GREMLIN Database
SWRC - Swarming motility protein SwrC
UniProt: O31501 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 1052 (994)
Sequences: 15821 (10172)
Seq/√Len: 322.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
968_S971_E4.1231.00
237_K240_K4.0561.00
336_E339_K3.9661.00
65_T90_S3.9281.00
338_K341_K3.9141.00
240_K291_S3.8251.00
50_T90_S3.7351.00
739_V817_K3.6621.00
925_G1019_G3.5191.00
551_V1030_L3.4441.00
612_A646_A3.4351.00
331_D360_T3.2501.00
148_N151_E3.1631.00
6_N10_K3.0851.00
607_E610_N3.0701.00
553_N974_L3.0671.00
241_N291_S3.0511.00
451_E454_R2.9971.00
78_V94_I2.9221.00
142_V156_V2.9101.00
187_F202_V2.8971.00
769_T780_V2.8641.00
741_D815_K2.8461.00
704_D707_D2.8131.00
701_S704_D2.8071.00
65_T85_S2.7961.00
307_R616_E2.7941.00
167_I332_D2.7661.00
740_A745_L2.7551.00
745_L755_I2.7411.00
163_K336_E2.7321.00
61_A832_V2.7121.00
192_L197_L2.6761.00
450_D461_E2.6741.00
240_K296_I2.6411.00
334_K354_D2.6101.00
309_N627_T2.6011.00
715_I858_K2.5561.00
371_I375_I2.5481.00
907_A960_I2.5431.00
751_T754_Q2.5411.00
236_I240_K2.5411.00
79_S95_E2.5321.00
290_L296_I2.5241.00
715_I718_D2.5071.00
152_L347_F2.4711.00
404_I508_A2.4391.00
609_E613_E2.4351.00
341_K348_N2.4131.00
244_I293_I2.4111.00
188_K191_K2.3991.00
549_K978_S2.3471.00
708_T865_V2.3311.00
79_S97_D2.3241.00
713_E717_K2.3151.00
707_D711_D2.2881.00
741_D744_K2.2881.00
662_E665_N2.2831.00
155_Q347_F2.2801.00
967_L975_E2.2671.00
408_V504_F2.2361.00
716_M852_I2.2341.00
929_S1015_V2.2311.00
328_E332_D2.2271.00
185_F206_I2.2161.00
697_V712_I2.2111.00
661_K669_E2.1791.00
793_K796_E2.1561.00
844_N847_A2.1431.00
203_K782_I2.1391.00
187_F199_E2.1331.00
963_E1036_Y2.1221.00
962_K965_E2.1191.00
843_D851_A2.1041.00
186_S297_K2.1001.00
595_L650_I2.0971.00
239_L290_L2.0961.00
181_E298_D2.0921.00
739_V815_K2.0711.00
445_R465_E2.0581.00
740_A755_I2.0531.00
557_S970_R2.0531.00
145_D311_K2.0431.00
973_L1037_E2.0401.00
368_S372_F2.0221.00
624_H661_K2.0171.00
712_I856_I2.0151.00
962_K967_L2.0141.00
713_E727_S1.9891.00
809_K812_D1.9861.00
737_T819_G1.9801.00
999_A1018_I1.9801.00
719_E851_A1.9751.00
68_V72_V1.9561.00
145_D348_N1.9561.00
738_F814_A1.9431.00
654_S657_P1.9421.00
599_P603_E1.9411.00
796_E811_G1.9371.00
621_D673_Q1.9351.00
543_R546_N1.9281.00
445_R450_D1.9271.00
626_D653_E1.9171.00
722_L725_V1.9101.00
724_N839_E1.9031.00
750_L800_I1.9021.00
235_T238_D1.8951.00
68_V92_V1.8901.00
58_S62_D1.8841.00
710_K713_E1.8721.00
693_L838_G1.8641.00
444_R448_L1.8581.00
548_Y977_G1.8511.00
144_S147_D1.8481.00
307_R609_E1.8471.00
568_L572_G1.8461.00
60_V64_V1.8461.00
554_W558_H1.8461.00
13_F899_V1.8421.00
441_N465_E1.8311.00
332_D335_A1.8301.00
237_K241_N1.8141.00
478_I507_A1.8111.00
397_S512_I1.7911.00
543_R547_I1.7861.00
962_K975_E1.7811.00
853_Q877_A1.7781.00
791_S794_D1.7751.00
160_L340_F1.7741.00
189_E788_E1.7731.00
722_L848_V1.7721.00
192_L293_I1.7611.00
622_R669_E1.7611.00
559_K1037_E1.7581.00
970_R1037_E1.7571.00
713_E725_V1.7461.00
182_E781_N1.7441.00
614_K617_K1.7391.00
72_V94_I1.7381.00
295_T785_E1.7331.00
27_L31_M1.7291.00
708_T711_D1.7281.00
11_N903_G1.7181.00
203_K207_Q1.7181.00
709_V834_A1.7171.00
744_K747_K1.7051.00
32_N410_Q1.6961.00
669_E673_Q1.6951.00
853_Q857_D1.6941.00
549_K553_N1.6921.00
619_L670_I1.6871.00
593_M650_I1.6851.00
612_A630_Y1.6811.00
234_E238_D1.6771.00
94_I109_A1.6721.00
750_L813_V1.6711.00
558_H561_I1.6681.00
65_T83_S1.6651.00
931_E1015_V1.6631.00
668_K672_K1.6581.00
6_N460_R1.6561.00
143_S350_S1.6541.00
654_S658_D1.6461.00
563_S567_V1.6421.00
72_V92_V1.6421.00
617_K621_D1.6381.00
851_A854_K1.6361.00
210_D769_T1.6331.00
414_I500_L1.6261.00
331_D335_A1.6201.00
613_E617_K1.6201.00
328_E331_D1.6161.00
198_D201_T1.6161.00
364_D368_S1.6111.00
23_T403_L1.6071.00
554_W557_S1.6061.00
68_V116_V1.6031.00
574_L578_P1.6031.00
737_T817_K1.6011.00
197_L201_T1.5981.00
334_K351_A1.5911.00
671_Q724_N1.5891.00
618_I673_Q1.5891.00
850_A853_Q1.5801.00
441_N444_R1.5771.00
785_E788_E1.5741.00
582_A846_T1.5721.00
706_K710_K1.5721.00
622_R673_Q1.5711.00
454_R461_E1.5691.00
755_I813_V1.5571.00
85_S90_S1.5521.00
745_L750_L1.5491.00
233_I239_L1.5471.00
597_Y612_A1.5421.00
141_S308_T1.5371.00
412_L504_F1.5341.00
851_A855_K1.5301.00
206_I242_M1.5261.00
450_D454_R1.5201.00
29_A407_L1.5171.00
188_K295_T1.5171.00
914_S952_A1.5161.00
444_R979_T1.5151.00
442_I521_A1.5141.00
507_A511_V1.5091.00
77_G100_K1.5081.00
180_V300_K1.5081.00
597_Y615_A1.5071.00
711_D714_K1.5031.00
551_V554_W1.4991.00
324_A329_V1.4981.00
241_N289_K1.4961.00
721_D851_A1.4951.00
855_K858_K1.4851.00
81_V94_I1.4811.00
715_I855_K1.4781.00
187_F192_L1.4771.00
500_L504_F1.4761.00
575_F578_P1.4731.00
895_Y908_P1.4721.00
10_K453_L1.4701.00
204_Q208_G1.4701.00
608_A646_A1.4571.00
767_P779_D1.4551.00
570_L574_L1.4531.00
50_T65_T1.4511.00
547_I550_K1.4491.00
599_P611_E1.4481.00
200_D204_Q1.4431.00
334_K338_K1.4381.00
738_F816_V1.4381.00
101_D104_K1.4371.00
50_T122_A1.4331.00
714_K718_D1.4301.00
147_D346_G1.4301.00
191_K195_Y1.4301.00
704_D708_T1.4271.00
875_D878_D1.4241.00
434_D950_T1.4211.00
365_T368_S1.4201.00
170_V318_I1.4201.00
665_N669_E1.4201.00
354_D357_E1.4191.00
619_L625_V1.4181.00
603_E607_E1.4161.00
204_Q207_Q1.4111.00
661_K665_N1.4111.00
227_V763_T1.4081.00
201_T204_Q1.4081.00
801_T807_E1.4081.00
563_S1038_V1.4041.00
768_L782_I1.4021.00
970_R974_L1.4001.00
405_A505_A1.4001.00
17_L896_L1.3991.00
617_K620_L1.3981.00
802_S806_Q1.3971.00
618_I622_R1.3841.00
847_A850_A1.3791.00
597_Y646_A1.3791.00
201_T801_T1.3761.00
289_K292_D1.3741.00
46_L109_A1.3741.00
445_R448_L1.3741.00
37_S590_E1.3721.00
233_I242_M1.3721.00
438_V463_T1.3721.00
143_S348_N1.3681.00
198_D801_T1.3671.00
668_K671_Q1.3601.00
669_E672_K1.3601.00
615_A674_S1.3601.00
711_D715_I1.3601.00
48_I72_V1.3581.00
547_I551_V1.3571.00
559_K1041_K1.3561.00
208_G746_S1.3561.00
50_T68_V1.3521.00
960_I964_A1.3511.00
100_K105_A1.3511.00
69_E827_K1.3511.00
613_E616_E1.3501.00
168_E332_D1.3461.00
375_I379_V1.3441.00
408_V412_L1.3401.00
800_I813_V1.3401.00
625_V650_I1.3361.00
191_K194_E1.3361.00
161_V165_E1.3331.00
142_V160_L1.3321.00
610_N614_K1.3321.00
616_E620_L1.3311.00
60_V85_S1.3291.00
564_I568_L1.3251.00
243_R287_T1.3221.00
64_V122_A1.3211.00
699_G865_V1.3201.00
709_V727_S1.3191.00
378_I395_V1.3191.00
992_I1018_I1.3111.00
850_A854_K1.3111.00
624_H653_E1.3101.00
632_L646_A1.3101.00
201_T245_P1.3091.00
548_Y552_L1.3071.00
56_T59_Q1.3061.00
700_D865_V1.3051.00
332_D336_E1.3031.00
961_H964_A1.3021.00
963_E1040_A1.3021.00
714_K717_K1.2961.00
25_A407_L1.2951.00
571_L575_F1.2871.00
575_F579_L1.2851.00
992_I1022_I1.2831.00
400_L516_L1.2821.00
22_V404_I1.2801.00
722_L838_G1.2751.00
305_V609_E1.2731.00
238_D241_N1.2731.00
661_K666_V1.2721.00
80_V95_E1.2711.00
66_K827_K1.2701.00
971_E975_E1.2691.00
306_S315_G1.2691.00
694_T835_D1.2691.00
549_K975_E1.2681.00
583_S932_T1.2641.00
72_V109_A1.2631.00
50_T125_P1.2621.00
618_I676_R1.2591.00
80_V829_D1.2591.00
48_I94_I1.2581.00
154_K778_L1.2561.00
16_W905_A1.2541.00
7_F14_A1.2491.00
948_V1024_S1.2481.00
30_G367_L1.2481.00
698_Y868_D1.2471.00
61_A827_K1.2461.00
46_L106_K1.2461.00
9_L460_R1.2431.00
192_L202_V1.2411.00
620_L628_V1.2381.00
77_G97_D1.2341.00
572_G576_L1.2331.00
719_E855_K1.2301.00
628_V648_F1.2301.00
856_I867_I1.2291.00
750_L803_A1.2281.00
163_K343_D1.2281.00
696_Y828_R1.2261.00
697_V836_V1.2251.00
461_E464_K1.2221.00
969_T973_L1.2211.00
549_K974_L1.2211.00
926_L937_A1.2211.00
155_Q159_S1.2201.00
336_E340_F1.2191.00
331_D334_K1.2171.00
337_L349_Y1.2161.00
959_V973_L1.2131.00
9_L519_M1.2111.00
29_A410_Q1.2091.00
186_S295_T1.2081.00
445_R461_E1.2061.00
698_Y833_Y1.2061.00
967_L971_E1.2021.00
794_D797_N1.2011.00
624_H666_V1.1991.00
922_A941_M1.1971.00
599_P608_A1.1971.00
6_N464_K1.1961.00
579_L927_Y1.1961.00
564_I571_L1.1961.00
593_M667_L1.1951.00
961_H965_E1.1931.00
240_K295_T1.1921.00
335_A339_K1.1851.00
735_E821_T1.1841.00
441_N958_R1.1811.00
112_A115_N1.1781.00
612_A632_L1.1781.00
555_A1034_I1.1771.00
60_V90_S1.1771.00
996_I1018_I1.1741.00
61_A825_V1.1731.00
715_I859_L1.1711.00
72_V81_V1.1711.00
719_E854_K1.1671.00
673_Q676_R1.1651.00
170_V329_V1.1651.00
338_K342_E1.1611.00
696_Y833_Y1.1591.00
215_L229_V1.1581.00
71_A116_V1.1561.00
854_K858_K1.1551.00
671_Q675_D1.1551.00
550_K553_N1.1551.00
663_K667_L1.1541.00
217_L224_E1.1521.00
622_R666_V1.1521.00
681_S684_F1.1521.00
78_V81_V1.1511.00
546_N550_K1.1501.00
712_I836_V1.1481.00
550_K554_W1.1471.00
414_I420_T1.1461.00
68_V113_L1.1451.00
202_V293_I1.1421.00
138_L333_V1.1421.00
626_D651_K1.1411.00
365_T1010_S1.1411.00
536_A539_H1.1381.00
770_T779_D1.1371.00
243_R289_K1.1361.00
164_L173_V1.1361.00
140_L351_A1.1331.00
831_K866_S1.1331.00
611_E614_K1.1321.00
79_S878_D1.1271.00
163_K340_F1.1251.00
672_K675_D1.1251.00
23_T27_L1.1231.00
931_E1011_K1.1231.00
760_M766_E1.1211.00
870_G874_A1.1211.00
142_V349_Y1.1171.00
753_S757_Q1.1161.00
542_G546_N1.1161.00
985_L989_I1.1131.00
205_V242_M1.1121.00
19_T516_L1.1121.00
143_S311_K1.1111.00
474_T510_L1.1071.00
571_L574_L1.1051.00
335_A338_K1.1051.00
325_N328_E1.1051.00
881_T884_G1.1041.00
405_A504_F1.1041.00
614_K618_I1.1021.00
975_E978_S1.1021.00
241_N743_E1.1011.00
552_L556_L1.1001.00
618_I621_D1.0991.00
330_A356_A1.0971.00
874_A878_D1.0961.00
828_R870_G1.0921.00
146_K346_G1.0901.00
149_L179_Q1.0901.00
360_T364_D1.0881.00
716_M722_L1.0871.00
4_V8_V1.0861.00
52_Y55_A1.0841.00
475_I897_V1.0791.00
761_S766_E1.0791.00
958_R962_K1.0771.00
704_D865_V1.0761.00
173_V316_I1.0761.00
567_V571_L1.0751.00
140_L349_Y1.0751.00
576_L924_V1.0731.00
339_K342_E1.0721.00
583_S934_S1.0701.00
396_V520_L1.0691.00
710_K714_K1.0671.00
14_A900_I1.0671.00
153_T178_Q1.0651.00
561_I564_I1.0651.00
341_K349_Y1.0641.00
960_I963_E1.0641.00
697_V865_V1.0631.00
610_N613_E1.0621.00
195_Y288_V1.0611.00
521_A525_F1.0571.00
799_K807_E1.0561.00
142_V152_L1.0521.00
71_A115_N1.0521.00
742_Q752_A1.0521.00
783_K789_Y1.0511.00
145_D346_G1.0511.00
8_V15_V1.0511.00
477_T950_T1.0501.00
82_T95_E1.0491.00
934_S937_A1.0491.00
963_E969_T1.0481.00
852_I869_T1.0451.00
110_A114_E1.0441.00
989_I993_G1.0411.00
473_S510_L1.0391.00
200_D754_Q1.0381.00
84_T93_M1.0371.00
397_S435_S1.0371.00
441_N445_R1.0371.00
593_M670_I1.0361.00
81_V830_G1.0361.00
697_V705_I1.0331.00
184_E783_K1.0311.00
666_V669_E1.0291.00
69_E83_S1.0281.00
616_E630_Y1.0271.00
228_V735_E1.0251.00
665_N668_K1.0241.00
992_I1021_L1.0231.00
717_K725_V1.0221.00
981_L985_L1.0211.00
703_N706_K1.0211.00
290_L294_A1.0201.00
539_H543_R1.0201.00
840_V848_V1.0201.00
307_R613_E1.0201.00
664_D668_K1.0201.00
83_S827_K1.0201.00
925_G1015_V1.0161.00
186_S785_E1.0161.00
135_F142_V1.0151.00
924_V928_V1.0111.00
917_F1027_L1.0111.00
141_S313_S1.0101.00
902_F953_I1.0091.00
48_I68_V1.0091.00
697_V708_T1.0071.00
988_A1025_T1.0071.00
555_A1030_L1.0061.00
708_T861_H1.0061.00
699_G704_D1.0041.00
23_T400_L1.0021.00
397_S517_V1.0021.00
472_S897_V1.0001.00
619_L648_F1.0001.00
443_Y447_R0.9981.00
555_A562_T0.9981.00
566_A1031_I0.9971.00
557_S560_W0.9961.00
560_W564_I0.9951.00
49_S89_A0.9951.00
675_D678_E0.9941.00
695_Y716_M0.9931.00
653_E658_D0.9931.00
396_V516_L0.9931.00
289_K743_E0.9921.00
215_L759_L0.9921.00
695_Y867_I0.9891.00
958_R979_T0.9881.00
104_K108_E0.9861.00
565_I572_G0.9851.00
408_V508_A0.9841.00
537_K541_P0.9841.00
797_N811_G0.9781.00
239_L780_V0.9771.00
615_A648_F0.9761.00
446_M452_P0.9741.00
51_T89_A0.9731.00
33_M406_L0.9701.00
848_V851_A0.9701.00
721_D841_T0.9691.00
441_N466_M0.9691.00
244_I288_V0.9691.00
224_E303_E0.9681.00
308_T313_S0.9671.00
330_A334_K0.9661.00
693_L852_I0.9661.00
750_L755_I0.9651.00
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473_S988_A0.5030.93
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134_S144_S0.5020.93
452_P527_K0.5010.93
894_V949_V0.5010.93
691_N726_N0.5010.93
430_R950_T0.5000.93
508_A511_V0.5000.93
60_V65_T0.5000.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4k0jA 3 0.9087 100 0.22 Contact Map
3ne5A 3 0.9354 100 0.296 Contact Map
4mt1A 3 0.9316 100 0.301 Contact Map
3w9iA 3 0.9468 100 0.306 Contact Map
4dx5A 3 0.9534 100 0.319 Contact Map
3aqpA 1 0.6568 100 0.728 Contact Map
4r86A 1 0.269 100 0.763 Contact Map
2ew9A 1 0.1416 86.4 0.981 Contact Map
4q2lA 1 0.0608 75.7 0.983 Contact Map
4n8nA 1 0.0951 71.2 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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