YFIY - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFIY - Probable siderophore-binding lipoprotein YfiY

UniProt:	O31567	Sequences: MKKHISMLFVFLMAVMVLSACNSSESSSNSEVSSSKTRTVKHAMGTSDNIPANPKRIVVLTNEGTEALLALGIKPVGAVKSWKGDPWYDYLKDDMKGVKNVGLETEPNVEAIAELKPDLIIGNKVRQEKIYDQLNAIAPTVFAESLAGNWKDNLTLYANAVNKADKGKEVIADFDKRVSDLKNKLGDQTNKTVSVVRFLSGESRIYYTDSFPGIILDQLGFKRPEKQVELFKKQKDQFTFSTDSKESIPDMDADVLFYFTYKADNAKENEKWANQWTSSSLWKNLKAVKSGNAHEVDDVVWTTAGGIKAANYLLDDIETYFLKTK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	325 (286)
Sequences:	13700 (10892)
Seq/√Len:	644.0

ECOLI - FECB FEPB FHUD BTUF
BACSU - YFIY YHFQ YVRC YXEB FEUA FHUD YCLQ YFMC BTR
HALSA - BTUFA Q9HMF9 Q9HMG8 Q9HPB0 Q9HSB2
SULSO - Q97ZU2 Q980Z0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
155_T	168_K	4.106	1.00
252_D	286_K	3.992	1.00
158_A	167_G	3.990	1.00
151_K	175_D	3.814	1.00
163_K	166_K	3.431	1.00
177_R	315_D	3.201	1.00
159_N	164_A	3.139	1.00
286_K	290_S	3.108	1.00
59_V	65_T	2.905	1.00
155_T	171_I	2.711	1.00
179_S	183_N	2.682	1.00
166_K	169_E	2.650	1.00
168_K	172_A	2.568	1.00
216_L	221_F	2.545	1.00
172_A	176_K	2.540	1.00
111_A	114_E	2.442	1.00
247_S	250_D	2.387	1.00
58_V	112_I	2.227	1.00
42_H	47_S	2.212	1.00
192_T	222_K	2.174	1.00
57_I	161_V	2.104	1.00
68_L	161_V	2.101	1.00
175_D	179_S	2.061	1.00
176_K	180_D	2.058	1.00
277_T	291_G	2.005	1.00
56_R	76_V	1.991	1.00
213_G	217_D	1.971	1.00
73_I	161_V	1.966	1.00
67_A	154_L	1.959	1.00
254_D	286_K	1.943	1.00
180_D	184_K	1.941	1.00
274_N	278_S	1.913	1.00
133_Q	136_A	1.882	1.00
73_I	163_K	1.855	1.00
169_E	173_D	1.835	1.00
41_K	47_S	1.826	1.00
37_T	49_N	1.787	1.00
131_Y	135_N	1.782	1.00
39_T	49_N	1.782	1.00
121_I	157_Y	1.745	1.00
255_V	292_N	1.737	1.00
46_T	135_N	1.730	1.00
77_G	115_L	1.721	1.00
255_V	294_H	1.708	1.00
285_L	288_V	1.698	1.00
42_H	46_T	1.687	1.00
165_D	169_E	1.655	1.00
286_K	289_K	1.640	1.00
152_D	155_T	1.630	1.00
179_S	182_K	1.611	1.00
177_R	311_N	1.587	1.00
107_P	112_I	1.567	1.00
38_R	159_N	1.547	1.00
132_D	136_A	1.517	1.00
173_D	177_R	1.491	1.00
41_K	46_T	1.488	1.00
284_N	289_K	1.481	1.00
191_K	255_V	1.466	1.00
58_V	115_L	1.464	1.00
166_K	170_V	1.458	1.00
193_V	221_F	1.456	1.00
274_N	277_T	1.450	1.00
282_W	288_V	1.432	1.00
99_K	111_A	1.431	1.00
181_L	314_L	1.429	1.00
273_A	277_T	1.417	1.00
245_K	279_S	1.416	1.00
113_A	137_I	1.413	1.00
149_N	152_D	1.412	1.00
108_N	111_A	1.410	1.00
128_E	132_D	1.401	1.00
256_L	287_A	1.394	1.00
58_V	77_G	1.382	1.00
190_N	222_K	1.376	1.00
152_D	156_L	1.367	1.00
202_E	242_T	1.358	1.00
110_E	246_E	1.340	1.00
79_V	82_W	1.330	1.00
151_K	171_I	1.326	1.00
59_V	68_L	1.315	1.00
315_D	319_T	1.314	1.00
183_N	186_G	1.313	1.00
164_A	168_K	1.302	1.00
132_D	135_N	1.301	1.00
50_I	53_N	1.296	1.00
76_V	115_L	1.290	1.00
181_L	318_E	1.289	1.00
247_S	251_M	1.283	1.00
294_H	320_Y	1.282	1.00
71_L	163_K	1.278	1.00
141_V	160_A	1.274	1.00
176_K	179_S	1.268	1.00
122_G	142_F	1.257	1.00
177_R	180_D	1.257	1.00
54_P	118_D	1.251	1.00
165_D	168_K	1.249	1.00
127_Q	130_I	1.245	1.00
68_L	73_I	1.245	1.00
13_M	16_M	1.239	1.00
316_D	319_T	1.225	1.00
192_T	254_D	1.222	1.00
141_V	156_L	1.220	1.00
89_D	92_K	1.219	1.00
172_A	175_D	1.219	1.00
180_D	183_N	1.216	1.00
154_L	167_G	1.205	1.00
39_T	47_S	1.198	1.00
170_V	173_D	1.195	1.00
155_T	175_D	1.191	1.00
227_Q	251_M	1.191	1.00
156_L	159_N	1.184	1.00
88_Y	91_L	1.180	1.00
311_N	315_D	1.171	1.00
171_I	175_D	1.169	1.00
195_V	216_L	1.162	1.00
56_R	116_K	1.159	1.00
225_E	251_M	1.153	1.00
14_A	17_V	1.151	1.00
178_V	314_L	1.142	1.00
39_T	46_T	1.141	1.00
109_V	133_Q	1.140	1.00
184_K	318_E	1.135	1.00
119_L	141_V	1.134	1.00
55_K	118_D	1.130	1.00
182_K	218_Q	1.122	1.00
224_P	251_M	1.115	1.00
173_D	176_K	1.109	1.00
221_F	321_F	1.104	1.00
208_T	217_D	1.103	1.00
57_I	119_L	1.101	1.00
191_K	292_N	1.068	1.00
42_H	131_Y	1.068	1.00
130_I	133_Q	1.066	1.00
222_K	226_K	1.063	1.00
21_C	24_S	1.056	1.00
194_S	253_A	1.050	1.00
37_T	52_A	1.047	1.00
255_V	321_F	1.044	1.00
70_A	170_V	1.041	1.00
55_K	74_K	1.035	1.00
194_S	205_I	1.017	1.00
145_S	148_G	1.014	1.00
155_T	159_N	1.002	1.00
182_K	186_G	1.002	1.00
185_L	188_Q	0.996	1.00
69_L	95_M	0.990	1.00
282_W	285_L	0.977	1.00
178_V	182_K	0.970	1.00
36_K	162_N	0.969	1.00
50_I	139_P	0.969	1.00
225_E	228_V	0.966	1.00
146_L	149_N	0.962	1.00
37_T	53_N	0.947	1.00
257_F	317_I	0.945	1.00
194_S	197_R	0.943	1.00
224_P	227_Q	0.942	1.00
120_I	138_A	0.942	1.00
143_A	156_L	0.937	1.00
68_L	75_P	0.937	1.00
68_L	121_I	0.932	1.00
78_A	98_V	0.931	1.00
177_R	181_L	0.917	1.00
21_C	25_E	0.915	1.00
258_Y	295_E	0.913	1.00
167_G	171_I	0.911	1.00
214_I	218_Q	0.910	1.00
75_P	98_V	0.909	1.00
297_D	300_V	0.909	1.00
57_I	68_L	0.909	1.00
214_I	217_D	0.905	1.00
280_S	283_K	0.905	1.00
11_F	15_V	0.904	1.00
286_K	292_N	0.904	1.00
53_N	163_K	0.903	1.00
80_K	100_N	0.903	1.00
301_W	304_A	0.903	1.00
36_K	52_A	0.902	1.00
50_I	54_P	0.901	1.00
157_Y	161_V	0.897	1.00
196_V	279_S	0.889	1.00
288_V	293_A	0.889	1.00
156_L	160_A	0.888	1.00
37_T	51_P	0.887	1.00
16_M	19_S	0.884	1.00
158_A	171_I	0.877	1.00
44_M	142_F	0.876	1.00
53_N	162_N	0.874	1.00
67_A	157_Y	0.872	1.00
174_F	218_Q	0.871	1.00
93_D	96_K	0.871	1.00
275_Q	278_S	0.870	1.00
195_V	259_F	0.869	1.00
121_I	160_A	0.861	1.00
225_E	247_S	0.859	1.00
92_K	95_M	0.852	1.00
124_K	144_E	0.845	1.00
42_H	45_G	0.844	1.00
119_L	160_A	0.842	1.00
71_L	170_V	0.841	1.00
193_V	216_L	0.840	1.00
69_L	75_P	0.823	1.00
54_P	119_L	0.821	1.00
248_I	285_L	0.821	1.00
12_L	16_M	0.820	1.00
277_T	293_A	0.819	1.00
38_R	50_I	0.816	1.00
64_G	121_I	0.812	1.00
66_E	308_K	0.811	1.00
61_T	123_N	0.806	1.00
44_M	135_N	0.805	1.00
157_Y	160_A	0.801	1.00
117_P	120_I	0.800	1.00
52_A	55_K	0.793	1.00
223_R	227_Q	0.783	1.00
283_K	288_V	0.783	1.00
99_K	102_G	0.782	1.00
169_E	172_A	0.782	1.00
185_L	318_E	0.782	1.00
60_L	120_I	0.778	1.00
198_F	201_G	0.775	1.00
249_P	285_L	0.773	1.00
174_F	178_V	0.772	1.00
243_D	251_M	0.772	1.00
193_V	257_F	0.769	1.00
40_V	141_V	0.767	1.00
9_F	13_M	0.766	1.00
168_K	171_I	0.766	1.00
74_K	163_K	0.765	1.00
272_W	275_Q	0.764	1.00
36_K	53_N	0.763	1.00
316_D	320_Y	0.762	1.00
15_V	19_S	0.761	1.00
153_N	156_L	0.761	1.00
155_T	158_A	0.760	1.00
297_D	316_D	0.758	1.00
77_G	101_V	0.757	1.00
196_V	199_L	0.752	1.00
196_V	256_L	0.751	1.00
15_V	18_L	0.751	1.00
315_D	318_E	0.751	1.00
89_D	93_D	0.745	1.00
279_S	283_K	0.743	1.00
206_Y	240_F	0.743	1.00
314_L	318_E	0.739	1.00
151_K	155_T	0.737	1.00
71_L	161_V	0.737	1.00
135_N	140_T	0.736	1.00
151_K	178_V	0.735	1.00
249_P	284_N	0.734	1.00
71_L	158_A	0.734	1.00
91_L	95_M	0.733	1.00
170_V	174_F	0.733	1.00
70_A	154_L	0.730	1.00
139_P	142_F	0.729	1.00
215_I	314_L	0.729	1.00
59_V	75_P	0.728	1.00
177_R	312_Y	0.727	1.00
40_V	50_I	0.726	1.00
180_D	315_D	0.723	1.00
257_F	294_H	0.717	1.00
249_P	253_A	0.715	1.00
71_L	166_K	0.715	1.00
77_G	102_G	0.714	1.00
194_S	248_I	0.714	1.00
191_K	221_F	0.710	1.00
11_F	17_V	0.706	1.00
14_A	18_L	0.704	1.00
78_A	100_N	0.704	1.00
91_L	94_D	0.702	1.00
206_Y	210_S	0.701	1.00
196_V	201_G	0.701	1.00
194_S	198_F	0.701	1.00
244_S	247_S	0.697	1.00
10_V	13_M	0.697	1.00
103_L	106_E	0.696	1.00
90_Y	93_D	0.694	1.00
306_G	309_A	0.691	1.00
154_L	170_V	0.687	1.00
19_S	22_N	0.687	1.00
11_F	14_A	0.685	1.00
120_I	137_I	0.685	1.00
70_A	308_K	0.685	1.00
223_R	226_K	0.685	1.00
181_L	185_L	0.684	1.00
312_Y	316_D	0.681	1.00
208_T	228_V	0.681	1.00
205_I	225_E	0.678	1.00
10_V	14_A	0.678	1.00
72_G	163_K	0.677	1.00
210_S	213_G	0.675	1.00
56_R	118_D	0.673	1.00
184_K	187_D	0.671	1.00
20_A	24_S	0.670	1.00
101_V	115_L	0.663	1.00
66_E	306_G	0.663	1.00
177_R	318_E	0.662	1.00
178_V	218_Q	0.660	1.00
12_L	15_V	0.657	1.00
112_I	134_L	0.656	1.00
50_I	119_L	0.652	1.00
161_V	164_A	0.652	1.00
150_W	174_F	0.650	1.00
128_E	131_Y	0.648	1.00
129_K	132_D	0.648	1.00
273_A	295_E	0.644	1.00
72_G	166_K	0.643	1.00
58_V	117_P	0.642	1.00
71_L	167_G	0.642	1.00
308_K	312_Y	0.641	1.00
148_G	152_D	0.641	1.00
59_V	64_G	0.637	1.00
155_T	164_A	0.636	1.00
299_V	303_T	0.635	1.00
99_K	115_L	0.634	1.00
126_R	130_I	0.627	1.00
109_V	112_I	0.626	1.00
216_L	219_L	0.625	1.00
174_F	177_R	0.622	1.00
88_Y	92_K	0.621	1.00
61_T	64_G	0.620	1.00
258_Y	293_A	0.618	1.00
20_A	23_S	0.617	1.00
58_V	101_V	0.617	1.00
300_V	303_T	0.613	1.00
313_L	317_I	0.610	1.00
193_V	197_R	0.610	1.00
307_I	311_N	0.609	1.00
53_N	118_D	0.609	1.00
10_V	17_V	0.609	1.00
154_L	171_I	0.609	1.00
64_G	143_A	0.608	1.00
69_L	94_D	0.607	1.00
194_S	224_P	0.606	1.00
171_I	174_F	0.606	1.00
71_L	154_L	0.605	1.00
17_V	20_A	0.597	1.00
259_F	296_V	0.593	1.00
219_L	314_L	0.593	1.00
68_L	157_Y	0.592	1.00
196_V	205_I	0.590	1.00
50_I	160_A	0.589	1.00
317_I	321_F	0.589	1.00
95_M	98_V	0.588	1.00
109_V	137_I	0.586	1.00
43_A	156_L	0.586	1.00
260_T	295_E	0.584	1.00
253_A	256_L	0.584	1.00
221_F	255_V	0.580	1.00
298_D	301_W	0.579	1.00
192_T	255_V	0.578	1.00
311_N	314_L	0.578	1.00
62_N	81_S	0.577	1.00
245_K	282_W	0.577	1.00
36_K	51_P	0.576	1.00
301_W	313_L	0.572	1.00
193_V	196_V	0.569	1.00
208_T	226_K	0.567	1.00
54_P	161_V	0.566	1.00
58_V	120_I	0.564	1.00
261_Y	298_D	0.564	1.00
248_I	251_M	0.563	1.00
183_N	187_D	0.560	1.00
276_W	279_S	0.559	1.00
300_V	316_D	0.557	1.00
110_E	113_A	0.557	1.00
109_V	130_I	0.556	1.00
182_K	219_L	0.555	1.00
65_T	78_A	0.554	1.00
194_S	256_L	0.554	1.00
257_F	321_F	0.554	1.00
296_V	301_W	0.550	1.00
255_V	259_F	0.549	1.00
46_T	49_N	0.547	1.00
204_R	242_T	0.546	1.00
38_R	52_A	0.546	1.00
46_T	131_Y	0.545	1.00
181_L	184_K	0.544	1.00
243_D	248_I	0.544	1.00
207_Y	213_G	0.544	1.00
34_S	37_T	0.542	1.00
173_D	311_N	0.542	1.00
313_L	316_D	0.539	1.00
151_K	218_Q	0.537	1.00
195_V	212_P	0.536	0.99
12_L	17_V	0.535	0.99
209_D	213_G	0.535	0.99
285_L	289_K	0.534	0.99
197_R	200_S	0.534	0.99
210_S	240_F	0.533	0.99
208_T	227_Q	0.533	0.99
308_K	311_N	0.530	0.99
85_D	88_Y	0.530	0.99
145_S	149_N	0.529	0.99
18_L	21_C	0.529	0.99
75_P	78_A	0.528	0.99
219_L	321_F	0.528	0.99
279_S	282_W	0.527	0.99
182_K	185_L	0.527	0.99
64_G	67_A	0.527	0.99
151_K	174_F	0.527	0.99
37_T	50_I	0.526	0.99
249_P	281_L	0.522	0.99
175_D	178_V	0.520	0.99
64_G	157_Y	0.520	0.99
256_L	282_W	0.520	0.99
96_K	99_K	0.518	0.99
59_V	78_A	0.517	0.99
178_V	181_L	0.516	0.99
309_A	313_L	0.516	0.99
56_R	117_P	0.515	0.99
111_A	115_L	0.515	0.99
213_G	226_K	0.515	0.99
282_W	293_A	0.514	0.99
309_A	312_Y	0.512	0.99
129_K	133_Q	0.512	0.99
44_M	131_Y	0.510	0.99
71_L	157_Y	0.510	0.99
58_V	76_V	0.509	0.99
131_Y	142_F	0.507	0.99
38_R	54_P	0.505	0.99
44_M	47_S	0.504	0.99
51_P	139_P	0.503	0.99
67_A	70_A	0.503	0.99
210_S	239_T	0.502	0.99
94_D	97_G	0.501	0.99
206_Y	212_P	0.501	0.99
67_A	307_I	0.501	0.99
89_D	95_M	0.501	0.99
178_V	310_A	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4n01A	1	0.8615	100	0.207	Contact Map
4hn9A	1	0.8585	100	0.236	Contact Map
4mlzA	1	0.8462	100	0.24	Contact Map
3lhsA	1	0.8831	100	0.243	Contact Map
3tnyA	1	0.8615	100	0.25	Contact Map
4ovkA	1	0.8462	100	0.255	Contact Map
3tlkA	1	0.8646	100	0.256	Contact Map
4mo9A	1	0.8523	100	0.256	Contact Map
3mwfA	1	0.8738	100	0.266	Contact Map
3r5tA	1	0.8677	100	0.27	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0098 seconds.