GREMLIN Database
YDZE - Putative permease-like protein YdzE
UniProt: O31493 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 78 (68)
Sequences: 9117 (6668)
Seq/√Len: 808.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
17_H21_L2.8051.00
51_G54_F2.6461.00
17_H20_Q2.5411.00
19_L27_G2.1121.00
42_G48_E2.0761.00
66_L70_K2.0571.00
23_N26_S2.0561.00
33_F37_V1.8831.00
22_L26_S1.8621.00
43_W50_I1.7541.00
42_G46_L1.6491.00
4_G9_A1.6131.00
12_F15_W1.5911.00
18_G27_G1.5871.00
52_G56_I1.5381.00
5_I10_C1.5191.00
41_L45_L1.5171.00
18_G22_L1.4851.00
11_A15_W1.3791.00
8_T12_F1.3671.00
50_I55_W1.3621.00
55_W59_F1.3211.00
59_F63_S1.3001.00
13_L17_H1.2721.00
11_A31_F1.2491.00
14_L18_G1.2481.00
8_T11_A1.2211.00
39_T58_S1.2201.00
22_L27_G1.2161.00
48_E54_F1.1731.00
19_L23_N1.1381.00
6_V10_C1.1141.00
36_L61_I1.0941.00
39_T50_I1.0871.00
15_W19_L1.0621.00
13_L16_N1.0561.00
36_L58_S1.0001.00
18_G24_A0.9781.00
40_L44_I0.9761.00
52_G55_W0.9731.00
12_F16_N0.9531.00
32_F65_V0.9441.00
51_G55_W0.9031.00
30_F34_Q0.8631.00
23_N27_G0.8521.00
9_A13_L0.8511.00
58_S62_L0.8471.00
56_I59_F0.8461.00
63_S66_L0.8411.00
43_W47_G0.8341.00
12_F38_G0.8021.00
29_L68_V0.7941.00
44_I47_G0.7921.00
26_S69_I0.7771.00
49_Q52_G0.7601.00
35_P38_G0.7521.00
14_L17_H0.7491.00
24_A28_G0.7451.00
38_G42_G0.7421.00
56_I60_L0.7381.00
40_L43_W0.7371.00
18_G32_F0.7351.00
7_S11_A0.7221.00
43_W46_L0.7171.00
37_V41_L0.7161.00
10_C14_L0.7101.00
11_A38_G0.7091.00
38_G41_L0.7021.00
56_I63_S0.6821.00
5_I9_A0.6741.00
34_Q37_V0.6621.00
28_G32_F0.6571.00
61_I64_G0.6531.00
9_A28_G0.6511.00
11_A16_N0.6471.00
22_L25_S0.6361.00
53_T56_I0.6261.00
52_G59_F0.6251.00
8_T61_I0.6191.00
16_N19_L0.6061.00
27_G31_F0.6001.00
7_S12_F0.5921.00
34_Q61_I0.5901.00
49_Q53_T0.5761.00
63_S67_L0.5701.00
29_L39_T0.5691.00
32_F68_V0.5661.00
43_W49_Q0.5631.00
8_T34_Q0.5551.00
11_A34_Q0.5541.00
33_F36_L0.5501.00
7_S30_F0.5361.00
32_F62_L0.5331.00
11_A24_A0.5321.00
33_F65_V0.5261.00
15_W32_F0.5251.00
16_N20_Q0.5241.00
39_T43_W0.5231.00
53_T70_K0.5221.00
56_I67_L0.5151.00
65_V69_I0.5131.00
54_F58_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2i68A 2 0.7564 99 0.342 Contact Map
3b5dA 2 0.9231 98.5 0.452 Contact Map
3aqpA 1 0.9744 8.6 0.865 Contact Map
4dx5A 3 0.9872 6.1 0.873 Contact Map
4k0jA 3 0.9487 6 0.874 Contact Map
4mt1A 3 0.9744 5.9 0.875 Contact Map
4pd6A 3 0.3205 5.6 0.875 Contact Map
3w9iA 3 0.9872 5.3 0.877 Contact Map
3ne5A 3 0.9872 4.8 0.88 Contact Map
4pgrA 1 0.9872 4.1 0.884 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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