GREMLIN Database
YESS - HTH-type transcriptional regulator YesS
UniProt: O31522 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 761 (593)
Sequences: 7341 (6677)
Seq/√Len: 274.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
338_G343_K4.9271.00
21_R340_D3.7901.00
328_G333_T3.6311.00
340_D343_K3.5311.00
464_L467_K3.2521.00
39_G43_F3.2471.00
553_I556_T3.2371.00
565_A569_I3.2191.00
436_L440_A3.1951.00
460_S467_K3.0491.00
156_L184_P2.8781.00
326_F352_L2.7021.00
436_L447_R2.6031.00
460_S464_L2.5341.00
372_K376_Q2.5221.00
413_Q416_G2.4371.00
453_I457_G2.4341.00
209_D281_A2.4321.00
390_S394_R2.4271.00
125_S189_M2.4031.00
478_T482_R2.3831.00
161_S164_W2.3781.00
379_L383_F2.3681.00
564_E567_E2.3631.00
562_K565_A2.3151.00
19_F313_K2.3151.00
618_F622_S2.2971.00
312_S316_Y2.2881.00
337_S350_Q2.2861.00
327_T344_W2.2811.00
377_H381_S2.2631.00
393_F397_E2.1911.00
576_L579_K2.1901.00
377_H383_F2.1861.00
17_T20_K2.1711.00
256_V279_L2.1381.00
377_H382_D2.1261.00
337_S357_R2.0911.00
567_E571_G2.0901.00
350_Q353_S2.0601.00
568_L571_G2.0181.00
128_L132_R1.9881.00
562_K569_I1.9671.00
461_V464_L1.9581.00
381_S384_Y1.9541.00
493_T511_Q1.9511.00
515_C518_S1.9441.00
565_A568_L1.9321.00
468_T471_S1.9221.00
569_I572_C1.9071.00
394_R398_A1.9071.00
291_K295_V1.9051.00
617_P620_D1.9041.00
469_N538_D1.8931.00
474_K536_P1.8821.00
295_V299_I1.8801.00
326_F349_W1.8711.00
329_G353_S1.8661.00
435_T438_N1.8331.00
567_E570_D1.8261.00
563_Q567_E1.8161.00
377_H384_Y1.8081.00
453_I467_K1.7871.00
460_S465_V1.7831.00
611_L618_F1.7801.00
599_E603_H1.7671.00
566_K570_D1.7581.00
172_M191_A1.7581.00
213_L274_V1.7521.00
313_K317_R1.7241.00
41_I293_I1.7231.00
438_N442_E1.7201.00
454_L457_G1.7201.00
584_R588_S1.7091.00
550_E553_I1.7061.00
363_L367_T1.7051.00
179_G183_K1.7031.00
457_G460_S1.7001.00
562_K566_K1.6911.00
493_T514_K1.6911.00
505_E508_S1.6881.00
154_S157_A1.6881.00
469_N534_D1.6871.00
263_E272_T1.6811.00
445_A448_V1.6761.00
562_K568_L1.6731.00
520_R525_R1.6731.00
599_E602_L1.6571.00
461_V467_K1.6561.00
479_E523_A1.6491.00
585_H588_S1.6471.00
547_F551_K1.6311.00
322_L326_F1.6301.00
476_Y531_L1.6271.00
610_E613_Q1.6191.00
551_K554_V1.6181.00
611_L614_H1.6051.00
433_V436_L1.6011.00
329_G352_L1.6011.00
199_S202_Q1.5851.00
475_A478_T1.5841.00
393_F396_E1.5791.00
457_G465_V1.5741.00
457_G461_V1.5731.00
559_L569_I1.5591.00
401_N404_G1.5551.00
160_H163_Y1.5531.00
609_S613_Q1.5461.00
390_S393_F1.5431.00
622_S625_R1.5391.00
555_Q558_R1.5381.00
617_P622_S1.5361.00
232_K236_H1.5281.00
391_L398_A1.5231.00
469_N472_D1.5211.00
112_F116_D1.5091.00
178_P184_P1.5061.00
394_R397_E1.5011.00
564_E568_L1.5011.00
357_R361_Q1.4951.00
255_K278_P1.4921.00
153_R157_A1.4901.00
600_D604_S1.4881.00
565_A572_C1.4841.00
453_I456_I1.4841.00
391_L394_R1.4831.00
457_G467_K1.4791.00
549_L556_T1.4731.00
46_I50_E1.4721.00
601_I608_P1.4671.00
326_F345_I1.4651.00
472_D475_A1.4641.00
574_K577_S1.4601.00
400_W403_G1.4581.00
577_S581_A1.4561.00
246_G261_F1.4511.00
308_T312_S1.4461.00
323_L348_R1.4451.00
38_G42_Y1.4431.00
618_F625_R1.4371.00
603_H606_L1.4301.00
468_T472_D1.4291.00
426_E430_Q1.4171.00
407_F414_V1.4161.00
615_R618_F1.4161.00
133_P136_L1.4151.00
431_L435_T1.4141.00
389_E393_F1.4121.00
150_R154_S1.4091.00
148_A152_Y1.4091.00
322_L346_E1.3951.00
323_L344_W1.3921.00
16_G20_K1.3851.00
500_T503_V1.3841.00
575_E579_K1.3761.00
411_D418_R1.3751.00
324_G327_T1.3701.00
562_K572_C1.3651.00
395_M398_A1.3601.00
38_G297_L1.3521.00
596_R599_E1.3501.00
327_T351_D1.3401.00
549_L553_I1.3381.00
554_V558_R1.3341.00
415_T418_R1.3331.00
380_Q384_Y1.3211.00
30_A304_A1.3201.00
457_G464_L1.3171.00
365_R369_H1.3121.00
573_M579_K1.3101.00
596_R600_D1.3081.00
288_F292_V1.3011.00
597_I601_I1.3011.00
35_L39_G1.2981.00
410_L413_Q1.2961.00
43_F47_D1.2941.00
257_Y276_A1.2931.00
559_L562_K1.2921.00
511_Q514_K1.2921.00
440_A447_R1.2911.00
207_Y281_A1.2871.00
168_G195_K1.2871.00
40_A44_L1.2751.00
108_T112_F1.2741.00
456_I459_L1.2731.00
461_V465_V1.2711.00
597_I604_S1.2701.00
212_A275_S1.2691.00
344_W347_K1.2681.00
453_I461_V1.2661.00
458_R467_K1.2651.00
18_Y342_F1.2641.00
34_G37_T1.2591.00
602_L606_L1.2581.00
372_K375_L1.2561.00
69_D73_G1.2551.00
379_L382_D1.2551.00
327_T331_K1.2521.00
249_Q279_L1.2511.00
426_E429_E1.2481.00
160_H164_W1.2481.00
407_F411_D1.2431.00
71_K75_L1.2371.00
578_E581_A1.2331.00
196_E199_S1.2321.00
250_M257_Y1.2301.00
585_H589_A1.2281.00
608_P611_L1.2271.00
566_K569_I1.2271.00
23_F27_L1.2251.00
362_Q365_R1.2221.00
611_L615_R1.2211.00
518_S522_F1.2181.00
390_S397_E1.2151.00
399_G402_I1.2121.00
574_K578_E1.2121.00
416_G419_C1.2101.00
458_R465_V1.2081.00
607_N611_L1.2061.00
438_N441_E1.2061.00
583_D593_L1.2061.00
412_L416_G1.2051.00
481_A525_R1.1941.00
61_V65_V1.1921.00
439_I442_E1.1911.00
279_L283_T1.1881.00
147_E152_Y1.1861.00
552_Q556_T1.1841.00
459_L462_T1.1811.00
145_E148_A1.1801.00
452_S456_I1.1791.00
216_D220_E1.1781.00
436_L443_L1.1771.00
594_F597_I1.1701.00
597_I611_L1.1651.00
440_A443_L1.1641.00
161_S165_K1.1601.00
364_L368_P1.1601.00
454_L467_K1.1581.00
441_E445_A1.1571.00
148_A151_K1.1571.00
590_L593_L1.1541.00
211_S224_H1.1521.00
410_L415_T1.1511.00
391_L395_M1.1471.00
611_L622_S1.1401.00
575_E578_E1.1381.00
343_K346_E1.1341.00
354_L358_K1.1281.00
596_R611_L1.1231.00
594_F604_S1.1201.00
579_K593_L1.1181.00
597_I614_H1.1181.00
327_T348_R1.1171.00
568_L572_C1.1151.00
569_I579_K1.1091.00
410_L417_L1.1081.00
470_S539_E1.1061.00
390_S395_M1.1061.00
79_L190_L1.1041.00
345_I349_W1.1011.00
19_F23_F1.1001.00
326_F329_G1.1001.00
45_S289_L1.0981.00
403_G406_V1.0941.00
454_L461_V1.0931.00
229_D232_K1.0911.00
613_Q616_N1.0901.00
614_H617_P1.0861.00
121_I190_L1.0831.00
476_Y532_Q1.0761.00
566_K571_G1.0741.00
328_G336_A1.0731.00
211_S276_A1.0661.00
614_H618_F1.0641.00
304_A308_T1.0641.00
292_V295_V1.0641.00
618_F621_I1.0631.00
606_L610_E1.0621.00
195_K199_S1.0621.00
416_G420_E1.0621.00
43_F46_I1.0581.00
125_S191_A1.0581.00
302_G306_C1.0561.00
550_E554_V1.0551.00
551_K555_Q1.0541.00
346_E350_Q1.0531.00
21_R314_K1.0521.00
535_F539_E1.0521.00
287_V290_S1.0491.00
522_F527_Q1.0471.00
453_I464_L1.0471.00
411_D414_V1.0471.00
561_R568_L1.0451.00
73_G76_E1.0441.00
529_I533_A1.0441.00
584_R587_H1.0401.00
104_S108_T1.0381.00
294_I298_V1.0361.00
26_I308_T1.0361.00
607_N610_E1.0321.00
379_L384_Y1.0321.00
143_L149_L1.0301.00
481_A529_I1.0291.00
423_I427_G1.0251.00
217_Q270_Q1.0241.00
421_K426_E1.0201.00
458_R464_L1.0191.00
33_P300_C1.0161.00
392_R396_E1.0151.00
519_R522_F1.0131.00
414_V417_L1.0121.00
103_F106_Q1.0081.00
454_L460_S1.0081.00
600_D611_L1.0071.00
514_K518_S1.0061.00
231_E235_L1.0061.00
520_R531_L1.0051.00
337_S354_L1.0051.00
475_A479_E1.0051.00
371_K375_L1.0051.00
562_K567_E1.0031.00
427_G430_Q1.0021.00
349_W353_S1.0001.00
616_N619_L0.9981.00
568_L579_K0.9971.00
287_V291_K0.9951.00
155_L174_I0.9941.00
594_F611_L0.9931.00
502_R513_V0.9921.00
392_R397_E0.9911.00
179_G185_F0.9861.00
399_G403_G0.9851.00
455_D458_R0.9791.00
604_S611_L0.9781.00
561_R569_I0.9751.00
211_S225_E0.9741.00
65_V264_M0.9721.00
206_P210_G0.9611.00
322_L345_I0.9611.00
439_I443_L0.9601.00
581_A585_H0.9601.00
326_F348_R0.9601.00
305_V309_W0.9601.00
422_S425_R0.9591.00
437_T440_A0.9581.00
414_V421_K0.9581.00
611_L625_R0.9561.00
207_Y210_G0.9541.00
136_L139_E0.9541.00
421_K429_E0.9531.00
37_T41_I0.9511.00
359_L363_L0.9491.00
406_V409_V0.9491.00
434_F438_N0.9481.00
407_F418_R0.9471.00
405_N409_V0.9471.00
363_L366_Q0.9441.00
328_G352_L0.9441.00
52_E56_S0.9431.00
358_K362_Q0.9411.00
500_T509_L0.9401.00
378_L384_Y0.9401.00
151_K191_A0.9391.00
565_A571_G0.9391.00
407_F410_L0.9391.00
522_F526_D0.9381.00
105_Y109_K0.9371.00
616_N620_D0.9371.00
519_R527_Q0.9361.00
353_S357_R0.9361.00
458_R461_V0.9351.00
560_E569_I0.9321.00
152_Y156_L0.9321.00
127_F133_P0.9311.00
345_I352_L0.9291.00
560_E564_E0.9291.00
436_L439_I0.9291.00
45_S49_V0.9281.00
69_D268_H0.9281.00
463_V467_K0.9241.00
562_K590_L0.9231.00
455_D459_L0.9221.00
350_Q354_L0.9211.00
208_P281_A0.9201.00
213_L224_H0.9201.00
146_Q152_Y0.9161.00
30_A33_P0.9161.00
64_E67_R0.9161.00
168_G193_D0.9151.00
598_Q602_L0.9151.00
337_S353_S0.9151.00
613_Q617_P0.9151.00
38_G293_I0.9141.00
400_W404_G0.9141.00
619_L623_E0.9141.00
321_H324_G0.9141.00
76_E80_T0.9131.00
620_D623_E0.9111.00
61_V275_S0.9051.00
154_S158_S0.9031.00
290_S294_I0.9031.00
369_H372_K0.9021.00
573_M576_L0.9011.00
417_L421_K0.9001.00
462_T465_V0.8981.00
263_E267_M0.8981.00
542_A546_P0.8971.00
597_I600_D0.8961.00
66_S69_D0.8931.00
573_M577_S0.8911.00
159_D178_P0.8911.00
601_I604_S0.8881.00
174_I187_A0.8871.00
74_V77_L0.8861.00
454_L458_R0.8851.00
406_V410_L0.8841.00
322_L349_W0.8831.00
367_T374_F0.8831.00
526_D529_I0.8811.00
50_E54_Q0.8801.00
106_Q109_K0.8781.00
332_K352_L0.8771.00
42_Y290_S0.8771.00
16_G21_R0.8751.00
550_E556_T0.8741.00
597_I618_F0.8741.00
389_E392_R0.8711.00
453_I460_S0.8701.00
607_N614_H0.8701.00
476_Y520_R0.8701.00
127_F189_M0.8691.00
392_R395_M0.8691.00
598_Q605_G0.8681.00
435_T439_I0.8671.00
595_S599_E0.8661.00
599_E606_L0.8641.00
573_M582_I0.8641.00
318_P322_L0.8611.00
596_R618_F0.8581.00
569_I576_L0.8551.00
611_L617_P0.8541.00
145_E152_Y0.8531.00
127_F146_Q0.8531.00
251_E256_V0.8521.00
565_A579_K0.8521.00
291_K294_I0.8521.00
593_L597_I0.8501.00
325_L349_W0.8481.00
388_E395_M0.8471.00
421_K425_R0.8471.00
530_D534_D0.8411.00
126_I177_I0.8411.00
365_R368_P0.8411.00
233_T236_H0.8391.00
537_R541_F0.8391.00
57_H61_V0.8381.00
533_A537_R0.8371.00
429_E433_V0.8341.00
377_H380_Q0.8331.00
579_K582_I0.8331.00
373_S376_Q0.8321.00
545_Y553_I0.8280.99
319_I345_I0.8240.99
540_Q544_Y0.8230.99
363_L370_M0.8220.99
552_Q555_Q0.8210.99
378_L382_D0.8190.99
553_I557_I0.8180.99
16_G24_V0.8180.99
321_H325_L0.8150.99
588_S592_Q0.8140.99
199_S203_S0.8120.99
388_E392_R0.8120.99
539_E542_A0.8100.99
388_E398_A0.8070.99
417_L422_S0.8060.99
378_L381_S0.8060.99
452_S455_D0.8060.99
78_A81_Q0.8050.99
259_V276_A0.8050.99
109_K112_F0.8040.99
409_V413_Q0.8030.99
349_W352_L0.8030.99
606_L609_S0.8020.99
177_I185_F0.8000.99
86_S89_M0.8000.99
111_L115_R0.7990.99
252_W257_Y0.7960.99
473_L477_I0.7950.99
123_Q191_A0.7940.99
454_L464_L0.7920.99
418_R421_K0.7900.99
569_I573_M0.7900.99
312_S315_I0.7890.99
460_S463_V0.7870.99
135_V138_P0.7860.99
544_Y547_F0.7860.99
521_K526_D0.7840.99
333_T352_L0.7830.99
79_L175_Q0.7820.99
152_Y187_A0.7820.99
148_A156_L0.7820.99
159_D176_L0.7800.99
367_T371_K0.7790.99
378_L383_F0.7770.99
338_G350_Q0.7770.99
250_M259_V0.7750.99
573_M581_A0.7750.99
391_L399_G0.7730.99
56_S59_T0.7730.99
423_I426_E0.7730.99
579_K590_L0.7700.99
368_P372_K0.7680.99
499_K509_L0.7670.99
594_F598_Q0.7670.99
370_M373_S0.7660.99
526_D530_D0.7660.99
176_L184_P0.7650.99
65_V69_D0.7640.99
107_L111_L0.7620.99
25_F304_A0.7620.99
127_F151_K0.7610.99
525_R531_L0.7590.99
366_Q369_H0.7570.99
288_F291_K0.7570.99
404_G407_F0.7570.99
114_L118_Q0.7560.99
456_I460_S0.7550.99
589_A593_L0.7550.99
420_E423_I0.7550.99
582_I587_H0.7550.99
18_Y315_I0.7530.99
564_E569_I0.7530.99
572_C579_K0.7510.99
503_V512_D0.7510.99
399_G404_G0.7500.99
213_L276_A0.7500.99
619_L622_S0.7490.99
495_T516_G0.7490.99
582_I586_V0.7490.99
320_Q323_L0.7470.99
608_P614_H0.7460.99
351_D354_L0.7460.99
342_F346_E0.7460.99
364_L367_T0.7460.99
318_P338_G0.7460.99
320_Q324_G0.7450.99
27_L305_V0.7440.99
511_Q515_C0.7440.99
561_R564_E0.7430.99
390_S398_A0.7430.99
513_V516_G0.7430.99
368_P371_K0.7420.99
561_R565_A0.7410.99
486_D514_K0.7410.99
396_E399_G0.7380.99
380_Q383_F0.7370.99
582_I585_H0.7370.99
243_A246_G0.7360.99
151_K155_L0.7350.99
206_P209_D0.7340.99
442_E445_A0.7340.99
339_Q343_K0.7320.99
143_L147_E0.7320.99
237_E240_K0.7310.99
594_F614_H0.7300.99
148_A153_R0.7300.99
476_Y525_R0.7300.99
316_Y319_I0.7290.99
610_E614_H0.7280.99
458_R462_T0.7260.99
566_K572_C0.7250.99
77_L80_T0.7230.99
54_Q58_E0.7220.99
306_C310_Y0.7220.99
193_D196_E0.7220.99
258_S279_L0.7210.99
361_Q364_L0.7200.99
444_A447_R0.7200.99
323_L327_T0.7180.99
476_Y479_E0.7170.99
318_P342_F0.7150.99
413_Q417_L0.7140.98
559_L568_L0.7140.98
560_E563_Q0.7140.98
477_I481_A0.7130.98
500_T512_D0.7090.98
144_T148_A0.7090.98
285_P288_F0.7090.98
537_R540_Q0.7080.98
565_A570_D0.7070.98
439_I446_K0.7060.98
41_I45_S0.7060.98
609_S612_F0.7060.98
418_R422_S0.7060.98
314_K317_R0.7050.98
292_V296_M0.7050.98
395_M401_N0.7050.98
544_Y548_E0.7030.98
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470_S535_F0.7010.98
565_A582_I0.7000.98
259_V274_V0.7000.98
443_L447_R0.7000.98
542_A549_L0.6990.98
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286_M290_S0.6980.98
27_L30_A0.6980.98
613_Q620_D0.6950.98
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574_K579_K0.6930.98
128_L134_L0.6920.98
549_L552_Q0.6920.98
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603_H607_N0.6910.98
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431_L434_F0.6870.98
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25_F311_A0.6860.98
58_E62_A0.6850.98
422_S426_E0.6850.98
131_P147_E0.6850.98
151_K187_A0.6830.98
477_I496_L0.6830.98
527_Q530_D0.6820.98
170_Q191_A0.6810.98
347_K350_Q0.6790.98
407_F417_L0.6790.98
601_I611_L0.6790.98
65_V262_G0.6780.98
569_I582_I0.6770.98
257_Y278_P0.6760.98
329_G345_I0.6750.98
548_E551_K0.6740.98
160_H165_K0.6730.98
437_T441_E0.6720.98
30_A308_T0.6710.98
487_V494_S0.6700.98
603_H618_F0.6630.98
403_G407_F0.6630.98
563_Q566_K0.6610.98
499_K503_V0.6600.97
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391_L400_W0.6580.97
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72_L75_L0.6390.97
579_K586_V0.6370.97
255_K280_S0.6360.97
42_Y46_I0.6350.97
596_R612_F0.6350.97
614_H619_L0.6340.97
406_V415_T0.6340.97
55_R59_T0.6340.97
503_V506_I0.6340.97
410_L418_R0.6330.97
452_S464_L0.6330.97
456_I548_E0.6330.97
464_L542_A0.6330.97
442_E446_K0.6330.97
70_E73_G0.6330.97
575_E582_I0.6300.97
559_L563_Q0.6270.97
162_I165_K0.6270.97
315_I318_P0.6260.97
532_Q536_P0.6240.97
471_S540_Q0.6230.96
562_K571_G0.6200.96
143_L146_Q0.6180.96
546_P553_I0.6160.96
421_K569_I0.6160.96
331_K351_D0.6160.96
437_T446_K0.6150.96
481_A526_D0.6150.96
353_S356_S0.6140.96
427_G431_L0.6130.96
31_C35_L0.6090.96
325_L329_G0.6080.96
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562_K570_D0.6070.96
532_Q535_F0.6070.96
224_H229_D0.6060.96
144_T149_L0.6060.96
608_P618_F0.6060.96
403_G414_V0.6060.96
346_E349_W0.6050.96
289_L293_I0.6050.96
55_R58_E0.6040.96
398_A402_I0.6040.96
243_A272_T0.6040.96
600_D614_H0.6030.96
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611_L619_L0.6010.96
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561_R572_C0.5960.95
309_W313_K0.5960.95
356_S359_L0.5950.95
22_N26_I0.5930.95
150_R153_R0.5930.95
316_Y320_Q0.5920.95
398_A401_N0.5920.95
322_L348_R0.5910.95
586_V590_L0.5900.95
391_L397_E0.5890.95
59_T62_A0.5890.95
371_K376_Q0.5890.95
314_K318_P0.5890.95
318_P345_I0.5880.95
534_D538_D0.5880.95
329_G356_S0.5850.95
429_E432_A0.5830.95
359_L362_Q0.5820.95
329_G349_W0.5800.95
550_E557_I0.5800.95
415_T419_C0.5800.95
147_E150_R0.5790.95
577_S580_A0.5790.95
184_P187_A0.5780.95
410_L414_V0.5760.95
286_M289_L0.5760.95
579_K583_D0.5760.95
489_G513_V0.5750.95
344_W348_R0.5750.95
27_L33_P0.5740.94
506_I510_F0.5740.94
317_R321_H0.5730.94
425_R429_E0.5730.94
53_L282_I0.5710.94
52_E285_P0.5700.94
440_A444_A0.5690.94
69_D264_M0.5690.94
278_P281_A0.5680.94
496_L500_T0.5680.94
147_E151_K0.5670.94
145_E149_L0.5660.94
600_D603_H0.5660.94
172_M189_M0.5660.94
73_G77_L0.5650.94
352_L356_S0.5650.94
432_A436_L0.5630.94
511_Q519_R0.5630.94
268_H271_W0.5630.94
474_K478_T0.5610.94
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325_L328_G0.5600.94
110_K113_L0.5590.94
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142_A145_E0.5550.93
506_I516_G0.5550.93
251_E254_G0.5540.93
318_P343_K0.5540.93
596_R605_G0.5530.93
246_G249_Q0.5520.93
410_L421_K0.5520.93
83_A175_Q0.5520.93
105_Y108_T0.5490.93
285_P289_L0.5490.93
17_T344_W0.5490.93
404_G417_L0.5480.93
587_H591_I0.5470.93
275_S278_P0.5470.93
132_R136_L0.5460.93
448_V455_D0.5460.93
213_L221_V0.5460.93
145_E151_K0.5450.93
493_T518_S0.5450.93
618_F624_L0.5440.93
502_R507_P0.5440.93
574_K581_A0.5430.93
586_V593_L0.5430.93
191_A194_P0.5430.93
273_F278_P0.5420.93
414_V418_R0.5420.93
598_Q618_F0.5410.93
491_C516_G0.5400.92
341_E345_I0.5390.92
272_T275_S0.5390.92
436_L446_K0.5380.92
310_Y313_K0.5370.92
447_R556_T0.5370.92
541_F544_Y0.5370.92
342_F348_R0.5370.92
513_V519_R0.5370.92
205_S208_P0.5360.92
22_N25_F0.5360.92
264_M268_H0.5350.92
71_K74_V0.5340.92
313_K320_Q0.5340.92
31_C301_I0.5330.92
410_L477_I0.5320.92
180_A183_K0.5320.92
610_E618_F0.5310.92
261_F272_T0.5310.92
491_C505_E0.5300.92
388_E391_L0.5290.92
459_L463_V0.5290.92
36_L40_A0.5290.92
604_S608_P0.5290.92
472_D527_Q0.5280.92
600_D607_N0.5280.92
497_S503_V0.5270.92
78_A121_I0.5260.91
568_L581_A0.5260.91
352_L355_E0.5260.91
623_E626_E0.5260.91
258_S283_T0.5250.91
200_I203_S0.5240.91
317_R320_Q0.5240.91
141_S147_E0.5240.91
44_L47_D0.5240.91
608_P615_R0.5230.91
454_L465_V0.5220.91
263_E270_Q0.5210.91
172_M271_W0.5210.91
586_V589_A0.5200.91
495_T513_V0.5200.91
144_T151_K0.5180.91
132_R139_E0.5170.91
348_R352_L0.5160.91
79_L83_A0.5150.91
220_E233_T0.5150.91
410_L494_S0.5140.91
75_L190_L0.5140.91
496_L516_G0.5130.90
316_Y323_L0.5120.90
210_G215_L0.5110.90
473_L525_R0.5110.90
57_H277_A0.5100.90
44_L48_K0.5090.90
426_E432_A0.5090.90
152_Y155_L0.5080.90
587_H590_L0.5080.90
602_L605_G0.5080.90
492_L508_S0.5070.90
153_R156_L0.5070.90
605_G608_P0.5060.90
596_R615_R0.5060.90
21_R338_G0.5050.90
334_W360_Q0.5050.90
360_Q363_L0.5050.90
316_Y345_I0.5050.90
588_S591_I0.5040.90
583_D587_H0.5040.90
491_C495_T0.5030.90
394_R399_G0.5030.90
141_S144_T0.5020.90
187_A191_A0.5020.90
206_P281_A0.5010.89
545_Y556_T0.5000.89
158_S161_S0.5000.89
421_K428_D0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1bl0A 1 0.1419 100 0.809 Contact Map
3oioA 1 0.1459 100 0.811 Contact Map
3oouA 1 0.1367 100 0.811 Contact Map
3mn2A 1 0.138 100 0.812 Contact Map
3gbgA 1 0.3298 100 0.812 Contact Map
3mklA 1 0.1445 100 0.815 Contact Map
3w6vA 1 0.1406 100 0.815 Contact Map
2k9sA 1 0.138 100 0.816 Contact Map
3lsgA 2 0.1327 100 0.819 Contact Map
1d5yA 1 0.1419 100 0.82 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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