GREMLIN Database
BGAL1 - Beta-galactosidase YesZ
UniProt: O31529 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 663 (641)
Sequences: 1734 (1256)
Seq/√Len: 49.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_E59_E6.5841.00
48_E51_K6.0291.00
388_E442_R5.8501.00
173_I192_F5.2791.00
533_T538_T5.2771.00
125_T234_C4.8231.00
126_A129_K4.4771.00
318_Q371_A4.3621.00
36_R39_E4.1731.00
90_E115_Y4.0501.00
58_K131_L3.9461.00
110_C155_C3.8101.00
46_E50_G3.7281.00
61_I137_L3.6481.00
110_C153_C3.5661.00
633_G657_I3.5541.00
161_L216_F3.5331.00
159_L197_Q3.3961.00
461_S496_K3.3481.00
535_S556_R3.3381.00
175_R179_A3.3351.00
49_E87_G3.2261.00
650_G653_E3.2111.00
463_F468_G3.2041.00
155_C158_C3.1971.00
65_Y134_L3.1391.00
293_W331_G3.1071.00
190_Q194_Q3.0671.00
460_A470_W3.0331.00
537_N555_E3.0211.00
427_I587_A2.9771.00
52_I122_I2.9611.00
58_K130_E2.9551.00
635_D638_T2.9361.00
153_C158_C2.9231.00
95_N99_E2.8591.00
65_Y136_G2.7691.00
22_Q25_D2.6991.00
88_R119_K2.6991.00
37_I61_I2.6211.00
322_V371_A2.5271.00
86_H194_Q2.5181.00
21_Q63_R2.4981.00
226_D258_N2.4971.00
464_A470_W2.4621.00
112_N220_M2.4551.00
172_V175_R2.4541.00
454_S486_H2.3991.00
498_S563_I2.3771.00
125_T129_K2.3631.00
555_E562_K2.3301.00
604_V617_V2.3271.00
542_V567_G2.2991.00
110_C158_C2.2971.00
462_A465_E2.2731.00
232_I236_S2.2371.00
438_L444_L2.2191.00
124_T231_I2.2171.00
117_R223_S2.1871.00
61_I73_M2.1721.00
121_A231_I2.1461.00
524_L568_S2.1421.00
31_G373_K2.1251.00
76_P123_I2.1111.00
601_G621_D2.0961.00
181_G342_S2.0541.00
226_D230_K2.0251.00
175_R178_E2.0161.00
61_I71_T2.0091.00
387_A428_H2.0061.00
422_I445_F2.0011.00
125_T235_Y1.9951.00
85_S103_H1.9951.00
539_L564_V1.9840.99
24_I67_S1.9600.99
538_T541_T1.9420.99
20_I63_R1.8620.99
500_I531_F1.8580.99
346_I483_H1.8490.99
424_N580_E1.8480.99
443_L586_Y1.8440.99
472_T498_S1.8380.99
219_E254_R1.8360.99
503_L532_D1.8300.99
28_R67_S1.8280.99
25_D29_E1.8240.99
24_I63_R1.8220.99
281_D419_Y1.8130.99
391_M431_L1.8060.99
446_T470_W1.8040.99
49_E88_R1.7900.99
24_I64_L1.7750.99
35_V64_L1.7720.99
233_R240_I1.7680.99
21_Q66_D1.7550.99
165_W212_M1.7500.99
649_V655_R1.7450.99
27_M337_W1.7280.99
319_A618_V1.7130.98
128_A232_I1.7090.98
458_K462_A1.6650.98
425_T584_R1.6640.98
137_L238_A1.6600.98
392_T456_F1.6450.98
621_D625_G1.6390.98
285_N431_L1.6310.98
536_G556_R1.6300.98
461_S465_E1.6220.98
425_T580_E1.5760.97
444_L463_F1.5600.97
251_D254_R1.5490.97
537_N557_N1.5460.97
582_L586_Y1.5260.97
65_Y71_T1.5240.97
497_T558_Y1.5240.97
52_I126_A1.5220.97
166_L176_L1.5170.97
44_V183_D1.5150.97
438_L456_F1.5110.97
241_T263_S1.5100.97
115_Y119_K1.5080.97
562_K589_E1.5060.97
624_G648_A1.5040.97
444_L468_G1.4900.96
173_I195_V1.4880.96
602_T649_V1.4840.96
86_H191_T1.4810.96
122_I126_A1.4770.96
164_D167_K1.4750.96
154_M197_Q1.4710.96
229_A258_N1.4640.96
165_W219_E1.4640.96
159_L163_H1.4630.96
54_V58_K1.4550.96
389_A427_I1.4490.96
115_Y118_K1.4330.95
232_I235_Y1.4320.95
446_T449_V1.4300.95
465_E558_Y1.4270.95
325_Y332_F1.4250.95
330_Q381_S1.4230.95
609_G612_G1.4190.95
264_Y280_C1.4170.95
585_H589_E1.4160.95
367_A371_A1.4160.95
452_L476_T1.4120.95
44_V188_T1.4070.95
173_I190_Q1.3980.95
608_I613_L1.3890.95
256_F286_L1.3880.95
25_D357_E1.3870.95
94_A100_I1.3870.95
46_E52_I1.3860.95
472_T563_I1.3860.95
208_S484_T1.3830.94
302_A308_S1.3800.94
465_E560_E1.3790.94
392_T446_T1.3790.94
245_S248_F1.3600.94
378_I381_S1.3480.94
137_L236_S1.3360.93
430_D441_Y1.3360.93
587_A592_I1.3330.93
469_I564_V1.3330.93
65_Y135_P1.3280.93
453_S456_F1.3260.93
222_A254_R1.3070.93
61_I136_G1.3050.93
64_L69_I1.3030.92
278_L431_L1.3000.92
62_A134_L1.3000.92
263_S295_L1.2970.92
626_S646_R1.2890.92
90_E113_N1.2850.92
21_Q59_E1.2840.92
86_H193_E1.2790.92
243_N265_D1.2740.92
624_G650_G1.2730.92
318_Q322_V1.2710.91
121_A227_E1.2710.91
392_T432_I1.2690.91
538_T551_A1.2620.91
62_A66_D1.2600.91
433_P436_A1.2530.91
305_L308_S1.2520.91
24_I69_I1.2400.90
287_K290_R1.2330.90
124_T227_E1.2300.90
139_G239_P1.2290.90
171_G174_E1.2270.90
371_A637_L1.2250.90
300_S361_G1.2250.90
34_V138_I1.2210.90
635_D639_H1.2190.90
414_L569_L1.2180.90
84_F91_R1.2120.89
553_L566_L1.2080.89
454_S458_K1.2080.89
602_T627_V1.2030.89
570_P578_M1.1960.89
362_Y366_L1.1950.89
390_A444_L1.1940.89
70_E138_I1.1940.89
84_F119_K1.1870.88
370_R374_E1.1820.88
169_R212_M1.1810.88
117_R227_E1.1790.88
410_R413_S1.1790.88
360_I504_F1.1740.88
38_G56_F1.1660.88
139_G261_F1.1660.88
77_T120_A1.1620.87
452_L494_L1.1610.87
542_V552_F1.1580.87
29_E366_L1.1570.87
12_P15_W1.1560.87
586_Y590_A1.1560.87
480_T484_T1.1550.87
571_S577_A1.1490.87
635_D655_R1.1430.86
139_G293_W1.1410.86
517_A520_I1.1410.86
261_F293_W1.1400.86
184_V340_Q1.1400.86
400_F450_P1.1390.86
501_K532_D1.1380.86
606_P613_L1.1360.86
176_L180_W1.1340.86
531_F567_G1.1330.86
418_F473_G1.1250.86
606_P615_W1.1230.85
420_E424_N1.1200.85
245_S264_Y1.1170.85
555_E564_V1.1130.85
367_A370_R1.1120.85
444_L460_A1.1110.85
522_A581_A1.1090.85
211_T451_Y1.1070.85
318_Q367_A1.1050.85
54_V131_L1.1050.85
222_A258_N1.1040.84
471_I566_L1.1030.84
443_L463_F1.1010.84
315_G364_N1.0970.84
143_D228_Q1.0970.84
557_N562_K1.0950.84
114_P157_T1.0950.84
167_K191_T1.0930.84
101_M202_P1.0900.84
439_D466_A1.0890.84
222_A255_M1.0860.83
466_A560_E1.0840.83
4_L372_R1.0840.83
495_E534_E1.0840.83
446_T472_T1.0840.83
161_L223_S1.0790.83
460_A497_T1.0780.83
76_P127_I1.0730.83
82_I86_H1.0620.82
213_Y217_S1.0600.82
516_K519_G1.0590.82
453_S481_C1.0570.82
129_K235_Y1.0530.82
647_L657_I1.0500.81
119_K122_I1.0490.81
59_E63_R1.0490.81
391_M422_I1.0450.81
629_L633_G1.0410.81
522_A578_M1.0340.80
161_L220_M1.0320.80
95_N101_M1.0320.80
219_E222_A1.0290.80
351_V365_V1.0290.80
281_D284_R1.0270.80
471_I586_Y1.0240.80
167_K192_F1.0240.80
61_I134_L1.0240.80
132_G236_S1.0210.79
107_Q123_I1.0190.79
39_E74_C1.0180.79
571_S578_M1.0120.79
142_L232_I1.0100.79
156_E196_P1.0100.79
229_A233_R1.0090.79
63_R67_S1.0080.79
462_A466_A1.0080.79
25_D67_S1.0060.78
146_F225_A1.0020.78
321_A368_V1.0020.78
635_D657_I1.0010.78
469_I590_A1.0000.78
129_K132_G0.9970.78
522_A571_S0.9960.78
370_R373_K0.9940.78
626_S648_A0.9940.78
304_S308_S0.9940.78
41_A44_V0.9910.77
500_I554_T0.9890.77
471_I582_L0.9860.77
160_R193_E0.9860.77
38_G76_P0.9830.77
634_T639_H0.9770.76
268_A320_E0.9770.76
168_N223_S0.9760.76
386_Q440_G0.9760.76
61_I64_L0.9710.76
128_A235_Y0.9700.76
419_Y429_R0.9680.76
169_R482_E0.9670.76
530_V546_P0.9650.75
94_A156_E0.9650.75
443_L590_A0.9640.75
449_V452_L0.9620.75
34_V333_C0.9620.75
354_A485_I0.9590.75
37_I71_T0.9590.75
20_I24_I0.9580.75
280_C324_S0.9580.75
424_N572_G0.9570.75
28_R367_A0.9570.75
6_H369_E0.9570.75
465_E557_N0.9550.75
513_N523_P0.9550.75
530_V550_H0.9530.75
363_Q366_L0.9520.74
82_I103_H0.9500.74
456_F459_K0.9480.74
471_I602_T0.9460.74
469_I562_K0.9420.74
253_E436_A0.9420.74
497_T563_I0.9410.74
91_R115_Y0.9410.74
379_I382_T0.9410.74
61_I65_Y0.9400.74
471_I583_V0.9400.74
22_Q26_I0.9390.73
71_T136_G0.9360.73
118_K122_I0.9240.72
265_D295_L0.9230.72
17_E20_I0.9220.72
307_S408_G0.9220.72
253_E431_L0.9170.72
80_P85_S0.9150.72
121_A125_T0.9130.71
426_G598_V0.9130.71
281_D327_L0.9130.71
516_K521_T0.9120.71
603_I620_M0.9120.71
13_E38_G0.9120.71
44_V53_D0.9080.71
46_E51_K0.9060.71
97_K200_P0.9060.71
617_V647_L0.9050.71
337_W352_L0.9030.71
41_A56_F0.9030.71
478_G505_T0.9020.70
461_S558_Y0.9020.70
520_I581_A0.8990.70
8_A36_R0.8980.70
34_V72_I0.8960.70
80_P109_A0.8940.70
27_M32_V0.8900.69
39_E141_Q0.8880.69
215_L396_R0.8870.69
29_E357_E0.8860.69
62_A71_T0.8860.69
501_K534_E0.8850.69
640_R655_R0.8840.69
624_G651_P0.8830.69
160_R163_H0.8810.69
179_A482_E0.8790.68
253_E433_P0.8780.68
226_D257_Q0.8770.68
299_P348_H0.8760.68
254_R257_Q0.8700.68
45_M127_I0.8630.67
450_P483_H0.8630.67
463_F469_I0.8620.67
132_G235_Y0.8620.67
24_I60_I0.8610.67
152_E214_Q0.8590.67
357_E362_Y0.8570.66
342_S484_T0.8550.66
72_I331_G0.8540.66
179_A480_T0.8540.66
463_F470_W0.8530.66
630_P633_G0.8530.66
182_T187_E0.8520.66
391_M445_F0.8510.66
167_K480_T0.8510.66
212_M482_E0.8490.66
168_N171_G0.8480.66
160_R164_D0.8470.66
391_M429_R0.8450.65
37_I74_C0.8430.65
647_L655_R0.8400.65
74_C141_Q0.8380.65
72_I293_W0.8370.65
210_R403_T0.8340.64
11_Y39_E0.8330.64
19_T356_G0.8330.64
435_G459_K0.8330.64
48_E194_Q0.8310.64
145_E296_E0.8310.64
189_Y209_L0.8310.64
464_A497_T0.8300.64
183_D342_S0.8290.64
318_Q637_L0.8280.64
433_P459_K0.8260.64
274_S419_Y0.8250.63
423_L428_H0.8240.63
424_N600_P0.8240.63
187_E206_H0.8220.63
244_G259_L0.8220.63
218_M222_A0.8220.63
467_G561_G0.8200.63
486_H493_E0.8190.63
65_Y68_G0.8190.63
583_V586_Y0.8170.63
443_L587_A0.8160.63
176_L195_V0.8160.63
297_T320_E0.8160.63
393_Y398_K0.8150.63
182_T189_Y0.8150.63
30_V362_Y0.8140.62
11_Y141_Q0.8130.62
45_M54_V0.8120.62
411_H415_V0.8120.62
443_L592_I0.8110.62
35_V69_I0.8100.62
464_A559_G0.8090.62
110_C157_T0.8090.62
278_L415_V0.8080.62
88_R115_Y0.8070.62
366_L370_R0.8070.62
44_V56_F0.8070.62
284_R430_D0.8060.62
455_E458_K0.8050.62
36_R141_Q0.8050.62
544_A548_A0.8010.61
257_Q435_G0.8000.61
38_G41_A0.8000.61
595_R604_V0.7990.61
442_R463_F0.7960.61
207_A343_G0.7940.61
165_W170_Y0.7920.60
261_F331_G0.7910.60
268_A297_T0.7900.60
297_T335_W0.7880.60
458_K461_S0.7870.60
632_S641_L0.7870.60
634_T638_T0.7870.60
13_E183_D0.7860.60
116_F143_D0.7860.60
40_F78_P0.7860.60
320_E620_M0.7840.60
112_N158_C0.7840.60
506_F547_G0.7800.59
9_C14_L0.7800.59
329_S332_F0.7790.59
225_A229_A0.7780.59
277_L605_A0.7780.59
492_G495_E0.7770.59
36_R74_C0.7740.59
457_I497_T0.7740.59
442_R466_A0.7740.59
380_L383_E0.7740.59
141_Q228_Q0.7710.58
170_Y212_M0.7700.58
37_I60_I0.7700.58
316_Y319_A0.7700.58
236_S239_P0.7690.58
184_V335_W0.7680.58
78_P109_A0.7670.58
125_T231_I0.7660.58
437_P440_G0.7650.58
360_I364_N0.7630.57
341_R487_T0.7620.57
317_L334_Y0.7550.57
302_A348_H0.7530.56
566_L570_P0.7510.56
111_T221_I0.7510.56
102_G199_G0.7500.56
62_A136_G0.7490.56
21_Q67_S0.7490.56
347_S478_G0.7490.56
554_T563_I0.7460.56
570_P582_L0.7450.56
121_A230_K0.7440.56
406_H409_L0.7430.55
313_A545_G0.7420.55
418_F566_L0.7400.55
454_S493_E0.7400.55
49_E122_I0.7390.55
275_A416_T0.7380.55
578_M582_L0.7350.55
76_P143_D0.7350.55
4_L194_Q0.7340.55
450_P479_R0.7310.54
269_S305_L0.7290.54
7_G10_Y0.7280.54
515_G543_E0.7280.54
14_L336_L0.7260.54
533_T536_G0.7250.54
164_D168_N0.7220.53
277_L281_D0.7220.53
48_E190_Q0.7220.53
531_F542_V0.7210.53
91_R277_L0.7210.53
564_V582_L0.7200.53
90_E157_T0.7200.53
29_E358_P0.7200.53
553_L586_Y0.7200.53
390_A441_Y0.7160.53
129_K133_R0.7150.53
143_D224_F0.7140.52
9_C335_W0.7140.52
422_I583_V0.7140.52
171_G175_R0.7120.52
82_I190_Q0.7110.52
183_D188_T0.7110.52
262_A286_L0.7100.52
111_T220_M0.7090.52
416_T419_Y0.7080.52
377_P614_V0.7080.52
472_T476_T0.7080.52
93_H151_A0.7080.52
28_R68_G0.7050.52
107_Q151_A0.7050.52
49_E119_K0.7040.51
33_N369_E0.7000.51
167_K173_I0.7000.51
564_V586_Y0.7000.51
91_R113_N0.6980.51
102_G197_Q0.6960.51
298_S320_E0.6930.50
58_K62_A0.6920.50
530_V547_G0.6920.50
11_Y74_C0.6920.50
49_E52_I0.6910.50
318_Q654_Y0.6900.50
507_P527_W0.6900.50
65_Y70_E0.6900.50
633_G655_R0.6890.50
93_H100_I0.6890.50
298_S305_L0.6870.50
157_T160_R0.6860.50
30_V369_E0.6860.50
181_G352_L0.6860.50
299_P349_G0.6850.50
404_E475_L0.6850.50
392_T429_R0.6850.50
303_A308_S0.6850.50
232_I240_I0.6840.49
230_K234_C0.6840.49
598_V604_V0.6830.49
171_G557_N0.6820.49
158_C213_Y0.6820.49
214_Q402_K0.6820.49
158_C220_M0.6820.49
167_K171_G0.6810.49
161_L164_D0.6800.49
220_M223_S0.6770.49
142_L225_A0.6750.49
93_H109_A0.6750.49
334_Y368_V0.6750.49
38_G127_I0.6740.48
425_T583_V0.6740.48
502_T529_A0.6730.48
318_Q653_E0.6730.48
18_E592_I0.6720.48
164_D193_E0.6720.48
339_Q353_S0.6710.48
32_V35_V0.6700.48
443_L471_I0.6700.48
16_D19_T0.6700.48
464_A563_I0.6680.48
288_Q440_G0.6660.48
24_I35_V0.6660.48
553_L582_L0.6650.47
107_Q116_F0.6640.47
226_D229_A0.6630.47
541_T597_D0.6620.47
139_G238_A0.6620.47
253_E285_N0.6610.47
355_W359_T0.6610.47
266_T319_A0.6600.47
20_I60_I0.6600.47
327_L603_I0.6590.47
584_R597_D0.6580.47
80_P108_H0.6580.47
120_A227_E0.6580.47
514_T528_S0.6580.47
87_G194_Q0.6580.47
618_V654_Y0.6570.47
144_N296_E0.6560.47
276_F279_N0.6560.47
425_T587_A0.6550.46
572_G580_E0.6550.46
268_A324_S0.6550.46
322_V375_I0.6530.46
301_Y391_M0.6530.46
545_G548_A0.6520.46
458_K588_E0.6510.46
111_T255_M0.6510.46
394_S397_A0.6510.46
577_A588_E0.6500.46
288_Q436_A0.6500.46
281_D285_N0.6500.46
318_Q368_V0.6500.46
141_Q312_H0.6480.46
438_L459_K0.6480.46
461_S497_T0.6480.46
319_A620_M0.6480.46
300_S320_E0.6480.46
141_Q336_L0.6480.46
499_G554_T0.6480.46
245_S252_N0.6470.46
291_P405_P0.6470.46
514_T524_L0.6460.46
325_Y372_R0.6450.45
316_Y320_E0.6450.45
282_L395_D0.6450.45
60_I63_R0.6450.45
365_V369_E0.6440.45
109_A151_A0.6440.45
121_A124_T0.6440.45
472_T531_F0.6430.45
48_E191_T0.6430.45
61_I238_A0.6420.45
7_G13_E0.6420.45
241_T261_F0.6410.45
243_N295_L0.6400.45
297_T324_S0.6400.45
389_A445_F0.6400.45
225_A259_L0.6390.45
386_Q389_A0.6390.45
244_G256_F0.6390.45
55_G130_E0.6380.45
252_N264_Y0.6370.45
191_T440_G0.6370.45
299_P303_A0.6370.45
497_T556_R0.6370.45
363_Q503_L0.6360.45
85_S92_M0.6340.44
109_A320_E0.6330.44
206_H344_S0.6310.44
540_G552_F0.6290.44
66_D164_D0.6280.44
377_P636_L0.6270.44
124_T224_F0.6270.44
524_L570_P0.6270.44
456_F460_A0.6260.44
41_A45_M0.6250.43
617_V657_I0.6250.43
230_K240_I0.6230.43
449_V456_F0.6230.43
535_S538_T0.6230.43
38_G45_M0.6220.43
587_A590_A0.6220.43
312_H336_L0.6210.43
396_R604_V0.6200.43
487_T490_G0.6200.43
536_G554_T0.6200.43
16_D20_I0.6200.43
6_H334_Y0.6200.43
163_H193_E0.6190.43
330_Q607_R0.6190.43
191_T195_V0.6190.43
389_A587_A0.6190.43
145_E267_Y0.6190.43
190_Q193_E0.6180.43
577_A640_R0.6180.43
615_W633_G0.6170.43
645_G648_A0.6170.43
113_N157_T0.6160.43
265_D335_W0.6160.43
11_Y14_L0.6160.43
396_R436_A0.6150.42
212_M215_L0.6150.42
417_H569_L0.6140.42
78_P107_Q0.6140.42
221_I250_V0.6140.42
417_H572_G0.6140.42
531_F565_M0.6130.42
8_A39_E0.6130.42
338_R356_G0.6130.42
634_T641_L0.6120.42
432_I444_L0.6120.42
346_I450_P0.6110.42
17_E21_Q0.6090.42
159_L196_P0.6080.42
84_F143_D0.6080.42
605_A620_M0.6080.42
172_V193_E0.6070.42
276_F323_S0.6070.42
297_T321_A0.6060.42
440_G465_E0.6050.41
72_I139_G0.6040.41
515_G544_A0.6040.41
34_V70_E0.6040.41
156_E159_L0.6030.41
604_V615_W0.6020.41
304_S348_H0.6020.41
460_A612_G0.6010.41
460_A502_T0.6010.41
398_K411_H0.6010.41
266_T323_S0.6010.41
156_E199_G0.5990.41
589_E627_V0.5990.41
90_E128_A0.5980.41
625_G628_T0.5980.41
187_E201_A0.5970.41
34_V139_G0.5970.41
8_A34_V0.5970.41
134_L137_L0.5960.41
8_A11_Y0.5960.41
196_P209_L0.5950.40
389_A592_I0.5950.40
607_R616_I0.5950.40
585_H641_L0.5950.40
230_K453_S0.5950.40
523_P571_S0.5940.40
105_S201_A0.5940.40
231_I235_Y0.5930.40
386_Q608_I0.5930.40
11_Y41_A0.5930.40
452_L456_F0.5920.40
415_V431_L0.5920.40
73_M127_I0.5910.40
116_F127_I0.5910.40
106_R185_W0.5900.40
293_W333_C0.5900.40
18_E623_K0.5900.40
584_R646_R0.5890.40
205_H210_R0.5890.40
603_I607_R0.5870.40
478_G490_G0.5870.40
191_T525_G0.5860.40
634_T646_R0.5850.39
414_L418_F0.5850.39
233_R237_D0.5850.39
39_E228_Q0.5840.39
11_Y36_R0.5830.39
39_E143_D0.5820.39
382_T608_I0.5800.39
10_Y23_D0.5800.39
336_L348_H0.5800.39
85_S107_Q0.5800.39
631_E646_R0.5790.39
551_A554_T0.5780.39
305_L310_Y0.5780.39
580_E584_R0.5780.39
25_D137_L0.5780.39
597_D628_T0.5780.39
84_F115_Y0.5770.39
434_E459_K0.5770.39
299_P339_Q0.5760.39
587_A591_V0.5750.39
374_E636_L0.5750.39
124_T146_F0.5750.39
225_A258_N0.5740.38
631_E641_L0.5730.38
8_A139_G0.5730.38
105_S203_F0.5730.38
9_C15_W0.5720.38
153_C250_V0.5720.38
116_F224_F0.5720.38
140_W260_D0.5720.38
22_Q356_G0.5710.38
121_A234_C0.5710.38
266_T324_S0.5710.38
66_D624_G0.5700.38
193_E584_R0.5700.38
418_F445_F0.5700.38
181_G206_H0.5700.38
257_Q624_G0.5690.38
472_T494_L0.5680.38
24_I71_T0.5680.38
322_V654_Y0.5670.38
446_T464_A0.5670.38
281_D429_R0.5670.38
303_A348_H0.5660.38
37_I62_A0.5650.38
56_F73_M0.5630.37
646_R653_E0.5630.37
194_Q214_Q0.5620.37
423_L426_G0.5610.37
189_Y194_Q0.5610.37
106_R345_E0.5600.37
43_S188_T0.5600.37
123_I228_Q0.5600.37
107_Q204_L0.5590.37
180_W209_L0.5590.37
64_L71_T0.5590.37
11_Y143_D0.5590.37
40_F104_G0.5590.37
42_W46_E0.5590.37
108_H187_E0.5590.37
233_R260_D0.5580.37
540_G553_L0.5580.37
56_F211_T0.5580.37
36_R336_L0.5580.37
36_R72_I0.5570.37
391_M610_E0.5570.37
350_S359_T0.5560.37
84_F90_E0.5560.37
375_I378_I0.5560.37
197_Q213_Y0.5560.37
283_W286_L0.5560.37
628_T646_R0.5550.37
339_Q348_H0.5540.36
421_R579_L0.5540.36
465_E537_N0.5530.36
64_L67_S0.5530.36
123_I127_I0.5520.36
144_N243_N0.5510.36
201_A206_H0.5500.36
330_Q380_L0.5500.36
446_T452_L0.5500.36
177_N345_E0.5490.36
395_D398_K0.5490.36
230_K258_N0.5490.36
118_K455_E0.5480.36
85_S91_R0.5480.36
591_V594_S0.5480.36
470_W563_I0.5480.36
467_G559_G0.5480.36
428_H605_A0.5470.36
214_Q249_S0.5470.36
393_Y415_V0.5460.36
172_V432_I0.5460.36
519_G541_T0.5460.36
189_Y195_V0.5450.36
581_A584_R0.5450.36
367_A637_L0.5450.36
217_S220_M0.5440.36
32_V337_W0.5430.35
317_L321_A0.5420.35
473_G592_I0.5420.35
414_L474_P0.5420.35
502_T531_F0.5400.35
310_Y530_V0.5400.35
567_G570_P0.5400.35
11_Y228_Q0.5400.35
15_W338_R0.5390.35
146_F224_F0.5390.35
496_K534_E0.5390.35
367_A650_G0.5380.35
363_Q458_K0.5380.35
477_G492_G0.5380.35
14_L340_Q0.5380.35
21_Q593_S0.5380.35
76_P228_Q0.5370.35
229_A240_I0.5370.35
531_F554_T0.5360.35
476_T491_L0.5360.35
374_E635_D0.5360.35
528_S544_A0.5360.35
421_R425_T0.5350.35
120_A224_F0.5350.35
266_T297_T0.5340.35
222_A259_L0.5340.35
101_M105_S0.5330.35
363_Q367_A0.5330.35
580_E583_V0.5330.35
90_E118_K0.5330.35
61_I132_G0.5320.34
322_V426_G0.5320.34
465_E647_L0.5320.34
581_A648_A0.5320.34
107_Q143_D0.5310.34
653_E657_I0.5310.34
517_A585_H0.5310.34
252_N283_W0.5300.34
8_A74_C0.5290.34
300_S346_I0.5290.34
115_Y157_T0.5280.34
41_A183_D0.5280.34
641_L657_I0.5270.34
213_Y249_S0.5270.34
268_A327_L0.5270.34
19_T22_Q0.5270.34
92_M182_T0.5260.34
385_V426_G0.5260.34
518_F634_T0.5260.34
351_V361_G0.5260.34
286_L421_R0.5260.34
80_P107_Q0.5250.34
68_G557_N0.5250.34
491_L495_E0.5240.34
246_V279_N0.5240.34
6_H317_L0.5230.34
33_N531_F0.5230.34
128_A140_W0.5230.34
463_F466_A0.5220.34
637_L640_R0.5220.34
49_E127_I0.5220.34
175_R577_A0.5220.34
223_S227_E0.5210.33
626_S650_G0.5210.33
222_A225_A0.5190.33
28_R172_V0.5190.33
232_I584_R0.5190.33
358_P362_Y0.5170.33
121_A392_T0.5170.33
391_M415_V0.5170.33
319_A323_S0.5170.33
39_E475_L0.5160.33
553_L564_V0.5160.33
548_A628_T0.5160.33
213_Y334_Y0.5150.33
553_L567_G0.5150.33
371_A374_E0.5150.33
435_G453_S0.5140.33
599_T604_V0.5140.33
462_A517_A0.5140.33
305_L309_A0.5140.33
232_I238_A0.5130.33
88_R91_R0.5130.33
385_V605_A0.5120.33
66_D272_N0.5120.33
225_A255_M0.5120.33
40_F338_R0.5110.33
24_I28_R0.5110.33
86_H103_H0.5110.33
541_T549_G0.5110.33
48_E164_D0.5090.32
187_E343_G0.5090.32
316_Y652_H0.5090.32
533_T556_R0.5080.32
250_V255_M0.5080.32
126_A445_F0.5080.32
254_R435_G0.5080.32
370_R458_K0.5080.32
218_M399_A0.5080.32
170_Y180_W0.5070.32
253_E395_D0.5070.32
56_F76_P0.5070.32
248_F280_C0.5070.32
489_C492_G0.5070.32
324_S329_S0.5060.32
562_K634_T0.5060.32
178_E523_P0.5050.32
434_E456_F0.5040.32
319_A652_H0.5040.32
26_I29_E0.5040.32
185_W345_E0.5040.32
414_L417_H0.5040.32
464_A467_G0.5030.32
552_F568_S0.5030.32
109_A143_D0.5030.32
361_G504_F0.5030.32
631_E638_T0.5020.32
448_F474_P0.5020.32
91_R224_F0.5020.32
91_R143_D0.5010.32
319_A334_Y0.5010.32
468_G561_G0.5010.32
327_L334_Y0.5010.32
250_V395_D0.5000.32
496_K608_I0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4uozA 3 0.9849 100 0.273 Contact Map
3ttyA 4 0.9804 100 0.273 Contact Map
4oifA 3 0.9789 100 0.277 Contact Map
1kwgA 3 0.9367 100 0.292 Contact Map
4d1iA 4 0.6968 100 0.673 Contact Map
3u7vA 3 0.6335 100 0.685 Contact Map
2zuvA 2 0.8627 100 0.699 Contact Map
1wdpA 1 0.5822 100 0.723 Contact Map
1fa2A 3 0.5837 100 0.742 Contact Map
4bq2A 4 0.5023 100 0.749 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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