1.184	0.99
150_L	161_G	1.181	0.99
193_M	211_R	1.176	0.98
485_L	489_D	1.166	0.98
519_L	523_K	1.164	0.98
106_V	326_V	1.159	0.98
477_E	480_N	1.154	0.98
392_Y	397_Q	1.154	0.98
463_G	466_E	1.152	0.98
410_N	413_T	1.152	0.98
191_G	194_W	1.150	0.98
409_A	417_T	1.149	0.98
506_A	510_E	1.149	0.98
100_T	104_A	1.147	0.98
197_M	201_A	1.137	0.98
405_T	470_L	1.135	0.98
517_S	521_S	1.132	0.98
141_I	171_A	1.128	0.98
406_F	471_V	1.127	0.98
202_A	212_V	1.126	0.98
315_L	319_L	1.126	0.98
525_L	529_L	1.123	0.98
178_L	355_A	1.121	0.98
168_A	351_L	1.119	0.98
86_K	92_P	1.116	0.98
196_L	199_L	1.108	0.98
436_N	439_E	1.102	0.98
518_I	523_K	1.098	0.98
7_A	10_V	1.094	0.98
357_T	361_Q	1.094	0.98
75_L	261_V	1.091	0.97
403_T	426_D	1.091	0.97
38_I	56_T	1.087	0.97
322_K	325_P	1.086	0.97
103_A	174_A	1.079	0.97
311_I	322_K	1.074	0.97
88_K	166_L	1.074	0.97
207_Y	213_F	1.073	0.97
196_L	200_F	1.073	0.97
175_T	355_A	1.069	0.97
140_T	178_L	1.067	0.97
310_M	314_L	1.066	0.97
481_A	504_H	1.065	0.97
242_V	252_N	1.065	0.97
524_T	531_E	1.064	0.97
115_S	128_I	1.053	0.97
529_L	532_A	1.052	0.97
200_F	203_G	1.051	0.97
34_V	382_I	1.048	0.97
104_A	107_I	1.047	0.97
310_M	313_L	1.047	0.97
105_S	109_V	1.044	0.97
80_S	84_K	1.044	0.97
102_A	106_V	1.041	0.97
146_V	344_L	1.035	0.97
12_V	20_P	1.035	0.97
99_N	103_A	1.025	0.96
103_A	170_I	1.023	0.96
308_L	311_I	1.018	0.96
141_I	345_L	1.011	0.96
191_G	196_L	1.009	0.96
133_L	137_I	1.008	0.96
42_I	47_G	1.007	0.96
44_G	51_V	1.004	0.96
363_H	367_T	1.003	0.96
527_R	531_E	1.002	0.96
481_A	485_L	1.000	0.96
130_N	366_S	0.999	0.96
523_K	530_I	0.997	0.96
10_V	243_A	0.996	0.96
155_I	388_F	0.994	0.96
523_K	527_R	0.994	0.96
233_A	237_L	0.993	0.96
500_G	518_I	0.992	0.96
434_Q	438_E	0.991	0.96
30_I	37_I	0.990	0.96
201_A	205_V	0.987	0.95
215_H	237_L	0.984	0.95
196_L	213_F	0.984	0.95
401_K	468_D	0.984	0.95
206_L	211_R	0.981	0.95
419_E	527_R	0.979	0.95
11_V	15_V	0.970	0.95
200_F	213_F	0.970	0.95
106_V	171_A	0.969	0.95
201_A	208_F	0.968	0.95
167_V	345_L	0.968	0.95
240_V	244_L	0.967	0.95
42_I	530_I	0.965	0.95
78_D	265_L	0.960	0.95
477_E	504_H	0.959	0.95
429_V	446_F	0.959	0.95
390_K	395_E	0.956	0.95
206_L	213_F	0.954	0.95
404_I	471_V	0.950	0.94
137_I	178_L	0.947	0.94
392_Y	396_E	0.945	0.94
404_I	469_I	0.945	0.94
413_T	431_H	0.942	0.94
393_K	397_Q	0.940	0.94
164_I	292_V	0.938	0.94
520_L	524_T	0.938	0.94
521_S	526_L	0.937	0.94
204_V	213_F	0.937	0.94
411_Q	498_S	0.936	0.94
197_M	200_F	0.935	0.94
480_N	511_Q	0.935	0.94
223_S	268_P	0.934	0.94
521_S	524_T	0.934	0.94
222_M	233_A	0.934	0.94
482_D	485_L	0.934	0.94
168_A	171_A	0.933	0.94
477_E	507_A	0.930	0.94
24_H	29_S	0.928	0.94
222_M	230_G	0.928	0.94
331_K	338_I	0.927	0.94
304_D	368_N	0.918	0.93
171_A	350_S	0.918	0.93
472_V	497_A	0.916	0.93
474_T	480_N	0.916	0.93
246_E	272_L	0.915	0.93
502_P	517_S	0.912	0.93
199_L	202_A	0.912	0.93
516_F	525_L	0.911	0.93
359_G	362_L	0.906	0.93
103_A	106_V	0.906	0.93
193_M	196_L	0.904	0.93
77_I	264_S	0.897	0.93
47_G	50_L	0.895	0.92
201_A	213_F	0.893	0.92
191_G	195_L	0.890	0.92
291_M	295_K	0.889	0.92
171_A	351_L	0.886	0.92
193_M	204_V	0.881	0.92
417_T	427_V	0.879	0.92
198_I	206_L	0.879	0.92
83_E	86_K	0.873	0.92
206_L	210_G	0.873	0.92
220_Q	224_K	0.872	0.91
117_L	186_Y	0.869	0.91
404_I	420_L	0.868	0.91
256_A	338_I	0.867	0.91
456_H	486_L	0.866	0.91
109_V	379_I	0.865	0.91
383_F	387_C	0.860	0.91
127_F	131_A	0.857	0.91
87_K	302_F	0.855	0.91
311_I	315_L	0.852	0.91
153_E	389_K	0.849	0.90
523_K	531_E	0.848	0.90
377_A	380_A	0.847	0.90
441_L	448_V	0.845	0.90
498_S	518_I	0.844	0.90
201_A	204_V	0.842	0.90
320_V	323_I	0.841	0.90
504_H	508_L	0.841	0.90
138_I	318_L	0.840	0.90
199_L	207_Y	0.840	0.90
517_S	524_T	0.839	0.90
108_F	113_I	0.835	0.90
10_V	236_T	0.830	0.89
199_L	206_L	0.829	0.89
471_V	496_I	0.828	0.89
409_A	429_V	0.825	0.89
413_T	473_A	0.824	0.89
365_I	369_M	0.824	0.89
344_L	388_F	0.823	0.89
479_M	482_D	0.823	0.89
76_E	144_G	0.822	0.89
146_V	168_A	0.818	0.89
111_I	128_I	0.818	0.89
10_V	239_I	0.816	0.89
416_V	471_V	0.816	0.89
25_R	29_S	0.816	0.89
515_I	526_L	0.816	0.89
379_I	383_F	0.813	0.88
232_R	283_F	0.812	0.88
356_A	365_I	0.805	0.88
196_L	206_L	0.803	0.88
409_A	446_F	0.802	0.88
513_I	517_S	0.802	0.88
496_I	530_I	0.800	0.88
205_V	213_F	0.800	0.88
228_Q	232_R	0.797	0.87
334_D	338_I	0.796	0.87
335_N	342_G	0.796	0.87
206_L	212_V	0.796	0.87
229_I	523_K	0.793	0.87
16_A	215_H	0.793	0.87
430_V	449_E	0.791	0.87
104_A	383_F	0.789	0.87
413_T	437_A	0.788	0.87
116_L	120_Y	0.785	0.87
143_L	350_S	0.785	0.87
319_L	322_K	0.785	0.87
85_G	88_K	0.785	0.87
45_K	294_V	0.784	0.86
332_W	335_N	0.783	0.86
141_I	144_G	0.782	0.86
174_A	329_L	0.781	0.86
389_K	395_E	0.777	0.86
475_G	518_I	0.776	0.86
112_F	132_F	0.775	0.86
303_Q	309_I	0.775	0.86
23_L	38_I	0.770	0.85
144_G	286_P	0.770	0.85
192_N	198_I	0.768	0.85
43_I	294_V	0.768	0.85
85_G	89_Q	0.767	0.85
511_Q	514_S	0.767	0.85
456_H	489_D	0.766	0.85
522_T	525_L	0.764	0.85
427_V	447_A	0.764	0.85
167_V	175_T	0.762	0.85
171_A	175_T	0.760	0.85
277_D	282_G	0.758	0.85
319_L	387_C	0.757	0.85
67_I	70_M	0.757	0.85
205_V	327_M	0.755	0.84
234_I	290_V	0.753	0.84
148_P	282_G	0.752	0.84
407_I	474_T	0.748	0.84
230_G	234_I	0.747	0.84
171_A	288_F	0.746	0.84
469_I	494_R	0.746	0.84
506_A	509_K	0.745	0.84
430_V	451_I	0.745	0.84
520_L	523_K	0.744	0.83
394_R	397_Q	0.744	0.83
205_V	490_K	0.744	0.83
39_M	266_L	0.743	0.83
140_T	175_T	0.740	0.83
421_P	427_V	0.738	0.83
430_V	462_L	0.738	0.83
232_R	282_G	0.737	0.83
74_G	293_G	0.736	0.83
231_T	254_L	0.735	0.83
36_E	44_G	0.733	0.83
369_M	372_A	0.733	0.83
65_G	255_G	0.733	0.83
28_L	454_Y	0.732	0.82
112_F	128_I	0.731	0.82
196_L	210_G	0.731	0.82
38_I	394_R	0.729	0.82
397_Q	489_D	0.728	0.82
505_E	515_I	0.726	0.82
77_I	294_V	0.726	0.82
321_S	328_Y	0.725	0.82
336_R	340_A	0.725	0.82
234_I	264_S	0.724	0.82
144_G	168_A	0.723	0.82
87_K	90_F	0.722	0.82
343_F	391_L	0.721	0.82
498_S	519_L	0.721	0.82
114_L	118_L	0.720	0.81
518_I	522_T	0.719	0.81
89_Q	170_I	0.718	0.81
36_E	286_P	0.718	0.81
133_L	182_F	0.717	0.81
500_G	517_S	0.716	0.81
38_I	481_A	0.716	0.81
102_A	351_L	0.716	0.81
326_V	329_L	0.713	0.81
411_Q	500_G	0.712	0.81
317_A	320_V	0.710	0.81
319_L	323_I	0.704	0.80
84_K	87_K	0.703	0.80
412_M	473_A	0.699	0.79
142_S	288_F	0.697	0.79
62_S	291_M	0.697	0.79
88_K	163_I	0.697	0.79
130_N	369_M	0.697	0.79
413_T	453_D	0.695	0.79
204_V	262_L	0.695	0.79
468_D	494_R	0.694	0.79
370_S	374_I	0.693	0.79
110_G	138_I	0.693	0.79
421_P	446_F	0.692	0.79
518_I	524_T	0.692	0.79
20_P	286_P	0.692	0.79
155_I	340_A	0.692	0.79
404_I	425_Y	0.691	0.79
417_T	429_V	0.690	0.79
314_L	317_A	0.690	0.79
25_R	28_L	0.689	0.79
176_M	253_I	0.688	0.78
367_T	401_K	0.688	0.78
433_Y	448_V	0.688	0.78
436_N	441_L	0.686	0.78
439_E	443_E	0.686	0.78
381_S	384_T	0.684	0.78
323_I	343_F	0.682	0.78
131_A	342_G	0.682	0.78
525_L	528_A	0.681	0.78
417_T	441_L	0.680	0.78
484_A	497_A	0.680	0.78
359_G	363_H	0.679	0.78
192_N	195_L	0.676	0.77
128_I	131_A	0.674	0.77
111_I	114_L	0.673	0.77
194_W	200_F	0.673	0.77
73_S	143_L	0.673	0.77
134_M	138_I	0.671	0.77
142_S	347_S	0.668	0.76
311_I	321_S	0.668	0.76
496_I	526_L	0.664	0.76
28_L	269_N	0.664	0.76
230_G	268_P	0.664	0.76
321_S	324_I	0.664	0.76
304_D	310_M	0.663	0.76
365_I	373_L	0.663	0.76
312_P	315_L	0.663	0.76
53_E	56_T	0.663	0.76
273_V	286_P	0.661	0.76
107_I	111_I	0.660	0.76
198_I	205_V	0.660	0.76
137_I	365_I	0.660	0.76
197_M	208_F	0.660	0.76
160_I	341_S	0.657	0.75
411_Q	475_G	0.656	0.75
428_R	464_I	0.656	0.75
234_I	238_I	0.655	0.75
109_V	321_S	0.654	0.75
6_V	243_A	0.653	0.75
73_S	77_I	0.653	0.75
11_V	43_I	0.653	0.75
49_N	62_S	0.652	0.75
187_G	190_S	0.651	0.75
204_V	258_L	0.650	0.74
296_L	375_L	0.649	0.74
271_E	274_Q	0.645	0.74
241_L	262_L	0.644	0.74
232_R	284_L	0.644	0.74
314_L	372_A	0.643	0.74
189_D	202_A	0.643	0.74
143_L	351_L	0.642	0.73
304_D	308_L	0.642	0.73
333_Y	337_T	0.641	0.73
115_S	120_Y	0.640	0.73
109_V	114_L	0.639	0.73
318_L	380_A	0.637	0.73
68_F	179_L	0.637	0.73
175_T	179_L	0.637	0.73
288_F	293_G	0.637	0.73
120_Y	134_M	0.636	0.73
138_I	411_Q	0.635	0.73
405_T	463_G	0.634	0.73
145_V	429_V	0.634	0.73
136_L	181_V	0.633	0.72
410_N	473_A	0.633	0.72
252_N	287_I	0.633	0.72
338_I	342_G	0.632	0.72
15_V	22_L	0.632	0.72
34_V	359_G	0.631	0.72
204_V	209_F	0.630	0.72
272_L	284_L	0.630	0.72
308_L	313_L	0.630	0.72
143_L	168_A	0.629	0.72
140_T	144_G	0.629	0.72
233_A	238_I	0.625	0.72
324_I	503_E	0.625	0.72
111_I	132_F	0.624	0.71
10_V	258_L	0.622	0.71
202_A	303_Q	0.621	0.71
176_M	354_A	0.620	0.71
168_A	350_S	0.620	0.71
65_G	257_F	0.620	0.71
470_L	483_I	0.619	0.71
323_I	342_G	0.619	0.71
219_V	233_A	0.619	0.71
206_L	262_L	0.618	0.71
218_F	221_S	0.617	0.71
476_N	481_A	0.617	0.71
308_L	312_P	0.616	0.70
197_M	213_F	0.615	0.70
197_M	316_L	0.614	0.70
297_D	300_T	0.613	0.70
193_M	208_F	0.613	0.70
230_G	233_A	0.612	0.70
204_V	208_F	0.611	0.70
85_G	92_P	0.611	0.70
216_R	266_L	0.610	0.70
326_V	341_S	0.609	0.70
437_A	450_T	0.607	0.69
14_I	18_L	0.607	0.69
527_R	530_I	0.607	0.69
144_G	175_T	0.606	0.69
198_I	201_A	0.606	0.69
92_P	102_A	0.606	0.69
502_P	505_E	0.605	0.69
116_L	379_I	0.604	0.69
193_M	213_F	0.604	0.69
69_L	341_S	0.604	0.69
311_I	314_L	0.603	0.69
117_L	443_E	0.602	0.69
104_A	468_D	0.601	0.69
403_T	467_T	0.601	0.69
32_V	89_Q	0.600	0.68
131_A	366_S	0.600	0.68
526_L	530_I	0.600	0.68
119_S	127_F	0.599	0.68
495_V	513_I	0.599	0.68
65_G	288_F	0.599	0.68
106_V	109_V	0.598	0.68
497_A	511_Q	0.596	0.68
513_I	526_L	0.595	0.68
304_D	324_I	0.593	0.68
90_F	102_A	0.592	0.67
435_E	439_E	0.592	0.67
276_L	279_F	0.591	0.67
421_P	444_S	0.591	0.67
200_F	207_Y	0.589	0.67
191_G	204_V	0.588	0.67
223_S	230_G	0.588	0.67
89_Q	102_A	0.587	0.67
319_L	346_T	0.587	0.67
14_I	240_V	0.586	0.67
439_E	444_S	0.586	0.67
404_I	530_I	0.586	0.67
220_Q	267_S	0.585	0.66
75_L	133_L	0.583	0.66
299_W	303_Q	0.583	0.66
67_I	252_N	0.582	0.66
414_L	444_S	0.582	0.66
313_L	320_V	0.582	0.66
377_A	384_T	0.582	0.66
138_I	373_L	0.581	0.66
398_P	401_K	0.581	0.66
411_Q	414_L	0.581	0.66
89_Q	92_P	0.581	0.66
254_L	284_L	0.580	0.66
116_L	510_E	0.580	0.66
106_V	325_P	0.579	0.66
334_D	337_T	0.578	0.66
398_P	464_I	0.577	0.65
77_I	138_I	0.576	0.65
110_G	113_I	0.576	0.65
486_L	515_I	0.576	0.65
193_M	201_A	0.576	0.65
23_L	35_A	0.575	0.65
218_F	271_E	0.574	0.65
9_L	61_L	0.574	0.65
373_L	386_I	0.574	0.65
384_T	388_F	0.573	0.65
130_N	324_I	0.573	0.65
116_L	128_I	0.573	0.65
251_E	257_F	0.572	0.65
181_V	315_L	0.572	0.65
517_S	528_A	0.572	0.65
77_I	147_V	0.571	0.65
524_T	529_L	0.570	0.64
200_F	206_L	0.569	0.64
309_I	489_D	0.568	0.64
117_L	316_L	0.568	0.64
108_F	111_I	0.568	0.64
473_A	520_L	0.568	0.64
208_F	213_F	0.568	0.64
150_L	164_I	0.568	0.64
226_T	239_I	0.566	0.64
324_I	327_M	0.564	0.64
86_K	524_T	0.563	0.64
198_I	204_V	0.563	0.64
382_I	386_I	0.562	0.63
145_V	388_F	0.562	0.63
411_Q	519_L	0.562	0.63
31_P	137_I	0.559	0.63
401_K	426_D	0.559	0.63
349_L	353_I	0.558	0.63
438_E	442_S	0.557	0.63
465_F	493_E	0.557	0.63
37_I	43_I	0.557	0.63
77_I	295_K	0.557	0.63
149_T	263_V	0.557	0.63
456_H	460_E	0.556	0.63
146_V	317_A	0.555	0.62
360_Q	365_I	0.555	0.62
511_Q	516_F	0.554	0.62
83_E	496_I	0.552	0.62
181_V	301_L	0.551	0.62
108_F	218_F	0.551	0.62
146_V	347_S	0.550	0.62
169_V	287_I	0.550	0.62
322_K	345_L	0.549	0.62
192_N	211_R	0.548	0.61
405_T	447_A	0.547	0.61
52_V	58_L	0.547	0.61
145_V	285_I	0.547	0.61
113_I	313_L	0.546	0.61
131_A	194_W	0.546	0.61
434_Q	437_A	0.545	0.61
205_V	211_R	0.544	0.61
227_I	275_Q	0.542	0.61
213_F	217_S	0.542	0.61
143_L	253_I	0.542	0.61
405_T	428_R	0.542	0.61
405_T	416_V	0.542	0.61
69_L	143_L	0.542	0.61
90_F	100_T	0.542	0.61
164_I	345_L	0.541	0.60
176_M	347_S	0.539	0.60
116_L	119_S	0.539	0.60
63_M	143_L	0.539	0.60
477_E	484_A	0.539	0.60
150_L	155_I	0.538	0.60
431_H	452_S	0.537	0.60
11_V	312_P	0.537	0.60
472_V	513_I	0.536	0.60
138_I	348_T	0.536	0.60
32_V	342_G	0.536	0.60
228_Q	239_I	0.535	0.60
497_A	513_I	0.535	0.60
144_G	381_S	0.535	0.60
312_P	321_S	0.535	0.60
143_L	171_A	0.534	0.60
438_E	485_L	0.534	0.60
367_T	371_G	0.534	0.60
77_I	271_E	0.533	0.59
141_I	350_S	0.532	0.59
55_D	428_R	0.532	0.59
21_I	232_R	0.530	0.59
520_L	525_L	0.530	0.59
128_I	132_F	0.529	0.59
73_S	140_T	0.527	0.59
453_D	474_T	0.526	0.58
450_T	499_V	0.525	0.58
144_G	354_A	0.525	0.58
237_L	241_L	0.525	0.58
148_P	152_E	0.525	0.58
356_A	377_A	0.525	0.58
11_V	50_L	0.524	0.58
382_I	385_P	0.523	0.58
456_H	491_G	0.523	0.58
415_P	520_L	0.523	0.58
134_M	318_L	0.522	0.58
114_L	131_A	0.522	0.58
497_A	508_L	0.521	0.58
33_V	140_T	0.521	0.58
517_S	522_T	0.521	0.58
342_G	391_L	0.520	0.58
196_L	207_Y	0.520	0.58
133_L	167_V	0.517	0.57
118_L	310_M	0.517	0.57
507_A	511_Q	0.516	0.57
300_T	316_L	0.516	0.57
43_I	127_F	0.516	0.57
203_G	206_L	0.515	0.57
23_L	34_V	0.515	0.57
406_F	523_K	0.514	0.57
110_G	397_Q	0.514	0.57
196_L	212_V	0.514	0.57
255_G	288_F	0.513	0.56
304_D	366_S	0.512	0.56
192_N	197_M	0.511	0.56
330_K	341_S	0.511	0.56
90_F	99_N	0.511	0.56
19_T	39_M	0.511	0.56
20_P	32_V	0.509	0.56
116_L	324_I	0.509	0.56
430_V	458_T	0.508	0.56
419_E	520_L	0.507	0.56
42_I	304_D	0.505	0.55
398_P	466_E	0.505	0.55
525_L	531_E	0.505	0.55
193_M	212_V	0.504	0.55
323_I	330_K	0.503	0.55
72_L	229_I	0.503	0.55
69_L	171_A	0.502	0.55
418_L	473_A	0.501	0.55
76_E	168_A	0.501	0.55
234_I	272_L	0.501	0.55
61_L	419_E	0.500	0.55
222_M	268_P	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bwzA	2	0.6156	100	0.607	Contact Map
4cz8A	2	0.614	100	0.636	Contact Map
4czbA	2	0.6189	100	0.643	Contact Map
1lnqA	6	0.4658	100	0.738	Contact Map
4gx0A	3	0.4967	100	0.743	Contact Map
2aefA	2	0.3404	100	0.757	Contact Map
3l4bC	2	0.3453	100	0.779	Contact Map
3mt5A	5	0.3355	100	0.782	Contact Map
3nafA	3	0.3583	100	0.782	Contact Map
4g65A	2	0.3485	100	0.786	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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