GREMLIN Database
YESM - Sensor histidine kinase YesM
UniProt: O31516 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 577 (527)
Sequences: 12335 (10961)
Seq/√Len: 477.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
516_E565_R4.7051.00
559_E562_K4.2821.00
541_R545_S3.9231.00
510_C569_T3.8031.00
517_D521_G3.7861.00
370_N373_K3.6281.00
464_D503_Q3.6171.00
512_C569_T3.5081.00
556_I566_I3.3881.00
523_D526_I3.3331.00
514_T565_R3.3261.00
503_Q514_T3.2821.00
462_T499_A3.2801.00
557_H565_R3.2631.00
505_K512_C3.0511.00
558_S564_T3.0121.00
347_D350_G2.9971.00
462_T501_R2.9711.00
555_R567_V2.9571.00
501_R516_E2.9401.00
512_C567_V2.8851.00
367_M370_N2.8711.00
522_M526_I2.8691.00
436_T439_E2.8521.00
514_T567_V2.8451.00
503_Q516_E2.8121.00
374_Q377_I2.7781.00
499_A518_N2.7331.00
366_L370_N2.7261.00
558_S562_K2.6561.00
363_I366_L2.6541.00
327_S332_G2.6451.00
540_I554_L2.5771.00
506_K572_C2.5101.00
527_L556_I2.4591.00
220_D224_N2.4591.00
367_M371_V2.4531.00
17_K347_D2.4461.00
460_K499_A2.4371.00
505_K514_T2.4201.00
557_H567_V2.3461.00
360_M363_I2.3211.00
365_E369_E2.3091.00
444_V483_A2.2971.00
544_I568_I2.2811.00
478_T544_I2.2431.00
498_C518_N2.2281.00
479_L513_I2.1821.00
523_D560_H2.1491.00
522_M564_T2.1441.00
345_T350_G2.0811.00
264_Q271_S2.0761.00
464_D501_R2.0671.00
513_I568_I2.0121.00
374_Q378_K1.9941.00
478_T543_R1.9621.00
219_A273_Y1.9551.00
558_S561_E1.9511.00
34_Y38_Q1.9411.00
359_M363_I1.9401.00
375_L378_K1.9381.00
362_R365_E1.9241.00
346_Q350_G1.8691.00
507_A512_C1.8561.00
527_L558_S1.8551.00
356_F359_M1.8281.00
545_S550_E1.8141.00
126_D130_S1.8041.00
366_L369_E1.7851.00
504_A513_I1.7821.00
336_G361_K1.7611.00
405_A413_I1.7441.00
522_M527_L1.7411.00
371_V375_L1.7241.00
524_G528_E1.7191.00
421_G424_L1.7091.00
433_D472_C1.7081.00
375_L379_E1.7041.00
369_E373_K1.7021.00
402_N410_Q1.7011.00
469_V504_A1.7001.00
465_I504_A1.6931.00
474_I478_T1.6931.00
482_L566_I1.6901.00
438_Q442_D1.6851.00
364_N367_M1.6551.00
550_E555_R1.6551.00
442_D445_R1.6501.00
364_N368_E1.6221.00
182_H188_G1.6201.00
483_A502_I1.6071.00
482_L515_V1.6061.00
258_Y275_V1.5991.00
556_I564_T1.5911.00
376_I379_E1.5801.00
321_L325_M1.5791.00
123_H193_L1.5721.00
328_V360_M1.5641.00
466_D469_V1.5551.00
544_I554_L1.5551.00
410_Q413_I1.5461.00
314_I317_P1.5301.00
524_G527_L1.5291.00
438_Q471_H1.5271.00
468_E506_K1.5231.00
482_L554_L1.5231.00
336_G357_T1.5041.00
368_E372_E1.4981.00
213_V280_Q1.4971.00
393_F477_L1.4891.00
399_E403_W1.4861.00
482_L537_L1.4791.00
311_A315_T1.4771.00
402_N414_S1.4741.00
387_A393_F1.4641.00
148_E152_R1.4641.00
363_I367_M1.4621.00
382_L386_Q1.4611.00
539_N543_R1.4441.00
217_M275_V1.4431.00
334_E364_N1.4301.00
307_G311_A1.4251.00
262_Y271_S1.4171.00
176_R195_Q1.4141.00
102_K106_W1.4091.00
543_R547_T1.4071.00
443_I476_K1.4061.00
544_I549_G1.4061.00
370_N374_Q1.3981.00
544_I570_I1.3961.00
99_Y103_Q1.3951.00
312_N316_E1.3901.00
449_T453_F1.3821.00
380_T384_A1.3771.00
41_F45_D1.3741.00
211_D214_G1.3731.00
173_I177_Q1.3681.00
60_S64_E1.3651.00
56_L274_N1.3601.00
478_T540_I1.3541.00
522_M558_S1.3411.00
474_I477_L1.3361.00
471_H474_I1.3221.00
555_R569_T1.3081.00
151_K155_A1.3011.00
437_I513_I1.3001.00
247_G262_Y1.2991.00
45_D49_Y1.2971.00
426_N435_V1.2901.00
322_V351_M1.2861.00
325_M356_F1.2811.00
361_K365_E1.2781.00
394_L420_L1.2761.00
373_K377_I1.2751.00
200_Q203_R1.2721.00
399_E402_N1.2701.00
29_S33_V1.2611.00
438_Q470_K1.2571.00
322_V326_K1.2491.00
414_S418_E1.2421.00
535_I539_N1.2311.00
445_R463_L1.2271.00
105_L109_L1.2251.00
221_Q269_N1.2221.00
400_S404_L1.2221.00
393_F397_T1.2211.00
353_N356_F1.2131.00
325_M328_V1.2011.00
448_M480_Q1.1961.00
437_I474_I1.1951.00
385_L389_I1.1921.00
146_Q149_V1.1921.00
437_I511_V1.1881.00
121_S195_Q1.1871.00
441_A465_I1.1801.00
353_N357_T1.1771.00
152_R155_A1.1751.00
393_F396_N1.1751.00
541_R554_L1.1741.00
360_M364_N1.1721.00
64_E265_S1.1711.00
35_S39_Y1.1691.00
511_V572_C1.1681.00
358_V362_R1.1641.00
481_P484_E1.1611.00
550_E569_T1.1501.00
217_M273_Y1.1481.00
215_D229_A1.1461.00
167_G170_P1.1461.00
447_Y480_Q1.1451.00
400_S409_Q1.1431.00
405_A410_Q1.1401.00
257_R278_F1.1381.00
467_D470_K1.1381.00
442_D446_H1.1361.00
445_R449_T1.1231.00
475_P547_T1.1191.00
469_V511_V1.1181.00
349_A352_L1.1171.00
80_D108_Q1.1151.00
448_M461_F1.1131.00
482_L568_I1.1131.00
278_F282_F1.1081.00
349_A353_N1.1031.00
324_A337_V1.0991.00
37_V41_F1.0981.00
372_E376_I1.0961.00
106_W110_A1.0951.00
368_E371_V1.0931.00
52_S56_L1.0931.00
202_I205_V1.0881.00
125_I131_E1.0861.00
478_T568_I1.0851.00
102_K105_L1.0811.00
396_N400_S1.0801.00
466_D505_K1.0761.00
74_S194_I1.0751.00
377_I381_E1.0751.00
68_K71_E1.0701.00
474_I543_R1.0641.00
39_Y42_H1.0641.00
66_E69_K1.0621.00
423_L426_N1.0591.00
225_L228_T1.0581.00
352_L356_F1.0561.00
180_S188_G1.0561.00
441_A504_A1.0551.00
350_G353_N1.0481.00
495_T518_N1.0461.00
464_D505_K1.0451.00
459_L487_I1.0371.00
60_S263_L1.0361.00
66_E70_I1.0351.00
143_Q146_Q1.0351.00
286_S290_T1.0351.00
47_Q50_R1.0331.00
460_K497_P1.0331.00
489_Y518_N1.0331.00
393_F481_P1.0321.00
61_E65_D1.0201.00
49_Y53_S1.0171.00
126_D132_Y1.0161.00
148_E151_K1.0131.00
125_I193_L1.0121.00
392_H396_N1.0091.00
70_I74_S1.0041.00
536_G540_I1.0021.00
538_W542_E1.0011.00
26_M29_S0.9971.00
359_M362_R0.9951.00
173_I176_R0.9921.00
350_G354_R0.9921.00
325_M352_L0.9901.00
151_K154_K0.9901.00
101_M104_E0.9881.00
377_I380_T0.9871.00
38_Q42_H0.9851.00
328_V356_F0.9821.00
483_A500_I0.9821.00
64_E68_K0.9821.00
379_E383_K0.9811.00
479_L515_V0.9781.00
542_E545_S0.9771.00
325_M329_Q0.9771.00
53_S57_R0.9711.00
150_F154_K0.9691.00
517_D563_G0.9681.00
401_I406_K0.9641.00
172_L175_A0.9631.00
70_I73_V0.9571.00
153_A191_M0.9571.00
203_R206_P0.9561.00
198_V202_I0.9541.00
356_F360_M0.9531.00
401_I410_Q0.9511.00
215_D275_V0.9501.00
60_S265_S0.9451.00
56_L60_S0.9451.00
250_L257_R0.9451.00
280_Q283_A0.9451.00
327_S335_A0.9431.00
385_L390_N0.9431.00
326_K329_Q0.9431.00
476_K480_Q0.9421.00
329_Q333_I0.9411.00
318_I352_L0.9411.00
50_R53_S0.9401.00
394_L398_L0.9381.00
520_P530_T0.9381.00
404_L409_Q0.9371.00
25_I29_S0.9301.00
410_Q414_S0.9241.00
290_T294_T0.9231.00
507_A569_T0.9211.00
452_R487_I0.9191.00
177_Q180_S0.9191.00
40_A44_Y0.9181.00
131_E134_A0.9181.00
43_V47_Q0.9161.00
448_M483_A0.9141.00
419_S449_T0.9131.00
365_E368_E0.9051.00
15_K312_N0.9031.00
162_W165_L0.9021.00
385_L388_Q0.9001.00
45_D48_I0.8981.00
400_S403_W0.8981.00
329_Q358_V0.8971.00
48_I52_S0.8951.00
543_R546_L0.8941.00
438_Q504_A0.8931.00
390_N396_N0.8911.00
74_S78_I0.8911.00
336_G364_N0.8871.00
285_I289_K0.8861.00
439_E442_D0.8781.00
522_M528_E0.8781.00
537_L556_I0.8771.00
247_G251_I0.8741.00
331_S335_A0.8741.00
418_E422_F0.8721.00
507_A510_C0.8721.00
497_P518_N0.8721.00
378_K381_E0.8631.00
135_G138_S0.8631.00
326_K330_H0.8631.00
154_K188_G0.8631.00
82_Q85_R0.8631.00
326_K351_M0.8621.00
54_E57_R0.8601.00
199_K203_R0.8601.00
516_E559_E0.8601.00
345_T353_N0.8601.00
448_M487_I0.8601.00
103_Q107_D0.8571.00
260_I275_V0.8571.00
413_I417_V0.8571.00
522_M556_I0.8561.00
253_K256_K0.8511.00
172_L176_R0.8501.00
371_V374_Q0.8491.00
42_H45_D0.8481.00
374_Q379_E0.8471.00
141_L144_Q0.8451.00
318_I322_V0.8451.00
259_F278_F0.8421.00
396_N403_W0.8421.00
441_A479_L0.8411.00
23_S29_S0.8401.00
313_S316_E0.8401.00
351_M354_R0.8381.00
417_V421_G0.8381.00
328_V331_S0.8371.00
265_S272_Y0.8361.00
38_Q41_F0.8361.00
394_L397_T0.8341.00
554_L568_I0.8341.00
524_G558_S0.8331.00
477_L539_N0.8331.00
50_R54_E0.8321.00
297_L301_C0.8321.00
352_L359_M0.8301.00
395_Y413_I0.8291.00
501_R518_N0.8291.00
332_G335_A0.8261.00
216_I274_N0.8261.00
555_R568_I0.8261.00
190_G193_L0.8211.00
345_T348_E0.8211.00
509_G572_C0.8201.00
175_A178_I0.8181.00
224_N227_Y0.8161.00
357_T360_M0.8161.00
98_Q101_M0.8151.00
170_P173_I0.8141.00
411_K415_K0.8141.00
399_E421_G0.8141.00
406_K410_Q0.8131.00
277_P280_Q0.8121.00
472_C476_K0.8111.00
286_S289_K0.8101.00
474_I546_L0.8091.00
218_I272_Y0.8061.00
343_E353_N0.8041.00
445_R461_F0.8031.00
210_G214_G0.8021.00
71_E75_Y0.8021.00
489_Y530_T0.8011.00
57_R263_L0.8001.00
447_Y451_Q0.7971.00
171_V176_R0.7961.00
44_Y47_Q0.7961.00
215_D228_T0.7941.00
395_Y399_E0.7941.00
486_A500_I0.7931.00
319_E322_V0.7931.00
440_E444_V0.7921.00
317_P345_T0.7911.00
421_G425_R0.7901.00
373_K376_I0.7861.00
74_S179_R0.7801.00
495_T498_C0.7791.00
423_L428_I0.7761.00
389_I420_L0.7751.00
305_L309_K0.7741.00
147_E151_K0.7741.00
56_L59_S0.7731.00
424_L428_I0.7731.00
397_T400_S0.7731.00
409_Q412_Q0.7721.00
317_P347_D0.7721.00
160_N164_T0.7711.00
15_K319_E0.7711.00
388_Q395_Y0.7711.00
373_K378_K0.7701.00
324_A327_S0.7661.00
172_L177_Q0.7651.00
14_I314_I0.7651.00
31_L34_Y0.7611.00
386_Q389_I0.7601.00
150_F191_M0.7591.00
504_A511_V0.7591.00
401_I405_A0.7581.00
219_A225_L0.7561.00
176_R193_L0.7551.00
80_D84_Q0.7541.00
98_Q102_K0.7531.00
258_Y261_S0.7521.00
309_K313_S0.7511.00
439_E443_I0.7511.00
49_Y52_S0.7491.00
15_K19_F0.7491.00
393_F416_M0.7471.00
327_S330_H0.7471.00
452_R500_I0.7461.00
285_I288_M0.7461.00
303_V307_G0.7431.00
253_K258_Y0.7431.00
398_L404_L0.7421.00
424_L427_S0.7421.00
398_L401_I0.7411.00
356_F363_I0.7411.00
378_K382_L0.7401.00
413_I421_G0.7381.00
362_R366_L0.7371.00
479_L483_A0.7341.00
477_L481_P0.7331.00
316_E319_E0.7311.00
172_L197_N0.7291.00
486_A498_C0.7291.00
120_D197_N0.7291.00
146_Q151_K0.7281.00
287_F290_T0.7271.00
390_N397_T0.7271.00
419_S474_I0.7261.00
540_I544_I0.7261.00
407_A411_K0.7241.00
441_A502_I0.7231.00
520_P564_T0.7211.00
328_V359_M0.7201.00
389_I396_N0.7201.00
452_R461_F0.7191.00
174_S177_Q0.7191.00
47_Q51_K0.7171.00
65_D68_K0.7161.00
39_Y43_V0.7131.00
390_N395_Y0.7131.00
289_K293_G0.7111.00
514_T557_H0.7111.00
69_K72_D0.7091.00
425_R428_I0.7081.00
415_K419_S0.7071.00
146_Q150_F0.7071.00
124_V181_Y0.7061.00
394_L413_I0.7051.00
440_E476_K0.7051.00
173_I179_R0.7041.00
388_Q396_N0.7031.00
320_Q324_A0.7021.00
386_Q543_R0.6961.00
420_L425_R0.6961.00
417_V423_L0.6961.00
46_E49_Y0.6961.00
127_A188_G0.6951.00
324_A357_T0.6941.00
409_Q413_I0.6911.00
383_K427_S0.6901.00
417_V427_S0.6901.00
333_I367_M0.6901.00
100_Q103_Q0.6881.00
443_I472_C0.6881.00
484_E488_Q0.6881.00
103_Q106_W0.6841.00
248_Y252_K0.6831.00
418_E421_G0.6831.00
404_L412_Q0.6811.00
271_S275_V0.6801.00
104_E108_Q0.6761.00
198_V205_V0.6751.00
522_M537_L0.6741.00
327_S331_S0.6731.00
46_E50_R0.6721.00
51_K54_E0.6721.00
198_V201_M0.6721.00
321_L352_L0.6711.00
107_D110_A0.6711.00
502_I515_V0.6711.00
175_A196_V0.6711.00
44_Y48_I0.6711.00
438_Q467_D0.6701.00
175_A179_R0.6701.00
440_E443_I0.6691.00
140_D143_Q0.6671.00
402_N411_K0.6671.00
393_F409_Q0.6661.00
304_L308_R0.6651.00
480_Q484_E0.6651.00
444_V448_M0.6641.00
330_H333_I0.6641.00
393_F540_I0.6631.00
47_Q284_K0.6621.00
396_N402_N0.6621.00
482_L540_I0.6621.00
174_S178_I0.6621.00
23_S26_M0.6611.00
62_R65_D0.6611.00
73_V77_I0.6601.00
395_Y414_S0.6591.00
159_R162_W0.6571.00
161_L164_T0.6561.00
407_A410_Q0.6551.00
420_L424_L0.6551.00
42_H46_E0.6541.00
477_L543_R0.6541.00
324_A335_A0.6541.00
465_I468_E0.6531.00
58_M62_R0.6531.00
262_Y273_Y0.6521.00
521_G563_G0.6521.00
170_P174_S0.6511.00
325_M355_H0.6511.00
465_I470_K0.6491.00
466_D506_K0.6491.00
110_A114_S0.6491.00
55_V58_M0.6471.00
385_L395_Y0.6471.00
198_V227_Y0.6471.00
145_E150_F0.6451.00
325_M359_M0.6441.00
84_Q88_S0.6441.00
161_L165_L0.6441.00
202_I206_P0.6431.00
469_V506_K0.6421.00
355_H358_V0.6421.00
167_G172_L0.6421.00
426_N429_H0.6411.00
176_R180_S0.6411.00
197_N200_Q0.6411.00
516_E562_K0.6401.00
421_G428_I0.6401.00
99_Y102_K0.6401.00
283_A287_F0.6391.00
64_E267_Y0.6391.00
123_H195_Q0.6381.00
181_Y189_L0.6371.00
109_L113_A0.6361.00
176_R179_R0.6361.00
402_N418_E0.6361.00
34_Y37_V0.6361.00
316_E320_Q0.6351.00
502_I513_I0.6331.00
446_H449_T0.6331.00
108_Q111_G0.6311.00
383_K390_N0.6311.00
444_V476_K0.6311.00
452_R457_E0.6311.00
265_S268_Q0.6291.00
16_D19_F0.6291.00
122_I194_I0.6250.99
311_A314_I0.6240.99
108_Q112_Y0.6240.99
228_T231_A0.6230.99
45_D278_F0.6230.99
386_Q395_Y0.6220.99
205_V208_D0.6220.99
513_I570_I0.6210.99
51_K55_V0.6210.99
277_P281_M0.6200.99
393_F404_L0.6200.99
105_L113_A0.6190.99
168_S176_R0.6190.99
174_S195_Q0.6190.99
178_I191_M0.6190.99
21_F25_I0.6190.99
294_T298_L0.6180.99
17_K346_Q0.6180.99
395_Y421_G0.6170.99
201_M205_V0.6160.99
393_F480_Q0.6160.99
144_Q149_V0.6150.99
349_A356_F0.6150.99
169_D172_L0.6140.99
369_E372_E0.6140.99
345_T349_A0.6120.99
252_K257_R0.6100.99
452_R459_L0.6080.99
288_M291_V0.6050.99
322_V349_A0.6050.99
393_F539_N0.6040.99
293_G297_L0.6030.99
438_Q465_I0.6020.99
260_I273_Y0.6010.99
353_N360_M0.6000.99
83_I87_L0.6000.99
393_F474_I0.6000.99
41_F44_Y0.5990.99
205_V227_Y0.5990.99
481_P532_G0.5980.99
40_A43_V0.5980.99
82_Q86_I0.5960.99
61_E64_E0.5960.99
72_D75_Y0.5930.99
431_K535_I0.5930.99
383_K388_Q0.5930.99
84_Q87_L0.5920.99
169_D173_I0.5920.99
318_I348_E0.5900.99
121_S125_I0.5900.99
160_N163_M0.5900.99
406_K414_S0.5890.99
336_G360_M0.5890.99
387_A394_L0.5880.99
408_N412_Q0.5880.99
188_G191_M0.5880.99
199_K202_I0.5880.99
119_I194_I0.5880.99
413_I420_L0.5870.99
346_Q349_A0.5870.99
37_V289_K0.5870.99
474_I547_T0.5860.99
123_H126_D0.5860.99
80_D83_I0.5860.99
559_E564_T0.5850.99
220_D226_V0.5850.99
459_L495_T0.5850.99
321_L349_A0.5850.99
67_L70_I0.5840.99
149_V153_A0.5830.99
422_F426_N0.5830.99
423_L427_S0.5820.99
394_L416_M0.5810.99
85_R88_S0.5800.99
343_E350_G0.5800.99
145_E148_E0.5800.99
360_M367_M0.5800.99
382_L395_Y0.5790.99
168_S172_L0.5770.99
321_L353_N0.5750.99
173_I180_S0.5740.99
506_K509_G0.5740.99
367_M373_K0.5730.99
355_H359_M0.5720.99
388_Q393_F0.5710.99
465_I469_V0.5690.99
186_L189_L0.5680.99
52_S55_V0.5680.99
474_I481_P0.5670.99
74_S177_Q0.5660.99
163_M166_G0.5650.99
525_R528_E0.5650.99
172_L180_S0.5650.99
400_S416_M0.5640.99
419_S446_H0.5630.99
100_Q104_E0.5620.99
149_V154_K0.5620.99
399_E412_Q0.5610.99
523_D528_E0.5610.99
322_V325_M0.5590.99
538_W541_R0.5590.99
347_D353_N0.5580.99
255_G258_Y0.5560.99
128_R132_Y0.5560.99
386_Q489_Y0.5550.99
401_I404_L0.5550.99
178_I193_L0.5550.99
160_N165_L0.5540.99
337_V353_N0.5540.99
147_E150_F0.5530.99
132_Y135_G0.5520.99
387_A399_E0.5520.99
394_L424_L0.5510.99
177_Q181_Y0.5500.99
332_G336_G0.5500.99
359_M370_N0.5500.99
258_Y262_Y0.5490.99
248_Y251_I0.5490.99
162_W166_G0.5490.99
402_N413_I0.5480.99
81_E84_Q0.5470.99
304_L307_G0.5470.99
397_T481_P0.5450.99
130_S133_S0.5450.99
383_K387_A0.5450.99
131_E136_S0.5440.99
359_M366_L0.5420.99
511_V570_I0.5420.99
73_V119_I0.5410.99
459_L463_L0.5410.99
404_L413_I0.5390.99
404_L410_Q0.5380.99
123_H131_E0.5380.99
167_G174_S0.5380.99
395_Y398_L0.5380.99
168_S171_V0.5370.98
452_R460_K0.5370.98
444_V480_Q0.5370.98
561_E564_T0.5370.98
386_Q399_E0.5370.98
337_V357_T0.5370.98
313_S317_P0.5360.98
500_I515_V0.5360.98
81_E85_R0.5360.98
59_S63_I0.5350.98
117_K120_D0.5350.98
481_P540_I0.5340.98
423_L431_K0.5330.98
30_F296_F0.5330.98
16_D20_V0.5310.98
28_V31_L0.5310.98
59_S62_R0.5300.98
217_M228_T0.5300.98
48_I51_K0.5300.98
342_P357_T0.5290.98
397_T417_V0.5290.98
411_K414_S0.5290.98
484_E489_Y0.5290.98
290_T293_G0.5290.98
386_Q393_F0.5280.98
59_S67_L0.5270.98
538_W543_R0.5270.98
506_K511_V0.5260.98
389_I424_L0.5260.98
480_Q540_I0.5250.98
394_L417_V0.5250.98
359_M367_M0.5250.98
424_L535_I0.5250.98
221_Q271_S0.5240.98
324_A356_F0.5240.98
395_Y404_L0.5220.98
350_G357_T0.5220.98
333_I336_G0.5220.98
372_E375_L0.5220.98
88_S189_L0.5210.98
171_V175_A0.5200.98
134_A137_S0.5190.98
516_E563_G0.5190.98
159_R163_M0.5190.98
379_E382_L0.5190.98
475_P570_I0.5190.98
423_L542_E0.5180.98
43_V46_E0.5180.98
512_C555_R0.5180.98
461_F500_I0.5170.98
383_K386_Q0.5160.98
397_T450_I0.5160.98
331_S359_M0.5150.98
416_M421_G0.5140.98
474_I489_Y0.5140.98
447_Y476_K0.5130.98
441_A445_R0.5130.98
428_I431_K0.5110.98
343_E347_D0.5110.98
52_S59_S0.5110.98
216_I220_D0.5110.98
347_D351_M0.5100.98
395_Y400_S0.5090.98
299_F303_V0.5090.98
298_L305_L0.5080.98
60_S272_Y0.5070.98
40_A288_M0.5070.98
393_F399_E0.5070.98
39_Y291_V0.5060.98
287_F291_V0.5040.98
264_Q269_N0.5040.98
549_G571_P0.5030.98
70_I194_I0.5030.98
448_M484_E0.5030.98
384_A388_Q0.5020.98
342_P345_T0.5010.98
398_L417_V0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i5sA 2 0.4315 100 0.546 Contact Map
4bixA 2 0.3449 100 0.585 Contact Map
4ctiA 2 0.3709 100 0.606 Contact Map
3a0rA 2 0.5234 100 0.657 Contact Map
4gczA 2 0.5754 100 0.664 Contact Map
4q20A 2 0.3432 100 0.67 Contact Map
3d36A 2 0.3293 100 0.67 Contact Map
4r39A 1 0.3293 100 0.672 Contact Map
2c2aA 2 0.3501 100 0.676 Contact Map
2q8gA 2 0.4714 100 0.679 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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