PEPF - BACSU - GREMLIN Contacts

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PEPF - Oligoendopeptidase F homolog

UniProt:	O31605	Sequences: MKGTKGKVFRVFTAFLAFVLFITAYDLTKGSEKPEDIHNTSLLRNSCFFNWLESKKTRGITMAEEKKANQLPDRSEVKAEDTWRLEDIFPSDEAWNKEFQAVKELIPNLSKYKGKLADSADHLYEALTYQDKVMERLGRLYTYAHMRSDQDTGNSFYQGLNDKAGNLYTQAASATAYLVPEILSIEEDKLQQFILEKEELKLYSHAIEEITKERPHVLSEKEEALLAEASEVLGSSSNTFSVLNNADITFPSIKDEDGNEKQITHGNFINFLESENREVRKNAFDAVYKTYGQYKNTMATTLSGTVKKDNFYARVKKYKSAREAALSNNSIPEEVYDNLVKTINKHLPLLHRYIALRKKVLELDEVHIYDLYTPLVKDAGMKVTYEEAKDYMLKGLAPLGEEYASILKEGLENRWVDVYENKGKRNGAYSSGAYGTNPYILMNWHNNVNNLFTLVHEFGHSVHSYYTRKHQPYPYGNYSIFVAEVASTTNEALLGEYLLNNLEDEKQRLYILNHMLEGFRGTVFRQTMFAEFEHLIHTKAQEGEPLTPELLTNVYYDLNKKYFGDGMVIDKEIGLEWSRIPHFYYNYYVYQYATGYSAAQALSSQILKEGKPAVDRYIDFLKAGSSQYPIDVLKKAGVDMTSPEPIEAACKMFEEKLDEMEELLMKVKQS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	670 (553)
Sequences:	6285 (4310)
Seq/√Len:	183.3

ECOLI - DCP OPDA
BACSU - PEPF
HALSA - Q9HNP8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
281_K	285_D	7.073	1.00
221_K	304_G	5.842	1.00
319_K	323_E	5.369	1.00
634_K	639_D	5.043	1.00
214_R	311_F	4.720	1.00
627_Q	635_K	3.846	1.00
627_Q	631_D	3.791	1.00
320_S	323_E	3.576	1.00
251_P	275_E	3.568	1.00
605_Q	616_R	3.481	1.00
275_E	373_T	3.443	1.00
278_E	281_K	3.329	1.00
96_N	163_K	3.285	1.00
208_E	211_T	3.179	1.00
550_L	553_N	3.080	1.00
89_F	98_E	3.044	1.00
103_K	170_Q	3.036	1.00
97_K	101_A	3.021	1.00
553_N	557_D	3.009	1.00
344_N	561_K	2.909	1.00
616_R	619_D	2.876	1.00
408_K	465_Y	2.767	1.00
619_D	635_K	2.757	1.00
310_N	314_R	2.746	1.00
300_T	304_G	2.660	1.00
323_E	333_E	2.649	1.00
97_K	100_Q	2.601	1.00
557_D	561_K	2.535	1.00
182_I	185_I	2.489	1.00
249_T	276_N	2.449	1.00
219_S	222_E	2.410	1.00
100_Q	104_E	2.381	1.00
556_Y	560_K	2.358	1.00
278_E	282_N	2.334	1.00
611_K	615_D	2.300	1.00
355_A	358_K	2.266	1.00
96_N	100_Q	2.266	1.00
393_L	408_K	2.255	1.00
241_S	244_N	2.216	1.00
318_Y	327_S	2.178	1.00
539_K	550_L	2.149	1.00
186_E	189_K	2.148	1.00
627_Q	632_V	2.133	1.00
101_A	136_R	2.063	1.00
605_Q	609_E	2.021	1.00
275_E	377_K	1.998	1.00
98_E	136_R	1.998	1.00
107_P	111_K	1.991	1.00
252_S	260_E	1.985	1.00
90_P	94_A	1.977	1.00
124_Y	128_T	1.968	1.00
440_I	461_S	1.966	1.00
358_K	361_L	1.960	1.00
535_L	539_K	1.959	1.00
390_D	394_K	1.912	1.00
218_L	308_K	1.910	1.00
535_L	557_D	1.896	1.00
623_A	632_V	1.894	1.00
384_T	387_E	1.864	1.00
334_E	338_N	1.859	1.00
356_L	382_K	1.859	1.00
281_K	369_Y	1.843	1.00
149_D	429_Y	1.843	1.00
341_K	345_K	1.839	1.00
554_V	557_D	1.839	1.00
509_L	513_N	1.834	1.00
92_D	96_N	1.819	1.00
384_T	444_W	1.813	1.00
84_R	387_E	1.808	1.00
190_L	194_I	1.803	1.00
155_S	159_G	1.800	1.00
337_D	534_H	1.783	1.00
631_D	635_K	1.776	1.00
346_H	647_E	1.764	1.00
402_E	405_S	1.757	1.00
609_E	612_P	1.748	1.00
535_L	554_V	1.744	1.00
216_H	317_K	1.742	1.00
92_D	163_K	1.721	1.00
103_K	107_P	1.718	1.00
222_E	305_T	1.703	1.00
100_Q	103_K	1.694	1.00
225_L	315_V	1.693	1.00
525_R	529_F	1.676	1.00
302_L	536_I	1.672	1.00
292_G	295_K	1.671	1.00
623_A	627_Q	1.663	1.00
295_K	552_T	1.640	1.00
349_L	352_R	1.634	1.00
604_S	608_K	1.633	1.00
535_L	538_T	1.618	1.00
105_L	108_N	1.604	1.00
557_D	560_K	1.602	1.00
430_S	464_S	1.602	1.00
98_E	140_L	1.601	1.00
240_F	244_N	1.583	1.00
394_K	501_N	1.575	1.00
239_T	244_N	1.569	1.00
82_T	85_L	1.562	1.00
274_S	279_V	1.561	1.00
448_V	495_G	1.547	1.00
84_R	87_D	1.539	1.00
159_G	163_K	1.536	1.00
388_A	393_L	1.530	1.00
108_N	129_Y	1.529	1.00
119_S	122_H	1.522	1.00
552_T	577_W	1.517	1.00
214_R	217_V	1.514	1.00
496_E	607_L	1.512	1.00
337_D	341_K	1.510	1.00
631_D	634_K	1.508	1.00
98_E	101_A	1.508	1.00
277_R	367_H	1.506	1.00
338_N	342_T	1.500	1.00
105_L	136_R	1.497	1.00
351_H	355_A	1.491	1.00
175_T	179_V	1.490	1.00
221_K	224_A	1.489	1.00
201_K	204_S	1.486	1.00
612_P	615_D	1.483	1.00
347_L	523_V	1.481	1.00
79_A	82_T	1.476	1.00
392_M	455_V	1.475	1.00
272_L	283_A	1.471	1.00
277_R	363_L	1.467	1.00
365_E	568_V	1.461	1.00
320_S	538_T	1.450	1.00
612_P	616_R	1.446	1.00
332_P	335_V	1.441	1.00
108_N	111_K	1.430	1.00
628_Y	631_D	1.429	1.00
609_E	613_A	1.420	1.00
268_F	283_A	1.416	1.00
101_A	105_L	1.414	1.00
231_E	298_M	1.413	1.00
604_S	607_L	1.404	1.00
312_Y	321_A	1.398	1.00
314_R	541_Q	1.396	1.00
135_E	435_G	1.391	1.00
277_R	369_Y	1.385	1.00
310_N	541_Q	1.373	1.00
94_A	97_K	1.372	1.00
204_S	208_E	1.371	1.00
255_D	259_N	1.371	1.00
212_K	330_S	1.371	1.00
249_T	262_Q	1.366	1.00
342_T	346_H	1.362	1.00
182_I	186_E	1.353	1.00
191_Q	195_L	1.344	1.00
104_E	107_P	1.339	1.00
201_K	206_A	1.339	1.00
325_A	329_N	1.339	1.00
187_E	191_Q	1.334	1.00
397_A	404_A	1.334	1.00
107_P	110_S	1.332	1.00
393_L	415_W	1.332	1.00
236_S	239_T	1.328	1.00
341_K	561_K	1.325	1.00
87_D	90_P	1.323	1.00
556_Y	574_G	1.318	1.00
329_N	591_Q	1.318	1.00
213_E	217_V	1.317	1.00
485_V	602_L	1.316	1.00
254_K	260_E	1.316	1.00
642_S	645_P	1.309	1.00
401_E	405_S	1.301	1.00
218_L	222_E	1.294	1.00
224_A	228_E	1.286	1.00
445_H	450_N	1.284	1.00
286_A	289_K	1.274	1.00
91_S	94_A	1.274	1.00
87_D	437_N	1.273	1.00
122_H	125_E	1.270	1.00
644_E	648_A	1.254	1.00
326_L	329_N	1.251	1.00
394_K	397_A	1.246	1.00
400_G	405_S	1.242	1.00
549_E	553_N	1.236	1.00
222_E	225_L	1.234	1.00
261_K	283_A	1.226	1.00
282_N	286_A	1.213	1.00
263_I	286_A	1.211	1.00
504_D	507_Q	1.199	1.00
320_S	333_E	1.195	1.00
343_I	527_T	1.191	1.00
358_K	364_D	1.191	1.00
304_G	307_K	1.190	1.00
148_S	161_N	1.186	1.00
159_G	162_D	1.186	1.00
447_N	450_N	1.177	1.00
95_W	140_L	1.177	1.00
345_K	647_E	1.171	1.00
178_L	181_E	1.168	1.00
93_E	97_K	1.165	1.00
302_L	551_L	1.165	1.00
189_K	471_Q	1.155	1.00
211_T	214_R	1.154	1.00
345_K	643_P	1.151	1.00
104_E	108_N	1.150	1.00
535_L	561_K	1.150	1.00
249_T	282_N	1.148	1.00
202_L	327_S	1.145	1.00
406_I	409_E	1.143	1.00
99_F	167_L	1.141	1.00
268_F	272_L	1.137	1.00
197_K	201_K	1.134	1.00
102_V	171_A	1.134	1.00
302_L	577_W	1.123	1.00
285_D	572_E	1.121	1.00
268_F	287_V	1.118	1.00
529_F	583_F	1.118	1.00
534_H	587_Y	1.116	1.00
192_Q	474_P	1.114	1.00
86_E	90_P	1.114	1.00
151_D	423_G	1.113	1.00
151_D	154_N	1.112	1.00
225_L	301_T	1.109	1.00
220_E	224_A	1.109	1.00
531_E	562_Y	1.106	1.00
303_S	307_K	1.101	1.00
146_M	431_S	1.099	1.00
489_T	602_L	1.098	1.00
360_V	381_M	1.098	1.00
410_G	416_V	1.096	1.00
400_G	618_I	1.096	1.00
102_V	133_V	1.093	1.00
126_A	178_L	1.090	1.00
93_E	96_N	1.087	1.00
528_M	558_L	1.083	1.00
198_E	201_K	1.078	1.00
170_Q	174_A	1.078	1.00
395_G	409_E	1.078	1.00
499_L	508_R	1.077	1.00
618_I	622_K	1.076	1.00
630_I	634_K	1.073	1.00
430_S	461_S	1.068	1.00
237_S	244_N	1.055	1.00
623_A	635_K	1.054	1.00
192_Q	196_E	1.054	1.00
209_E	212_K	1.051	1.00
389_K	393_L	1.050	1.00
326_L	336_Y	1.050	1.00
131_D	473_Y	1.046	1.00
163_K	167_L	1.044	1.00
109_L	126_A	1.042	1.00
342_T	647_E	1.038	1.00
604_S	648_A	1.038	1.00
337_D	538_T	1.036	1.00
284_F	288_Y	1.035	1.00
232_V	581_P	1.034	1.00
305_T	309_D	1.032	1.00
147_R	150_Q	1.029	1.00
397_A	408_K	1.027	1.00
226_L	305_T	1.026	1.00
630_I	639_D	1.026	1.00
306_V	536_I	1.025	1.00
265_H	269_I	1.025	1.00
492_A	603_S	1.022	1.00
294_Y	297_T	1.020	1.00
81_D	419_Y	1.019	0.99
401_E	611_K	1.019	0.99
184_S	187_E	1.018	0.99
526_Q	529_F	1.017	0.99
128_T	189_K	1.017	0.99
502_L	507_Q	1.017	0.99
601_A	638_V	1.016	0.99
166_N	170_Q	1.015	0.99
479_S	629_P	1.012	0.99
534_H	538_T	1.011	0.99
217_V	221_K	1.008	0.99
279_V	282_N	1.007	0.99
378_D	382_K	1.005	0.99
558_L	562_Y	1.005	0.99
416_V	458_F	1.001	0.99
156_F	159_G	0.996	0.99
335_V	338_N	0.995	0.99
214_R	218_L	0.993	0.99
239_T	242_V	0.992	0.99
271_F	283_A	0.991	0.99
535_L	558_L	0.989	0.99
142_T	431_S	0.985	0.99
630_I	640_M	0.983	0.99
261_K	267_N	0.983	0.99
88_I	436_T	0.982	0.99
263_I	271_F	0.982	0.99
289_K	293_Q	0.981	0.99
169_T	173_S	0.974	0.99
358_K	365_E	0.974	0.99
355_A	566_G	0.972	0.99
350_L	524_F	0.971	0.99
382_K	446_N	0.971	0.99
239_T	243_L	0.969	0.99
623_A	626_S	0.966	0.99
352_R	355_A	0.966	0.99
402_E	618_I	0.965	0.99
242_V	260_E	0.963	0.99
361_L	364_D	0.963	0.99
271_F	274_S	0.960	0.99
617_Y	621_L	0.958	0.99
92_D	160_L	0.958	0.99
552_T	556_Y	0.958	0.99
354_I	371_L	0.956	0.99
183_L	186_E	0.953	0.99
609_E	616_R	0.951	0.99
153_G	423_G	0.950	0.99
189_K	192_Q	0.948	0.99
229_A	311_F	0.947	0.99
110_S	113_K	0.944	0.99
177_Y	181_E	0.944	0.99
228_E	231_E	0.943	0.99
632_V	635_K	0.943	0.99
146_M	439_Y	0.943	0.99
497_Y	501_N	0.942	0.99
340_V	531_E	0.941	0.99
99_F	103_K	0.937	0.99
237_S	241_S	0.931	0.99
265_H	287_V	0.931	0.99
392_M	446_N	0.930	0.99
167_L	178_L	0.929	0.99
190_L	193_F	0.924	0.99
431_S	439_Y	0.924	0.99
387_E	390_D	0.922	0.99
472_P	475_Y	0.921	0.99
95_W	99_F	0.920	0.99
355_A	359_K	0.920	0.99
479_S	482_V	0.918	0.99
96_N	99_F	0.916	0.99
333_E	337_D	0.916	0.99
489_T	617_Y	0.914	0.99
536_I	551_L	0.914	0.99
128_T	132_K	0.911	0.99
128_T	131_D	0.911	0.99
277_R	370_D	0.910	0.99
95_W	164_A	0.905	0.99
395_G	455_V	0.905	0.99
146_M	433_A	0.902	0.99
103_K	167_L	0.902	0.99
302_L	306_V	0.899	0.99
536_I	577_W	0.899	0.99
492_A	599_A	0.898	0.99
643_P	647_E	0.898	0.99
98_E	102_V	0.898	0.99
238_N	242_V	0.896	0.99
164_A	167_L	0.893	0.99
584_Y	588_Y	0.887	0.99
107_P	170_Q	0.887	0.99
619_D	622_K	0.887	0.99
246_A	249_T	0.887	0.99
453_T	582_H	0.886	0.99
311_F	314_R	0.884	0.99
480_I	483_A	0.877	0.98
121_D	125_E	0.870	0.98
161_N	165_G	0.868	0.98
146_M	429_Y	0.867	0.98
363_L	366_V	0.867	0.98
468_R	622_K	0.866	0.98
605_Q	608_K	0.865	0.98
87_D	439_Y	0.865	0.98
394_K	497_Y	0.864	0.98
309_D	537_H	0.864	0.98
124_Y	197_K	0.861	0.98
496_E	500_N	0.858	0.98
456_H	484_E	0.856	0.98
124_Y	199_E	0.854	0.98
578_S	584_Y	0.851	0.98
237_S	240_F	0.842	0.98
457_E	460_H	0.841	0.98
141_Y	145_H	0.840	0.98
410_G	458_F	0.839	0.98
467_T	625_S	0.839	0.98
205_H	628_Y	0.839	0.98
215_P	219_S	0.839	0.98
166_N	178_L	0.838	0.98
361_L	374_P	0.838	0.98
191_Q	194_I	0.837	0.98
95_W	141_Y	0.833	0.98
145_H	149_D	0.833	0.98
287_V	290_T	0.832	0.98
311_F	315_V	0.830	0.98
489_T	606_I	0.825	0.98
238_N	241_S	0.825	0.98
552_T	574_G	0.824	0.98
615_D	619_D	0.823	0.98
121_D	197_K	0.822	0.98
407_L	458_F	0.821	0.98
308_K	312_Y	0.821	0.98
418_V	442_M	0.819	0.98
264_T	267_N	0.819	0.98
277_R	281_K	0.819	0.98
399_L	406_I	0.819	0.98
511_I	514_H	0.817	0.98
615_D	618_I	0.816	0.98
560_K	569_I	0.815	0.98
250_F	290_T	0.813	0.98
285_D	289_K	0.810	0.97
345_K	348_P	0.810	0.97
428_A	440_I	0.809	0.97
163_K	166_N	0.809	0.97
555_Y	559_N	0.806	0.97
89_F	136_R	0.805	0.97
383_V	444_W	0.802	0.97
388_A	415_W	0.802	0.97
101_A	104_E	0.801	0.97
522_T	526_Q	0.801	0.97
339_L	593_A	0.800	0.97
148_S	157_Y	0.798	0.97
209_E	213_E	0.798	0.97
539_K	554_V	0.797	0.97
307_K	311_F	0.796	0.97
299_A	578_S	0.795	0.97
112_Y	119_S	0.793	0.97
299_A	548_P	0.792	0.97
247_D	255_D	0.789	0.97
91_S	147_R	0.788	0.97
341_K	531_E	0.785	0.97
467_T	476_G	0.783	0.97
242_V	256_E	0.782	0.97
442_M	453_T	0.782	0.97
171_A	174_A	0.782	0.97
105_L	132_K	0.781	0.97
235_S	239_T	0.781	0.97
284_F	368_I	0.779	0.97
385_Y	418_V	0.777	0.97
391_Y	451_L	0.775	0.97
256_E	279_V	0.774	0.97
432_G	435_G	0.774	0.97
281_K	367_H	0.774	0.97
388_A	444_W	0.773	0.97
501_N	504_D	0.773	0.97
205_H	209_E	0.772	0.97
381_M	384_T	0.770	0.97
619_D	623_A	0.769	0.97
405_S	408_K	0.765	0.96
103_K	106_I	0.765	0.96
150_Q	441_L	0.765	0.96
446_N	450_N	0.762	0.96
606_I	610_G	0.762	0.96
145_H	431_S	0.760	0.96
99_F	163_K	0.758	0.96
175_T	181_E	0.758	0.96
310_N	540_A	0.757	0.96
155_S	158_Q	0.757	0.96
547_T	550_L	0.757	0.96
290_T	293_Q	0.755	0.96
154_N	157_Y	0.752	0.96
137_L	168_Y	0.752	0.96
267_N	420_E	0.751	0.96
171_A	175_T	0.751	0.96
344_N	531_E	0.750	0.96
438_P	464_S	0.750	0.96
330_S	628_Y	0.748	0.96
526_Q	593_A	0.748	0.96
253_I	261_K	0.744	0.96
388_A	395_G	0.743	0.96
381_M	507_Q	0.743	0.96
571_K	574_G	0.742	0.96
449_N	452_F	0.742	0.96
598_A	640_M	0.741	0.96
367_H	569_I	0.741	0.96
105_L	134_M	0.738	0.96
107_P	174_A	0.737	0.96
280_R	370_D	0.737	0.96
271_F	279_V	0.737	0.96
489_T	603_S	0.736	0.96
129_Y	132_K	0.735	0.96
240_F	260_E	0.733	0.95
153_G	422_K	0.733	0.95
102_V	105_L	0.732	0.95
239_T	300_T	0.731	0.95
580_I	583_F	0.729	0.95
188_D	470_H	0.728	0.95
375_L	518_G	0.728	0.95
400_G	407_L	0.727	0.95
276_N	279_V	0.726	0.95
128_T	199_E	0.725	0.95
261_K	279_V	0.725	0.95
125_E	128_T	0.725	0.95
338_N	341_K	0.725	0.95
334_E	337_D	0.723	0.95
221_K	225_L	0.721	0.95
523_V	593_A	0.721	0.95
456_H	592_Y	0.721	0.95
336_Y	534_H	0.716	0.95
322_R	333_E	0.715	0.95
567_M	570_D	0.714	0.95
367_H	570_D	0.713	0.95
438_P	465_Y	0.713	0.95
555_Y	576_E	0.713	0.95
576_E	579_R	0.711	0.95
553_N	556_Y	0.710	0.95
125_E	129_Y	0.709	0.95
323_E	327_S	0.709	0.95
322_R	337_D	0.708	0.95
205_H	330_S	0.707	0.94
427_G	588_Y	0.707	0.94
457_E	491_E	0.705	0.94
502_L	505_E	0.704	0.94
92_D	159_G	0.703	0.94
286_A	290_T	0.702	0.94
213_E	216_H	0.700	0.94
376_V	379_A	0.699	0.94
166_N	173_S	0.698	0.94
433_A	439_Y	0.696	0.94
410_G	461_S	0.696	0.94
275_E	380_G	0.695	0.94
244_N	298_M	0.695	0.94
196_E	473_Y	0.695	0.94
322_R	534_H	0.693	0.94
303_S	551_L	0.692	0.94
404_A	408_K	0.691	0.94
527_T	593_A	0.690	0.94
478_Y	483_A	0.689	0.94
448_V	452_F	0.689	0.94
367_H	568_V	0.689	0.94
531_E	535_L	0.689	0.94
202_L	324_A	0.687	0.94
113_K	119_S	0.687	0.94
92_D	156_F	0.687	0.94
199_E	473_Y	0.687	0.94
269_I	372_Y	0.686	0.94
149_D	441_L	0.686	0.94
182_I	194_I	0.684	0.93
212_K	327_S	0.684	0.93
219_S	312_Y	0.683	0.93
238_N	296_N	0.683	0.93
96_N	167_L	0.682	0.93
482_V	632_V	0.682	0.93
483_A	486_A	0.681	0.93
336_Y	340_V	0.678	0.93
289_K	292_G	0.672	0.93
528_M	559_N	0.671	0.93
247_D	259_N	0.670	0.93
402_E	622_K	0.670	0.93
191_Q	204_S	0.670	0.93
305_T	586_N	0.669	0.93
366_V	371_L	0.669	0.93
393_L	404_A	0.667	0.93
410_G	415_W	0.667	0.93
361_L	366_V	0.667	0.93
428_A	453_T	0.666	0.93
189_K	193_F	0.665	0.93
333_E	538_T	0.665	0.93
162_D	171_A	0.663	0.92
457_E	484_E	0.661	0.92
354_I	366_V	0.659	0.92
292_G	575_L	0.659	0.92
373_T	377_K	0.659	0.92
82_T	421_N	0.659	0.92
240_F	243_L	0.657	0.92
493_L	606_I	0.657	0.92
610_G	613_A	0.656	0.92
508_R	512_L	0.655	0.92
357_R	366_V	0.655	0.92
358_K	363_L	0.655	0.92
452_F	494_L	0.652	0.92
236_S	240_F	0.648	0.92
331_I	336_Y	0.647	0.91
249_T	422_K	0.647	0.91
485_V	633_L	0.647	0.91
165_G	168_Y	0.647	0.91
257_D	282_N	0.644	0.91
167_L	170_Q	0.643	0.91
209_E	330_S	0.642	0.91
182_I	187_E	0.642	0.91
210_I	213_E	0.642	0.91
418_V	454_L	0.640	0.91
166_N	169_T	0.640	0.91
474_P	625_S	0.640	0.91
406_I	462_V	0.639	0.91
88_I	155_S	0.637	0.91
402_E	406_I	0.636	0.91
406_I	465_Y	0.636	0.91
229_A	312_Y	0.636	0.91
498_L	501_N	0.636	0.91
185_I	190_L	0.635	0.91
205_H	212_K	0.635	0.91
270_N	273_E	0.634	0.91
519_F	522_T	0.633	0.91
102_V	106_I	0.633	0.91
194_I	198_E	0.633	0.91
228_E	315_V	0.629	0.90
634_K	641_T	0.629	0.90
105_L	133_V	0.628	0.90
389_K	408_K	0.628	0.90
366_V	374_P	0.628	0.90
460_H	491_E	0.627	0.90
381_M	387_E	0.626	0.90
178_L	201_K	0.625	0.90
378_D	517_E	0.624	0.90
171_A	178_L	0.623	0.90
243_L	298_M	0.622	0.90
168_Y	172_A	0.622	0.90
321_A	325_A	0.621	0.90
342_T	642_S	0.621	0.90
196_E	199_E	0.621	0.90
397_A	406_I	0.621	0.90
615_D	622_K	0.620	0.90
119_S	193_F	0.620	0.90
140_L	164_A	0.618	0.90
149_D	425_R	0.618	0.90
421_N	424_K	0.617	0.89
95_W	98_E	0.617	0.89
105_L	129_Y	0.615	0.89
556_Y	572_E	0.615	0.89
256_E	261_K	0.615	0.89
323_E	334_E	0.615	0.89
102_V	167_L	0.614	0.89
495_G	511_I	0.613	0.89
188_D	191_Q	0.613	0.89
432_G	464_S	0.612	0.89
126_A	129_Y	0.610	0.89
102_V	109_L	0.610	0.89
272_L	287_V	0.610	0.89
596_Y	599_A	0.609	0.89
581_P	585_Y	0.607	0.89
456_H	460_H	0.606	0.89
241_S	282_N	0.606	0.89
147_R	151_D	0.605	0.89
495_G	515_M	0.605	0.89
452_F	495_G	0.604	0.88
306_V	546_L	0.602	0.88
479_S	628_Y	0.601	0.88
122_H	129_Y	0.601	0.88
340_V	527_T	0.601	0.88
262_Q	422_K	0.598	0.88
103_K	174_A	0.598	0.88
92_D	157_Y	0.597	0.88
175_T	212_K	0.596	0.88
277_R	361_L	0.596	0.88
390_D	393_L	0.596	0.88
134_M	171_A	0.595	0.88
309_D	586_N	0.595	0.88
235_S	297_T	0.595	0.88
217_V	220_E	0.595	0.88
552_T	575_L	0.594	0.88
605_Q	613_A	0.592	0.87
103_K	163_K	0.591	0.87
312_Y	324_A	0.591	0.87
484_E	491_E	0.591	0.87
188_D	474_P	0.590	0.87
463_H	478_Y	0.590	0.87
161_N	174_A	0.590	0.87
232_V	236_S	0.590	0.87
416_V	442_M	0.589	0.87
354_I	520_R	0.589	0.87
487_S	582_H	0.589	0.87
102_V	140_L	0.588	0.87
150_Q	421_N	0.588	0.87
218_L	312_Y	0.587	0.87
420_E	443_N	0.585	0.87
156_F	160_L	0.585	0.87
342_T	345_K	0.585	0.87
532_F	555_Y	0.585	0.87
160_L	163_K	0.585	0.87
94_A	98_E	0.585	0.87
416_V	461_S	0.585	0.87
231_E	296_N	0.584	0.87
517_E	520_R	0.584	0.87
619_D	627_Q	0.583	0.87
177_Y	180_P	0.583	0.87
371_L	521_G	0.581	0.86
385_Y	511_I	0.580	0.86
511_I	515_M	0.579	0.86
444_W	450_N	0.579	0.86
132_K	135_E	0.578	0.86
152_T	425_R	0.577	0.86
492_A	600_Q	0.577	0.86
192_Q	471_Q	0.577	0.86
392_M	458_F	0.575	0.86
277_R	364_D	0.575	0.86
456_H	491_E	0.574	0.86
448_V	511_I	0.574	0.86
174_A	177_Y	0.574	0.86
186_E	470_H	0.574	0.86
614_V	618_I	0.572	0.86
616_R	635_K	0.572	0.86
582_H	589_V	0.571	0.86
300_T	303_S	0.571	0.86
319_K	333_E	0.570	0.85
253_I	271_F	0.569	0.85
425_R	429_Y	0.569	0.85
99_F	140_L	0.568	0.85
620_F	632_V	0.568	0.85
135_E	139_R	0.567	0.85
528_M	576_E	0.567	0.85
202_L	475_Y	0.566	0.85
427_G	582_H	0.566	0.85
174_A	178_L	0.566	0.85
176_A	179_V	0.566	0.85
290_T	294_Y	0.565	0.85
182_I	190_L	0.565	0.85
112_Y	125_E	0.564	0.85
401_E	404_A	0.563	0.85
363_L	367_H	0.563	0.85
484_E	592_Y	0.562	0.85
198_E	328_N	0.562	0.85
348_P	352_R	0.560	0.84
266_G	420_E	0.560	0.84
427_G	453_T	0.560	0.84
430_S	438_P	0.560	0.84
138_G	432_G	0.560	0.84
342_T	643_P	0.559	0.84
348_P	351_H	0.559	0.84
439_Y	444_W	0.559	0.84
284_F	369_Y	0.558	0.84
157_Y	160_L	0.558	0.84
92_D	95_W	0.557	0.84
229_A	232_V	0.555	0.84
162_D	166_N	0.555	0.84
580_I	589_V	0.554	0.84
387_E	391_Y	0.553	0.84
284_F	367_H	0.553	0.84
492_A	496_E	0.552	0.84
420_E	445_H	0.552	0.84
141_Y	164_A	0.551	0.83
142_T	477_N	0.551	0.83
378_D	383_V	0.551	0.83
152_T	157_Y	0.549	0.83
499_L	502_L	0.549	0.83
444_W	451_L	0.549	0.83
83_W	86_E	0.547	0.83
509_L	512_L	0.547	0.83
178_L	182_I	0.546	0.83
218_L	226_L	0.545	0.83
109_L	133_V	0.545	0.83
235_S	291_Y	0.545	0.83
303_S	540_A	0.545	0.83
236_S	244_N	0.544	0.83
194_I	204_S	0.544	0.83
353_Y	357_R	0.542	0.82
485_V	598_A	0.542	0.82
527_T	531_E	0.541	0.82
223_E	316_K	0.541	0.82
303_S	548_P	0.540	0.82
582_H	592_Y	0.540	0.82
235_S	304_G	0.539	0.82
89_F	101_A	0.539	0.82
139_R	436_T	0.539	0.82
386_E	389_K	0.539	0.82
230_S	581_P	0.538	0.82
554_V	558_L	0.538	0.82
295_K	575_L	0.538	0.82
489_T	599_A	0.537	0.82
149_D	431_S	0.536	0.82
175_T	178_L	0.535	0.82
633_L	640_M	0.534	0.82
417_D	421_N	0.534	0.82
292_G	299_A	0.533	0.81
251_P	286_A	0.533	0.81
256_E	282_N	0.532	0.81
396_L	490_N	0.532	0.81
452_F	511_I	0.531	0.81
529_F	580_I	0.531	0.81
162_D	173_S	0.531	0.81
347_L	524_F	0.531	0.81
505_E	508_R	0.530	0.81
167_L	173_S	0.530	0.81
523_V	596_Y	0.530	0.81
305_T	584_Y	0.529	0.81
428_A	483_A	0.529	0.81
460_H	484_E	0.529	0.81
609_E	614_V	0.529	0.81
354_I	521_G	0.528	0.81
158_Q	162_D	0.528	0.81
111_K	180_P	0.527	0.81
106_I	110_S	0.527	0.81
337_D	531_E	0.527	0.81
170_Q	220_E	0.526	0.81
120_A	124_Y	0.526	0.81
332_P	641_T	0.525	0.80
559_N	573_I	0.524	0.80
188_D	192_Q	0.524	0.80
169_T	230_S	0.524	0.80
306_V	537_H	0.524	0.80
298_M	578_S	0.523	0.80
88_I	153_G	0.523	0.80
250_F	286_A	0.521	0.80
559_N	576_E	0.521	0.80
331_I	591_Q	0.521	0.80
451_L	494_L	0.521	0.80
619_D	632_V	0.521	0.80
409_E	437_N	0.520	0.80
120_A	197_K	0.520	0.80
356_L	359_K	0.520	0.80
167_L	181_E	0.520	0.80
295_K	548_P	0.520	0.80
466_Y	622_K	0.519	0.80
471_Q	475_Y	0.519	0.80
331_I	590_Y	0.518	0.80
462_V	618_I	0.517	0.79
482_V	620_F	0.516	0.79
389_K	418_V	0.516	0.79
512_L	516_L	0.516	0.79
256_E	260_E	0.515	0.79
456_H	487_S	0.514	0.79
598_A	633_L	0.514	0.79
195_L	198_E	0.514	0.79
176_A	180_P	0.513	0.79
170_Q	173_S	0.513	0.79
503_E	507_Q	0.512	0.79
334_E	641_T	0.511	0.79
102_V	137_L	0.511	0.79
448_V	498_L	0.511	0.79
138_G	142_T	0.510	0.79
127_L	181_E	0.510	0.79
555_Y	558_L	0.510	0.79
277_R	365_E	0.508	0.78
525_R	576_E	0.508	0.78
101_A	132_K	0.508	0.78
529_F	576_E	0.507	0.78
513_N	517_E	0.507	0.78
294_Y	298_M	0.507	0.78
464_S	467_T	0.507	0.78
279_V	283_A	0.506	0.78
112_Y	126_A	0.506	0.78
309_D	321_A	0.505	0.78
471_Q	474_P	0.505	0.78
638_V	648_A	0.505	0.78
284_F	572_E	0.503	0.78
405_S	409_E	0.503	0.78
319_K	334_E	0.503	0.78
551_L	555_Y	0.502	0.77
480_I	591_Q	0.502	0.77
514_H	518_G	0.502	0.77
179_V	210_I	0.501	0.77
80_E	409_E	0.501	0.77
152_T	423_G	0.501	0.77
495_G	518_G	0.500	0.77
136_R	140_L	0.500	0.77
489_T	492_A	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ce2A	1	0.8791	100	0.302	Contact Map
4ka7A	1	0.8507	100	0.324	Contact Map
2qr4A	2	0.7776	100	0.329	Contact Map
1y791	1	0.8537	100	0.33	Contact Map
2o3eA	1	0.8299	100	0.339	Contact Map
2o36A	1	0.8134	100	0.358	Contact Map
3sksA	1	0.794	100	0.418	Contact Map
3ahnA	1	0.8179	100	0.423	Contact Map
1r42A	1	0.7627	100	0.521	Contact Map
4ca6A	1	0.7716	100	0.531	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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