RLMCD - BACSU - GREMLIN Contacts

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RLMCD - 23S rRNA (uracil-C(5))-methyltransferase RlmCD

UniProt:	O31503	Sequences: MKMKPPVEKNEYYDVTFEDLTHEGAGVAKVQGFPIFVPNALPEEKAQIKVTRVKKGFAFGRLIELKEESPHRTDAPCPIYKQCGGCQLQHMTYEGQLLFKQKQVKDVLERIGKLDLSKVTVHPTLGMEDPWNYRNKAQVPVGEREGGLVAGFYQQRSHDIIDMSACLIQQSKNDEAVQAVKDICANYGVKAYNEERHKGWLRHIMVRYGVVTGEMMIVFITRTSDFPHKAKIIEDITAQFPHVKSIVQNINPNKTNVIFGNETNVIWGEEYIYDLIGDVKFAISARSFYQVNPEQTKVLYDKALEYAELQGEETVIDAYCGIGTISLFLAKQAKKVYGVEIVPEAIEDAKRNAELNGNTNAEFAVGEAETVIPKWYEEGITADTLVVDPPRKGCDEALLRTIVEMKPKRVVYVSCNPGTLARDLRVLEDGGYVTREVQPVDMFPHTNHVECCVLIKLKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	459 (439)
Sequences:	4480 (3317)
Seq/√Len:	158.3

ECOLI - RLMD RLMC TRMA
BACSU - RLMCD YFJO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
47_Q	64_E	4.258	1.00
424_L	455_I	3.401	1.00
435_R	456_K	3.347	1.00
95_G	98_L	3.297	1.00
101_Q	105_K	3.071	1.00
335_K	362_E	3.031	1.00
122_H	436_E	2.946	1.00
302_K	305_E	2.901	1.00
71_H	95_G	2.885	1.00
221_T	248_Q	2.862	1.00
329_L	386_V	2.853	1.00
45_K	67_E	2.829	1.00
16_T	45_K	2.815	1.00
385_L	402_I	2.594	1.00
48_I	60_G	2.593	1.00
15_V	48_I	2.534	1.00
96_Q	445_H	2.510	1.00
62_L	65_L	2.461	1.00
425_R	429_D	2.409	1.00
170_Q	208_Y	2.399	1.00
162_D	181_K	2.386	1.00
402_I	410_V	2.386	1.00
275_L	280_K	2.369	1.00
273_Y	280_K	2.357	1.00
154_Q	159_D	2.306	1.00
77_C	83_C	2.301	1.00
15_V	28_A	2.269	1.00
275_L	278_D	2.258	1.00
102_K	106_D	2.251	1.00
434_T	453_V	2.187	1.00
314_T	335_K	2.177	1.00
306_Y	436_E	2.161	1.00
101_Q	123_P	2.157	1.00
41_L	44_E	2.127	1.00
49_K	61_R	2.100	1.00
303_A	413_V	2.098	1.00
320_C	338_G	2.054	1.00
83_C	86_C	2.052	1.00
366_G	371_V	2.045	1.00
265_V	270_E	2.040	1.00
77_C	86_C	2.037	1.00
101_Q	124_T	2.013	1.00
282_A	351_R	1.979	1.00
40_A	46_A	1.978	1.00
65_L	68_E	1.978	1.00
387_V	394_C	1.964	1.00
17_F	37_V	1.924	1.00
20_L	42_P	1.869	1.00
403_V	430_G	1.869	1.00
52_R	59_F	1.834	1.00
316_I	382_A	1.829	1.00
320_C	346_I	1.820	1.00
17_F	40_A	1.800	1.00
17_F	28_A	1.799	1.00
340_E	346_I	1.798	1.00
47_Q	66_K	1.784	1.00
367_E	370_T	1.783	1.00
83_C	166_C	1.781	1.00
299_L	440_V	1.779	1.00
284_S	348_D	1.779	1.00
280_K	355_L	1.738	1.00
147_G	185_A	1.728	1.00
399_L	427_L	1.727	1.00
399_L	426_V	1.722	1.00
93_Y	97_L	1.718	1.00
77_C	166_C	1.714	1.00
141_V	204_I	1.703	1.00
271_Y	282_A	1.694	1.00
216_M	245_S	1.679	1.00
17_F	46_A	1.674	1.00
18_E	29_K	1.674	1.00
46_A	65_L	1.672	1.00
301_D	305_E	1.668	1.00
351_R	354_E	1.667	1.00
76_P	131_W	1.658	1.00
383_D	408_K	1.658	1.00
132_N	171_S	1.649	1.00
245_S	270_E	1.642	1.00
396_E	400_R	1.630	1.00
420_L	451_C	1.630	1.00
176_A	215_M	1.612	1.00
71_H	92_T	1.609	1.00
209_G	212_T	1.600	1.00
86_C	166_C	1.557	1.00
394_C	399_L	1.557	1.00
420_L	424_L	1.550	1.00
358_N	361_A	1.547	1.00
113_K	425_R	1.545	1.00
420_L	453_V	1.537	1.00
35_I	58_A	1.530	1.00
304_L	332_Q	1.519	1.00
49_K	63_I	1.511	1.00
33_F	58_A	1.510	1.00
97_L	126_G	1.507	1.00
172_K	208_Y	1.504	1.00
343_P	347_E	1.503	1.00
338_G	349_A	1.494	1.00
125_L	440_V	1.492	1.00
186_N	235_D	1.489	1.00
279_V	327_L	1.472	1.00
247_V	265_V	1.472	1.00
21_T	25_A	1.472	1.00
403_V	431_G	1.468	1.00
171_S	175_E	1.451	1.00
315_V	333_A	1.437	1.00
98_L	101_Q	1.434	1.00
92_T	95_G	1.427	1.00
326_S	336_V	1.425	1.00
297_K	301_D	1.419	1.00
122_H	438_Q	1.417	1.00
142_G	160_I	1.408	1.00
302_K	438_Q	1.406	1.00
125_L	298_V	1.403	1.00
104_V	439_P	1.391	1.00
40_A	62_L	1.389	1.00
19_D	102_K	1.385	1.00
235_D	239_Q	1.381	1.00
173_N	206_V	1.380	1.00
104_V	449_V	1.373	1.00
279_V	331_K	1.370	1.00
313_E	383_D	1.368	1.00
385_L	407_P	1.362	1.00
309_L	315_V	1.358	1.00
21_T	27_V	1.355	1.00
109_E	115_D	1.353	1.00
76_P	167_L	1.352	1.00
197_H	254_K	1.346	1.00
347_E	350_K	1.345	1.00
28_A	48_I	1.342	1.00
244_K	269_E	1.341	1.00
307_A	384_T	1.332	1.00
214_E	269_E	1.331	1.00
50_V	58_A	1.329	1.00
310_Q	313_E	1.323	1.00
28_A	37_V	1.321	1.00
108_L	424_L	1.320	1.00
128_E	298_V	1.318	1.00
237_T	267_W	1.318	1.00
108_L	437_V	1.303	1.00
277_G	328_F	1.297	1.00
179_A	240_F	1.294	1.00
226_F	229_K	1.291	1.00
35_I	50_V	1.291	1.00
79_I	163_M	1.290	1.00
309_L	313_E	1.280	1.00
91_M	95_G	1.273	1.00
205_M	218_V	1.272	1.00
29_K	34_P	1.265	1.00
33_F	53_V	1.263	1.00
184_C	201_L	1.260	1.00
175_E	242_H	1.256	1.00
16_T	67_E	1.254	1.00
327_L	361_A	1.251	1.00
15_V	30_V	1.247	1.00
51_T	61_R	1.243	1.00
273_Y	282_A	1.243	1.00
214_E	244_K	1.239	1.00
236_I	243_V	1.238	1.00
338_G	363_F	1.237	1.00
127_M	130_P	1.229	1.00
121_V	124_T	1.227	1.00
302_K	306_Y	1.221	1.00
234_E	238_A	1.209	1.00
184_C	191_A	1.195	1.00
143_E	147_G	1.191	1.00
19_D	106_D	1.186	1.00
312_E	334_K	1.185	1.00
133_Y	446_T	1.185	1.00
165_A	174_D	1.184	1.00
135_N	293_P	1.182	1.00
451_C	455_I	1.182	1.00
349_A	363_F	1.174	1.00
234_E	237_T	1.174	1.00
435_R	454_L	1.170	1.00
73_T	92_T	1.167	1.00
41_L	90_H	1.167	1.00
179_A	239_Q	1.163	1.00
400_R	404_E	1.157	1.00
158_H	194_E	1.155	1.00
306_Y	454_L	1.152	1.00
132_N	167_L	1.152	1.00
50_V	60_G	1.149	1.00
176_A	240_F	1.145	1.00
141_V	150_A	1.143	1.00
15_V	37_V	1.139	1.00
424_L	434_T	1.137	1.00
247_V	285_A	1.134	1.00
279_V	358_N	1.131	1.00
41_L	91_M	1.127	1.00
19_D	29_K	1.126	1.00
137_A	169_Q	1.126	1.00
263_T	286_R	1.125	1.00
45_K	66_K	1.125	1.00
409_R	456_K	1.124	1.00
25_A	59_F	1.120	1.00
314_T	337_Y	1.117	1.00
200_W	223_T	1.107	1.00
98_L	102_K	1.100	1.00
102_K	105_K	1.091	0.99
338_G	361_A	1.088	0.99
309_L	333_A	1.085	0.99
77_C	85_G	1.078	0.99
232_I	235_D	1.078	0.99
140_P	160_I	1.075	0.99
200_W	222_R	1.068	0.99
15_V	35_I	1.067	0.99
410_V	432_Y	1.067	0.99
172_K	175_E	1.064	0.99
53_V	58_A	1.058	0.99
343_P	365_V	1.055	0.99
282_A	355_L	1.054	0.99
75_A	89_Q	1.048	0.99
318_A	398_L	1.045	0.99
224_S	262_E	1.039	0.99
293_P	296_T	1.039	0.99
108_L	420_L	1.033	0.99
330_A	358_N	1.031	0.99
298_V	440_V	1.030	0.99
287_S	348_D	1.027	0.99
132_N	165_A	1.026	0.99
433_V	456_K	1.023	0.99
121_V	439_P	1.023	0.99
19_D	27_V	1.019	0.99
327_L	353_A	1.018	0.99
83_C	89_Q	1.016	0.99
105_K	109_E	1.015	0.99
125_L	438_Q	1.014	0.99
277_G	301_D	1.013	0.99
436_E	454_L	1.012	0.99
278_D	331_K	1.011	0.99
374_K	378_E	1.011	0.99
320_C	363_F	1.011	0.99
416_N	419_T	1.010	0.99
214_E	273_Y	1.010	0.99
309_L	384_T	1.008	0.99
212_T	275_L	1.007	0.99
333_A	360_N	1.004	0.99
350_K	362_E	1.001	0.99
164_S	178_Q	0.999	0.99
287_S	345_A	0.995	0.99
148_L	185_A	0.995	0.99
211_V	275_L	0.991	0.99
273_Y	355_L	0.991	0.99
396_E	426_V	0.991	0.99
129_D	294_E	0.991	0.99
107_V	417_P	0.990	0.99
148_L	184_C	0.986	0.99
233_I	237_T	0.982	0.99
400_R	426_V	0.980	0.99
302_K	452_C	0.975	0.99
302_K	436_E	0.974	0.99
80_Y	90_H	0.973	0.99
353_A	363_F	0.971	0.99
148_L	191_A	0.969	0.99
303_A	411_V	0.969	0.99
339_V	371_V	0.968	0.99
91_M	99_F	0.967	0.99
87_Q	447_N	0.961	0.99
452_C	456_K	0.959	0.99
382_A	385_L	0.955	0.99
406_K	457_L	0.955	0.99
326_S	361_A	0.954	0.99
26_G	40_A	0.953	0.99
218_V	285_A	0.950	0.99
277_G	297_K	0.948	0.99
193_N	196_R	0.942	0.98
263_T	285_A	0.940	0.98
77_C	80_Y	0.934	0.98
352_N	356_N	0.928	0.98
410_V	427_L	0.927	0.98
15_V	46_A	0.926	0.98
453_V	456_K	0.926	0.98
298_V	301_D	0.925	0.98
337_Y	364_A	0.925	0.98
217_I	243_V	0.924	0.98
97_L	124_T	0.923	0.98
407_P	432_Y	0.921	0.98
253_N	261_N	0.915	0.98
320_C	349_A	0.912	0.98
308_E	409_R	0.907	0.98
351_R	355_L	0.907	0.98
82_Q	154_Q	0.906	0.98
250_I	264_N	0.905	0.98
249_N	260_G	0.904	0.98
172_K	242_H	0.899	0.98
130_P	445_H	0.898	0.98
122_H	306_Y	0.897	0.98
303_A	386_V	0.894	0.98
426_V	429_D	0.891	0.98
88_L	99_F	0.891	0.98
77_C	89_Q	0.886	0.98
426_V	430_G	0.886	0.98
176_A	179_A	0.885	0.98
306_Y	438_Q	0.885	0.98
38_P	155_Q	0.885	0.98
172_K	215_M	0.884	0.98
230_A	234_E	0.882	0.98
182_D	185_A	0.879	0.98
347_E	351_R	0.876	0.98
302_K	440_V	0.876	0.98
105_K	121_V	0.875	0.98
222_R	252_P	0.875	0.98
346_I	365_V	0.871	0.97
319_Y	369_E	0.871	0.97
315_V	384_T	0.866	0.97
101_Q	121_V	0.860	0.97
315_V	329_L	0.860	0.97
424_L	453_V	0.860	0.97
279_V	330_A	0.856	0.97
124_T	127_M	0.852	0.97
235_D	238_A	0.851	0.97
330_A	336_V	0.850	0.97
182_D	239_Q	0.849	0.97
17_F	26_G	0.845	0.97
317_D	338_G	0.839	0.97
314_T	334_K	0.839	0.97
236_I	240_F	0.830	0.97
434_T	455_I	0.829	0.97
131_W	445_H	0.826	0.96
86_C	89_Q	0.823	0.96
112_G	421_A	0.822	0.96
75_A	166_C	0.821	0.96
354_E	359_T	0.817	0.96
187_Y	235_D	0.816	0.96
437_V	453_V	0.815	0.96
77_C	84_G	0.815	0.96
344_E	347_E	0.813	0.96
137_A	152_F	0.813	0.96
350_K	354_E	0.811	0.96
295_Q	442_M	0.809	0.96
78_P	165_A	0.809	0.96
337_Y	382_A	0.808	0.96
75_A	80_Y	0.808	0.96
408_K	456_K	0.806	0.96
150_A	181_K	0.805	0.96
291_V	442_M	0.803	0.96
376_Y	405_M	0.803	0.96
368_A	372_I	0.801	0.96
140_P	153_Y	0.798	0.96
300_Y	325_I	0.796	0.96
247_V	263_T	0.792	0.96
229_K	264_N	0.789	0.95
125_L	302_K	0.788	0.95
232_I	236_I	0.784	0.95
295_Q	298_V	0.783	0.95
44_E	72_R	0.783	0.95
129_D	132_N	0.779	0.95
408_K	432_Y	0.778	0.95
180_V	204_I	0.777	0.95
100_K	441_D	0.773	0.95
201_L	219_F	0.770	0.95
137_A	173_N	0.769	0.95
304_L	329_L	0.769	0.95
44_E	69_S	0.769	0.95
316_I	372_I	0.769	0.95
141_V	184_C	0.769	0.95
291_V	420_L	0.767	0.95
37_V	48_I	0.766	0.95
283_I	289_Y	0.765	0.95
183_I	232_I	0.764	0.95
50_V	53_V	0.764	0.95
85_G	166_C	0.763	0.95
314_T	380_I	0.763	0.95
132_N	174_D	0.761	0.94
406_K	431_G	0.760	0.94
182_D	186_N	0.758	0.94
71_H	98_L	0.757	0.94
288_F	415_C	0.756	0.94
409_R	454_L	0.754	0.94
371_V	374_K	0.753	0.94
434_T	437_V	0.752	0.94
274_D	289_Y	0.750	0.94
123_P	439_P	0.749	0.94
80_Y	87_Q	0.749	0.94
143_E	146_G	0.747	0.94
411_V	452_C	0.741	0.94
80_Y	83_C	0.740	0.94
304_L	328_F	0.740	0.94
231_K	235_D	0.740	0.94
93_Y	130_P	0.737	0.93
326_S	363_F	0.737	0.93
369_E	395_D	0.736	0.93
246_I	267_W	0.735	0.93
27_V	34_P	0.735	0.93
269_E	273_Y	0.735	0.93
89_Q	131_W	0.733	0.93
415_C	450_E	0.733	0.93
299_L	442_M	0.732	0.93
183_I	187_Y	0.729	0.93
120_T	436_E	0.729	0.93
296_T	324_T	0.729	0.93
176_A	243_V	0.729	0.93
44_E	90_H	0.729	0.93
135_N	289_Y	0.727	0.93
192_Y	199_G	0.726	0.93
272_I	276_I	0.726	0.93
114_L	428_E	0.725	0.93
75_A	83_C	0.722	0.93
320_C	340_E	0.718	0.93
249_N	263_T	0.715	0.92
307_A	411_V	0.714	0.92
313_E	333_A	0.714	0.92
341_I	367_E	0.712	0.92
451_C	456_K	0.712	0.92
169_Q	173_N	0.709	0.92
364_A	371_V	0.705	0.92
93_Y	126_G	0.704	0.92
403_V	427_L	0.704	0.92
104_V	451_C	0.702	0.92
219_F	222_R	0.702	0.92
96_Q	441_D	0.700	0.92
337_Y	362_E	0.700	0.92
306_Y	452_C	0.697	0.91
387_V	402_I	0.696	0.91
108_L	421_A	0.694	0.91
304_L	326_S	0.689	0.91
231_K	234_E	0.688	0.91
428_E	433_V	0.687	0.91
47_Q	63_I	0.684	0.91
451_C	454_L	0.683	0.91
190_K	200_W	0.683	0.91
170_Q	174_D	0.682	0.91
30_V	48_I	0.681	0.90
346_I	350_K	0.680	0.90
54_K	57_F	0.680	0.90
107_V	421_A	0.679	0.90
211_V	297_K	0.678	0.90
412_Y	420_L	0.677	0.90
403_V	426_V	0.677	0.90
46_A	62_L	0.674	0.90
337_Y	380_I	0.671	0.90
335_K	380_I	0.669	0.90
141_V	201_L	0.669	0.90
28_A	46_A	0.667	0.90
343_P	350_K	0.666	0.89
169_Q	174_D	0.664	0.89
205_M	220_I	0.664	0.89
127_M	292_N	0.661	0.89
223_T	252_P	0.661	0.89
25_A	38_P	0.660	0.89
194_E	256_N	0.658	0.89
346_I	363_F	0.658	0.89
245_S	268_G	0.657	0.89
233_I	246_I	0.655	0.89
327_L	358_N	0.654	0.89
127_M	294_E	0.652	0.88
124_T	439_P	0.649	0.88
276_I	296_T	0.649	0.88
93_Y	441_D	0.649	0.88
40_A	44_E	0.648	0.88
80_Y	86_C	0.647	0.88
17_F	65_L	0.647	0.88
370_T	397_A	0.644	0.88
312_E	333_A	0.644	0.88
179_A	182_D	0.643	0.88
111_I	114_L	0.643	0.88
341_I	346_I	0.642	0.88
366_G	373_P	0.641	0.88
153_Y	158_H	0.639	0.87
369_E	397_A	0.639	0.87
428_E	434_T	0.639	0.87
107_V	111_I	0.638	0.87
299_L	452_C	0.637	0.87
290_Q	415_C	0.637	0.87
20_L	99_F	0.636	0.87
216_M	219_F	0.635	0.87
315_V	336_V	0.635	0.87
143_E	191_A	0.635	0.87
376_Y	401_T	0.634	0.87
449_V	454_L	0.634	0.87
36_F	57_F	0.634	0.87
295_Q	440_V	0.632	0.87
331_K	358_N	0.632	0.87
240_F	243_V	0.631	0.87
39_N	62_L	0.630	0.87
178_Q	182_D	0.629	0.87
170_Q	173_N	0.628	0.87
298_V	302_K	0.625	0.86
387_V	412_Y	0.622	0.86
219_F	223_T	0.621	0.86
205_M	259_F	0.621	0.86
449_V	455_I	0.620	0.86
63_I	67_E	0.620	0.86
251_N	255_T	0.618	0.86
367_E	371_V	0.617	0.86
415_C	443_F	0.617	0.86
75_A	86_C	0.617	0.86
140_P	203_H	0.615	0.85
413_V	452_C	0.615	0.85
187_Y	228_H	0.615	0.85
110_R	114_L	0.612	0.85
67_E	70_P	0.612	0.85
54_K	58_A	0.608	0.85
281_F	324_T	0.607	0.85
181_K	185_A	0.607	0.85
440_V	452_C	0.607	0.85
153_Y	157_S	0.606	0.85
123_P	438_Q	0.604	0.84
243_V	246_I	0.604	0.84
228_H	231_K	0.604	0.84
244_K	272_I	0.604	0.84
139_V	150_A	0.603	0.84
51_T	59_F	0.603	0.84
144_R	149_V	0.603	0.84
33_F	57_F	0.602	0.84
114_L	434_T	0.601	0.84
35_I	48_I	0.600	0.84
304_L	331_K	0.598	0.84
233_I	236_I	0.597	0.84
443_F	450_E	0.596	0.84
54_K	59_F	0.595	0.84
111_I	421_A	0.595	0.84
208_Y	215_M	0.594	0.83
370_T	373_P	0.594	0.83
248_Q	266_I	0.593	0.83
101_Q	438_Q	0.591	0.83
164_S	181_K	0.591	0.83
322_I	326_S	0.590	0.83
114_L	424_L	0.590	0.83
154_Q	161_I	0.589	0.83
142_G	149_V	0.589	0.83
236_I	239_Q	0.588	0.83
288_F	450_E	0.588	0.83
139_V	177_V	0.587	0.83
286_R	344_E	0.586	0.83
38_P	62_L	0.586	0.83
30_V	50_V	0.585	0.82
233_I	267_W	0.585	0.82
327_L	363_F	0.584	0.82
206_V	217_I	0.584	0.82
27_V	36_F	0.584	0.82
247_V	270_E	0.584	0.82
30_V	33_F	0.584	0.82
395_D	399_L	0.583	0.82
199_G	202_R	0.582	0.82
69_S	72_R	0.582	0.82
313_E	408_K	0.581	0.82
339_V	368_A	0.581	0.82
84_G	166_C	0.580	0.82
386_V	413_V	0.580	0.82
40_A	65_L	0.580	0.82
245_S	265_V	0.579	0.82
209_G	272_I	0.579	0.82
349_A	361_A	0.578	0.82
237_T	240_F	0.578	0.82
276_I	297_K	0.577	0.82
366_G	370_T	0.576	0.82
21_T	34_P	0.576	0.82
289_Y	322_I	0.574	0.81
133_Y	291_V	0.571	0.81
208_Y	213_G	0.571	0.81
80_Y	89_Q	0.571	0.81
272_I	275_L	0.570	0.81
139_V	173_N	0.570	0.81
39_N	65_L	0.568	0.81
48_I	62_L	0.567	0.80
250_I	262_E	0.567	0.80
173_N	208_Y	0.566	0.80
95_G	99_F	0.563	0.80
340_E	345_A	0.563	0.80
218_V	249_N	0.562	0.80
35_I	51_T	0.562	0.80
229_K	233_I	0.561	0.80
277_G	304_L	0.560	0.80
77_C	87_Q	0.559	0.80
176_A	206_V	0.559	0.80
306_Y	411_V	0.558	0.79
84_G	161_I	0.558	0.79
372_I	398_L	0.558	0.79
20_L	41_L	0.558	0.79
139_V	318_A	0.557	0.79
93_Y	127_M	0.556	0.79
127_M	295_Q	0.556	0.79
202_R	207_R	0.556	0.79
307_A	409_R	0.555	0.79
322_I	325_I	0.555	0.79
88_L	91_M	0.553	0.79
366_G	372_I	0.553	0.79
136_K	300_Y	0.553	0.79
133_Y	445_H	0.552	0.79
89_Q	166_C	0.550	0.78
338_G	346_I	0.550	0.78
190_K	198_K	0.549	0.78
76_P	445_H	0.548	0.78
180_V	219_F	0.548	0.78
417_P	449_V	0.548	0.78
288_F	443_F	0.547	0.78
279_V	322_I	0.547	0.78
299_L	413_V	0.546	0.78
41_L	69_S	0.545	0.78
184_C	189_V	0.544	0.78
78_P	167_L	0.542	0.77
212_T	274_D	0.539	0.77
445_H	448_H	0.538	0.77
79_I	166_C	0.538	0.77
368_A	398_L	0.537	0.77
68_E	74_D	0.536	0.77
200_W	221_T	0.536	0.77
37_V	46_A	0.536	0.77
391_R	448_H	0.536	0.77
22_H	107_V	0.535	0.77
325_I	386_V	0.535	0.77
288_F	389_P	0.534	0.76
137_A	177_V	0.534	0.76
370_T	374_K	0.533	0.76
229_K	248_Q	0.531	0.76
220_I	225_D	0.529	0.76
300_Y	328_F	0.528	0.76
411_V	454_L	0.528	0.76
304_L	315_V	0.528	0.76
108_L	434_T	0.527	0.76
216_M	220_I	0.527	0.76
212_T	272_I	0.525	0.75
202_R	251_N	0.524	0.75
389_P	415_C	0.524	0.75
189_V	200_W	0.523	0.75
219_F	246_I	0.523	0.75
414_S	419_T	0.523	0.75
51_T	62_L	0.523	0.75
274_D	322_I	0.522	0.75
149_V	162_D	0.522	0.75
384_T	411_V	0.520	0.75
296_T	300_Y	0.520	0.75
364_A	375_W	0.517	0.74
83_C	87_Q	0.516	0.74
305_E	436_E	0.515	0.74
143_E	148_L	0.515	0.74
18_E	28_A	0.514	0.74
79_I	167_L	0.514	0.74
325_I	328_F	0.513	0.74
289_Y	324_T	0.512	0.73
249_N	259_F	0.512	0.73
38_P	51_T	0.511	0.73
139_V	163_M	0.511	0.73
180_V	184_C	0.510	0.73
313_E	384_T	0.509	0.73
128_E	294_E	0.509	0.73
400_R	430_G	0.508	0.73
106_D	109_E	0.508	0.73
428_E	431_G	0.508	0.73
111_I	422_R	0.508	0.73
276_I	289_Y	0.508	0.73
154_Q	157_S	0.508	0.73
356_N	360_N	0.508	0.73
65_L	72_R	0.507	0.73
29_K	32_G	0.507	0.73
73_T	130_P	0.507	0.73
369_E	373_P	0.506	0.73
183_I	236_I	0.506	0.73
180_V	232_I	0.505	0.72
308_E	332_Q	0.505	0.72
361_A	365_V	0.504	0.72
37_V	40_A	0.504	0.72
347_E	365_V	0.503	0.72
237_T	243_V	0.503	0.72
79_I	83_C	0.502	0.72
300_Y	324_T	0.502	0.72
372_I	401_T	0.500	0.72

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jjqA	1	0.8497	100	0.242	Contact Map
1uwvA	1	0.9041	100	0.252	Contact Map
3bt7A	1	0.7669	100	0.448	Contact Map
3vseA	1	0.7342	100	0.687	Contact Map
4dmgA	2	0.719	100	0.707	Contact Map
2b78A	1	0.7233	100	0.714	Contact Map
1wxxA	2	0.7211	100	0.72	Contact Map
3c0kA	2	0.7298	100	0.726	Contact Map
2as0A	2	0.7364	100	0.754	Contact Map
3a27A	1	0.4423	100	0.764	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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