BGAL1 - BACSU - GREMLIN Contacts

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BGAL1 - Beta-galactosidase YesZ

UniProt:	O31529	Sequences: MRKLYHGACYYPELWDEETIQQDIDIMREVGVNVVRIGEFAWSVMEPEEGKIDVGFFKEIIARLYDSGIETIMCTPTPTPPIWFSHGRPERMHANEKREIMGHGSRQHACTNNPYFRKKAAIITTAIAKELGRLPGLIGWQLDNEFKCHVAECMCETCLRLWHDWLKNRYGVIERLNEAWGTDVWSETYQTFEQVPQPGPAPFLHHASLRTMYQLFSMEMIASFADEQAKIIRCYSDAPITHNGSVMFSVDNERMFQNLDFASYDTYASQENASAFLLNCDLWRNLKQGRPFWILETSPSYAASLESSAYPHADGYLQAEAVSSYALGSQGFCYWLWRQQRSGSEISHGSVLSAWGEPTIGYQNVLAVERARKEIEPIILSTEPVQAEAAMTYSDRAKAFIKTEPHRGLRHRSLVTHFYERILNTGIHRDLIPEGAPLDGYRLLFTPFVPYLSSEFIKKASAFAEAGGIWITGPLTGGRTCEHTIHTDCGLGELEKTSGIKTLFTFPMNENVNTGKAFGITAPLGLWSAVFDTESGNTLGTVEAGPGAGHAFLTERNYGEGKIVMLGSLPSGKEGDAMLEALVRHYAEEAVISSRSDVTPGTIVAPRIGENGLVWIVVNMDGKGGSVTLPESGTDLLTHRLEKAGRLAVGPHEYRVIQFDNHS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	663 (641)
Sequences:	1734 (1256)
Seq/√Len:	49.6

BACSU - BGAL1 BGAL2
SULSO - Q97UK4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
17_E	59_E	6.584	1.00
48_E	51_K	6.029	1.00
388_E	442_R	5.850	1.00
173_I	192_F	5.279	1.00
533_T	538_T	5.277	1.00
125_T	234_C	4.823	1.00
126_A	129_K	4.477	1.00
318_Q	371_A	4.362	1.00
36_R	39_E	4.173	1.00
90_E	115_Y	4.050	1.00
58_K	131_L	3.946	1.00
110_C	155_C	3.810	1.00
46_E	50_G	3.728	1.00
61_I	137_L	3.648	1.00
110_C	153_C	3.566	1.00
633_G	657_I	3.554	1.00
161_L	216_F	3.533	1.00
159_L	197_Q	3.396	1.00
461_S	496_K	3.348	1.00
535_S	556_R	3.338	1.00
175_R	179_A	3.335	1.00
49_E	87_G	3.226	1.00
650_G	653_E	3.211	1.00
463_F	468_G	3.204	1.00
155_C	158_C	3.197	1.00
65_Y	134_L	3.139	1.00
293_W	331_G	3.107	1.00
190_Q	194_Q	3.067	1.00
460_A	470_W	3.033	1.00
537_N	555_E	3.021	1.00
427_I	587_A	2.977	1.00
52_I	122_I	2.961	1.00
58_K	130_E	2.955	1.00
635_D	638_T	2.936	1.00
153_C	158_C	2.923	1.00
95_N	99_E	2.859	1.00
65_Y	136_G	2.769	1.00
22_Q	25_D	2.699	1.00
88_R	119_K	2.699	1.00
37_I	61_I	2.621	1.00
322_V	371_A	2.527	1.00
86_H	194_Q	2.518	1.00
21_Q	63_R	2.498	1.00
226_D	258_N	2.497	1.00
464_A	470_W	2.462	1.00
112_N	220_M	2.455	1.00
172_V	175_R	2.454	1.00
454_S	486_H	2.399	1.00
498_S	563_I	2.377	1.00
125_T	129_K	2.363	1.00
555_E	562_K	2.330	1.00
604_V	617_V	2.327	1.00
542_V	567_G	2.299	1.00
110_C	158_C	2.297	1.00
462_A	465_E	2.273	1.00
232_I	236_S	2.237	1.00
438_L	444_L	2.219	1.00
124_T	231_I	2.217	1.00
117_R	223_S	2.187	1.00
61_I	73_M	2.172	1.00
121_A	231_I	2.146	1.00
524_L	568_S	2.142	1.00
31_G	373_K	2.125	1.00
76_P	123_I	2.111	1.00
601_G	621_D	2.096	1.00
181_G	342_S	2.054	1.00
226_D	230_K	2.025	1.00
175_R	178_E	2.016	1.00
61_I	71_T	2.009	1.00
387_A	428_H	2.006	1.00
422_I	445_F	2.001	1.00
125_T	235_Y	1.995	1.00
85_S	103_H	1.995	1.00
539_L	564_V	1.984	0.99
24_I	67_S	1.960	0.99
538_T	541_T	1.942	0.99
20_I	63_R	1.862	0.99
500_I	531_F	1.858	0.99
346_I	483_H	1.849	0.99
424_N	580_E	1.848	0.99
443_L	586_Y	1.844	0.99
472_T	498_S	1.838	0.99
219_E	254_R	1.836	0.99
503_L	532_D	1.830	0.99
28_R	67_S	1.828	0.99
25_D	29_E	1.824	0.99
24_I	63_R	1.822	0.99
281_D	419_Y	1.813	0.99
391_M	431_L	1.806	0.99
446_T	470_W	1.804	0.99
49_E	88_R	1.790	0.99
24_I	64_L	1.775	0.99
35_V	64_L	1.772	0.99
233_R	240_I	1.768	0.99
21_Q	66_D	1.755	0.99
165_W	212_M	1.750	0.99
649_V	655_R	1.745	0.99
27_M	337_W	1.728	0.99
319_A	618_V	1.713	0.98
128_A	232_I	1.709	0.98
458_K	462_A	1.665	0.98
425_T	584_R	1.664	0.98
137_L	238_A	1.660	0.98
392_T	456_F	1.645	0.98
621_D	625_G	1.639	0.98
285_N	431_L	1.631	0.98
536_G	556_R	1.630	0.98
461_S	465_E	1.622	0.98
425_T	580_E	1.576	0.97
444_L	463_F	1.560	0.97
251_D	254_R	1.549	0.97
537_N	557_N	1.546	0.97
582_L	586_Y	1.526	0.97
65_Y	71_T	1.524	0.97
497_T	558_Y	1.524	0.97
52_I	126_A	1.522	0.97
166_L	176_L	1.517	0.97
44_V	183_D	1.515	0.97
438_L	456_F	1.511	0.97
241_T	263_S	1.510	0.97
115_Y	119_K	1.508	0.97
562_K	589_E	1.506	0.97
624_G	648_A	1.504	0.97
444_L	468_G	1.490	0.96
173_I	195_V	1.488	0.96
602_T	649_V	1.484	0.96
86_H	191_T	1.481	0.96
122_I	126_A	1.477	0.96
164_D	167_K	1.475	0.96
154_M	197_Q	1.471	0.96
229_A	258_N	1.464	0.96
165_W	219_E	1.464	0.96
159_L	163_H	1.463	0.96
54_V	58_K	1.455	0.96
389_A	427_I	1.449	0.96
115_Y	118_K	1.433	0.95
232_I	235_Y	1.432	0.95
446_T	449_V	1.430	0.95
465_E	558_Y	1.427	0.95
325_Y	332_F	1.425	0.95
330_Q	381_S	1.423	0.95
609_G	612_G	1.419	0.95
264_Y	280_C	1.417	0.95
585_H	589_E	1.416	0.95
367_A	371_A	1.416	0.95
452_L	476_T	1.412	0.95
44_V	188_T	1.407	0.95
173_I	190_Q	1.398	0.95
608_I	613_L	1.389	0.95
256_F	286_L	1.388	0.95
25_D	357_E	1.387	0.95
94_A	100_I	1.387	0.95
46_E	52_I	1.386	0.95
472_T	563_I	1.386	0.95
208_S	484_T	1.383	0.94
302_A	308_S	1.380	0.94
465_E	560_E	1.379	0.94
392_T	446_T	1.379	0.94
245_S	248_F	1.360	0.94
378_I	381_S	1.348	0.94
137_L	236_S	1.336	0.93
430_D	441_Y	1.336	0.93
587_A	592_I	1.333	0.93
469_I	564_V	1.333	0.93
65_Y	135_P	1.328	0.93
453_S	456_F	1.326	0.93
222_A	254_R	1.307	0.93
61_I	136_G	1.305	0.93
64_L	69_I	1.303	0.92
278_L	431_L	1.300	0.92
62_A	134_L	1.300	0.92
263_S	295_L	1.297	0.92
626_S	646_R	1.289	0.92
90_E	113_N	1.285	0.92
21_Q	59_E	1.284	0.92
86_H	193_E	1.279	0.92
243_N	265_D	1.274	0.92
624_G	650_G	1.273	0.92
318_Q	322_V	1.271	0.91
121_A	227_E	1.271	0.91
392_T	432_I	1.269	0.91
538_T	551_A	1.262	0.91
62_A	66_D	1.260	0.91
433_P	436_A	1.253	0.91
305_L	308_S	1.252	0.91
24_I	69_I	1.240	0.90
287_K	290_R	1.233	0.90
124_T	227_E	1.230	0.90
139_G	239_P	1.229	0.90
171_G	174_E	1.227	0.90
371_A	637_L	1.225	0.90
300_S	361_G	1.225	0.90
34_V	138_I	1.221	0.90
635_D	639_H	1.219	0.90
414_L	569_L	1.218	0.90
84_F	91_R	1.212	0.89
553_L	566_L	1.208	0.89
454_S	458_K	1.208	0.89
602_T	627_V	1.203	0.89
570_P	578_M	1.196	0.89
362_Y	366_L	1.195	0.89
390_A	444_L	1.194	0.89
70_E	138_I	1.194	0.89
84_F	119_K	1.187	0.88
370_R	374_E	1.182	0.88
169_R	212_M	1.181	0.88
117_R	227_E	1.179	0.88
410_R	413_S	1.179	0.88
360_I	504_F	1.174	0.88
38_G	56_F	1.166	0.88
139_G	261_F	1.166	0.88
77_T	120_A	1.162	0.87
452_L	494_L	1.161	0.87
542_V	552_F	1.158	0.87
29_E	366_L	1.157	0.87
12_P	15_W	1.156	0.87
586_Y	590_A	1.156	0.87
480_T	484_T	1.155	0.87
571_S	577_A	1.149	0.87
635_D	655_R	1.143	0.86
139_G	293_W	1.141	0.86
517_A	520_I	1.141	0.86
261_F	293_W	1.140	0.86
184_V	340_Q	1.140	0.86
400_F	450_P	1.139	0.86
501_K	532_D	1.138	0.86
606_P	613_L	1.136	0.86
176_L	180_W	1.134	0.86
531_F	567_G	1.133	0.86
418_F	473_G	1.125	0.86
606_P	615_W	1.123	0.85
420_E	424_N	1.120	0.85
245_S	264_Y	1.117	0.85
555_E	564_V	1.113	0.85
367_A	370_R	1.112	0.85
444_L	460_A	1.111	0.85
522_A	581_A	1.109	0.85
211_T	451_Y	1.107	0.85
318_Q	367_A	1.105	0.85
54_V	131_L	1.105	0.85
222_A	258_N	1.104	0.84
471_I	566_L	1.103	0.84
443_L	463_F	1.101	0.84
315_G	364_N	1.097	0.84
143_D	228_Q	1.097	0.84
557_N	562_K	1.095	0.84
114_P	157_T	1.095	0.84
167_K	191_T	1.093	0.84
101_M	202_P	1.090	0.84
439_D	466_A	1.089	0.84
222_A	255_M	1.086	0.83
466_A	560_E	1.084	0.83
4_L	372_R	1.084	0.83
495_E	534_E	1.084	0.83
446_T	472_T	1.084	0.83
161_L	223_S	1.079	0.83
460_A	497_T	1.078	0.83
76_P	127_I	1.073	0.83
82_I	86_H	1.062	0.82
213_Y	217_S	1.060	0.82
516_K	519_G	1.059	0.82
453_S	481_C	1.057	0.82
129_K	235_Y	1.053	0.82
647_L	657_I	1.050	0.81
119_K	122_I	1.049	0.81
59_E	63_R	1.049	0.81
391_M	422_I	1.045	0.81
629_L	633_G	1.041	0.81
522_A	578_M	1.034	0.80
161_L	220_M	1.032	0.80
95_N	101_M	1.032	0.80
219_E	222_A	1.029	0.80
351_V	365_V	1.029	0.80
281_D	284_R	1.027	0.80
471_I	586_Y	1.024	0.80
167_K	192_F	1.024	0.80
61_I	134_L	1.024	0.80
132_G	236_S	1.021	0.79
107_Q	123_I	1.019	0.79
39_E	74_C	1.018	0.79
571_S	578_M	1.012	0.79
142_L	232_I	1.010	0.79
156_E	196_P	1.010	0.79
229_A	233_R	1.009	0.79
63_R	67_S	1.008	0.79
462_A	466_A	1.008	0.79
25_D	67_S	1.006	0.78
146_F	225_A	1.002	0.78
321_A	368_V	1.002	0.78
635_D	657_I	1.001	0.78
469_I	590_A	1.000	0.78
129_K	132_G	0.997	0.78
522_A	571_S	0.996	0.78
370_R	373_K	0.994	0.78
626_S	648_A	0.994	0.78
304_S	308_S	0.994	0.78
41_A	44_V	0.991	0.77
500_I	554_T	0.989	0.77
471_I	582_L	0.986	0.77
160_R	193_E	0.986	0.77
38_G	76_P	0.983	0.77
634_T	639_H	0.977	0.76
268_A	320_E	0.977	0.76
168_N	223_S	0.976	0.76
386_Q	440_G	0.976	0.76
61_I	64_L	0.971	0.76
128_A	235_Y	0.970	0.76
419_Y	429_R	0.968	0.76
169_R	482_E	0.967	0.76
530_V	546_P	0.965	0.75
94_A	156_E	0.965	0.75
443_L	590_A	0.964	0.75
449_V	452_L	0.962	0.75
34_V	333_C	0.962	0.75
354_A	485_I	0.959	0.75
37_I	71_T	0.959	0.75
20_I	24_I	0.958	0.75
280_C	324_S	0.958	0.75
424_N	572_G	0.957	0.75
28_R	367_A	0.957	0.75
6_H	369_E	0.957	0.75
465_E	557_N	0.955	0.75
513_N	523_P	0.955	0.75
530_V	550_H	0.953	0.75
363_Q	366_L	0.952	0.74
82_I	103_H	0.950	0.74
456_F	459_K	0.948	0.74
471_I	602_T	0.946	0.74
469_I	562_K	0.942	0.74
253_E	436_A	0.942	0.74
497_T	563_I	0.941	0.74
91_R	115_Y	0.941	0.74
379_I	382_T	0.941	0.74
61_I	65_Y	0.940	0.74
471_I	583_V	0.940	0.74
22_Q	26_I	0.939	0.73
71_T	136_G	0.936	0.73
118_K	122_I	0.924	0.72
265_D	295_L	0.923	0.72
17_E	20_I	0.922	0.72
307_S	408_G	0.922	0.72
253_E	431_L	0.917	0.72
80_P	85_S	0.915	0.72
121_A	125_T	0.913	0.71
426_G	598_V	0.913	0.71
281_D	327_L	0.913	0.71
516_K	521_T	0.912	0.71
603_I	620_M	0.912	0.71
13_E	38_G	0.912	0.71
44_V	53_D	0.908	0.71
46_E	51_K	0.906	0.71
97_K	200_P	0.906	0.71
617_V	647_L	0.905	0.71
337_W	352_L	0.903	0.71
41_A	56_F	0.903	0.71
478_G	505_T	0.902	0.70
461_S	558_Y	0.902	0.70
520_I	581_A	0.899	0.70
8_A	36_R	0.898	0.70
34_V	72_I	0.896	0.70
80_P	109_A	0.894	0.70
27_M	32_V	0.890	0.69
39_E	141_Q	0.888	0.69
215_L	396_R	0.887	0.69
29_E	357_E	0.886	0.69
62_A	71_T	0.886	0.69
501_K	534_E	0.885	0.69
640_R	655_R	0.884	0.69
624_G	651_P	0.883	0.69
160_R	163_H	0.881	0.69
179_A	482_E	0.879	0.68
253_E	433_P	0.878	0.68
226_D	257_Q	0.877	0.68
299_P	348_H	0.876	0.68
254_R	257_Q	0.870	0.68
45_M	127_I	0.863	0.67
450_P	483_H	0.863	0.67
463_F	469_I	0.862	0.67
132_G	235_Y	0.862	0.67
24_I	60_I	0.861	0.67
152_E	214_Q	0.859	0.67
357_E	362_Y	0.857	0.66
342_S	484_T	0.855	0.66
72_I	331_G	0.854	0.66
179_A	480_T	0.854	0.66
463_F	470_W	0.853	0.66
630_P	633_G	0.853	0.66
182_T	187_E	0.852	0.66
391_M	445_F	0.851	0.66
167_K	480_T	0.851	0.66
212_M	482_E	0.849	0.66
168_N	171_G	0.848	0.66
160_R	164_D	0.847	0.66
391_M	429_R	0.845	0.65
37_I	74_C	0.843	0.65
647_L	655_R	0.840	0.65
74_C	141_Q	0.838	0.65
72_I	293_W	0.837	0.65
210_R	403_T	0.834	0.64
11_Y	39_E	0.833	0.64
19_T	356_G	0.833	0.64
435_G	459_K	0.833	0.64
48_E	194_Q	0.831	0.64
145_E	296_E	0.831	0.64
189_Y	209_L	0.831	0.64
464_A	497_T	0.830	0.64
183_D	342_S	0.829	0.64
318_Q	637_L	0.828	0.64
433_P	459_K	0.826	0.64
274_S	419_Y	0.825	0.63
423_L	428_H	0.824	0.63
424_N	600_P	0.824	0.63
187_E	206_H	0.822	0.63
244_G	259_L	0.822	0.63
218_M	222_A	0.822	0.63
467_G	561_G	0.820	0.63
486_H	493_E	0.819	0.63
65_Y	68_G	0.819	0.63
583_V	586_Y	0.817	0.63
443_L	587_A	0.816	0.63
176_L	195_V	0.816	0.63
297_T	320_E	0.816	0.63
393_Y	398_K	0.815	0.63
182_T	189_Y	0.815	0.63
30_V	362_Y	0.814	0.62
11_Y	141_Q	0.813	0.62
45_M	54_V	0.812	0.62
411_H	415_V	0.812	0.62
443_L	592_I	0.811	0.62
35_V	69_I	0.810	0.62
464_A	559_G	0.809	0.62
110_C	157_T	0.809	0.62
278_L	415_V	0.808	0.62
88_R	115_Y	0.807	0.62
366_L	370_R	0.807	0.62
44_V	56_F	0.807	0.62
284_R	430_D	0.806	0.62
455_E	458_K	0.805	0.62
36_R	141_Q	0.805	0.62
544_A	548_A	0.801	0.61
257_Q	435_G	0.800	0.61
38_G	41_A	0.800	0.61
595_R	604_V	0.799	0.61
442_R	463_F	0.796	0.61
207_A	343_G	0.794	0.61
165_W	170_Y	0.792	0.60
261_F	331_G	0.791	0.60
268_A	297_T	0.790	0.60
297_T	335_W	0.788	0.60
458_K	461_S	0.787	0.60
632_S	641_L	0.787	0.60
634_T	638_T	0.787	0.60
13_E	183_D	0.786	0.60
116_F	143_D	0.786	0.60
40_F	78_P	0.786	0.60
320_E	620_M	0.784	0.60
112_N	158_C	0.784	0.60
506_F	547_G	0.780	0.59
9_C	14_L	0.780	0.59
329_S	332_F	0.779	0.59
225_A	229_A	0.778	0.59
277_L	605_A	0.778	0.59
492_G	495_E	0.777	0.59
36_R	74_C	0.774	0.59
457_I	497_T	0.774	0.59
442_R	466_A	0.774	0.59
380_L	383_E	0.774	0.59
141_Q	228_Q	0.771	0.58
170_Y	212_M	0.770	0.58
37_I	60_I	0.770	0.58
316_Y	319_A	0.770	0.58
236_S	239_P	0.769	0.58
184_V	335_W	0.768	0.58
78_P	109_A	0.767	0.58
125_T	231_I	0.766	0.58
437_P	440_G	0.765	0.58
360_I	364_N	0.763	0.57
341_R	487_T	0.762	0.57
317_L	334_Y	0.755	0.57
302_A	348_H	0.753	0.56
566_L	570_P	0.751	0.56
111_T	221_I	0.751	0.56
102_G	199_G	0.750	0.56
62_A	136_G	0.749	0.56
21_Q	67_S	0.749	0.56
347_S	478_G	0.749	0.56
554_T	563_I	0.746	0.56
570_P	582_L	0.745	0.56
121_A	230_K	0.744	0.56
406_H	409_L	0.743	0.55
313_A	545_G	0.742	0.55
418_F	566_L	0.740	0.55
454_S	493_E	0.740	0.55
49_E	122_I	0.739	0.55
275_A	416_T	0.738	0.55
578_M	582_L	0.735	0.55
76_P	143_D	0.735	0.55
4_L	194_Q	0.734	0.55
450_P	479_R	0.731	0.54
269_S	305_L	0.729	0.54
7_G	10_Y	0.728	0.54
515_G	543_E	0.728	0.54
14_L	336_L	0.726	0.54
533_T	536_G	0.725	0.54
164_D	168_N	0.722	0.53
277_L	281_D	0.722	0.53
48_E	190_Q	0.722	0.53
531_F	542_V	0.721	0.53
91_R	277_L	0.721	0.53
564_V	582_L	0.720	0.53
90_E	157_T	0.720	0.53
29_E	358_P	0.720	0.53
553_L	586_Y	0.720	0.53
390_A	441_Y	0.716	0.53
129_K	133_R	0.715	0.53
143_D	224_F	0.714	0.52
9_C	335_W	0.714	0.52
422_I	583_V	0.714	0.52
171_G	175_R	0.712	0.52
82_I	190_Q	0.711	0.52
183_D	188_T	0.711	0.52
262_A	286_L	0.710	0.52
111_T	220_M	0.709	0.52
416_T	419_Y	0.708	0.52
377_P	614_V	0.708	0.52
472_T	476_T	0.708	0.52
93_H	151_A	0.708	0.52
28_R	68_G	0.705	0.52
107_Q	151_A	0.705	0.52
49_E	119_K	0.704	0.51
33_N	369_E	0.700	0.51
167_K	173_I	0.700	0.51
564_V	586_Y	0.700	0.51
91_R	113_N	0.698	0.51
102_G	197_Q	0.696	0.51
298_S	320_E	0.693	0.50
58_K	62_A	0.692	0.50
530_V	547_G	0.692	0.50
11_Y	74_C	0.692	0.50
49_E	52_I	0.691	0.50
318_Q	654_Y	0.690	0.50
507_P	527_W	0.690	0.50
65_Y	70_E	0.690	0.50
633_G	655_R	0.689	0.50
93_H	100_I	0.689	0.50
298_S	305_L	0.687	0.50
157_T	160_R	0.686	0.50
30_V	369_E	0.686	0.50
181_G	352_L	0.686	0.50
299_P	349_G	0.685	0.50
404_E	475_L	0.685	0.50
392_T	429_R	0.685	0.50
303_A	308_S	0.685	0.50
232_I	240_I	0.684	0.49
230_K	234_C	0.684	0.49
598_V	604_V	0.683	0.49
171_G	557_N	0.682	0.49
158_C	213_Y	0.682	0.49
214_Q	402_K	0.682	0.49
158_C	220_M	0.682	0.49
167_K	171_G	0.681	0.49
161_L	164_D	0.680	0.49
220_M	223_S	0.677	0.49
142_L	225_A	0.675	0.49
93_H	109_A	0.675	0.49
334_Y	368_V	0.675	0.49
38_G	127_I	0.674	0.48
425_T	583_V	0.674	0.48
502_T	529_A	0.673	0.48
318_Q	653_E	0.673	0.48
18_E	592_I	0.672	0.48
164_D	193_E	0.672	0.48
339_Q	353_S	0.671	0.48
32_V	35_V	0.670	0.48
443_L	471_I	0.670	0.48
16_D	19_T	0.670	0.48
464_A	563_I	0.668	0.48
288_Q	440_G	0.666	0.48
24_I	35_V	0.666	0.48
553_L	582_L	0.665	0.47
107_Q	116_F	0.664	0.47
226_D	229_A	0.663	0.47
541_T	597_D	0.662	0.47
139_G	238_A	0.662	0.47
253_E	285_N	0.661	0.47
355_W	359_T	0.661	0.47
266_T	319_A	0.660	0.47
20_I	60_I	0.660	0.47
327_L	603_I	0.659	0.47
584_R	597_D	0.658	0.47
80_P	108_H	0.658	0.47
120_A	227_E	0.658	0.47
514_T	528_S	0.658	0.47
87_G	194_Q	0.658	0.47
618_V	654_Y	0.657	0.47
144_N	296_E	0.656	0.47
276_F	279_N	0.656	0.47
425_T	587_A	0.655	0.46
572_G	580_E	0.655	0.46
268_A	324_S	0.655	0.46
322_V	375_I	0.653	0.46
301_Y	391_M	0.653	0.46
545_G	548_A	0.652	0.46
458_K	588_E	0.651	0.46
111_T	255_M	0.651	0.46
394_S	397_A	0.651	0.46
577_A	588_E	0.650	0.46
288_Q	436_A	0.650	0.46
281_D	285_N	0.650	0.46
318_Q	368_V	0.650	0.46
141_Q	312_H	0.648	0.46
438_L	459_K	0.648	0.46
461_S	497_T	0.648	0.46
319_A	620_M	0.648	0.46
300_S	320_E	0.648	0.46
141_Q	336_L	0.648	0.46
499_G	554_T	0.648	0.46
245_S	252_N	0.647	0.46
291_P	405_P	0.647	0.46
514_T	524_L	0.646	0.46
325_Y	372_R	0.645	0.45
316_Y	320_E	0.645	0.45
282_L	395_D	0.645	0.45
60_I	63_R	0.645	0.45
365_V	369_E	0.644	0.45
109_A	151_A	0.644	0.45
121_A	124_T	0.644	0.45
472_T	531_F	0.643	0.45
48_E	191_T	0.643	0.45
61_I	238_A	0.642	0.45
7_G	13_E	0.642	0.45
241_T	261_F	0.641	0.45
243_N	295_L	0.640	0.45
297_T	324_S	0.640	0.45
389_A	445_F	0.640	0.45
225_A	259_L	0.639	0.45
386_Q	389_A	0.639	0.45
244_G	256_F	0.639	0.45
55_G	130_E	0.638	0.45
252_N	264_Y	0.637	0.45
191_T	440_G	0.637	0.45
299_P	303_A	0.637	0.45
497_T	556_R	0.637	0.45
363_Q	503_L	0.636	0.45
85_S	92_M	0.634	0.44
109_A	320_E	0.633	0.44
206_H	344_S	0.631	0.44
540_G	552_F	0.629	0.44
66_D	164_D	0.628	0.44
377_P	636_L	0.627	0.44
124_T	224_F	0.627	0.44
524_L	570_P	0.627	0.44
456_F	460_A	0.626	0.44
41_A	45_M	0.625	0.43
617_V	657_I	0.625	0.43
230_K	240_I	0.623	0.43
449_V	456_F	0.623	0.43
535_S	538_T	0.623	0.43
38_G	45_M	0.622	0.43
587_A	590_A	0.622	0.43
312_H	336_L	0.621	0.43
396_R	604_V	0.620	0.43
487_T	490_G	0.620	0.43
536_G	554_T	0.620	0.43
16_D	20_I	0.620	0.43
6_H	334_Y	0.620	0.43
163_H	193_E	0.619	0.43
330_Q	607_R	0.619	0.43
191_T	195_V	0.619	0.43
389_A	587_A	0.619	0.43
145_E	267_Y	0.619	0.43
190_Q	193_E	0.618	0.43
577_A	640_R	0.618	0.43
615_W	633_G	0.617	0.43
645_G	648_A	0.617	0.43
113_N	157_T	0.616	0.43
265_D	335_W	0.616	0.43
11_Y	14_L	0.616	0.43
396_R	436_A	0.615	0.42
212_M	215_L	0.615	0.42
417_H	569_L	0.614	0.42
78_P	107_Q	0.614	0.42
221_I	250_V	0.614	0.42
417_H	572_G	0.614	0.42
531_F	565_M	0.613	0.42
8_A	39_E	0.613	0.42
338_R	356_G	0.613	0.42
634_T	641_L	0.612	0.42
432_I	444_L	0.612	0.42
346_I	450_P	0.611	0.42
17_E	21_Q	0.609	0.42
159_L	196_P	0.608	0.42
84_F	143_D	0.608	0.42
605_A	620_M	0.608	0.42
172_V	193_E	0.607	0.42
276_F	323_S	0.607	0.42
297_T	321_A	0.606	0.42
440_G	465_E	0.605	0.41
72_I	139_G	0.604	0.41
515_G	544_A	0.604	0.41
34_V	70_E	0.604	0.41
156_E	159_L	0.603	0.41
604_V	615_W	0.602	0.41
304_S	348_H	0.602	0.41
460_A	612_G	0.601	0.41
460_A	502_T	0.601	0.41
398_K	411_H	0.601	0.41
266_T	323_S	0.601	0.41
156_E	199_G	0.599	0.41
589_E	627_V	0.599	0.41
90_E	128_A	0.598	0.41
625_G	628_T	0.598	0.41
187_E	201_A	0.597	0.41
34_V	139_G	0.597	0.41
8_A	34_V	0.597	0.41
134_L	137_L	0.596	0.41
8_A	11_Y	0.596	0.41
196_P	209_L	0.595	0.40
389_A	592_I	0.595	0.40
607_R	616_I	0.595	0.40
585_H	641_L	0.595	0.40
230_K	453_S	0.595	0.40
523_P	571_S	0.594	0.40
105_S	201_A	0.594	0.40
231_I	235_Y	0.593	0.40
386_Q	608_I	0.593	0.40
11_Y	41_A	0.593	0.40
452_L	456_F	0.592	0.40
415_V	431_L	0.592	0.40
73_M	127_I	0.591	0.40
116_F	127_I	0.591	0.40
106_R	185_W	0.590	0.40
293_W	333_C	0.590	0.40
18_E	623_K	0.590	0.40
584_R	646_R	0.589	0.40
205_H	210_R	0.589	0.40
603_I	607_R	0.587	0.40
478_G	490_G	0.587	0.40
191_T	525_G	0.586	0.40
634_T	646_R	0.585	0.39
414_L	418_F	0.585	0.39
233_R	237_D	0.585	0.39
39_E	228_Q	0.584	0.39
11_Y	36_R	0.583	0.39
39_E	143_D	0.582	0.39
382_T	608_I	0.580	0.39
10_Y	23_D	0.580	0.39
336_L	348_H	0.580	0.39
85_S	107_Q	0.580	0.39
631_E	646_R	0.579	0.39
551_A	554_T	0.578	0.39
305_L	310_Y	0.578	0.39
580_E	584_R	0.578	0.39
25_D	137_L	0.578	0.39
597_D	628_T	0.578	0.39
84_F	115_Y	0.577	0.39
434_E	459_K	0.577	0.39
299_P	339_Q	0.576	0.39
587_A	591_V	0.575	0.39
374_E	636_L	0.575	0.39
124_T	146_F	0.575	0.39
225_A	258_N	0.574	0.38
631_E	641_L	0.573	0.38
8_A	139_G	0.573	0.38
105_S	203_F	0.573	0.38
9_C	15_W	0.572	0.38
153_C	250_V	0.572	0.38
116_F	224_F	0.572	0.38
140_W	260_D	0.572	0.38
22_Q	356_G	0.571	0.38
121_A	234_C	0.571	0.38
266_T	324_S	0.571	0.38
66_D	624_G	0.570	0.38
193_E	584_R	0.570	0.38
418_F	445_F	0.570	0.38
181_G	206_H	0.570	0.38
257_Q	624_G	0.569	0.38
472_T	494_L	0.568	0.38
24_I	71_T	0.568	0.38
322_V	654_Y	0.567	0.38
446_T	464_A	0.567	0.38
281_D	429_R	0.567	0.38
303_A	348_H	0.566	0.38
37_I	62_A	0.565	0.38
56_F	73_M	0.563	0.37
646_R	653_E	0.563	0.37
194_Q	214_Q	0.562	0.37
423_L	426_G	0.561	0.37
189_Y	194_Q	0.561	0.37
106_R	345_E	0.560	0.37
43_S	188_T	0.560	0.37
123_I	228_Q	0.560	0.37
107_Q	204_L	0.559	0.37
180_W	209_L	0.559	0.37
64_L	71_T	0.559	0.37
11_Y	143_D	0.559	0.37
40_F	104_G	0.559	0.37
42_W	46_E	0.559	0.37
108_H	187_E	0.559	0.37
233_R	260_D	0.558	0.37
540_G	553_L	0.558	0.37
56_F	211_T	0.558	0.37
36_R	336_L	0.558	0.37
36_R	72_I	0.557	0.37
391_M	610_E	0.557	0.37
350_S	359_T	0.556	0.37
84_F	90_E	0.556	0.37
375_I	378_I	0.556	0.37
197_Q	213_Y	0.556	0.37
283_W	286_L	0.556	0.37
628_T	646_R	0.555	0.37
339_Q	348_H	0.554	0.36
421_R	579_L	0.554	0.36
465_E	537_N	0.553	0.36
64_L	67_S	0.553	0.36
123_I	127_I	0.552	0.36
144_N	243_N	0.551	0.36
201_A	206_H	0.550	0.36
330_Q	380_L	0.550	0.36
446_T	452_L	0.550	0.36
177_N	345_E	0.549	0.36
395_D	398_K	0.549	0.36
230_K	258_N	0.549	0.36
118_K	455_E	0.548	0.36
85_S	91_R	0.548	0.36
591_V	594_S	0.548	0.36
470_W	563_I	0.548	0.36
467_G	559_G	0.548	0.36
428_H	605_A	0.547	0.36
214_Q	249_S	0.547	0.36
393_Y	415_V	0.546	0.36
172_V	432_I	0.546	0.36
519_G	541_T	0.546	0.36
189_Y	195_V	0.545	0.36
581_A	584_R	0.545	0.36
367_A	637_L	0.545	0.36
217_S	220_M	0.544	0.36
32_V	337_W	0.543	0.35
317_L	321_A	0.542	0.35
473_G	592_I	0.542	0.35
414_L	474_P	0.542	0.35
502_T	531_F	0.540	0.35
310_Y	530_V	0.540	0.35
567_G	570_P	0.540	0.35
11_Y	228_Q	0.540	0.35
15_W	338_R	0.539	0.35
146_F	224_F	0.539	0.35
496_K	534_E	0.539	0.35
367_A	650_G	0.538	0.35
363_Q	458_K	0.538	0.35
477_G	492_G	0.538	0.35
14_L	340_Q	0.538	0.35
21_Q	593_S	0.538	0.35
76_P	228_Q	0.537	0.35
229_A	240_I	0.537	0.35
531_F	554_T	0.536	0.35
476_T	491_L	0.536	0.35
374_E	635_D	0.536	0.35
528_S	544_A	0.536	0.35
421_R	425_T	0.535	0.35
120_A	224_F	0.535	0.35
266_T	297_T	0.534	0.35
222_A	259_L	0.534	0.35
101_M	105_S	0.533	0.35
363_Q	367_A	0.533	0.35
580_E	583_V	0.533	0.35
90_E	118_K	0.533	0.35
61_I	132_G	0.532	0.34
322_V	426_G	0.532	0.34
465_E	647_L	0.532	0.34
581_A	648_A	0.532	0.34
107_Q	143_D	0.531	0.34
653_E	657_I	0.531	0.34
517_A	585_H	0.531	0.34
252_N	283_W	0.530	0.34
8_A	74_C	0.529	0.34
300_S	346_I	0.529	0.34
115_Y	157_T	0.528	0.34
41_A	183_D	0.528	0.34
641_L	657_I	0.527	0.34
213_Y	249_S	0.527	0.34
268_A	327_L	0.527	0.34
19_T	22_Q	0.527	0.34
92_M	182_T	0.526	0.34
385_V	426_G	0.526	0.34
518_F	634_T	0.526	0.34
351_V	361_G	0.526	0.34
286_L	421_R	0.526	0.34
80_P	107_Q	0.525	0.34
68_G	557_N	0.525	0.34
491_L	495_E	0.524	0.34
246_V	279_N	0.524	0.34
6_H	317_L	0.523	0.34
33_N	531_F	0.523	0.34
128_A	140_W	0.523	0.34
463_F	466_A	0.522	0.34
637_L	640_R	0.522	0.34
49_E	127_I	0.522	0.34
175_R	577_A	0.522	0.34
223_S	227_E	0.521	0.33
626_S	650_G	0.521	0.33
222_A	225_A	0.519	0.33
28_R	172_V	0.519	0.33
232_I	584_R	0.519	0.33
358_P	362_Y	0.517	0.33
121_A	392_T	0.517	0.33
391_M	415_V	0.517	0.33
319_A	323_S	0.517	0.33
39_E	475_L	0.516	0.33
553_L	564_V	0.516	0.33
548_A	628_T	0.516	0.33
213_Y	334_Y	0.515	0.33
553_L	567_G	0.515	0.33
371_A	374_E	0.515	0.33
435_G	453_S	0.514	0.33
599_T	604_V	0.514	0.33
462_A	517_A	0.514	0.33
305_L	309_A	0.514	0.33
232_I	238_A	0.513	0.33
88_R	91_R	0.513	0.33
385_V	605_A	0.512	0.33
66_D	272_N	0.512	0.33
225_A	255_M	0.512	0.33
40_F	338_R	0.511	0.33
24_I	28_R	0.511	0.33
86_H	103_H	0.511	0.33
541_T	549_G	0.511	0.33
48_E	164_D	0.509	0.32
187_E	343_G	0.509	0.32
316_Y	652_H	0.509	0.32
533_T	556_R	0.508	0.32
250_V	255_M	0.508	0.32
126_A	445_F	0.508	0.32
254_R	435_G	0.508	0.32
370_R	458_K	0.508	0.32
218_M	399_A	0.508	0.32
170_Y	180_W	0.507	0.32
253_E	395_D	0.507	0.32
56_F	76_P	0.507	0.32
248_F	280_C	0.507	0.32
489_C	492_G	0.507	0.32
324_S	329_S	0.506	0.32
562_K	634_T	0.506	0.32
178_E	523_P	0.505	0.32
434_E	456_F	0.504	0.32
319_A	652_H	0.504	0.32
26_I	29_E	0.504	0.32
185_W	345_E	0.504	0.32
414_L	417_H	0.504	0.32
464_A	467_G	0.503	0.32
552_F	568_S	0.503	0.32
109_A	143_D	0.503	0.32
361_G	504_F	0.503	0.32
631_E	638_T	0.502	0.32
448_F	474_P	0.502	0.32
91_R	224_F	0.502	0.32
91_R	143_D	0.501	0.32
319_A	334_Y	0.501	0.32
468_G	561_G	0.501	0.32
327_L	334_Y	0.501	0.32
250_V	395_D	0.500	0.32
496_K	608_I	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4uozA	3	0.9849	100	0.273	Contact Map
3ttyA	4	0.9804	100	0.273	Contact Map
4oifA	3	0.9789	100	0.277	Contact Map
1kwgA	3	0.9367	100	0.292	Contact Map
4d1iA	4	0.6968	100	0.673	Contact Map
3u7vA	3	0.6335	100	0.685	Contact Map
2zuvA	2	0.8627	100	0.699	Contact Map
1wdpA	1	0.5822	100	0.723	Contact Map
1fa2A	3	0.5837	100	0.742	Contact Map
4bq2A	4	0.5023	100	0.749	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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