YFHQ - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFHQ - Probable A/G-specific adenine glycosylase YfhQ

UniProt:	O31584	Sequences: MNVLEDKLKQKDIQQFRDDLISWFEREQRVLPWREDQDPYKVWVSEVMLQQTRVETVIPYFLRFVEQFPTVEALADADEEKVLKAWEGLGYYSRVRNLQSAVKEVKQEYGGIVPPDEKDFGGLKGVGPYTKGAVLSIAYNKPIPAVDGNVMRVMSRILSIWDDIAKPKTRTIFEDAIRAFISKEKPSEFNQGLMELGALICTPKSPSCLLCPVQQHCSAFEEGTERELPVKSKKKKPGIKTMAAIVLTDEDGQVYIHKRPSKGLLANLWEFPNLETQKGIKTEREQLIAFLENEYGIQADISDLQGVVEHVFTHLVWNISVFFGKVKQVSDTSKLKKVTKEELEQFAFPVSHQKIWKMAGEAAAISAAP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	369 (335)
Sequences:	2953 (2214)
Seq/√Len:	121.0

ECOLI - MUTY
BACSU - YFHQ
HALSA - Q9HPQ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
70_T	73_A	4.704	1.00
116_D	119_D	4.082	1.00
25_E	185_K	3.909	1.00
67_Q	81_K	3.581	1.00
257_H	270_E	2.955	1.00
30_V	35_E	2.789	1.00
99_Q	103_K	2.762	1.00
159_S	218_S	2.706	1.00
185_K	188_E	2.635	1.00
67_Q	85_A	2.605	1.00
224_T	227_E	2.589	1.00
224_T	228_L	2.582	1.00
44_V	65_V	2.494	1.00
115_P	141_K	2.476	1.00
38_D	41_K	2.434	1.00
214_Q	220_F	2.336	1.00
80_E	347_A	2.284	1.00
84_K	87_E	2.265	1.00
248_T	323_F	2.259	1.00
62_L	66_E	2.253	1.00
311_V	316_V	2.203	1.00
68_F	85_A	2.191	1.00
100_S	124_K	2.189	1.00
117_E	143_I	2.153	1.00
207_S	210_L	2.119	1.00
120_F	135_L	2.032	1.00
104_E	124_K	2.018	1.00
117_E	121_G	1.999	1.00
19_D	216_H	1.979	1.00
157_I	216_H	1.938	1.00
104_E	108_E	1.933	1.00
28_Q	195_E	1.924	1.00
218_S	222_E	1.922	1.00
16_F	213_V	1.919	1.00
41_K	65_V	1.908	1.00
72_E	106_K	1.905	1.00
255_Y	335_L	1.902	1.00
167_P	171_T	1.899	1.00
49_L	54_V	1.882	1.00
38_D	42_V	1.881	1.00
136_S	190_N	1.868	1.00
239_I	318_N	1.859	1.00
159_S	222_E	1.839	1.00
238_G	315_L	1.830	1.00
248_T	325_K	1.812	1.00
21_I	188_E	1.767	1.00
109_Y	122_G	1.764	1.00
237_P	316_V	1.760	1.00
159_S	228_L	1.756	1.00
72_E	76_D	1.748	1.00
159_S	224_T	1.730	1.00
132_G	144_P	1.724	1.00
44_V	98_L	1.719	1.00
162_D	172_I	1.719	1.00
25_E	188_E	1.718	1.00
36_D	42_V	1.714	1.00
256_I	346_F	1.701	1.00
158_L	176_A	1.661	1.00
157_I	213_V	1.656	1.00
79_E	103_K	1.645	1.00
339_T	342_E	1.644	1.00
112_I	115_P	1.632	1.00
79_E	83_L	1.597	1.00
160_I	176_A	1.592	1.00
162_D	169_T	1.590	1.00
121_G	128_P	1.584	1.00
240_K	315_L	1.573	1.00
93_S	97_N	1.572	1.00
59_P	62_L	1.570	1.00
128_P	174_E	1.569	1.00
225_E	228_L	1.556	1.00
61_F	65_V	1.548	1.00
135_L	141_K	1.537	1.00
135_L	143_I	1.533	1.00
342_E	345_Q	1.522	1.00
79_E	99_Q	1.520	1.00
101_A	123_L	1.510	1.00
350_V	353_Q	1.509	1.00
78_D	81_K	1.507	1.00
144_P	178_R	1.504	1.00
220_F	225_E	1.503	1.00
36_D	41_K	1.499	1.00
24_F	191_Q	1.498	1.00
202_T	207_S	1.481	1.00
109_Y	119_D	1.478	1.00
349_P	352_H	1.472	1.00
119_D	122_G	1.462	1.00
21_I	25_E	1.457	1.00
104_E	109_Y	1.456	1.00
20_L	213_V	1.428	1.00
256_I	348_F	1.424	1.00
161_W	224_T	1.419	1.00
113_V	120_F	1.418	1.00
165_A	232_S	1.390	1.00
239_I	316_V	1.386	1.00
20_L	192_G	1.379	1.00
17_R	182_S	1.374	1.00
195_E	199_L	1.367	1.00
135_L	139_Y	1.362	1.00
117_E	141_K	1.359	1.00
241_T	318_N	1.356	1.00
97_N	100_S	1.356	1.00
309_E	318_N	1.352	1.00
338_V	346_F	1.340	1.00
244_A	319_I	1.335	1.00
309_E	316_V	1.326	1.00
100_S	103_K	1.313	1.00
154_M	193_L	1.305	1.00
74_L	82_V	1.303	1.00
82_V	99_Q	1.299	1.00
115_P	139_Y	1.295	1.00
260_P	263_G	1.295	1.00
95_V	98_L	1.277	1.00
144_P	181_I	1.268	1.00
101_A	104_E	1.259	0.99
71_V	113_V	1.259	0.99
307_V	320_S	1.258	0.99
161_W	228_L	1.258	0.99
161_W	230_V	1.252	0.99
321_V	355_I	1.243	0.99
181_I	193_L	1.242	0.99
253_Q	339_T	1.241	0.99
189_F	193_L	1.236	0.99
155_S	173_F	1.233	0.99
158_L	180_F	1.232	0.99
219_A	225_E	1.218	0.99
105_V	113_V	1.211	0.99
41_K	61_F	1.210	0.99
176_A	179_A	1.206	0.99
20_L	193_L	1.206	0.99
146_V	173_F	1.203	0.99
319_I	351_S	1.202	0.99
53_R	56_T	1.202	0.99
243_A	322_F	1.201	0.99
48_M	57_V	1.190	0.99
55_E	58_I	1.188	0.99
101_A	126_V	1.183	0.99
103_K	107_Q	1.165	0.99
208_C	217_C	1.161	0.99
218_S	221_E	1.152	0.99
303_D	323_F	1.152	0.99
126_V	134_V	1.150	0.99
21_I	185_K	1.146	0.99
106_K	109_Y	1.144	0.99
260_P	266_A	1.143	0.99
140_N	187_S	1.143	0.99
117_E	131_K	1.138	0.99
246_V	271_F	1.137	0.99
63_R	85_A	1.137	0.99
58_I	62_L	1.130	0.99
143_I	178_R	1.130	0.99
270_E	273_N	1.125	0.99
258_K	267_N	1.124	0.99
116_D	141_K	1.119	0.99
171_T	175_D	1.117	0.99
43_W	47_V	1.104	0.99
42_V	138_A	1.100	0.99
76_D	106_K	1.097	0.99
188_E	192_G	1.090	0.99
142_P	183_K	1.079	0.98
145_A	174_E	1.068	0.98
246_V	355_I	1.058	0.98
120_F	143_I	1.057	0.98
80_E	258_K	1.053	0.98
120_F	134_V	1.052	0.98
306_G	358_M	1.051	0.98
137_I	187_S	1.048	0.98
208_C	211_C	1.038	0.98
177_I	189_F	1.033	0.98
167_P	170_R	1.031	0.98
196_L	212_P	1.030	0.98
257_H	334_K	1.029	0.98
211_C	217_C	1.023	0.98
269_W	337_K	1.015	0.98
20_L	196_L	1.014	0.98
242_M	273_N	1.010	0.98
172_I	176_A	1.007	0.98
21_I	192_G	1.005	0.98
182_S	186_P	1.002	0.97
37_Q	140_N	1.000	0.97
132_G	145_A	0.993	0.97
201_C	211_C	0.993	0.97
24_F	34_R	0.989	0.97
117_E	135_L	0.986	0.97
154_M	177_I	0.986	0.97
77_A	82_V	0.985	0.97
154_M	180_F	0.980	0.97
79_E	261_S	0.979	0.97
336_K	346_F	0.977	0.97
264_L	315_L	0.974	0.97
151_M	164_I	0.963	0.97
201_C	208_C	0.958	0.97
17_R	183_K	0.955	0.97
68_F	77_A	0.951	0.97
252_G	340_K	0.948	0.96
338_V	343_L	0.941	0.96
256_I	338_V	0.938	0.96
105_V	120_F	0.938	0.96
241_T	320_S	0.930	0.96
120_F	126_V	0.921	0.96
186_P	190_N	0.919	0.96
150_V	195_E	0.918	0.96
165_A	233_K	0.918	0.96
18_D	22_S	0.914	0.96
201_C	217_C	0.913	0.96
24_F	28_Q	0.904	0.95
151_M	170_R	0.903	0.95
248_T	252_G	0.901	0.95
258_K	334_K	0.897	0.95
245_I	274_L	0.895	0.95
182_S	189_F	0.894	0.95
142_P	178_R	0.893	0.95
166_K	169_T	0.892	0.95
187_S	192_G	0.889	0.95
265_L	312_F	0.889	0.95
263_G	266_A	0.886	0.95
39_P	139_Y	0.882	0.95
247_L	255_Y	0.881	0.95
68_F	81_K	0.872	0.94
33_W	57_V	0.870	0.94
235_K	313_T	0.868	0.94
118_K	122_G	0.852	0.94
108_E	122_G	0.852	0.94
195_E	198_A	0.851	0.94
242_M	319_I	0.848	0.94
264_L	312_F	0.847	0.93
48_M	56_T	0.846	0.93
129_Y	146_V	0.842	0.93
31_L	54_V	0.841	0.93
122_G	135_L	0.838	0.93
269_W	336_K	0.836	0.93
82_V	95_V	0.831	0.93
307_V	318_N	0.831	0.93
24_F	192_G	0.829	0.93
129_Y	145_A	0.819	0.92
54_V	57_V	0.816	0.92
196_L	200_I	0.812	0.92
15_Q	19_D	0.811	0.92
73_A	76_D	0.808	0.92
242_M	317_W	0.807	0.92
79_E	93_S	0.804	0.92
248_T	254_V	0.804	0.92
164_I	230_V	0.802	0.91
19_D	215_Q	0.801	0.91
47_V	134_V	0.799	0.91
37_Q	42_V	0.798	0.91
174_E	178_R	0.797	0.91
332_T	335_L	0.790	0.91
350_V	354_K	0.789	0.91
259_R	270_E	0.788	0.91
29_R	198_A	0.786	0.91
43_W	71_V	0.785	0.91
271_F	356_W	0.784	0.91
21_I	24_F	0.783	0.90
37_Q	137_I	0.781	0.90
306_G	321_V	0.781	0.90
84_K	346_F	0.779	0.90
170_R	174_E	0.779	0.90
172_I	175_D	0.778	0.90
145_A	150_V	0.776	0.90
132_G	174_E	0.773	0.90
44_V	95_V	0.773	0.90
253_Q	342_E	0.773	0.90
312_F	315_L	0.772	0.90
121_G	131_K	0.771	0.90
146_V	174_E	0.769	0.90
34_R	129_Y	0.768	0.90
33_W	49_L	0.768	0.90
21_I	137_I	0.765	0.89
71_V	105_V	0.765	0.89
153_V	196_L	0.760	0.89
78_D	99_Q	0.760	0.89
142_P	186_P	0.759	0.89
120_F	141_K	0.755	0.89
16_F	157_I	0.754	0.89
162_D	230_V	0.751	0.89
255_Y	337_K	0.743	0.88
243_A	276_T	0.741	0.88
63_R	67_Q	0.740	0.88
74_L	98_L	0.736	0.88
74_L	95_V	0.733	0.87
244_A	352_H	0.732	0.87
312_F	317_W	0.731	0.87
200_I	210_L	0.728	0.87
276_T	279_G	0.725	0.87
200_I	207_S	0.724	0.87
304_L	322_F	0.721	0.86
154_M	173_F	0.720	0.86
159_S	219_A	0.719	0.86
336_K	342_E	0.716	0.86
151_M	174_E	0.716	0.86
209_L	223_G	0.715	0.86
137_I	194_M	0.715	0.86
155_S	230_V	0.715	0.86
237_P	311_V	0.713	0.86
24_F	188_E	0.708	0.85
145_A	177_I	0.707	0.85
213_V	216_H	0.707	0.85
128_P	170_R	0.705	0.85
145_A	193_L	0.703	0.85
39_P	42_V	0.702	0.85
244_A	270_E	0.702	0.85
163_D	232_S	0.700	0.85
269_W	346_F	0.696	0.85
71_V	102_V	0.695	0.84
120_F	139_Y	0.692	0.84
100_S	104_E	0.689	0.84
118_K	141_K	0.689	0.84
175_D	179_A	0.688	0.84
181_I	186_P	0.683	0.83
68_F	99_Q	0.681	0.83
181_I	190_N	0.680	0.83
151_M	173_F	0.679	0.83
43_W	134_V	0.676	0.83
112_I	139_Y	0.672	0.82
36_D	61_F	0.672	0.82
77_A	99_Q	0.672	0.82
71_V	120_F	0.672	0.82
304_L	320_S	0.669	0.82
308_V	319_I	0.668	0.82
78_D	95_V	0.667	0.82
256_I	343_L	0.667	0.82
180_F	189_F	0.666	0.82
142_P	182_S	0.665	0.82
45_S	49_L	0.663	0.82
215_Q	293_N	0.662	0.81
128_P	178_R	0.661	0.81
250_E	326_V	0.658	0.81
87_E	353_Q	0.658	0.81
48_M	263_G	0.654	0.81
163_D	169_T	0.651	0.80
84_K	347_A	0.649	0.80
154_M	157_I	0.649	0.80
163_D	166_K	0.648	0.80
353_Q	357_K	0.647	0.80
44_V	85_A	0.646	0.80
87_E	347_A	0.645	0.80
155_S	228_L	0.645	0.80
239_I	309_E	0.643	0.80
44_V	101_A	0.641	0.79
265_L	314_H	0.640	0.79
352_H	355_I	0.639	0.79
113_V	126_V	0.633	0.79
150_V	198_A	0.631	0.78
259_R	263_G	0.631	0.78
312_F	350_V	0.631	0.78
262_K	266_A	0.629	0.78
199_L	202_T	0.629	0.78
162_D	168_K	0.628	0.78
22_S	26_R	0.628	0.78
47_V	126_V	0.628	0.78
264_L	317_W	0.627	0.78
81_K	85_A	0.627	0.78
305_Q	323_F	0.627	0.78
28_Q	188_E	0.626	0.78
137_I	188_E	0.623	0.77
80_E	346_F	0.622	0.77
35_E	137_I	0.620	0.77
64_F	123_L	0.620	0.77
56_T	350_V	0.620	0.77
186_P	192_G	0.619	0.77
158_L	177_I	0.617	0.77
102_V	113_V	0.616	0.77
19_D	22_S	0.614	0.76
68_F	82_V	0.614	0.76
95_V	99_Q	0.613	0.76
187_S	190_N	0.613	0.76
147_D	150_V	0.610	0.76
271_F	355_I	0.610	0.76
163_D	233_K	0.609	0.76
63_R	66_E	0.609	0.76
242_M	312_F	0.607	0.76
107_Q	110_G	0.604	0.75
270_E	352_H	0.604	0.75
227_E	230_V	0.603	0.75
300_D	325_K	0.601	0.75
228_L	231_K	0.601	0.75
33_W	54_V	0.599	0.75
338_V	344_E	0.598	0.75
265_L	352_H	0.598	0.75
71_V	106_K	0.597	0.74
159_S	225_E	0.596	0.74
194_M	269_W	0.596	0.74
145_A	151_M	0.595	0.74
113_V	135_L	0.594	0.74
354_K	358_M	0.593	0.74
244_A	265_L	0.592	0.74
79_E	96_R	0.592	0.74
150_V	199_L	0.590	0.74
93_S	266_A	0.590	0.74
136_S	144_P	0.590	0.74
24_F	137_I	0.590	0.74
101_A	120_F	0.589	0.73
206_P	225_E	0.587	0.73
319_I	352_H	0.586	0.73
129_Y	151_M	0.584	0.73
317_W	352_H	0.582	0.73
62_L	65_V	0.581	0.72
117_E	120_F	0.581	0.72
250_E	327_K	0.580	0.72
145_A	190_N	0.579	0.72
160_I	173_F	0.579	0.72
153_V	195_E	0.578	0.72
270_E	347_A	0.576	0.72
254_V	356_W	0.576	0.72
173_F	177_I	0.574	0.71
231_K	234_K	0.574	0.71
274_L	280_I	0.572	0.71
161_W	227_E	0.571	0.71
177_I	180_F	0.570	0.71
45_S	54_V	0.570	0.71
295_Y	299_A	0.569	0.71
109_Y	112_I	0.569	0.71
34_R	195_E	0.568	0.71
28_Q	129_Y	0.568	0.71
18_D	184_E	0.568	0.71
312_F	352_H	0.566	0.70
148_G	314_H	0.566	0.70
243_A	280_I	0.565	0.70
128_P	173_F	0.564	0.70
137_I	191_Q	0.562	0.70
294_E	297_I	0.562	0.70
250_E	325_K	0.561	0.70
187_S	193_L	0.560	0.70
291_L	299_A	0.560	0.70
148_G	203_P	0.559	0.70
206_P	217_C	0.558	0.69
154_M	176_A	0.558	0.69
76_D	107_Q	0.557	0.69
273_N	352_H	0.557	0.69
242_M	315_L	0.556	0.69
145_A	194_M	0.555	0.69
244_A	355_I	0.554	0.69
164_I	231_K	0.553	0.69
19_D	157_I	0.553	0.69
117_E	174_E	0.553	0.69
17_R	186_P	0.553	0.69
182_S	185_K	0.553	0.69
122_G	141_K	0.551	0.68
79_E	100_S	0.551	0.68
145_A	317_W	0.550	0.68
129_Y	195_E	0.550	0.68
291_L	294_E	0.548	0.68
297_I	301_I	0.548	0.68
302_S	305_Q	0.548	0.68
276_T	280_I	0.548	0.68
108_E	119_D	0.547	0.68
47_V	101_A	0.545	0.68
277_Q	281_K	0.544	0.67
189_F	195_E	0.543	0.67
317_W	351_S	0.538	0.67
59_P	63_R	0.538	0.67
129_Y	174_E	0.538	0.67
338_V	342_E	0.537	0.66
331_D	341_E	0.536	0.66
40_Y	45_S	0.535	0.66
132_G	182_S	0.535	0.66
42_V	47_V	0.534	0.66
105_V	111_G	0.533	0.66
60_Y	148_G	0.533	0.66
38_D	112_I	0.532	0.66
265_L	351_S	0.532	0.66
83_L	99_Q	0.531	0.66
300_D	327_K	0.529	0.65
289_A	293_N	0.527	0.65
186_P	189_F	0.526	0.65
104_E	107_Q	0.525	0.65
259_R	314_H	0.524	0.65
243_A	320_S	0.524	0.65
72_E	107_Q	0.524	0.65
26_R	108_E	0.523	0.64
301_I	305_Q	0.522	0.64
165_A	169_T	0.522	0.64
206_P	211_C	0.521	0.64
311_V	314_H	0.521	0.64
142_P	181_I	0.517	0.64
266_A	315_L	0.516	0.63
93_S	258_K	0.515	0.63
265_L	317_W	0.515	0.63
181_I	189_F	0.514	0.63
55_E	195_E	0.514	0.63
104_E	123_L	0.514	0.63
79_E	258_K	0.513	0.63
34_R	265_L	0.513	0.63
238_G	266_A	0.513	0.63
169_T	230_V	0.510	0.63
120_F	131_K	0.510	0.63
118_K	121_G	0.508	0.62
138_A	141_K	0.507	0.62
34_R	137_I	0.506	0.62
151_M	169_T	0.506	0.62
336_K	339_T	0.504	0.62
302_S	324_G	0.504	0.62
290_F	294_E	0.503	0.61
296_G	302_S	0.503	0.61
132_G	177_I	0.503	0.61
185_K	192_G	0.503	0.61
115_P	119_D	0.503	0.61
107_Q	340_K	0.502	0.61
163_D	317_W	0.502	0.61
53_R	202_T	0.500	0.61
244_A	273_N	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3fspA	1	0.9539	100	0.384	Contact Map
1kg2A	1	0.6043	100	0.536	Contact Map
3n5nX	1	0.7046	100	0.54	Contact Map
1keaA	2	0.5854	100	0.578	Contact Map
4unfA	1	0.5935	100	0.602	Contact Map
1ornA	1	0.5772	100	0.612	Contact Map
4uobA	1	0.5935	100	0.615	Contact Map
2abkA	1	0.5691	100	0.63	Contact Map
1pu6A	1	0.5122	100	0.722	Contact Map
3n0uA	1	0.5285	100	0.734	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0107 seconds.