GREMLIN Database
PEPF - Oligoendopeptidase F homolog
UniProt: O31605 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 670 (553)
Sequences: 6285 (4310)
Seq/√Len: 183.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
281_K285_D7.0731.00
221_K304_G5.8421.00
319_K323_E5.3691.00
634_K639_D5.0431.00
214_R311_F4.7201.00
627_Q635_K3.8461.00
627_Q631_D3.7911.00
320_S323_E3.5761.00
251_P275_E3.5681.00
605_Q616_R3.4811.00
275_E373_T3.4431.00
278_E281_K3.3291.00
96_N163_K3.2851.00
208_E211_T3.1791.00
550_L553_N3.0801.00
89_F98_E3.0441.00
103_K170_Q3.0361.00
97_K101_A3.0211.00
553_N557_D3.0091.00
344_N561_K2.9091.00
616_R619_D2.8761.00
408_K465_Y2.7671.00
619_D635_K2.7571.00
310_N314_R2.7461.00
300_T304_G2.6601.00
323_E333_E2.6491.00
97_K100_Q2.6011.00
557_D561_K2.5351.00
182_I185_I2.4891.00
249_T276_N2.4491.00
219_S222_E2.4101.00
100_Q104_E2.3811.00
556_Y560_K2.3581.00
278_E282_N2.3341.00
611_K615_D2.3001.00
355_A358_K2.2661.00
96_N100_Q2.2661.00
393_L408_K2.2551.00
241_S244_N2.2161.00
318_Y327_S2.1781.00
539_K550_L2.1491.00
186_E189_K2.1481.00
627_Q632_V2.1331.00
101_A136_R2.0631.00
605_Q609_E2.0211.00
275_E377_K1.9981.00
98_E136_R1.9981.00
107_P111_K1.9911.00
252_S260_E1.9851.00
90_P94_A1.9771.00
124_Y128_T1.9681.00
440_I461_S1.9661.00
358_K361_L1.9601.00
535_L539_K1.9591.00
390_D394_K1.9121.00
218_L308_K1.9101.00
535_L557_D1.8961.00
623_A632_V1.8941.00
384_T387_E1.8641.00
334_E338_N1.8591.00
356_L382_K1.8591.00
281_K369_Y1.8431.00
149_D429_Y1.8431.00
341_K345_K1.8391.00
554_V557_D1.8391.00
509_L513_N1.8341.00
92_D96_N1.8191.00
384_T444_W1.8131.00
84_R387_E1.8081.00
190_L194_I1.8031.00
155_S159_G1.8001.00
337_D534_H1.7831.00
631_D635_K1.7761.00
346_H647_E1.7641.00
402_E405_S1.7571.00
609_E612_P1.7481.00
535_L554_V1.7441.00
216_H317_K1.7421.00
92_D163_K1.7211.00
103_K107_P1.7181.00
222_E305_T1.7031.00
100_Q103_K1.6941.00
225_L315_V1.6931.00
525_R529_F1.6761.00
302_L536_I1.6721.00
292_G295_K1.6711.00
623_A627_Q1.6631.00
295_K552_T1.6401.00
349_L352_R1.6341.00
604_S608_K1.6331.00
535_L538_T1.6181.00
105_L108_N1.6041.00
557_D560_K1.6021.00
430_S464_S1.6021.00
98_E140_L1.6011.00
240_F244_N1.5831.00
394_K501_N1.5751.00
239_T244_N1.5691.00
82_T85_L1.5621.00
274_S279_V1.5611.00
448_V495_G1.5471.00
84_R87_D1.5391.00
159_G163_K1.5361.00
388_A393_L1.5301.00
108_N129_Y1.5291.00
119_S122_H1.5221.00
552_T577_W1.5171.00
214_R217_V1.5141.00
496_E607_L1.5121.00
337_D341_K1.5101.00
631_D634_K1.5081.00
98_E101_A1.5081.00
277_R367_H1.5061.00
338_N342_T1.5001.00
105_L136_R1.4971.00
351_H355_A1.4911.00
175_T179_V1.4901.00
221_K224_A1.4891.00
201_K204_S1.4861.00
612_P615_D1.4831.00
347_L523_V1.4811.00
79_A82_T1.4761.00
392_M455_V1.4751.00
272_L283_A1.4711.00
277_R363_L1.4671.00
365_E568_V1.4611.00
320_S538_T1.4501.00
612_P616_R1.4461.00
332_P335_V1.4411.00
108_N111_K1.4301.00
628_Y631_D1.4291.00
609_E613_A1.4201.00
268_F283_A1.4161.00
101_A105_L1.4141.00
231_E298_M1.4131.00
604_S607_L1.4041.00
312_Y321_A1.3981.00
314_R541_Q1.3961.00
135_E435_G1.3911.00
277_R369_Y1.3851.00
310_N541_Q1.3731.00
94_A97_K1.3721.00
204_S208_E1.3711.00
255_D259_N1.3711.00
212_K330_S1.3711.00
249_T262_Q1.3661.00
342_T346_H1.3621.00
182_I186_E1.3531.00
191_Q195_L1.3441.00
104_E107_P1.3391.00
201_K206_A1.3391.00
325_A329_N1.3391.00
187_E191_Q1.3341.00
397_A404_A1.3341.00
107_P110_S1.3321.00
393_L415_W1.3321.00
236_S239_T1.3281.00
341_K561_K1.3251.00
87_D90_P1.3231.00
556_Y574_G1.3181.00
329_N591_Q1.3181.00
213_E217_V1.3171.00
485_V602_L1.3161.00
254_K260_E1.3161.00
642_S645_P1.3091.00
401_E405_S1.3011.00
218_L222_E1.2941.00
224_A228_E1.2861.00
445_H450_N1.2841.00
286_A289_K1.2741.00
91_S94_A1.2741.00
87_D437_N1.2731.00
122_H125_E1.2701.00
644_E648_A1.2541.00
326_L329_N1.2511.00
394_K397_A1.2461.00
400_G405_S1.2421.00
549_E553_N1.2361.00
222_E225_L1.2341.00
261_K283_A1.2261.00
282_N286_A1.2131.00
263_I286_A1.2111.00
504_D507_Q1.1991.00
320_S333_E1.1951.00
343_I527_T1.1911.00
358_K364_D1.1911.00
304_G307_K1.1901.00
148_S161_N1.1861.00
159_G162_D1.1861.00
447_N450_N1.1771.00
95_W140_L1.1771.00
345_K647_E1.1711.00
178_L181_E1.1681.00
93_E97_K1.1651.00
302_L551_L1.1651.00
189_K471_Q1.1551.00
211_T214_R1.1541.00
345_K643_P1.1511.00
104_E108_N1.1501.00
535_L561_K1.1501.00
249_T282_N1.1481.00
202_L327_S1.1451.00
406_I409_E1.1431.00
99_F167_L1.1411.00
268_F272_L1.1371.00
197_K201_K1.1341.00
102_V171_A1.1341.00
302_L577_W1.1231.00
285_D572_E1.1211.00
268_F287_V1.1181.00
529_F583_F1.1181.00
534_H587_Y1.1161.00
192_Q474_P1.1141.00
86_E90_P1.1141.00
151_D423_G1.1131.00
151_D154_N1.1121.00
225_L301_T1.1091.00
220_E224_A1.1091.00
531_E562_Y1.1061.00
303_S307_K1.1011.00
146_M431_S1.0991.00
489_T602_L1.0981.00
360_V381_M1.0981.00
410_G416_V1.0961.00
400_G618_I1.0961.00
102_V133_V1.0931.00
126_A178_L1.0901.00
93_E96_N1.0871.00
528_M558_L1.0831.00
198_E201_K1.0781.00
170_Q174_A1.0781.00
395_G409_E1.0781.00
499_L508_R1.0771.00
618_I622_K1.0761.00
630_I634_K1.0731.00
430_S461_S1.0681.00
237_S244_N1.0551.00
623_A635_K1.0541.00
192_Q196_E1.0541.00
209_E212_K1.0511.00
389_K393_L1.0501.00
326_L336_Y1.0501.00
131_D473_Y1.0461.00
163_K167_L1.0441.00
109_L126_A1.0421.00
342_T647_E1.0381.00
604_S648_A1.0381.00
337_D538_T1.0361.00
284_F288_Y1.0351.00
232_V581_P1.0341.00
305_T309_D1.0321.00
147_R150_Q1.0291.00
397_A408_K1.0271.00
226_L305_T1.0261.00
630_I639_D1.0261.00
306_V536_I1.0251.00
265_H269_I1.0251.00
492_A603_S1.0221.00
294_Y297_T1.0201.00
81_D419_Y1.0190.99
401_E611_K1.0190.99
184_S187_E1.0180.99
526_Q529_F1.0170.99
128_T189_K1.0170.99
502_L507_Q1.0170.99
601_A638_V1.0160.99
166_N170_Q1.0150.99
479_S629_P1.0120.99
534_H538_T1.0110.99
217_V221_K1.0080.99
279_V282_N1.0070.99
378_D382_K1.0050.99
558_L562_Y1.0050.99
416_V458_F1.0010.99
156_F159_G0.9960.99
335_V338_N0.9950.99
214_R218_L0.9930.99
239_T242_V0.9920.99
271_F283_A0.9910.99
535_L558_L0.9890.99
142_T431_S0.9850.99
630_I640_M0.9830.99
261_K267_N0.9830.99
88_I436_T0.9820.99
263_I271_F0.9820.99
289_K293_Q0.9810.99
169_T173_S0.9740.99
358_K365_E0.9740.99
355_A566_G0.9720.99
350_L524_F0.9710.99
382_K446_N0.9710.99
239_T243_L0.9690.99
623_A626_S0.9660.99
352_R355_A0.9660.99
402_E618_I0.9650.99
242_V260_E0.9630.99
361_L364_D0.9630.99
271_F274_S0.9600.99
617_Y621_L0.9580.99
92_D160_L0.9580.99
552_T556_Y0.9580.99
354_I371_L0.9560.99
183_L186_E0.9530.99
609_E616_R0.9510.99
153_G423_G0.9500.99
189_K192_Q0.9480.99
229_A311_F0.9470.99
110_S113_K0.9440.99
177_Y181_E0.9440.99
228_E231_E0.9430.99
632_V635_K0.9430.99
146_M439_Y0.9430.99
497_Y501_N0.9420.99
340_V531_E0.9410.99
99_F103_K0.9370.99
237_S241_S0.9310.99
265_H287_V0.9310.99
392_M446_N0.9300.99
167_L178_L0.9290.99
190_L193_F0.9240.99
431_S439_Y0.9240.99
387_E390_D0.9220.99
472_P475_Y0.9210.99
95_W99_F0.9200.99
355_A359_K0.9200.99
479_S482_V0.9180.99
96_N99_F0.9160.99
333_E337_D0.9160.99
489_T617_Y0.9140.99
536_I551_L0.9140.99
128_T132_K0.9110.99
128_T131_D0.9110.99
277_R370_D0.9100.99
95_W164_A0.9050.99
395_G455_V0.9050.99
146_M433_A0.9020.99
103_K167_L0.9020.99
302_L306_V0.8990.99
536_I577_W0.8990.99
492_A599_A0.8980.99
643_P647_E0.8980.99
98_E102_V0.8980.99
238_N242_V0.8960.99
164_A167_L0.8930.99
584_Y588_Y0.8870.99
107_P170_Q0.8870.99
619_D622_K0.8870.99
246_A249_T0.8870.99
453_T582_H0.8860.99
311_F314_R0.8840.99
480_I483_A0.8770.98
121_D125_E0.8700.98
161_N165_G0.8680.98
146_M429_Y0.8670.98
363_L366_V0.8670.98
468_R622_K0.8660.98
605_Q608_K0.8650.98
87_D439_Y0.8650.98
394_K497_Y0.8640.98
309_D537_H0.8640.98
124_Y197_K0.8610.98
496_E500_N0.8580.98
456_H484_E0.8560.98
124_Y199_E0.8540.98
578_S584_Y0.8510.98
237_S240_F0.8420.98
457_E460_H0.8410.98
141_Y145_H0.8400.98
410_G458_F0.8390.98
467_T625_S0.8390.98
205_H628_Y0.8390.98
215_P219_S0.8390.98
166_N178_L0.8380.98
361_L374_P0.8380.98
191_Q194_I0.8370.98
95_W141_Y0.8330.98
145_H149_D0.8330.98
287_V290_T0.8320.98
311_F315_V0.8300.98
489_T606_I0.8250.98
238_N241_S0.8250.98
552_T574_G0.8240.98
615_D619_D0.8230.98
121_D197_K0.8220.98
407_L458_F0.8210.98
308_K312_Y0.8210.98
418_V442_M0.8190.98
264_T267_N0.8190.98
277_R281_K0.8190.98
399_L406_I0.8190.98
511_I514_H0.8170.98
615_D618_I0.8160.98
560_K569_I0.8150.98
250_F290_T0.8130.98
285_D289_K0.8100.97
345_K348_P0.8100.97
428_A440_I0.8090.97
163_K166_N0.8090.97
555_Y559_N0.8060.97
89_F136_R0.8050.97
383_V444_W0.8020.97
388_A415_W0.8020.97
101_A104_E0.8010.97
522_T526_Q0.8010.97
339_L593_A0.8000.97
148_S157_Y0.7980.97
209_E213_E0.7980.97
539_K554_V0.7970.97
307_K311_F0.7960.97
299_A578_S0.7950.97
112_Y119_S0.7930.97
299_A548_P0.7920.97
247_D255_D0.7890.97
91_S147_R0.7880.97
341_K531_E0.7850.97
467_T476_G0.7830.97
242_V256_E0.7820.97
442_M453_T0.7820.97
171_A174_A0.7820.97
105_L132_K0.7810.97
235_S239_T0.7810.97
284_F368_I0.7790.97
385_Y418_V0.7770.97
391_Y451_L0.7750.97
256_E279_V0.7740.97
432_G435_G0.7740.97
281_K367_H0.7740.97
388_A444_W0.7730.97
501_N504_D0.7730.97
205_H209_E0.7720.97
381_M384_T0.7700.97
619_D623_A0.7690.97
405_S408_K0.7650.96
103_K106_I0.7650.96
150_Q441_L0.7650.96
446_N450_N0.7620.96
606_I610_G0.7620.96
145_H431_S0.7600.96
99_F163_K0.7580.96
175_T181_E0.7580.96
310_N540_A0.7570.96
155_S158_Q0.7570.96
547_T550_L0.7570.96
290_T293_Q0.7550.96
154_N157_Y0.7520.96
137_L168_Y0.7520.96
267_N420_E0.7510.96
171_A175_T0.7510.96
344_N531_E0.7500.96
438_P464_S0.7500.96
330_S628_Y0.7480.96
526_Q593_A0.7480.96
253_I261_K0.7440.96
388_A395_G0.7430.96
381_M507_Q0.7430.96
571_K574_G0.7420.96
449_N452_F0.7420.96
598_A640_M0.7410.96
367_H569_I0.7410.96
105_L134_M0.7380.96
107_P174_A0.7370.96
280_R370_D0.7370.96
271_F279_V0.7370.96
489_T603_S0.7360.96
129_Y132_K0.7350.96
240_F260_E0.7330.95
153_G422_K0.7330.95
102_V105_L0.7320.95
239_T300_T0.7310.95
580_I583_F0.7290.95
188_D470_H0.7280.95
375_L518_G0.7280.95
400_G407_L0.7270.95
276_N279_V0.7260.95
128_T199_E0.7250.95
261_K279_V0.7250.95
125_E128_T0.7250.95
338_N341_K0.7250.95
334_E337_D0.7230.95
221_K225_L0.7210.95
523_V593_A0.7210.95
456_H592_Y0.7210.95
336_Y534_H0.7160.95
322_R333_E0.7150.95
567_M570_D0.7140.95
367_H570_D0.7130.95
438_P465_Y0.7130.95
555_Y576_E0.7130.95
576_E579_R0.7110.95
553_N556_Y0.7100.95
125_E129_Y0.7090.95
323_E327_S0.7090.95
322_R337_D0.7080.95
205_H330_S0.7070.94
427_G588_Y0.7070.94
457_E491_E0.7050.94
502_L505_E0.7040.94
92_D159_G0.7030.94
286_A290_T0.7020.94
213_E216_H0.7000.94
376_V379_A0.6990.94
166_N173_S0.6980.94
433_A439_Y0.6960.94
410_G461_S0.6960.94
275_E380_G0.6950.94
244_N298_M0.6950.94
196_E473_Y0.6950.94
322_R534_H0.6930.94
303_S551_L0.6920.94
404_A408_K0.6910.94
527_T593_A0.6900.94
478_Y483_A0.6890.94
448_V452_F0.6890.94
367_H568_V0.6890.94
531_E535_L0.6890.94
202_L324_A0.6870.94
113_K119_S0.6870.94
92_D156_F0.6870.94
199_E473_Y0.6870.94
269_I372_Y0.6860.94
149_D441_L0.6860.94
182_I194_I0.6840.93
212_K327_S0.6840.93
219_S312_Y0.6830.93
238_N296_N0.6830.93
96_N167_L0.6820.93
482_V632_V0.6820.93
483_A486_A0.6810.93
336_Y340_V0.6780.93
289_K292_G0.6720.93
528_M559_N0.6710.93
247_D259_N0.6700.93
402_E622_K0.6700.93
191_Q204_S0.6700.93
305_T586_N0.6690.93
366_V371_L0.6690.93
393_L404_A0.6670.93
410_G415_W0.6670.93
361_L366_V0.6670.93
428_A453_T0.6660.93
189_K193_F0.6650.93
333_E538_T0.6650.93
162_D171_A0.6630.92
457_E484_E0.6610.92
354_I366_V0.6590.92
292_G575_L0.6590.92
373_T377_K0.6590.92
82_T421_N0.6590.92
240_F243_L0.6570.92
493_L606_I0.6570.92
610_G613_A0.6560.92
508_R512_L0.6550.92
357_R366_V0.6550.92
358_K363_L0.6550.92
452_F494_L0.6520.92
236_S240_F0.6480.92
331_I336_Y0.6470.91
249_T422_K0.6470.91
485_V633_L0.6470.91
165_G168_Y0.6470.91
257_D282_N0.6440.91
167_L170_Q0.6430.91
209_E330_S0.6420.91
182_I187_E0.6420.91
210_I213_E0.6420.91
418_V454_L0.6400.91
166_N169_T0.6400.91
474_P625_S0.6400.91
406_I462_V0.6390.91
88_I155_S0.6370.91
402_E406_I0.6360.91
406_I465_Y0.6360.91
229_A312_Y0.6360.91
498_L501_N0.6360.91
185_I190_L0.6350.91
205_H212_K0.6350.91
270_N273_E0.6340.91
519_F522_T0.6330.91
102_V106_I0.6330.91
194_I198_E0.6330.91
228_E315_V0.6290.90
634_K641_T0.6290.90
105_L133_V0.6280.90
389_K408_K0.6280.90
366_V374_P0.6280.90
460_H491_E0.6270.90
381_M387_E0.6260.90
178_L201_K0.6250.90
378_D517_E0.6240.90
171_A178_L0.6230.90
243_L298_M0.6220.90
168_Y172_A0.6220.90
321_A325_A0.6210.90
342_T642_S0.6210.90
196_E199_E0.6210.90
397_A406_I0.6210.90
615_D622_K0.6200.90
119_S193_F0.6200.90
140_L164_A0.6180.90
149_D425_R0.6180.90
421_N424_K0.6170.89
95_W98_E0.6170.89
105_L129_Y0.6150.89
556_Y572_E0.6150.89
256_E261_K0.6150.89
323_E334_E0.6150.89
102_V167_L0.6140.89
495_G511_I0.6130.89
188_D191_Q0.6130.89
432_G464_S0.6120.89
126_A129_Y0.6100.89
102_V109_L0.6100.89
272_L287_V0.6100.89
596_Y599_A0.6090.89
581_P585_Y0.6070.89
456_H460_H0.6060.89
241_S282_N0.6060.89
147_R151_D0.6050.89
495_G515_M0.6050.89
452_F495_G0.6040.88
306_V546_L0.6020.88
479_S628_Y0.6010.88
122_H129_Y0.6010.88
340_V527_T0.6010.88
262_Q422_K0.5980.88
103_K174_A0.5980.88
92_D157_Y0.5970.88
175_T212_K0.5960.88
277_R361_L0.5960.88
390_D393_L0.5960.88
134_M171_A0.5950.88
309_D586_N0.5950.88
235_S297_T0.5950.88
217_V220_E0.5950.88
552_T575_L0.5940.88
605_Q613_A0.5920.87
103_K163_K0.5910.87
312_Y324_A0.5910.87
484_E491_E0.5910.87
188_D474_P0.5900.87
463_H478_Y0.5900.87
161_N174_A0.5900.87
232_V236_S0.5900.87
416_V442_M0.5890.87
354_I520_R0.5890.87
487_S582_H0.5890.87
102_V140_L0.5880.87
150_Q421_N0.5880.87
218_L312_Y0.5870.87
420_E443_N0.5850.87
156_F160_L0.5850.87
342_T345_K0.5850.87
532_F555_Y0.5850.87
160_L163_K0.5850.87
94_A98_E0.5850.87
416_V461_S0.5850.87
231_E296_N0.5840.87
517_E520_R0.5840.87
619_D627_Q0.5830.87
177_Y180_P0.5830.87
371_L521_G0.5810.86
385_Y511_I0.5800.86
511_I515_M0.5790.86
444_W450_N0.5790.86
132_K135_E0.5780.86
152_T425_R0.5770.86
492_A600_Q0.5770.86
192_Q471_Q0.5770.86
392_M458_F0.5750.86
277_R364_D0.5750.86
456_H491_E0.5740.86
448_V511_I0.5740.86
174_A177_Y0.5740.86
186_E470_H0.5740.86
614_V618_I0.5720.86
616_R635_K0.5720.86
582_H589_V0.5710.86
300_T303_S0.5710.86
319_K333_E0.5700.85
253_I271_F0.5690.85
425_R429_Y0.5690.85
99_F140_L0.5680.85
620_F632_V0.5680.85
135_E139_R0.5670.85
528_M576_E0.5670.85
202_L475_Y0.5660.85
427_G582_H0.5660.85
174_A178_L0.5660.85
176_A179_V0.5660.85
290_T294_Y0.5650.85
182_I190_L0.5650.85
112_Y125_E0.5640.85
401_E404_A0.5630.85
363_L367_H0.5630.85
484_E592_Y0.5620.85
198_E328_N0.5620.85
348_P352_R0.5600.84
266_G420_E0.5600.84
427_G453_T0.5600.84
430_S438_P0.5600.84
138_G432_G0.5600.84
342_T643_P0.5590.84
348_P351_H0.5590.84
439_Y444_W0.5590.84
284_F369_Y0.5580.84
157_Y160_L0.5580.84
92_D95_W0.5570.84
229_A232_V0.5550.84
162_D166_N0.5550.84
580_I589_V0.5540.84
387_E391_Y0.5530.84
284_F367_H0.5530.84
492_A496_E0.5520.84
420_E445_H0.5520.84
141_Y164_A0.5510.83
142_T477_N0.5510.83
378_D383_V0.5510.83
152_T157_Y0.5490.83
499_L502_L0.5490.83
444_W451_L0.5490.83
83_W86_E0.5470.83
509_L512_L0.5470.83
178_L182_I0.5460.83
218_L226_L0.5450.83
109_L133_V0.5450.83
235_S291_Y0.5450.83
303_S540_A0.5450.83
236_S244_N0.5440.83
194_I204_S0.5440.83
353_Y357_R0.5420.82
485_V598_A0.5420.82
527_T531_E0.5410.82
223_E316_K0.5410.82
303_S548_P0.5400.82
582_H592_Y0.5400.82
235_S304_G0.5390.82
89_F101_A0.5390.82
139_R436_T0.5390.82
386_E389_K0.5390.82
230_S581_P0.5380.82
554_V558_L0.5380.82
295_K575_L0.5380.82
489_T599_A0.5370.82
149_D431_S0.5360.82
175_T178_L0.5350.82
633_L640_M0.5340.82
417_D421_N0.5340.82
292_G299_A0.5330.81
251_P286_A0.5330.81
256_E282_N0.5320.81
396_L490_N0.5320.81
452_F511_I0.5310.81
529_F580_I0.5310.81
162_D173_S0.5310.81
347_L524_F0.5310.81
505_E508_R0.5300.81
167_L173_S0.5300.81
523_V596_Y0.5300.81
305_T584_Y0.5290.81
428_A483_A0.5290.81
460_H484_E0.5290.81
609_E614_V0.5290.81
354_I521_G0.5280.81
158_Q162_D0.5280.81
111_K180_P0.5270.81
106_I110_S0.5270.81
337_D531_E0.5270.81
170_Q220_E0.5260.81
120_A124_Y0.5260.81
332_P641_T0.5250.80
559_N573_I0.5240.80
188_D192_Q0.5240.80
169_T230_S0.5240.80
306_V537_H0.5240.80
298_M578_S0.5230.80
88_I153_G0.5230.80
250_F286_A0.5210.80
559_N576_E0.5210.80
331_I591_Q0.5210.80
451_L494_L0.5210.80
619_D632_V0.5210.80
409_E437_N0.5200.80
120_A197_K0.5200.80
356_L359_K0.5200.80
167_L181_E0.5200.80
295_K548_P0.5200.80
466_Y622_K0.5190.80
471_Q475_Y0.5190.80
331_I590_Y0.5180.80
462_V618_I0.5170.79
482_V620_F0.5160.79
389_K418_V0.5160.79
512_L516_L0.5160.79
256_E260_E0.5150.79
456_H487_S0.5140.79
598_A633_L0.5140.79
195_L198_E0.5140.79
176_A180_P0.5130.79
170_Q173_S0.5130.79
503_E507_Q0.5120.79
334_E641_T0.5110.79
102_V137_L0.5110.79
448_V498_L0.5110.79
138_G142_T0.5100.79
127_L181_E0.5100.79
555_Y558_L0.5100.79
277_R365_E0.5080.78
525_R576_E0.5080.78
101_A132_K0.5080.78
529_F576_E0.5070.78
513_N517_E0.5070.78
294_Y298_M0.5070.78
464_S467_T0.5070.78
279_V283_A0.5060.78
112_Y126_A0.5060.78
309_D321_A0.5050.78
471_Q474_P0.5050.78
638_V648_A0.5050.78
284_F572_E0.5030.78
405_S409_E0.5030.78
319_K334_E0.5030.78
551_L555_Y0.5020.77
480_I591_Q0.5020.77
514_H518_G0.5020.77
179_V210_I0.5010.77
80_E409_E0.5010.77
152_T423_G0.5010.77
495_G518_G0.5000.77
136_R140_L0.5000.77
489_T492_A0.5000.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ce2A 1 0.8791 100 0.302 Contact Map
4ka7A 1 0.8507 100 0.324 Contact Map
2qr4A 2 0.7776 100 0.329 Contact Map
1y791 1 0.8537 100 0.33 Contact Map
2o3eA 1 0.8299 100 0.339 Contact Map
2o36A 1 0.8134 100 0.358 Contact Map
3sksA 1 0.794 100 0.418 Contact Map
3ahnA 1 0.8179 100 0.423 Contact Map
1r42A 1 0.7627 100 0.521 Contact Map
4ca6A 1 0.7716 100 0.531 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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