ACOR - BACSU - GREMLIN Contacts

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ACOR - Acetoin dehydrogenase operon transcriptional activator AcoR

UniProt:	O31551	Sequences: MNSVPNDLQTWKRFVKDGVLDEARLRKRIAESWHRCKKAEVNPYLEKGPKVLQQTELDQQSKKHSFFLTTAKPYLEKLLPAIKEMEMMALLIDSDGVVLALDGHPRALYEAKRINFVEGACWTETAVGTNAIGTALHISEPVAIQGSEHYSIASHLWNCSAAPIHHEDGSLAGVIDISCPAAGAHPHMLGIATAIAYAAERELAAKSREKELELISRFGERAASSVPMVLCNTKQHIISASMPIRTSMPDWQGRHLYELKERGYSIENAVTIGDGGTCFYLSEQKKKKAFRFNGVIGQSGRSQAMLMHLERAAATDASVCLSGETGTGKEVAARALHENSERRHGPFVAVNCGAIPSDLIESELFGYAEGAFTGAKRNGYKGAFQKANQGTLFLDEIGEISHSMQVALLRVLQERKITPIGGTKEIPVDIRVIAATHCDLRELAENGKIREDLFYRLHVYPIELPPLRDRTEDIPDLFEYYKQKNHWPGDLPSDFCNVLKQWKWPGNIRELFNVFERLSIRFPDGRLRDESLPALLEAAGLPASSAEKKPAAAGVLTFREQIQKDMMIKALESAKGNVSQAAKISGIPRSTFYKRLKKFNLSAES	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	605 (567)
Sequences:	1742 (1367)
Seq/√Len:	57.4

ECOLI - DHAR YGEV HYFR FHLA RTCR NORR TYRR PRPR NTRC ATOC GLRR ZRAR
BACSU - ACOR YQIR ROCR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
324_E	468_R	5.736	1.00
574_A	584_I	5.213	1.00
385_Q	419_P	5.108	1.00
439_D	442_E	5.005	1.00
443_L	448_K	4.960	1.00
353_G	406_V	4.899	1.00
342_R	429_D	4.816	1.00
369_E	378_N	4.592	1.00
495_F	499_L	4.324	1.00
442_E	446_N	4.163	1.00
369_E	376_K	3.901	1.00
479_E	496_C	3.628	1.00
475_P	500_K	3.532	1.00
495_F	527_L	3.457	1.00
563_Q	595_R	3.358	1.00
587_I	592_F	3.166	1.00
574_A	581_A	3.148	1.00
31_E	138_I	3.125	1.00
438_C	443_L	3.105	1.00
232_N	236_H	3.075	1.00
357_S	403_S	3.061	1.00
330_E	410_R	3.053	1.00
353_G	399_E	2.984	1.00
564_K	568_I	2.976	1.00
484_K	512_F	2.970	1.00
413_Q	512_F	2.876	1.00
492_P	528_R	2.868	1.00
212_L	215_I	2.845	1.00
498_V	529_D	2.803	1.00
393_F	435_A	2.793	1.00
416_K	427_P	2.753	1.00
570_A	581_A	2.749	1.00
166_H	170_S	2.749	1.00
139_S	165_H	2.738	1.00
305_M	462_I	2.718	1.00
361_E	407_A	2.691	1.00
573_S	584_I	2.665	1.00
309_L	332_A	2.578	1.00
595_R	599_F	2.452	1.00
371_A	420_I	2.417	1.00
416_K	425_E	2.388	1.00
292_F	335_A	2.375	1.00
368_A	422_G	2.352	1.00
491_L	496_C	2.341	1.00
443_L	446_N	2.333	1.00
244_I	248_M	2.314	1.00
295_V	302_S	2.297	1.00
384_F	392_L	2.259	1.00
492_P	495_F	2.252	1.00
162_A	192_A	2.177	1.00
475_P	496_C	2.168	1.00
369_E	377_R	2.156	1.00
418_T	425_E	2.149	1.00
305_M	332_A	2.131	1.00
474_I	478_F	2.126	1.00
492_P	526_R	2.120	1.00
37_K	150_Y	2.119	1.00
518_L	527_L	2.113	1.00
159_C	176_D	2.073	1.00
29_I	144_I	2.057	1.00
314_A	341_E	2.056	1.00
567_M	592_F	2.020	1.00
398_G	436_T	2.013	1.00
334_R	338_E	1.967	1.00
388_N	429_D	1.961	1.00
32_S	129_T	1.959	1.00
311_R	523_P	1.913	1.00
333_A	347_F	1.904	1.00
227_P	241_S	1.895	1.00
324_E	466_P	1.887	1.00
342_R	430_I	1.884	1.00
384_F	428_V	1.868	1.00
360_I	404_M	1.864	1.00
491_L	515_F	1.857	1.00
376_K	380_Y	1.856	1.00
514_V	518_L	1.852	1.00
392_L	432_V	1.832	0.99
568_I	601_L	1.816	0.99
417_I	428_V	1.792	0.99
559_R	566_M	1.787	0.99
367_Y	379_G	1.784	0.99
494_D	529_D	1.775	0.99
560_E	598_K	1.770	0.99
570_A	574_A	1.766	0.99
317_A	520_I	1.763	0.99
445_E	451_E	1.742	0.99
159_C	178_S	1.739	0.99
475_P	478_F	1.735	0.99
412_L	432_V	1.735	0.99
444_A	447_G	1.730	0.99
562_I	566_M	1.714	0.99
422_G	425_E	1.684	0.99
442_E	445_E	1.666	0.99
422_G	426_I	1.647	0.99
60_Q	95_D	1.642	0.99
227_P	248_M	1.635	0.99
158_N	179_C	1.631	0.99
432_V	457_L	1.623	0.99
139_S	171_L	1.613	0.99
385_Q	426_I	1.595	0.99
596_L	601_L	1.590	0.98
467_L	511_L	1.586	0.98
571_L	581_A	1.578	0.98
56_E	59_Q	1.578	0.98
463_E	469_D	1.563	0.98
327_T	464_L	1.561	0.98
302_S	305_M	1.558	0.98
52_L	56_E	1.557	0.98
356_P	361_E	1.551	0.98
322_S	461_P	1.550	0.98
298_Q	476_D	1.534	0.98
241_S	244_I	1.530	0.98
131_A	161_A	1.527	0.98
441_R	535_L	1.520	0.98
384_F	430_I	1.519	0.98
571_L	578_V	1.515	0.98
319_V	336_L	1.509	0.98
35_R	124_E	1.498	0.98
64_H	94_S	1.497	0.98
482_K	519_S	1.494	0.98
383_A	386_K	1.486	0.98
322_S	436_T	1.484	0.98
124_E	129_T	1.474	0.98
566_M	570_A	1.467	0.97
392_L	428_V	1.467	0.97
559_R	595_R	1.458	0.97
388_N	428_V	1.455	0.97
362_S	372_F	1.441	0.97
240_A	244_I	1.437	0.97
57_L	118_E	1.436	0.97
578_V	592_F	1.433	0.97
389_Q	429_D	1.428	0.97
459_V	516_E	1.421	0.97
187_H	190_G	1.410	0.97
165_H	171_L	1.408	0.97
502_W	536_L	1.402	0.97
580_Q	583_K	1.394	0.97
349_A	410_R	1.392	0.96
103_G	111_A	1.392	0.96
567_M	595_R	1.391	0.96
330_E	414_E	1.386	0.96
320_C	434_A	1.380	0.96
136_L	174_V	1.356	0.96
371_A	375_A	1.352	0.96
228_M	241_S	1.345	0.96
357_S	361_E	1.340	0.96
306_L	332_A	1.336	0.96
313_A	431_R	1.312	0.95
533_P	536_L	1.305	0.95
130_N	134_T	1.304	0.95
497_N	501_Q	1.304	0.95
502_W	535_L	1.293	0.95
450_R	456_R	1.292	0.95
496_C	500_K	1.292	0.95
558_F	561_Q	1.290	0.95
215_I	218_F	1.289	0.95
452_D	456_R	1.285	0.94
577_N	589_R	1.283	0.94
491_L	527_L	1.283	0.94
119_G	128_G	1.278	0.94
214_L	218_F	1.271	0.94
489_G	519_S	1.269	0.94
360_I	407_A	1.257	0.94
139_S	170_S	1.254	0.94
119_G	149_H	1.248	0.94
133_G	159_C	1.246	0.94
440_L	449_I	1.228	0.93
197_Y	200_E	1.226	0.93
317_A	516_E	1.225	0.93
588_P	593_Y	1.215	0.93
122_W	133_G	1.214	0.93
36_C	39_A	1.211	0.93
565_D	569_K	1.208	0.92
78_L	195_I	1.206	0.92
267_E	271_T	1.203	0.92
216_S	221_R	1.203	0.92
494_D	528_R	1.201	0.92
568_I	572_E	1.200	0.92
502_W	505_P	1.189	0.92
313_A	336_L	1.184	0.92
92_I	98_V	1.181	0.92
471_T	474_I	1.178	0.91
459_V	513_N	1.175	0.91
260_K	263_G	1.174	0.91
65_S	69_T	1.172	0.91
128_G	131_A	1.171	0.91
579_S	583_K	1.168	0.91
312_A	384_F	1.160	0.91
398_G	438_C	1.159	0.91
218_F	222_A	1.157	0.91
97_V	121_C	1.144	0.90
76_E	102_D	1.139	0.90
266_I	269_A	1.134	0.90
292_F	295_V	1.134	0.90
410_R	414_E	1.129	0.90
518_L	531_S	1.126	0.90
351_N	354_A	1.122	0.89
478_F	515_F	1.120	0.89
267_E	273_G	1.116	0.89
387_A	430_I	1.112	0.89
330_E	349_A	1.111	0.89
263_G	273_G	1.108	0.89
463_E	466_P	1.104	0.89
208_R	211_E	1.101	0.88
559_R	562_I	1.099	0.88
130_N	133_G	1.096	0.88
381_K	423_T	1.094	0.88
306_L	310_E	1.091	0.88
450_R	509_R	1.087	0.88
72_K	100_A	1.084	0.88
358_D	361_E	1.083	0.88
335_A	339_N	1.082	0.88
332_A	464_L	1.081	0.88
312_A	460_Y	1.074	0.87
490_D	526_R	1.072	0.87
402_H	444_A	1.070	0.87
317_A	459_V	1.067	0.87
177_I	192_A	1.062	0.87
398_G	437_H	1.062	0.87
399_E	437_H	1.059	0.86
466_P	469_D	1.059	0.86
580_Q	584_I	1.057	0.86
129_T	159_C	1.054	0.86
27_K	31_E	1.054	0.86
34_H	38_K	1.052	0.86
563_Q	567_M	1.047	0.86
58_D	62_K	1.045	0.86
336_L	433_I	1.041	0.85
417_I	427_P	1.033	0.85
122_W	134_T	1.033	0.85
581_A	584_I	1.031	0.85
434_A	457_L	1.030	0.85
449_I	453_L	1.025	0.85
464_L	508_I	1.023	0.84
502_W	510_E	1.018	0.84
558_F	562_I	1.018	0.84
477_L	481_Y	1.008	0.84
458_H	513_N	1.007	0.83
116_F	157_W	1.002	0.83
384_F	411_V	1.001	0.83
31_E	34_H	1.000	0.83
292_F	309_L	0.998	0.83
291_R	294_G	0.996	0.83
219_G	222_A	0.996	0.83
367_Y	376_K	0.996	0.83
296_I	480_Y	0.995	0.83
579_S	589_R	0.994	0.83
340_S	345_G	0.992	0.83
273_G	278_C	0.992	0.83
523_P	531_S	0.992	0.83
295_V	331_V	0.991	0.83
53_Q	56_E	0.990	0.82
143_A	160_S	0.987	0.82
279_F	285_K	0.986	0.82
361_E	403_S	0.986	0.82
356_P	407_A	0.984	0.82
163_P	173_G	0.980	0.82
456_R	509_R	0.974	0.81
473_D	477_L	0.972	0.81
208_R	212_L	0.969	0.81
482_K	491_L	0.969	0.81
365_F	382_G	0.966	0.81
72_K	76_E	0.965	0.81
253_G	260_K	0.965	0.81
294_G	338_E	0.963	0.81
145_Q	158_N	0.960	0.80
489_G	525_G	0.956	0.80
237_I	259_L	0.956	0.80
124_E	130_N	0.951	0.80
217_R	222_A	0.950	0.80
563_Q	599_F	0.950	0.80
336_L	474_I	0.948	0.80
510_E	535_L	0.947	0.80
295_V	335_A	0.947	0.80
318_S	513_N	0.946	0.79
570_A	585_S	0.946	0.79
353_G	407_A	0.944	0.79
39_A	125_T	0.939	0.79
418_T	422_G	0.938	0.79
340_S	353_G	0.936	0.79
355_I	361_E	0.934	0.79
92_I	132_I	0.932	0.78
397_I	400_I	0.928	0.78
201_R	241_S	0.926	0.78
241_S	248_M	0.925	0.78
414_E	427_P	0.924	0.78
409_L	450_R	0.921	0.78
419_P	422_G	0.920	0.78
161_A	174_V	0.919	0.77
122_W	130_N	0.918	0.77
281_L	285_K	0.918	0.77
567_M	587_I	0.915	0.77
578_V	596_L	0.910	0.77
36_C	127_V	0.910	0.77
574_A	580_Q	0.909	0.77
493_S	497_N	0.907	0.77
386_K	422_G	0.906	0.76
337_H	391_T	0.904	0.76
30_A	34_H	0.903	0.76
569_K	573_S	0.897	0.76
357_S	399_E	0.894	0.75
466_P	551_A	0.892	0.75
592_F	595_R	0.891	0.75
315_T	520_I	0.889	0.75
59_Q	62_K	0.888	0.75
577_N	593_Y	0.885	0.75
149_H	159_C	0.885	0.75
305_M	309_L	0.884	0.75
415_R	427_P	0.884	0.75
589_R	593_Y	0.883	0.75
58_D	61_S	0.883	0.75
269_A	273_G	0.883	0.75
290_F	334_R	0.882	0.74
470_R	473_D	0.882	0.74
381_K	419_P	0.882	0.74
495_F	529_D	0.880	0.74
330_E	413_Q	0.879	0.74
198_A	312_A	0.878	0.74
92_I	127_V	0.877	0.74
296_I	303_Q	0.877	0.74
272_I	276_G	0.876	0.74
60_Q	97_V	0.876	0.74
316_D	431_R	0.876	0.74
576_G	589_R	0.873	0.74
409_L	452_D	0.873	0.74
410_R	452_D	0.872	0.74
395_D	435_A	0.870	0.73
471_T	475_P	0.870	0.73
107_A	157_W	0.870	0.73
333_A	391_T	0.870	0.73
532_L	537_E	0.870	0.73
452_D	509_R	0.870	0.73
293_N	310_E	0.869	0.73
145_Q	148_E	0.865	0.73
375_A	456_R	0.865	0.73
517_R	520_I	0.864	0.73
585_S	592_F	0.863	0.73
399_E	406_V	0.858	0.72
208_R	215_I	0.857	0.72
97_V	116_F	0.855	0.72
581_A	590_S	0.854	0.72
79_L	102_D	0.854	0.72
532_L	536_L	0.854	0.72
524_D	528_R	0.852	0.72
133_G	144_I	0.851	0.72
41_V	151_S	0.850	0.72
322_S	463_E	0.849	0.72
482_K	527_L	0.849	0.72
588_P	592_F	0.848	0.72
132_I	179_C	0.845	0.71
263_G	269_A	0.843	0.71
587_I	595_R	0.842	0.71
121_C	126_A	0.841	0.71
74_Y	202_E	0.838	0.71
84_E	104_H	0.838	0.71
122_W	149_H	0.833	0.70
90_L	101_L	0.833	0.70
367_Y	372_F	0.831	0.70
29_I	36_C	0.831	0.70
43_P	144_I	0.828	0.70
345_G	389_Q	0.828	0.70
495_F	531_S	0.827	0.70
321_L	592_F	0.826	0.70
308_H	521_R	0.825	0.69
162_A	196_A	0.824	0.69
135_A	142_V	0.823	0.69
441_R	445_E	0.821	0.69
103_G	131_A	0.821	0.69
151_S	154_S	0.820	0.69
191_I	196_A	0.820	0.69
264_Y	267_E	0.820	0.69
304_A	534_A	0.819	0.69
124_E	128_G	0.819	0.69
304_A	307_M	0.816	0.69
430_I	436_T	0.812	0.68
588_P	598_K	0.811	0.68
131_A	176_D	0.809	0.68
321_L	332_A	0.809	0.68
79_L	302_S	0.801	0.67
121_C	127_V	0.800	0.67
229_V	482_K	0.799	0.67
130_N	144_I	0.798	0.67
36_C	41_V	0.796	0.67
415_R	430_I	0.795	0.67
299_S	516_E	0.794	0.66
88_M	111_A	0.791	0.66
517_R	521_R	0.791	0.66
116_F	127_V	0.790	0.66
214_L	219_G	0.790	0.66
130_N	190_G	0.790	0.66
25_L	33_W	0.787	0.66
410_R	450_R	0.786	0.66
292_F	306_L	0.785	0.66
391_T	518_L	0.785	0.66
563_Q	592_F	0.783	0.65
395_D	456_R	0.783	0.65
61_S	68_L	0.782	0.65
145_Q	150_Y	0.781	0.65
499_L	511_L	0.781	0.65
212_L	218_F	0.780	0.65
212_L	216_S	0.779	0.65
561_Q	572_E	0.778	0.65
349_A	353_G	0.778	0.65
561_Q	565_D	0.776	0.65
359_L	450_R	0.776	0.65
292_F	391_T	0.775	0.65
269_A	272_I	0.773	0.64
224_S	228_M	0.773	0.64
581_A	592_F	0.772	0.64
516_E	520_I	0.769	0.64
45_L	434_A	0.767	0.64
351_N	359_L	0.766	0.64
107_A	111_A	0.766	0.64
36_C	154_S	0.765	0.64
133_G	178_S	0.763	0.63
131_A	135_A	0.763	0.63
563_Q	587_I	0.762	0.63
225_S	350_V	0.761	0.63
127_V	151_S	0.761	0.63
270_V	277_T	0.760	0.63
62_K	65_S	0.759	0.63
59_Q	63_K	0.757	0.63
471_T	503_K	0.756	0.63
208_R	217_R	0.756	0.63
556_L	570_A	0.755	0.63
261_E	267_E	0.755	0.63
410_R	456_R	0.754	0.62
578_V	590_S	0.753	0.62
263_G	274_D	0.752	0.62
255_H	259_L	0.751	0.62
78_L	89_A	0.751	0.62
263_G	266_I	0.750	0.62
495_F	518_L	0.748	0.62
245_R	252_Q	0.747	0.62
409_L	456_R	0.747	0.62
25_L	30_A	0.745	0.62
441_R	454_F	0.745	0.62
478_F	491_L	0.745	0.62
375_A	420_I	0.745	0.62
386_K	423_T	0.744	0.61
148_E	157_W	0.744	0.61
359_L	362_S	0.743	0.61
301_R	469_D	0.743	0.61
99_L	118_E	0.743	0.61
590_S	593_Y	0.742	0.61
396_E	452_D	0.742	0.61
374_G	450_R	0.741	0.61
150_Y	167_E	0.741	0.61
231_C	237_I	0.739	0.61
374_G	456_R	0.739	0.61
396_E	456_R	0.738	0.61
309_L	462_I	0.738	0.61
88_M	102_D	0.737	0.61
210_K	215_I	0.736	0.61
588_P	594_K	0.734	0.60
128_G	149_H	0.734	0.60
434_A	510_E	0.733	0.60
359_L	421_G	0.732	0.60
396_E	435_A	0.730	0.60
359_L	437_H	0.729	0.60
492_P	529_D	0.728	0.60
149_H	176_D	0.728	0.60
129_T	134_T	0.728	0.60
149_H	157_W	0.727	0.60
481_Y	512_F	0.727	0.60
71_A	199_A	0.726	0.60
383_A	418_T	0.726	0.60
478_F	518_L	0.726	0.60
36_C	151_S	0.725	0.59
86_E	104_H	0.725	0.59
522_F	531_S	0.725	0.59
442_E	501_Q	0.724	0.59
271_T	274_D	0.724	0.59
267_E	272_I	0.723	0.59
359_L	509_R	0.721	0.59
578_V	589_R	0.721	0.59
297_G	302_S	0.721	0.59
356_P	363_E	0.720	0.59
440_L	447_G	0.719	0.59
132_I	174_V	0.718	0.59
411_V	414_E	0.715	0.58
241_S	482_K	0.714	0.58
591_T	594_K	0.712	0.58
207_S	210_K	0.711	0.58
228_M	336_L	0.711	0.58
122_W	132_I	0.708	0.58
312_A	462_I	0.706	0.57
224_S	241_S	0.706	0.57
364_L	397_I	0.704	0.57
367_Y	435_A	0.704	0.57
267_E	270_V	0.703	0.57
336_L	383_A	0.703	0.57
362_S	509_R	0.701	0.57
291_R	338_E	0.700	0.57
367_Y	374_G	0.699	0.57
359_L	367_Y	0.698	0.57
227_P	247_S	0.697	0.56
590_S	594_K	0.697	0.56
410_R	509_R	0.694	0.56
54_Q	58_D	0.692	0.56
388_N	427_P	0.692	0.56
307_M	310_E	0.692	0.56
556_L	561_Q	0.692	0.56
82_I	98_V	0.691	0.56
96_G	136_L	0.690	0.56
576_G	596_L	0.690	0.56
265_S	273_G	0.689	0.56
209_E	212_L	0.689	0.56
359_L	365_F	0.689	0.56
354_A	363_E	0.688	0.55
243_P	246_T	0.688	0.55
116_F	122_W	0.685	0.55
163_P	594_K	0.684	0.55
411_V	417_I	0.682	0.55
115_N	127_V	0.682	0.55
354_A	361_E	0.680	0.55
52_L	55_T	0.679	0.54
363_E	367_Y	0.679	0.54
377_R	580_Q	0.679	0.54
185_H	334_R	0.677	0.54
116_F	154_S	0.677	0.54
160_S	510_E	0.677	0.54
99_L	130_N	0.676	0.54
144_I	149_H	0.674	0.54
30_A	43_P	0.673	0.54
131_A	149_H	0.673	0.54
265_S	270_V	0.670	0.53
559_R	567_M	0.669	0.53
374_G	396_E	0.668	0.53
111_A	114_I	0.668	0.53
136_L	437_H	0.667	0.53
133_G	136_L	0.667	0.53
260_K	264_Y	0.665	0.53
367_Y	456_R	0.665	0.53
368_A	443_L	0.664	0.53
26_R	148_E	0.662	0.53
160_S	187_H	0.662	0.53
124_E	149_H	0.660	0.52
67_F	172_A	0.660	0.52
227_P	559_R	0.660	0.52
354_A	439_D	0.660	0.52
445_E	596_L	0.659	0.52
278_C	555_V	0.658	0.52
128_G	159_C	0.658	0.52
460_Y	590_S	0.658	0.52
27_K	55_T	0.658	0.52
227_P	251_W	0.658	0.52
313_A	510_E	0.657	0.52
122_W	419_P	0.657	0.52
421_G	452_D	0.657	0.52
280_Y	285_K	0.654	0.52
382_G	456_R	0.654	0.52
282_S	285_K	0.654	0.52
437_H	456_R	0.654	0.52
295_V	336_L	0.654	0.52
130_N	159_C	0.653	0.52
413_Q	434_A	0.653	0.52
135_A	576_G	0.652	0.52
67_F	164_I	0.652	0.52
198_A	202_E	0.650	0.51
421_G	450_R	0.650	0.51
211_E	214_L	0.650	0.51
244_I	247_S	0.648	0.51
368_A	436_T	0.648	0.51
370_G	374_G	0.648	0.51
90_L	116_F	0.647	0.51
256_L	263_G	0.647	0.51
351_N	409_L	0.646	0.51
99_L	173_G	0.645	0.51
54_Q	61_S	0.644	0.51
262_R	272_I	0.644	0.51
481_Y	515_F	0.644	0.51
357_S	594_K	0.644	0.51
362_S	452_D	0.643	0.51
229_V	247_S	0.641	0.50
290_F	294_G	0.641	0.50
124_E	150_Y	0.638	0.50
575_K	596_L	0.637	0.50
421_G	456_R	0.635	0.50
87_M	91_L	0.635	0.50
397_I	417_I	0.635	0.50
98_V	101_L	0.634	0.50
180_P	380_Y	0.634	0.50
497_N	549_K	0.634	0.50
300_G	343_R	0.633	0.49
129_T	149_H	0.632	0.49
318_S	434_A	0.630	0.49
478_F	500_K	0.630	0.49
56_E	60_Q	0.630	0.49
578_V	587_I	0.630	0.49
295_V	306_L	0.630	0.49
269_A	277_T	0.629	0.49
300_G	471_T	0.628	0.49
129_T	176_D	0.628	0.49
351_N	373_T	0.627	0.49
362_S	456_R	0.627	0.49
164_I	199_A	0.625	0.49
359_L	452_D	0.625	0.49
119_G	129_T	0.623	0.48
60_Q	63_K	0.622	0.48
498_V	536_L	0.622	0.48
533_P	537_E	0.621	0.48
433_I	592_F	0.621	0.48
381_K	422_G	0.621	0.48
261_E	271_T	0.620	0.48
38_K	61_S	0.619	0.48
165_H	169_G	0.619	0.48
355_I	430_I	0.618	0.48
127_V	131_A	0.617	0.48
359_L	410_R	0.617	0.48
263_G	271_T	0.617	0.48
356_P	360_I	0.617	0.48
410_R	437_H	0.616	0.48
374_G	452_D	0.616	0.48
295_V	332_A	0.615	0.47
355_I	362_S	0.615	0.47
327_T	432_V	0.615	0.47
359_L	456_R	0.614	0.47
61_S	100_A	0.613	0.47
295_V	464_L	0.613	0.47
373_T	456_R	0.613	0.47
92_I	174_V	0.612	0.47
158_N	178_S	0.611	0.47
149_H	161_A	0.611	0.47
367_Y	393_F	0.611	0.47
132_I	178_S	0.611	0.47
243_P	247_S	0.611	0.47
299_S	459_V	0.611	0.47
264_Y	268_N	0.610	0.47
356_P	422_G	0.610	0.47
141_P	346_P	0.608	0.47
284_Q	466_P	0.607	0.47
564_K	599_F	0.605	0.46
367_Y	452_D	0.605	0.46
375_A	450_R	0.605	0.46
567_M	581_A	0.604	0.46
438_C	576_G	0.604	0.46
216_S	219_G	0.603	0.46
119_G	131_A	0.603	0.46
338_E	391_T	0.603	0.46
85_M	187_H	0.603	0.46
191_I	198_A	0.603	0.46
392_L	448_K	0.603	0.46
111_A	154_S	0.602	0.46
316_D	429_D	0.602	0.46
290_F	293_N	0.601	0.46
317_A	400_I	0.601	0.46
477_L	480_Y	0.601	0.46
565_D	568_I	0.601	0.46
383_A	404_M	0.601	0.46
27_K	30_A	0.600	0.46
325_T	459_V	0.600	0.46
135_A	138_I	0.600	0.46
261_E	265_S	0.599	0.46
325_T	520_I	0.599	0.46
490_D	515_F	0.599	0.46
351_N	450_R	0.599	0.46
29_I	82_I	0.598	0.46
571_L	596_L	0.598	0.46
302_S	306_L	0.597	0.45
303_Q	307_M	0.597	0.45
85_M	188_M	0.595	0.45
559_R	587_I	0.593	0.45
483_Q	501_Q	0.593	0.45
161_A	178_S	0.593	0.45
154_S	178_S	0.592	0.45
475_P	479_E	0.592	0.45
281_L	284_Q	0.591	0.45
370_G	396_E	0.591	0.45
312_A	589_R	0.591	0.45
280_Y	286_K	0.591	0.45
399_E	438_C	0.591	0.45
119_G	124_E	0.590	0.45
362_S	367_Y	0.590	0.45
396_E	437_H	0.587	0.44
60_Q	93_D	0.587	0.44
71_A	91_L	0.586	0.44
372_F	375_A	0.586	0.44
395_D	509_R	0.585	0.44
491_L	495_F	0.584	0.44
406_V	432_V	0.584	0.44
557_T	565_D	0.583	0.44
130_N	179_C	0.583	0.44
226_V	439_D	0.582	0.44
122_W	144_I	0.581	0.44
559_R	563_Q	0.581	0.44
133_G	157_W	0.581	0.44
37_K	41_V	0.580	0.44
373_T	396_E	0.578	0.43
309_L	339_N	0.577	0.43
119_G	122_W	0.577	0.43
213_E	221_R	0.577	0.43
241_S	593_Y	0.577	0.43
382_G	452_D	0.576	0.43
57_L	60_Q	0.576	0.43
348_V	386_K	0.575	0.43
215_I	222_A	0.573	0.43
568_I	596_L	0.573	0.43
270_V	275_G	0.572	0.43
60_Q	99_L	0.572	0.43
503_K	510_E	0.572	0.43
441_R	538_A	0.572	0.43
570_A	584_I	0.572	0.43
210_K	213_E	0.569	0.42
395_D	437_H	0.568	0.42
415_R	510_E	0.567	0.42
264_Y	272_I	0.566	0.42
478_F	499_L	0.566	0.42
331_V	508_I	0.565	0.42
94_S	574_A	0.565	0.42
304_A	308_H	0.564	0.42
367_Y	396_E	0.562	0.42
88_M	103_G	0.561	0.42
399_E	456_R	0.560	0.42
353_G	481_Y	0.560	0.42
38_K	66_F	0.560	0.42
441_R	534_A	0.558	0.41
514_V	517_R	0.558	0.41
76_E	123_T	0.557	0.41
57_L	148_E	0.557	0.41
191_I	195_I	0.557	0.41
242_M	245_R	0.556	0.41
128_G	161_A	0.556	0.41
269_A	275_G	0.555	0.41
209_E	213_E	0.554	0.41
64_H	67_F	0.554	0.41
370_G	395_D	0.553	0.41
129_T	161_A	0.553	0.41
260_K	267_E	0.553	0.41
298_Q	303_Q	0.552	0.41
437_H	509_R	0.552	0.41
572_E	600_N	0.551	0.41
154_S	157_W	0.550	0.40
566_M	595_R	0.549	0.40
229_V	244_I	0.547	0.40
265_S	269_A	0.547	0.40
351_N	363_E	0.547	0.40
473_D	482_K	0.546	0.40
415_R	429_D	0.546	0.40
211_E	215_I	0.545	0.40
208_R	216_S	0.544	0.40
122_W	179_C	0.544	0.40
359_L	373_T	0.544	0.40
262_R	266_I	0.544	0.40
37_K	596_L	0.544	0.40
171_L	315_T	0.544	0.40
210_K	216_S	0.543	0.40
126_A	433_I	0.543	0.40
499_L	514_V	0.543	0.40
570_A	587_I	0.543	0.40
160_S	202_E	0.543	0.40
111_A	132_I	0.542	0.40
39_A	43_P	0.542	0.40
371_A	445_E	0.542	0.40
312_A	342_R	0.541	0.39
130_N	149_H	0.540	0.39
393_F	396_E	0.540	0.39
296_I	419_P	0.540	0.39
264_Y	270_V	0.539	0.39
518_L	532_L	0.539	0.39
297_G	303_Q	0.538	0.39
499_L	536_L	0.537	0.39
497_N	572_E	0.536	0.39
349_A	373_T	0.536	0.39
133_G	158_N	0.535	0.39
419_P	426_I	0.534	0.39
34_H	37_K	0.534	0.39
228_M	232_N	0.534	0.39
149_H	589_R	0.534	0.39
189_L	578_V	0.533	0.39
583_K	597_K	0.532	0.39
356_P	359_L	0.531	0.38
359_L	372_F	0.530	0.38
367_Y	375_A	0.530	0.38
262_R	267_E	0.530	0.38
64_H	99_L	0.529	0.38
588_P	595_R	0.529	0.38
307_M	508_I	0.529	0.38
237_I	265_S	0.529	0.38
478_F	529_D	0.528	0.38
105_P	237_I	0.527	0.38
311_R	488_P	0.527	0.38
495_F	528_R	0.527	0.38
335_A	465_P	0.527	0.38
93_D	569_K	0.527	0.38
262_R	268_N	0.527	0.38
256_L	538_A	0.525	0.38
73_P	146_G	0.525	0.38
89_A	242_M	0.525	0.38
111_A	157_W	0.524	0.38
290_F	338_E	0.523	0.38
119_G	133_G	0.522	0.38
373_T	437_H	0.521	0.37
359_L	396_E	0.521	0.37
330_E	450_R	0.521	0.37
209_E	216_S	0.521	0.37
300_G	446_N	0.521	0.37
394_L	450_R	0.521	0.37
382_G	421_G	0.520	0.37
190_G	512_F	0.520	0.37
325_T	588_P	0.519	0.37
129_T	133_G	0.519	0.37
359_L	382_G	0.519	0.37
189_L	417_I	0.518	0.37
91_L	128_G	0.518	0.37
332_A	460_Y	0.517	0.37
363_E	396_E	0.517	0.37
196_A	200_E	0.517	0.37
256_L	259_L	0.516	0.37
325_T	450_R	0.516	0.37
284_Q	432_V	0.516	0.37
370_G	509_R	0.515	0.37
133_G	149_H	0.515	0.37
176_D	200_E	0.514	0.37
30_A	64_H	0.514	0.37
64_H	173_G	0.513	0.37
386_K	419_P	0.513	0.37
47_K	57_L	0.513	0.37
212_L	219_G	0.513	0.37
150_Y	253_G	0.512	0.36
71_A	159_C	0.512	0.36
321_L	392_L	0.511	0.36
445_E	553_A	0.511	0.36
342_R	345_G	0.509	0.36
255_H	262_R	0.508	0.36
360_I	401_S	0.508	0.36
351_N	455_Y	0.507	0.36
322_S	434_A	0.507	0.36
200_E	242_M	0.507	0.36
98_V	443_L	0.506	0.36
67_F	103_G	0.506	0.36
122_W	127_V	0.505	0.36
577_N	580_Q	0.505	0.36
129_T	178_S	0.505	0.36
211_E	216_S	0.505	0.36
137_H	420_I	0.505	0.36
375_A	452_D	0.504	0.36
529_D	532_L	0.503	0.36
515_F	570_A	0.503	0.36
75_L	175_I	0.503	0.36
399_E	415_R	0.503	0.36
107_A	154_S	0.503	0.36
478_F	496_C	0.502	0.35
442_E	492_P	0.502	0.35
267_E	276_G	0.502	0.35
437_H	450_R	0.501	0.35
382_G	396_E	0.501	0.35
488_P	491_L	0.500	0.35
325_T	456_R	0.500	0.35
29_I	38_K	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4l4uA	2	0.6331	100	0.432	Contact Map
3dzdA	2	0.6	100	0.57	Contact Map
1ojlA	3	0.4893	100	0.576	Contact Map
4fwgA	3	0.6281	100	0.701	Contact Map
4qhsA	3	0.395	100	0.749	Contact Map
4qosA	1	0.3884	100	0.752	Contact Map
1in4A	1	0.4364	100	0.768	Contact Map
1hqcA	1	0.4496	100	0.771	Contact Map
1r6bX	1	0.8083	100	0.772	Contact Map
1qvrA	3	0.7851	100	0.778	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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