GREMLIN Database
YJBH - UPF0413 protein YjbH
UniProt: O31606 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 299 (268)
Sequences: 269 (223)
Seq/√Len: 13.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
249_I260_V5.3761.00
173_L177_M4.1931.00
21_L218_L4.0921.00
109_L173_L3.5290.99
237_F244_V3.3200.98
129_M146_L3.3140.98
117_Q163_D3.0950.98
99_Q142_D2.8050.96
79_E88_S2.7660.95
249_I264_M2.6640.94
62_L139_N2.6430.94
247_K251_L2.6320.94
261_E275_K2.6230.94
250_A260_V2.5280.92
22_E55_R2.3390.89
245_A283_F2.3370.89
38_E130_Q2.3150.88
26_F180_A2.2280.86
24_Y202_G2.1960.86
222_L226_P2.1840.85
94_W100_P2.1370.84
72_H238_I2.0650.82
78_W87_M1.9800.79
18_K221_M1.9470.78
260_V264_M1.9260.77
89_C104_P1.9060.76
112_K115_E1.9060.76
59_S188_N1.9030.76
276_V285_K1.8520.74
250_A256_S1.8320.73
108_A134_F1.8200.73
96_E137_K1.7700.70
36_S82_A1.7680.70
27_V80_K1.7330.69
18_K148_E1.7310.69
26_F183_M1.7230.68
243_F276_V1.7040.67
130_Q179_I1.6850.66
110_A150_A1.6830.66
47_R135_V1.6650.65
72_H124_Q1.6530.65
87_M90_D1.6420.64
132_S154_S1.6150.63
80_K246_S1.6080.63
117_Q211_Y1.5790.61
34_C134_F1.5750.61
246_S260_V1.5650.60
47_R211_Y1.5570.60
188_N280_H1.5560.60
15_G158_E1.5400.59
238_I264_M1.5110.58
232_P253_Y1.5100.58
27_V61_S1.4950.57
112_K176_D1.4840.56
185_V195_N1.4800.56
75_A91_G1.4620.55
114_A155_L1.4580.55
78_W100_P1.4490.54
80_K106_M1.4380.54
231_T270_A1.4360.54
193_F261_E1.4120.52
135_V279_K1.3970.52
74_L177_M1.3730.50
181_A221_M1.3710.50
223_G276_V1.3690.50
94_W137_K1.3600.50
103_S233_P1.3600.50
58_A173_L1.3520.49
118_G122_G1.3430.49
183_M195_N1.3380.48
110_A160_F1.3320.48
116_L193_F1.3270.48
74_L77_A1.3250.48
118_G126_L1.3140.47
24_Y183_M1.3120.47
50_R129_M1.3090.47
36_S62_L1.3050.47
278_A283_F1.2660.45
54_L228_P1.2280.43
109_L196_T1.2220.42
196_T221_M1.2160.42
78_W90_D1.1920.41
81_I134_F1.1880.41
124_Q155_L1.1850.40
110_A164_L1.1840.40
171_K175_C1.1790.40
67_K73_L1.1740.40
43_K267_L1.1690.40
178_K274_A1.1650.39
32_P62_L1.1580.39
191_L205_V1.1540.39
151_E157_L1.1530.39
109_L177_M1.1500.39
52_F218_L1.1380.38
117_Q155_L1.1290.38
252_V283_F1.1270.37
62_L195_N1.1250.37
137_K279_K1.1170.37
84_R244_V1.1160.37
77_A111_F1.1160.37
263_E266_K1.1110.37
210_S274_A1.1110.37
27_V106_M1.1030.36
32_P82_A1.0960.36
166_S269_F1.0950.36
75_A88_S1.0930.36
79_E93_V1.0920.36
158_E258_E1.0890.36
163_D211_Y1.0850.35
194_F204_K1.0780.35
99_Q139_N1.0770.35
78_W91_G1.0690.35
166_S271_K1.0560.34
134_F214_Y1.0440.33
17_P212_D1.0440.33
62_L65_L1.0410.33
127_R207_G1.0370.33
45_K217_I1.0280.33
152_N190_T1.0250.32
88_S188_N1.0230.32
48_Y252_V1.0230.32
87_M91_G1.0200.32
144_N161_K1.0180.32
127_R131_E1.0160.32
27_V104_P1.0160.32
143_E173_L1.0110.32
22_E117_Q1.0110.32
85_S208_S1.0080.32
226_P229_S1.0080.32
190_T210_S1.0040.31
59_S130_Q1.0030.31
133_L173_L1.0010.31
282_M285_K1.0000.31
233_P253_Y1.0000.31
35_W131_E0.9970.31
27_V122_G0.9960.31
85_S203_L0.9950.31
57_I179_I0.9930.31
120_K130_Q0.9910.31
125_F142_D0.9790.30
95_F221_M0.9740.30
32_P140_I0.9690.30
29_P39_P0.9680.30
199_E218_L0.9660.30
50_R178_K0.9640.30
75_A96_E0.9640.30
35_W94_W0.9570.29
87_M245_A0.9500.29
89_C279_K0.9450.29
60_A78_W0.9440.29
148_E152_N0.9390.29
87_M251_L0.9370.28
183_M202_G0.9370.28
246_S250_A0.9360.28
85_S89_C0.9350.28
51_F254_D0.9270.28
236_C265_K0.9150.28
53_T272_K0.9120.27
22_E172_A0.9090.27
92_N231_T0.9090.27
132_S162_K0.9090.27
137_K281_G0.9060.27
195_N199_E0.9050.27
31_C127_R0.9040.27
162_K212_D0.9040.27
114_A267_L0.9040.27
92_N137_K0.9030.27
18_K83_S0.8970.27
86_G200_D0.8960.27
149_I153_T0.8930.27
31_C34_C0.8910.27
35_W65_L0.8910.27
26_F209_Y0.8870.26
168_S233_P0.8860.26
75_A103_S0.8830.26
112_K163_D0.8800.26
125_F146_L0.8800.26
62_L140_I0.8750.26
119_R233_P0.8740.26
274_A285_K0.8720.26
135_V251_L0.8690.26
133_L140_I0.8680.26
245_A281_G0.8660.25
238_I249_I0.8650.25
276_V284_W0.8650.25
28_D189_P0.8650.25
52_F202_G0.8640.25
22_E118_G0.8630.25
202_G232_P0.8590.25
194_F202_G0.8590.25
162_K276_V0.8590.25
25_M206_P0.8560.25
90_D251_L0.8540.25
100_P139_N0.8540.25
95_F264_M0.8490.25
81_I89_C0.8410.24
85_S260_V0.8410.24
78_W188_N0.8330.24
63_T205_V0.8310.24
144_N228_P0.8270.24
148_E203_L0.8240.24
21_L158_E0.8240.24
178_K182_E0.8240.24
62_L100_P0.8220.24
149_I180_A0.8210.24
35_W78_W0.8150.23
163_D284_W0.8130.23
70_K73_L0.8100.23
142_D240_Y0.8090.23
61_S106_M0.8050.23
39_P87_M0.8040.23
54_L213_V0.8040.23
183_M194_F0.8000.23
259_E276_V0.7980.23
65_L130_Q0.7970.23
30_L38_E0.7870.22
187_V201_E0.7860.22
55_R139_N0.7820.22
18_K196_T0.7810.22
245_A252_V0.7810.22
277_E283_F0.7800.22
136_S152_N0.7730.22
257_L275_K0.7720.22
119_R255_L0.7710.22
21_L76_E0.7700.22
32_P81_I0.7690.22
102_S126_L0.7660.22
27_V153_T0.7620.21
85_S255_L0.7620.21
70_K78_W0.7620.21
245_A278_A0.7610.21
96_E279_K0.7610.21
73_L187_V0.7600.21
24_Y204_K0.7590.21
147_L164_L0.7440.21
74_L109_L0.7430.21
93_V247_K0.7420.21
26_F276_V0.7420.21
26_F113_A0.7420.21
125_F174_Q0.7410.21
104_P279_K0.7360.21
113_A284_W0.7330.20
175_C182_E0.7330.20
110_A172_A0.7320.20
71_K78_W0.7300.20
120_K178_K0.7290.20
129_M282_M0.7290.20
40_V155_L0.7280.20
80_K188_N0.7270.20
264_M284_W0.7260.20
110_A114_A0.7250.20
144_N162_K0.7240.20
71_K164_L0.7230.20
54_L272_K0.7200.20
26_F174_Q0.7190.20
144_N223_G0.7190.20
206_P246_S0.7170.20
88_S104_P0.7160.20
54_L123_M0.7150.20
75_A94_W0.7110.20
41_I54_L0.7100.20
74_L187_V0.7070.20
163_D166_S0.7060.20
116_L150_A0.7060.20
130_Q253_Y0.7040.19
160_F183_M0.7030.19
150_A160_F0.7020.19
160_F180_A0.7000.19
162_K228_P0.7000.19
52_F272_K0.7000.19
81_I88_S0.6970.19
260_V282_M0.6960.19
23_I148_E0.6960.19
104_P107_A0.6880.19
60_A71_K0.6870.19
75_A79_E0.6850.19
179_I241_F0.6840.19
81_I188_N0.6830.19
148_E221_M0.6820.19
18_K242_R0.6770.19
106_M250_A0.6740.18
261_E274_A0.6740.18
218_L254_D0.6730.18
64_A77_A0.6730.18
48_Y127_R0.6720.18
219_F227_K0.6710.18
204_K232_P0.6690.18
61_S104_P0.6630.18
236_C239_E0.6610.18
24_Y194_F0.6600.18
32_P65_L0.6550.18
143_E161_K0.6530.18
32_P37_L0.6520.18
80_K122_G0.6490.18
175_C178_K0.6480.18
37_L65_L0.6460.18
178_K265_K0.6450.18
21_L223_G0.6410.17
136_S245_A0.6410.17
155_L218_L0.6390.17
157_L160_F0.6380.17
155_L163_D0.6370.17
25_M100_P0.6360.17
87_M94_W0.6350.17
162_K256_S0.6340.17
15_G138_K0.6330.17
17_P167_Q0.6310.17
114_A163_D0.6300.17
61_S88_S0.6280.17
75_A153_T0.6280.17
56_I173_L0.6280.17
259_E270_A0.6270.17
31_C38_E0.6230.17
22_E115_E0.6210.17
32_P188_N0.6120.17
113_A129_M0.6100.16
148_E196_T0.6090.16
94_W281_G0.6070.16
33_E279_K0.6050.16
25_M139_N0.6040.16
16_H231_T0.6030.16
93_V205_V0.6020.16
147_L161_K0.6000.16
237_F253_Y0.5980.16
26_F253_Y0.5960.16
133_L185_V0.5950.16
27_V130_Q0.5940.16
96_E99_Q0.5940.16
69_R181_A0.5910.16
52_F254_D0.5880.16
218_L232_P0.5830.16
181_A260_V0.5820.16
212_D224_D0.5820.16
71_K77_A0.5810.16
42_K252_V0.5810.16
139_N161_K0.5800.16
164_L276_V0.5800.16
107_A260_V0.5780.16
219_F225_E0.5780.16
73_L77_A0.5760.16
202_G265_K0.5750.15
113_A169_A0.5750.15
31_C134_F0.5740.15
162_K231_T0.5710.15
76_E167_Q0.5680.15
51_F222_L0.5680.15
31_C131_E0.5650.15
41_I67_K0.5650.15
145_V260_V0.5650.15
89_C244_V0.5650.15
74_L78_W0.5640.15
195_N222_L0.5640.15
104_P209_Y0.5630.15
142_D285_K0.5620.15
82_A91_G0.5580.15
46_I121_A0.5550.15
26_F116_L0.5550.15
204_K265_K0.5550.15
60_A103_S0.5530.15
255_L260_V0.5520.15
45_K227_K0.5520.15
25_M59_S0.5520.15
146_L232_P0.5510.15
146_L180_A0.5480.15
238_I273_V0.5470.15
118_G163_D0.5470.15
114_A117_Q0.5460.15
122_G165_H0.5450.15
24_Y160_F0.5450.15
71_K99_Q0.5450.15
34_C112_K0.5430.15
103_S230_E0.5420.15
81_I84_R0.5400.15
148_E168_S0.5370.14
112_K204_K0.5360.14
61_S280_H0.5360.14
133_L285_K0.5300.14
131_E163_D0.5300.14
261_E284_W0.5300.14
71_K217_I0.5290.14
36_S75_A0.5290.14
256_S265_K0.5280.14
61_S268_A0.5280.14
49_G60_A0.5270.14
59_S264_M0.5230.14
63_T280_H0.5200.14
153_T239_E0.5160.14
168_S230_E0.5160.14
173_L203_L0.5140.14
160_F273_V0.5130.14
45_K61_S0.5100.14
17_P106_M0.5080.14
24_Y54_L0.5070.14
86_G244_V0.5070.14
62_L66_N0.5070.14
93_V215_E0.5050.14
179_I191_L0.5040.14
78_W99_Q0.5030.14
78_W88_S0.5020.14
109_L236_C0.5010.14
275_K282_M0.5010.14
237_F252_V0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2in3A 1 0.6689 100 0.69 Contact Map
3kzqA 3 0.6789 100 0.697 Contact Map
3rppA 2 0.6923 100 0.709 Contact Map
1r4wA 2 0.7057 100 0.715 Contact Map
3fz5A 2 0.6321 100 0.725 Contact Map
3gl5A 2 0.7124 100 0.731 Contact Map
2imfA 2 0.6488 100 0.738 Contact Map
3ghaA 1 0.5753 99.9 0.774 Contact Map
3hz8A 1 0.6254 99.9 0.777 Contact Map
4p3yB 1 0.592 99.9 0.779 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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