YESS - BACSU - GREMLIN Contacts

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YESS - HTH-type transcriptional regulator YesS

UniProt:	O31522	Sequences: MKKQPQQKERVSRWKGTYFKRNFVFILLIACIPGLLTGGAIYFLSIDKVEKELQRSHETQVAREVSRMDEKLGVLELALTQMAYDSSLMNGLAERDLEKDFTFSYQLTKKLFLLRDQQPLIEQASIFLNSPRPLVLSPEYSALTEQEALRKYRSLLASDHSIYWKRSGNQAMLIQLIPGAAEKPFGAIMLAVDPKEMESILQSLSPYPDGSALLLDQNREVLFHEGEKDFEKTLLHEIKKQPAENGHFQMEWKGKVYSVSFGEMNRMHQQWTFVSAAPLSAITAPMVFLSKVIIVMLVICIGLAVCMTWYASKKIYRPIQHLLGLFTGGEKKTWQASGQDEFKWIEKRWQDLSLESRKLQQQLLRQTPHMKKSFLQHLLQSDFYYDNEESLRFRMEEAGWNIGGNVFHVLDLQVTGLRCEKSIFREGDEQLAVFTLTNIAEELAAKRVFQLSILDIGRLSVTVLVMKTNSSDLKAYITELARQFGDVTGLCLTSTLSSKTERVTEIPSLFQDVKCGKSRRKFANRDQVIDLQADFPRDEQFAPYYPFELEKQIVQTIRLERKQEAKELIDGCMKELSEKAAIDRHVHSALIQLFSRIQEDILHSGLNPSELFQHRNPFLDISELREPNEAAAWLMDVVVTPYLSKLEGRKNRQQKQLAERVIAMIHEQYMADISLESCADALGMNSYTLSKAFKQVTGINFIDYVTQIRIEKAKELLVNTNKKIHDVSEEVGYRHNYFNRIFKKQVGMPPGVFRQMYQETP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	761 (593)
Sequences:	7341 (6677)
Seq/√Len:	274.2

BACSU - YESS YTDP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
338_G	343_K	4.927	1.00
21_R	340_D	3.790	1.00
328_G	333_T	3.631	1.00
340_D	343_K	3.531	1.00
464_L	467_K	3.252	1.00
39_G	43_F	3.247	1.00
553_I	556_T	3.237	1.00
565_A	569_I	3.219	1.00
436_L	440_A	3.195	1.00
460_S	467_K	3.049	1.00
156_L	184_P	2.878	1.00
326_F	352_L	2.702	1.00
436_L	447_R	2.603	1.00
460_S	464_L	2.534	1.00
372_K	376_Q	2.522	1.00
413_Q	416_G	2.437	1.00
453_I	457_G	2.434	1.00
209_D	281_A	2.432	1.00
390_S	394_R	2.427	1.00
125_S	189_M	2.403	1.00
478_T	482_R	2.383	1.00
161_S	164_W	2.378	1.00
379_L	383_F	2.368	1.00
564_E	567_E	2.363	1.00
562_K	565_A	2.315	1.00
19_F	313_K	2.315	1.00
618_F	622_S	2.297	1.00
312_S	316_Y	2.288	1.00
337_S	350_Q	2.286	1.00
327_T	344_W	2.281	1.00
377_H	381_S	2.263	1.00
393_F	397_E	2.191	1.00
576_L	579_K	2.190	1.00
377_H	383_F	2.186	1.00
17_T	20_K	2.171	1.00
256_V	279_L	2.138	1.00
377_H	382_D	2.126	1.00
337_S	357_R	2.091	1.00
567_E	571_G	2.090	1.00
350_Q	353_S	2.060	1.00
568_L	571_G	2.018	1.00
128_L	132_R	1.988	1.00
562_K	569_I	1.967	1.00
461_V	464_L	1.958	1.00
381_S	384_Y	1.954	1.00
493_T	511_Q	1.951	1.00
515_C	518_S	1.944	1.00
565_A	568_L	1.932	1.00
468_T	471_S	1.922	1.00
569_I	572_C	1.907	1.00
394_R	398_A	1.907	1.00
291_K	295_V	1.905	1.00
617_P	620_D	1.904	1.00
469_N	538_D	1.893	1.00
474_K	536_P	1.882	1.00
295_V	299_I	1.880	1.00
326_F	349_W	1.871	1.00
329_G	353_S	1.866	1.00
435_T	438_N	1.833	1.00
567_E	570_D	1.826	1.00
563_Q	567_E	1.816	1.00
377_H	384_Y	1.808	1.00
453_I	467_K	1.787	1.00
460_S	465_V	1.783	1.00
611_L	618_F	1.780	1.00
599_E	603_H	1.767	1.00
566_K	570_D	1.758	1.00
172_M	191_A	1.758	1.00
213_L	274_V	1.752	1.00
313_K	317_R	1.724	1.00
41_I	293_I	1.723	1.00
438_N	442_E	1.720	1.00
454_L	457_G	1.720	1.00
584_R	588_S	1.709	1.00
550_E	553_I	1.706	1.00
363_L	367_T	1.705	1.00
179_G	183_K	1.703	1.00
457_G	460_S	1.700	1.00
562_K	566_K	1.691	1.00
493_T	514_K	1.691	1.00
505_E	508_S	1.688	1.00
154_S	157_A	1.688	1.00
469_N	534_D	1.687	1.00
263_E	272_T	1.681	1.00
445_A	448_V	1.676	1.00
562_K	568_L	1.673	1.00
520_R	525_R	1.673	1.00
599_E	602_L	1.657	1.00
461_V	467_K	1.656	1.00
479_E	523_A	1.649	1.00
585_H	588_S	1.647	1.00
547_F	551_K	1.631	1.00
322_L	326_F	1.630	1.00
476_Y	531_L	1.627	1.00
610_E	613_Q	1.619	1.00
551_K	554_V	1.618	1.00
611_L	614_H	1.605	1.00
433_V	436_L	1.601	1.00
329_G	352_L	1.601	1.00
199_S	202_Q	1.585	1.00
475_A	478_T	1.584	1.00
393_F	396_E	1.579	1.00
457_G	465_V	1.574	1.00
457_G	461_V	1.573	1.00
559_L	569_I	1.559	1.00
401_N	404_G	1.555	1.00
160_H	163_Y	1.553	1.00
609_S	613_Q	1.546	1.00
390_S	393_F	1.543	1.00
622_S	625_R	1.539	1.00
555_Q	558_R	1.538	1.00
617_P	622_S	1.536	1.00
232_K	236_H	1.528	1.00
391_L	398_A	1.523	1.00
469_N	472_D	1.521	1.00
112_F	116_D	1.509	1.00
178_P	184_P	1.506	1.00
394_R	397_E	1.501	1.00
564_E	568_L	1.501	1.00
357_R	361_Q	1.495	1.00
255_K	278_P	1.492	1.00
153_R	157_A	1.490	1.00
600_D	604_S	1.488	1.00
565_A	572_C	1.484	1.00
453_I	456_I	1.484	1.00
391_L	394_R	1.483	1.00
457_G	467_K	1.479	1.00
549_L	556_T	1.473	1.00
46_I	50_E	1.472	1.00
601_I	608_P	1.467	1.00
326_F	345_I	1.465	1.00
472_D	475_A	1.464	1.00
574_K	577_S	1.460	1.00
400_W	403_G	1.458	1.00
577_S	581_A	1.456	1.00
246_G	261_F	1.451	1.00
308_T	312_S	1.446	1.00
323_L	348_R	1.445	1.00
38_G	42_Y	1.443	1.00
618_F	625_R	1.437	1.00
603_H	606_L	1.430	1.00
468_T	472_D	1.429	1.00
426_E	430_Q	1.417	1.00
407_F	414_V	1.416	1.00
615_R	618_F	1.416	1.00
133_P	136_L	1.415	1.00
431_L	435_T	1.414	1.00
389_E	393_F	1.412	1.00
150_R	154_S	1.409	1.00
148_A	152_Y	1.409	1.00
322_L	346_E	1.395	1.00
323_L	344_W	1.392	1.00
16_G	20_K	1.385	1.00
500_T	503_V	1.384	1.00
575_E	579_K	1.376	1.00
411_D	418_R	1.375	1.00
324_G	327_T	1.370	1.00
562_K	572_C	1.365	1.00
395_M	398_A	1.360	1.00
38_G	297_L	1.352	1.00
596_R	599_E	1.350	1.00
327_T	351_D	1.340	1.00
549_L	553_I	1.338	1.00
554_V	558_R	1.334	1.00
415_T	418_R	1.333	1.00
380_Q	384_Y	1.321	1.00
30_A	304_A	1.320	1.00
457_G	464_L	1.317	1.00
365_R	369_H	1.312	1.00
573_M	579_K	1.310	1.00
596_R	600_D	1.308	1.00
288_F	292_V	1.301	1.00
597_I	601_I	1.301	1.00
35_L	39_G	1.298	1.00
410_L	413_Q	1.296	1.00
43_F	47_D	1.294	1.00
257_Y	276_A	1.293	1.00
559_L	562_K	1.292	1.00
511_Q	514_K	1.292	1.00
440_A	447_R	1.291	1.00
207_Y	281_A	1.287	1.00
168_G	195_K	1.287	1.00
40_A	44_L	1.275	1.00
108_T	112_F	1.274	1.00
456_I	459_L	1.273	1.00
461_V	465_V	1.271	1.00
597_I	604_S	1.270	1.00
212_A	275_S	1.269	1.00
344_W	347_K	1.268	1.00
453_I	461_V	1.266	1.00
458_R	467_K	1.265	1.00
18_Y	342_F	1.264	1.00
34_G	37_T	1.259	1.00
602_L	606_L	1.258	1.00
372_K	375_L	1.256	1.00
69_D	73_G	1.255	1.00
379_L	382_D	1.255	1.00
327_T	331_K	1.252	1.00
249_Q	279_L	1.251	1.00
426_E	429_E	1.248	1.00
160_H	164_W	1.248	1.00
407_F	411_D	1.243	1.00
71_K	75_L	1.237	1.00
578_E	581_A	1.233	1.00
196_E	199_S	1.232	1.00
250_M	257_Y	1.230	1.00
585_H	589_A	1.228	1.00
608_P	611_L	1.227	1.00
566_K	569_I	1.227	1.00
23_F	27_L	1.225	1.00
362_Q	365_R	1.222	1.00
611_L	615_R	1.221	1.00
518_S	522_F	1.218	1.00
390_S	397_E	1.215	1.00
399_G	402_I	1.212	1.00
574_K	578_E	1.212	1.00
416_G	419_C	1.210	1.00
458_R	465_V	1.208	1.00
607_N	611_L	1.206	1.00
438_N	441_E	1.206	1.00
583_D	593_L	1.206	1.00
412_L	416_G	1.205	1.00
481_A	525_R	1.194	1.00
61_V	65_V	1.192	1.00
439_I	442_E	1.191	1.00
279_L	283_T	1.188	1.00
147_E	152_Y	1.186	1.00
552_Q	556_T	1.184	1.00
459_L	462_T	1.181	1.00
145_E	148_A	1.180	1.00
452_S	456_I	1.179	1.00
216_D	220_E	1.178	1.00
436_L	443_L	1.177	1.00
594_F	597_I	1.170	1.00
597_I	611_L	1.165	1.00
440_A	443_L	1.164	1.00
161_S	165_K	1.160	1.00
364_L	368_P	1.160	1.00
454_L	467_K	1.158	1.00
441_E	445_A	1.157	1.00
148_A	151_K	1.157	1.00
590_L	593_L	1.154	1.00
211_S	224_H	1.152	1.00
410_L	415_T	1.151	1.00
391_L	395_M	1.147	1.00
611_L	622_S	1.140	1.00
575_E	578_E	1.138	1.00
343_K	346_E	1.134	1.00
354_L	358_K	1.128	1.00
596_R	611_L	1.123	1.00
594_F	604_S	1.120	1.00
579_K	593_L	1.118	1.00
597_I	614_H	1.118	1.00
327_T	348_R	1.117	1.00
568_L	572_C	1.115	1.00
569_I	579_K	1.109	1.00
410_L	417_L	1.108	1.00
470_S	539_E	1.106	1.00
390_S	395_M	1.106	1.00
79_L	190_L	1.104	1.00
345_I	349_W	1.101	1.00
19_F	23_F	1.100	1.00
326_F	329_G	1.100	1.00
45_S	289_L	1.098	1.00
403_G	406_V	1.094	1.00
454_L	461_V	1.093	1.00
229_D	232_K	1.091	1.00
613_Q	616_N	1.090	1.00
614_H	617_P	1.086	1.00
121_I	190_L	1.083	1.00
476_Y	532_Q	1.076	1.00
566_K	571_G	1.074	1.00
328_G	336_A	1.073	1.00
211_S	276_A	1.066	1.00
614_H	618_F	1.064	1.00
304_A	308_T	1.064	1.00
292_V	295_V	1.064	1.00
618_F	621_I	1.063	1.00
606_L	610_E	1.062	1.00
195_K	199_S	1.062	1.00
416_G	420_E	1.062	1.00
43_F	46_I	1.058	1.00
125_S	191_A	1.058	1.00
302_G	306_C	1.056	1.00
550_E	554_V	1.055	1.00
551_K	555_Q	1.054	1.00
346_E	350_Q	1.053	1.00
21_R	314_K	1.052	1.00
535_F	539_E	1.052	1.00
287_V	290_S	1.049	1.00
522_F	527_Q	1.047	1.00
453_I	464_L	1.047	1.00
411_D	414_V	1.047	1.00
561_R	568_L	1.045	1.00
73_G	76_E	1.044	1.00
529_I	533_A	1.044	1.00
584_R	587_H	1.040	1.00
104_S	108_T	1.038	1.00
294_I	298_V	1.036	1.00
26_I	308_T	1.036	1.00
607_N	610_E	1.032	1.00
379_L	384_Y	1.032	1.00
143_L	149_L	1.030	1.00
481_A	529_I	1.029	1.00
423_I	427_G	1.025	1.00
217_Q	270_Q	1.024	1.00
421_K	426_E	1.020	1.00
458_R	464_L	1.019	1.00
33_P	300_C	1.016	1.00
392_R	396_E	1.015	1.00
519_R	522_F	1.013	1.00
414_V	417_L	1.012	1.00
103_F	106_Q	1.008	1.00
454_L	460_S	1.008	1.00
600_D	611_L	1.007	1.00
514_K	518_S	1.006	1.00
231_E	235_L	1.006	1.00
520_R	531_L	1.005	1.00
337_S	354_L	1.005	1.00
475_A	479_E	1.005	1.00
371_K	375_L	1.005	1.00
562_K	567_E	1.003	1.00
427_G	430_Q	1.002	1.00
349_W	353_S	1.000	1.00
616_N	619_L	0.998	1.00
568_L	579_K	0.997	1.00
287_V	291_K	0.995	1.00
155_L	174_I	0.994	1.00
594_F	611_L	0.993	1.00
502_R	513_V	0.992	1.00
392_R	397_E	0.991	1.00
179_G	185_F	0.986	1.00
399_G	403_G	0.985	1.00
455_D	458_R	0.979	1.00
604_S	611_L	0.978	1.00
561_R	569_I	0.975	1.00
211_S	225_E	0.974	1.00
65_V	264_M	0.972	1.00
206_P	210_G	0.961	1.00
322_L	345_I	0.961	1.00
439_I	443_L	0.960	1.00
581_A	585_H	0.960	1.00
326_F	348_R	0.960	1.00
305_V	309_W	0.960	1.00
422_S	425_R	0.959	1.00
437_T	440_A	0.958	1.00
414_V	421_K	0.958	1.00
611_L	625_R	0.956	1.00
207_Y	210_G	0.954	1.00
136_L	139_E	0.954	1.00
421_K	429_E	0.953	1.00
37_T	41_I	0.951	1.00
359_L	363_L	0.949	1.00
406_V	409_V	0.949	1.00
434_F	438_N	0.948	1.00
407_F	418_R	0.947	1.00
405_N	409_V	0.947	1.00
363_L	366_Q	0.944	1.00
328_G	352_L	0.944	1.00
52_E	56_S	0.943	1.00
358_K	362_Q	0.941	1.00
500_T	509_L	0.940	1.00
378_L	384_Y	0.940	1.00
151_K	191_A	0.939	1.00
565_A	571_G	0.939	1.00
407_F	410_L	0.939	1.00
522_F	526_D	0.938	1.00
105_Y	109_K	0.937	1.00
616_N	620_D	0.937	1.00
519_R	527_Q	0.936	1.00
353_S	357_R	0.936	1.00
458_R	461_V	0.935	1.00
560_E	569_I	0.932	1.00
152_Y	156_L	0.932	1.00
127_F	133_P	0.931	1.00
345_I	352_L	0.929	1.00
560_E	564_E	0.929	1.00
436_L	439_I	0.929	1.00
45_S	49_V	0.928	1.00
69_D	268_H	0.928	1.00
463_V	467_K	0.924	1.00
562_K	590_L	0.923	1.00
455_D	459_L	0.922	1.00
350_Q	354_L	0.921	1.00
208_P	281_A	0.920	1.00
213_L	224_H	0.920	1.00
146_Q	152_Y	0.916	1.00
30_A	33_P	0.916	1.00
64_E	67_R	0.916	1.00
168_G	193_D	0.915	1.00
598_Q	602_L	0.915	1.00
337_S	353_S	0.915	1.00
613_Q	617_P	0.915	1.00
38_G	293_I	0.914	1.00
400_W	404_G	0.914	1.00
619_L	623_E	0.914	1.00
321_H	324_G	0.914	1.00
76_E	80_T	0.913	1.00
620_D	623_E	0.911	1.00
61_V	275_S	0.905	1.00
154_S	158_S	0.903	1.00
290_S	294_I	0.903	1.00
369_H	372_K	0.902	1.00
573_M	576_L	0.901	1.00
417_L	421_K	0.900	1.00
462_T	465_V	0.898	1.00
263_E	267_M	0.898	1.00
542_A	546_P	0.897	1.00
597_I	600_D	0.896	1.00
66_S	69_D	0.893	1.00
573_M	577_S	0.891	1.00
159_D	178_P	0.891	1.00
601_I	604_S	0.888	1.00
174_I	187_A	0.887	1.00
74_V	77_L	0.886	1.00
454_L	458_R	0.885	1.00
406_V	410_L	0.884	1.00
322_L	349_W	0.883	1.00
367_T	374_F	0.883	1.00
526_D	529_I	0.881	1.00
50_E	54_Q	0.880	1.00
106_Q	109_K	0.878	1.00
332_K	352_L	0.877	1.00
42_Y	290_S	0.877	1.00
16_G	21_R	0.875	1.00
550_E	556_T	0.874	1.00
597_I	618_F	0.874	1.00
389_E	392_R	0.871	1.00
453_I	460_S	0.870	1.00
607_N	614_H	0.870	1.00
476_Y	520_R	0.870	1.00
127_F	189_M	0.869	1.00
392_R	395_M	0.869	1.00
598_Q	605_G	0.868	1.00
435_T	439_I	0.867	1.00
595_S	599_E	0.866	1.00
599_E	606_L	0.864	1.00
573_M	582_I	0.864	1.00
318_P	322_L	0.861	1.00
596_R	618_F	0.858	1.00
569_I	576_L	0.855	1.00
611_L	617_P	0.854	1.00
145_E	152_Y	0.853	1.00
127_F	146_Q	0.853	1.00
251_E	256_V	0.852	1.00
565_A	579_K	0.852	1.00
291_K	294_I	0.852	1.00
593_L	597_I	0.850	1.00
325_L	349_W	0.848	1.00
388_E	395_M	0.847	1.00
421_K	425_R	0.847	1.00
530_D	534_D	0.841	1.00
126_I	177_I	0.841	1.00
365_R	368_P	0.841	1.00
233_T	236_H	0.839	1.00
537_R	541_F	0.839	1.00
57_H	61_V	0.838	1.00
533_A	537_R	0.837	1.00
429_E	433_V	0.834	1.00
377_H	380_Q	0.833	1.00
579_K	582_I	0.833	1.00
373_S	376_Q	0.832	1.00
545_Y	553_I	0.828	0.99
319_I	345_I	0.824	0.99
540_Q	544_Y	0.823	0.99
363_L	370_M	0.822	0.99
552_Q	555_Q	0.821	0.99
378_L	382_D	0.819	0.99
553_I	557_I	0.818	0.99
16_G	24_V	0.818	0.99
321_H	325_L	0.815	0.99
588_S	592_Q	0.814	0.99
199_S	203_S	0.812	0.99
388_E	392_R	0.812	0.99
539_E	542_A	0.810	0.99
388_E	398_A	0.807	0.99
417_L	422_S	0.806	0.99
378_L	381_S	0.806	0.99
452_S	455_D	0.806	0.99
78_A	81_Q	0.805	0.99
259_V	276_A	0.805	0.99
109_K	112_F	0.804	0.99
409_V	413_Q	0.803	0.99
349_W	352_L	0.803	0.99
606_L	609_S	0.802	0.99
177_I	185_F	0.800	0.99
86_S	89_M	0.800	0.99
111_L	115_R	0.799	0.99
252_W	257_Y	0.796	0.99
473_L	477_I	0.795	0.99
123_Q	191_A	0.794	0.99
454_L	464_L	0.792	0.99
418_R	421_K	0.790	0.99
569_I	573_M	0.790	0.99
312_S	315_I	0.789	0.99
460_S	463_V	0.787	0.99
135_V	138_P	0.786	0.99
544_Y	547_F	0.786	0.99
521_K	526_D	0.784	0.99
333_T	352_L	0.783	0.99
79_L	175_Q	0.782	0.99
152_Y	187_A	0.782	0.99
148_A	156_L	0.782	0.99
159_D	176_L	0.780	0.99
367_T	371_K	0.779	0.99
378_L	383_F	0.777	0.99
338_G	350_Q	0.777	0.99
250_M	259_V	0.775	0.99
573_M	581_A	0.775	0.99
391_L	399_G	0.773	0.99
56_S	59_T	0.773	0.99
423_I	426_E	0.773	0.99
579_K	590_L	0.770	0.99
368_P	372_K	0.768	0.99
499_K	509_L	0.767	0.99
594_F	598_Q	0.767	0.99
370_M	373_S	0.766	0.99
526_D	530_D	0.766	0.99
176_L	184_P	0.765	0.99
65_V	69_D	0.764	0.99
107_L	111_L	0.762	0.99
25_F	304_A	0.762	0.99
127_F	151_K	0.761	0.99
525_R	531_L	0.759	0.99
366_Q	369_H	0.757	0.99
288_F	291_K	0.757	0.99
404_G	407_F	0.757	0.99
114_L	118_Q	0.756	0.99
456_I	460_S	0.755	0.99
589_A	593_L	0.755	0.99
420_E	423_I	0.755	0.99
582_I	587_H	0.755	0.99
18_Y	315_I	0.753	0.99
564_E	569_I	0.753	0.99
572_C	579_K	0.751	0.99
503_V	512_D	0.751	0.99
399_G	404_G	0.750	0.99
213_L	276_A	0.750	0.99
619_L	622_S	0.749	0.99
495_T	516_G	0.749	0.99
582_I	586_V	0.749	0.99
320_Q	323_L	0.747	0.99
608_P	614_H	0.746	0.99
351_D	354_L	0.746	0.99
342_F	346_E	0.746	0.99
364_L	367_T	0.746	0.99
318_P	338_G	0.746	0.99
320_Q	324_G	0.745	0.99
27_L	305_V	0.744	0.99
511_Q	515_C	0.744	0.99
561_R	564_E	0.743	0.99
390_S	398_A	0.743	0.99
513_V	516_G	0.743	0.99
368_P	371_K	0.742	0.99
561_R	565_A	0.741	0.99
486_D	514_K	0.741	0.99
396_E	399_G	0.738	0.99
380_Q	383_F	0.737	0.99
582_I	585_H	0.737	0.99
243_A	246_G	0.736	0.99
151_K	155_L	0.735	0.99
206_P	209_D	0.734	0.99
442_E	445_A	0.734	0.99
339_Q	343_K	0.732	0.99
143_L	147_E	0.732	0.99
237_E	240_K	0.731	0.99
594_F	614_H	0.730	0.99
148_A	153_R	0.730	0.99
476_Y	525_R	0.730	0.99
316_Y	319_I	0.729	0.99
610_E	614_H	0.728	0.99
458_R	462_T	0.726	0.99
566_K	572_C	0.725	0.99
77_L	80_T	0.723	0.99
54_Q	58_E	0.722	0.99
306_C	310_Y	0.722	0.99
193_D	196_E	0.722	0.99
258_S	279_L	0.721	0.99
361_Q	364_L	0.720	0.99
444_A	447_R	0.720	0.99
323_L	327_T	0.718	0.99
476_Y	479_E	0.717	0.99
318_P	342_F	0.715	0.99
413_Q	417_L	0.714	0.98
559_L	568_L	0.714	0.98
560_E	563_Q	0.714	0.98
477_I	481_A	0.713	0.98
500_T	512_D	0.709	0.98
144_T	148_A	0.709	0.98
285_P	288_F	0.709	0.98
537_R	540_Q	0.708	0.98
565_A	570_D	0.707	0.98
439_I	446_K	0.706	0.98
41_I	45_S	0.706	0.98
609_S	612_F	0.706	0.98
418_R	422_S	0.706	0.98
314_K	317_R	0.705	0.98
292_V	296_M	0.705	0.98
395_M	401_N	0.705	0.98
544_Y	548_E	0.703	0.98
559_L	565_A	0.703	0.98
470_S	535_F	0.701	0.98
565_A	582_I	0.700	0.98
259_V	274_V	0.700	0.98
443_L	447_R	0.700	0.98
542_A	549_L	0.699	0.98
477_I	529_I	0.698	0.98
286_M	290_S	0.698	0.98
27_L	30_A	0.698	0.98
613_Q	620_D	0.695	0.98
75_L	78_A	0.693	0.98
574_K	579_K	0.693	0.98
128_L	134_L	0.692	0.98
549_L	552_Q	0.692	0.98
576_L	580_A	0.691	0.98
583_D	586_V	0.691	0.98
603_H	607_N	0.691	0.98
50_E	283_T	0.690	0.98
433_V	447_R	0.687	0.98
19_F	316_Y	0.687	0.98
431_L	434_F	0.687	0.98
582_I	589_A	0.687	0.98
25_F	311_A	0.686	0.98
58_E	62_A	0.685	0.98
422_S	426_E	0.685	0.98
131_P	147_E	0.685	0.98
151_K	187_A	0.683	0.98
477_I	496_L	0.683	0.98
527_Q	530_D	0.682	0.98
170_Q	191_A	0.681	0.98
347_K	350_Q	0.679	0.98
407_F	417_L	0.679	0.98
601_I	611_L	0.679	0.98
65_V	262_G	0.678	0.98
569_I	582_I	0.677	0.98
257_Y	278_P	0.676	0.98
329_G	345_I	0.675	0.98
548_E	551_K	0.674	0.98
160_H	165_K	0.673	0.98
437_T	441_E	0.672	0.98
30_A	308_T	0.671	0.98
487_V	494_S	0.670	0.98
603_H	618_F	0.663	0.98
403_G	407_F	0.663	0.98
563_Q	566_K	0.661	0.98
499_K	503_V	0.660	0.97
579_K	597_I	0.660	0.97
489_G	514_K	0.658	0.97
391_L	400_W	0.658	0.97
296_M	300_C	0.657	0.97
578_E	582_I	0.657	0.97
267_M	270_Q	0.655	0.97
470_S	476_Y	0.655	0.97
329_G	332_K	0.655	0.97
128_L	131_P	0.653	0.97
570_D	574_K	0.653	0.97
477_I	528_V	0.653	0.97
327_T	330_E	0.651	0.97
470_S	474_K	0.651	0.97
135_V	139_E	0.649	0.97
144_T	147_E	0.649	0.97
355_E	359_L	0.648	0.97
413_Q	418_R	0.647	0.97
174_I	189_M	0.647	0.97
216_D	222_L	0.646	0.97
443_L	446_K	0.645	0.97
560_E	565_A	0.644	0.97
15_K	339_Q	0.643	0.97
356_S	360_Q	0.643	0.97
299_I	306_C	0.643	0.97
128_L	133_P	0.641	0.97
421_K	424_F	0.641	0.97
127_F	152_Y	0.641	0.97
596_R	603_H	0.641	0.97
299_I	303_L	0.641	0.97
261_F	274_V	0.640	0.97
404_G	411_D	0.640	0.97
72_L	75_L	0.639	0.97
579_K	586_V	0.637	0.97
255_K	280_S	0.636	0.97
42_Y	46_I	0.635	0.97
596_R	612_F	0.635	0.97
614_H	619_L	0.634	0.97
406_V	415_T	0.634	0.97
55_R	59_T	0.634	0.97
503_V	506_I	0.634	0.97
410_L	418_R	0.633	0.97
452_S	464_L	0.633	0.97
456_I	548_E	0.633	0.97
464_L	542_A	0.633	0.97
442_E	446_K	0.633	0.97
70_E	73_G	0.633	0.97
575_E	582_I	0.630	0.97
559_L	563_Q	0.627	0.97
162_I	165_K	0.627	0.97
315_I	318_P	0.626	0.97
532_Q	536_P	0.624	0.97
471_S	540_Q	0.623	0.96
562_K	571_G	0.620	0.96
143_L	146_Q	0.618	0.96
546_P	553_I	0.616	0.96
421_K	569_I	0.616	0.96
331_K	351_D	0.616	0.96
437_T	446_K	0.615	0.96
481_A	526_D	0.615	0.96
353_S	356_S	0.614	0.96
427_G	431_L	0.613	0.96
31_C	35_L	0.609	0.96
325_L	329_G	0.608	0.96
144_T	152_Y	0.608	0.96
562_K	570_D	0.607	0.96
532_Q	535_F	0.607	0.96
224_H	229_D	0.606	0.96
144_T	149_L	0.606	0.96
608_P	618_F	0.606	0.96
403_G	414_V	0.606	0.96
346_E	349_W	0.605	0.96
289_L	293_I	0.605	0.96
55_R	58_E	0.604	0.96
398_A	402_I	0.604	0.96
243_A	272_T	0.604	0.96
600_D	614_H	0.603	0.96
127_F	149_L	0.602	0.96
611_L	619_L	0.601	0.96
358_K	361_Q	0.601	0.96
369_H	373_S	0.600	0.96
52_E	55_R	0.599	0.96
489_G	493_T	0.599	0.96
64_E	72_L	0.598	0.96
499_K	505_E	0.597	0.96
549_L	557_I	0.597	0.96
561_R	572_C	0.596	0.95
309_W	313_K	0.596	0.95
356_S	359_L	0.595	0.95
22_N	26_I	0.593	0.95
150_R	153_R	0.593	0.95
316_Y	320_Q	0.592	0.95
398_A	401_N	0.592	0.95
322_L	348_R	0.591	0.95
586_V	590_L	0.590	0.95
391_L	397_E	0.589	0.95
59_T	62_A	0.589	0.95
371_K	376_Q	0.589	0.95
314_K	318_P	0.589	0.95
318_P	345_I	0.588	0.95
534_D	538_D	0.588	0.95
329_G	356_S	0.585	0.95
429_E	432_A	0.583	0.95
359_L	362_Q	0.582	0.95
329_G	349_W	0.580	0.95
550_E	557_I	0.580	0.95
415_T	419_C	0.580	0.95
147_E	150_R	0.579	0.95
577_S	580_A	0.579	0.95
184_P	187_A	0.578	0.95
410_L	414_V	0.576	0.95
286_M	289_L	0.576	0.95
579_K	583_D	0.576	0.95
489_G	513_V	0.575	0.95
344_W	348_R	0.575	0.95
27_L	33_P	0.574	0.94
506_I	510_F	0.574	0.94
317_R	321_H	0.573	0.94
425_R	429_E	0.573	0.94
53_L	282_I	0.571	0.94
52_E	285_P	0.570	0.94
440_A	444_A	0.569	0.94
69_D	264_M	0.569	0.94
278_P	281_A	0.568	0.94
496_L	500_T	0.568	0.94
147_E	151_K	0.567	0.94
145_E	149_L	0.566	0.94
600_D	603_H	0.566	0.94
172_M	189_M	0.566	0.94
73_G	77_L	0.565	0.94
352_L	356_S	0.565	0.94
432_A	436_L	0.563	0.94
511_Q	519_R	0.563	0.94
268_H	271_W	0.563	0.94
474_K	478_T	0.561	0.94
146_Q	151_K	0.561	0.94
478_T	481_A	0.560	0.94
325_L	328_G	0.560	0.94
110_K	113_L	0.559	0.94
598_Q	611_L	0.557	0.94
479_E	517_K	0.556	0.93
142_A	145_E	0.555	0.93
506_I	516_G	0.555	0.93
251_E	254_G	0.554	0.93
318_P	343_K	0.554	0.93
596_R	605_G	0.553	0.93
246_G	249_Q	0.552	0.93
410_L	421_K	0.552	0.93
83_A	175_Q	0.552	0.93
105_Y	108_T	0.549	0.93
285_P	289_L	0.549	0.93
17_T	344_W	0.549	0.93
404_G	417_L	0.548	0.93
587_H	591_I	0.547	0.93
275_S	278_P	0.547	0.93
132_R	136_L	0.546	0.93
448_V	455_D	0.546	0.93
213_L	221_V	0.546	0.93
145_E	151_K	0.545	0.93
493_T	518_S	0.545	0.93
618_F	624_L	0.544	0.93
502_R	507_P	0.544	0.93
574_K	581_A	0.543	0.93
586_V	593_L	0.543	0.93
191_A	194_P	0.543	0.93
273_F	278_P	0.542	0.93
414_V	418_R	0.542	0.93
598_Q	618_F	0.541	0.93
491_C	516_G	0.540	0.92
341_E	345_I	0.539	0.92
272_T	275_S	0.539	0.92
436_L	446_K	0.538	0.92
310_Y	313_K	0.537	0.92
447_R	556_T	0.537	0.92
541_F	544_Y	0.537	0.92
342_F	348_R	0.537	0.92
513_V	519_R	0.537	0.92
205_S	208_P	0.536	0.92
22_N	25_F	0.536	0.92
264_M	268_H	0.535	0.92
71_K	74_V	0.534	0.92
313_K	320_Q	0.534	0.92
31_C	301_I	0.533	0.92
410_L	477_I	0.532	0.92
180_A	183_K	0.532	0.92
610_E	618_F	0.531	0.92
261_F	272_T	0.531	0.92
491_C	505_E	0.530	0.92
388_E	391_L	0.529	0.92
459_L	463_V	0.529	0.92
36_L	40_A	0.529	0.92
604_S	608_P	0.529	0.92
472_D	527_Q	0.528	0.92
600_D	607_N	0.528	0.92
497_S	503_V	0.527	0.92
78_A	121_I	0.526	0.91
568_L	581_A	0.526	0.91
352_L	355_E	0.526	0.91
623_E	626_E	0.526	0.91
258_S	283_T	0.525	0.91
200_I	203_S	0.524	0.91
317_R	320_Q	0.524	0.91
141_S	147_E	0.524	0.91
44_L	47_D	0.524	0.91
608_P	615_R	0.523	0.91
454_L	465_V	0.522	0.91
263_E	270_Q	0.521	0.91
172_M	271_W	0.521	0.91
586_V	589_A	0.520	0.91
495_T	513_V	0.520	0.91
144_T	151_K	0.518	0.91
132_R	139_E	0.517	0.91
348_R	352_L	0.516	0.91
79_L	83_A	0.515	0.91
220_E	233_T	0.515	0.91
410_L	494_S	0.514	0.91
75_L	190_L	0.514	0.91
496_L	516_G	0.513	0.90
316_Y	323_L	0.512	0.90
210_G	215_L	0.511	0.90
473_L	525_R	0.511	0.90
57_H	277_A	0.510	0.90
44_L	48_K	0.509	0.90
426_E	432_A	0.509	0.90
152_Y	155_L	0.508	0.90
587_H	590_L	0.508	0.90
602_L	605_G	0.508	0.90
492_L	508_S	0.507	0.90
153_R	156_L	0.507	0.90
605_G	608_P	0.506	0.90
596_R	615_R	0.506	0.90
21_R	338_G	0.505	0.90
334_W	360_Q	0.505	0.90
360_Q	363_L	0.505	0.90
316_Y	345_I	0.505	0.90
588_S	591_I	0.504	0.90
583_D	587_H	0.504	0.90
491_C	495_T	0.503	0.90
394_R	399_G	0.503	0.90
141_S	144_T	0.502	0.90
187_A	191_A	0.502	0.90
206_P	281_A	0.501	0.89
545_Y	556_T	0.500	0.89
158_S	161_S	0.500	0.89
421_K	428_D	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1bl0A	1	0.1419	100	0.809	Contact Map
3oioA	1	0.1459	100	0.811	Contact Map
3oouA	1	0.1367	100	0.811	Contact Map
3mn2A	1	0.138	100	0.812	Contact Map
3gbgA	1	0.3298	100	0.812	Contact Map
3mklA	1	0.1445	100	0.815	Contact Map
3w6vA	1	0.1406	100	0.815	Contact Map
2k9sA	1	0.138	100	0.816	Contact Map
3lsgA	2	0.1327	100	0.819	Contact Map
1d5yA	1	0.1419	100	0.82	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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