YESO - BACSU - GREMLIN Contacts

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YESO - Putative ABC transporter substrate-binding protein YesO

UniProt:	O31518	Sequences: MKKICYVLLSLVCVFLFSGCSAGEEASGKKEDVTLRIAWWGGQPRHDYTTKVIELYEKKNPHVHIEAEFANWDDYWKKLAPMSAAGQLPDVIQMDTAYLAQYGKKNQLEDLTPYTKDGTIDVSSIDENMLSGGKIDNKLYGFTLGVNVLSVIANEDLLKKAGVSINQENWTWEDYEKLAYDLQEKAGVYGSNGMHPPDIFFPYYLRTKGERFYKEDGTGLAYQDDQLFVDYFERQLRLVKAKTSPTPDESAQIKGMEDDFIVKGKSAITWNYSNQYLGFARLTDSPLSLYLPPEQMQEKALTLKPSMLFSIPKSSEHKKEAAKFINFFVNNEEANQLIKGERGVPVSDKVADAIKPKLNEEETNIVEYVETASKNISKADPPEPVGSAEVIKLLKDTSDQILYQKVSPEKAAKTFRKKANEILERNN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	427 (395)
Sequences:	30288 (24233)
Seq/√Len:	1219.3

ECOLI - UGPB YCJN MALE YDCS YNJB POTF POTD THIB
BACSU - YESO YURO CYCB ARAN MDXE YTCQ MSME LIPO
HALSA - Q9HHQ8 Q9HP00 Q9HR87 Q9HNZ3 Q9HMT5 Q9HR04
SULSO - Q97YY1 Q97ZC3 Q97UZ1 Q97VC2 Q97UF5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
34_T	66_E	3.721	1.00
407_S	410_K	3.467	1.00
109_E	318_K	3.301	1.00
156_D	286_P	3.227	1.00
229_V	409_E	3.164	1.00
236_L	240_K	3.000	1.00
110_D	138_K	2.852	1.00
34_T	64_H	2.839	1.00
36_R	66_E	2.802	1.00
155_E	288_S	2.796	1.00
233_E	237_R	2.718	1.00
60_N	323_K	2.610	1.00
180_Y	241_A	2.605	1.00
176_E	237_R	2.556	1.00
155_E	159_K	2.461	1.00
50_T	54_E	2.408	1.00
237_R	241_A	2.401	1.00
409_E	413_K	2.361	1.00
171_T	174_D	2.349	1.00
63_V	320_E	2.340	1.00
55_L	58_K	2.340	1.00
153_A	288_S	2.307	1.00
74_D	77_K	2.300	1.00
57_E	64_H	2.253	1.00
413_K	417_K	2.204	1.00
177_K	181_D	2.186	1.00
323_K	326_N	2.184	1.00
56_Y	323_K	2.168	1.00
158_L	268_I	2.126	1.00
134_K	139_L	2.101	1.00
112_T	138_K	2.083	1.00
416_R	420_N	2.066	1.00
223_Q	413_K	2.050	1.00
36_R	68_E	2.043	1.00
317_H	320_E	2.029	1.00
127_E	131_S	2.028	1.00
12_V	15_F	2.021	1.00
330_N	333_E	2.010	1.00
180_Y	184_E	2.009	1.00
54_E	58_K	2.008	1.00
163_V	178_L	1.996	1.00
32_D	64_H	1.993	1.00
51_K	54_E	1.992	1.00
406_V	414_T	1.991	1.00
225_D	230_D	1.986	1.00
55_L	327_F	1.971	1.00
174_D	177_K	1.939	1.00
400_Q	405_K	1.891	1.00
252_Q	256_M	1.873	1.00
57_E	60_N	1.866	1.00
156_D	160_K	1.863	1.00
38_A	82_M	1.854	1.00
233_E	408_P	1.853	1.00
55_L	59_K	1.825	1.00
230_D	233_E	1.825	1.00
124_S	349_K	1.823	1.00
131_S	134_K	1.797	1.00
90_D	317_H	1.786	1.00
108_L	310_S	1.780	1.00
181_D	185_K	1.758	1.00
214_K	218_T	1.757	1.00
400_Q	406_V	1.749	1.00
366_V	370_E	1.730	1.00
13_C	16_L	1.729	1.00
177_K	180_Y	1.722	1.00
114_Y	322_A	1.682	1.00
92_I	312_P	1.680	1.00
410_K	414_T	1.668	1.00
53_I	57_E	1.642	1.00
319_K	323_K	1.632	1.00
33_V	320_E	1.629	1.00
141_G	308_L	1.615	1.00
173_E	176_E	1.614	1.00
401_I	411_A	1.598	1.00
176_E	241_A	1.593	1.00
233_E	409_E	1.592	1.00
229_V	408_P	1.581	1.00
53_I	324_F	1.573	1.00
55_L	336_Q	1.564	1.00
54_E	57_E	1.562	1.00
414_T	418_K	1.562	1.00
392_K	396_D	1.558	1.00
133_G	308_L	1.545	1.00
192_N	266_S	1.536	1.00
335_N	339_K	1.530	1.00
151_V	290_Y	1.523	1.00
229_V	233_E	1.523	1.00
164_S	167_Q	1.519	1.00
176_E	180_Y	1.498	1.00
56_Y	60_N	1.493	1.00
153_A	290_Y	1.492	1.00
393_L	418_K	1.486	1.00
157_L	267_A	1.479	1.00
176_E	238_L	1.479	1.00
413_K	416_R	1.477	1.00
410_K	413_K	1.461	1.00
155_E	286_P	1.446	1.00
110_D	113_P	1.445	1.00
157_L	182_L	1.438	1.00
83_S	88_L	1.435	1.00
78_K	82_M	1.431	1.00
414_T	417_K	1.424	1.00
173_E	177_K	1.408	1.00
46_H	50_T	1.403	1.00
32_D	62_H	1.403	1.00
236_L	401_I	1.397	1.00
260_F	265_K	1.395	1.00
56_Y	63_V	1.392	1.00
331_N	335_N	1.390	1.00
223_Q	416_R	1.382	1.00
109_E	313_K	1.376	1.00
182_L	267_A	1.374	1.00
33_V	317_H	1.373	1.00
180_Y	243_T	1.373	1.00
234_R	237_R	1.372	1.00
311_I	325_I	1.361	1.00
51_K	55_L	1.357	1.00
401_I	408_P	1.355	1.00
56_Y	327_F	1.345	1.00
333_E	336_Q	1.341	1.00
397_T	414_T	1.332	1.00
397_T	406_V	1.330	1.00
234_R	238_L	1.326	1.00
179_A	268_I	1.321	1.00
56_Y	324_F	1.318	1.00
39_W	67_A	1.306	1.00
159_K	165_I	1.298	1.00
315_S	318_K	1.293	1.00
183_Q	190_G	1.290	1.00
237_R	240_K	1.288	1.00
71_N	74_D	1.261	1.00
103_G	140_Y	1.258	1.00
226_Q	230_D	1.258	1.00
151_V	268_I	1.253	1.00
53_I	67_A	1.244	1.00
367_E	370_E	1.238	1.00
63_V	323_K	1.236	1.00
406_V	411_A	1.233	1.00
150_S	289_L	1.232	1.00
161_A	182_L	1.231	1.00
261_I	287_L	1.224	1.00
397_T	400_Q	1.221	1.00
176_E	234_R	1.221	1.00
133_G	139_L	1.218	1.00
47_D	50_T	1.212	1.00
173_E	296_M	1.211	1.00
10_S	14_V	1.210	1.00
336_Q	340_G	1.209	1.00
91_V	325_I	1.203	1.00
327_F	333_E	1.196	1.00
417_K	420_N	1.192	1.00
370_E	374_K	1.177	1.00
315_S	321_A	1.175	1.00
163_V	181_D	1.171	1.00
20_C	23_G	1.168	1.00
158_L	163_V	1.167	1.00
370_E	373_S	1.161	1.00
106_N	313_K	1.159	1.00
320_E	323_K	1.156	1.00
94_M	310_S	1.156	1.00
20_C	24_E	1.142	1.00
183_Q	243_T	1.140	1.00
397_T	415_F	1.140	1.00
13_C	17_F	1.132	1.00
178_L	181_D	1.129	1.00
349_K	352_D	1.125	1.00
91_V	321_A	1.122	1.00
179_A	243_T	1.120	1.00
322_A	326_N	1.117	1.00
47_D	51_K	1.115	1.00
154_N	157_L	1.109	1.00
396_D	418_K	1.106	1.00
259_D	263_K	1.102	1.00
324_F	328_F	1.101	1.00
188_V	265_K	1.098	1.00
175_Y	179_A	1.086	1.00
400_Q	414_T	1.081	1.00
324_F	327_F	1.081	1.00
347_S	350_V	1.079	1.00
167_Q	174_D	1.075	1.00
60_N	63_V	1.075	1.00
157_L	161_A	1.070	1.00
88_L	312_P	1.066	1.00
113_P	116_K	1.057	1.00
33_V	62_H	1.054	1.00
35_L	324_F	1.054	1.00
390_V	419_A	1.054	1.00
16_L	19_G	1.051	1.00
311_I	322_A	1.044	1.00
90_D	315_S	1.039	1.00
14_V	17_F	1.039	1.00
229_V	412_A	1.038	1.00
130_L	134_K	1.037	1.00
158_L	178_L	1.035	1.00
56_Y	320_E	1.034	1.00
313_K	318_K	1.033	1.00
103_G	135_I	1.030	1.00
393_L	396_D	1.029	1.00
211_R	215_E	1.029	1.00
159_K	164_S	1.029	1.00
406_V	410_K	1.029	1.00
256_M	259_D	1.028	1.00
79_L	92_I	1.026	1.00
220_L	420_N	1.021	1.00
109_E	315_S	1.018	1.00
157_L	160_K	1.014	1.00
236_L	408_P	1.013	1.00
175_Y	268_I	1.012	1.00
230_D	234_R	1.010	1.00
157_L	188_V	1.007	1.00
318_K	322_A	1.006	1.00
37_I	309_F	1.006	1.00
331_N	349_K	1.000	1.00
181_D	184_E	0.999	1.00
205_L	210_E	0.996	1.00
353_A	356_P	0.992	1.00
65_I	324_F	0.987	1.00
189_Y	246_T	0.987	1.00
312_P	315_S	0.987	1.00
163_V	182_L	0.986	1.00
12_V	16_L	0.985	1.00
311_I	321_A	0.982	1.00
91_V	324_F	0.977	1.00
86_G	314_S	0.977	1.00
175_Y	191_S	0.972	1.00
92_I	310_S	0.972	1.00
53_I	65_I	0.967	1.00
59_K	330_N	0.961	1.00
233_E	236_L	0.960	1.00
211_R	214_K	0.959	1.00
178_L	268_I	0.956	1.00
271_N	275_Q	0.956	1.00
122_V	130_L	0.950	1.00
161_A	185_K	0.950	1.00
10_S	16_L	0.949	1.00
260_F	266_S	0.949	1.00
232_F	401_I	0.949	1.00
11_L	14_V	0.946	1.00
208_K	230_D	0.946	1.00
332_E	335_N	0.946	1.00
55_L	332_E	0.945	1.00
83_S	107_Q	0.942	1.00
38_A	89_P	0.933	1.00
225_D	229_V	0.932	1.00
397_T	418_K	0.928	1.00
51_K	336_Q	0.924	1.00
389_E	392_K	0.917	1.00
156_D	159_K	0.917	1.00
372_A	375_N	0.916	1.00
336_Q	339_K	0.916	1.00
124_S	347_S	0.916	1.00
396_D	400_Q	0.910	1.00
78_K	81_P	0.909	1.00
393_L	397_T	0.905	1.00
278_G	281_R	0.905	1.00
10_S	13_C	0.900	1.00
51_K	340_G	0.898	1.00
221_A	224_D	0.896	1.00
52_V	55_L	0.895	1.00
411_A	415_F	0.893	1.00
81_P	85_A	0.881	1.00
130_L	139_L	0.881	1.00
121_D	326_N	0.878	1.00
38_A	70_A	0.877	1.00
112_T	116_K	0.876	1.00
252_Q	255_G	0.876	1.00
367_E	371_T	0.875	1.00
393_L	415_F	0.875	1.00
160_K	188_V	0.869	1.00
127_E	348_D	0.866	1.00
126_D	348_D	0.861	1.00
76_W	98_Y	0.859	1.00
35_L	320_E	0.858	1.00
161_A	165_I	0.857	1.00
332_E	336_Q	0.856	1.00
176_E	243_T	0.855	1.00
407_S	411_A	0.854	1.00
152_I	271_N	0.854	1.00
114_Y	319_K	0.853	1.00
144_L	309_F	0.850	1.00
121_D	124_S	0.850	1.00
48_Y	51_K	0.846	1.00
412_A	416_R	0.845	1.00
125_I	329_V	0.844	1.00
120_I	123_S	0.843	1.00
37_I	91_V	0.842	1.00
141_G	310_S	0.840	1.00
115_T	139_L	0.837	1.00
59_K	332_E	0.837	1.00
161_A	181_D	0.837	1.00
11_L	15_F	0.835	1.00
55_L	333_E	0.835	1.00
92_I	108_L	0.832	1.00
159_K	286_P	0.832	1.00
321_A	325_I	0.830	1.00
397_T	411_A	0.830	1.00
166_N	174_D	0.829	1.00
220_L	416_R	0.828	1.00
109_E	312_P	0.826	1.00
20_C	25_E	0.824	1.00
103_G	108_L	0.822	1.00
392_K	395_K	0.822	1.00
112_T	139_L	0.821	1.00
335_N	353_A	0.820	1.00
57_E	62_H	0.820	1.00
238_L	243_T	0.819	1.00
335_N	350_V	0.811	1.00
20_C	26_A	0.810	1.00
127_E	130_L	0.810	1.00
52_V	333_E	0.809	1.00
242_K	246_T	0.808	1.00
201_F	205_L	0.803	1.00
153_A	165_I	0.802	1.00
108_L	140_Y	0.799	1.00
70_A	78_K	0.798	1.00
112_T	134_K	0.795	1.00
412_A	415_F	0.789	1.00
158_L	182_L	0.787	1.00
184_E	187_G	0.781	1.00
179_A	190_G	0.779	1.00
57_E	65_I	0.779	1.00
59_K	327_F	0.779	1.00
134_K	137_N	0.777	1.00
311_I	315_S	0.775	1.00
179_A	183_Q	0.773	1.00
33_V	63_V	0.772	1.00
110_D	140_Y	0.772	1.00
35_L	317_H	0.770	1.00
319_K	322_A	0.768	1.00
259_D	262_V	0.767	1.00
11_L	16_L	0.765	1.00
255_G	258_D	0.760	1.00
232_F	412_A	0.760	1.00
232_F	411_A	0.759	1.00
17_F	20_C	0.759	1.00
154_N	286_P	0.754	1.00
176_E	179_A	0.753	1.00
183_Q	189_Y	0.751	1.00
82_M	87_Q	0.751	1.00
109_E	114_Y	0.749	1.00
62_H	323_K	0.749	1.00
109_E	311_I	0.747	1.00
245_P	248_D	0.745	1.00
363_T	366_V	0.743	1.00
371_T	374_K	0.742	1.00
150_S	368_Y	0.741	1.00
368_Y	372_A	0.740	1.00
109_E	113_P	0.739	1.00
350_V	353_A	0.737	1.00
348_D	352_D	0.722	1.00
394_L	415_F	0.721	1.00
183_Q	242_K	0.719	1.00
128_N	131_S	0.718	1.00
396_D	399_D	0.717	1.00
369_V	373_S	0.717	1.00
178_L	182_L	0.715	1.00
214_K	217_G	0.714	1.00
113_P	322_A	0.711	1.00
387_S	391_I	0.708	1.00
52_V	327_F	0.708	1.00
19_G	23_G	0.705	1.00
161_A	188_V	0.704	1.00
116_K	122_V	0.704	1.00
35_L	321_A	0.699	1.00
100_A	104_K	0.699	1.00
214_K	221_A	0.698	1.00
75_Y	79_L	0.698	1.00
156_D	285_S	0.694	1.00
235_Q	239_V	0.694	1.00
164_S	178_L	0.690	1.00
102_Y	108_L	0.690	1.00
245_P	260_F	0.687	1.00
208_K	234_R	0.686	1.00
172_W	234_R	0.686	1.00
205_L	231_Y	0.679	1.00
161_A	178_L	0.678	1.00
101_Q	105_K	0.677	1.00
23_G	26_A	0.676	1.00
255_G	259_D	0.672	1.00
154_N	285_S	0.672	1.00
236_L	239_V	0.671	1.00
189_Y	245_P	0.671	1.00
91_V	309_F	0.669	1.00
57_E	63_V	0.667	1.00
161_A	267_A	0.667	1.00
411_A	414_T	0.666	1.00
351_A	354_I	0.662	1.00
192_N	257_E	0.661	1.00
391_I	395_K	0.658	1.00
19_G	22_A	0.657	1.00
408_P	412_A	0.657	1.00
77_K	81_P	0.656	1.00
99_L	141_G	0.655	1.00
109_E	322_A	0.650	1.00
331_N	347_S	0.650	1.00
182_L	268_I	0.647	1.00
114_Y	318_K	0.647	1.00
38_A	68_E	0.647	1.00
222_Y	419_A	0.647	1.00
318_K	321_A	0.647	1.00
185_K	188_V	0.646	1.00
172_W	176_E	0.645	1.00
257_E	269_T	0.644	1.00
153_A	158_L	0.642	1.00
203_Y	206_R	0.642	1.00
180_Y	183_Q	0.640	1.00
277_L	281_R	0.639	1.00
276_Y	280_A	0.639	1.00
152_I	289_L	0.639	1.00
83_S	312_P	0.638	1.00
160_K	185_K	0.636	1.00
32_D	60_N	0.634	1.00
401_I	406_V	0.633	1.00
98_Y	101_Q	0.633	1.00
113_P	138_K	0.632	1.00
409_E	412_A	0.631	1.00
8_L	11_L	0.631	1.00
365_I	369_V	0.630	1.00
8_L	13_C	0.630	1.00
15_F	18_S	0.627	1.00
371_T	375_N	0.626	1.00
113_P	117_D	0.623	1.00
88_L	314_S	0.620	1.00
9_L	12_V	0.620	1.00
215_E	218_T	0.620	1.00
94_M	102_Y	0.619	1.00
124_S	331_N	0.619	1.00
60_N	320_E	0.619	1.00
52_V	328_F	0.618	1.00
222_Y	228_F	0.617	1.00
74_D	78_K	0.614	1.00
109_E	314_S	0.611	1.00
182_L	188_V	0.611	1.00
9_L	13_C	0.611	1.00
22_A	25_E	0.610	1.00
260_F	263_K	0.609	1.00
16_L	20_C	0.609	1.00
125_I	130_L	0.608	1.00
224_D	229_V	0.608	1.00
31_E	62_H	0.607	1.00
399_D	403_Y	0.607	1.00
202_P	206_R	0.606	1.00
37_I	67_A	0.606	1.00
99_L	103_G	0.606	1.00
80_A	101_Q	0.604	1.00
126_D	351_A	0.604	1.00
205_L	228_F	0.604	1.00
8_L	12_V	0.603	1.00
126_D	129_M	0.600	1.00
309_F	325_I	0.599	1.00
30_K	62_H	0.599	1.00
8_L	14_V	0.597	1.00
10_S	15_F	0.597	1.00
52_V	336_Q	0.595	1.00
60_N	324_F	0.593	1.00
159_K	162_G	0.592	1.00
224_D	228_F	0.592	1.00
122_V	134_K	0.592	1.00
133_G	141_G	0.590	1.00
32_D	63_V	0.589	1.00
152_I	276_Y	0.589	1.00
68_E	78_K	0.588	1.00
388_A	392_K	0.587	1.00
236_L	407_S	0.585	1.00
76_W	101_Q	0.585	1.00
60_N	327_F	0.583	1.00
21_S	24_E	0.582	1.00
386_G	389_E	0.582	1.00
183_Q	187_G	0.582	1.00
179_A	238_L	0.582	1.00
111_L	325_I	0.581	1.00
14_V	18_S	0.581	1.00
294_E	300_A	0.580	1.00
151_V	270_W	0.580	1.00
256_M	260_F	0.579	1.00
408_P	411_A	0.579	1.00
36_R	82_M	0.578	1.00
361_E	364_N	0.577	1.00
182_L	185_K	0.577	1.00
262_V	282_L	0.577	1.00
68_E	82_M	0.576	1.00
240_K	243_T	0.575	1.00
366_V	369_V	0.574	1.00
56_Y	65_I	0.574	1.00
18_S	22_A	0.573	1.00
36_R	90_D	0.573	1.00
35_L	315_S	0.568	1.00
326_N	330_N	0.567	1.00
154_N	264_G	0.566	1.00
180_Y	237_R	0.566	1.00
147_N	307_M	0.565	1.00
37_I	53_I	0.563	1.00
6_Y	9_L	0.563	1.00
239_V	244_S	0.563	1.00
33_V	60_N	0.562	1.00
7_V	14_V	0.561	1.00
365_I	368_Y	0.559	1.00
364_N	367_E	0.559	1.00
112_T	322_A	0.558	1.00
397_T	401_I	0.558	1.00
18_S	21_S	0.558	1.00
77_K	80_A	0.558	1.00
49_T	52_V	0.557	1.00
119_T	326_N	0.557	1.00
99_L	108_L	0.555	1.00
348_D	351_A	0.555	1.00
152_I	287_L	0.555	1.00
106_N	109_E	0.554	1.00
221_A	416_R	0.553	1.00
322_A	325_I	0.553	1.00
156_D	264_G	0.552	1.00
17_F	22_A	0.552	1.00
231_Y	235_Q	0.551	1.00
82_M	89_P	0.547	1.00
251_A	260_F	0.546	1.00
363_T	367_E	0.546	1.00
258_D	262_V	0.545	1.00
35_L	91_V	0.545	1.00
183_Q	188_V	0.545	1.00
7_V	12_V	0.544	1.00
103_G	106_N	0.544	1.00
64_H	67_A	0.543	1.00
35_L	90_D	0.542	1.00
389_E	393_L	0.541	1.00
165_I	174_D	0.540	1.00
224_D	416_R	0.540	1.00
280_A	287_L	0.539	1.00
278_G	282_L	0.536	1.00
211_R	221_A	0.534	1.00
164_S	174_D	0.534	1.00
107_Q	110_D	0.534	1.00
229_V	413_K	0.532	1.00
398_S	402_L	0.531	1.00
309_F	328_F	0.530	1.00
317_H	321_A	0.530	1.00
35_L	65_I	0.528	1.00
76_W	102_Y	0.528	1.00
369_V	372_A	0.527	1.00
30_K	33_V	0.526	1.00
258_D	271_N	0.526	1.00
21_S	25_E	0.526	1.00
72_W	75_Y	0.525	1.00
13_C	19_G	0.524	1.00
68_E	89_P	0.524	1.00
165_I	290_Y	0.523	1.00
44_P	47_D	0.523	1.00
114_Y	117_D	0.523	1.00
70_A	75_Y	0.522	1.00
196_P	252_Q	0.522	1.00
400_Q	411_A	0.522	1.00
90_D	318_K	0.522	1.00
130_L	143_T	0.521	1.00
210_E	228_F	0.521	1.00
104_K	136_D	0.521	1.00
192_N	260_F	0.521	1.00
230_D	295_Q	0.520	1.00
142_F	325_I	0.520	1.00
184_E	188_V	0.519	1.00
364_N	368_Y	0.519	1.00
174_D	178_L	0.518	1.00
8_L	15_F	0.518	1.00
223_Q	412_A	0.517	1.00
158_L	165_I	0.516	1.00
163_V	267_A	0.515	1.00
158_L	267_A	0.515	1.00
415_F	419_A	0.515	1.00
334_A	346_V	0.513	1.00
59_K	62_H	0.512	1.00
6_Y	10_S	0.512	1.00
48_Y	52_V	0.510	1.00
95_D	307_M	0.509	1.00
304_K	308_L	0.509	1.00
100_A	135_I	0.508	1.00
261_I	269_T	0.507	1.00
60_N	65_I	0.507	1.00
6_Y	16_L	0.506	1.00
368_Y	371_T	0.506	1.00
90_D	316_E	0.506	1.00
36_R	89_P	0.505	1.00
6_Y	15_F	0.505	1.00
38_A	75_Y	0.504	1.00
6_Y	13_C	0.504	1.00
206_R	211_R	0.504	1.00
15_F	19_G	0.504	1.00
120_I	326_N	0.504	1.00
165_I	178_L	0.504	1.00
115_T	322_A	0.503	1.00
80_A	84_A	0.502	1.00
37_I	93_Q	0.502	1.00
122_V	125_I	0.501	1.00
151_V	175_Y	0.500	1.00
288_S	291_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r6kA	1	0.9274	100	0.127	Contact Map
4r2fA	1	0.8782	100	0.147	Contact Map
3uorA	1	0.8923	100	0.147	Contact Map
4r9fA	1	0.8876	100	0.16	Contact Map
4mfiA	1	0.9063	100	0.163	Contact Map
4ovjA	1	0.8993	100	0.176	Contact Map
3vxbA	1	0.8806	100	0.197	Contact Map
2w7yA	1	0.8806	100	0.202	Contact Map
3k01A	1	0.897	100	0.213	Contact Map
4r6hA	1	0.8806	100	0.213	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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